| Year |
Citation |
Score |
| 2023 |
Galaj E, Barrera ED, Persaud K, Nisanov R, Vashisht A, Goldberg H, Patel N, Lenhard H, You ZB, Gardner EL, Ranaldi R. The impact of heroin self-administration and environmental enrichment on ventral tegmental CRF1 receptor expression. The International Journal of Neuropsychopharmacology. PMID 37864842 DOI: 10.1093/ijnp/pyad060 |
0.315 |
|
| 2023 |
Froimowitz M, Taboada R, Poulos ZJ, Rainone DJ, Imler GH, Gardner EL, Kelley CJ. Chiral Resolution of the Enantiomers of the Slow-Onset Dopamine Reuptake Inhibitor CTDP-32476 and Their Activities. Acs Omega. 8: 35738-35745. PMID 37810691 DOI: 10.1021/acsomega.3c02997 |
0.352 |
|
| 2022 |
He Y, Madeo G, Liang Y, Zhang C, Hempel B, Liu X, Mu L, Liu S, Bi GH, Galaj E, Zhang HY, Shen H, McDevitt RA, Gardner EL, Liu QS, et al. A red nucleus-VTA glutamate pathway underlies exercise reward and the therapeutic effect of exercise on cocaine use. Science Advances. 8: eabo1440. PMID 36054363 DOI: 10.1126/sciadv.abo1440 |
0.457 |
|
| 2022 |
Galaj E, Hempel B, Moore A, Klein B, Bi GH, Gardner EL, Seltzman HH, Xi ZX. Therapeutic potential of PIMSR, a novel CB1 receptor neutral antagonist, for cocaine use disorder: evidence from preclinical research. Translational Psychiatry. 12: 286. PMID 35851573 DOI: 10.1038/s41398-022-02059-w |
0.564 |
|
| 2022 |
Yang HJ, Hempel BJ, Bi GH, He Y, Zhang HY, Gardner EL, Xi ZX. Elevation of extracellular glutamate by blockade of astrocyte glutamate transporters inhibits cocaine reinforcement in rats via a NMDA-GluN2B receptor mechanism. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 35091501 DOI: 10.1523/JNEUROSCI.1432-21.2022 |
0.548 |
|
| 2022 |
You ZB, Gardner EL, Galaj E, Moore AR, Buck T, Jordan CJ, Humburg BA, Bi GH, Xi ZX, Leggio L. Involvement of the ghrelin system in the maintenance of oxycodone self-administration: converging evidence from endocrine, pharmacologic and transgenic approaches. Molecular Psychiatry. PMID 35064236 DOI: 10.1038/s41380-022-01438-5 |
0.378 |
|
| 2021 |
You ZB, Galaj E, Alén F, Wang B, Bi GH, Moore AR, Buck T, Crissman M, Pari S, Xi ZX, Leggio L, Wise RA, Gardner EL. Involvement of the ghrelin system in the maintenance and reinstatement of cocaine-motivated behaviors: a role of adrenergic action at peripheral β1 receptors. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 34923576 DOI: 10.1038/s41386-021-01249-2 |
0.52 |
|
| 2021 |
He XH, Galaj E, Bi GH, He Y, Hempel B, Wang YL, Gardner EL, Xi ZX. β-caryophyllene, an FDA-Approved Food Additive, Inhibits Methamphetamine-Taking and Methamphetamine-Seeking Behaviors Possibly CB2 and Non-CB2 Receptor Mechanisms. Frontiers in Pharmacology. 12: 722476. PMID 34566647 DOI: 10.3389/fphar.2021.722476 |
0.469 |
|
| 2021 |
Zhang HY, De Biase L, Chandra R, Shen H, Liu QR, Gardner E, Lobo MK, Xi ZX. Repeated cocaine administration upregulates CB receptor expression in striatal medium-spiny neurons that express dopamine D receptors in mice. Acta Pharmacologica Sinica. PMID 34316031 DOI: 10.1038/s41401-021-00712-6 |
0.459 |
|
| 2020 |
Li X, Hempel BJ, Yang HJ, Han X, Bi GH, Gardner EL, Xi ZX. Dissecting the role of CB and CB receptors in cannabinoid reward versus aversion using transgenic CB- and CB-knockout mice. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. PMID 33334652 DOI: 10.1016/j.euroneuro.2020.11.019 |
0.302 |
|
| 2020 |
Galaj E, Bi GH, Moore A, Chen K, He Y, Gardner E, Xi ZX. Beta-caryophyllene inhibits cocaine self-administration by activation of PPARα and PPARγ: repurposing a FDA-approved food additive for cocaine use disorder. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 33069159 DOI: 10.1038/s41386-020-00885-4 |
0.537 |
|
| 2020 |
Schweppe CA, Burzynski C, Jayanthi S, Ladenheim B, Cadet JL, Gardner EL, Xi ZX, van Praag H, Newman AH, Keck TM. Neurochemical and behavioral comparisons of contingent and non-contingent methamphetamine exposure following binge or yoked long-access self-administration paradigms. Psychopharmacology. PMID 32388619 DOI: 10.1007/S00213-020-05513-Z |
0.358 |
|
| 2020 |
Galaj E, Bi G, Gardner E, Xi Z. Beta‐caryophyllene, a Volatile Phytocannabinoid, Attenuates Cocaine Self‐administration and Relapse in Rats The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.00005 |
0.534 |
|
| 2019 |
He Y, Galaj E, Bi GH, Wang XF, Gardner E, Xi ZX. Beta-caryophyllene, a dietary terpenoid, inhibits nicotine-taking and nicotine-seeking in rodents. British Journal of Pharmacology. PMID 31883107 DOI: 10.1111/Bph.14969 |
0.33 |
|
| 2019 |
Wang XF, Galaj E, Bi GH, Zhang C, He Y, Zhan J, Bauman M, Gardner EL, Xi ZX. Different receptor mechanisms underlying phytocannabinoid- versus synthetic cannabinoid-induced tetrad effects: Opposite roles of CB1/CB2 versus GPR55 receptors. British Journal of Pharmacology. PMID 31877572 DOI: 10.1111/Bph.14958 |
0.343 |
|
| 2019 |
Xi ZX, Muldoon P, Wang XF, Bi GH, Damaj MI, Lichtman AH, Pertwee RG, Gardner EL. Δ -Tetrahydrocannabivarin has potent anti-nicotine effects in multiple rodent models of nicotine dependence. British Journal of Pharmacology. PMID 31454413 DOI: 10.1111/Bph.14844 |
0.428 |
|
| 2019 |
Spiller KJ, Bi GH, He Y, Galaj E, Gardner EL, Xi ZX. Cannabinoid CB and CB receptor mechanisms underlie cannabis reward and aversion in rats. British Journal of Pharmacology. PMID 30767215 DOI: 10.1111/Bph.14625 |
0.669 |
|
| 2018 |
You ZB, Bi GH, Galaj E, Kumar V, Cao J, Gadiano A, Rais R, Slusher BS, Gardner EL, Xi ZX, Newman AH. Dopamine DR antagonist VK4-116 attenuates oxycodone self-administration and reinstatement without compromising its antinociceptive effects. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30555159 DOI: 10.1038/S41386-018-0284-5 |
0.473 |
|
| 2018 |
Uhl GR, Martinez MJ, Paik P, Sulima A, Bi GH, Iyer MR, Gardner E, Rice KC, Xi ZX. Cocaine reward is reduced by decreased expression of receptor-type protein tyrosine phosphatase D (PTPRD) and by a novel PTPRD antagonist. Proceedings of the National Academy of Sciences of the United States of America. PMID 30348770 DOI: 10.1073/Pnas.1720446115 |
