| Year |
Citation |
Score |
| 2021 |
Verma DK, Seo BA, Ghosh A, Ma SX, Hernandez-Quijada K, Andersen JK, Ko HS, Kim YH. Alpha-Synuclein Preformed Fibrils Induce Cellular Senescence in Parkinson's Disease Models. Cells. 10. PMID 34359864 DOI: 10.3390/cells10071694 |
0.344 |
|
| 2020 |
Walton CC, Begelman D, Nguyen W, Andersen JK. Senescence as an Amyloid Cascade: The Amyloid Senescence Hypothesis. Frontiers in Cellular Neuroscience. 14: 129. PMID 32508595 DOI: 10.3389/Fncel.2020.00129 |
0.371 |
|
| 2020 |
Anand N, Holcom A, Broussalian M, Schmidt M, Chinta SJ, Lithgow GJ, Andersen JK, Chamoli M. Dysregulated iron metabolism in C. elegans catp-6/ATP13A2 mutant impairs mitochondrial function. Neurobiology of Disease. 104786. PMID 32032734 DOI: 10.1016/J.Nbd.2020.104786 |
0.4 |
|
| 2019 |
Guttuso T, Andrzejewski KL, Lichter DG, Andersen JK. Targeting kinases in Parkinson's disease: A mechanism shared by LRRK2, neurotrophins, exenatide, urate, nilotinib and lithium. Journal of the Neurological Sciences. 402: 121-130. PMID 31129265 DOI: 10.1016/J.Jns.2019.05.016 |
0.324 |
|
| 2019 |
Tom S, Rane A, Katewa AS, Chamoli M, Matsumoto RR, Andersen JK, Chinta SJ. Gedunin Inhibits Oligomeric Aβ-Induced Microglia Activation Via Modulation of Nrf2-NF-κB Signaling. Molecular Neurobiology. PMID 31127528 DOI: 10.1007/S12035-019-1636-9 |
0.336 |
|
| 2019 |
Walton CC, Andersen JK. Unknown fates of (brain) oxidation or UFO: close encounters with neuronal senescence. Free Radical Biology & Medicine. PMID 30639615 DOI: 10.1016/J.Freeradbiomed.2019.01.012 |
0.476 |
|
| 2018 |
Woods G, Andersen JK. Screening method for identifying toxicants capable of inducing astrocyte senescence. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 30010981 DOI: 10.1093/Toxsci/Kfy181 |
0.321 |
|
| 2018 |
Chamoli M, Chinta SJ, Andersen JK. An inducible MAO-B mouse model of Parkinson's disease: a tool towards better understanding basic disease mechanisms and developing novel therapeutics. Journal of Neural Transmission (Vienna, Austria : 1996). PMID 29713806 DOI: 10.1007/S00702-018-1887-Z |
0.399 |
|
| 2018 |
Rane A, Rajagopalan S, Ahuja M, Thomas B, Chinta SJ, Andersen JK. Hsp90 Co-chaperone p23 Contributes to Dopaminergic Mitochondrial Stress via Stabilization of PHD2: Implications for Parkinson's disease. Neurotoxicology. PMID 29471019 DOI: 10.1016/J.Neuro.2018.02.012 |
0.441 |
|
| 2018 |
Chinta SJ, Woods G, Demaria M, Rane A, Zou Y, McQuade A, Rajagopalan S, Limbad C, Madden DT, Campisi J, Andersen JK. Cellular Senescence Is Induced by the Environmental Neurotoxin Paraquat and Contributes to Neuropathology Linked to Parkinson's Disease. Cell Reports. 22: 930-940. PMID 29386135 DOI: 10.1016/J.Celrep.2017.12.092 |
0.444 |
|
| 2018 |
Andersen JK. CELLULAR SENESCENCE: A NOVEL CONTRIBUTOR TO BRAIN AGING AND NEURODEGENERATIVE DISEASE Innovation in Aging. 2: 220-220. DOI: 10.1093/Geroni/Igy023.810 |
0.357 |
|
| 2018 |
Andersen JK. UNCOVERING A NOVEL PATHWAY FOR NEURONAL AUTOPHAGY: A NEW THERAPEUTIC TARGET FOR ALZHEIMER’S AND PARKINSON’S DISEASE? Innovation in Aging. 2: 745-745. DOI: 10.1093/Geroni/Igy023.2747 |
0.341 |
|
| 2017 |
Das B, Rajagopalan S, Joshi GS, Xu L, Luo D, Andersen JK, Todi SV, Dutta AK. A novel iron (II) preferring dopamine agonist chelator D-607 significantly suppresses α-syn- and MPTP-induced toxicities in vivo. Neuropharmacology. PMID 28533164 DOI: 10.1016/J.Neuropharm.2017.05.019 |
0.406 |
|
| 2017 |
Leonoudakis D, Rane A, Angeli S, Lithgow GJ, Andersen JK, Chinta SJ. Anti-Inflammatory and Neuroprotective Role of Natural Product Securinine in Activated Glial Cells: Implications for Parkinson's Disease. Mediators of Inflammation. 2017: 8302636. PMID 28473732 DOI: 10.1155/2017/8302636 |
0.394 |
|
| 2016 |
Siddiqui A, Rane A, Rajagopalan S, Chinta SJ, Andersen JK. Detrimental effects of oxidative losses in parkin activity in a model of sporadic Parkinson's disease are attenuated by restoration of PGC1alpha. Neurobiology of Disease. PMID 27185595 DOI: 10.1016/J.Nbd.2016.05.009 |
0.455 |
|
| 2016 |
Rajagopalan S, Rane A, Chinta SJ, Andersen JK. Regulation of ATP13A2 via PHD2-HIF1α Signaling Is Critical for Cellular Iron Homeostasis: Implications for Parkinson's Disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 1086-95. PMID 26818499 DOI: 10.1523/Jneurosci.3117-15.2016 |
0.492 |
|
