Year |
Citation |
Score |
2023 |
Lane JR, Tata M, Yasmin R, Im H, Briles DE, Orihuela CJ. PspA-mediated aggregation protects against desiccation on fomites. Biorxiv : the Preprint Server For Biology. PMID 37808718 DOI: 10.1101/2023.09.27.559802 |
0.327 |
|
2023 |
Im H, Pearson ML, Martinez E, Cichos KH, Song X, Kruckow KL, Andrews RM, Ghanem ES, Orihuela CJ. Targeting NAD+ regeneration enhances antibiotic susceptibility of Streptococcus pneumoniae during invasive disease. Plos Biology. 21: e3002020. PMID 36928033 DOI: 10.1371/journal.pbio.3002020 |
0.303 |
|
2022 |
Lane JR, Tata M, Briles DE, Orihuela CJ. A Jack of All Trades: The Role of Pneumococcal Surface Protein A in the Pathogenesis of . Frontiers in Cellular and Infection Microbiology. 12: 826264. PMID 35186799 DOI: 10.3389/fcimb.2022.826264 |
0.325 |
|
2021 |
Park SS, Gonzalez-Juarbe N, Riegler AN, Im H, Hale Y, Platt MP, Croney C, Briles DE, Orihuela CJ. Streptococcus pneumoniae binds to host GAPDH on dying lung epithelial cells worsening secondary infection following influenza. Cell Reports. 35: 109267. PMID 34133917 DOI: 10.1016/j.celrep.2021.109267 |
0.302 |
|
2021 |
Park SS, Gonzalez-Juarbe N, Martínez E, Hale JY, Lin YH, Huffines JT, Kruckow KL, Briles DE, Orihuela CJ. Streptococcus pneumoniae Binds to Host Lactate Dehydrogenase via PspA and PspC To Enhance Virulence. Mbio. 12. PMID 33947761 DOI: 10.1128/mBio.00673-21 |
0.3 |
|
2020 |
Gonzalez-Juarbe N, Riegler AN, Jureka AS, Gilley RP, Brand JD, Trombley JE, Scott NR, Platt MP, Dube PH, Petit CM, Harrod KS, Orihuela CJ. Influenza-Induced Oxidative Stress Sensitizes Lung Cells to Bacterial-Toxin-Mediated Necroptosis. Cell Reports. 32: 108062. PMID 32846120 DOI: 10.1016/J.Celrep.2020.108062 |
0.378 |
|
2020 |
Beno SM, Riegler AN, Gilley RP, Brissac T, Wang Y, Kruckow KL, Jadapalli JK, Wright GM, Shenoy AT, Stoner SN, Restrepo MI, Deshane JS, Halade GV, Gonzalez-Juarbe N, Orihuela CJ. Necroptosis inhibition prevents long-term cardiac damage during pneumococcal pneumonia and invasive disease. The Journal of Infectious Diseases. PMID 32492702 DOI: 10.1093/Infdis/Jiaa295 |
0.393 |
|
2020 |
Morra CN, Orihuela CJ. Anatomical site-specific immunomodulation by bacterial biofilms. Current Opinion in Infectious Diseases. PMID 32304469 DOI: 10.1097/Qco.0000000000000643 |
0.437 |
|
2020 |
Orihuela CJ, Maus UA, Brown JS. Can animal models really teach us anything about pneumonia? Pro. The European Respiratory Journal. 55. PMID 31896678 DOI: 10.1183/13993003.01539-2019 |
0.312 |
|
2019 |
Riegler AN, Mann B, Orihuela CJ, Tuomanen E. Opening the OPK Assay Gatekeeper: Harnessing Multi-Modal Protection by Pneumococcal Vaccines. Pathogens (Basel, Switzerland). 8. PMID 31652741 DOI: 10.3390/Pathogens8040203 |
0.308 |
|
2019 |
Nahm MH, Brissac T, Kilian M, Vlach J, Orihuela CJ, Saad JS, Ganaie F. Pneumococci Can Become Virulent by Acquiring a New Capsule From Oral Streptococci. The Journal of Infectious Diseases. PMID 31605125 DOI: 10.1093/Infdis/Jiz456 |
0.356 |
|
2019 |
