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Nadezhda A. German, Ph.D. - Publications

Affiliations: 
2007 University of Iowa, Iowa City, IA 
 2014- Pharmaceutical Sciences Texas Tech University Health Sciences Center 
Area:
Pharmaceutical Chemistry
Website:
https://www.ttuhsc.edu/pharmacy/directory/details.aspx?eRaiderUserName=ngerman
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24 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Bandy R, Shahi S, Quagraine N, Shahbazi Nia S, Howlader MSI, Srivenugopal K, Stephan C, Das H, Mikelis CM, German NA. Mechanistic Aspects of Biphenyl Urea-Based Analogues in Triple-Negative Breast Cancer Cell Lines. Acs Pharmacology & Translational Science. 7: 120-136. PMID 38230276 DOI: 10.1021/acsptsci.3c00193  0.624
2023 Shahbazi Nia S, Hossain MA, Ji G, Jonnalagadda SK, Obeng S, Rahman MA, Sifat AE, Nozohouri S, Blackwell C, Patel D, Thompson J, Runyon S, Hiranita T, McCurdy CR, McMahon L, ... ... German NA, et al. Studies on diketopiperazine and dipeptide analogs as opioid receptor ligands. European Journal of Medicinal Chemistry. 254: 115309. PMID 37054561 DOI: 10.1016/j.ejmech.2023.115309  0.614
2022 Ashraf-Uz-Zaman M, Ji G, Tidwell D, Yin L, Thakolwiboon S, Pan J, Junell R, Griffin Z, Shahi S, Barthels D, Sajib MS, Trippier PC, Mikelis CM, Das H, Avila M, ... ... German NA, et al. Evaluation of Urea-Based Inhibitors of the Dopamine Transporter Using the Experimental Autoimmune Encephalomyelitis Model of Multiple Sclerosis. Acs Chemical Neuroscience. PMID 34978174 DOI: 10.1021/acschemneuro.1c00647  0.699
2021 Hossain MA, German NA. Update on modulators of quorum sensing pathways in Pseudomonas Aeruginosa. Current Topics in Medicinal Chemistry. PMID 34561982 DOI: 10.2174/1568026621666210924160004  0.614
2021 Al-Hilal TA, Hossain MA, Alobaida A, Alam F, Keshavarz A, Nozik-Grayck E, Stenmark KR, German NA, Ahsan F. Design, synthesis and biological evaluations of a long-acting, hypoxia-activated prodrug of fasudil, a ROCK inhibitor, to reduce its systemic side-effects. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 33915222 DOI: 10.1016/j.jconrel.2021.04.030  0.613
2020 Ashraf-Uz-Zaman M, Shahi S, Akwii R, Sajib MS, Farshbaf MJ, Kallem RR, Putnam W, Wang W, Zhang R, Alvina K, Trippier PC, Mikelis CM, German NA. Design, synthesis and structure-activity relationship study of novel urea compounds as FGFR1 inhibitors to treat metastatic triple-negative breast cancer. European Journal of Medicinal Chemistry. 209: 112866. PMID 33039722 DOI: 10.1016/j.ejmech.2020.112866  0.714
2020 Ashraf-Uz-Zaman M, Bhalerao A, Mikelis CM, Cucullo L, German NA. Assessing the Current State of Lung Cancer Chemoprevention: A Comprehensive Overview. Cancers. 12. PMID 32429547 DOI: 10.3390/cancers12051265  0.707
2019 Hossain MA, Sattenapally N, Parikh HI, Li W, Rumbaugh KP, German NA. Design, synthesis, and evaluation of compounds capable of reducing Pseudomonas aeruginosa virulence. European Journal of Medicinal Chemistry. 111800. PMID 31706639 DOI: 10.1016/J.Ejmech.2019.111800  0.642
2018 Ashraf-Uz-Zaman M, Sajib MS, Cucullo L, Mikelis CM, German NA. Analogs of penfluridol as chemotherapeutic agents with reduced central nervous system activity. Bioorganic & Medicinal Chemistry Letters. PMID 30389290 DOI: 10.1016/j.bmcl.2018.10.036  0.737
2018 Nguyen T, Gamage TF, Decker AM, German N, Langston TL, Farquhar CE, Kenakin TP, Wiley JL, Thomas BF, Zhang Y. Diarylureas Containing 5-Membered Heterocycles as CB1 Receptor Allosteric Modulators: Design, Synthesis, and Pharmacological Evaluation. Acs Chemical Neuroscience. PMID 30188693 DOI: 10.1021/Acschemneuro.8B00396  0.339