| 2015 |
Siddiqui A, Bhaumik D, Chinta SJ, Rane A, Rajagopalan S, Lieu CA, Lithgow GJ, Andersen JK. Mitochondrial Quality Control via the PGC1α-TFEB Signaling Pathway Is Compromised by Parkin Q311X Mutation But Independently Restored by Rapamycin. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 12833-44. PMID 26377470 DOI: 10.1523/Jneurosci.0109-15.2015 |
0.372 |
|
| 2015 |
Lazzara CA, Riley RR, Rane A, Andersen JK, Kim YH. The combination of lithium and L-dopa/Carbidopa reduces MPTP-induced abnormal involuntary movements (AIMs) via calpain-1 inhibition in a mouse model: Relevance for Parkinson's disease therapy. Brain Research. PMID 26119916 DOI: 10.1016/J.Brainres.2015.06.018 |
0.405 |
|
| 2015 |
Chinta SJ, Woods G, Rane A, Demaria M, Campisi J, Andersen JK. Cellular senescence and the aging brain. Experimental Gerontology. 68: 3-7. PMID 25281806 DOI: 10.1016/J.Exger.2014.09.018 |
0.367 |
|
| 2015 |
Aleyasin H, Karuppagounder SS, Kumar A, Sleiman S, Basso M, Ma T, Siddiq A, Chinta SJ, Brochier C, Langley B, Haskew-Layton R, Bane SL, Riggins GJ, Gazaryan I, Starkov AA, ... Andersen JK, et al. Antihelminthic benzimidazoles are novel HIF activators that prevent oxidative neuronal death via binding to tubulin. Antioxidants & Redox Signaling. 22: 121-34. PMID 24766300 DOI: 10.1089/Ars.2013.5595 |
0.38 |
|
| 2015 |
Andersen JK, Chinta S. Parkinson’s Disease and Aging Advances in Geroscience. 229-255. DOI: 10.1007/978-3-319-23246-1_8 |
0.329 |
|
| 2014 |
Lieu CA, Dewey CM, Chinta SJ, Rane A, Rajagopalan S, Batir S, Kim YH, Andersen JK. Lithium prevents parkinsonian behavioral and striatal phenotypes in an aged parkin mutant transgenic mouse model. Brain Research. 1591: 111-7. PMID 25452026 DOI: 10.1016/J.Brainres.2014.10.032 |
0.422 |
|
| 2014 |
Angeli S, Barhydt T, Jacobs R, Killilea DW, Lithgow GJ, Andersen JK. Manganese disturbs metal and protein homeostasis in Caenorhabditis elegans. Metallomics : Integrated Biometal Science. 6: 1816-23. PMID 25057947 DOI: 10.1039/C4Mt00168K |
0.423 |
|
| 2014 |
Shah M, Rajagopalan S, Xu L, Voshavar C, Shurubor Y, Beal F, Andersen JK, Dutta AK. The high-affinity D2/D3 agonist D512 protects PC12 cells from 6-OHDA-induced apoptotic cell death and rescues dopaminergic neurons in the MPTP mouse model of Parkinson's disease. Journal of Neurochemistry. 131: 74-85. PMID 24848702 DOI: 10.1111/Jnc.12767 |
0.371 |
|
| 2014 |
Neuhaus JF, Baris OR, Hess S, Moser N, Schröder H, Chinta SJ, Andersen JK, Kloppenburg P, Wiesner RJ. Catecholamine metabolism drives generation of mitochondrial DNA deletions in dopaminergic neurons. Brain : a Journal of Neurology. 137: 354-65. PMID 24163249 DOI: 10.1093/Brain/Awt291 |
0.379 |
|
| 2014 |
Rajagopalan S, Chinta SJ, Andersen JK. Pharmacological prolyl hydroxylase domain inhibition as a therapeutic target for Parkinson's disease. Cns & Neurological Disorders Drug Targets. 13: 120-5. PMID 24040809 DOI: 10.2174/18715273113126660131 |
0.412 |
|
| 2013 |
Chinta SJ, Lieu CA, Demaria M, Laberge RM, Campisi J, Andersen JK. Environmental stress, ageing and glial cell senescence: a novel mechanistic link to Parkinson's disease? Journal of Internal Medicine. 273: 429-36. PMID 23600398 DOI: 10.1111/Joim.12029 |
0.449 |
|
| 2013 |
Lieu CA, Chinta SJ, Rane A, Andersen JK. Age-related behavioral phenotype of an astrocytic monoamine oxidase-B transgenic mouse model of Parkinson's disease. Plos One. 8: e54200. PMID 23326597 DOI: 10.1371/Journal.Pone.0054200 |
0.4 |
|
| 2013 |
Chinta SJ, Ganesan A, Reis-Rodrigues P, Lithgow GJ, Andersen JK. Anti-inflammatory role of the isoflavone diadzein in lipopolysaccharide-stimulated microglia: implications for Parkinson's disease. Neurotoxicity Research. 23: 145-53. PMID 22573480 DOI: 10.1007/S12640-012-9328-5 |
0.359 |
|
| 2012 |
Siddiqui A, Rivera-Sánchez S, Castro Mdel R, Acevedo-Torres K, Rane A, Torres-Ramos CA, Nicholls DG, Andersen JK, Ayala-Torres S. Mitochondrial DNA damage is associated with reduced mitochondrial bioenergetics in Huntington's disease. Free Radical Biology & Medicine. 53: 1478-88. PMID 22709585 DOI: 10.1016/J.Freeradbiomed.2012.06.008 |
0.362 |
|
| 2012 |
Siddiqui A, Chinta SJ, Mallajosyula JK, Rajagopolan S, Hanson I, Rane A, Melov S, Andersen JK. Selective binding of nuclear alpha-synuclein to the PGC1alpha promoter under conditions of oxidative stress may contribute to losses in mitochondrial function: implications for Parkinson's disease. Free Radical Biology & Medicine. 53: 993-1003. PMID 22705949 DOI: 10.1016/J.Freeradbiomed.2012.05.024 |
