Zbigniew Darzynkiewicz - Publications

Affiliations: 
New York Medical College, New York, NY, United States 
Area:
Microbiology Biology, Oncology, Cell Biology

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Year Citation  Score
2020 Ravera S, Ghiotto F, Tenca C, Gugiatti E, Santamaria S, Ledda B, Ibatici A, Cutrona G, Mazzarello AN, Bagnara D, Cardillo M, Zarcone D, Darzynkiewicz Z, Ciccone E, Fais F, et al. Berberine affects mitochondrial activity and cell growth of leukemic cells from chronic lymphocytic leukemia patients. Scientific Reports. 10: 16519. PMID 33020573 DOI: 10.1038/s41598-020-73594-z  0.327
2020 Darzynkiewicz Z. 40 Years of My Venture with CYTOMETRY. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. PMID 32511890 DOI: 10.1002/Cyto.A.24043  0.467
2020 Stobezki R, Titus S, Halicka D, Darzynkiewicz Z, Oktay K. Declining BRCA-Mediated DNA Repair in Sperm Aging and its Prevention by Sphingosine-1-Phosphate. Reproductive Sciences (Thousand Oaks, Calif.). PMID 31916095 DOI: 10.1007/S43032-019-00098-1  0.363
2019 Darzynkiewicz Z, Halicka DH, Zhao H, Li J. Assessment of DNA Susceptibility to Denaturation as a Marker of Chromatin Structure. Current Protocols in Cytometry. 91: e65. PMID 31763788 DOI: 10.1002/Cpcy.65  0.469
2019 Lee MYWT, Zhang S, Wang X, Chao HH, Zhao H, Darzynkiewicz Z, Zhang Z, Lee EYC. Two forms of human DNA polymerase δ: Who does what and why? Dna Repair. 102656. PMID 31326365 DOI: 10.1016/J.Dnarep.2019.102656  0.47
2019 Zhao H, Huang X, Halicka HD, Darzynkiewicz Z. Detection of Histone H2AX Phosphorylation on Ser-139 as an Indicator of DNA Damage. Current Protocols in Cytometry. 89: e55. PMID 31237414 DOI: 10.1002/Cpcy.55  0.459
2019 Deptala A, Halicka HD, Salomon T, Gorczyca W, Seiter K, Feldman EJ, Traganos F, Darzynkiewicz Z. Malignancy: A New Approach to the Analysis of Apoptosis in the Leukemic Subpopulation by Flow Cytometry Using a CD45 Gating Strategy. Hematology (Amsterdam, Netherlands). 4: 113-121. PMID 11399557 DOI: 10.1080/10245332.1999.11746436  0.45
2018 Mishra B, Zhang S, Zhao H, Darzynkiewicz Z, Lee EYC, Lee MYWT, Zhang Z. Discovery of a novel DNA polymerase inhibitor and characterization of its antiproliferative properties. Cancer Biology & Therapy. 1-13. PMID 30427259 DOI: 10.1080/15384047.2018.1529126  0.426
2018 Halicka HD, Li J, Zhao H, Darzynkiewicz Z. Concurrent detection of lysosome and tissue transglutaminase activation in relation to cell cycle position during apoptosis induced by different anticancer drugs. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. PMID 30422397 DOI: 10.1002/Cyto.A.23652  0.485
2018 Smith PJ, Darzynkiewicz Z, Errington RJ. Nuclear cytometry and chromatin organization. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. PMID 30144297 DOI: 10.1002/Cyto.A.23521  0.388
2018 Lucas J, Hsieh TC, Halicka HD, Darzynkiewicz Z, Wu JM. Upregulation of PD‑L1 expression by resveratrol and piceatannol in breast and colorectal cancer cells occurs via HDAC3/p300‑mediated NF‑κB signaling. International Journal of Oncology. PMID 30066852 DOI: 10.3892/Ijo.2018.4512  0.438
