☰

A Douglas Kinghorn - Publications

Affiliations: 
Chemistry Ohio State University, Columbus, Columbus, OH 
 University of Illinois at Chicago, Chicago, IL, United States 
Area:
Pharmacology, Alternative Medicine, Oncology
Website:
http://pharmacy.osu.edu/faculty-staff/users/kinghorn4
Tree Info Similar researchers PubMed Report error

368 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Ren Y, Kaweesa EN, Henkin JM, Sydara K, Xayvue M, Pandey P, Chittiboyina AG, Ali Z, Ferreira D, Soejarto DD, Burdette JE, Kinghorn AD. Cytotoxic leuconoxine-type diazaspiroindole alkaloids isolated from Cryptolepis dubia. Bioorganic & Medicinal Chemistry Letters. 129650. PMID 38341161 DOI: 10.1016/j.bmcl.2024.129650  0.342
2023 Lindsay CA, Kinghorn AD, Rakotondraibe HL. Bioactive and unusual steroids from Penicillium fungi. Phytochemistry. 113638. PMID 36914145 DOI: 10.1016/j.phytochem.2023.113638  0.321
2022 Blanco Carcache PJ, Anaya Eugenio GD, Ninh TN, Moore CE, Rivera-Chávez J, Ren Y, Soejarto DD, Kinghorn AD. Cytotoxic constituents of Glycosmis ovoidea collected in Vietnam. Fitoterapia. 162: 105265. PMID 35963484 DOI: 10.1016/j.fitote.2022.105265  0.383
2022 Diaz-Allen C, Spjut RW, Kinghorn AD, Rakotondraibe HL. Prioritizing natural product compounds using 1D-TOCSY NMR spectroscopy. Trends in Organic Chemistry. 22: 99-114. PMID 35475303  0.319
2022 Aldrich LN, Burdette JE, Carcache de Blanco E, Coss CC, Eustaquio AS, Fuchs JR, Kinghorn AD, MacFarlane A, Mize BK, Oberlies NH, Orjala J, Pearce CJ, Phelps MA, Rakotondraibe LH, Ren Y, et al. Discovery of Anticancer Agents of Diverse Natural Origin. Journal of Natural Products. PMID 35213158 DOI: 10.1021/acs.jnatprod.2c00036  0.338
2021 Ren Y, Elkington BG, Henkin JM, Sydara K, Kinghorn AD, Soejarto DD. Bioactive small-molecule constituents of Lao plants. Journal of Medicinal Plant Research. 15: 540-559. PMID 35178192 DOI: 10.5897/jmpr2021.7137  0.311
2021 Ren Y, Kinghorn AD. Antitumor potential of the protein phosphatase inhibitor, cantharidin, and selected derivatives. Bioorganic & Medicinal Chemistry. 32: 116012. PMID 33454654 DOI: 10.1016/j.bmc.2021.116012  0.303
2020 Ren Y, Kinghorn AD. Development of Potential Antitumor Agents from the Scaffolds of Plant-Derived Terpenoid Lactones. Journal of Medicinal Chemistry. 63: 15410-15448. PMID 33289552 DOI: 10.1021/acs.jmedchem.0c01449  0.314
2020 Zhang Y, Tan CY, Spjut RW, Fuchs JR, Kinghorn AD, Rakatondraibe LH. Specialized metabolites of the United States lichen Niebla homalea and their antiproliferative activities. Phytochemistry. 180: 112521. PMID 33099129 DOI: 10.1016/j.phytochem.2020.112521  0.363
2020 Ren Y, Ribas HT, Heath K, Wu S, Ren J, Shriwas P, Chen X, Johnson ME, Cheng X, Burdette JE, Kinghorn AD. Na/K-ATPase-Targeted Cytotoxicity of (+)-Digoxin and Several Semisynthetic Derivatives. Journal of Natural Products. PMID 32096998 DOI: 10.1021/Acs.Jnatprod.9B01060  0.32
2020 Ren Y, Tan Q, Heath K, Wu S, Wilson JR, Ren J, Shriwas P, Yuan C, Ngoc Ninh T, Chai HB, Chen X, Soejarto DD, Johnson ME, Cheng X, Burdette JE, ... Kinghorn AD, et al. Cytotoxic and non-cytotoxic cardiac glycosides isolated from the combined flowers, leaves, and twigs of Streblus asper. Bioorganic & Medicinal Chemistry. 115301. PMID 31953129 DOI: 10.1016/J.Bmc.2019.115301  0.322
2019 Chang LS, Oblinger JL, Burns SS, Huang J, Anderson LW, Hollingshead MG, Shen R, Pan L, Agarwal G, Ren Y, Roberts RD, O'Keefe BR, Kinghorn AD, Collins JM. Targeting protein translation by rocaglamide and didesmethylrocaglamide to treat MPNST and other sarcomas. Molecular Cancer Therapeutics. PMID 31848295 DOI: 10.1158/1535-7163.Mct-19-0809  0.324
2019 Agarwal G, Wilson JR, Kurina SJ, Anaya-Eugenio GD, Ninh TN, Burdette JE, Soejarto DD, Cheng X, Carcache de Blanco EJ, Rakotondraibe LH, Kinghorn AD. Structurally Modified Cyclopenta[]benzofuran Analogues Isolated from . Journal of Natural Products. PMID 31621322 DOI: 10.1021/Acs.Jnatprod.9B00631  0.513
2019 Tan CY, Wang F, Anaya-Eugenio GD, Gallucci JC, Goughenour KD, Rappleye CA, Spjut RW, Carcache de Blanco EJ, Kinghorn AD, Rakotondraibe LH. α-Pyrone and Sterol Constituents of , a Fungal Associate of the Lichen . Journal of Natural Products. PMID 31465222 DOI: 10.1021/Acs.Jnatprod.9B00340  0.427
2019 Soejarto DD, Addo EM, Kinghorn AD. Highly sweet compounds of plant origin: From ethnobotanical observations to wide utilization. Journal of Ethnopharmacology. 112056. PMID 31279071 DOI: 10.1016/J.Jep.2019.112056  0.361
2019 Anaya-Eugenio GD, Addo EM, Ezzone N, Henkin JM, Ninh TN, Ren Y, Soejarto DD, Kinghorn AD, Carcache de Blanco EJ. Caspase-Dependent Apoptosis in Prostate Cancer Cells and Zebrafish by Corchorusoside C from Streptocaulon juventas. Journal of Natural Products. PMID 31120251 DOI: 10.1021/Acs.Jnatprod.9B00140  0.345
2019 Ren Y, de Blanco EJC, Fuchs JR, Soejarto DD, Burdette JE, Swanson SM, Kinghorn AD. Potential Anticancer Agents Characterized from Selected Tropical Plants. Journal of Natural Products. PMID 30830783 DOI: 10.1021/Acs.Jnatprod.9B00018  0.45
2019 Benatrehina PA, Chen WL, Czarnecki AA, Kurina S, Chai HB, Lantvit DD, Ninh TN, Zhang X, Soejarto DD, Burdette JE, Kinghorn AD, Rakotondraibe LH. Bioactivity-Guided Isolation of Totarane-Derived Diterpenes from Podocarpus neriifolius and Structure Revision of 3-Deoxy-2α-hydroxynagilactone E. Natural Products and Bioprospecting. PMID 30783922 DOI: 10.1007/S13659-019-0198-X  0.483
2019 Ren Y, Kinghorn AD. Natural Product Triterpenoids and Their Semi-Synthetic Derivatives with Potential Anticancer Activity. Planta Medica. 85: 802-814. PMID 30658371 DOI: 10.1055/A-0832-2383  0.397
2018 Kearney SE, Zahoránszky-Kőhalmi G, Brimacombe KR, Henderson MJ, Lynch C, Zhao T, Wan KK, Itkin Z, Dillon C, Shen M, Cheff DM, Lee TD, Bougie D, Cheng K, Coussens NP, ... ... Kinghorn AD, et al. Canvass: A Crowd-Sourced, Natural-Product Screening Library for Exploring Biological Space. Acs Central Science. 4: 1727-1741. PMID 30648156 DOI: 10.1021/Acscentsci.8B00747  0.419
2018 Kao D, Henkin JM, Soejarto DD, Kinghorn AD, Oberlies NH. Non-Destructive Chemical Analysis of a L. (Mangosteen) Herbarium Voucher Specimen. Phytochemistry Letters. 28: 124-129. PMID 30613309 DOI: 10.1016/J.Phytol.2018.10.001  0.3
2018 Henkin JM, Ren Y, Soejarto DD, Kinghorn AD. The Search for Anticancer Agents from Tropical Plants. Progress in the Chemistry of Organic Natural Products. 107: 1-94. PMID 30178270 DOI: 10.1007/978-3-319-93506-5_1  0.32
2018 Ren Y, Anaya-Eugenio GD, Czarnecki AA, Ninh TN, Yuan C, Chai HB, Soejarto DD, Burdette JE, de Blanco EJC, Kinghorn AD. Cytotoxic and NF-κB and mitochondrial transmembrane potential inhibitory pentacyclic triterpenoids from Syzygium corticosum and their semi-synthetic derivatives. Bioorganic & Medicinal Chemistry. PMID 30057155 DOI: 10.1016/J.Bmc.2018.07.025  0.44
2018 Young AN, Herrera D, Huntsman AC, Korkmaz MA, Lantvit DD, Mazumder S, Kolli S, Coss CC, King S, Wang H, Swanson SM, Kinghorn AD, Zhang X, Phelps MA, Aldrich LN, et al. Phyllanthusmin derivatives induce apoptosis and reduce tumor burden in high grade serous ovarian cancer by late-stage autophagy inhibition. Molecular Cancer Therapeutics. PMID 30018048 DOI: 10.1158/1535-7163.Mct-17-1195  0.391
2018 Benatrehina PA, Pan L, Naman CB, Li J, Kinghorn AD. Usage, biological activity, and safety of selected botanical dietary supplements consumed in the United States. Journal of Traditional and Complementary Medicine. 8: 267-277. PMID 29736381 DOI: 10.1016/J.Jtcme.2018.01.006  0.413
2018 Woodard JL, Huntsman AC, Patel PA, Chai HB, Kanagasabai R, Karmahapatra S, Young AN, Ren Y, Cole MS, Herrera D, Yalowich JC, Kinghorn AD, Burdette JE, Fuchs JR. Synthesis and antiproliferative activity of derivatives of the phyllanthusmin class of arylnaphthalene lignan lactones. Bioorganic & Medicinal Chemistry. PMID 29656990 DOI: 10.1016/J.Bmc.2018.03.033  0.456
2018 Ren Y, Gallucci JC, Li X, Chen L, Yu J, Kinghorn AD. Crystal Structures and Human Leukemia Cell Apoptosis Inducible Activities of Parthenolide Analogues Isolated from Piptocoma rufescens. Journal of Natural Products. PMID 29350920 DOI: 10.1021/Acs.Jnatprod.7B01079  0.452
2018 Young AN, Herrera D, Huntsman A, Lantvit DD, Korkmaz MA, Aldrich LN, Kinghorn AD, Fuchs JR, Burdette JE. Abstract 2672: Phyllanthusmins induce apoptosis and reduce tumor burden in high grade serous ovarian cancer by late-stage autophagy inhibition Cancer Research. 78: 2672-2672. DOI: 10.1158/1538-7445.Am2018-2672  0.373
2017 Li J, Yuan C, Pan L, Benatrehina PA, Chai H, Keller WJ, Naman CB, Kinghorn AD. Bioassay-guided Isolation of Antioxidant and Cytoprotective Constituents from a Maqui Berry (Aristotelia chilensis) Dietary Supplement Ingredient as Markers for Qualitative and Quantitative Analysis. Journal of Agricultural and Food Chemistry. PMID 28910091 DOI: 10.1021/Acs.Jafc.7B03261  0.497
2017 Oghumu S, Varikuti S, Saljoughian N, Terrazas C, Huntsman AC, Parinandi NL, Fuchs JR, Kinghorn AD, Satoskar AR. Pentalinonsterol, a Constituent of Pentalinon andrieuxii, Possesses Potent Immunomodulatory Activity and Primes T Cell Immune Responses. Journal of Natural Products. PMID 28876059 DOI: 10.1021/Acs.Jnatprod.7B00445  0.31
2017 Chen WL, Ren Y, Ren J, Erxleben C, Johnson ME, Gentile S, Kinghorn AD, Swanson SM, Burdette JE. (+)-Strebloside-Induced Cytotoxicity in Ovarian Cancer Cells Is Mediated through Cardiac Glycoside Signaling Networks. Journal of Natural Products. PMID 28234008 DOI: 10.1021/Acs.Jnatprod.6B01150  0.377
2016 Ren Y, Chen WL, Lantvit DD, Sass EJ, Shriwas P, Ninh TN, Chai HB, Zhang X, Soejarto DD, Chen X, Lucas DM, Swanson SM, Burdette JE, Kinghorn AD. Cardiac Glycoside Constituents of Streblus asper with Potential Antineoplastic Activity. Journal of Natural Products. PMID 27983842 DOI: 10.1021/Acs.Jnatprod.6B00924  0.4
2016 Kinghorn AD, DE Blanco EJ, Lucas DM, Rakotondraibe HL, Orjala J, Soejarto DD, Oberlies NH, Pearce CJ, Wani MC, Stockwell BR, Burdette JE, Swanson SM, Fuchs JR, Phelps MA, Xu L, et al. Discovery of Anticancer Agents of Diverse Natural Origin. Anticancer Research. 36: 5623-5637. PMID 27793884 DOI: 10.21873/Anticanres.11146  0.436
2016 Harms H, Kurita KL, Pan L, Wahome PG, He H, Kinghorn AD, Carter GT, Linington RG. Discovery of anabaenopeptin 679 from freshwater algal bloom material: Insights into the structure-activity relationship of anabaenopeptin protease inhibitors. Bioorganic & Medicinal Chemistry Letters. PMID 27641470 DOI: 10.1016/J.Bmcl.2016.09.008  0.378
2016 Ren Y, Benatrehina PA, Muñoz Acuña U, Yuan C, Chai HB, Ninh TN, Carcache de Blanco EJ, Soejarto DD, Kinghorn AD. Isolation of Bioactive Rotenoids and Isoflavonoids from the Fruits of Millettia caerulea. Planta Medica. PMID 27280936 DOI: 10.1055/S-0042-108059  0.835
2016 Othman N, Pan L, Mejin M, Voong JC, Chai HB, Pannell CM, Kinghorn AD, Yeo TC. Cyclopenta[b]benzofuran and Secodammarane Derivatives from the Stems of Aglaia stellatopilosa. Journal of Natural Products. PMID 26974604 DOI: 10.1021/Acs.Jnatprod.5B00810  0.496
2016 Naman CB, Gromovsky AD, Vela CM, Fletcher JN, Gupta G, Varikuti S, Zhu X, Zywot EM, Chai H, Werbovetz KA, Satoskar AR, Kinghorn AD. Antileishmanial and Cytotoxic Activity of Some Highly Oxidized Abietane Diterpenoids from the Bald Cypress, Taxodium distichum. Journal of Natural Products. PMID 26905523 DOI: 10.1021/Acs.Jnatprod.5B01131  0.763
2015 Gupta G, Peine KJ, Abdelhamid D, Snider H, Shelton AB, Rao L, Kotha SR, Huntsman AC, Varikuti S, Oghumu S, Naman CB, Pan L, Parinandi NL, Papenfuss TL, Kinghorn AD, et al. A Novel Sterol Isolated from a Plant Used by Mayan Traditional Healers Is Effective in Treatment of Visceral Leishmaniasis Caused by Leishmania donovani. Acs Infectious Diseases. 1: 497-506. PMID 27623316 DOI: 10.1021/Acsinfecdis.5B00081  0.307
2015 Ren Y, VanSchoiack A, Chai HB, Goetz M, Kinghorn AD. Cytotoxic Barrigenol-like Triterpenoids from an Extract of Cyrilla racemiflora Housed in a Repository. Journal of Natural Products. PMID 26422131 DOI: 10.1021/Acs.Jnatprod.5B00532  0.494
2015 Pan L, Muñoz Acuña U, Chai H, Park HY, Ninh TN, Thanh BV, Merino EF, Cassera MB, Rakotondraibe LH, Carcache de Blanco EJ, Soejarto DD, Kinghorn AD. New Bioactive Lupane Triterpene Coumaroyl Esters Isolated from Buxus cochinchinensis. Planta Medica. 81: 1133-40. PMID 26132853 DOI: 10.1055/S-0035-1546118  0.827
2015 Naman CB, Li J, Moser A, Hendrycks JM, Benatrehina PA, Chai H, Yuan C, Keller WJ, Kinghorn AD. Computer-Assisted Structure Elucidation of Black Chokeberry (Aronia melanocarpa) Fruit Juice Isolates with a New Fused Pentacyclic Flavonoid Skeleton. Organic Letters. 17: 2988-91. PMID 26030740 DOI: 10.1021/Acs.Orglett.5B01284  0.494