0.586 |
|
| 2018 |
Gao JT, Jordan C, Bi GH, He Y, Yang HJ, Gardner EL, Xi ZX. Deletion of the type 2 metabotropic glutamate receptor increases heroin abuse vulnerability in transgenic rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30283001 DOI: 10.1038/S41386-018-0231-5 |
0.462 |
|
| 2018 |
Alen F, Decara J, Brunori G, You ZB, Bühler KM, López-Moreno JA, Cippitelli A, Pavon J, Suárez J, Gardner EL, de la Torre R, Ciccocioppo R, Serrano A, de Fonseca FR. PPARα/CB1 receptor dual ligands as a novel therapy for alcohol use disorder: evaluation of a novel oleic acid conjugate in preclinical rat models. Biochemical Pharmacology. PMID 30195735 DOI: 10.1016/J.Bcp.2018.09.008 |
0.336 |
|
| 2018 |
Zhan J, Jordan CJ, Bi GH, He XH, Gardner EL, Wang YL, Xi ZX. Genetic deletion of the dopamine D3 receptor increases vulnerability to heroin in mice. Neuropharmacology. PMID 30138692 DOI: 10.1016/J.Neuropharm.2018.08.016 |
0.475 |
|
| 2018 |
He XH, Jordan CJ, Vemuri K, Bi GH, Zhan J, Gardner EL, Makriyannis A, Wang YL, Xi ZX. Cannabinoid CB receptor neutral antagonist AM4113 inhibits heroin self-administration without depressive side effects in rats. Acta Pharmacologica Sinica. PMID 29967454 DOI: 10.1038/S41401-018-0059-X |
0.546 |
|
| 2018 |
Rice OV, Ashby CR, Dixon C, Laurenzo W, Hayden J, Song R, Li J, Tiwari AK, Gardner EL. Selective Dopamine D Receptor Antagonism Significantly Attenuates Stress-Induced Immobility in a Rat Model of Post-Traumatic Stress Disorder. Synapse (New York, N.Y.). PMID 29704283 DOI: 10.1002/Syn.22035 |
0.394 |
|
| 2018 |
Li X, Peng XQ, Jordan CJ, Li J, Bi GH, He Y, Yang HJ, Zhang HY, Gardner EL, Xi ZX. mGluR5 antagonism inhibits cocaine reinforcement and relapse by elevation of extracellular glutamate in the nucleus accumbens via a CB1 receptor mechanism. Scientific Reports. 8: 3686. PMID 29487381 DOI: 10.1038/S41598-018-22087-1 |
0.582 |
|
| 2018 |
Zallar LJ, Tunstall BJ, Richie CT, Zhang YJ, You ZB, Gardner EL, Heilig M, Pickel J, Koob GF, Vendruscolo LF, Harvey BK, Leggio L. Development and initial characterization of a novel ghrelin receptor CRISPR/Cas9 knockout wistar rat model. International Journal of Obesity (2005). PMID 29453460 DOI: 10.1038/S41366-018-0013-5 |
0.365 |
|
| 2017 |
Liu QR, Canseco-Alba A, Zhang HY, Tagliaferro P, Chung M, Dennis E, Sanabria B, Schanz N, Escosteguy-Neto JC, Ishiguro H, Lin Z, Sgro S, Leonard CM, Santos-Junior JG, Gardner EL, et al. Cannabinoid type 2 receptors in dopamine neurons inhibits psychomotor behaviors, alters anxiety, depression and alcohol preference. Scientific Reports. 7: 17410. PMID 29234141 DOI: 10.1038/S41598-017-17796-Y |
0.412 |
|
| 2017 |
Han X, He Y, Bi GH, Zhang HY, Song R, Liu QR, Egan JM, Gardner EL, Li J, Xi ZX. CB1 Receptor Activation on VgluT2-Expressing Glutamatergic Neurons Underlies Δ(9)-Tetrahydrocannabinol (Δ(9)-THC)-Induced Aversive Effects in Mice. Scientific Reports. 7: 12315. PMID 28951549 DOI: 10.1038/S41598-017-12399-Z |
0.398 |
|
| 2017 |
You ZB, Gao JT, Bi GH, He Y, Boateng C, Cao J, Gardner EL, Newman AH, Xi ZX. The novel dopamine D3 receptor antagonists/partial agonists CAB2-015 and BAK4-54 inhibit oxycodone-taking and oxycodone-seeking behavior in rats. Neuropharmacology. PMID 28888944 DOI: 10.1016/J.Neuropharm.2017.09.007 |
0.485 |
|
| 2017 |
Zhang HY, Bi GH, Yang HJ, He Y, Xue G, Cao JJ, Tanda G, Gardner EL, Newman AH, Xi ZX. The Novel Modafinil Analog, JJC8-016, as a Potential Cocaine Abuse Pharmacotherapeutic. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28266501 DOI: 10.1038/Npp.2017.41 |
0.606 |
|
| 2016 |
Xi ZX, Song R, Li X, Lu GY, Peng XQ, He Y, Bi GH, Shen P, Yang HJ, Zhang H, Li J, Froimowitz M, Gardner EL. CTDP-32,476: A Promising Agonist Therapy for Treatment of Cocaine Addiction. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 27534265 DOI: 10.1038/Npp.2016.155 |
0.62 |
|
| 2016 |
Kumar V, Bonifazi A, Ellenberger MP, Keck TM, Pommier E, Rais R, Slusher BS, Gardner E, You ZB, Xi ZX, Newman AH. Highly Selective Dopamine D3 Receptor (D3R) Antagonists and Partial Agonists Based on Eticlopride and the D3R Crystal Structure: New Leads for Opioid Dependence Treatment. Journal of Medicinal Chemistry. PMID 27508895 DOI: 10.1021/Acs.Jmedchem.6B00860 |
0.454 |
|
| 2016 |
Fraser KM, Haight JL, Gardner EL, Flagel SB. Examining the role of dopamine D2 and D3 receptors in Pavlovian conditioned approach behaviors. Behavioural Brain Research. PMID 26909847 DOI: 10.1016/J.Bbr.2016.02.022 |
0.415 |
|
| 2016 |
Zhang HY, Gao M, Shen H, Bi GH, Yang HJ, Liu QR, Wu J, Gardner EL, Bonci A, Xi ZX. Expression of functional cannabinoid CB2 receptor in VTA dopamine neurons in rats. Addiction Biology. PMID 26833913 DOI: 10.1111/Adb.12367 |
0.53 |
|
| 2016 |
Gardner EL, Bi G, Thakur G, Makriyannis A, Seltzman HH, He X, Xi Z. PM288. Preclinical Evaluation of Neutral Cannabinoid CB1 Receptor Antagonists and Cannabinoid CB1 Receptor Negative Allosteric Modulators for Treating Drug Addiction The International Journal of Neuropsychopharmacology. 19: 3-3. DOI: 10.1093/Ijnp/Pyw041.288 |
0.35 |
|
| 2015 |
Blum K, Thanos PK, Oscar-Berman M, Febo M, Baron D, Badgaiyan RD, Gardner E, Demetrovics Z, Fahlke C, Haberstick BC, Dushaj K, Gold MS. Dopamine in the Brain: Hypothesizing Surfeit or Deficit Links to Reward and Addiction. Journal of Reward Deficiency Syndrome. 1: 95-104. PMID 27398406 DOI: 10.17756/jrds.2015-016 |
0.465 |
|
| 2015 |
Ashby CR, Rice OV, Heidbreder CA, Gardner EL. The selective dopamine D3 receptor antagonist SB-277011A significantly accelerates extinction to environmental cues associated with cocaine-induced place preference in male sprague-dawley rats. Synapse (New York, N.Y.). PMID 26138517 DOI: 10.1002/Syn.21839 |
0.542 |
|
| 2015 |