0.406 |
|
| 2012 |
Chinta SJ, Rajagopalan S, Ganesan A, Andersen JK. A possible novel anti-inflammatory mechanism for the pharmacological prolyl hydroxylase inhibitor 3,4-dihydroxybenzoate: implications for use as a therapeutic for Parkinson's disease. Parkinson's Disease. 2012: 364684. PMID 22666629 DOI: 10.1155/2012/364684 |
0.457 |
|
| 2012 |
Siddiqui A, Hanson I, Andersen JK. Mao-B elevation decreases parkin's ability to efficiently clear damaged mitochondria: protective effects of rapamycin. Free Radical Research. 46: 1011-8. PMID 22329629 DOI: 10.3109/10715762.2012.662277 |
0.406 |
|
| 2012 |
Abbott RD, Ross GW, Tanner CM, Andersen JK, Masaki KH, Rodriguez BL, White LR, Petrovitch H. Late-life hemoglobin and the incidence of Parkinson's disease. Neurobiology of Aging. 33: 914-20. PMID 20709430 DOI: 10.1016/J.Neurobiolaging.2010.06.023 |
0.372 |
|
| 2012 |
Siddiqui A, Chinta S, Hansen I, Rane A, Andersen J. 3.137 OXIDATIVE STRESS, ALPHA-SYNUCLEIN, AND EPIGENETIC AFFECTS IN THE PARKINSONIAN BRAIN Parkinsonism & Related Disorders. 18: S198. DOI: 10.1016/S1353-8020(11)70853-7 |
0.319 |
|
| 2011 |
Campisi J, Andersen JK, Kapahi P, Melov S. Cellular senescence: a link between cancer and age-related degenerative disease? Seminars in Cancer Biology. 21: 354-9. PMID 21925603 DOI: 10.1016/J.Semcancer.2011.09.001 |
0.357 |
|
| 2011 |
Kim YH, Rane A, Lussier S, Andersen JK. Lithium protects against oxidative stress-mediated cell death in α-synuclein-overexpressing in vitro and in vivo models of Parkinson's disease. Journal of Neuroscience Research. 89: 1666-75. PMID 21710541 DOI: 10.1002/Jnr.22700 |
0.447 |
|
| 2011 |
Gogoi S, Antonio T, Rajagopalan S, Reith M, Andersen J, Dutta AK. Dopamine D₂/D₃ agonists with potent iron chelation, antioxidant and neuroprotective properties: potential implication in symptomatic and neuroprotective treatment of Parkinson's disease. Chemmedchem. 6: 991-5. PMID 21567969 DOI: 10.1002/Cmdc.201100140 |
0.398 |
|
| 2011 |
Choi SW, Gerencser AA, Lee DW, Rajagopalan S, Nicholls DG, Andersen JK, Brand MD. Intrinsic bioenergetic properties and stress sensitivity of dopaminergic synaptosomes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 4524-34. PMID 21430153 DOI: 10.1523/Jneurosci.5817-10.2011 |
0.39 |
|
| 2011 |
Danielson SR, Held JM, Oo M, Riley R, Gibson BW, Andersen JK. Quantitative mapping of reversible mitochondrial Complex I cysteine oxidation in a Parkinson disease mouse model. The Journal of Biological Chemistry. 286: 7601-8. PMID 21196577 DOI: 10.1074/Jbc.M110.190108 |
0.382 |
|
| 2011 |
Peng J, Andersen JK. Mutant α-synuclein and aging reduce neurogenesis in the acute 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease. Aging Cell. 10: 255-62. PMID 21108729 DOI: 10.1111/J.1474-9726.2010.00656.X |
0.401 |
|
| 2011 |
Kim YH, Lussier S, Rane A, Choi SW, Andersen JK. Inducible dopaminergic glutathione depletion in an alpha-synuclein transgenic mouse model results in age-related olfactory dysfunction Neuroscience. 172: 379-386. PMID 21055449 DOI: 10.1016/J.Neuroscience.2010.10.072 |
0.388 |
|
| 2011 |
Chinta SJ, Andersen JK. Nitrosylation and nitration of mitochondrial complex I in Parkinson's disease. Free Radical Research. 45: 53-8. PMID 20815786 DOI: 10.3109/10715762.2010.509398 |
0.43 |
|
| 2011 |
Siddiqui A, Mallajosyula JK, Rane A, Andersen JK. Corrigendum to "Ability to delay neuropathological events associated with astrocytic MAO-B increase in a Parkinsonian mouse model: Implications for early intervention on disease progression" [Neurobiol Dis. 40/2 (2010) 444-448] Neurobiology of Disease. 43: 526. DOI: 10.1016/J.Nbd.2010.12.013 |
0.305 |
|
| 2011 |
Siddiqui A, Chinta S, Andersen J, Hanson I, Rane A. Oxidative stress and Parkinson's: Linking alpha-synuclein to epigenetics Free Radical Biology and Medicine. 51: S4. DOI: 10.1016/J.Freeradbiomed.2011.10.009 |
0.339 |
|
| 2010 |
Peng J, Oo ML, Andersen JK. Synergistic effects of environmental risk factors and gene mutations in Parkinson's disease accelerate age-related neurodegeneration. Journal of Neurochemistry. 115: 1363-73. PMID 21039522 DOI: 10.1111/J.1471-4159.2010.07036.X |