2015 Naman CB, Gupta G, Varikuti S, Chai H, Doskotch RW, Satoskar AR, Kinghorn AD. Northalrugosidine is a bisbenzyltetrahydroisoquinoline alkaloid from Thalictrum alpinum with in vivo antileishmanial activity. Journal of Natural Products. 78: 552-6. PMID 25629555 DOI: 10.1021/Np501028U  0.453
2015 Ren Y, Yuan C, Deng Y, Kanagasabai R, Ninh TN, Tu VT, Chai HB, Soejarto DD, Fuchs JR, Yalowich JC, Yu J, Kinghorn AD. Cytotoxic and natural killer cell stimulatory constituents of Phyllanthus songboiensis. Phytochemistry. 111: 132-40. PMID 25596805 DOI: 10.1016/J.Phytochem.2014.12.014  0.425
2015 Chen L, Yi L, Ren Y, Zhang J, Kinghorn AD, Caligiuri MA, Yu J. Enhancement of Natural Killer Cell Interferon-Gamma Production By the Derivatives of the Natural Product Phyllanthusmins Via TLR-Mediated NF-Kb and STAT3 Signaling Pathways Blood. 126: 1031-1031. DOI: 10.1182/Blood.V126.23.1031.1031  0.315
2014 Pan L, Terrazas C, Muñoz Acuña U, Ninh TN, Chai H, Carcache de Blanco EJ, Soejarto DD, Satoskar AR, Kinghorn AD. Bioactive indole alkaloids isolated from Alstonia angustifolia. Phytochemistry Letters. 10: 54-59. PMID 25584095 DOI: 10.1016/J.Phytol.2014.06.010  0.834
2014 Pérez LB, Still PC, Naman CB, Ren Y, Pan L, Chai HB, Carcache de Blanco EJ, Ninh TN, Van Thanh B, Swanson SM, Soejarto DD, Kinghorn AD. Investigation of Vietnamese plants for potential anticancer agents. Phytochemistry Reviews : Proceedings of the Phytochemical Society of Europe. 13: 727-739. PMID 25395897 DOI: 10.1007/S11101-014-9335-7  0.801
2014 Yong Y, Pan L, Ren Y, Fatima N, Ahmed S, Chang LC, Zhang X, Kinghorn AD, Swanson SM, Carcache de Blanco EJ. Assay development for the discovery of semaphorin 3B inducing agents from natural product sources. Fitoterapia. 98: 184-91. PMID 25016954 DOI: 10.1016/J.Fitote.2014.07.004  0.392
2014 Li J, Pan L, Fletcher JN, Lv W, Deng Y, Vincent MA, Slack JP, McCluskey TS, Jia Z, Cushman M, Kinghorn AD. In vitro evaluation of potential bitterness-masking terpenoids from the Canada goldenrod (Solidago canadensis). Journal of Natural Products. 77: 1739-43. PMID 24999828 DOI: 10.1021/Np5001413  0.76
2014 Ren Y, Lantvit DD, Deng Y, Kanagasabai R, Gallucci JC, Ninh TN, Chai HB, Soejarto DD, Fuchs JR, Yalowich JC, Yu J, Swanson SM, Kinghorn AD. Potent cytotoxic arylnaphthalene lignan lactones from Phyllanthus poilanei. Journal of Natural Products. 77: 1494-504. PMID 24937209 DOI: 10.1021/Np5002785  0.498
2014 Li J, Pan L, Naman CB, Deng Y, Chai H, Keller WJ, Kinghorn AD. Pyrrole alkaloids with potential cancer chemopreventive activity isolated from a goji berry-contaminated commercial sample of African mango. Journal of Agricultural and Food Chemistry. 62: 5054-60. PMID 24792835 DOI: 10.1021/Jf500802X  0.494
2014 Pan L, Woodard JL, Lucas DM, Fuchs JR, Kinghorn AD. Rocaglamide, silvestrol and structurally related bioactive compounds from Aglaia species. Natural Product Reports. 31: 924-39. PMID 24788392 DOI: 10.1039/C4Np00006D  0.432
2014 Bueno Pérez L, Pan L, Muñoz Acuña U, Li J, Chai HB, Gallucci JC, Ninh TN, Carcache de Blanco EJ, Soejarto DD, Kinghorn AD. Caeruleanone A, a rotenoid with a new arrangement of the D-ring from the fruits of Millettia caerulea. Organic Letters. 16: 1462-5. PMID 24552419 DOI: 10.1021/Ol500266Z  0.785
2014 Ren Y, Yuan C, Qian Y, Chai HB, Chen X, Goetz M, Kinghorn AD. Constituents of an extract of Cryptocarya rubra housed in a repository with cytotoxic and glucose transport inhibitory effects Journal of Natural Products. 77: 550-556. PMID 24344605 DOI: 10.1021/Np400809W  0.48
2013 Acuña UM, Shen Q, Ren Y, Lantvit DD, Wittwer JA, Kinghorn AD, Swanson SM, de Blanco EJ. Goyazensolide Induces Apoptosis in Cancer Cells in vitro and in vivo. International Journal of Cancer Research. 9: 36-53. PMID 25621077 DOI: 10.3923/Ijcr.2013.36.53  0.353
2013 Ren Y, Jiménez F, García R, Mejía M, Chai H, Farnsworth NR, Soejarto DD, Kinghorn AD. A cytotoxic dimeric furanoheliangolide from Piptocoma rufescens. Tetrahedron Letters. 54: 5457-5460. PMID 24159245 DOI: 10.1016/J.Tetlet.2013.07.128  0.429
2013 Li J, Pan L, Deng Y, Muñoz-Acuña U, Yuan C, Lai H, Chai H, Chagwedera TE, Farnsworth NR, Carcache de Blanco EJ, Li C, Soejarto DD, Kinghorn AD. Sphenostylisins A-K: bioactive modified isoflavonoid constituents of the root bark of Sphenostylis marginata ssp. erecta. The Journal of Organic Chemistry. 78: 10166-77. PMID 24044416 DOI: 10.1021/Jo401573H  0.492
2013 Ren Y, Chai H, Goetz M, Kinghorn AD. A cytotoxic decahydronaphthalenylpropenal derivative and tetrahydrofuran lignans from the stems of Cameraria latifolia. Tetrahedron Letters. 54: 4854-4858. PMID 23997317 DOI: 10.1016/J.Tetlet.2013.06.109  0.472
2013 Spear SA, Burns SS, Oblinger JL, Ren Y, Pan L, Kinghorn AD, Welling DB, Chang LS. Natural compounds as potential treatments of NF2-deficient schwannoma and meningioma: cucurbitacin D and goyazensolide. Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology. 34: 1519-27. PMID 23928514 DOI: 10.1097/Mao.0B013E3182956169  0.449
2013 Bueno Pérez L, Li J, Lantvit DD, Pan L, Ninh TN, Chai HB, Soejarto DD, Swanson SM, Lucas DM, Kinghorn AD. Bioactive constituents of Indigofera spicata. Journal of Natural Products. 76: 1498-504. PMID 23895019 DOI: 10.1021/Np400567C  0.806
2013 Li L, Han AR, Kinghorn AD, Frye RF, Derendorf H, Butterweck V. Pharmacokinetic properties of pure xanthones in comparison to a mangosteen fruit extract in rats. Planta Medica. 79: 646-53. PMID 23673465 DOI: 10.1055/S-0032-1328543  0.384
2013 Still PC, Yi B, González-Cestari TF, Pan L, Pavlovicz RE, Chai HB, Ninh TN, Li C, Soejarto DD, McKay DB, Kinghorn AD. Alkaloids from Microcos paniculata with cytotoxic and nicotinic receptor antagonistic activities. Journal of Natural Products. 76: 243-9. PMID 23327794 DOI: 10.1021/Np3007414  0.812
2013 Pan L, Acuña UM, Li J, Jena N, Ninh TN, Pannell CM, Chai H, Fuchs JR, Carcache de Blanco EJ, Soejarto DD, Kinghorn AD. Bioactive flavaglines and other constituents isolated from Aglaia perviridis. Journal of Natural Products. 76: 394-404. PMID 23301897 DOI: 10.1021/Np3007588  0.559
2013 Bueno Pérez L, Pan L, Sass E, Gupta SV, Lehman A, Kinghorn AD, Lucas DM. Potentiating effect of the flavonolignan (-)-hydnocarpin in combination with vincristine in a sensitive and P-gp-expressing acute lymphoblastic leukemia cell line. Phytotherapy Research : Ptr. 27: 1735-8. PMID 23280566 DOI: 10.1002/Ptr.4903  0.759
2013 Chitchumroonchokchai C, Thomas-Ahner JM, Li J, Riedl KM, Nontakham J, Suksumrarn S, Clinton SK, Kinghorn AD, Failla ML. Anti-tumorigenicity of dietary α-mangostin in an HT-29 colon cell xenograft model and the tissue distribution of xanthones and their phase II metabolites. Molecular Nutrition & Food Research. 57: 203-11. PMID 23239542 DOI: 10.1002/Mnfr.201200539  0.352
2013 Endeshaw M, Zhu X, He S, Pandharkar T, Cason E, Mahasenan KV, Agarwal H, Li C, Munde M, Wilson WD, Bahar M, Doskotch RW, Kinghorn AD, Kaiser M, Brun R, et al. 8,8-dialkyldihydroberberines with potent antiprotozoal activity. Journal of Natural Products. 76: 311-5. PMID 23167812 DOI: 10.1021/Np300638F  0.543
2012 Ren Y, Wei M, Still PC, Yuan S, Deng Y, Chen X, Himmeldirk K, Kinghorn AD, Yu J. Synthesis and Antitumor Activity of Ellagic Acid Peracetate. Acs Medicinal Chemistry Letters. 3: 631-636. PMID 23185648 DOI: 10.1021/Ml300065Z  0.791
2012 Li J, Deng Y, Yuan C, Pan L, Chai H, Keller WJ, Kinghorn AD. Antioxidant and quinone reductase-inducing constituents of black chokeberry (Aronia melanocarpa) fruits. Journal of Agricultural and Food Chemistry. 60: 11551-9. PMID 23131110 DOI: 10.1021/Jf303712E  0.514
2012 Pearce CJ, Lantvit DD, Shen Q, Jarjoura D, Zhang X, Oberlies NH, Kroll DJ, Wani MC, Orjala J, Soejarto DD, Farnsworth NR, de Blanco EJ, Fuchs JR, Kinghorn AD, Swanson SM. Use of the hollow fiber assay for the discovery of novel anticancer agents from fungi. Methods in Molecular Biology (Clifton, N.J.). 944: 267-77. PMID 23065624 DOI: 10.1007/978-1-62703-122-6_20  0.311
2012 El-Elimat T, Zhang X, Jarjoura D, Moy FJ, Orjala J, Kinghorn AD, Pearce CJ, Oberlies NH. Chemical Diversity of Metabolites from Fungi, Cyanobacteria, and Plants Relative to FDA-Approved Anticancer Agents. Acs Medicinal Chemistry Letters. 3: 645-649. PMID 22993669 DOI: 10.1021/Ml300105S  0.345
2012 Pan L, Lezama-Davila CM, Isaac-Marquez AP, Calomeni EP, Fuchs JR, Satoskar AR, Kinghorn AD. Sterols with antileishmanial activity isolated from the roots of Pentalinon andrieuxii. Phytochemistry. 82: 128-35. PMID 22840389 DOI: 10.1016/J.Phytochem.2012.06.012  0.512
2012 Alinari L, Prince CJ, Edwards RB, Towns WH, Mani R, Lehman A, Zhang X, Jarjoura D, Pan L, Kinghorn AD, Grever MR, Baiocchi RA, Lucas DM. Dual targeting of the cyclin/Rb/E2F and mitochondrial pathways in mantle cell lymphoma with the translation inhibitor silvestrol. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 4600-11. PMID 22791882 DOI: 10.1158/1078-0432.Ccr-12-0839  0.312
2012 Ren Y, Acuña UM, Jiménez F, García R, Mejía M, Chai H, Gallucci JC, Farnsworth NR, Soejarto DD, Carcache de Blanco EJ, Kinghorn AD. Cytotoxic and NF-κB inhibitory sesquiterpene lactones from Piptocoma rufescens. Tetrahedron. 68: 2671-2678. PMID 22685350 DOI: 10.1016/J.Tet.2012.01.061  0.481
2012 Kang HS, Santarsiero BD, Kim H, Krunic A, Shen Q, Swanson SM, Chai H, Kinghorn AD, Orjala J. Merocyclophanes A and B, antiproliferative cyclophanes from the cultured terrestrial Cyanobacterium Nostoc sp. Phytochemistry. 79: 109-15. PMID 22571940 DOI: 10.1016/J.Phytochem.2012.03.005  0.405
2012 Pan L, Terrazas C, Lezama-Davila CM, Rege N, Gallucci JC, Satoskar AR, Kinghorn AD. Cordifolide A, a sulfur-containing clerodane diterpene glycoside from Tinospora cordifolia. Organic Letters. 14: 2118-21. PMID 22497272 DOI: 10.1021/Ol300657H  0.457
2012 Jones WP, Kinghorn AD. Extraction of plant secondary metabolites. Methods in Molecular Biology (Clifton, N.J.). 864: 341-66. PMID 22367903 DOI: 10.1007/978-1-61779-624-1_13  0.401
2012 Pan L, Yong Y, Deng Y, Lantvit DD, Ninh TN, Chai H, Carcache de Blanco EJ, Soejarto DD, Swanson SM, Kinghorn AD. Isolation, structure elucidation, and biological evaluation of 16,23-epoxycucurbitacin constituents from Eleaocarpus chinensis. Journal of Natural Products. 75: 444-52. PMID 22239601 DOI: 10.1021/Np200879P  0.456
2012 Yong Y, Pan L, Ren Y, Kinghorn AD, Swanson SM, Blanco EJCd. Abstract 2837: Assay development for the discovery of semaphorin 3B-inducing agents from natural product sources Cancer Research. 72: 2837-2837. DOI: 10.1158/1538-7445.Am2012-2837  0.4
2012 Yang J, Shen Q, Newman DJ, Kinghorn AD, Swanson SM. Abstract 2815: Sylvestrol inhibits protein synthesis by downregulating the AKT/mTOR pathway Cancer Research. 72: 2815-2815. DOI: 10.1158/1538-7445.Am2012-2815  0.31
2011 Fletcher JN, Kinghorn AD, Slack JP, McCluskey TS, Odley A, Jia Z. In vitro evaluation of flavonoids from Eriodictyon californicum for antagonist activity against the bitterness receptor hTAS2R31. Journal of Agricultural and Food Chemistry. 59: 13117-21. PMID 22059530 DOI: 10.1021/Jf204359Q  0.733
2011 Pan L, Matthew S, Lantvit DD, Zhang X, Ninh TN, Chai H, Carcache de Blanco EJ, Soejarto DD, Swanson SM, Kinghorn AD. Bioassay-guided isolation of constituents of Piper sarmentosum using a mitochondrial transmembrane potential assay. Journal of Natural Products. 74: 2193-9. PMID 21973101 DOI: 10.1021/Np200557E  0.431
2011 Deng Y, Chin YW, Chai HB, de Blanco EC, Kardono LB, Riswan S, Soejarto DD, Farnsworth NR, Kinghorn AD. Phytochemical and Bioactivity Studies on Constituents of the Leaves of Vitex Quinata. Phytochemistry Letters. 4: 213-217. PMID 21966342 DOI: 10.1016/J.Phytol.2011.03.007  0.481
2011 Kinghorn AD, Pan L, Fletcher JN, Chai H. The relevance of higher plants in lead compound discovery programs. Journal of Natural Products. 74: 1539-55. PMID 21650152 DOI: 10.1021/Np200391C  0.737
2011 D'Ambrosio SM, Han C, Pan L, Kinghorn AD, Ding H. Aliphatic acetogenin constituents of avocado fruits inhibit human oral cancer cell proliferation by targeting the EGFR/RAS/RAF/MEK/ERK1/2 pathway. Biochemical and Biophysical Research Communications. 409: 465-9. PMID 21596018 DOI: 10.1016/J.Bbrc.2011.05.027  0.41
