Patrick M. Beardsley, Ph.D. - Publications

Affiliations: 
Pharmacology and Toxicology Virginia Commonwealth University, Richmond, VA, United States 
Area:
drug abuse, behavioral pharmacology, rat/primate self administration

56 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Zheng Y, Obeng S, Reinecke BA, Chen C, Phansalkar PS, Walentiny DM, Gerk PM, Liu-Chen LY, Selley DE, Beardsley PM, Zhang Y. Pharmacological characterization of 17-cyclopropylmethyl-3,14-dihydroxy-4,5-epoxy-6-[(3'-fluoro-4'-pyridyl)acetamido]morphinan (NFP) as a dual selective MOR/KOR ligand with potential applications in treating opioid use disorder. European Journal of Pharmacology. 172812. PMID 31743739 DOI: 10.1016/J.Ejphar.2019.172812  0.303
2019 Younis RM, Taylor RM, Beardsley PM, McClay JL. The gene and its associated phenotypes: focus on CNS drug response. Pharmacogenomics. 20: 669-684. PMID 31250731 DOI: 10.2217/Pgs-2019-0015  0.312
2019 Varshneya NB, Walentiny DM, Moisa LT, Walker TD, Akinfiresoye LR, Beardsley PM. Opioid-like antinociceptive and locomotor effects of emerging fentanyl-related substances. Neuropharmacology. PMID 30904478 DOI: 10.1016/J.Neuropharm.2019.03.023  0.342
2019 Walentiny DM, Moisa LT, Beardsley PM. Oxycodone-Like Discriminative Stimulus Effects of Fentanyl-Related Emerging Drugs of Abuse in Mice. Neuropharmacology. PMID 30735691 DOI: 10.1016/J.Neuropharm.2019.02.007  0.363
2018 Walentiny DM, Wiebelhaus JM, Beardsley PM. Nociceptin/orphanin FQ receptors modulate the discriminative stimulus effects of oxycodone in C57BL/6 mice. Drug and Alcohol Dependence. 187: 335-342. PMID 29705547 DOI: 10.1016/J.Drugalcdep.2018.02.035  0.355
2017 Bachtell RK, Jones JD, Heinzerling KG, Beardsley PM, Comer SD. Glial and neuroinflammatory targets for treating substance use disorders. Drug and Alcohol Dependence. 180: 156-170. PMID 28892721 DOI: 10.1016/J.Drugalcdep.2017.08.003  0.339
2017 Enga RM, Rice AC, Weller P, Subler MA, Lee D, Hall CP, Windle JJ, Beardsley PM, van den Oord EJ, McClay JL. Initial characterization of behavior and ketamine response in a mouse knockout of the post-synaptic effector gene Anks1b. Neuroscience Letters. PMID 28115237 DOI: 10.1016/J.Neulet.2017.01.044  0.368
2016 Enga RM, Jackson A, Damaj MI, Beardsley PM. Oxycodone physical dependence and its oral self-administration in C57BL/6J mice. European Journal of Pharmacology. PMID 27393461 DOI: 10.1016/J.Ejphar.2016.07.006  0.373
2016 Poland RS, Hahn Y, Knapp PE, Beardsley PM, Bowers MS. Ibudilast attenuates expression of behavioral sensitization to cocaine in male and female rats. Neuropharmacology. PMID 27343385 DOI: 10.1016/J.Neuropharm.2016.06.024  0.397
2016 Owens RA, Ignatowska-Jankowska BM, Mustafa M, Beardsley PM, Wiley JL, Jali A, Selley DE, Niphakis M, Cravatt BF, Lichtman AH. Discriminative Stimulus Properties of the Endocannabinoid Catabolic Enzyme Inhibitor SA-57 in Mice. The Journal of Pharmacology and Experimental Therapeutics. PMID 27307500 DOI: 10.1124/Jpet.115.229492  0.373
2015 Wiebelhaus JM, Walentiny DM, Beardsley PM. Effects of acute and repeated administration of oxycodone and naloxone-precipitated withdrawal on Intracranial Self-Stimulation (ICSS) in rats. The Journal of Pharmacology and Experimental Therapeutics. PMID 26491062 DOI: 10.1124/Jpet.115.228940  0.391