0.417 |
|
| 2010 |
Chinta SJ, Mallajosyula JK, Rane A, Andersen JK. Mitochondrial α-synuclein accumulation impairs complex I function in dopaminergic neurons and results in increased mitophagy in vivo. Neuroscience Letters. 486: 235-9. PMID 20887775 DOI: 10.1016/J.Neulet.2010.09.061 |
0.386 |
|
| 2010 |
Siddiqui A, Mallajosyula JK, Rane A, Andersen JK. Ability to delay neuropathological events associated with astrocytic MAO-B increase in a Parkinsonian mouse model: implications for early intervention on disease progression. Neurobiology of Disease. 40: 444-8. PMID 20655384 DOI: 10.1016/J.Nbd.2010.07.004 |
0.388 |
|
| 2010 |
Lee DW, Andersen JK. Iron elevations in the aging Parkinsonian brain: a consequence of impaired iron homeostasis? Journal of Neurochemistry. 112: 332-9. PMID 20085612 DOI: 10.1111/J.1471-4159.2009.06470.X |
0.385 |
|
| 2010 |
Zhu W, Li X, Xie W, Luo F, Kaur D, Andersen JK, Jankovic J, Le W. Genetic iron chelation protects against proteasome inhibition-induced dopamine neuron degeneration. Neurobiology of Disease. 37: 307-13. PMID 19818853 DOI: 10.1016/J.Nbd.2009.09.024 |
0.403 |
|
| 2009 |
Andersen JK. Arvid Carlsson: an early pioneer in translational medicine. Science Translational Medicine. 1: 2ps3. PMID 20368162 DOI: 10.1126/Scitranslmed.3000149 |
0.311 |
|
| 2009 |
Kaur D, Rajagopalan S, Andersen JK. Chronic expression of H-ferritin in dopaminergic midbrain neurons results in an age-related expansion of the labile iron pool and subsequent neurodegeneration: implications for Parkinson's disease. Brain Research. 1297: 17-22. PMID 19699718 DOI: 10.1016/J.Brainres.2009.08.043 |
0.432 |
|
| 2009 |
Danielson SR, Held JM, Schilling B, Oo M, Gibson BW, Andersen JK. Preferentially increased nitration of alpha-synuclein at tyrosine-39 in a cellular oxidative model of Parkinson's disease. Analytical Chemistry. 81: 7823-8. PMID 19697948 DOI: 10.1021/Ac901176T |
0.382 |
|
| 2009 |
Lee DW, Rajagopalan S, Siddiq A, Gwiazda R, Yang L, Beal MF, Ratan RR, Andersen JK. Inhibition of prolyl hydroxylase protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity: model for the potential involvement of the hypoxia-inducible factor pathway in Parkinson disease. The Journal of Biological Chemistry. 284: 29065-76. PMID 19679656 DOI: 10.1074/Jbc.M109.000638 |
0.457 |
|
| 2009 |
Mallajosyula JK, Chinta SJ, Rajagopalan S, Nicholls DG, Andersen JK. Metabolic control analysis in a cellular model of elevated MAO-B: relevance to Parkinson's disease. Neurotoxicity Research. 16: 186-93. PMID 19526285 DOI: 10.1007/S12640-009-9032-2 |
0.366 |
|
| 2009 |
Lee DW, Kaur D, Chinta SJ, Rajagopalan S, Andersen JK. A disruption in iron-sulfur center biogenesis via inhibition of mitochondrial dithiol glutaredoxin 2 may contribute to mitochondrial and cellular iron dysregulation in mammalian glutathione-depleted dopaminergic cells: implications for Parkinson's disease. Antioxidants & Redox Signaling. 11: 2083-94. PMID 19290777 DOI: 10.1089/Ars.2009.2489 |
0.435 |
|
| 2009 |
Chinta SJ, Rane A, Yadava N, Andersen JK, Nicholls DG, Polster BM. Reactive oxygen species regulation by AIF- and complex I-depleted brain mitochondria. Free Radical Biology & Medicine. 46: 939-47. PMID 19280713 DOI: 10.1016/J.Freeradbiomed.2009.01.010 |
0.361 |
|
| 2009 |
Chinta SJ, Poksay KS, Kaundinya G, Hart M, Bredesen DE, Andersen JK, Rao RV. Endoplasmic reticulum stress-induced cell death in dopaminergic cells: effect of resveratrol. Journal of Molecular Neuroscience : Mn. 39: 157-68. PMID 19145491 DOI: 10.1007/S12031-008-9170-7 |
0.358 |
|
| 2009 |
Kaur D, Lee D, Ragapolan S, Andersen JK. Glutathione depletion in immortalized midbrain-derived dopaminergic neurons results in increases in the labile iron pool: implications for Parkinson's disease. Free Radical Biology & Medicine. 46: 593-8. PMID 19118623 DOI: 10.1016/J.Freeradbiomed.2008.11.012 |
0.427 |
|
| 2009 |
Peng J, Stevenson FF, Oo ML, Andersen JK. Iron-enhanced paraquat-mediated dopaminergic cell death due to increased oxidative stress as a consequence of microglial activation. Free Radical Biology & Medicine. 46: 312-20. PMID 19027846 DOI: 10.1016/J.Freeradbiomed.2008.10.045 |
0.448 |
|
| 2008 |
Chinta SJ, Rane A, Poksay KS, Bredesen DE, Andersen JK, Rao RV. Coupling endoplasmic reticulum stress to the cell death program in dopaminergic cells: effect of paraquat. Neuromolecular Medicine. 10: 333-42. PMID 18773310 DOI: 10.1007/S12017-008-8047-9 |