2011 Gupta SV, Sass EJ, Davis ME, Edwards RB, Lozanski G, Heerema NA, Lehman A, Zhang X, Jarjoura D, Byrd JC, Pan L, Chan KK, Kinghorn AD, Phelps MA, Grever MR, et al. Resistance to the translation initiation inhibitor silvestrol is mediated by ABCB1/P-glycoprotein overexpression in acute lymphoblastic leukemia cells. The Aaps Journal. 13: 357-64. PMID 21538216 DOI: 10.1208/S12248-011-9276-7  0.315
2011 Bahar M, Deng Y, Zhu X, He S, Pandharkar T, Drew ME, Navarro-Vázquez A, Anklin C, Gil RR, Doskotch RW, Werbovetz KA, Kinghorn AD. Potent antiprotozoal activity of a novel semi-synthetic berberine derivative. Bioorganic & Medicinal Chemistry Letters. 21: 2606-10. PMID 21474310 DOI: 10.1016/J.Bmcl.2011.01.101  0.702
2011 Ren Y, Matthew S, Lantvit DD, Ninh TN, Chai H, Fuchs JR, Soejarto DD, de Blanco EJ, Swanson SM, Kinghorn AD. Cytotoxic and NF-κB inhibitory constituents of the stems of Cratoxylum cochinchinense and their semisynthetic analogues. Journal of Natural Products. 74: 1117-25. PMID 21428375 DOI: 10.1021/Np200051J  0.445
2011 Ren Y, Yuan C, Chai HB, Ding Y, Li XC, Ferreira D, Kinghorn AD. Absolute configuration of (-)-gambogic acid, an antitumor agent. Journal of Natural Products. 74: 460-3. PMID 21067206 DOI: 10.1021/Np100422Z  0.335
2011 Kinghorn AD, Chai HB, Sung CK, Keller WJ. The classical drug discovery approach to defining bioactive constituents of botanicals. Fitoterapia. 82: 71-9. PMID 20804827 DOI: 10.1016/J.Fitote.2010.08.015  0.497
2011 Alinari L, Edwards RB, Prince CJ, Towns WH, Mani R, Lehman A, Zhang X, Jarjoura D, Pan L, Kinghorn AD, Grever MR, Baiocchi RA, Lucas DM. Targeting the Cyclin D - CDK4/6 - Rb Axis in Mantle Cell Lymphoma with the Novel Translation Inhibitor Silvestrol, Blood. 118: 3498-3498. DOI: 10.1182/Blood.V118.21.3498.3498  0.327
2011 Alachkar H, Santhanam R, Lucas DM, Schwind S, Hickey C, Pang J, Perrotti D, Pan L, Kinghorn AD, Marcucci G, Grever MR. Translational Research From the Tropical Forest: Silvestrol, a Natural Product From the Plant Aglaia Foveolata inhibits the Expression of Tyrosine Kinases and Shows a Significant In Vivo Activity in Acute Myeloid Leukemia (AML) Blood. 118: 2616-2616. DOI: 10.1182/Blood.V118.21.2616.2616  0.323
2011 Patton JT, Lustberg ME, Garman SL, Kinghorn AD, Pan L, Lucas DM, Grever MR, Baiocchi RA. Silvestrol Modulates Direct Anti-Tumor Activity Against Epstein-Barr Virus (EBV)-Associated Lymphomas While Sparing Innate and Antigen Specific Adaptive Immunity Blood. 118: 104-104. DOI: 10.1182/Blood.V118.21.104.104  0.303
2011 Matthew S, Pan L, Shen Q, Kinghorn AD, Swanson SM, Blanco EJCd. Abstract 4229: Dichamanetin, a C-benzylated flavonoid from Piper sarmentosum inhibits cell growth and induces G1 cell cycle arrest in cancer cells through mitochondrial-mediated apoptosis Cancer Research. 71: 4229-4229. DOI: 10.1158/1538-7445.Am2011-4229  0.35
2011 Shen Q, Matthew S, Wittwer JA, Ren Y, Kinghorn AD, Blanco EJCd, Swanson SM. Abstract 4040: Goyazensolide, a sesquiterpene lactone from Piptocoma rufescens inhibits tumor development in hollow fiber Cancer Research. 71: 4040-4040. DOI: 10.1158/1538-7445.Am2011-4040  0.35
2011 Gupta SV, Sass EJ, Davis ME, Edwards RB, Lozanski G, Heerema NA, Lehman A, Zhang X, Jarjoura D, Byrd JC, Chan KK, Kinghorn AD, Grever M, Phelps MA, Lucas DM. Abstract 1721: Resistance to silvestrol is mediated by MDR1/Pgp over-expression in a lymphoblastic leukemia cell line and is reversible by treatment with rapamycin Cancer Research. 71: 1721-1721. DOI: 10.1158/1538-7445.Am2011-1721  0.302
2011 Pan L, Chin Y, Chai H, Ninh TN, Soejarto DD, Kinghorn AD. Corrigendum to “Bioactivity-guided isolation of cytotoxic constituents of Brucea javanica collected in Vietnam” [Bioorg. Med. Chem. 17 (2009) 2219] Bioorganic & Medicinal Chemistry. 19: 1562. DOI: 10.1016/J.Bmc.2011.01.004  0.304
2010 Pan L, Kardono LB, Riswan S, Chai H, Carcache de Blanco EJ, Pannell CM, Soejarto DD, McCloud TG, Newman DJ, Kinghorn AD. Isolation and characterization of minor analogues of silvestrol and other constituents from a large-scale re-collection of Aglaia foveolata. Journal of Natural Products. 73: 1873-8. PMID 20939540 DOI: 10.1021/Np100503Q  0.514
2010 Quan GH, Oh SR, Kim JH, Lee HK, Kinghorn AD, Chin YW. Xanthone constituents of the fruits of Garcinia mangostana with anticomplement activity. Phytotherapy Research : Ptr. 24: 1575-7. PMID 20878711 DOI: 10.1002/Ptr.3177  0.445
2010 Ren Y, Lantvit DD, Carcache de Blanco EJ, Kardono LB, Riswan S, Chai H, Cottrell CE, Farnsworth NR, Swanson SM, Ding Y, Li XC, Marais JP, Ferreira D, Kinghorn AD. Proteasome-inhibitory and cytotoxic constituents of Garcinia lateriflora: absolute configuration of caged xanthones. Tetrahedron. 66: 5311-5320. PMID 20730041 DOI: 10.1016/J.Tet.2010.05.010  0.48
2010 Balunas MJ, Kinghorn AD. Natural compounds with aromatase inhibitory activity: an update. Planta Medica. 76: 1087-93. PMID 20635310 DOI: 10.1055/S-0030-1250169  0.714
2010 Ren Y, Kardono LB, Riswan S, Chai H, Farnsworth NR, Soejarto DD, Carcache de Blanco EJ, Kinghorn AD. Cytotoxic and NF-kappaB inhibitory constituents of Artocarpus rigida. Journal of Natural Products. 73: 949-55. PMID 20384315 DOI: 10.1021/np1002065  0.393
2010 Lucas DM, Still PC, Pérez LB, Grever MR, Kinghorn AD. Potential of plant-derived natural products in the treatment of leukemia and lymphoma. Current Drug Targets. 11: 812-22. PMID 20370646 DOI: 10.2174/138945010791320809  0.803
2010 Pan L, Chai H, Kinghorn AD. The continuing search for antitumor agents from higher plants. Phytochemistry Letters. 3: 1-8. PMID 20228943 DOI: 10.1016/J.Phytol.2009.11.005  0.372
2010 Pan L, Lantvit DD, Riswan S, Kardono LB, Chai HB, de Blanco EJ, Farnsworth NR, Soejarto DD, Swanson SM, Kinghorn AD. Bioactivity-guided isolation of cytotoxic sesquiterpenes of Rolandra fruticosa. Phytochemistry. 71: 635-40. PMID 20189206 DOI: 10.1016/J.Phytochem.2010.01.012  0.325
2010 Chavez D, Chai H, Chagwedera TE, Gao Q, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. ChemInform Abstract: Novel Stilbenes Isolated from the Root Bark of Ekebergia benguelensis. Cheminform. 32: no-no. DOI: 10.1002/chin.200136227  0.473
2010 Seo E, Chai H, Constant HL, Santisuk T, Reutrakul V, Beecher CWW, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. ChemInform Abstract: Resveratrol Tetramers from Vatica diospyroides. Cheminform. 31: no-no. DOI: 10.1002/chin.200004253  0.345
2009 Balunas MJ, Su B, Riswan S, Fong HH, Brueggemeier RW, Pezzuto JM, Kinghorn AD. Isolation and Characterization of Aromatase Inhibitors from Brassaiopsis glomerulata (Araliaceae). Phytochemistry Letters. 2: 29-33. PMID 20161072 DOI: 10.1016/J.Phytol.2008.10.009  0.744
2009 Kinghorn AD, Carcache de Blanco EJ, Chai HB, Orjala J, Farnsworth NR, Soejarto DD, Oberlies NH, Wani MC, Kroll DJ, Pearce CJ, Swanson SM, Kramer RA, Rose WC, Fairchild CR, Vite GD, et al. Discovery of anticancer agents of diverse natural origin. Pure and Applied Chemistry. Chimie Pure Et Appliquee. 81: 1051-1063. PMID 20046887 DOI: 10.1351/Pac-Con-08-10-16  0.365
2009 Li C, Lee D, Graf TN, Phifer SS, Nakanishi Y, Riswan S, Setyowati FM, Saribi AM, Soejarto DD, Farnsworth NR, Falkinham JO, Kroll DJ, Kinghorn AD, Wani MC, Oberlies NH. Bioactive constituents of the stem bark of Mitrephora glabra. Journal of Natural Products. 72: 1949-53. PMID 19874044 DOI: 10.1021/Np900572G  0.487
2009 Han AR, Kim JA, Lantvit DD, Kardono LB, Riswan S, Chai H, Carcache de Blanco EJ, Farnsworth NR, Swanson SM, Kinghorn AD. Cytotoxic xanthone constituents of the stem bark of Garcinia mangostana (mangosteen). Journal of Natural Products. 72: 2028-31. PMID 19839614 DOI: 10.1021/Np900517H  0.448
2009 Deng Y, Balunas MJ, Kim JA, Lantvit DD, Chin YW, Chai H, Sugiarso S, Kardono LB, Fong HH, Pezzuto JM, Swanson SM, de Blanco EJ, Kinghorn AD. Bioactive 5,6-dihydro-alpha-pyrone derivatives from Hyptis brevipes. Journal of Natural Products. 72: 1165-9. PMID 19422206 DOI: 10.1021/Np9001724  0.76
2009 Ding H, Han C, Guo D, Chin YW, Ding Y, Kinghorn AD, D'Ambrosio SM. Selective induction of apoptosis of human oral cancer cell lines by avocado extracts via a ROS-mediated mechanism. Nutrition and Cancer. 61: 348-56. PMID 19373608 DOI: 10.1080/01635580802567158  0.307
2009 Kinghorn AD, Chin YW, Swanson SM. Discovery of natural product anticancer agents from biodiverse organisms. Current Opinion in Drug Discovery & Development. 12: 189-96. PMID 19333864  0.312
2009 Lucas DM, Edwards RB, Lozanski G, West DA, Shin JD, Vargo MA, Davis ME, Rozewski DM, Johnson AJ, Su BN, Goettl VM, Heerema NA, Lin TS, Lehman A, Zhang X, ... ... Kinghorn AD, et al. The novel plant-derived agent silvestrol has B-cell selective activity in chronic lymphocytic leukemia and acute lymphoblastic leukemia in vitro and in vivo. Blood. 113: 4656-66. PMID 19190247 DOI: 10.1182/Blood-2008-09-175430  0.339
2009 Pan L, Chin YW, Chai HB, Ninh TN, Soejarto DD, Kinghorn AD. Bioactivity-guided isolation of cytotoxic constituents of Brucea javanica collected in Vietnam. Bioorganic & Medicinal Chemistry. 17: 2219-24. PMID 19026551 DOI: 10.1055/S-0028-1083884  0.471
2009 Lucas DM, Sass EJ, Edwards RB, Pan L, Lozanski G, Heerema NA, Byrd JC, Kinghorn AD, Grever MR. Resistance to the Novel Translation Inhibitor Silvestrol Is Mediated by Elevated Mcl-1 Expression. Blood. 114: 1737-1737. DOI: 10.1182/Blood.V114.22.1737.1737  0.319
2009 Pan L, Sinden MR, Kennedy AH, Chai H, Watson LE, Graham TL, Kinghorn AD. Bioactive constituents of Helianthus tuberosus (Jerusalem artichoke) Phytochemistry Letters. 2: 15-18. DOI: 10.1016/J.Phytol.2008.10.003  0.468
2008 Balunas MJ, Su B, Brueggemeier RW, Kinghorn AD. Natural products as aromatase inhibitors. Anti-Cancer Agents in Medicinal Chemistry. 8: 646-82. PMID 18690828 DOI: 10.2174/187152008785133092  0.704
2008 Chin YW, Chai HB, Keller WJ, Kinghorn AD. Lignans and other constituents of the fruits of Euterpe oleracea (Acai) with antioxidant and cytoprotective activities. Journal of Agricultural and Food Chemistry. 56: 7759-64. PMID 18656934 DOI: 10.1021/Jf801792N  0.43
2008 Balunas MJ, Su B, Brueggemeier RW, Kinghorn AD. Xanthones from the botanical dietary supplement mangosteen (Garcinia mangostana) with aromatase inhibitory activity. Journal of Natural Products. 71: 1161-6. PMID 18558747 DOI: 10.1021/Np8000255  0.705
2008 Tomosaka H, Chin YW, Salim AA, Keller WJ, Chai H, Kinghorn AD. Antioxidant and cytoprotective compounds from Berberis vulgaris (barberry). Phytotherapy Research : Ptr. 22: 979-81. PMID 18389483 DOI: 10.1002/Ptr.2443  0.42
2008 Chin YW, Salim AA, Su BN, Mi Q, Chai HB, Riswan S, Kardono LB, Ruskandi A, Farnsworth NR, Swanson SM, Kinghorn AD. Potential anticancer activity of naturally occurring and semisynthetic derivatives of aculeatins A and B from Amomum aculeatum. Journal of Natural Products. 71: 390-5. PMID 18260638 DOI: 10.1021/Np070584J  0.446
2008 Chin YW, Jung HA, Chai H, Keller WJ, Kinghorn AD. Xanthones with quinone reductase-inducing activity from the fruits of Garcinia mangostana (Mangosteen). Phytochemistry. 69: 754-8. PMID 17991497 DOI: 10.1016/J.Phytochem.2007.09.023  0.499
2008 Rivero-Cruz JF, Zhu M, Kinghorn AD, Wu CD. Antimicrobial constituents of Thompson seedless raisins (Vitis vinifera) against selected oral pathogens Phytochemistry Letters. 1: 151-154. DOI: 10.1016/J.Phytol.2008.07.007  0.413
2007 Salim AA, Chai HB, Rachman I, Riswan S, Kardono LB, Farnsworth NR, Carcache-Blanco EJ, Kinghorn AD. Constituents of the Leaves and Stem Bark of Aglaia foveolata. Tetrahedron. 63: 7926-7934. PMID 18698338 DOI: 10.1016/J.Tet.2007.05.074  0.517
2007 Salim AA, Su BN, Chai HB, Riswan S, Kardono LB, Ruskandi A, Farnsworth NR, Swanson SM, Kinghorn AD. Dioxadispiroketal Compounds and a Potential Acyclic Precursor from Amomum aculeatum. Tetrahedron Letters. 48: 1849-1853. PMID 18320008 DOI: 10.1016/J.Tetlet.2007.01.017  0.494
2007 Deng Y, Chin YW, Chai H, Keller WJ, Kinghorn AD. Anthraquinones with quinone reductase-inducing activity and benzophenones from Morinda citrifolia (noni) roots. Journal of Natural Products. 70: 2049-52. PMID 18076142 DOI: 10.1021/Np070501Z  0.505
2007 Chin YW, Kinghorn AD, Patil PN. Evaluation of the cholinergic and adrenergic effects of two tropane alkaloids from Erythroxylum pervillei. Phytotherapy Research : Ptr. 21: 1002-5. PMID 17602438 DOI: 10.1002/Ptr.2155  0.325
2007 Ding H, Chin YW, Kinghorn AD, D'Ambrosio SM. Chemopreventive characteristics of avocado fruit. Seminars in Cancer Biology. 17: 386-94. PMID 17582784 DOI: 10.1016/J.Semcancer.2007.04.003  0.324