2015 Vengeliene V, Moeller A, Meinhardt MW, Beardsley PM, Sommer WH, Spanagel R, Bespalov A. The Calpain Inhibitor A-705253 Attenuates Alcohol-Seeking and Relapse with Low Side-Effect Profile. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 26216521 DOI: 10.1038/Npp.2015.225  0.317
2015 McClay JL, Vunck SA, Batman AM, Crowley JJ, Vann RE, Beardsley PM, van den Oord EJ. Neurochemical Metabolomics Reveals Disruption to Sphingolipid Metabolism Following Chronic Haloperidol Administration. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. PMID 25850894 DOI: 10.1007/S11481-015-9605-1  0.74
2015 Vengeliene V, Moeller A, Meinhardt MW, Beardsley P, Sommer WH, Spanagel R, Bespalov A. Sy09-2The Calpain Inhibitor A-705253 Attenuates Alcohol-Seeking And Relapse With Low Side-Effect Profile Alcohol and Alcoholism. 50. DOI: 10.1093/Alcalc/Agv076.35  0.305
2014 Wiley JL, Walentiny DM, Wright MJ, Beardsley PM, Burston JJ, Poklis JL, Lichtman AH, Vann RE. Endocannabinoid contribution to Δ9-tetrahydrocannabinol discrimination in rodents. European Journal of Pharmacology. 737: 97-105. PMID 24858366 DOI: 10.1016/J.Ejphar.2014.05.013  0.694
2014 El-Hage N, Rodriguez M, Podhaizer EM, Zou S, Dever SM, Snider SE, Knapp PE, Beardsley PM, Hauser KF. Ibudilast (AV411), and its AV1013 analog, reduce HIV-1 replication and neuronal death induced by HIV-1 and morphine. Aids (London, England). 28: 1409-19. PMID 24732776 DOI: 10.1097/Qad.0000000000000291  0.659
2014 Beardsley PM, Hauser KF. Glial modulators as potential treatments of psychostimulant abuse. Advances in Pharmacology (San Diego, Calif.). 69: 1-69. PMID 24484974 DOI: 10.1016/B978-0-12-420118-7.00001-9  0.34
2013 Adkins DE, McClay JL, Vunck SA, Batman AM, Vann RE, Clark SL, Souza RP, Crowley JJ, Sullivan PF, van den Oord EJ, Beardsley PM. Behavioral metabolomics analysis identifies novel neurochemical signatures in methamphetamine sensitization. Genes, Brain, and Behavior. 12: 780-91. PMID 24034544 DOI: 10.1111/Gbb.12081  0.732
2013 Aberg KA, Xie LY, McClay JL, Nerella S, Vunck S, Snider S, Beardsley PM, van den Oord EJ. Testing two models describing how methylome-wide studies in blood are informative for psychiatric conditions. Epigenomics. 5: 367-77. PMID 23895651 DOI: 10.2217/Epi.13.36  0.7
2013 McClay JL, Adkins DE, Vunck SA, Batman AM, Vann RE, Clark SL, Beardsley PM, van den Oord EJ. Large-scale neurochemical metabolomics analysis identifies multiple compounds associated with methamphetamine exposure. Metabolomics : Official Journal of the Metabolomic Society. 9: 392-402. PMID 23554582 DOI: 10.1007/S11306-012-0456-Y  0.741
2013 Uguen M, Perrin D, Belliard S, Ligneau X, Beardsley PM, Lecomte JM, Schwartz JC. Preclinical evaluation of the abuse potential of Pitolisant, a histamine H₃ receptor inverse agonist/antagonist compared with Modafinil. British Journal of Pharmacology. 169: 632-44. PMID 23472741 DOI: 10.1111/bph.12149  0.301
2013 Snider SE, Hendrick ES, Beardsley PM. Glial cell modulators attenuate methamphetamine self-administration in the rat. European Journal of Pharmacology. 701: 124-30. PMID 23375937 DOI: 10.1016/J.Ejphar.2013.01.016  0.736
2013 Shelton KL, Hendrick ES, Beardsley PM. Efficacy of buspirone for attenuating cocaine and methamphetamine reinstatement in rats. Drug and Alcohol Dependence. 129: 210-6. PMID 23374566 DOI: 10.1016/J.Drugalcdep.2013.01.003  0.337