0.397 |
|
| 2008 |
Vali S, Chinta SJ, Peng J, Sultana Z, Singh N, Sharma P, Sharada S, Andersen JK, Bharath MM. Insights into the effects of alpha-synuclein expression and proteasome inhibition on glutathione metabolism through a dynamic in silico model of Parkinson's disease: validation by cell culture data. Free Radical Biology & Medicine. 45: 1290-301. PMID 18761401 DOI: 10.1016/J.Freeradbiomed.2008.08.002 |
0.404 |
|
| 2008 |
Peng J, Xie L, Jin K, Greenberg DA, Andersen JK. Fibroblast growth factor 2 enhances striatal and nigral neurogenesis in the acute 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease Neuroscience. 153: 664-670. PMID 18407421 DOI: 10.1016/J.Neuroscience.2008.02.063 |
0.436 |
|
| 2008 |
Danielson SR, Andersen JK. Oxidative and nitrative protein modifications in Parkinson's disease. Free Radical Biology & Medicine. 44: 1787-94. PMID 18395015 DOI: 10.1016/J.Freeradbiomed.2008.03.005 |
0.461 |
|
| 2008 |
Chinta SJ, Andersen JK. Redox imbalance in Parkinson's disease. Biochimica Et Biophysica Acta. 1780: 1362-7. PMID 18358848 DOI: 10.1016/J.Bbagen.2008.02.005 |
0.484 |
|
| 2008 |
Mallajosyula JK, Kaur D, Chinta SJ, Rajagopalan S, Rane A, Nicholls DG, Di Monte DA, Macarthur H, Andersen JK. MAO-B elevation in mouse brain astrocytes results in Parkinson's pathology. Plos One. 3: e1616. PMID 18286173 DOI: 10.1371/Journal.Pone.0001616 |
0.462 |
|
| 2007 |
Chinta SJ, Kumar MJ, Hsu M, Rajagopalan S, Kaur D, Rane A, Nicholls DG, Choi J, Andersen JK. Inducible alterations of glutathione levels in adult dopaminergic midbrain neurons result in nigrostriatal degeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 13997-4006. PMID 18094238 DOI: 10.1523/Jneurosci.3885-07.2007 |
0.479 |
|
| 2007 |
Vali S, Mythri RB, Jagatha B, Padiadpu J, Ramanujan KS, Andersen JK, Gorin F, Bharath MMS. Integrating glutathione metabolism and mitochondrial dysfunction with implications for Parkinson's disease: A dynamic model Neuroscience. 149: 917-930. PMID 17936517 DOI: 10.1016/J.Neuroscience.2007.08.028 |
0.449 |
|
| 2007 |
Peng J, Peng L, Stevenson FF, Doctrow SR, Andersen JK. Iron and paraquat as synergistic environmental risk factors in sporadic Parkinson's disease accelerate age-related neurodegeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 6914-22. PMID 17596439 DOI: 10.1523/Jneurosci.1569-07.2007 |
0.444 |
|
| 2007 |
Kaur D, Peng J, Chinta SJ, Rajagopalan S, Di Monte DA, Cherny RA, Andersen JK. Increased murine neonatal iron intake results in Parkinson-like neurodegeneration with age. Neurobiology of Aging. 28: 907-13. PMID 16765489 DOI: 10.1016/J.Neurobiolaging.2006.04.003 |
0.37 |
|
| 2007 |
Kaur D, Rajagopalan S, Chinta S, Kumar J, Di Monte D, Cherny RA, Andersen JK. Chronic ferritin expression within murine dopaminergic midbrain neurons results in a progressive age-related neurodegeneration. Brain Research. 1140: 188-94. PMID 16631136 DOI: 10.1016/J.Brainres.2006.03.006 |
0.458 |
|
| 2006 |
Mythri RB, Jagatha B, Pradhan N, Andersen J, Bharath MMS. Mitochondrial Complex I Inhibition in Parkinson's Disease: How Can Curcumin Protect Mitochondria? Antioxidants & Redox Signaling. 9: 399-408. PMID 17184173 DOI: 10.1089/Ars.2006.1479 |
0.437 |
|
| 2006 |
Lee DW, Andersen JK. Role of HIF-1 in iron regulation: potential therapeutic strategy for neurodegenerative disorders. Current Molecular Medicine. 6: 883-93. PMID 17168739 DOI: 10.2174/156652406779010849 |
0.35 |
|
| 2006 |
Peng J, Xie L, Stevenson FF, Melov S, Di Monte DA, Andersen JK. Nigrostriatal dopaminergic neurodegeneration in the weaver mouse is mediated via neuroinflammation and alleviated by minocycline administration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 11644-51. PMID 17093086 DOI: 10.1523/Jneurosci.3447-06.2006 |
0.417 |
|
| 2006 |
Chinta SJ, Andersen JK. Reversible inhibition of mitochondrial complex I activity following chronic dopaminergic glutathione depletion in vitro: implications for Parkinson's disease. Free Radical Biology & Medicine. 41: 1442-8. PMID 17023271 DOI: 10.1016/J.Freeradbiomed.2006.08.002 |
0.462 |
|
| 2006 |