2007 Phifer SS, Lee D, Seo EK, Kim NC, Graf TN, Kroll DJ, Navarro HA, Izydore RA, Jiménez F, Garcia R, Rose WC, Fairchild CR, Wild R, Soejarto DD, Farnsworth NR, ... Kinghorn AD, et al. Alvaradoins E-N, antitumor and cytotoxic anthracenone C-glycosides from the leaves of Alvaradoa haitiensis. Journal of Natural Products. 70: 954-61. PMID 17552563 DOI: 10.1021/Np070005A  0.452
2007 Murillo G, Hirschelman WH, Ito A, Moriarty RM, Kinghorn AD, Pezzuto JM, Mehta RG. Zapotin, a phytochemical present in a Mexican fruit, prevents colon carcinogenesis. Nutrition and Cancer. 57: 28-37. PMID 17516860 DOI: 10.1080/01635580701268097  0.335
2007 Chin YW, Jung HA, Liu Y, Su BN, Castoro JA, Keller WJ, Pereira MA, Kinghorn AD. Anti-oxidant constituents of the roots and stolons of licorice (Glycyrrhiza glabra). Journal of Agricultural and Food Chemistry. 55: 4691-7. PMID 17516657 DOI: 10.1021/Jf0703553  0.44
2007 Jones WP, Lobo-Echeverri T, Mi Q, Chai HB, Soejarto DD, Cordell GA, Swanson SM, Kinghorn AD. Cytotoxic constituents from the fruiting branches of Callicarpa americana collected in southern Florida. Journal of Natural Products. 70: 372-7. PMID 17279798 DOI: 10.1021/Np060534Z  0.617
2007 Lucas DM, Edwards RB, Lay MDD, West DA, Lozanski G, Johnson AJ, Salim AA, Lin TS, Byrd JC, Kinghorn AD, Grever MR. The plant-derived agent silvestrol has B-Cell selective activity in vitro in chronic lymphocytic leukemia patient cells and in vivo in the Tcl-1 mouse model of CLL Blood. 110: 3123-3123. DOI: 10.1182/Blood.V110.11.3123.3123  0.334
2007 Kim S, Chin YW, Su BN, Riswan S, Kardono LBS, Afriastini JJ, Chai H, Farnsworth NR, Cordell GA, Swanson SM, Kinghorn AD. Erratum: Cytotoxic flavaglines and bisamides from Aglaia edulis (Journal of Natural Products (2006) 69 (1770-1771)) Journal of Natural Products. 70. DOI: 10.1021/Np070076+  0.472
2006 Balunas MJ, Jones WP, Chin YW, Mi Q, Farnsworth NR, Soejarto DD, Cordell GA, Swanson SM, Pezzuto JM, Chai HB, Kinghorn AD. Relationships between inhibitory activity against a cancer cell line panel, profiles of plants collected, and compound classes isolated in an anticancer drug discovery project. Chemistry & Biodiversity. 3: 897-915. PMID 17193321 DOI: 10.1002/Cbdv.200690092  0.773
2006 Kim S, Chin YW, Su BN, Riswan S, Kardono LB, Afriastini JJ, Chai H, Farnsworth NR, Cordell GA, Swanson SM, Kinghorn AD. Cytotoxic flavaglines and bisamides from Aglaia edulis. Journal of Natural Products. 69: 1769-75. PMID 17190457 DOI: 10.1021/Np060428X  0.595
2006 Chin YW, Mdee LK, Mbwambo ZH, Mi Q, Chai HB, Cragg GM, Swanson SM, Kinghorn AD. Prenylated flavonoids from the root bark of Berchemia discolor, a Tanzanian medicinal plant. Journal of Natural Products. 69: 1649-52. PMID 17125241 DOI: 10.1021/Np060418W  0.502
2006 Kim S, Salim AA, Swanson SM, Kinghorn AD. Potential of cyclopenta[b]benzofurans from Aglaia species in cancer chemotherapy. Anti-Cancer Agents in Medicinal Chemistry. 6: 319-45. PMID 16842234 DOI: 10.2174/187152006777698123  0.417
2006 Chin YW, Balunas MJ, Chai HB, Kinghorn AD. Drug discovery from natural sources. The Aaps Journal. 8: E239-53. PMID 16796374 DOI: 10.1007/Bf02854894  0.709
2006 Chin YW, Jones WP, Mi Q, Rachman I, Riswan S, Kardono LB, Chai HB, Farnsworth NR, Cordell GA, Swanson SM, Cassady JM, Kinghorn AD. Cytotoxic clerodane diterpenoids from the leaves of Premna tomentosa. Phytochemistry. 67: 1243-8. PMID 16777158 DOI: 10.1016/J.Phytochem.2006.04.015  0.555
2006 Balunas MJ, Su B, Landini S, Brueggemeier RW, Kinghorn AD. Interference by naturally occurring fatty acids in a noncellular enzyme-based aromatase bioassay. Journal of Natural Products. 69: 700-3. PMID 16643058 DOI: 10.1021/Np050513P  0.698
2006 Mi Q, Su BN, Chai H, Cordell GA, Farnsworth NR, Kinghorn AD, Swanson SM. Rocaglaol induces apoptosis and cell cycle arrest in LNCaP cells. Anticancer Research. 26: 947-52. PMID 16619491  0.388
2006 Chin YW, Jones WP, Waybright TJ, McCloud TG, Rasoanaivo P, Cragg GM, Cassady JM, Kinghorn AD. Tropane aromatic ester alkaloids from a large-scale re-collection of Erythroxylum pervillei stem bark obtained in Madagascar Journal of Natural Products. 69: 414-417. PMID 16562848 DOI: 10.1021/Np050366V  0.313
2006 Fang L, Ito A, Chai HB, Mi Q, Jones WP, Madulid DR, Oliveros MB, Gao Q, Orjala J, Farnsworth NR, Soejarto DD, Cordell GA, Swanson SM, Pezzuto JM, Kinghorn AD. Cytotoxic constituents from the stem bark of Dichapetalum gelonioides collected in the Philippines. Journal of Natural Products. 69: 332-7. PMID 16562829 DOI: 10.1021/Np058083Q  0.63
2006 Fong HHS, Cordell GA, Kinghorn AD. Special issue in honor of Norman R. Farnsworth Journal of Natural Products. 69: 311-313. PMID 16562824 DOI: 10.1021/np068000l  0.324
2006 Jung HA, Su BN, Keller WJ, Mehta RG, Kinghorn AD. Antioxidant xanthones from the pericarp of Garcinia mangostana (Mangosteen) Journal of Agricultural and Food Chemistry. 54: 2077-2082. PMID 16536578 DOI: 10.1021/Jf052649Z  0.474
2006 Jang DS, Su BN, Pawlus AD, Kang YH, Kardono LB, Riswan S, Afriastini JJ, Fong HH, Pezzuto JM, Kinghorn AD. Beccaridiol, an unusual 28-nortriterpenoid from the leaves of Diplectria beccariana. Phytochemistry. 67: 1832-7. PMID 16426647 DOI: 10.1016/J.Phytochem.2005.11.026  0.471
2006 Chin YW, Jones WP, Rachman I, Riswan S, Kardono LB, Chai HB, Farnsworth NR, Cordell GA, Swanson SM, Cassady JM, Kinghorn AD. Cytotoxic lignans from the stems of Helicteres hirsuta collected in Indonesia. Phytotherapy Research : Ptr. 20: 62-5. PMID 16397845 DOI: 10.1002/Ptr.1806  0.547
2006 Su BN, Chai H, Mi Q, Riswan S, Kardono LB, Afriastini JJ, Santarsiero BD, Mesecar AD, Farnsworth NR, Cordell GA, Swanson SM, Kinghorn AD. Activity-guided isolation of cytotoxic constituents from the bark of Aglaia crassinervia collected in Indonesia. Bioorganic & Medicinal Chemistry. 14: 960-72. PMID 16216518 DOI: 10.1016/J.Bmc.2005.09.012  0.598
2006 Edwards RB, Lucas DM, Lozanski G, Johnson AJ, Su B, Lin TS, Byrd JC, Kinghorn AD, Grever MR. Silvestrol, a Rocaglate Derivative from the Indonesian Plant Aglaia foveolata , Has Significant Bcl-2- and p53-Independent Anti-Tumor Activity against Chronic Lymphocytic Leukemia Cells. Blood. 108: 2600-2600. DOI: 10.1182/Blood.V108.11.2600.2600  0.369
2005 Pawlus AD, Su BN, Keller WJ, Kinghorn AD. An anthraquinone with potent quinone reductase-inducing activity and other constituents of the fruits of Morinda citrifolia (noni). Journal of Natural Products. 68: 1720-2. PMID 16378361 DOI: 10.1021/Np050383K  0.502
2005 Li C, Lee D, Graf TN, Phifer SS, Nakanishi Y, Burgess JP, Riswan S, Setyowati FM, Saribi AM, Soejarto DD, Farnsworth NR, Falkinham JO, Kroll DJ, Kinghorn AD, Wani MC, et al. A hexacyclic ent-trachylobane diterpenoid possessing an oxetane ring from Mitrephora glabra. Organic Letters. 7: 5709-12. PMID 16321028 DOI: 10.1021/Ol052498L  0.461
2005 Balunas MJ, Kinghorn AD. Drug discovery from medicinal plants Life Sciences. 78: 431-441. PMID 16198377 DOI: 10.1016/J.Lfs.2005.09.012  0.703
2005 Lee D, Li C, Graf TN, Vigo JS, Graham JG, Cabieses F, Farnsworth NR, Cordell GA, Kinghorn AD, Kroll DJ, Wani MC, Oberlies NH. Diterpene glycosides from Egletes viscosa. Planta Medica. 71: 792-4. PMID 16142652 DOI: 10.1055/S-2005-871227  0.555
2005 Jones WP, Lobo-Echeverri T, Mi Q, Chai H, Lee D, Soejarto DD, Cordell GA, Pezzuto JM, Swanson SM, Kinghorn AD. Antitumour activity of 3-chlorodeoxylapachol, a naphthoquinone from Avicennia germinans collected from an experimental plot in southern Florida. The Journal of Pharmacy and Pharmacology. 57: 1101-8. PMID 16105231 DOI: 10.1211/Jpp.57.9.0005  0.592
2005 Jang DS, Su BN, Pawlus AD, Jones WP, Kleps RA, Bunyapraphatsara N, Fong HH, Pezzuto JM, Kinghorn AD. Limnophilaspiroketone, a highly oxygenated phenolic derivative from Limnophila geoffrayi. Journal of Natural Products. 68: 1134-6. PMID 16038568 DOI: 10.1021/Np050132B  0.359
2005 Mi Q, Lantvit D, Reyes-Lim E, Chai H, Phifer SS, Wani MC, Wall ME, Tan GT, Cordell GA, Farnsworth NR, Kinghorn AD, Pezzuto JM. Apoptotic anticancer effect of alvaradoin E isolated from Alvaradoa haitiensis. Anticancer Research. 25: 779-87. PMID 15868909  0.471
2005 Rivero-Cruz JF, Lezutekong R, Lobo-Echeverri T, Ito A, Mi Q, Chai HB, Soejarto DD, Cordell GA, Pezzuto JM, Swanson SM, Morelli I, Kinghorn AD. Cytotoxic constituents of the twigs of Simarouba glauca collected from a plot in Southern Florida. Phytotherapy Research : Ptr. 19: 136-40. PMID 15852485 DOI: 10.1002/Ptr.1642  0.573
2005 Su BN, Pawlus AD, Jung HA, Keller WJ, McLaughlin JL, Kinghorn AD. Chemical constituents of the fruits of Morinda citrifolia (Noni) and their antioxidant activity. Journal of Natural Products. 68: 592-5. PMID 15844957 DOI: 10.1021/Np0495985  0.383
2005 Lobo-Echeverri T, Rivero-Cruz JF, Su BN, Chai HB, Cordell GA, Pezzuto JM, Swanson SM, Soejarto DD, Kinghorn AD. Constituents of the leaves and twigs of Calyptranthes pallens collected from an experimental plot in Southern Florida. Journal of Natural Products. 68: 577-80. PMID 15844953 DOI: 10.1021/Np0496688  0.578
2005 Gu J, Kinghorn AD. Bioactive Constituents of the Genus Hernandia Studies in Natural Products Chemistry. 30: 559-602. DOI: 10.1016/S1572-5995(05)80042-0  0.332
2005 Kim S, Su BN, Riswan S, Kardono LBS, Afriastini JJ, Gallucci JC, Chai H, Farnsworth NR, Cordell GA, Swanson SM, Kinghorn AD. Edulisones a and B, two epimeric benzo[b]oxepine derivatives from the bark of Aglaia edulis Tetrahedron Letters. 46: 9021-9024. DOI: 10.1016/J.Tetlet.2005.10.107  0.498
2004 Su BN, Hwang BY, Chai H, Carcache-Blanco EJ, Kardono LB, Afriastini JJ, Riswan S, Wild R, Laing N, Farnsworth NR, Cordell GA, Swanson SM, Kinghorn AD. Activity-guided fractionation of the leaves of Ormosia sumatrana using a proteasome inhibition assay. Journal of Natural Products. 67: 1911-4. PMID 15568789 DOI: 10.1021/Np040134G  0.535
2004 Su BN, Jones WP, Cuendet M, Kardono LB, Ismail R, Riswan S, Fong HH, Farnsworth NR, Pezzuto JM, Kinghorn AD. Constituents of the stems of Macrococculus pomiferus and their inhibitory activities against cyclooxygenases-1 and -2. Phytochemistry. 65: 2861-6. PMID 15501253 DOI: 10.1016/J.Phytochem.2004.08.007  0.437
2004 Jang DS, Cuendet M, Su BN, Totura S, Riswan S, Fong HHS, Pezzuto JM, Kinghorn AD. Constituents of the seeds of Hernandia ovigera with inhibitory activity against cyclooxygenase-2 Planta Medica. 70: 893-896. PMID 15490314 DOI: 10.1055/S-2004-832612  0.388
2004 Kinghorn AD, Su BN, Jang DS, Chang LC, Lee D, Gu JQ, Carcache-Blanco EJ, Pawlus AD, Lee SK, Park EJ, Cuendet M, Gills JJ, Bhat K, Park HS, Mata-Greenwood E, et al. Natural inhibitors of carcinogenesis. Planta Medica. 70: 691-705. PMID 15326546 DOI: 10.1055/S-2004-827198  0.511
2004 Gu JQ, Graf TN, Lee D, Chai HB, Mi Q, Kardono LB, Setyowati FM, Ismail R, Riswan S, Farnsworth NR, Cordell GA, Pezzuto JM, Swanson SM, Kroll DJ, Falkinham JO, ... ... Kinghorn AD, et al. Cytotoxic and antimicrobial constituents of the bark of Diospyros maritima collected in two geographical locations in Indonesia. Journal of Natural Products. 67: 1156-61. PMID 15270571 DOI: 10.1021/Np040027M  0.581
2004 Braca A, Armenise A, Morelli I, Mendez J, Mi Q, Chai HB, Swanson SM, Kinghorn AD, De Tommasi N. Structure of kaurane-type diterpenes from Parinari sprucei and their potential anticancer activity. Planta Medica. 70: 540-50. PMID 15229806 DOI: 10.1055/S-2004-827155  0.488
2004 Hwang BY, Su BN, Chai H, Mi Q, Kardono LB, Afriastini JJ, Riswan S, Santarsiero BD, Mesecar AD, Wild R, Fairchild CR, Vite GD, Rose WC, Farnsworth NR, Cordell GA, ... ... Kinghorn AD, et al. Silvestrol and episilvestrol, potential anticancer rocaglate derivatives from Aglaia silvestris. The Journal of Organic Chemistry. 69: 3350-8. PMID 15132542 DOI: 10.1021/Jo040120F  0.572
2004 Jang DS, Cuendet M, Fong HHS, Pezzuto JM, Kinghorn AD. Constituents of Asparagus officinalis Evaluated for Inhibitory Activity against Cyclooxygenase-2 Journal of Agricultural and Food Chemistry. 52: 2218-2222. PMID 15080623 DOI: 10.1021/Jf0305229  0.452
2004 Diaz F, Chai HB, Mi Q, Su BN, Vigo JS, Graham JG, Cabieses F, Farnsworth NR, Cordell GA, Pezzuto JM, Swanson SM, Kinghorn AD. Anthrone and oxanthrone C-glycosides from Picramnia latifolia collected in Peru. Journal of Natural Products. 67: 352-6. PMID 15043409 DOI: 10.1021/Np030479J  0.608
2004 Rivero-Cruz JF, Chai HB, Kardono LB, Setyowati FM, Afriatini JJ, Riswan S, Farnsworth NR, Cordell GA, Pezzuto JM, Swanson SM, Kinghorn AD. Cytotoxic constituents of the twigs and leaves of Aglaia rubiginosa. Journal of Natural Products. 67: 343-7. PMID 15043407 DOI: 10.1021/Np0304417  0.596