Wu X, Gordon O, Jiang W, Antezana BS, Angulo-Zamudio U, Del Rio C, Moller A, Brissac T, Tierney ARP, Warncke K, Orihuela CJ, Read TD, Vidal JE. Interaction between and generates OH radicals that rapidly kills strains. Journal of Bacteriology. PMID 31405914 DOI: 10.1128/Jb.00474-19 |
0.316 |
|
2019 |
Riegler AN, Brissac T, Gonzalez-Juarbe N, Orihuela CJ. Necroptotic Cell Death Promotes Adaptive Immunity Against Colonizing Pneumococci. Frontiers in Immunology. 10: 615. PMID 31019504 DOI: 10.3389/Fimmu.2019.00615 |
0.419 |
|
2019 |
Brissac T, Orihuela CJ. In Vitro Adhesion, Invasion, and Transcytosis of Streptococcus pneumoniae with Host Cells. Methods in Molecular Biology (Clifton, N.J.). 1968: 137-146. PMID 30929212 DOI: 10.1007/978-1-4939-9199-0_12 |
0.448 |
|
2019 |
Loughran AJ, Orihuela CJ, Tuomanen EI. : Invasion and Inflammation. Microbiology Spectrum. 7. PMID 30873934 DOI: 10.1128/Microbiolspec.Gpp3-0004-2018 |
0.397 |
|
2018 |
Shenoy AT, Beno SM, Brissac T, Bell JW, Novak L, Orihuela CJ. Severity and properties of cardiac damage caused by Streptococcus pneumoniae are strain dependent. Plos One. 13: e0204032. PMID 30216364 DOI: 10.1371/Journal.Pone.0204032 |
0.428 |
|
2018 |
Pajuelo D, Gonzalez-Juarbe N, Tak U, Sun J, Orihuela CJ, Niederweis M. NAD Depletion Triggers Macrophage Necroptosis, a Cell Death Pathway Exploited by Mycobacterium tuberculosis. Cell Reports. 24: 429-440. PMID 29996103 DOI: 10.1016/J.Celrep.2018.06.042 |
0.311 |
|
2018 |
Gonzalez-Juarbe N, Bradley KM, Riegler AN, Reyes LF, Brissac T, Park SS, Restrepo MI, Orihuela CJ. Bacterial Pore-Forming Toxins Promote the Activation of Caspases in Parallel to Necroptosis to Enhance Alarmin Release and Inflammation During Pneumonia. Scientific Reports. 8: 5846. PMID 29643440 DOI: 10.1038/S41598-018-24210-8 |
0.361 |
|
2018 |
Dela Cruz CS, Wunderink RG, Christiani DC, Cormier SA, Crothers K, Doerschuk CM, Evans SE, Goldstein DR, Khatri P, Kobzik L, Kolls JK, Levy BD, Metersky ML, Niederman MS, Nusrat R, ... Orihuela CJ, et al. Future Research Directions in Pneumonia: NHLBI Working Group Report. American Journal of Respiratory and Critical Care Medicine. PMID 29546996 DOI: 10.1164/Rccm.201801-0139Ws |
0.392 |
|
2018 |
Hakansson AP, Orihuela CJ, Bogaert D. Bacterial-Host Interactions: Physiology and Pathophysiology of Respiratory Infection. Physiological Reviews. 98: 781-811. PMID 29488821 DOI: 10.1152/Physrev.00040.2016 |
0.408 |
|
2017 |
Brissac T, Shenoy AT, Patterson LA, Orihuela CJ. Cell invasion and pyruvate oxidase derived H2O2 are critical for Streptococcus pneumoniae mediated cardiomyocyte killing. Infection and Immunity. PMID 29061707 DOI: 10.1128/Iai.00569-17 |
0.491 |
|
2017 |
Shenoy AT, Brissac T, Gilley RP, Kumar N, Wang Y, Gonzalez-Juarbe N, Hinkle WS, Daugherty SC, Shetty AC, Ott S, Tallon LJ, Deshane J, Tettelin H, Orihuela CJ. Streptococcus pneumoniae in the heart subvert the host response through biofilm-mediated resident macrophage killing. Plos Pathogens. 13: e1006582. PMID 28841717 DOI: 10.1371/Journal.Ppat.1006582 |
0.517 |
|
2017 |