Chinta SJ, Rajagopalan S, Butterfield DA, Andersen JK. In vitro and in vivo neuroprotection by gamma-glutamylcysteine ethyl ester against MPTP: relevance to the role of glutathione in Parkinson's disease. Neuroscience Letters. 402: 137-41. PMID 16644116 DOI: 10.1016/J.Neulet.2006.03.056 |
0.45 |
|
| 2006 |
Chinta SJ, Kumar JM, Zhang H, Forman HJ, Andersen JK. Up-regulation of gamma-glutamyl transpeptidase activity following glutathione depletion has a compensatory rather than an inhibitory effect on mitochondrial complex I activity: implications for Parkinson's disease. Free Radical Biology & Medicine. 40: 1557-63. PMID 16632116 DOI: 10.1016/J.Freeradbiomed.2005.12.023 |
0.375 |
|
| 2006 |
Lee DW, Andersen JK, Kaur D. Iron dysregulation and neurodegeneration: the molecular connection. Molecular Interventions. 6: 89-97. PMID 16565471 DOI: 10.1124/Mi.6.2.6 |
0.313 |
|
| 2005 |
Bharath S, Andersen JK. Glutathione depletion in a midbrain-derived immortalized dopaminergic cell line results in limited tyrosine nitration of mitochondrial complex I subunits: Implications for Parkinson's disease Antioxidants and Redox Signaling. 7: 900-910. PMID 15998245 DOI: 10.1089/Ars.2005.7.900 |
0.471 |
|
| 2005 |
Peng J, Stevenson FF, Doctrow SR, Andersen JK. Superoxide dismutase/catalase mimetics are neuroprotective against selective paraquat-mediated dopaminergic neuron death in the substantial nigra: implications for Parkinson disease. The Journal of Biological Chemistry. 280: 29194-8. PMID 15946937 DOI: 10.1074/Jbc.M500984200 |
0.487 |
|
| 2005 |
McCormack AL, Atienza JG, Johnston LC, Andersen JK, Vu S, Di Monte DA. Role of oxidative stress in paraquat-induced dopaminergic cell degeneration. Journal of Neurochemistry. 93: 1030-7. PMID 15857406 DOI: 10.1111/J.1471-4159.2005.03088.X |
0.433 |
|
| 2005 |
Chinta SJ, Andersen JK. Dopaminergic neurons. The International Journal of Biochemistry & Cell Biology. 37: 942-6. PMID 15743669 DOI: 10.1016/J.Biocel.2004.09.009 |
0.44 |
|
| 2005 |
Hsu M, Srinivas B, Kumar J, Subramanian R, Andersen J. Glutathione depletion resulting in selective mitochondrial complex I inhibition in dopaminergic cells is via an NO-mediated pathway not involving peroxynitrite: implications for Parkinson's disease. Journal of Neurochemistry. 92: 1091-103. PMID 15715660 DOI: 10.1111/J.1471-4159.2004.02929.X |
0.449 |
|
| 2005 |
Boonplueang R, Akopian G, Stevenson FF, Kuhlenkamp JF, Lu SC, Walsh JP, Andersen JK. Increased susceptibility of glutathione peroxidase-1 transgenic mice to kainic acid-related seizure activity and hippocampal neuronal cell death. Experimental Neurology. 192: 203-14. PMID 15698635 DOI: 10.1016/J.Expneurol.2004.12.017 |
0.365 |
|
| 2005 |
Schilling B, Bharath M M S, Row RH, Murray J, Cusack MP, Capaldi RA, Freed CR, Prasad KN, Andersen JK, Gibson BW. Rapid purification and mass spectrometric characterization of mitochondrial NADH dehydrogenase (Complex I) from rodent brain and a dopaminergic neuronal cell line. Molecular & Cellular Proteomics : McP. 4: 84-96. PMID 15591592 DOI: 10.1074/Mcp.M400143-Mcp200 |
0.452 |
|
| 2005 |
Lithgow GJ, Andersen JK. Models of oxidative stress in the biology of aging Drug Discovery Today: Disease Models. 2: 273-277. DOI: 10.1016/J.Ddmod.2005.11.009 |
0.327 |
|
| 2004 |
Andersen JK. Iron dysregulation and Parkinson's disease. Journal of Alzheimer's Disease : Jad. 6: S47-52. PMID 15665414 DOI: 10.3233/Jad-2004-6S602 |
0.423 |
|
| 2004 |
Bharath S, Andersen JK. Catecholamines and protein deposition in Parkinson's and Alzheimer's disease: Old medicine, new targets Rejuvenation Research. 7: 92-94. PMID 15312295 DOI: 10.1089/1549168041553071 |
0.327 |
|
| 2004 |
Andersen JK. Oxidative stress in neurodegeneration: cause or consequence? Nature Medicine. 10: S18-25. PMID 15298006 DOI: 10.1038/Nrn1434 |
0.376 |
|
| 2004 |
Kumar MJ, Andersen JK. Perspectives on MAO-B in aging and neurological disease: where do we go from here? Molecular Neurobiology. 30: 77-89. PMID 15247489 DOI: 10.1385/Mn:30:1:077 |
0.402 |
|
| 2004 |
Kaur D, Andersen J. Does cellular iron dysregulation play a causative role in Parkinson's disease? Ageing Research Reviews. 3: 327-43. PMID 15231240 DOI: 10.1016/J.Arr.2004.01.003 |
0.44 |
|
| 2004 |
Peng J, Mao XO, Stevenson FF, Hsu M, Andersen JK. The herbicide paraquat induces dopaminergic nigral apoptosis through sustained activation of the JNK pathway. The Journal of Biological Chemistry. 279: 32626-32. PMID 15155744 DOI: 10.1074/Jbc.M404596200 |