2004 Jang DS, Park EJ, Kang YH, Vigo JS, Graham JG, Cabieses F, Fong HH, Pezzuto JM, Kinghorn AD. Phenolic compounds obtained from stems of Couepia ulei with the potential to induce quinone reductase. Archives of Pharmacal Research. 27: 169-72. PMID 15022717 DOI: 10.1007/Bf02980101  0.493
2004 Ito A, Chai HB, Kardono LB, Setowati FM, Afriastini JJ, Riswan S, Farnsworth NR, Cordell GA, Pezzuto JM, Swanson SM, Kinghorn AD. Saponins from the bark of Nephelium maingayi. Journal of Natural Products. 67: 201-5. PMID 14987059 DOI: 10.1021/Np030389E  0.629
2004 Jang DS, Cuendet M, Pawlus AD, Kardono LB, Kawanishi K, Farnsworth NR, Fong HH, Pezzuto JM, Kinghorn AD. Potential cancer chemopreventive constituents of the leaves of Macaranga triloba. Phytochemistry. 65: 345-50. PMID 14751306 DOI: 10.1016/J.Phytochem.2003.10.026  0.368
2004 Su B, Gu J, Kang Y, Park E, Pezzuto J, Kinghorn A. Induction of the Phase II Enzyme, Quinone Reductase, by Withanolides and Norwithanolides from Solanaceous Species Mini-Reviews in Organic Chemistry. 1: 115-123. DOI: 10.2174/1570193043488926  0.377
2004 Shin YG, Udeani GO, Kosmeder JW, Zhao GM, Dagar S, Onyuksel H, Moriarty RM, Cordell GA, Moon RC, Kinghorn AD, Pezzuto JM. Identification of Degradation Product of Deguelin and Its Stability Using Liquid Chromatography and Electrospray/Mass Spectrometry Journal of Liquid Chromatography and Related Technologies. 27: 1057-1069. DOI: 10.1081/Jlc-120030178  0.453
2004 Hwang BY, Su BN, Chai H, Mi Q, Kardono LBS, Afriastini JJ, Riswan S, Santarsiero B, Mesecar AD, Wild R, Fairchild CR, Vite GD, Rose WC, Farnsworth NR, Cordell GA, ... ... Kinghorn AD, et al. Erratum: Silvestrol and episilvestrol, potential anticancer rocaglate derivatives from Aglaia silvestris (Journal of Organic Chemistry (2004) 69 (3350-3357)) Journal of Organic Chemistry. 69. DOI: 10.1021/Jo040008H  0.452
2003 Abo KA, Kinghorn AD. Isolation of an anti-tumour terpenoid from stem bark of Spondianthus preussii var. preussii Engl. African Journal of Medicine and Medical Sciences. 32: 179-82. PMID 15032466  0.361
2003 Carcache-Blanco EJ, Kang YH, Park EJ, Su BN, Kardono LBS, Riswan S, Fong HHS, Pezzuto JM, Kinghorn AD. Constituents of the stem bark of Pongamia pinnata with the potential to induce quinone reductase Journal of Natural Products. 66: 1197-1202. PMID 14510596 DOI: 10.1021/Np030207G  0.49
2003 Jang DS, Park EJ, Kang YH, Hawthorne ME, Vigo JS, Graham JG, Cabieses F, Fong HH, Mehta RG, Pezzuto JM, Kinghorn AD. Potential cncer chemopreventive flavonoids from the stems of Tephrosia toxicaria. Journal of Natural Products. 66: 1166-70. PMID 14510590 DOI: 10.1021/Np0302100  0.475
2003 Jang DS, Park EJ, Kang YH, Su BN, Hawthorne ME, Vigo JS, Graham JG, Cabieses F, Fong HH, Mehta RG, Pezzuto JM, Kinghorn AD. Compounds obtained from sida acuta with the potential to induce quinone reductase and to inhibit 7,12-dimethylbenz[a]anthracene-induced preneoplastic lesions in a mouse mammary organ culture model. Archives of Pharmacal Research. 26: 585-90. PMID 12967190 DOI: 10.1007/Bf02976704  0.465
2003 Su BN, Kang YH, Pinos RE, Santarsiero BD, Mesecar AD, Soejarto DD, Fong HH, Pezzuto JM, Kinghorn AD. Isolation and absolute stereochemistry of coussaric acid, a new bioactive triterpenoid from the stems of Coussarea brevicaulis. Phytochemistry. 64: 293-302. PMID 12946428 DOI: 10.1016/S0031-9422(03)00268-1  0.418
2003 Su BN, Park EJ, Nikolic D, Schunke Vigo J, Graham JG, Cabieses F, van Breemen RB, Fong HH, Farnsworth NR, Pezzuto JM, Kinghorn AD. Isolation and characterization of miscellaneous secondary metabolites of Deprea subtriflora. Journal of Natural Products. 66: 1089-93. PMID 12932130 DOI: 10.1021/Np030081N  0.435
2003 Hwang BY, Roberts SK, Chadwick LR, Wu CD, Kinghorn AD. Antimicrobial constituents from goldenseal (the Rhizomes of Hydrastis canadensis) against selected oral pathogens. Planta Medica. 69: 623-7. PMID 12898417 DOI: 10.1055/S-2003-41115  0.415
2003 Díaz F, Chávez D, Lee D, Mi Q, Chai HB, Tan GT, Kardono LB, Riswan S, Fairchild CR, Wild R, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Cytotoxic flavone analogues of vitexicarpin, a constituent of the leaves of Vitex negundo. Journal of Natural Products. 66: 865-7. PMID 12828478 DOI: 10.1021/Np0300784  0.622
2003 Jang DS, Park EJ, Hawthorne ME, Vigo JS, Graham JG, Cabieses F, Santarsiero BD, Mesecar AD, Fong HH, Mehta RG, Pezzuto JM, Kinghorn AD. Potential cancer chemopreventive constituents of the seeds of Dipteryx odorata (tonka bean). Journal of Natural Products. 66: 583-7. PMID 12762787 DOI: 10.1021/Np020522N  0.503
2003 Fang L, Chai HB, Castillo JJ, Soejarto DD, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Cytotoxic constituents of Brachistus stramoniifolius. Phytotherapy Research : Ptr. 17: 520-3. PMID 12748990 DOI: 10.1002/Ptr.1315  0.626
2003 Su BN, Jung Park E, Vigo JS, Graham JG, Cabieses F, Fong HH, Pezzuto JM, Kinghorn AD. Activity-guided isolation of the chemical constituents of Muntingia calabura using a quinone reductase induction assay. Phytochemistry. 63: 335-41. PMID 12737982 DOI: 10.1016/S0031-9422(03)00112-2  0.476
2003 Gu JQ, Li W, Kang YH, Su BN, Fong HHS, Van Breemen RB, Pezzuto JM, Kinghorn AD. Minor withanolides from Physalis philadelphica: Structures, quinone reductase induction activities, and liquid chromatography (LC)-MS-MS investigation as artifacts Chemical and Pharmaceutical Bulletin. 51: 530-539. PMID 12736452 DOI: 10.1248/Cpb.51.530  0.353
2003 Seo EK, Lee D, Shin YG, Chai HB, Navarro HA, Kardono LB, Rahman I, Cordell GA, Farnsworth NR, Pezzuto JM, Kinghorn AD, Wani MC, Wall ME. Bioactive prenylated flavonoids from the stem bark of Artocarpus kemando. Archives of Pharmacal Research. 26: 124-7. PMID 12643587 DOI: 10.1007/Bf02976656  0.557
2003 Su BN, Park EJ, Nikolic D, Santarsiero BD, Mesecar AD, Vigo JS, Graham JG, Cabieses F, van Breemen RB, Fong HH, Farnsworth NR, Pezzuto JM, Kinghorn AD. Activity-guided isolation of novel norwithanolides from depreasubtriflora with potential cancer chemopreventive activity. The Journal of Organic Chemistry. 68: 2350-61. PMID 12636402 DOI: 10.1021/Jo020542U  0.482
2003 Hwang BY, Chai HB, Kardono LB, Riswan S, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Cytotoxic triterpenes from the twigs of Celtis philippinensis. Phytochemistry. 62: 197-201. PMID 12482456 DOI: 10.1016/S0031-9422(02)00520-4  0.51
2003 Kinghorn AD, Su BN, Lee D, Gu JQ, Pezzuto JM. Cancer chemopreventive agents discovered by activity-guided fractionation: An update Current Organic Chemistry. 7: 213-226. DOI: 10.2174/1385272033373003  0.365
2003 Kinghorn AD, Farnsworth NR, Soejarto DD, Cordell GA, Swanson SM, Pezzuto JM, Wani MC, Wall ME, Oberlies NH, Kroll DJ, Kramer RA, Rose WC, Vite GD, Fairchild CR, Peterson RW, et al. Novel strategies for the discovery of plant-derived anticancer agents Pharmaceutical Biology. 41: 53-67. DOI: 10.1351/Pac199971091611  0.508
2003 Lee D, Kinghorn AD. Bioactive compounds from the genus broussonetia Studies in Natural Products Chemistry. 28: 3-33. DOI: 10.1016/S1572-5995(03)80137-0  0.397
2003 Su BN, Cuendet M, Nikolic D, Kristinsson H, Ingólfsdóttir K, Van Breemen RB, Fong HHS, Pezzuto JM, Kinghorn AD. NMR study of fumarprotocetraric acid, a complex lichen depsidone derivative from Cladonia furcata Magnetic Resonance in Chemistry. 41: 391-394. DOI: 10.1002/Mrc.1181  0.306
2002 Kim NC, Kinghorn AD. Highly sweet compounds of plant origin Archives of Pharmacal Research. 25: 725-746. PMID 12510821 DOI: 10.1007/Bf02976987  0.472
2002 Su BN, Cuendet M, Farnsworth NR, Fong HH, Pezzuto JM, Kinghorn AD. Activity-guided fractionation of the seeds of Ziziphus jujuba using a cyclooxygenase-2 inhibitory assay. Planta Medica. 68: 1125-8. PMID 12494342 DOI: 10.1055/S-2002-36354  0.348
2002 Jang DS, Cuendet M, Hawthorne ME, Kardono LBS, Kawanishi K, Fonga HHS, Mehta RG, Pezzuto JM, Kinghorn AD. Prenylated flavonoids of the leaves of Macaranga conifera with inhibitory activity against cyclooxygenase-2 Phytochemistry. 61: 867-872. PMID 12453581 DOI: 10.1016/S0031-9422(02)00378-3  0.495
2002 Gu JQ, Park EJ, Vigo JS, Graham JG, Fong HH, Pezzuto JM, Kinghorn AD. Activity-guided isolation of constituents of Renealmia nicolaioides with the potential to induce the phase II enzyme quinone reductase. Journal of Natural Products. 65: 1616-20. PMID 12444686 DOI: 10.1021/Np020249P  0.441
2002 Jang DS, Park EJ, Hawthorne ME, Vigo JS, Graham JG, Cabieses F, Santarsiero BD, Mesecar AD, Fong HH, Mehta RG, Pezzuto JM, Kinghorn AD. Constituents of Musa x paradisiaca cultivar with the potential to induce the phase II enzyme, quinone reductase. Journal of Agricultural and Food Chemistry. 50: 6330-4. PMID 12381112 DOI: 10.1021/Jf0206670  0.432
2002 Su BN, Park EJ, Mbwambo ZH, Santarsiero BD, Mesecar AD, Fong HH, Pezzuto JM, Kinghorn AD. New chemical constituents of Euphorbia quinquecostata and absolute configuration assignment by a convenient Mosher ester procedure carried out in NMR tubes. Journal of Natural Products. 65: 1278-82. PMID 12350147 DOI: 10.1021/Np0202475  0.457
2002 Su BN, Chang LC, Park EJ, Cuendet M, Santarsiero BD, Mesecar AD, Mehta RG, Fong HH, Pezzuto JM, Kinghorn AD. Bioactive constituents of the seeds of Brucea javanica. Planta Medica. 68: 730-3. PMID 12221597 DOI: 10.1055/S-2002-33798  0.451
2002 Ito A, Chai HB, Lee D, Kardono LB, Riswan S, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Ellagic acid derivatives and cytotoxic cucurbitacins from Elaeocarpus mastersii. Phytochemistry. 61: 171-4. PMID 12169311 DOI: 10.1016/S0031-9422(02)00232-7  0.519
2002 Mi Q, Cui B, Chávez D, Chai H, Zhu H, Cordell GA, Hedayat S, Kinghorn AD, Pezzuto JM. Characterization of tropane alkaloid aromatic esters that reverse the multidrug-resistance phenotype. Anticancer Research. 22: 1385-97. PMID 12168815  0.401
2002 Kim NC, Kim DS, Kinghorn AD. New triterpenoids from the leaves of Abrus precatorius. Natural Product Letters. 16: 261-6. PMID 12168762 DOI: 10.1080/10575630290020596  0.31
2002 Gu JQ, Park EJ, Totura S, Riswan S, Fong HH, Pezzuto JM, Kinghorn AD. Constituents of the twigs of Hernandia ovigera that inhibit the transformation of JB6 murine epidermal cells. Journal of Natural Products. 65: 1065-8. PMID 12141878 DOI: 10.1021/Np020042W  0.388
2002 Blatt CT, Chávez D, Chai H, Graham JG, Cabieses F, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Cytotoxic flavonoids from the stem bark of Lonchocarpus aff. fluvialis. Phytotherapy Research : Ptr. 16: 320-5. PMID 12112286 DOI: 10.1002/Ptr.889  0.615
2002 Mi Q, Cui B, Silva GL, Lantvit D, Lim E, Chai H, Hollingshead MG, Mayo JG, Kinghorn AD, Pezzuto JM. Pervilleines B and C, new tropane alkaloid aromatic esters that reverse the multidrug-resistance in the hollow fiber assay. Cancer Letters. 184: 13-20. PMID 12104043 DOI: 10.1016/S0304-3835(02)00202-1  0.359
2002 Mi Q, Lantvit D, Reyes-Lim E, Chai H, Zhao W, Lee IS, Peraza-Sánchez S, Ngassapa O, Kardono LB, Riswan S, Hollingshead MG, Mayo JG, Farnsworth NR, Cordell GA, Kinghorn AD, et al. Evaluation of the potential cancer chemotherapeutic efficacy of natural product isolates employing in vivo hollow fiber tests. Journal of Natural Products. 65: 842-50. PMID 12088425 DOI: 10.1021/Np010322W  0.465
2002 Misico RI, Song LL, Veleiro AS, Cirigliano AM, Tettamanzi MC, Burton G, Bonetto GM, Nicotra VE, Silva GL, Gil RR, Oberti JC, Kinghorn AD, Pezzuto JM. Induction of quinone reductase by withanolides. Journal of Natural Products. 65: 677-80. PMID 12027740 DOI: 10.1021/Np0106337  0.748
2002 Chávez D, Cui B, Chai HB, García R, Mejía M, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Reversal of multidrug resistance by tropane alkaloids from the stems of Erythroxylum rotundifolium. Journal of Natural Products. 65: 606-10. PMID 11975514 DOI: 10.1021/Np0104774  0.484
2002 Gu JQ, Gills JJ, Park EJ, Mata-Greenwood E, Hawthorne ME, Axelrod F, Chavez PI, Fong HH, Mehta RG, Pezzuto JM, Kinghorn AD. Sesquiterpenoids from Tithonia diversifolia with potential cancer chemopreventive activity. Journal of Natural Products. 65: 532-6. PMID 11975495 DOI: 10.1021/Np010545M  0.368
2002 Seo EK, Kim NC, Wani MC, Wall ME, Navarro HA, Burgess JP, Kawanishi K, Kardono LB, Riswan S, Rose WC, Fairchild CR, Farnsworth NR, Kinghorn AD. Cytotoxic prenylated xanthones and the unusual compounds anthraquinobenzophenones from Cratoxylum sumatranum. Journal of Natural Products. 65: 299-305. PMID 11908969 DOI: 10.1021/Np010395F  0.498
2002 Peraza-Sánchez SR, Chai HB, Shin YG, Santisuk T, Reutrakul V, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Constituents of the leaves and twigs of Ficus hispida. Planta Medica. 68: 186-8. PMID 11859479 DOI: 10.1055/S-2002-20257  0.57