Spencer BL, Shenoy AT, Orihuela CJ, Nahm MH. The pneumococcal serotype 15C capsule is partially O-acetylated and allows for limited evasion of PPV23-elicited anti-serotype 15B antibodies. Clinical and Vaccine Immunology : Cvi. PMID 28637806 DOI: 10.1128/Cvi.00099-17 |
0.308 |
|
2017 |
Reyes LF, Restrepo MI, Hinojosa CA, Soni NJ, Anzueto A, Babu BL, Gonzalez-Juarbe N, Rodriguez AH, Jimenez A, Chalmers JD, Aliberti S, Sibila O, Winter VT, Coalson JJ, Giavedoni LD, ... ... Orihuela CJ, et al. Severe Pneumococcal Pneumonia Causes Acute Cardiac Toxicity and Subsequent Cardiac Remodeling. American Journal of Respiratory and Critical Care Medicine. PMID 28614669 DOI: 10.1164/Rccm.201701-0104Oc |
0.395 |
|
2017 |
Spencer BL, Saad JS, Shenoy AT, Orihuela CJ, Nahm MH. Position of O-acetylation within the capsular repeat unit impacts the biological properties of pneumococcal serotypes 33A and 33F. Infection and Immunity. PMID 28438972 DOI: 10.1128/Iai.00132-17 |
0.313 |
|
2017 |
Lizcano A, Suresh Babu RA, Shenoy AT, Saville AM, Kumar N, D'Mello A, Hinojosa CA, Gilley RP, Segovia J, Mitchell TJ, Tettelin H, Orihuela CJ. Transcriptional organization of pneumococcal psrP-secY2A2 and impact of GtfA and GtfB deletion on PsrP-associated virulence properties. Microbes and Infection. PMID 28408270 DOI: 10.1016/J.Micinf.2017.04.001 |
0.802 |
|
2017 |
González-Juarbe N, Bradley KM, Shenoy AT, Gilley RP, Reyes LF, Hinojosa CA, Restrepo MI, Dube PH, Bergman MA, Orihuela CJ. Pore-forming toxin-mediated ion dysregulation leads to death receptor-independent necroptosis of lung epithelial cells during bacterial pneumonia. Cell Death and Differentiation. PMID 28387756 DOI: 10.1038/Cdd.2017.49 |
0.382 |
|
2017 |
Ray C, Shenoy AT, Orihuela CJ, González-Juarbe N. Killing of Serratia marcescens biofilms with chloramphenicol. Annals of Clinical Microbiology and Antimicrobials. 16: 19. PMID 28356113 DOI: 10.1186/S12941-017-0192-2 |
0.425 |
|
2017 |
González-Juarbe N, Shen H, Bergman MA, Orihuela CJ, Dube PH. YopE specific CD8+ T cells provide protection against systemic and mucosal Yersinia pseudotuberculosis infection. Plos One. 12: e0172314. PMID 28207901 DOI: 10.1371/Journal.Pone.0172314 |
0.349 |
|
2016 |
Reyes LF, Restrepo MI, Hinojosa CA, Soni NJ, Shenoy AT, Gilley RP, Gonzalez-Juarbe N, Noda JR, Winter VT, de la Garza MA, Shade RE, Coalson JJ, Giavedoni LD, Anzueto A, Orihuela CJ. A Non-Human Primate Model of Severe Pneumococcal Pneumonia. Plos One. 11: e0166092. PMID 27855182 DOI: 10.1371/Journal.Pone.0166092 |
0.34 |
|
2016 |
Shenoy AT, Orihuela CJ. Anatomical site-specific contributions of pneumococcal virulence determinants. Pneumonia (Nathan Qld.). 8. PMID 27635368 DOI: 10.1186/s41479-016-0007-9 |
0.336 |
|
2016 |
Blanchette KA, Shenoy AT, Milner J, Gilley RP, McClure E, Hinojosa CA, Kumar N, Daughtery SC, Tallon LJ, Ott S, King SJ, Ferreira DM, Gordon SB, Tettelin H, Orihuela CJ. Neuraminidase A exposed galactose promotes Streptococcus pneumoniae biofilm formation during colonization. Infection and Immunity. PMID 27481242 DOI: 10.1128/Iai.00277-16 |