Ashby CR, Rice OV, Heidbreder CA, Gardner EL. The selective dopamine D₃ receptor antagonist SB-277011A attenuates drug- or food-deprivation reactivation of expression of conditioned place preference for cocaine in male Sprague-Dawley rats. Synapse (New York, N.Y.). 69: 336-44. PMID 25851636 DOI: 10.1002/Syn.21820 |
0.594 |
|
| 2015 |
Rice OV, Schonhar CA, Gaál J, Gardner EL, Ashby CR. The selective dopamine D₃ receptor antagonist SB-277011-A significantly decreases binge-like consumption of ethanol in C57BL/J6 mice. Synapse (New York, N.Y.). 69: 295-8. PMID 25764479 DOI: 10.1002/Syn.21816 |
0.449 |
|
| 2015 |
Wang XF, Bi GH, He Y, Yang HJ, Gao JT, Okunola-Bakare OM, Slack RD, Gardner EL, Xi ZX, Newman AH. R-modafinil attenuates nicotine-taking and nicotine-seeking behavior in alcohol-preferring rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 1762-71. PMID 25613829 DOI: 10.1038/Npp.2015.24 |
0.397 |
|
| 2015 |
Zhang HY, Bi GH, Li X, Li J, Qu H, Zhang SJ, Li CY, Onaivi ES, Gardner EL, Xi ZX, Liu QR. Species differences in cannabinoid receptor 2 and receptor responses to cocaine self-administration in mice and rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 1037-51. PMID 25374096 DOI: 10.1038/Npp.2014.297 |
0.5 |
|
| 2014 |
Zhang HY, Gao M, Liu QR, Bi GH, Li X, Yang HJ, Gardner EL, Wu J, Xi ZX. Cannabinoid CB2 receptors modulate midbrain dopamine neuronal activity and dopamine-related behavior in mice. Proceedings of the National Academy of Sciences of the United States of America. 111: E5007-15. PMID 25368177 DOI: 10.1073/Pnas.1413210111 |
0.445 |
|
| 2014 |
Song R, Bi GH, Zhang HY, Yang RF, Gardner EL, Li J, Xi ZX. Blockade of D3 receptors by YQA14 inhibits cocaine's rewarding effects and relapse to drug-seeking behavior in rats. Neuropharmacology. 77: 398-405. PMID 24176392 DOI: 10.1016/J.Neuropharm.2013.10.010 |
0.637 |
|
| 2014 |
Keck TM, Zou MF, Bi GH, Zhang HY, Wang XF, Yang HJ, Srivastava R, Gardner EL, Xi ZX, Newman AH. A novel mGluR5 antagonist, MFZ 10-7, inhibits cocaine-taking and cocaine-seeking behavior in rats. Addiction Biology. 19: 195-209. PMID 24001208 DOI: 10.1111/Adb.12086 |
0.605 |
|
| 2014 |
Gardner EL, Zhang H, Peng X, Su R, Yang R, Li J, Xi Z, Song R. Dopamine D3 receptors underlie cocaine-induced conditioned place preference in mice Drug and Alcohol Dependence. 140: e67. DOI: 10.1016/J.Drugalcdep.2014.02.201 |
0.55 |
|
| 2013 |
Song R, Zhang HY, Peng XQ, Su RB, Yang RF, Li J, Xi ZX, Gardner EL. Dopamine D(3) receptor deletion or blockade attenuates cocaine-induced conditioned place preference in mice. Neuropharmacology. 72: 82-7. PMID 23643749 DOI: 10.1016/J.Neuropharm.2013.04.042 |
0.59 |
|
| 2013 |
Keck TM, Yang HJ, Bi GH, Huang Y, Zhang HY, Srivastava R, Gardner EL, Newman AH, Xi ZX. Fenobam sulfate inhibits cocaine-taking and cocaine-seeking behavior in rats: implications for addiction treatment in humans. Psychopharmacology. 229: 253-65. PMID 23615919 DOI: 10.1007/S00213-013-3106-9 |
0.594 |
|
| 2013 |
Rice OV, Heidbreder CA, Gardner EL, Schonhar CD, Ashby CR. The selective D₃ receptor antagonist SB-277011A attenuates morphine-triggered reactivation of expression of cocaine-induced conditioned place preference. Synapse (New York, N.Y.). 67: 469-75. PMID 23404528 DOI: 10.1002/Syn.21653 |
0.577 |
|
| 2013 |
Xi ZX, Li X, Li J, Peng XQ, Song R, Gaál J, Gardner EL. Blockade of dopamine D3 receptors in the nucleus accumbens and central amygdala inhibits incubation of cocaine craving in rats. Addiction Biology. 18: 665-77. PMID 22913325 DOI: 10.1111/J.1369-1600.2012.00486.X |
0.611 |
|
| 2013 |
Yang H, Bi G, Zhang H, Peng X, Gardner EL, Xi Z. The Anticonvulsant Tiagabine Inhibits Cocaine' s Rewarding Effects, but has No Effect on Reinstatement of Cocaine-Seeking Behavior in Rats Biochemical Pharmacology. 2013: 1-6. DOI: 10.4172/2167-0501.S1-005 |
0.594 |
|
| 2012 |
Song R, Zhang HY, Li X, Bi GH, Gardner EL, Xi ZX. Increased vulnerability to cocaine in mice lacking dopamine D3 receptors. Proceedings of the National Academy of Sciences of the United States of America. 109: 17675-80. PMID 23045656 DOI: 10.1073/Pnas.1205297109 |
0.582 |
|
| 2012 |
Blum K, Gardner E, Oscar-Berman M, Gold M. "Liking" and "wanting" linked to Reward Deficiency Syndrome (RDS): hypothesizing differential responsivity in brain reward circuitry. Current Pharmaceutical Design. 18: 113-8. PMID 22236117 DOI: 10.2174/138161212798919110 |
0.484 |
|
| 2012 |
Srivastava R, Xi ZX, Gardner EL. Cocaine-taking and cocaine-seeking behaviors in rats remain stable after systemic administration of GYKI 52466: a non-competitive AMPA receptor antagonist. Neuroscience Letters. 508: 106-9. PMID 22206835 DOI: 10.1016/J.Neulet.2011.12.028 |
0.613 |
|
| 2012 |
Song R, Yang RF, Wu N, Su RB, Li J, Peng XQ, Li X, Gaál J, Xi ZX, Gardner EL. YQA14: a novel dopamine D3 receptor antagonist that inhibits cocaine self-administration in rats and mice, but not in D3 receptor-knockout mice. Addiction Biology. 17: 259-73. PMID 21507153 DOI: 10.1111/J.1369-1600.2011.00317.X |
0.525 |
|
| 2011 |
Xi ZX, Peng XQ, Li X, Song R, Zhang HY, Liu QR, Yang HJ, Bi GH, Li J, Gardner EL. Brain cannabinoid CB₂ receptors modulate cocaine's actions in mice. Nature Neuroscience. 14: 1160-6. PMID 21785434 DOI: 10.1038/Nn.2874 |
0.606 |
|
| 2011 |
Gardner EL. Addiction and brain reward and antireward pathways. Advances in Psychosomatic Medicine. 30: 22-60. PMID 21508625 DOI: 10.1159/000324065 |
0.5 |
|
| 2011 |
Higley AE, Kiefer SW, Li X, Gaál J, Xi ZX, Gardner EL. Dopamine D(3) receptor antagonist SB-277011A inhibits methamphetamine self-administration and methamphetamine-induced reinstatement of drug-seeking in rats. European Journal of Pharmacology. 659: 187-92. PMID 21466803 DOI: 10.1016/J.Ejphar.2011.02.046 |
0.552 |
|
| 2011 |
Higley AE, Spiller K, Grundt P, Newman AH, Kiefer SW, Xi ZX, Gardner EL. PG01037, a novel dopamine D3 receptor antagonist, inhibits the effects of methamphetamine in rats. Journal of Psychopharmacology (Oxford, England). 25: 263-73. PMID 20142301 DOI: 10.1177/0269881109358201 |