2018 Dukat M, Jain AD, German N, Ferrara-Pontoriero R, Huang Y, Ma Y, Schulte MK, Glennon RA. des-Formylflustrabromine (dFBr): A Structure-Activity Study on its Ability to Potentiate the Action of Acetylcholine at α4β2 Nicotinic Acetylcholine Receptors. Acs Chemical Neuroscience. PMID 30028943 DOI: 10.1021/Acschemneuro.8B00156  0.617
2018 Patel R, Hossain MA, German N, Al-Ahmad AJ. Gliotoxin penetrates and impairs the integrity of the human blood-brain barrier in vitro. Mycotoxin Research. PMID 30006720 DOI: 10.1007/S12550-018-0320-7  0.57
2017 Nguyen T, German N, Decker AM, Langston TL, Gamage TF, Farquhar CE, Li JX, Wiley JL, Thomas BF, Zhang Y. Novel Diarylurea Based Allosteric Modulators of the Cannabinoid CB1 Receptor: Evaluation of Importance of 6-Pyrrolidinylpyridinyl Substitution. Journal of Medicinal Chemistry. PMID 28792219 DOI: 10.1021/Acs.Jmedchem.7B00707  0.366
2015 Nguyen T, German N, Decker AM, Li JX, Wiley JL, Thomas BF, Kenakin TP, Zhang Y. Structure-activity relationships of substituted 1H-indole-2-carboxamides as CB1 receptor allosteric modulators. Bioorganic & Medicinal Chemistry. 23: 2195-203. PMID 25797163 DOI: 10.1016/J.Bmc.2015.02.058  0.408
2015 Perrey DA, German NA, Decker AM, Thorn D, Li JX, Gilmour BP, Thomas BF, Harris DL, Runyon SP, Zhang Y. Effect of 1-substitution on tetrahydroisoquinolines as selective antagonists for the orexin-1 receptor. Acs Chemical Neuroscience. 6: 599-614. PMID 25643283 DOI: 10.1016/J.Drugalcdep.2015.07.659  0.401
2015 Zhang Y, Perrey DA, Harris DL, German NA, Decker AM, Gilmour BP, Thomas BF. Structure-activity relationship studies on the tetrahydroisoquinoline-based orexin 1 receptor antagonists: The 1-benzyl position Drug and Alcohol Dependence. 146. DOI: 10.1016/J.Drugalcdep.2014.09.765  0.319
2014 German N, Decker AM, Gilmour BP, Gay EA, Wiley JL, Thomas BF, Zhang Y. Diarylureas as allosteric modulators of the cannabinoid CB1 receptor: structure-activity relationship studies on 1-(4-chlorophenyl)-3-{3-[6-(pyrrolidin-1-yl)pyridin-2-yl]phenyl}urea (PSNCBAM-1). Journal of Medicinal Chemistry. 57: 7758-69. PMID 25162172 DOI: 10.1021/Jm501042U  0.354
2013 Perrey DA, German NA, Gilmour BP, Li JX, Harris DL, Thomas BF, Zhang Y. Substituted tetrahydroisoquinolines as selective antagonists for the orexin 1 receptor. Journal of Medicinal Chemistry. 56: 6901-16. PMID 23941044 DOI: 10.1021/Jm400720H  0.366
2011 German N, Kim JS, Jain A, Dukat M, Pandya A, Ma Y, Weltzin M, Schulte MK, Glennon RA. Deconstruction of the α4β2 nicotinic acetylcholine receptor positive allosteric modulator desformylflustrabromine Journal of Medicinal Chemistry. 54: 7259-7267. PMID 21905680 DOI: 10.1021/Jm200834X  0.587
2010 Malik M, Marks KR, Schwanz HA, German N, Drlica K, Kerns RJ. Effect of N-1/c-8 ring fusion and C-7 ring structure on fluoroquinolone lethality. Antimicrobial Agents and Chemotherapy. 54: 5214-21. PMID 20855738 DOI: 10.1128/Aac.01054-10  0.708
2009 Rosen JD, German N, Kerns RJ. Efficient Synthesis of the 2-amino-6-chloro-4-cyclopropyl-7-fluoro-5-methoxy-pyrido[1,2-c]pyrimidine-1,3-dione core ring system. Tetrahedron Letters. 50: 785-789. PMID 20160840 DOI: 10.1016/J.Tetlet.2008.11.121  0.624
2008 German N, Malik M, Rosen JD, Drlica K, Kerns RJ. Use of gyrase resistance mutants to guide selection of 8-methoxy-quinazoline-2,4-diones. Antimicrobial Agents and Chemotherapy. 52: 3915-21. PMID 18765690 DOI: 10.1128/Aac.00330-08  0.594
2008 German N, Wei P, Kaatz GW, Kerns RJ. Synthesis and evaluation of fluoroquinolone derivatives as substrate-based inhibitors of bacterial efflux pumps. European Journal of Medicinal Chemistry. 43: 2453-63. PMID 18358571 DOI: 10.1016/J.Ejmech.2008.01.042  0.609
2008 German N, Kaatz GW, Kerns RJ. Synthesis and evaluation of PSSRI-based inhibitors of Staphylococcus aureus multidrug efflux pumps. Bioorganic & Medicinal Chemistry Letters. 18: 1368-73. PMID 18242086 DOI: 10.1016/J.Bmcl.2008.01.014  0.635
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