0.788 |
|
2016 |
Shen H, Gonzalez-Juarbe N, Blanchette K, Crimmins G, Bergman MA, Isberg RR, Orihuela CJ, Dube PH. CD8+ T cells specific to a single Yersinia pseudotuberculosis epitope restrict bacterial replication in the liver but fail to provide sterilizing immunity. Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases. PMID 27268148 DOI: 10.1016/J.Meegid.2016.06.008 |
0.772 |
|
2016 |
Gilley RP, González-Juarbe N, Shenoy AT, Reyes LF, Dube PH, Restrepo MI, Orihuela CJ. Infiltrated Macrophages Die of Pneumolysin-Mediated Necroptosis following Pneumococcal Myocardial Invasion. Infection and Immunity. 84: 1457-69. PMID 26930705 DOI: 10.1128/Iai.00007-16 |
0.441 |
|
2016 |
Reyes L, Hinojosa C, Soni N, Orihuela C, Restrepo M. Pneumococcal pneumonia in baboons; a novel translational science model European Respiratory Journal. 48. DOI: 10.1183/13993003.Congress-2016.Oa4991 |
0.389 |
|
2015 |
González-Juarbe N, Gilley RP, Hinojosa CA, Bradley KM, Kamei A, Gao G, Dube PH, Bergman MA, Orihuela CJ. Pore-Forming Toxins Induce Macrophage Necroptosis during Acute Bacterial Pneumonia. Plos Pathogens. 11: e1005337. PMID 26659062 DOI: 10.1371/Journal.Ppat.1005337 |
0.385 |
|
2015 |
Hurez V, Dao V, Liu A, Pandeswara S, Gelfond J, Sun L, Bergman M, Orihuela CJ, Galvan V, Padrón Á, Drerup J, Liu Y, Hasty P, Sharp ZD, Curiel TJ. Chronic mTOR inhibition in mice with rapamycin alters T, B, myeloid, and innate lymphoid cells and gut flora and prolongs life of immune-deficient mice. Aging Cell. PMID 26315673 DOI: 10.1111/Acel.12380 |
0.362 |
|
2015 |
Brown AO, Orihuela CJ. Visualization of Streptococcus pneumoniae within Cardiac Microlesions and Subsequent Cardiac Remodeling. Journal of Visualized Experiments : Jove. PMID 25939051 DOI: 10.3791/52590 |
0.767 |
|
2015 |
Brown AO, Millett ER, Quint JK, Orihuela CJ. Cardiotoxicity during invasive pneumococcal disease. American Journal of Respiratory and Critical Care Medicine. 191: 739-45. PMID 25629643 DOI: 10.1164/Rccm.201411-1951Pp |
0.773 |
|
2015 |
González-Juarbe N, Mares CA, Hinojosa CA, Medina JL, Cantwell A, Dube PH, Orihuela CJ, Bergman MA. Requirement for Serratia marcescens cytolysin in a murine model of hemorrhagic pneumonia. Infection and Immunity. 83: 614-24. PMID 25422267 DOI: 10.1128/Iai.01822-14 |
0.442 |
|
2014 |
Gilley RP, Orihuela CJ. Pneumococci in biofilms are non-invasive: implications on nasopharyngeal colonization. Frontiers in Cellular and Infection Microbiology. 4: 163. PMID 25414838 DOI: 10.3389/Fcimb.2014.00163 |
0.506 |
|
2014 |
Brown AO, Mann B, Gao G, Hankins JS, Humann J, Giardina J, Faverio P, Restrepo MI, Halade GV, Mortensen EM, Lindsey ML, Hanes M, Happel KI, Nelson S, Bagby GJ, ... ... Orihuela CJ, et al. Streptococcus pneumoniae translocates into the myocardium and forms unique microlesions that disrupt cardiac function. Plos Pathogens. 10: e1004383. PMID 25232870 DOI: 10.1371/Journal.Ppat.1004383 |
0.768 |
|
2014 |