0.772 |
|
| 2010 |
Peng XQ, Xi ZX, Li X, Spiller K, Li J, Chun L, Wu KM, Froimowitz M, Gardner EL. Is slow-onset long-acting monoamine transport blockade to cocaine as methadone is to heroin? Implication for anti-addiction medications. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 2564-78. PMID 20827272 DOI: 10.1038/Npp.2010.133 |
0.779 |
|
| 2010 |
Li X, Li J, Gardner EL, Xi ZX. Activation of mGluR7s inhibits cocaine-induced reinstatement of drug-seeking behavior by a nucleus accumbens glutamate-mGluR2/3 mechanism in rats. Journal of Neurochemistry. 114: 1368-80. PMID 20534005 DOI: 10.1111/J.1471-4159.2010.06851.X |
0.609 |
|
| 2010 |
Xi ZX, Li X, Peng XQ, Li J, Chun L, Gardner EL, Thomas AG, Slusher BS, Ashby CR. Inhibition of NAALADase by 2-PMPA attenuates cocaine-induced relapse in rats: a NAAG-mGluR2/3-mediated mechanism. Journal of Neurochemistry. 112: 564-76. PMID 19895667 DOI: 10.1111/J.1471-4159.2009.06478.X |
0.611 |
|
| 2010 |
Peng XQ, Li J, Gardner EL, Ashby CR, Thomas A, Wozniak K, Slusher BS, Xi ZX. Oral administration of the NAALADase inhibitor GPI-5693 attenuates cocaine-induced reinstatement of drug-seeking behavior in rats. European Journal of Pharmacology. 627: 156-61. PMID 19887067 DOI: 10.1016/J.Ejphar.2009.10.062 |
0.605 |
|
| 2010 |
Xi ZX, Kiyatkin M, Li X, Peng XQ, Wiggins A, Spiller K, Li J, Gardner EL. N-acetylaspartylglutamate (NAAG) inhibits intravenous cocaine self-administration and cocaine-enhanced brain-stimulation reward in rats. Neuropharmacology. 58: 304-13. PMID 19559037 DOI: 10.1016/J.Neuropharm.2009.06.016 |
0.797 |
|
| 2009 |
Xi ZX, Spiller K, Gardner EL. Mechanism-based medication development for the treatment of nicotine dependence. Acta Pharmacologica Sinica. 30: 723-39. PMID 19434058 DOI: 10.1038/Aps.2009.46 |
0.648 |
|
| 2009 |
Spiller K, Xi ZX, Li X, Ashby CR, Callahan PM, Tehim A, Gardner EL. Varenicline attenuates nicotine-enhanced brain-stimulation reward by activation of alpha4beta2 nicotinic receptors in rats. Neuropharmacology. 57: 60-6. PMID 19393252 DOI: 10.1016/J.Neuropharm.2009.04.006 |
0.658 |
|
| 2009 |
Xi ZX, Kleitz HK, Deng X, Ladenheim B, Peng XQ, Li X, Gardner EL, Stein EA, Cadet JL. A single high dose of methamphetamine increases cocaine self-administration by depletion of striatal dopamine in rats. Neuroscience. 161: 392-402. PMID 19336247 DOI: 10.1016/J.Neuroscience.2009.03.060 |
0.597 |
|
| 2009 |
Li X, Li J, Peng XQ, Spiller K, Gardner EL, Xi ZX. Metabotropic glutamate receptor 7 modulates the rewarding effects of cocaine in rats: involvement of a ventral pallidal GABAergic mechanism. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 1783-96. PMID 19158667 DOI: 10.1038/Npp.2008.236 |
0.787 |
|
| 2009 |
Peng XQ, Ashby CR, Spiller K, Li X, Li J, Thomasson N, Millan MJ, Mocaër E, Muńoz C, Gardner EL, Xi ZX. The preferential dopamine D3 receptor antagonist S33138 inhibits cocaine reward and cocaine-triggered relapse to drug-seeking behavior in rats. Neuropharmacology. 56: 752-60. PMID 19136017 DOI: 10.1016/J.Neuropharm.2008.12.007 |
0.778 |
|
| 2009 |
Li X, Hoffman AF, Peng XQ, Lupica CR, Gardner EL, Xi ZX. Attenuation of basal and cocaine-enhanced locomotion and nucleus accumbens dopamine in cannabinoid CB1-receptor-knockout mice. Psychopharmacology. 204: 1-11. PMID 19099297 DOI: 10.1007/S00213-008-1432-0 |
0.572 |
|
| 2008 |
Xi ZX, Gardner EL. Hypothesis-driven medication discovery for the treatment of psychostimulant addiction. Current Drug Abuse Reviews. 1: 303-27. PMID 19430578 DOI: 10.2174/1874473710801030303 |
0.303 |
|
| 2008 |
Thanos PK, Michaelides M, Ho CW, Wang GJ, Newman AH, Heidbreder CA, Ashby CR, Gardner EL, Volkow ND. The effects of two highly selective dopamine D3 receptor antagonists (SB-277011A and NGB-2904) on food self-administration in a rodent model of obesity. Pharmacology, Biochemistry, and Behavior. 89: 499-507. PMID 18329700 DOI: 10.1016/J.Pbb.2008.02.003 |
0.406 |
|
| 2008 |
Li X, Gardner EL, Xi ZX. The metabotropic glutamate receptor 7 (mGluR7) allosteric agonist AMN082 modulates nucleus accumbens GABA and glutamate, but not dopamine, in rats. Neuropharmacology. 54: 542-51. PMID 18155073 DOI: 10.1016/J.Neuropharm.2007.11.005 |
0.334 |
|
| 2008 |
Peng XQ, Li X, Li J, Ramachandran PV, Gagare PD, Pratihar D, Ashby CR, Gardner EL, Xi ZX. Effects of gabapentin on cocaine self-administration, cocaine-triggered relapse and cocaine-enhanced nucleus accumbens dopamine in rats. Drug and Alcohol Dependence. 97: 207-15. PMID 18065162 DOI: 10.1016/J.Drugalcdep.2007.09.019 |
0.607 |
|
| 2008 |
Peng XQ, Li X, Gilbert JG, Pak AC, Ashby CR, Brodie JD, Dewey SL, Gardner EL, Xi ZX. Gamma-vinyl GABA inhibits cocaine-triggered reinstatement of drug-seeking behavior in rats by a non-dopaminergic mechanism. Drug and Alcohol Dependence. 97: 216-25. PMID 18063319 DOI: 10.1016/J.Drugalcdep.2007.10.004 |
0.599 |
|
| 2008 |
Spiller K, Xi ZX, Peng XQ, Newman AH, Ashby CR, Heidbreder C, Gaál J, Gardner EL. The selective dopamine D3 receptor antagonists SB-277011A and NGB 2904 and the putative partial D3 receptor agonist BP-897 attenuate methamphetamine-enhanced brain stimulation reward in rats. Psychopharmacology. 196: 533-42. PMID 17985117 DOI: 10.1007/S00213-007-0986-6 |
0.726 |
|
| 2008 |
Xi ZX, Spiller K, Pak AC, Gilbert J, Dillon C, Li X, Peng XQ, Gardner EL. Cannabinoid CB1 receptor antagonists attenuate cocaine's rewarding effects: experiments with self-administration and brain-stimulation reward in rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 1735-45. PMID 17728698 DOI: 10.1038/Sj.Npp.1301552 |
0.776 |
|
| 2007 |
Xi ZX, Yang Z, Li SJ, Li X, Dillon C, Peng XQ, Spiller K, Gardner EL. Levo-tetrahydropalmatine inhibits cocaine's rewarding effects: experiments with self-administration and brain-stimulation reward in rats. Neuropharmacology. 53: 771-82. PMID 17888459 DOI: 10.1016/J.Neuropharm.2007.08.004 |
0.773 |