0.424 |
|
| 2003 |
Andersen JK. Paraquat and iron exposure as possible synergistic environmental risk factors in Parkinson's disease. Neurotoxicity Research. 5: 307-13. PMID 14715449 DOI: 10.1007/Bf03033150 |
0.342 |
|
| 2003 |
Kumar MJ, Nicholls DG, Andersen JK. Oxidative alpha-ketoglutarate dehydrogenase inhibition via subtle elevations in monoamine oxidase B levels results in loss of spare respiratory capacity: implications for Parkinson's disease. The Journal of Biological Chemistry. 278: 46432-9. PMID 12963742 DOI: 10.1074/Jbc.M306378200 |
0.435 |
|
| 2003 |
Peng J, Andersen JK. The role of c-Jun N-terminal kinase (JNK) in Parkinson's disease. Iubmb Life. 55: 267-71. PMID 12880208 DOI: 10.1080/1521654031000121666 |
0.364 |
|
| 2003 |
Andersen J. Defects in dynein linked to motor neuron degeneration in mice. Science of Aging Knowledge Environment : Sage Ke. 2003: PE10. PMID 12844533 DOI: 10.1126/Sageke.2003.18.Pe10 |
0.308 |
|
| 2003 |
Kaur D, Yantiri F, Rajagopalan S, Kumar J, Mo JQ, Boonplueang R, Viswanath V, Jacobs R, Yang L, Beal MF, DiMonte D, Volitaskis I, Ellerby L, Cherny RA, Bush AI, ... Andersen JK, et al. Genetic or pharmacological iron chelation prevents MPTP-induced neurotoxicity in vivo: a novel therapy for Parkinson's disease. Neuron. 37: 899-909. PMID 12670420 DOI: 10.1016/S0896-6273(03)00126-0 |
0.639 |
|
| 2002 |
Kaur D, Andersen JK. Ironing out Parkinson's disease: is therapeutic treatment with iron chelators a real possibility? Aging Cell. 1: 17-21. PMID 12882349 DOI: 10.1046/J.1474-9728.2002.00001.X |
0.438 |
|
| 2002 |
Bharat S, Cochran BC, Hsu M, Liu J, Ames BN, Andersen JK. Pre-treatment with R-lipoic acid alleviates the effects of GSH depletion in PC12 cells: implications for Parkinson's disease therapy. Neurotoxicology. 23: 479-86. PMID 12428720 DOI: 10.1016/S0161-813X(02)00035-9 |
0.477 |
|
| 2002 |
Peng J, Wu Z, Wu Y, Hsu M, Stevenson FF, Boonplueang R, Roffler-Tarlov SK, Andersen JK. Inhibition of caspases protects cerebellar granule cells of the weaver mouse from apoptosis and improves behavioral phenotype. The Journal of Biological Chemistry. 277: 44285-91. PMID 12221097 DOI: 10.1074/Jbc.M207407200 |
0.329 |
|
| 2002 |
Bharath S, Hsu M, Kaur D, Rajagopalan S, Andersen JK. Glutathione, iron and Parkinson's disease. Biochemical Pharmacology. 64: 1037-48. PMID 12213603 DOI: 10.1016/S0006-2952(02)01174-7 |
0.504 |
|
| 2002 |
Jha N, Kumar MJ, Boonplueang R, Andersen JK. Glutathione decreases in dopaminergic PC12 cells interfere with the ubiquitin protein degradation pathway: relevance for Parkinson's disease? Journal of Neurochemistry. 80: 555-61. PMID 11841562 DOI: 10.1046/J.0022-3042.2001.00009.X |
0.63 |
|
| 2001 |
Andersen JK, Kumar J, Srinivas B, Kaur D, Hsu M, Rajagopalan S. The hunt for a cure for Parkinson's disease. Science of Aging Knowledge Environment : Sage Ke. 2001: re1. PMID 14602952 DOI: 10.1126/Sageke.2001.1.Re1 |
0.331 |
|
| 2001 |
Viswanath V, Wu Y, Boonplueang R, Chen S, Stevenson FF, Yantiri F, Yang L, Beal MF, Andersen JK. Caspase-9 activation results in downstream caspase-8 activation and bid cleavage in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 9519-28. PMID 11739563 DOI: 10.1523/Jneurosci.21-24-09519.2001 |
0.658 |
|
| 2001 |
Andersen JK. Genetically engineered mice and their use in aging research Applied Biochemistry and Biotechnology - Part B Molecular Biotechnology. 19: 45-57. PMID 11697220 DOI: 10.1385/Mb:19:1:045 |
0.3 |
|
| 2001 |
Rajagopalan S, Andersen JK. Alpha synuclein aggregation: Is it the toxic gain of function responsible for neurodegeneration in Parkinson's disease? Mechanisms of Ageing and Development. 122: 1499-1510. PMID 11511392 DOI: 10.1016/S0047-6374(01)00283-4 |
0.361 |
|
| 2001 |
Andersen JK. Does neuronal loss in Parkinson's disease involve programmed cell death? Bioessays. 23: 640-646. PMID 11462217 DOI: 10.1002/Bies.1089 |
0.453 |
|
| 2001 |
Yantiri F, Gasparyan A, Andersen JK. Glutamyl cysteine synthetase catalytic and regulatory subunits localize to dopaminergic nigral neurons as well as to astrocytes Journal of Neuroscience Research. 64: 203-206. PMID 11288148 DOI: 10.1002/Jnr.1066 |
0.446 |
|
| 2001 |
Andersen JK. Do alterations in glutathione and iron levels contribute to pathology associated with Parkinson's disease? Novartis Foundation Symposium. 235: 11-25. PMID 11280021 DOI: 10.1002/0470868694.Ch3 |