Hinojosa CA, Akula Suresh Babu R, Rahman MM, Fernandes G, Boyd AR, Orihuela CJ. Elevated A20 contributes to age-dependent macrophage dysfunction in the lungs. Experimental Gerontology. 54: 58-66. PMID 24440463 DOI: 10.1016/J.Exger.2014.01.007 |
0.332 |
|
2014 |
Faverio P, Aliberti S, Reyes L, Sibila O, Orihuela C, Brown A, Anzueto A, Chalmers J, Restrepo M. Antiplatelets Improve Survival Among Critically Ill Mechanically Ventilated Patients Chest. 146: 500A. DOI: 10.1378/Chest.1995211 |
0.712 |
|
2013 |
Blanchette-Cain K, Hinojosa CA, Akula Suresh Babu R, Lizcano A, Gonzalez-Juarbe N, Munoz-Almagro C, Sanchez CJ, Bergman MA, Orihuela CJ. Streptococcus pneumoniae biofilm formation is strain dependent, multifactorial, and associated with reduced invasiveness and immunoreactivity during colonization. Mbio. 4: e00745-13. PMID 24129258 DOI: 10.1128/Mbio.00745-13 |
0.801 |
|
2013 |
Iovino F, Orihuela CJ, Moorlag HE, Molema G, Bijlsma JJ. Interactions between blood-borne Streptococcus pneumoniae and the blood-brain barrier preceding meningitis. Plos One. 8: e68408. PMID 23874613 DOI: 10.1371/Journal.Pone.0068408 |
0.329 |
|
2012 |
Hinojosa CA, Mgbemena V, Van Roekel S, Austad SN, Miller RA, Bose S, Orihuela CJ. Enteric-delivered rapamycin enhances resistance of aged mice to pneumococcal pneumonia through reduced cellular senescence. Experimental Gerontology. 47: 958-65. PMID 22981852 DOI: 10.1016/J.Exger.2012.08.013 |
0.43 |
|
2012 |
Selva L, Ciruela P, Blanchette K, del Amo E, Pallares R, Orihuela CJ, Muñoz-Almagro C. Prevalence and clonal distribution of pcpA, psrP and Pilus-1 among pediatric isolates of Streptococcus pneumoniae. Plos One. 7: e41587. PMID 22848535 DOI: 10.1371/Journal.Pone.0041587 |
0.769 |
|
2012 |
Lizcano A, Sanchez CJ, Orihuela CJ. A role for glycosylated serine-rich repeat proteins in Gram-positive bacterial pathogenesis Molecular Oral Microbiology. 27: 257-269. PMID 22759311 DOI: 10.1111/J.2041-1014.2012.00653.X |
0.794 |
|
2012 |
Boyd AR, Hinojosa CA, Rodriguez PJ, Orihuela CJ. Impact of oral simvastatin therapy on acute lung injury in mice during pneumococcal pneumonia. Bmc Microbiology. 12: 73. PMID 22587610 DOI: 10.1186/1471-2180-12-73 |
0.354 |
|
2012 |
Boyd AR, Shivshankar P, Jiang S, Berton MT, Orihuela CJ. Age-related defects in TLR2 signaling diminish the cytokine response by alveolar macrophages during murine pneumococcal pneumonia. Experimental Gerontology. 47: 507-18. PMID 22548913 DOI: 10.1016/J.Exger.2012.04.004 |
0.362 |
|
2012 |
Blanchette KA, Orihuela CJ. Future perspective on host-pathogen interactions during bacterial biofilm formation within the nasopharynx. Future Microbiology. 7: 227-39. PMID 22324992 DOI: 10.2217/Fmb.11.160 |
0.799 |
|
2012 |
Andisi VF, Hinojosa CA, de Jong A, Kuipers OP, Orihuela CJ, Bijlsma JJ. Pneumococcal gene complex involved in resistance to extracellular oxidative stress. Infection and Immunity. 80: 1037-49. PMID 22215735 DOI: 10.1128/Iai.05563-11 |
0.316 |
|
2011 |
Sanchez CJ, Kumar N, Lizcano A, Shivshankar P, Dunning Hotopp JC, Jorgensen JH, Tettelin H, Orihuela CJ. Streptococcus pneumoniae in biofilms are unable to cause invasive disease due to altered virulence determinant production. Plos One. 6: e28738. PMID 22174882 DOI: 10.1371/Journal.Pone.0028738 |