2002 Su BN, Cuendet M, Hawthorne ME, Kardono LB, Riswan S, Fong HH, Mehta RG, Pezzuto JM, Kinghorn AD. Constituents of the bark and twigs of Artocarpus dadah with cyclooxygenase inhibitory activity. Journal of Natural Products. 65: 163-9. PMID 11858749 DOI: 10.1021/Np010451C  0.464
2002 Oberlies NH, Burgess JP, Navarro HA, Pinos RE, Fairchild CR, Peterson RW, Soejarto DD, Farnsworth NR, Kinghorn AD, Wani MC, Wall ME. Novel bioactive clerodane diterpenoids from the leaves and twigs of Casearia sylvestris. Journal of Natural Products. 65: 95-9. PMID 11858737 DOI: 10.1021/Np010459M  0.355
2002 Lee D, Park EJ, Cuendet M, Axelrod F, Chavez PI, Fong HH, Pezzuto JM, Kinghorn AD. Cyclooxygenase-inhibitory and antioxidant constituents of the aerial parts of Antirhea acutata. Bioorganic & Medicinal Chemistry Letters. 11: 1565-8. PMID 11412982 DOI: 10.1016/S0960-894X(01)00129-9  0.479
2002 Kinghorn AD, Soejarto DD. Discovery of terpenoid and phenolic sweeteners from plants Pure and Applied Chemistry. 74: 1169-1179. DOI: 10.1351/Pac200274071169  0.445
2002 Kim NC, Kinghorn AD. Sweet-tasting and sweetness-modifying constituents of plants Studies in Natural Products Chemistry. 27: 3-57. DOI: 10.1016/S1572-5995(02)80033-3  0.454
2001 Waffo-Téguo P, Hawthorne ME, Cuendet M, Mérillon JM, Kinghorn AD, Pezzuto JM, Mehta RG. Potential cancer-chemopreventive activities of wine stilbenoids and flavans extracted from grape (Vitis vinifera) cell cultures. Nutrition and Cancer. 40: 173-9. PMID 11962253 DOI: 10.1207/S15327914Nc402_14  0.399
2001 Silva GL, Cui B, Chávez D, You M, Chai HB, Rasoanaivo P, Lynn SM, O'Neill MJ, Lewis JA, Besterman JM, Monks A, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Modulation of the multidrug-resistance phenotype by new tropane alkaloid aromatic esters from Erythroxylum pervillei Journal of Natural Products. 64: 1514-1520. PMID 11754602 DOI: 10.1021/Np010295+  0.593
2001 Lee D, Bhat KPL, Fong HHS, Farnsworth NR, Pezzuto JM, Kinghorn AD. Aromatase inhibitors from Broussonetia papyrifera Journal of Natural Products. 64: 1286-1293. PMID 11678652 DOI: 10.1021/np010288l  0.384
2001 Gu JQ, Park EJ, Luyengi L, Hawthorne ME, Mehta RG, Farnsworth NR, Pezzuto JM, Kinghorn AD. Constituents of Eugenia sandwicensis with potential cancer chemopreventive activity Phytochemistry. 58: 121-127. PMID 11524121 DOI: 10.1016/S0031-9422(01)00180-7  0.42
2001 Lee D, Cuendet M, Vigo JS, Graham JG, Cabieses F, Fong HH, Pezzuto JM, Kinghorn AD. A novel cyclooxygenase-inhibitory stilbenolignan from the seeds of Aiphanes aculeata. Organic Letters. 3: 2169-71. PMID 11440571 DOI: 10.1021/Ol015985J  0.479
2001 Ito A, Cui B, Chávez D, Chai HB, Shin YG, Kawanishi K, Kardono LBS, Riswan S, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Cytotoxic polyacetylenes from the twigs of Ochanostachys amentacea Journal of Natural Products. 64: 246-248. PMID 11430012 DOI: 10.1021/Np000484C  0.545
2001 Park EJ, Lee D, Shin YG, Lantvit DD, van Breemen RB, Kinghorn AD, Pezzuto JM. Analysis of 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors using liquid chromatography-electrospray mass spectrometry. Journal of Chromatography. B, Biomedical Sciences and Applications. 754: 327-32. PMID 11339276 DOI: 10.1016/S0378-4347(00)00620-4  0.332
2001 Oberlies NH, Burgess JP, Navarro HA, Pinos RE, Soejarto DD, Farnsworth NR, Kinghorn AD, Wani MC, Wall ME. Bioactive constituents of the roots of Licania intrapetiolaris. Journal of Natural Products. 64: 497-501. PMID 11325234 DOI: 10.1021/Np0005006  0.384
2001 Waffo-Teguo P, Lee D, Cuendet M, Mérillon J, Pezzuto JM, Kinghorn AD. Two new stilbene dimer glucosides from grape (Vitis vinifera) cell cultures. Journal of Natural Products. 64: 136-8. PMID 11170689 DOI: 10.1021/Np000426R  0.457
2001 Westenburg HE, Lee KJ, Lee SK, Fong HH, van Breemen RB, Pezzuto JM, Kinghorn AD. Activity-guided isolation of antioxidative constituents of Cotinus coggygria. Journal of Natural Products. 63: 1696-8. PMID 11141121 DOI: 10.1021/Np000292H  0.452
2001 Chadwick LR, Wu CD, Kinghorn AD. ISOLATION OF ALKALOIDS FROM GOLDENSEAL (HYDRASTIS CANADENSIS RHIZOMES) USING pH-ZONE REFINING COUNTERCURRENT CHROMATOGRAPHY Journal of Liquid Chromatography & Related Technologies. 24: 2445-2453. DOI: 10.1081/Jlc-100105950  0.355
2001 Chávez D, Chai HB, Chagwedera TE, Gao Q, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Novel stilbenes isolated from the root bark of Ekebergia benguelensis Tetrahedron Letters. 42: 3685-3688. DOI: 10.1016/S0040-4039(01)00560-3  0.604
2000 Chang LC, Gills JJ, Bhat KPL, Luyengi L, Farnsworth NR, Pezzuto JM, Kinghorn AD. Activity-guided isolation of constituents of Cerbera manghas with antiproliferative and antiestrogenic activities Bioorganic and Medicinal Chemistry Letters. 10: 2431-2434. PMID 11078194 DOI: 10.1016/S0960-894X(00)00477-7  0.301
2000 Seo EK, Wani MC, Wall ME, Navarro H, Mukherjee R, Farnsworth NR, Kinghorn AD. New bioactive aromatic compounds from Vismia guianensis Phytochemistry. 55: 35-42. PMID 11021642 DOI: 10.1016/S0031-9422(00)00208-9  0.404
2000 Chang LC, Song LL, Park EJ, Luyengi L, Lee KJ, Farnsworth NR, Pezzuto JM, Kinghorn AD. Bioactive constituents of Thuja occidentalis Journal of Natural Products. 63: 1235-1238. PMID 11000026 DOI: 10.1021/Np0001575  0.475
2000 Jeong HJ, Chang LC, Kim HK, Kim IH, Kinghorn AD, Pezzuto JM. Aromatase inhibitors from Isodon excisus var. coreanus. Archives of Pharmacal Research. 23: 243-5. PMID 10896056 DOI: 10.1007/Bf02976453  0.415
2000 Chang LC, Chávez D, Song LL, Farnsworth NR, Pezzuto JM, Kinghorn AD. Absolute configuration of novel bioactive flavonoids from Tephrosia purpurea Organic Letters. 2: 515-518. PMID 10814365 DOI: 10.1021/Ol990407C  0.494
2000 Peraza-Sánchez SR, Chávez D, Chai HB, Shin YG, García R, Mejía M, Fairchild CR, Lane KE, Menendez AT, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Cytotoxic constituents of the roots of Ekmanianthe longiflora. Journal of Natural Products. 63: 492-5. PMID 10785421 DOI: 10.1021/Np990528L  0.496
2000 Seo EK, Chai HB, Chagwedera TE, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. 5-(4-Hydroxyphenethenyl)-4,7-dimethoxycoumarin, a new constituent of Monotes engleri Planta Medica. 66: 182-184. PMID 10763599 DOI: 10.1055/S-0029-1243128  0.519
2000 Lee D, Kang SJ, Lee SH, Ro J, Lee K, Kinghorn AD. Phenolic compounds from the leaves of Cornus controversa. Phytochemistry. 53: 405-7. PMID 10703066 DOI: 10.1016/S0031-9422(99)00502-6  0.375
2000 Seo E, Kinghorn AD. Bioactive constituents of the family differocarpaceae Studies in Natural Products Chemistry. 23: 531-561. DOI: 10.1016/S1572-5995(00)80137-4  0.414
2000 Chang LC, Chávez D, Gills JJ, Fong HH, Pezzuto JM, Kinghorn A. Rubiasins A–C, new anthracene derivatives from the roots and stems of Rubia cordifolia Tetrahedron Letters. 41: 7157-7162. DOI: 10.1016/S0040-4039(00)01205-3  0.471
2000 Chang LC, Bhat KP, Fong HH, Pezzuto JM, Kinghorn A. Novel Bioactive Steroidal Alkaloids from Pachysandra procumbens Tetrahedron. 56: 3133-3138. DOI: 10.1016/S0040-4020(00)00232-5  0.339
1999 Cui B, Lee YH, Chai H, Tucker JC, Fairchild CR, Raventos-Suarez C, Long B, Lane KE, Menendez AT, Beecher CW, Cordell GA, Pezzuto JM, Kinghorn AD. Cytotoxic sesquiterpenoids from Ratibida columnifera. Journal of Natural Products. 62: 1545-50. PMID 10579870 DOI: 10.1021/Np990260Y  0.494
1999 Seo EK, Huang L, Wall ME, Wani MC, Navarro H, Mukherjee R, Farnsworth NR, Kinghorn AD. New biphenyl compounds with DNA strand-scission activity from Clusia paralicola Journal of Natural Products. 62: 1484-1487. PMID 10579857 DOI: 10.1021/np9900775  0.345
1999 Seo EK, Wall ME, Wani MC, Navarro H, Mukherjee R, Farnsworth NR, Kinghorn AD. Cytotoxic constituents from the roots of Tovomita brevistaminea Phytochemistry. 52: 669-674. PMID 10570828 DOI: 10.1016/S0031-9422(99)00274-5  0.498
1999 Chung HS, Chang LC, Lee SK, Shamon LA, Van Breemen RB, Mehta RG, Farnsworth NR, Pezzuto JM, Kinghorn AD. Flavonoid constituents of Chorizanthe diffusa with potential cancer chemopreventive activity Journal of Agricultural and Food Chemistry. 47: 36-41. PMID 10563845 DOI: 10.1021/Jf980784O  0.439
1999 Ito A, Lee YH, Chai HB, Gupta MP, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. 1',2',3',4'-Tetradehydrotubulosine, a cytotoxic alkaloid from Pogonopus speciosus Journal of Natural Products. 62: 1346-1348. PMID 10514334 DOI: 10.1021/np990255u  0.574
1999 Cui B, Chai H, Dong Y, Horgen FD, Hansen B, Madulid DA, Soejarto DD, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Quinoline alkaloids from Acronychia laurifolia Phytochemistry. 52: 95-98. PMID 10466225 DOI: 10.1016/S0031-9422(99)00039-4  0.626
1999 Lee SK, Luyengi L, Gerhäuser C, Mar W, Lee K, Mehta RG, Kinghorn AD, Pezzuto JM. Inhibitory effect of munetone, an isoflavonoid, on 12-O-tetradecanoylphorbol 13-acetate-induced ornithine decarboxylase activity. Cancer Letters. 136: 59-65. PMID 10211940 DOI: 10.1016/S0304-3835(98)00309-7  0.356
1999 Seo EK, Chai H, Constant HL, Santisuk T, Reutrakul V, Beecher CWW, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Resveratrol tetramers from Vatica diospyroides Journal of Organic Chemistry. 64: 6976-6983. DOI: 10.1021/Jo9902087  0.588
1998 Lee IS, Kaneda N, Suttisri R, El-Lakany AM, Sabri NN, Kinghorn AD. New orthoquinones from the roots of Salvia lanigera. Planta Medica. 64: 632-4. PMID 17253304 DOI: 10.1055/S-2006-957536  0.703
1998 Cui B, Chai H, Santisuk T, Reutrakul V, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Novel cytotoxic acylated oligorhamnosides from Mezzettia leptopoda Journal of Natural Products. 61: 1535-1538. PMID 9868159 DOI: 10.1021/Np980270J  0.445
1998 Lee SK, Cui B, Mehta RR, Kinghorn AD, Pezzuto JM. Cytostatic mechanism and antitumor potential of novel 1H-cyclopenta[b]benzofuran lignans isolated from Aglaia elliptica. Chemico-Biological Interactions. 115: 215-28. PMID 9851291 DOI: 10.1016/S0009-2797(98)00073-8  0.432
1998 Chang LC, Bhat KPL, Pisha E, Kennelly EJ, Fong HHS, Pezzuto JM, Kinghorn AD. Activity-guided isolation of steroidal alkaloid antiestrogen-binding site inhibitors from Pachysandra procumbens Journal of Natural Products. 61: 1257-1262. PMID 9784163 DOI: 10.1021/Np980162X  0.548
1998 Kinghorn AD, Kaneda N, Baek NI, Kennelly EJ, Soejarto DD. Noncariogenic intense natural sweeteners Medicinal Research Reviews. 18: 347-360. PMID 9735874 DOI: 10.1002/(Sici)1098-1128(199809)18:5<347::Aid-Med5>3.0.Co;2-T  0.619
1998 Lee SK, Qing WG, Mar W, Luyengi L, Mehta RG, Kawanishi K, Fong HH, Beecher CW, Kinghorn AD, Pezzuto JM. Angoline and chelerythrine, benzophenanthridine alkaloids that do not inhibit protein kinase C. The Journal of Biological Chemistry. 273: 19829-33. PMID 9677417 DOI: 10.1074/Jbc.273.31.19829  0.353
1998 Poobrasert O, Constant HL, Beecher CWW, Farnsworth NR, Kinghorn AD, Pezzuto JM, Cordell GA, Santisuk T, Reutrakul V. Xanthones from the twigs of Mammea siamensis Phytochemistry. 47: 1661-1663. PMID 9612959 DOI: 10.1016/S0031-9422(97)00820-0  0.616
1998 Cui B, Chai H, Constant HL, Santisuk T, Reutrakul V, Beecher CWW, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Limonoids from Azadirachta excelsa Phytochemistry. 47: 1283-1287. PMID 9611828 DOI: 10.1016/S0031-9422(97)00711-5  0.628
1998 Gamez EJ, Luyengi L, Lee SK, Zhu LF, Zhou BN, Fong HH, Pezzuto JM, Kinghorn AD. Antioxidant flavonoid glycosides from Daphniphyllum calycinum. Journal of Natural Products. 61: 706-8. PMID 9599286 DOI: 10.1021/Np9800203  0.332
1998 Huang L, Wall ME, Wani MC, Navarro H, Santisuk T, Reutrakul V, Seo EK, Farnsworth NR, Kinghorn AD. New compounds with DNA strand-scission activity from the combined leaf and stem of Uvaria hamiltonii Journal of Natural Products. 61: 446-450. PMID 9584399 DOI: 10.1021/np9703609  0.333
1998 Kinghorn AD, Yuny E. Chromatographic/Chromatographic Spectroscopic Combination Methods for the Analysis of Botanical Drugs Drug Information Journal. 32: 487-495. DOI: 10.1177/009286159803200221  0.351
1998 Kinghorn AD. Virtual Activity, Real Pharmacology. Different Approaches to the Search for Bioactive Natural Compounds Edited by Luisella Verotta (Università Degli Studi Di Milano). Research Signpost, Tivandrum, India. 1997. xi + 237 pp. 18 × 23.5 cm. $40.00. ISBN 81-86481-17-6. Journal of Natural Products. 61: 1575-1575. DOI: 10.1021/Np9802466  0.363