2013 Webster K, Hillhouse T, Donahue T, Friar M, Joseph B, Beardsley P, Windle J, Stewart J, Porter J. A.10 - EFFECTS OF D-AMPHETAMINE IN VESICULAR MONOAMINE TRANSPORTER (VMAT)1 KNOCKOUT MICE SUGGEST A SCHIZOPHRENIC PHENOTYPE IN CONDITIONED AND UNCONDITIONED BEHAVIOR Behavioural Pharmacology. 24: e25. DOI: 10.1097/01.Fbp.0000434771.21238.50  0.581
2012 Beardsley PM, Shelton KL. Prime-, stress-, and cue-induced reinstatement of extinguished drug-reinforced responding in rats: cocaine as the prototypical drug of abuse. Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. Unit 9.39. PMID 23093352 DOI: 10.1002/0471142301.Ns0939S61  0.383
2012 Snider SE, Vunck SA, van den Oord EJ, Adkins DE, McClay JL, Beardsley PM. The glial cell modulators, ibudilast and its amino analog, AV1013, attenuate methamphetamine locomotor activity and its sensitization in mice. European Journal of Pharmacology. 679: 75-80. PMID 22306241 DOI: 10.1016/J.Ejphar.2012.01.013  0.742
2011 McClay JL, Adkins DE, Aberg K, Bukszár J, Khachane AN, Keefe RS, Perkins DO, McEvoy JP, Stroup TS, Vann RE, Beardsley PM, Lieberman JA, Sullivan PF, van den Oord EJ. Genome-wide pharmacogenomic study of neurocognition as an indicator of antipsychotic treatment response in schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 616-26. PMID 21107309 DOI: 10.1038/Npp.2010.193  0.639
2010 Batman AM, Dutta AK, Reith ME, Beardsley PM. The selective dopamine uptake inhibitor, D-84, suppresses cocaine self-administration, but does not occasion cocaine-like levels of generalization. European Journal of Pharmacology. 648: 127-32. PMID 20840845 DOI: 10.1016/J.Ejphar.2010.08.051  0.347
2010 Beardsley PM, Shelton KL, Hendrick E, Johnson KW. The glial cell modulator and phosphodiesterase inhibitor, AV411 (ibudilast), attenuates prime- and stress-induced methamphetamine relapse. European Journal of Pharmacology. 637: 102-8. PMID 20399770 DOI: 10.1016/J.Ejphar.2010.04.010  0.428
2010 Beardsley PM, Pollard GT, Howard JL, Carroll FI. Effectiveness of analogs of the kappa opioid receptor antagonist (3R)-7-hydroxy-N-((1S)-1-{[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl}-2-methylpropyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide (JDTic) to reduce U50,488-induced diuresis and stress-induced cocaine reinstatement in rats. Psychopharmacology. 210: 189-98. PMID 20372878 DOI: 10.1007/S00213-010-1846-3  0.398
2009 Kharkar PS, Batman AM, Zhen J, Beardsley PM, Reith ME, Dutta AK. Synthesis and biological characterization of (3R,4R)-4-(2-(benzhydryloxy)ethyl)-1-((R)-2-hydroxy-2-phenylethyl)-piperidin-3-ol and its stereoisomers for activity toward monoamine transporters. Chemmedchem. 4: 1075-85. PMID 19449323 DOI: 10.1002/Cmdc.200900085  0.352
2009 Beardsley PM, Thomas BF, McMahon LR. Cannabinoid CB1 receptor antagonists as potential pharmacotherapies for drug abuse disorders. International Review of Psychiatry (Abingdon, England). 21: 134-42. PMID 19367507 DOI: 10.1080/09540260902782786  0.36
2008 Shelton KL, Beardsley PM. Effect of drug-paired exteroceptive stimulus presentations on methamphetamine reinstatement in rats. Pharmacology, Biochemistry, and Behavior. 90: 434-40. PMID 18456312 DOI: 10.1016/J.Pbb.2008.03.028  0.358