0.806 |
|
2011 |
Sanchez CJ, Hurtgen BJ, Lizcano A, Shivshankar P, Cole GT, Orihuela CJ. Biofilm and planktonic pneumococci demonstrate disparate immunoreactivity to human convalescent sera. Bmc Microbiology. 11: 245. PMID 22047041 DOI: 10.1186/1471-2180-11-245 |
0.811 |
|
2011 |
Sanchez CJ, Hinojosa CA, Shivshankar P, Hyams C, Camberlein E, Brown JS, Orihuela CJ. Changes in capsular serotype alter the surface exposure of pneumococcal adhesins and impact virulence. Plos One. 6: e26587. PMID 22028914 DOI: 10.1371/Journal.Pone.0026587 |
0.54 |
|
2011 |
Shivshankar P, Boyd AR, Le Saux CJ, Yeh IT, Orihuela CJ. Cellular senescence increases expression of bacterial ligands in the lungs and is positively correlated with increased susceptibility to pneumococcal pneumonia. Aging Cell. 10: 798-806. PMID 21615674 DOI: 10.1111/J.1474-9726.2011.00720.X |
0.42 |
|
2010 |
Muñoz-Almagro C, Selva L, Sanchez CJ, Esteva C, de Sevilla MF, Pallares R, Orihuela CJ. PsrP, a protective pneumococcal antigen, is highly prevalent in children with pneumonia and is strongly associated with clonal type. Clinical and Vaccine Immunology : Cvi. 17: 1672-8. PMID 20861332 DOI: 10.1128/Cvi.00271-10 |
0.544 |
|
2010 |
Sanchez CJ, Shivshankar P, Stol K, Trakhtenbroit S, Sullam PM, Sauer K, Hermans PW, Orihuela CJ. The pneumococcal serine-rich repeat protein is an intra-species bacterial adhesin that promotes bacterial aggregation in vivo and in biofilms. Plos Pathogens. 6: e1001044. PMID 20714350 DOI: 10.1371/Journal.Ppat.1001044 |
0.634 |
|
2010 |
Paterson GK, Orihuela CJ. Pneumococci: immunology of the innate host response. Respirology (Carlton, Vic.). 15: 1057-63. PMID 20646240 DOI: 10.1111/J.1440-1843.2010.01814.X |
0.383 |
|
2010 |
Paterson GK, Orihuela CJ. Pneumococcal microbial surface components recognizing adhesive matrix molecules targeting of the extracellular matrix. Molecular Microbiology. 77: 1-5. PMID 20444102 DOI: 10.1111/J.1365-2958.2010.07190.X |
0.392 |
|
2010 |
Lizcano A, Chin T, Sauer K, Tuomanen EI, Orihuela CJ. Early biofilm formation on microtiter plates is not correlated with the invasive disease potential of Streptococcus pneumoniae. Microbial Pathogenesis. 48: 124-30. PMID 20096771 DOI: 10.1016/J.Micpath.2010.01.002 |
0.815 |
|
2010 |
Rosch JW, Boyd AR, Hinojosa E, Pestina T, Hu Y, Persons DA, Orihuela CJ, Tuomanen EI. Statins protect against fulminant pneumococcal infection and cytolysin toxicity in a mouse model of sickle cell disease. The Journal of Clinical Investigation. 120: 627-35. PMID 20093777 DOI: 10.1172/Jci39843 |
0.432 |
|
2009 |
Orihuela CJ. Role played by psrP-secY2A2 (accessory region 34) in the invasive disease potential of Streptococcus pneumoniae. The Journal of Infectious Diseases. 200: 1180-1; author reply. PMID 19723013 DOI: 10.1086/605649 |
0.323 |
|
2009 |