0.459 |
|
| 2001 |
Jiang D, Jha N, Boonplueang R, Andersen JK. Caspase 3 inhibition attenuates hydrogen peroxide-induced DNA fragmentation but not cell death in neuronal PC12 cells. Journal of Neurochemistry. 76: 1745-55. PMID 11259492 DOI: 10.1046/J.1471-4159.2001.00151.X |
0.556 |
|
| 2000 |
Andersen JK. What causes the build-up of ubiquitin-containing inclusions in Parkinson's disease? Mechanisms of Ageing and Development. 118: 15-22. PMID 10989121 DOI: 10.1016/S0047-6374(00)00150-0 |
0.456 |
|
| 2000 |
Jiang D, Akopian G, Ho YS, Walsh JP, Andersen JK. Chronic brain oxidation in a glutathione peroxidase knockout mouse model results in increased resistance to induced epileptic seizures. Experimental Neurology. 164: 257-68. PMID 10915565 DOI: 10.1006/Exnr.2000.7431 |
0.344 |
|
| 2000 |
Jha N, Jurma O, Lalli G, Liu Y, Pettus EH, Greenamyre JT, Liu RM, Forman HJ, Andersen JK. Glutathione depletion in PC12 results in selective inhibition of mitochondrial complex I activity. Implications for Parkinson's disease. The Journal of Biological Chemistry. 275: 26096-101. PMID 10846169 DOI: 10.1074/Jbc.M000120200 |
0.666 |
|
| 2000 |
Viswanath V, Wu Z, Fonck C, Wei Q, Boonplueang R, Andersen JK. Transgenic mice neuronally expressing baculoviral p35 are resistant to diverse types of induced apoptosis, including seizure-associated neurodegeneration. Proceedings of the National Academy of Sciences of the United States of America. 97: 2270-5. PMID 10681443 DOI: 10.1073/Pnas.030365297 |
0.628 |
|
| 1999 |
Yantiri F, Andersen JK. The role of iron in Parkinson disease and 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine toxicity Iubmb Life. 48: 139-141. PMID 10794588 DOI: 10.1080/713803493 |
0.462 |
|
| 1999 |
Kang Y, Viswanath V, Jha N, Qiao X, Mo JQ, Andersen JK. Brain γ-glutamyl cysteine synthetase (GCS) mRNA expression patterns correlate with regional-specific enzyme activities and glutathione levels Journal of Neuroscience Research. 58: 436-441. PMID 10518117 DOI: 10.1002/(Sici)1097-4547(19991101)58:3<436::Aid-Jnr9>3.0.Co;2-B |
0.675 |
|
| 1998 |
Andersen JK. Use of genetically engineered mice as models for exploring the role of oxidative stress in neurodegenerative diseases Frontiers in Bioscience : a Journal and Virtual Library. 3. PMID 9512453 DOI: 10.2741/A259 |
0.395 |
|
| 1997 |
Wei Q, Jurma OP, Andersen JK. Increased expression of monoamine oxidase-b results in enhanced neurite degeneration in methamphetamine-treated PC12 cells Journal of Neuroscience Research. 50: 618-626. PMID 9404723 DOI: 10.1002/(Sici)1097-4547(19971115)50:4<618::Aid-Jnr12>3.0.Co;2-Z |
0.352 |
|
| 1997 |
Jurma OP, Hom DG, Andersen JK. Decreased glutathione results in calcium-mediated cell death in PC12 Free Radical Biology and Medicine. 23: 1055-1066. PMID 9358249 DOI: 10.1016/S0891-5849(97)00134-2 |
0.43 |
|
| 1997 |
Kang Y, Qiao X, Jurma O, Knusel B, Andersen JK. Cloning/brain localization of mouse glutamylcysteine synthetase heavy chain mRNA Neuroreport. 8: 2053-2060. PMID 9223101 DOI: 10.1097/00001756-199705260-00049 |
0.35 |
|
| 1997 |
Hom DG, Jiang D, Hong EJ, Mo JQ, Andersen JK. Elevated expression of glutathione peroxidase in PC12 cells results in protection against methamphetamine but not MPTP toxicity. Brain Research. Molecular Brain Research. 46: 154-60. PMID 9191089 DOI: 10.1016/S0169-328X(96)00296-3 |
0.384 |
|
| 1996 |
Wei Q, Yeung M, Jurma OP, Andersen JK. Genetic elevation of monoamine oxidase levels in dopaminergic PC12 cells results in increased free radical damage and sensitivity to MPTP. Journal of Neuroscience Research. 46: 666-73. PMID 8978500 DOI: 10.1002/(Sici)1097-4547(19961215)46:6<666::Aid-Jnr3>3.0.Co;2-D |
0.364 |
|
| 1996 |
Andersen JK, Mo JQ, Hom DG, Lee FY, Harnish P, Hamill RW, McNeill TH. Effect of buthionine sulfoximine, a synthesis inhibitor of the antioxidant glutathione, on the murine nigrostriatal neurons. Journal of Neurochemistry. 67: 2164-71. PMID 8863527 DOI: 10.1046/J.1471-4159.1996.67052164.X |
0.41 |
|
| 1995 |
Mo JQ, Hom DG, Andersen JK. Decreases in protective enzymes correlates with increased oxidative damage in the aging mouse brain Mechanisms of Ageing and Development. 81: 73-82. PMID 8569282 DOI: 10.1016/0047-6374(95)01586-O |
0.371 |
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