2006 Vargas-Irwin C, van den Oord EJ, Beardsley PM, Robles JR. A method for analyzing strain differences in acquisition of IV cocaine self-administration in mice. Behavior Genetics. 36: 525-35. PMID 16586151 DOI: 10.1007/S10519-006-9068-5  0.308
2006 Newman JL, Beardsley PM. Effects of memantine, haloperidol, and cocaine on primary and conditioned reinforcement associated with cocaine in rhesus monkeys. Psychopharmacology. 185: 142-9. PMID 16425059 DOI: 10.1007/S00213-005-0282-2  0.609
2006 Vann RE, Balster RL, Beardsley PM. Dose, duration, and pattern of nicotine administration as determinants of behavioral dependence in rats. Psychopharmacology. 184: 482-93. PMID 16001123 DOI: 10.1007/S00213-005-0037-0  0.672
2005 Beardsley PM, Howard JL, Shelton KL, Carroll FI. Differential effects of the novel kappa opioid receptor antagonist, JDTic, on reinstatement of cocaine-seeking induced by footshock stressors vs cocaine primes and its antidepressant-like effects in rats. Psychopharmacology. 183: 118-26. PMID 16184376 DOI: 10.1007/S00213-005-0167-4  0.335
2005 Beardsley PM, Thomas BF. Current evidence supporting a role of cannabinoid CB1 receptor (CB1R) antagonists as potential pharmacotherapies for drug abuse disorders. Behavioural Pharmacology. 16: 275-96. PMID 16148435 DOI: 10.1097/00008877-200509000-00003  0.37
2005 Batman AM, Munzar P, Beardsley PM. Attenuation of nicotine's discriminative stimulus effects in rats and its locomotor activity effects in mice by serotonergic 5-HT2A/2C receptor agonists. Psychopharmacology. 179: 393-401. PMID 15565434 DOI: 10.1007/S00213-004-2035-Z  0.373
2004 Kolhatkar R, Cook CD, Ghorai SK, Deschamps J, Beardsley PM, Reith ME, Dutta AK. Further structurally constrained analogues of cis-(6-benzhydrylpiperidin-3-yl)benzylamine with elucidation of bioactive conformation: discovery of 1,4-diazabicyclo[3.3.1]nonane derivatives and evaluation of their biological properties for the monoamine transporters. Journal of Medicinal Chemistry. 47: 5101-13. PMID 15456254 DOI: 10.1021/Jm049796T  0.345
2004 Beardsley PM, Aceto MD, Cook CD, Bowman ER, Newman JL, Harris LS. Discriminative stimulus, reinforcing, physical dependence, and antinociceptive effects of oxycodone in mice, rats, and rhesus monkeys. Experimental and Clinical Psychopharmacology. 12: 163-72. PMID 15301633 DOI: 10.1037/1064-1297.12.3.163  0.571
2004 Cook CD, Newman JL, Winfree JC, Beardsley PM. Modulation of the locomotor activating effects of the noncompetitive NMDA receptor antagonist MK801 by dopamine D2/3 receptor agonists in mice. Pharmacology, Biochemistry, and Behavior. 77: 309-18. PMID 14751459 DOI: 10.1016/J.Pbb.2003.11.002  0.609
2003 Cook CD, Beardsley PM. The modulatory actions of dopamine D2/3 agonists and antagonists on the locomotor-activating effects of morphine and caffeine in mice. Pharmacology, Biochemistry, and Behavior. 75: 363-71. PMID 12873628 DOI: 10.1016/S0091-3057(03)00090-X  0.372
2003 Kozikowski AP, Johnson KM, Deschaux O, Bandyopadhyay BC, Araldi GL, Carmona G, Munzar P, Smith MP, Balster RL, Beardsley PM, Tella SR. Mixed cocaine agonist/antagonist properties of (+)-methyl 4beta-(4-chlorophenyl)-1-methylpiperidine-3alpha-carboxylate, a piperidine-based analog of cocaine. The Journal of Pharmacology and Experimental Therapeutics. 305: 143-50. PMID 12649362 DOI: 10.1124/Jpet.102.046318  0.345