Li Z, Wang H, Xue L, Shin DM, Roopenian D, Xu W, Qi CF, Sangster MY, Orihuela CJ, Tuomanen E, Rehg JE, Cui X, Zhang Q, Morse HC, Morris SW. Emu-BCL10 mice exhibit constitutive activation of both canonical and noncanonical NF-kappaB pathways generating marginal zone (MZ) B-cell expansion as a precursor to splenic MZ lymphoma. Blood. 114: 4158-68. PMID 19696203 DOI: 10.1182/Blood-2008-12-192583 |
0.318 |
|
2009 |
Shivshankar P, Sanchez C, Rose LF, Orihuela CJ. The Streptococcus pneumoniae adhesin PsrP binds to Keratin 10 on lung cells. Molecular Microbiology. 73: 663-79. PMID 19627498 DOI: 10.1111/J.1365-2958.2009.06796.X |
0.586 |
|
2009 |
Hinojosa E, Boyd AR, Orihuela CJ. Age-associated inflammation and toll-like receptor dysfunction prime the lungs for pneumococcal pneumonia. The Journal of Infectious Diseases. 200: 546-54. PMID 19586419 DOI: 10.1086/600870 |
0.334 |
|
2009 |
Orihuela CJ, Mahdavi J, Thornton J, Mann B, Wooldridge KG, Abouseada N, Oldfield NJ, Self T, Ala'Aldeen DA, Tuomanen EI. Laminin receptor initiates bacterial contact with the blood brain barrier in experimental meningitis models. The Journal of Clinical Investigation. 119: 1638-46. PMID 19436113 DOI: 10.1172/Jci36759 |
0.391 |
|
2008 |
Rose L, Shivshankar P, Hinojosa E, Rodriguez A, Sanchez CJ, Orihuela CJ. Antibodies against PsrP, a novel Streptococcus pneumoniae adhesin, block adhesion and protect mice against pneumococcal challenge. The Journal of Infectious Diseases. 198: 375-83. PMID 18507531 DOI: 10.1086/589775 |
0.785 |
|
2007 |
Obert CA, Gao G, Sublett J, Tuomanen EI, Orihuela CJ. Assessment of molecular typing methods to determine invasiveness and to differentiate clones of Streptococcus pneumoniae. Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases. 7: 708-16. PMID 17768094 DOI: 10.1016/J.Meegid.2007.07.011 |
0.359 |
|
2007 |
Embry A, Hinojosa E, Orihuela CJ. Regions of Diversity 8, 9 and 13 contribute to Streptococcus pneumoniae virulence. Bmc Microbiology. 7: 80. PMID 17723151 DOI: 10.1186/1471-2180-7-80 |
0.322 |
|
2006 |
Fillon S, Soulis K, Rajasekaran S, Benedict-Hamilton H, Radin JN, Orihuela CJ, El Kasmi KC, Murti G, Kaushal D, Gaber MW, Weber JR, Murray PJ, Tuomanen EI. Platelet-activating factor receptor and innate immunity: uptake of gram-positive bacterial cell wall into host cells and cell-specific pathophysiology. Journal of Immunology (Baltimore, Md. : 1950). 177: 6182-91. PMID 17056547 DOI: 10.4049/Jimmunol.177.9.6182 |
0.423 |
|
2006 |
Obert C, Sublett J, Kaushal D, Hinojosa E, Barton T, Tuomanen EI, Orihuela CJ. Identification of a Candidate Streptococcus pneumoniae core genome and regions of diversity correlated with invasive pneumococcal disease. Infection and Immunity. 74: 4766-77. PMID 16861665 DOI: 10.1128/Iai.00316-06 |
0.396 |
|
2006 |
Orihuela CJ, Fillon S, Smith-Sielicki SH, El Kasmi KC, Gao G, Soulis K, Patil A, Murray PJ, Tuomanen EI. Cell wall-mediated neuronal damage in early sepsis. Infection and Immunity. 74: 3783-9. PMID 16790750 DOI: 10.1128/Iai.00022-06 |
0.345 |
|
2006 |
Mann B, Orihuela C, Antikainen J, Gao G, Sublett J, Korhonen TK, Tuomanen E. Multifunctional role of choline binding protein G in pneumococcal pathogenesis. Infection and Immunity. 74: 821-9. PMID 16428724 DOI: 10.1128/Iai.74.2.821-829.2006 |