|
| 2007 |
Xi ZX, Gardner EL. Pharmacological actions of NGB 2904, a selective dopamine D3 receptor antagonist, in animal models of drug addiction. Cns Drug Reviews. 13: 240-59. PMID 17627675 DOI: 10.1111/J.1527-3458.2007.00013.X |
0.636 |
|
| 2007 |
Heidbreder CA, Andreoli M, Marcon C, Hutcheson DM, Gardner EL, Ashby CR. Evidence for the role of dopamine D3 receptors in oral operant alcohol self-administration and reinstatement of alcohol-seeking behavior in mice. Addiction Biology. 12: 35-50. PMID 17407496 DOI: 10.1111/J.1369-1600.2007.00051.X |
0.377 |
|
| 2006 |
Pak AC, Ashby CR, Heidbreder CA, Pilla M, Gilbert J, Xi ZX, Gardner EL. The selective dopamine D3 receptor antagonist SB-277011A reduces nicotine-enhanced brain reward and nicotine-paired environmental cue functions. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 9: 585-602. PMID 16942635 DOI: 10.1017/S1461145706006560 |
0.491 |
|
| 2006 |
Xi ZX, Gilbert JG, Peng XQ, Pak AC, Li X, Gardner EL. Cannabinoid CB1 receptor antagonist AM251 inhibits cocaine-primed relapse in rats: role of glutamate in the nucleus accumbens. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 8531-6. PMID 16914679 DOI: 10.1523/Jneurosci.0726-06.2006 |
0.596 |
|
| 2006 |
Gardner EL, Liu X, Paredes W, Giordano A, Spector J, Lepore M, Wu KM, Froimowitz M. A slow-onset, long-duration indanamine monoamine reuptake inhibitor as a potential maintenance pharmacotherapy for psychostimulant abuse: effects in laboratory rat models relating to addiction. Neuropharmacology. 51: 993-1003. PMID 16901516 DOI: 10.1016/J.Neuropharm.2006.06.009 |
0.583 |
|
| 2006 |
Xi ZX, Newman AH, Gilbert JG, Pak AC, Peng XQ, Ashby CR, Gitajn L, Gardner EL. The novel dopamine D3 receptor antagonist NGB 2904 inhibits cocaine's rewarding effects and cocaine-induced reinstatement of drug-seeking behavior in rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 1393-405. PMID 16205781 DOI: 10.1038/Sj.Npp.1300912 |
0.648 |
|
| 2005 |
Xi ZX, Gilbert JG, Pak AC, Ashby CR, Heidbreder CA, Gardner EL. Selective dopamine D3 receptor antagonism by SB-277011A attenuates cocaine reinforcement as assessed by progressive-ratio and variable-cost-variable-payoff fixed-ratio cocaine self-administration in rats. The European Journal of Neuroscience. 21: 3427-38. PMID 16026480 DOI: 10.1111/J.1460-9568.2005.04159.X |
0.599 |
|
| 2005 |
Heidbreder CA, Gardner EL, Xi ZX, Thanos PK, Mugnaini M, Hagan JJ, Ashby CR. The role of central dopamine D3 receptors in drug addiction: a review of pharmacological evidence. Brain Research. Brain Research Reviews. 49: 77-105. PMID 15960988 DOI: 10.1016/J.Brainresrev.2004.12.033 |
0.394 |
|
| 2005 |
Gardner EL. Endocannabinoid signaling system and brain reward: emphasis on dopamine. Pharmacology, Biochemistry, and Behavior. 81: 263-84. PMID 15936806 DOI: 10.1016/J.Pbb.2005.01.032 |
0.517 |
|
| 2005 |
Thanos PK, Katana JM, Ashby CR, Michaelides M, Gardner EL, Heidbreder CA, Volkow ND. The selective dopamine D3 receptor antagonist SB-277011-A attenuates ethanol consumption in ethanol preferring (P) and non-preferring (NP) rats. Pharmacology, Biochemistry, and Behavior. 81: 190-7. PMID 15894078 DOI: 10.1016/J.Pbb.2005.03.013 |
0.428 |
|
| 2005 |
Gilbert JG, Newman AH, Gardner EL, Ashby CR, Heidbreder CA, Pak AC, Peng XQ, Xi ZX. Acute administration of SB-277011A, NGB 2904, or BP 897 inhibits cocaine cue-induced reinstatement of drug-seeking behavior in rats: role of dopamine D3 receptors. Synapse (New York, N.Y.). 57: 17-28. PMID 15858839 DOI: 10.1002/Syn.20152 |
0.607 |
|
| 2004 |
Hayes RJ, Gardner EL. The basolateral complex of the amygdala mediates the modulation of intracranial self-stimulation threshold by drug-associated cues. The European Journal of Neuroscience. 20: 273-80. PMID 15245499 DOI: 10.1111/J.1460-9568.2004.03463.X |
0.507 |
|
| 2004 |
Gorelick DA, Gardner EL, Xi ZX. Agents in development for the management of cocaine abuse. Drugs. 64: 1547-73. PMID 15233592 DOI: 10.2165/00003495-200464140-00004 |
0.598 |
|
| 2004 |
Luo F, Xi ZX, Wu G, Liu C, Gardner EL, Li SJ. Attenuation of brain response to heroin correlates with the reinstatement of heroin-seeking in rats by fMRI. Neuroimage. 22: 1328-35. PMID 15219605 DOI: 10.1016/J.Neuroimage.2004.03.017 |
0.417 |
|
| 2004 |
Heidbreder CA, Andreoli M, Marcon C, Thanos PK, Ashby CR, Gardner EL. Role of dopamine D3 receptors in the addictive properties of ethanol. Drugs of Today (Barcelona, Spain : 1998). 40: 355-65. PMID 15190388 DOI: 10.1358/Dot.2004.40.4.820081 |
0.401 |
|
| 2004 |
Xi ZX, Gilbert J, Campos AC, Kline N, Ashby CR, Hagan JJ, Heidbreder CA, Gardner EL. Blockade of mesolimbic dopamine D3 receptors inhibits stress-induced reinstatement of cocaine-seeking in rats. Psychopharmacology. 176: 57-65. PMID 15083257 DOI: 10.1007/S00213-004-1858-Y |
0.593 |
|
| 2003 |
Ashby CR, Paul M, Gardner EL, Heidbreder CA, Hagan JJ. Acute administration of the selective D3 receptor antagonist SB-277011A blocks the acquisition and expression of the conditioned place preference response to heroin in male rats. Synapse (New York, N.Y.). 48: 154-6. PMID 12645041 DOI: 10.1002/Syn.10188 |
0.325 |
|
| 2003 |
Hayes RJ, Vorel SR, Spector J, Liu X, Gardner EL. Electrical and chemical stimulation of the basolateral complex of the amygdala reinstates cocaine-seeking behavior in the rat. Psychopharmacology. 168: 75-83. PMID 12545331 DOI: 10.1007/S00213-002-1328-3 |
0.817 |
|
| 2003 |
Sharan N, Chong VZ, Nair VD, Mishra RK, Hayes RJ, Gardner EL. Cocaine treatment increases expression of a 40 kDa catecholamine-regulated protein in discrete brain regions. Synapse (New York, N.Y.). 47: 33-44. PMID 12422371 DOI: 10.1002/Syn.10140 |
0.549 |
|
| 2002 |
Gardner EL. Addictive potential of cannabinoids: the underlying neurobiology. Chemistry and Physics of Lipids. 121: 267-90. PMID 12505706 DOI: 10.1016/S0009-3084(02)00162-7 |
0.513 |
|
| 2002 |