1997 Chang LC, Gerhäuser C, Song L, Farnsworth NR, Pezzuto JM, Kinghorn AD. Activity-guided isolation of constituents of Tephrosia purpurea with the potential to induce the phase II enzyme, quinone reductase. Journal of Natural Products. 60: 869-73. PMID 9322358 DOI: 10.1021/Np970236P  0.384
1997 Seo EK, Silva GL, Chai HB, Chagwedera TE, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Cytotoxic prenylated flavanones from Monotes engleri. Phytochemistry. 45: 509-15. PMID 9190085 DOI: 10.1016/S0031-9422(96)00871-0  0.542
1997 Fullas F, Wani MC, Wall ME, Tucker JC, Beecher CW, Kinghorn AD. Triterpenes from the combined leaf and stem of Lithospermum caroliniense. Phytochemistry. 43: 1303-5. PMID 8987910 DOI: 10.1016/S0031-9422(96)00422-0  0.318
1997 Jang M, Cai L, Udeani GO, Slowing KV, Thomas CF, Beecher CW, Fong HH, Farnsworth NR, Kinghorn AD, Mehta RG, Moon RC, Pezzuto JM. Cancer chemopreventive activity of resveratrol, a natural product derived from grapes. Science (New York, N.Y.). 275: 218-20. PMID 8985016 DOI: 10.1126/Science.275.5297.218  0.355
1997 Mbwambo ZH, Lee SK, Mshiu EN, Pezzuto JM, Kinghorn AD. Constituents from the stem wood of Euphorbia quinquecostata with phorbol dibutyrate receptor-binding inhibitory activity. Journal of Natural Products. 59: 1051-5. PMID 8946746 DOI: 10.1021/Np960412E  0.316
1997 Huang L, Fullas F, McGivney RJ, Brown DM, Wani MC, Wall ME, Tucker JC, Beecher CW, Pezzuto JM, Kinghorn AD. A new prenylated flavonol from the root of Petalostemon purpureus. Journal of Natural Products. 59: 290-2. PMID 8882432 DOI: 10.1021/np960068l  0.377
1997 Kuk Hyun Shin, Wen Sick Woo, Soon Sung Lim, Chang Sub Shim, Ha Sook Chung, Kennelly EJ, Kinghorn AD. Elgonica-dimers A and B, two potent alcohol metabolism inhibitory constituents of Aloe arborescens Journal of Natural Products. 60: 1180-1182. DOI: 10.1021/np9703104  0.541
1997 Kennelly EJ, Gerhäuser C, Song LL, Graham JG, Beecher CWW, Pezzuto JM, Kinghorn AD. Induction of Quinone Reductase by Withanolides Isolated from Physalis philadelphica (Tomatillos) Journal of Agricultural and Food Chemistry. 45: 3771-3777. DOI: 10.1021/Jf970246W  0.672
1997 Silva GL, Gil RR, Cui B, Chai H, Santisuk T, Srisook E, Reutrakul V, Tuchinda P, Sophasan S, Sujarit S, Upatham S, Lynn SM, Farthing JE, Yang S, Lewis JA, ... ... Kinghorn A, et al. Novel cytotoxic ring-a seco-cycloartane triterpenes from Gardenia coronaria and G. sootepensis Tetrahedron. 53: 529-538. DOI: 10.1016/S0040-4020(96)01003-4  0.719
1997 Chung MS, Kim NC, Long L, Shamon L, Ahmad WY, Sagrero-Nieves L, Kardono LBS, Kennelly EJ, Pezzuto JM, Soejarto DD, Kinghorn AD. Dereplication of saccharide and polyol constituents of candidate sweet-tasting plants: Isolation of the sesquiterpene glycoside mukurozioside IIb as a sweet principle of Sapindus rarak Phytochemical Analysis. 8: 49-54. DOI: 10.1002/(Sici)1099-1565(199703)8:2<49::Aid-Pca339>3.0.Co;2-C  0.634
1996 Wall ME, Wani MC, Brown DM, Fullas F, Olwald JB, Josephson FF, Thornton NM, Pezzuto JM, Beecher CW, Farnsworth NR, Cordell GA, Kinghorn AD. Effect of tannins on screening of plant extracts for enzyme inhibitory activity and techniques for their removal. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 3: 281-5. PMID 23195084 DOI: 10.1016/S0944-7113(96)80067-5  0.455
1996 Fullas F, Kornberg LJ, Wani MC, Wall ME, Farnsworth NR, Chagwedera TE, Kinghorn AD. Two new aromatic constitutents from the rootwood of Aeschynomene mimosifolia. Journal of Natural Products. 59: 190-2. PMID 8991952 DOI: 10.1021/Np960052V  0.368
1996 Kennelly EJ, Suttisri R, Kinghorn AD. Novel sweet-tasting saponins of the cycloartane, oleanane, secodammarane, and steroidal types Advances in Experimental Medicine and Biology. 405: 13-24. PMID 8910692 DOI: 10.1007/978-1-4613-0413-5_2  0.776
1996 Luyengi L, Suh N, Fong HH, Pezzuto JM, Kinghorn AD. A lignan and four terpenoids from Brucea javanica that induce differentiation with cultured HL-60 promyelocytic leukemia cells. Phytochemistry. 43: 409-12. PMID 8862033 DOI: 10.1016/0031-9422(96)00258-0  0.427
1996 Chaudhuri SK, Fullas F, Wani MC, Wall ME, Tucker JC, Beecher CW, Kinghorn AD. Two isoflavones from the bark of Petalostemon purpureus. Phytochemistry. 41: 945-6. PMID 8835466 DOI: 10.1016/0031-9422(95)00636-2  0.353
1996 Sturm S, Gil RR, Chai HB, Ngassapa OD, Santisuk T, Reutrakul V, Howe A, Moss M, Besterman JM, Yang SL, Farthing JE, Tait RM, Lewis JA, O'Neill MJ, Farnsworth NR, ... ... Kinghorn AD, et al. Lupane derivatives from Lophopetalum wallichii with farnesyl protein transferase inhibitory activity. Journal of Natural Products. 59: 658-63. PMID 8759161 DOI: 10.1021/Np960370U  0.729
1996 Lee IS, Shamon LA, Chai HB, Chagwedera TE, Besterman JM, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Cell-cycle specific cytotoxicity mediated by rearranged ent-kaurene diterpenoids isolated from Parinari curatellifolia. Chemico-Biological Interactions. 99: 193-204. PMID 8620568 DOI: 10.1016/0009-2797(95)03669-5  0.608
1996 Cordell GA, Beecher CWW, Kinghorn AD, Pezzuto JM, Constant HL, Chai H, Fang L, Seo E, Long L, Cui B, Slowing-Barillas K. The dereplication of plant-derived natural products Studies in Natural Products Chemistry. 19: 749-791. DOI: 10.1016/S1572-5995(96)80018-4  0.56
1996 Kennelly EJ, Cai L, Kim NC, Kinghorn AD. Abrusoside E, a further sweet-tasting cycloartane glycoside from the leaves of Abrus precatorius Phytochemistry. 41: 1381-1383. DOI: 10.1016/0031-9422(95)00792-X  0.565
1995 Chaudhuri SK, Huang L, Fullas F, Brown DM, Wani MC, Wall ME, Tucker JC, Beecher CWW, Kinghorn AD. Isolation and structure identification of an active DNA strand-scission agent, (+)-3,4-di-hydroxy-8,9-methylenedioxypterocarpan. Journal of Natural Products. 58: 1966-1969. PMID 8691215 DOI: 10.1021/Np50126A030  0.389
1995 Fullas F, Brown DM, Wani MC, Wall ME, Chagwedera TE, Farnsworth NR, Pezzuto JM, Kinghorn AD. Gummiferol, a cytotoxic polyacetylene from the leaves of Adenia gummifera. Journal of Natural Products. 58: 1625-8. PMID 8676132 DOI: 10.1021/Np50124A027  0.385
1995 Kinghorn AD. The discovery of drugs from higher plants. Biotechnology (Reading, Mass.). 26: 81-108. PMID 7749315 DOI: 10.1016/B978-0-7506-9003-4.50010-1  0.36
1995 Wickramaratne DBM, Mar W, Chai H, Castillo JJ, Farnsworth NR, Soejarto DD, Cordell GA, Pezzuto JM, Kinghorn AD. Cytotoxic constituents of Bursera permollis Planta Medica. 61: 80-81. PMID 7701001 DOI: 10.1055/S-2006-958008  0.478
1995 You M, Wickramaratne DB, Silva GL, Chai H, Chagwedera TE, Farnsworth NR, Cordell GA, Kinghorn AD, Pezzuto JM. (-)-Roemerine, an aporphine alkaloid from Annona senegalensis that reverses the multidrug-resistance phenotype with cultured cells. Journal of Natural Products. 58: 598-604. PMID 7623038 DOI: 10.1021/Np50118A021  0.493
1995 Suttisri R, Lee IS, Kinghorn AD. Plant-derived triterpenoid sweetness inhibitors. Journal of Ethnopharmacology. 47: 9-26. PMID 7564423 DOI: 10.1016/0378-8741(95)01248-C  0.722
1995 Pengsuparp T, Cai L, Constant H, Fong HH, Lin LZ, Kinghorn AD, Pezzuto JM, Cordell GA, Ingolfsdóttir K, Wagner H. Mechanistic evaluation of new plant-derived compounds that inhibit HIV-1 reverse transcriptase. Journal of Natural Products. 58: 1024-31. PMID 7561895 DOI: 10.1021/Np50121A006  0.466
1995 Silva GL, Chai H, Gupta MP, Farnsworth NR, Cordell GA, Pezzuto JM, Beecher CW, Kinghorn AD. Cytotoxic biflavonoids from Selaginella willdenowii. Phytochemistry. 40: 129-34. PMID 7546547 DOI: 10.1016/0031-9422(95)00212-P  0.559
1995 Pisha E, Chai H, Lee IS, Chagwedera TE, Farnsworth NR, Cordell GA, Beecher CW, Fong HH, Kinghorn AD, Brown DM. Discovery of betulinic acid as a selective inhibitor of human melanoma that functions by induction of apoptosis. Nature Medicine. 1: 1046-51. PMID 7489361 DOI: 10.1038/Nm1095-1046  0.533
1995 Kinghorn AD, Fullas F, Hussain RA. Structure-activity relationship of highly sweet natural products Studies in Natural Products Chemistry. 15: 3-41. DOI: 10.1016/S1572-5995(06)80129-8  0.383
1995 Lee I, Ma X, Chai H, Madulid DA, Lamont RB, O'Neill MJ, Besterman JM, Farnsworth NR, Soejarto DD, Cordell GA, Pezzuto JM, Kinghorn AD. Novel cytotoxic labdane diterpenoids from Neouvaria acuminatissima Tetrahedron. 51: 21-28. DOI: 10.1016/0040-4020(94)00945-Q  0.553
1994 You M, Ma X, Mukherjee R, Farnsworth NR, Cordell GA, Kinghorn AD, Pezzuto JM. Indole alkaloids from Peschiera laeta that enhance vinblastine-mediated cytotoxicity with multidrug-resistant cells. Journal of Natural Products. 57: 1517-22. PMID 7853002 DOI: 10.1021/Np50113A007  0.497
1994 Meurer-Grimes B, Kinghorn AD, Balandrin MF. Human Medicinal Agents from Plants. Brittonia. 46: 153. DOI: 10.2307/2807160  0.308
1994 Suttisri R, Kinghorn AD, Wright AD, Stichert O. Neo-clerodane diterpenoids and other constituents from Baccharis genistelloides Phytochemistry. 35: 443-446. DOI: 10.1016/S0031-9422(00)94778-2  0.674
1994 Luyengi L, Lee I, Mar W, Fong HH, Pezzuto JM, Kinghorn A. Rotenoids and chalcones from Mundulea sericea that inhibit phorbol ester-induced ornithine decarboxylase activity Phytochemistry. 36: 1523-1526. DOI: 10.1016/S0031-9422(00)89755-1  0.371
1993 Pereda-Miranda R, Mata R, Anaya AL, Wickramaratne DB, Pezzuto JM, Kinghorn AD. Tricolorin A, major phytogrowth inhibitor from Ipomoea tricolor. Journal of Natural Products. 56: 571-82. PMID 8496705 DOI: 10.1021/Np50094A018  0.413
1993 Baek NI, Chung MS, Shamon L, Kardono LBS, Tsauri S, Padmawinata K, Pezzuto JM, Soejarto DD, Kinghorn AD. Selligueain A, a novel highly sweet proanthocyanidin from the rhizomes of Selliguea feei Journal of Natural Products. 56: 1532-1538. PMID 8254348 DOI: 10.1021/Np50099A011  0.35
1993 Wickramaratne DB, Pengsuparp T, Mar W, Chai HB, Chagwedera TE, Beecher CW, Farnsworth NR, Kinghorn AD, Pezzuto JM, Cordell GA. Novel antimitotic dibenzocyclo-octadiene lignan constituents of the stem bark of Steganotaenia araliacea. Journal of Natural Products. 56: 2083-90. PMID 8133298 DOI: 10.1021/Np50102A009  0.566
1993 Suttisri R, Chung MS, Kinghorn AD, Sticher O, Hashimoto Y. Periandrin V, a further sweet triterpene glycoside from Periandra dulcis. Phytochemistry. 34: 405-8. PMID 7764140 DOI: 10.1016/0031-9422(93)80018-N  0.693
1993 Dai J, Suttisri R, Bordas E, Soejarto DD, Kinghorn AD. Clerodane diterpenoids from Baccharis articulata Phytochemistry. 34: 1087-1090. DOI: 10.1016/S0031-9422(00)90720-9  0.721
1993 Nasution MP, Kinghorn A. (+)-13α-(4′-Hydroxytigloyloxy) lupanine from Ormosia krugii Phytochemistry. 32: 1603-1605. DOI: 10.1016/0031-9422(93)85188-W  0.304
1993 Dai J, Chai H, Pezzuto JM, Kinghorn AD, Tsauri S, Padmawinata K. Cytotoxic constituents of the roots of the indonesian medicinal plantFibraurea chloroleuca Phytotherapy Research. 7: 290-294. DOI: 10.1002/Ptr.2650070406  0.463
1993 Kinghorn AD. Chi-Tang Ho. Chang Y. Lee and Mou-Tuan Huang (Eds). Phenolic compounds in food and their effects on health. I. Analysis, occurrence & Chemistry. II. Antioxidants & Cancer chemopreventionacs. ACS Symposium Series Nos. 506 and 507, American Chemical Society, Washington, DC, 1992; I, xiv + 338 pp., $74.95, ISBN 0–8412-2475–7; II, xi + 402 pp., $84.95, ISBN 0–8412-2476–5. Two-volume set, $149.95 Phytochemical Analysis. 4: 89-89. DOI: 10.1002/Pca.2800040208  0.304
1992 Kardono LB, Angerhofer CK, Tsauri S, Padmawinata K, Pezzuto JM, Kinghorn AD. Cytotoxic and antimalarial constituents of the roots of Eurycoma longifolia. Journal of Natural Products. 54: 1360-7. PMID 1800638 DOI: 10.1021/np50077a020  0.326
1992 Kaneda N, Pezzuto JM, Kinghorn AD, Farnsworth NR, Santisuk T, Tuchinda P, Udchachon J, Reutrakul V. Plant anticancer agents, L. cytotoxic triterpenes from Sandoricum koetjape stems Journal of Natural Products. 55: 654-659. PMID 1517737 DOI: 10.1021/Np50083A016  0.39
1992 Fullas F, Soejarto DD, Kinghorn AD. A bitter-tasting trihomolabdane arabinoside from Baccharis gaudichaudiana Phytochemistry. 31: 2543-2545. DOI: 10.1016/0031-9422(92)83323-Q  0.374
1991 Kaneda N, Pezzuto JM, Soejarto DD, Kinghorn AD, Farnsworth NR, Santisuk T, Tuchinda P, Udchachon J, Reutrakul V. Plant anticancer agents, XLVIII. New cytotoxic flavonoids from Muntingia calabura roots Journal of Natural Products. 54: 196-206. PMID 2045815 DOI: 10.1021/Np50073A019  0.481
1991 Kardono LB, Tsauri S, Padmawinata K, Pezzuto JM, Kinghorn AD. Cytotoxic constituents of the bark of Plumeria rubra collected in Indonesia. Journal of Natural Products. 53: 1447-55. PMID 1965200 DOI: 10.1021/Np50072A008  0.398
1991 Duh CY, Kinghorn AD, Pezzuto JM. Cell-cycle specific cytotoxicity mediated by stizophyllin (2 alpha,3 beta,12 beta-trihydroxypregna-4,7,16-trien-20-one), a novel electrophilic pregnane isolated from Stizophyllum riparium. Chemico-Biological Interactions. 80: 43-56. PMID 1913978 DOI: 10.1016/0009-2797(91)90030-B  0.338