0.395 |
|
2006 |
Radin JN, Orihuela CJ, Murti G, Guglielmo C, Murray PJ, Tuomanen EI. Erratum: β-arrestin 1 participates in platelet-activating factor receptor-mediated endocytosis of Streptococcus pneumoniae (Infection and Immunity (2005) 73, 12 (7827-7835)) Infection and Immunity. 74: 3078-3078. DOI: 10.1128/Iai.74.5.3078.2006 |
0.307 |
|
2006 |
Orihuela CJ, Tuomanen EI. Models of pneumococcal disease Drug Discovery Today: Disease Models. 3: 69-75. DOI: 10.1016/J.Ddmod.2006.03.001 |
0.374 |
|
2005 |
Sandgren A, Albiger B, Orihuela CJ, Tuomanen E, Normark S, Henriques-Normark B. Virulence in mice of pneumococcal clonal types with known invasive disease potential in humans. The Journal of Infectious Diseases. 192: 791-800. PMID 16088828 DOI: 10.1086/432513 |
0.39 |
|
2005 |
Kadurugamuwa JL, Modi K, Yu J, Francis KP, Orihuela C, Tuomanen E, Purchio AF, Contag PR. Noninvasive monitoring of pneumococcal meningitis and evaluation of treatment efficacy in an experimental mouse model. Molecular Imaging. 4: 137-142. DOI: 10.1162/15353500200505106 |
0.326 |
|
2004 |
Orihuela CJ, Gao G, Francis KP, Yu J, Tuomanen EI. Tissue-specific contributions of pneumococcal virulence factors to pathogenesis. The Journal of Infectious Diseases. 190: 1661-9. PMID 15478073 DOI: 10.1086/424596 |
0.418 |
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2004 |
Orihuela CJ, Radin JN, Sublett JE, Gao G, Kaushal D, Tuomanen EI. Microarray analysis of pneumococcal gene expression during invasive disease. Infection and Immunity. 72: 5582-96. PMID 15385455 DOI: 10.1128/Iai.72.10.5582-5596.2004 |
0.379 |
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2003 |
Orihuela CJ, Gao G, McGee M, Yu J, Francis KP, Tuomanen E. Organ-specific models of Streptococcus pneumoniae disease. Scandinavian Journal of Infectious Diseases. 35: 647-52. PMID 14620149 DOI: 10.1080/00365540310015854 |
0.422 |
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2001 |
Orihuela CJ, Mills J, Robb CW, Wilson CJ, Watson DA, Niesel DW. Streptococcus pneumoniae PstS production is phosphate responsive and enhanced during growth in the murine peritoneal cavity. Infection and Immunity. 69: 7565-71. PMID 11705934 DOI: 10.1128/Iai.69.12.7565-7571.2001 |
0.674 |
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2001 |
Robb CW, Orihuela CJ, Ekkelenkamp MB, Niesel DW. Identification and characterization of an in vivo regulated D15/Oma87 homologue in Shigella flexneri using differential display polymerase chain reaction. Gene. 262: 169-77. PMID 11179681 DOI: 10.1016/S0378-1119(00)00537-0 |
0.644 |
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2000 |
Orihuela CJ, Janssen R, Robb CW, Watson DA, Niesel DW. Peritoneal culture alters Streptococcus pneumoniae protein profiles and virulence properties. Infection and Immunity. 68: 6082-6. PMID 10992528 DOI: 10.1128/Iai.68.10.6082-6086.2000 |
0.658 |
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