Vorel SR, Ashby CR, Paul M, Liu X, Hayes R, Hagan JJ, Middlemiss DN, Stemp G, Gardner EL. Dopamine D3 receptor antagonism inhibits cocaine-seeking and cocaine-enhanced brain reward in rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 9595-603. PMID 12417684 DOI: 10.1523/Jneurosci.22-21-09595.2002 |
0.837 |
|
| 2002 |
Gardner EL, Schiffer WK, Horan BA, Highfield D, Dewey SL, Brodie JD, Ashby CR. Gamma-vinyl GABA, an irreversible inhibitor of GABA transaminase, alters the acquisition and expression of cocaine-induced sensitization in male rats. Synapse (New York, N.Y.). 46: 240-50. PMID 12373739 DOI: 10.1002/Syn.10138 |
0.563 |
|
| 2002 |
Ashby CR, Paul M, Gardner EL, Gerasimov MR, Dewey SL, Lennon IC, Taylor SJ. Systemic administration of 1R,4S-4-amino-cyclopent-2-ene-carboxylic acid, a reversible inhibitor of GABA transaminase, blocks expression of conditioned place preference to cocaine and nicotine in rats. Synapse (New York, N.Y.). 44: 61-3. PMID 11891877 DOI: 10.1002/Syn.10052 |
0.523 |
|
| 2001 |
Horan B, Gardner EL, Dewey SL, Brodie JD, Ashby CR. The selective σ1 receptor agonist, 1-(3,4-dimethoxyphenethyl)-4-(phenylpropyl)piperazine (SA4503), blocks the acquisition of the conditioned place preference response to (-)-nicotine in rats European Journal of Pharmacology. 426. PMID 11525784 DOI: 10.1016/S0014-2999(01)01229-8 |
0.369 |
|
| 2001 |
Paul M, Dewey SL, Gardner EL, Brodie JD, Ashby CR. Gamma-vinyl GABA (GVG) blocks expression of the conditioned place preference response to heroin in rats Synapse. 41: 219-220. PMID 11391783 DOI: 10.1002/Syn.1078 |
0.357 |
|
| 2001 |
Vorel SR, Liu X, Hayes RJ, Spector JA, Gardner EL. Relapse to cocaine-seeking after hippocampal theta burst stimulation. Science (New York, N.Y.). 292: 1175-8. PMID 11349151 DOI: 10.1126/Science.1058043 |
0.821 |
|
| 2001 |
Gerasimov MR, Schiffer WK, Gardner EL, Marsteller DA, Lennon IC, Taylor SJ, Brodie JD, Ashby CR, Dewey SL. GABAergic blockade of cocaine-associated cue-induced increases in nucleus accumbens dopamine. European Journal of Pharmacology. 414: 205-9. PMID 11239920 DOI: 10.1016/S0014-2999(01)00800-7 |
0.592 |
|
| 2000 |
Gardner EL. What we have learned about addiction from animal models of drug self-administration American Journal On Addictions. 9: 285-313. PMID 11155784 DOI: 10.1080/105504900750047355 |
0.434 |
|
| 2000 |
Froimowitz M, Wu KM, Moussa A, Haidar RM, Jurayj J, George C, Gardner EL. Slow-onset, long-duration 3-(3′,4′-dichlorophenyl)-1-indanamine monoamine reuptake blockers as potential medications to treat cocaine abuse Journal of Medicinal Chemistry. 43: 4981-4992. PMID 11150168 DOI: 10.1021/Jm000201D |
0.412 |
|
| 2000 |
Gardner EL, Ashby CR. Heterogeneity of the mesotelencephalic dopamine fibers: Physiology and pharmacology Neuroscience and Biobehavioral Reviews. 24: 115-118. PMID 10654666 DOI: 10.1016/S0149-7634(99)00048-2 |
0.378 |
|
| 2000 |
Horan B, Gardner EL, Ashby CR. Enhancement of conditioned place preference response to cocaine in rats following subchronic administration of 3,4-methylenedioxymethamphetamine (MDMA) Synapse. 35: 160-162. PMID 10611642 DOI: 10.1002/(Sici)1098-2396(200002)35:2<160::Aid-Syn9>3.0.Co;2-O |
0.572 |
|
| 1999 |
Gerasimov MR, Ashby CR, Gardner EL, Mills MJ, Brodie JD, Dewey SL. Gamma-vinyl GABA inhibits methamphetamine, heroin, or ethanol-induced increases in nucleus accumbens dopamine. Synapse (New York, N.Y.). 34: 11-9. PMID 10459167 DOI: 10.1002/(Sici)1098-2396(199910)34:1<11::Aid-Syn2>3.0.Co;2-5 |
0.476 |
|
| 1999 |
Dewey SL, Brodie JD, Gerasimov M, Horan B, Gardner EL, Ashby CR. A pharmacologic strategy for the treatment of nicotine addiction Synapse. 31: 76-86. PMID 10025686 DOI: 10.1002/(Sici)1098-2396(199901)31:1<76::Aid-Syn10>3.0.Co;2-Y |
0.404 |
|
| 1998 |
Gardner EL, Vorel SR. Cannabinoid transmission and reward-related events. Neurobiology of Disease. 5: 502-33. PMID 9974181 DOI: 10.1006/Nbdi.1998.0219 |
0.799 |
|
| 1998 |
Dewey SL, Morgan AE, Ashby CR, Horan B, Kushner SA, Logan J, Volkow ND, Fowler JS, Gardner EL, Brodie JD. A novel strategy for the treatment of cocaine addiction. Synapse (New York, N.Y.). 30: 119-29. PMID 9723781 DOI: 10.1002/(Sici)1098-2396(199810)30:2<119::Aid-Syn1>3.0.Co;2-F |
0.559 |
|
| 1998 |
Minabe Y, Gardner EL, Ashby CR. Differential effects of chronic haloperidol administration on midbrain dopamine neurons in Sprague-Dawley, fischer 344, and lewis rats: An in vivo electrophysiological study Synapse. 29: 269-271. PMID 9635897 DOI: 10.1002/(Sici)1098-2396(199807)29:3<269::Aid-Syn9>3.0.Co;2-4 |
0.396 |
|
| 1997 |
Gifford AN, Gardner EL, Ashby CR. The effect of intravenous administration of delta-9-tetrahydrocannabinol on the activity of A10 dopamine neurons recorded in vivo in anesthetized rats Neuropsychobiology. 36: 96-99. PMID 9267859 DOI: 10.1159/000119369 |
0.382 |
|
| 1997 |
Horan B, Smith M, Gardner EL, Lepore M, Ashby CR. (-)-Nicotine produces conditioned place preference in Lewis, but not Fischer 344 rats Synapse. 26: 93-94. PMID 9097409 DOI: 10.1002/(Sici)1098-2396(199705)26:1<93::Aid-Syn10>3.0.Co;2-W |
0.315 |
|
| 1996 |
Lepore M, Liu X, Savage V, Matalon D, Gardner EL. Genetic differences in delta 9-tetrahydrocannabinol-induced facilitation of brain stimulation reward as measured by a rate-frequency curve-shift electrical brain stimulation paradigm in three different rat strains. Life Sciences. 58: PL365-72. PMID 8649214 DOI: 10.1016/0024-3205(96)00237-8 |
0.463 |
|
| 1996 |
Chen J, Marmur R, Paredes W, Pulles A, Gardner EL. Systemic cocaine challenge after chronic cocaine treatment reveals sensitization of extracellular dopamine levels in nucleus accumbens but direct cocaine perfusion into nucleus accumbens does not: Implications for the neural locus of cocaine sensitization Life Sciences. 58. PMID 8594313 DOI: 10.1016/S0024-3205(96)80014-2 |
0.583 |
|
| 1996 |
Chen J, Liu X, Paredes W, Gardner E. Acute fluoxetine enhances cocaine's action on brain reward Biological Psychiatry. 39: 537. DOI: 10.1016/0006-3223(96)84077-7 |