2003 Ghorai SK, Cook C, Davis M, Venkataraman SK, George C, Beardsley PM, Reith ME, Dutta AK. High affinity hydroxypiperidine analogues of 4-(2-benzhydryloxyethyl)-1-(4-fluorobenzyl)piperidine for the dopamine transporter: stereospecific interactions in vitro and in vivo. Journal of Medicinal Chemistry. 46: 1220-8. PMID 12646032 DOI: 10.1021/Jm020275K  0.357
2002 Willmore CB, Bespalov AY, Beardsley PM. Site-selective N-methyl-D-aspartate and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate antagonists produce distinct effects in rats performing complex discriminations. Neurobiology of Learning and Memory. 78: 347-64. PMID 12431422 DOI: 10.1006/Nlme.2002.4077  0.304
2002 Newman JL, Vann RE, May EL, Beardsley PM. Heroin discriminative stimulus effects of methadone, LAAM and other isomers of acetylmethadol in rats. Psychopharmacology. 164: 108-14. PMID 12373424 DOI: 10.1007/S00213-002-1198-8  0.711
2002 Cook CD, Carroll FI, Beardsley PM. RTI 113, a 3-phenyltropane analog, produces long-lasting cocaine-like discriminative stimulus effects in rats and squirrel monkeys. European Journal of Pharmacology. 442: 93-8. PMID 12020686 DOI: 10.1016/S0014-2999(02)01501-7  0.35
2002 Cook CD, Aceto MD, Coop A, Beardsley PM. Effects of the putative antagonist NCS382 on the behavioral pharmacological actions of gammahydroxybutyrate in mice. Psychopharmacology. 160: 99-106. PMID 11862379 DOI: 10.1007/S00213-001-0951-8  0.428
2002 Dutta AK, Davis MC, Fei XS, Beardsley PM, Cook CD, Reith ME. Expansion of structure-activity studies of piperidine analogues of 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine (GBR 12935) compounds by altering substitutions in the N-benzyl moiety and behavioral pharmacology of selected molecules. Journal of Medicinal Chemistry. 45: 654-62. PMID 11806716 DOI: 10.1021/Jm010316X  0.37
2001 Cook CD, Carroll IF, Beardsley PM. Cocaine-like discriminative stimulus effects of novel cocaine and 3-phenyltropane analogs in the rat. Psychopharmacology. 159: 58-63. PMID 11797070 DOI: 10.1007/S002130100891  0.331
2001 Willmore CB, Bespalov AY, Beardsley PM. Competitive and noncompetitive NMDA antagonist effects in rats trained to discriminate lever-press counts. Pharmacology, Biochemistry, and Behavior. 69: 493-502. PMID 11509209 DOI: 10.1016/S0091-3057(01)00568-8  0.35
2001 Dutta AK, Fei XS, Beardsley PM, Newman JL, Reith ME. Structure-activity relationship studies of 4-[2-(diphenylmethoxy)ethyl]-1-benzylpiperidine derivatives and their N-analogues: evaluation of O-and N-analogues and their binding to monoamine transporters. Journal of Medicinal Chemistry. 44: 937-48. PMID 11300876 DOI: 10.1021/Jm000311K  0.589
2000 Bespalov AY, Dravolina OA, Zvartau EE, Beardsley PM, Balster RL. Effects of NMDA receptor antagonists on cocaine-conditioned motor activity in rats. European Journal of Pharmacology. 390: 303-11. PMID 10708738 DOI: 10.1016/S0014-2999(99)00927-9  0.4
1999 Bespalov AY, Tokarz ME, Bowen SE, Balster RL, Beardsley PM. Effects of test conditions on the outcome of place conditioning with morphine and naltrexone in mice. Psychopharmacology. 141: 118-22. PMID 9952035 DOI: 10.1007/S002130050815  0.379
1996 Beardsley PM, Balster RL, Harris LS. Evaluation of the discriminative stimulus and reinforcing effects of gammahydroxybutyrate (GHB). Psychopharmacology. 127: 315-22. PMID 8923566 DOI: 10.1007/s002130050092  0.303
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