1991 Tan GT, Pezzuto JM, Kinghorn AD, Hughes SH. Evaluation of natural products as inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase. Journal of Natural Products. 54: 143-54. PMID 1710653  0.32
1991 Rasoanaivo P, Kaneda N, Kinghorn AD, Farnsworth NR. Folotsoside A, a New Pregnane Glycoside from Folotsia sarcostemmoides Journal of Natural Products. 54: 1672-1676. DOI: 10.1021/Np50078A031  0.312
1991 Fullas F, Hussain RA, Bordas E, Pezzuto JM, Soejarto DD, Kinghorn AD. Gaudichaudiosides A-E, five novel diterpene glycoside constituents from the sweet-tasting plant, Baccharis gaudichaudiana Tetrahedron. 47: 8515-8522. DOI: 10.1016/S0040-4020(01)82394-2  0.386
1991 Tuchinda P, Udchachon J, Reutrakul V, Santisuk T, Taylor WC, Farnsworth NR, Pezzuto JM, Kinghorn AD. Bioactive butenolides from Melodorum fruticosum Phytochemistry. 30: 2685-2689. DOI: 10.1016/0031-9422(91)85123-H  0.451
1990 Hussain RA, Lin YM, Poveda LJ, Bordas E, Chung BS, Pezzuto JM, Soejarto DD, Kinghorn AD. Plant-derived sweetening agents: saccharide and polyol constituents of some sweet-tasting plants. Journal of Ethnopharmacology. 28: 103-15. PMID 2314108 DOI: 10.1016/0378-8741(90)90067-4  0.322
1990 Gao F, Wang H, Mabry TJ, Kinghorn AD. Dihydroflavonol sweeteners and other constituents from Hymenoxys turneri Phytochemistry. 29: 2865-2869. DOI: 10.1016/0031-9422(90)87092-9  0.301
1989 Kinghorn AD, Soejarto DD. Intensely sweet compounds of natural origin Medicinal Research Reviews. 9: 91-115. PMID 2644498 DOI: 10.1002/Med.2610090105  0.407
1989 Choi Y, Kinghorn AD, Shi X, Zhang H, Teo BK. Abrusoside A: a new type of highly sweet triterpene glycoside Journal of the Chemical Society, Chemical Communications. 887-888. DOI: 10.1039/C39890000887  0.31
1989 Kim J, Kinghorn AD. Further steroidal and flavonoid constituents of the sweet plant, Polypodium glycyrrhiza Phytochemistry. 28: 1225-1228. DOI: 10.1016/0031-9422(89)80214-6  0.335
1988 Nanayakkara NP, Hussain RA, Pezzuto JM, Soejarto DD, Kinghorn AD. An intensely sweet dihydroflavonol derivative based on a natural product lead compound. Journal of Medicinal Chemistry. 31: 1250-3. PMID 3373494 DOI: 10.1021/Jm00401A030  0.437
1988 Choi YH, Pezzuto JM, Kinghorn AD, Farnsworth NR. Plant anticancer agents, XLVI. Cytotoxic casbane-type constituents of Agrostistachys hookeri. Journal of Natural Products. 51: 110-6. PMID 3373221 DOI: 10.1021/Np50055A016  0.433
1988 Kim J, Pezzuto JM, Soejarto DD, Lang FA, Kinghorn AD. Polypodoside A, an intensely sweet constituent of the rhizomes of Polypodium glycyrrhiza Journal of Natural Products. 51: 1166-1172. PMID 3236009 DOI: 10.1021/Np50060A019  0.327
1988 Kinghorn AD, Hussain RA, Robbins EF, Balandrin MF, Stirton CH, Evans SV. Alkaloid distribution in seeds of Ormosia, Pericopsis and Haplormosia Phytochemistry. 27: 439-444. DOI: 10.1016/0031-9422(88)83116-9  0.342
1987 Nanayakkara NPD, Klocke JA, Compadre CM, Hussain RA, Pezzuto JM, Kinghorn AD. Characterization and feeding deterrent effects on the aphid, Schizaphis graminum, of some derivatives of the sweet compounds, stevioside and rebaudioside A Journal of Natural Products. 50: 434-441. PMID 3668559 DOI: 10.1021/Np50051A015  0.307
1987 Hamburger M, Handa SS, Cordell GA, Kinghorn AD, Farnsworth NR. Plant anticancer agents, XLIII. (E,E)-7, 12-dioxo-octadeca-8, 10-dien-1-oic acid (ostopanic acid), a cytotoxic fatty acid from Ostodes Paniculata. Journal of Natural Products. 50: 281-3. PMID 3655798  0.398
1986 Pezzuto JM, Dhammika Nanayakkara NP, Compadre CM, Swanson SM, Kinghorn AD, Guenthner TM, Sparnins VL, Lam LKT. Characterization of bacterial mutagenicity mediated by 13-hydroxy-ent-kaurenoic acid (steviol) and several structurally-related derivatives and evaluation of potential to induce glutathione S-transferase in mice Mutation Research/Genetic Toxicology. 169: 93-103. PMID 3512998 DOI: 10.1016/0165-1218(86)90088-1  0.362
1985 Marshall GT, Klocke JA, Lin LJ, Kinghorn AD. Effects of diterpene esters of tigliane, daphnane, ingenane, and lathyrane types on pink bollworm,Pectinophora gossypiella saunders (Lepidoptera: Gelechiidae). Journal of Chemical Ecology. 11: 191-206. PMID 24309846 DOI: 10.1007/Bf00988202  0.374
1985 Arisawa M, Kinghorn AD, Cordell GA, Phoebe CH, Farnsworth NR. Plant Anticancer Agents XXXVI. Schottenol Glucoside from Baccharis coridifolia and Ipomopsis aggregata1. Planta Medica. 51: 544-5. PMID 17345296 DOI: 10.1055/S-2007-969601  0.421
1985 Arisawa M, Fujita A, Morita N, Kinghorn AD, Cordell GA, Farnsworth NR. Plant Anticancer Agents XXXV. Further Constituents of Simaba multiflora1,2. Planta Medica. 51: 348-9. PMID 17340534 DOI: 10.1055/S-2007-969512  0.547
1985 Fang X, Nanayakkara NP, Phoebe CH, Pezzuto JM, Kinghorn AD, Farnsworth NR. Plant Anticancer Agents XXXVII. Constituents of Amanoa oblongifolia1. Planta Medica. 51: 346-7. PMID 17340533 DOI: 10.1055/S-2007-969511  0.39
1985 Klocke JA, Arisawa M, Handa SS, Kinghorn AD, Cordell GA, Farnsworth NR. Growth inhibitory, insecticidal and antifeedant effects of some antileukemic and cytotoxic quassinoids on two species of agricultural pests. Experientia. 41: 379-82. PMID 3972085 DOI: 10.1007/Bf02004516  0.451
1985 Che CT, Fang XD, Phoebe CH, Kinghorn AD, Farnsworth NR, Yellin B, Hecht SM. High-field 1H-NMR spectral analysis of some cucurbitacins. Journal of Natural Products. 48: 429-34. PMID 3839841 DOI: 10.1021/Np50039A010  0.355
1985 Fiebig M, Pezzuto JM, Soejarto DD, Kinghorn AD. Koenoline, a further cytotoxic carbazole alkaloid from Murraya koenigii Phytochemistry. 24: 3041-3043. DOI: 10.1016/0031-9422(85)80052-2  0.421
1984 Ji-Xian G, Handa SS, Pezzuto JM, Kinghorn AD, Farnsworth NR. Plant Anticancer Agents XXXIII. Constituents of Passerina vulgaris1. Planta Medica. 50: 264-5. PMID 17340308 DOI: 10.1055/S-2007-969695  0.354
1984 Arisawa M, Funayama S, Pezzuto JM, Kinghorn AD, Cordell GA, Farnsworth NR. Potential anticancer agents XXXII. Hydroquinone from Ipomopsis aggregata. Journal of Natural Products. 47: 393-4. PMID 6736973 DOI: 10.1021/np50032a037  0.384
1984 Badawi MM, Handa SS, Kinghorn AD, Cordell GA, Farnsworth NR. Plant anticancer agents XXVII: Antileukemic and cytotoxic constituents of Dirca occidentalis (Thymelaeaceae). Journal of Pharmaceutical Sciences. 72: 1285-7. PMID 6644588 DOI: 10.1002/Jps.2600721112  0.581
1984 Arisawa M, Pezzuto JM, Kinghorn AD, Cordell GA, Farnsworth NR. Plant anticancer agents. XXX: Cucurbitacins from Ipomopsis aggregata (Polemoniaceae). Journal of Pharmaceutical Sciences. 73: 411-3. PMID 6546946 DOI: 10.1002/Jps.2600730335  0.526
1983 Handa SS, Kinghorn AD, Cordell GA, Farnsworth NR. Plant anticancer agents. XXVI. Constituents of Peddiea fischeri. Journal of Natural Products. 46: 248-50. PMID 6875580 DOI: 10.1021/np50026a020  0.446
1983 Arisawa M, Kinghorn AD, Cordell GA, Farnsworth NR. Plant anticancer agents. XXIV. Alkaloid constituents of Simaba multiflora. Journal of Natural Products. 46: 222-5. PMID 6875577 DOI: 10.1021/np50026a016  0.528
1983 Arisawa M, Kinghorn AD, Cordell GA, Farnsworth NR. Plant anticancer agents. XXIII. 6 alpha-senecioyloxychaparrin, a new antileukemic quassinoid from Simaba multiflora. Journal of Natural Products. 46: 218-21. PMID 6875576 DOI: 10.1021/np50026a015  0.428
1983 Handa SS, Kinghorn AD, Cordell GA, Farnsworth NR. Plant anticancer agents. XXII. Isolation of a phorbol diester and its delta 5,6-7 beta-hydroperoxide derivative from Ostodes paniculata. Journal of Natural Products. 46: 123-6. PMID 6854337 DOI: 10.1021/np50025a013  0.45
1983 Handa SS, Kinghorn AD, Cordell GA, Farnsworth NR. Plant anticancer agents XXV. Constituents of Soulamea soulameoides. Journal of Natural Products. 46: 359-64. PMID 6619884 DOI: 10.1021/np50027a011  0.5
1983 Lin LJ, Kinghorn AD. 8-methoxyingol esters from the latex of Euphorbia hermentiana Phytochemistry. 22: 2795-2799. DOI: 10.1016/S0031-9422(00)97699-4  0.322
1982 Balandrin MF, Robbins EF, Kinghorn AD. Alkaloid distribution in some species of the Papilionaceous tribes Thermopsideae and Genisteae Biochemical Systematics and Ecology. 10: 307-311. DOI: 10.1016/0305-1978(82)90004-7  0.309
1981 Seida AA, Kinghorn AD, Cordell GA, Farnsworth NR. Isolation of bergapten and marmesin from Balanites aegyptiaca. Planta Medica. 43: 92-3. PMID 17402017 DOI: 10.1055/S-2007-971481  0.445
1981 Kinghorn AD. Major skin-irritant principle from Synadenium grantii. Journal of Pharmaceutical Sciences. 69: 1446-7. PMID 7463336 DOI: 10.1002/Jps.2600691228  0.305
1981 Gunasekera SP, Kinghorn AD, Cordell GA, Farnsworth NR. Plant anticancer agents. XIX Constituents of Aquilaria malaccensis. Journal of Natural Products. 44: 569-72. PMID 7320738 DOI: 10.1021/Np50017A010  0.566
1981 Badawi MM, Seida AA, Kinghorn AD, Cordell GA, Farnsworth NR. Potential Anticancer Agents. XVIII. Constituents of Amyris pinnata Journal of Natural Products. 44: 331-334. DOI: 10.1021/Np50015A016  0.469
1981 Smolenski SJ, Kinghorn AD, Balandrin MF. Toxic constituents of legume forage plants Economic Botany. 35: 321-355. DOI: 10.1007/Bf02859125  0.432
1980 Mahmoud II, Kinghorn AD, Cordell GA, Farnsworth NR. Potential anticancer agents. XVI. Isolation of bicyclofarnesane sesquiterpenoids from Capsicodendron dinisii. Journal of Natural Products. 43: 365-71. PMID 7400822 DOI: 10.1021/np50009a008  0.543
1979 Seida AA, Kinghorn AD, Cordell GA, Farnsworth NR. Potential anticancer agents IX. Isolation of a new simaroubolide, 6alpha-tigloyloxychaparrinone, from Ailanthus integrifolia ssp. calycina (Simaroubaceae). Lloydia. 41: 584-7. PMID 732541  0.346
1979 Svoboda KS, Smolenski SJ, Kinghorn AD. Indole alkylamines from Tachigalia paniculata Journal of Natural Products. 42: 307-308. DOI: 10.1021/Np50003A014  0.33
1978 Ogura M, Cordell GA, Kinghorn AD, Farnsworth NR. Potential anticancer agents vi. Constituents of Ailanthus excelsa (Simaroubaceae). Lloydia. 40: 579-84. PMID 600027  0.373
1978 Jawad FH, Kinghorn AD, Doorenbos NJ, Billets S. Characterization and mass spectral analysis of some grayanotoxin derivatives. Biomedical Mass Spectrometry. 4: 331-6. PMID 597581 DOI: 10.1002/Bms.1200040603  0.37
1977 EVANS FJ, KINGHORN AD. A comparative phytochemical study of the diterpenes of some species of the genera Euphorbia and Elaeophorbia (Euphorbiaceae) Botanical Journal of the Linnean Society. 74: 23-35. DOI: 10.1111/J.1095-8339.1977.Tb01163.X  0.513
1975 Evans FJ, Kinghorn AD, Schmidt RJ. Some naturally occurring skin irritants. Acta Pharmacologica Et Toxicologica. 37: 250-6. PMID 1242607 DOI: 10.1111/J.1600-0773.1975.Tb00842.X  0.566
1975 Kinghorn AD, Evans FJ. A biological screen of selected species of the genus Euphorbia for skin irritant effects. Planta Medica. 28: 326-35. PMID 1208681  0.47
1975 Evans FJ, Kinghorn AD. The succulent euphorbias of Nigeria. Part I. Lloydia. 38: 363-5. PMID 1186440  0.49
1975 Kinghorn AD, Evans FJ. Skin irritants of Euphorbia fortissima. The Journal of Pharmacy and Pharmacology. 27: 329-33. PMID 239133 DOI: 10.1111/J.2042-7158.1975.Tb09450.X  0.593
1975 Soper CJ, Kinghorn AD, Evans FJ. Proceedings: Preliminary investigations on the mode of action of the cocarcinogen A1 using bacteria. The Journal of Pharmacy and Pharmacology. 27: 51P. PMID 2726  0.45
1975 Evans FJ, Schmidt RJ, Kinghorn AD. A microtechnique for the identification of diterpene ester inflammatory toxins Biological Mass Spectrometry. 2: 126-130. DOI: 10.1002/Bms.1200020304  0.488
1974 Kinghorn AD, Evans FJ. Occurrence of ingenol in Elaeophorbia species. Planta Medica. 26: 150-4. PMID 4414881 DOI: 10.1055/s-0028-1097982  0.446
1974 Kinghorn AD, Evans FJ. A quantitative gas-liquid chromatographic method for phorbol and related diterpenes as their acetates. The Journal of Pharmacy and Pharmacology. 26: 408-12. PMID 4154984 DOI: 10.1111/J.2042-7158.1974.Tb09305.X  0.485
1974 Evans F, Kinghorn A. A new ingenol type diterpene from the irritant fractions of Euphorbia myrsinites and Euphorbia biglandulosa Phytochemistry. 13: 2324-2325. DOI: 10.1016/0031-9422(74)85053-3  0.51
1973 Evans FJ, Kinghorn AD. Thin-layer chromatographic behaviour of the acetates of some polyfunctional diterpene alcohols of toxicological interest. Journal of Chromatography. 87: 443-8. PMID 4358219  0.447
1973 Evans FJ, Kinghorn AD. Proceedings: A screening procedure for Euphorbia co-carcinogenic irritants. The Journal of Pharmacy and Pharmacology. 25: Suppl:145P-146. PMID 4150549  0.453
Show low-probability matches.