0.557 |
|
| 1995 |
Lepore M, Vorel SR, Lowinson J, Gardner EL. Conditioned place preference induced by delta 9-tetrahydrocannabinol: comparison with cocaine, morphine, and food reward. Life Sciences. 56: 2073-80. PMID 7776834 DOI: 10.1016/0024-3205(95)00191-8 |
0.81 |
|
| 1994 |
Gardner EL, Chen J, Paredes W. Clozapine produces potent antidopaminergic effects anatomically specific to the mesolimbic system Journal of Clinical Psychiatry. 55: 15-22. PMID 7961561 |
0.356 |
|
| 1993 |
Gardner EL, Chen J, Paredes W. Overview of chemical sampling techniques Journal of Neuroscience Methods. 48: 173-197. PMID 8412302 DOI: 10.1016/0165-0270(93)90091-5 |
0.308 |
|
| 1993 |
Chen J, Marmur R, Pulles A, Paredes W, Gardner EL. Ventral tegmental microinjection of Δ9-tetrahydrocannabinol enhances ventral tegmental somatodendritic dopamine levels but not forebrain dopamine levels: evidence for local neural action by marijuana's psychoactive ingredient Brain Research. 621: 65-70. PMID 8221074 DOI: 10.1016/0006-8993(93)90298-2 |
0.429 |
|
| 1993 |
Gardner EL, Walker LS, Paredes W. Clozapine's functional mesolimbic selectivity is not duplicated by the addition of anticholinergic action to haloperidol: a brain stimulation study in the rat Psychopharmacology. 110: 119-124. PMID 7870870 DOI: 10.1007/Bf02246960 |
0.43 |
|
| 1993 |
Gardner EL, Lowinson JH. Drug craving and positive/negative hedonic brain substrates activated by addicting drugs Seminars in Neuroscience. 5: 359-368. DOI: 10.1016/S1044-5765(05)80044-2 |
0.484 |
|
| 1993 |
Gardner EL. Introduction: The neurobiology of drug addiction/dependency Seminars in Neuroscience. 5: 313-314. DOI: 10.1016/S1044-5765(05)80037-5 |
0.341 |
|
| 1993 |
Gardner EL. Brain reward mechanisms and the neurobiology of craving Pharmacology Biochemistry and Behavior. 46: 496. DOI: 10.1016/0091-3057(93)90391-6 |
0.388 |
|
| 1992 |
Chen J, Ruan D, Paredes W, Gardner EL. Effects of acute and chronic clozapine on dopaminergic function in medial prefrontal cortex of awake, freely moving rats Brain Research. 571: 235-241. PMID 1611497 DOI: 10.1016/0006-8993(92)90660-2 |
0.403 |
|
| 1992 |
Chen J, Paredes W, Van Praag HM, Lowinson JH, Gardner EL. Presynaptic dopamine release is enhanced by 5-HT3 receptor activation in medial prefrontal cortex of freely moving rats. Synapse (New York, N.Y.). 10: 264-6. PMID 1557698 DOI: 10.1002/Syn.890100308 |
0.363 |
|
| 1992 |
Chen J, Paredes W, van Praag HM, Gardner EL. Serotonin denervation enhances responsiveness of presynaptic dopamine efflux to acute clozapine in nucleus accumbens but not in caudate-putamen. Brain Research. 582: 173-9. PMID 1379872 DOI: 10.1016/0006-8993(92)90335-7 |
0.386 |
|
| 1991 |
Chen J, Paredes W, Gardner EL. Chronic treatment with clozapine selectively decreases basal dopamine release in nucleus accumbens but not in caudate-putamen as measured by in vivo brain microdialysis: Further evidence for depolarization block Neuroscience Letters. 122: 127-131. PMID 2057129 DOI: 10.1016/0304-3940(91)90209-C |
0.414 |
|
| 1991 |
Gardner EL, Lowinson JH. Marijuana's interaction with brain reward systems: Update 1991 Pharmacology, Biochemistry and Behavior. 40: 571-580. PMID 1806947 DOI: 10.1016/0091-3057(91)90365-9 |
0.499 |
|
| 1991 |
Chen JP, van Praag HM, Gardner EL. Activation of 5-HT3 receptor by 1-phenylbiguanide increases dopamine release in the rat nucleus accumbens. Brain Research. 543: 354-7. PMID 1711914 DOI: 10.1016/0006-8993(91)90050-6 |
0.375 |
|
| 1991 |
Chen J, Paredes W, Lowinson JH, Gardner EL. Strain-specific facilitation of dopamine efflux by Δ9-tetrahydrocannabinol in the nucleus accumbens of rat: An in vivo microdialysis study Neuroscience Letters. 129: 136-140. PMID 1656336 DOI: 10.1016/0304-3940(91)90739-G |
0.455 |
|
| 1990 |
Chen J, Paredes W, Li J, Smith D, Lowinson J, Gardner EL. Δ9-Tetrahydrocannabinol produces naloxone-blockable enhancement of presynaptic basal dopamine efflux in nucleus accumbens of conscious, freely-moving rats as measured by intracerebral microdialysis Psychopharmacology. 102: 156-162. PMID 2177204 DOI: 10.1007/Bf02245916 |
0.518 |
|
| 1990 |
Jianping C, Paredes W, Lowinson JH, Gardner EL. Δ9-Tetrahydroeannabinol enhances presynaptic dopamine efflux In medial prefrontal cortex European Journal of Pharmacology. 190: 259-262. PMID 1963849 DOI: 10.1016/0014-2999(90)94136-L |
0.434 |
|
| 1990 |
Gardner EL, Chen J, Paredes W, Smith D, Li J, Lowinson J. Enhancement of presynaptic dopamine efflux in brain by Δ9-tetrahydro-cannabinol is mediated by an endogenous opioid mechanism New Leads in Opioid Research: Proceedings of the International Narcotics Research Conference. Ics914. 243. |
0.374 |
|
| 1988 |
Lindenmayer JP, Gardner E, Goldberg E, Opler LA, Kay SR, van Praag HM, Weiner M, Zukin S. High-dose naloxone in tardive dyskinesia. Psychiatry Research. 26: 19-28. PMID 3070611 DOI: 10.1016/0165-1781(88)90083-2 |
0.324 |
|
| 1988 |
Ng Cheong Ton JM, Gerhardt GA, Friedemann M, Etgen AM, Rose GM, Sharpless NS, Gardner EL. The effects of delta 9-tetrahydrocannabinol on potassium-evoked release of dopamine in the rat caudate nucleus: an in vivo electrochemical and in vivo microdialysis study. Brain Research. 451: 59-68. PMID 2855215 DOI: 10.1016/0006-8993(88)90749-4 |
0.457 |
|
| 1988 |
Gardner EL, Paredes W, Smith D, Donner A, Milling C, Cohen D, Morrison D. Facilitation of brain stimulation reward by Δ 9-tetrahydrocannabinol Psychopharmacology. 96: 142-144. PMID 2852376 DOI: 10.1007/Bf02431546 |
0.458 |
|
| 1988 |
Gardner EL, Seeger TF. Anatomically selective action of atypical neuroleptics on the mesocorticolimbic dopamine system Annals of the New York Academy of Sciences. 537: 502-504. DOI: 10.1111/J.1749-6632.1988.Tb42140.X |
0.389 |
|
| 1986 |
Zukin SR, Tempel A, Gardner EL, Zukin RS. Interaction of [3H](-)-SKF-10,047 with brain sigma receptors: characterization and autoradiographic visualization. Journal of Neurochemistry. 46: 1032-41. PMID 3005501 DOI: 10.1111/J.1471-4159.1986.Tb00614.X |
0.36 |
|
| 1984 |
Broderick PA, Gardner EL, Van Praag HM. In vivo electrochemical and behavioral evidence for specific neural substrates modulated differentially by enkephalin in rat stimulant stereotypy and locomotion Biological Psychiatry. 19: 45-54. PMID 6538442 |
0.363 |
|
| 1984 |
Tempel A, Gardner EL, Zukin RS. Visualization of opiate receptor upregulation by light microscopy autoradiography. Proceedings of the National Academy of Sciences of the United States of America. 81: 3893-7. PMID 6328530 |
0.305 |
|
| 1983 |
Broderick PA, Gardner EL, van Praag HM. Similar effects of an enkephalin analog on mesolimbic dopamine release and hyperactivity in rats Life Sciences. 33: 635-638. PMID 6686641 DOI: 10.1016/0024-3205(83)90583-0 |
0.434 |
|
| 1983 |
Gardner EL, Seeger TF. Neurobehavioral evidence for mesolimbic specificity of action by clozapine: Studies using electrical intracranial self-stimulation Biological Psychiatry. 18: 1357-1362. PMID 6661466 |
0.303 |
|
| 1983 |
Hirschhorn ID, Hittner D, Gardner EL, Cubells J, Makman MH. Evidence for a role of endogenous opioids in the nigrostriatal system: Influence of naloxone and morphine on nigrostriatal dopaminergic supersensitivity Brain Research. 270: 109-117. PMID 6409355 DOI: 10.1016/0006-8993(83)90796-5 |
0.307 |
|
| 1982 |
Marotta RF, Logan N, Riverso S, Gardner EL. Mitigation of the septal lesion syndrome by pre-lesion chronic treatment with haloperidol Pharmacology, Biochemistry and Behavior. 16: 769-775. PMID 7089035 DOI: 10.1016/0091-3057(82)90233-7 |
0.316 |
|
| 1982 |
Seeger TF, Thal L, Gardner EL. Behavioral and biochemical aspects of neuroleptic-induced dopaminergic supersensitivity: Studies with chronic clozapine and haloperidol Psychopharmacology. 76: 182-187. PMID 6805029 DOI: 10.1007/Bf00435275 |
0.427 |
|
| 1982 |
Tempel A, Zukin RS, Gardner EL. Supersensitivity of brain opiate receptor subtypes after chronic naltrexone treatment. Life Sciences. 31: 1401-4. PMID 6292636 DOI: 10.1016/0024-3205(82)90391-5 |
0.362 |
|
| 1981 |
Nazzaro JM, Seeger TF, Gardner EL. Morphine differentially affects ventral tegmental and substantia nigra brain reward thresholds Pharmacology, Biochemistry and Behavior. 14: 325-331. PMID 7232458 DOI: 10.1016/0091-3057(81)90398-1 |
0.452 |
|
| 1981 |
Seeger TF, Gardner EL, Bridger WF. Increase in mesolimbic electrical self-stimulation after chronic haloperidol: reversal by L-DOPA or lithium Brain Research. 215: 404-409. PMID 6790126 DOI: 10.1016/0006-8993(81)90525-4 |
0.394 |
|
| 1981 |
Walczak SA, Makman MH, Gardner EL. Acetylmethadol metabolites influence opiate receptors and adenylate cyclase in amygdala European Journal of Pharmacology. 72: 343-349. PMID 6268422 DOI: 10.1016/0014-2999(81)90573-2 |
0.401 |
|
| 1981 |
Bridger W, Gardner E, Barr G, Seeger T. Drug induced supersensitivity as measured by electrical self-stimulation and conditioned avoidance behavior Journal of Psychiatric Research. 16: 129-130. DOI: 10.1016/0022-3956(81)90029-7 |
0.354 |
|
| 1980 |
Seeger TF, Nazzaro JM, Gardner EL. Selective inhibition of mesolimbic behavioral supersensitivity by naloxone European Journal of Pharmacology. 65: 435-438. PMID 7408948 DOI: 10.1016/0014-2999(80)90350-7 |
0.388 |
|
| 1980 |
Gardner EL, Zukin RS, Makman MH. Modulation of opiate receptor binding in striatum and amygdala by selective mesencephalic lesions. Brain Research. 194: 232-9. PMID 6247033 DOI: 10.1016/0006-8993(80)91335-9 |
0.304 |
|
| 1979 |
Thal L, Mishra RK, Gardner EL, Horowitz SG, Varmuza S, Makman MH. Dopamine antagonist binding increases in two behaviorally distinct striatal denervation syndromes Brain Research. 170: 381-386. PMID 572733 DOI: 10.1016/0006-8993(79)90119-7 |
0.376 |
|
| 1979 |
Rosenfeld MR, Seeger TF, Sharpless NS, Gardner EL, Makman MH. Denervation supersensitivity in the mesolimbic system: involvement of dopamine-stimulated adenylate cyclase Brain Research. 173: 572-576. PMID 487111 DOI: 10.1016/0006-8993(79)90255-5 |
0.424 |
|
| 1979 |
Seeger TF, Gardner EL. Enhancement of self-stimulation behavior in rats and monkeys after chronic neuroleptic treatment: Evidence for mesolimbic supersensitivity Brain Research. 175: 49-57. PMID 114275 DOI: 10.1016/0006-8993(79)90513-4 |
0.459 |
|
| 1979 |
Ahn HS, Gardner E, Makman MH. Anterior pituitary adenylate cyclase: stimulation by dopamine and other monoamines. European Journal of Pharmacology. 53: 313-7. PMID 103734 DOI: 10.1016/0014-2999(79)90139-0 |
0.438 |
|
| 1977 |
Marotta RF, Logan N, Potegal M, Glusman M, Gardner EL. Dopamine agonists induce recovery from surgically-induced septal rage Nature. 269: 513-515. PMID 909599 DOI: 10.1038/269513A0 |
0.385 |
|
| 1976 |
Gardner EL, Mishra RK, Iordanidis P. Catalytic and receptor components of enhanced dopamine stimulated adenylate cyclase in 2 behaviorally distinct striatal denervation syndromes Federation Proceedings. 35. |
0.303 |
|
| 1974 |
Mishra RK, Gardner EL, Katzman R, Makman MH. Enhancement of dopamine-stimulated adenylate cyclase activity in rat caudate after lesions in substantia nigra: evidence for denervation supersensitivity. Proceedings of the National Academy of Sciences of the United States of America. 71: 3883-7. PMID 4372596 DOI: 10.1073/Pnas.71.10.3883 |
0.406 |
|
| 1974 |
Jackson WJ, Gardner EL. Modulation of hypothalamic ICSS by concurrent limbic stimulation Physiology and Behavior. 12: 177-182. PMID 4205808 DOI: 10.1016/0031-9384(74)90170-X |
0.337 |
|
| 1971 |
Routtenberg A, Gardner EL, Huang YH. Self-stimulation pathways in the monkey, Macaca mulatta. Experimental Neurology. 33: 213-24. PMID 4107565 DOI: 10.1016/0014-4886(71)90115-4 |
0.36 |
|
| 1971 |
Gardner EL. An improved technique for determining brain reward thresholds in primates Behavior Research Methods &Amp; Instrumentation. 3: 273-274. DOI: 10.3758/Bf03208404 |
0.345 |
|
| Show low-probability matches. |