2018 Gugiatti E, Tenca C, Ravera S, Fabbi M, Ghiotto F, Mazzarello AN, Bagnara D, Reverberi D, Zarcone D, Cutrona G, Ibatici A, Ciccone E, Darzynkiewicz Z, Fais F, Bruno S. A reversible carnitine palmitoyltransferase I (CPT1) inhibitor offsets chronic lymphocytic leukemia cell proliferation. Haematologica. PMID 29930162 DOI: 10.3324/Haematol.2017.175414  0.38
2017 Darzynkiewicz Z, Huang X, Zhao H. Analysis of Cellular DNA Content by Flow Cytometry. Current Protocols in Immunology. 119: 5.7.1-5.7.20. PMID 29091264 DOI: 10.1002/cpim.36  0.414
2017 Darzynkiewicz Z, Huang X, Zhao H. Analysis of Cellular DNA Content by Flow Cytometry. Current Protocols in Cytometry. 82: 7.5.1-7.5.20. PMID 28967991 DOI: 10.1002/Cpcy.28  0.51
2017 Li C, Park S, Zhang X, Eisenberg LM, Zhao H, Darzynkiewicz Z, Xu D. Nuclear Gene 33/Mig6 Regulates the DNA Damage Response through an ATM-dependent Mechanism. The Journal of Biological Chemistry. PMID 28842482 DOI: 10.1074/Jbc.M117.803338  0.327
2017 Zhao H, Darzynkiewicz Z. Rapid Detection of DNA Strand Breaks in Apoptotic Cells by Flow- and Image-Cytometry. Methods in Molecular Biology (Clifton, N.J.). 1644: 139-149. PMID 28710760 DOI: 10.1007/978-1-4939-7187-9_12  0.413
2017 Darzynkiewicz Z, Zhao H, Dorota Halicka H, Pozarowski P, Lee B. Fluorochrome-Labeled Inhibitors of Caspases: Expedient In Vitro and In Vivo Markers of Apoptotic Cells for Rapid Cytometric Analysis. Methods in Molecular Biology (Clifton, N.J.). 1644: 61-73. PMID 28710753 DOI: 10.1007/978-1-4939-7187-9_5  0.42
2017 Zhao H, Halicka HD, Garcia J, Li J, Darzynkiewicz Z. ATM Activation and H2AX Phosphorylation Induced by Genotoxic Agents Assessed by Flow- and Laser Scanning Cytometry. Methods in Molecular Biology (Clifton, N.J.). 1599: 183-196. PMID 28477120 DOI: 10.1007/978-1-4939-6955-5_14  0.502
2017 Galkowski D, Ratajczak MZ, Kocki J, Darzynkiewicz Z. Of Cytometry, Stem Cells and Fountain of Youth. Stem Cell Reviews. PMID 28364326 DOI: 10.1007/S12015-017-9733-5  0.346
2017 Ratajczak MZ, Bartke A, Darzynkiewicz Z. Prolonged Growth Hormone/Insulin/Insulin-like Growth Factor Nutrient Response Signaling Pathway as a Silent Killer of Stem Cells and a Culprit in Aging. Stem Cell Reviews. PMID 28229284 DOI: 10.1007/S12015-017-9728-2  0.322
2017 Halicka D, Zhao H, Li J, Garcia J, Podhorecka M, Darzynkiewicz Z. DNA Damage Response Resulting from Replication Stress Induced by Synchronization of Cells by Inhibitors of DNA Replication: Analysis by Flow Cytometry. Methods in Molecular Biology (Clifton, N.J.). 1524: 107-119. PMID 27815899 DOI: 10.1007/978-1-4939-6603-5_7  0.533
2017 Li C, Park S, Zhang X, Eisenberg L, Zhao H, Darzynkiewicz Z, Xu D. Abstract 5524: Gene 33/Mig6 regulates apoptosis and the DNA damage response through independent mechanisms Cancer Research. 77: 5524-5524. DOI: 10.1158/1538-7445.Am2017-5524  0.37
2017 Lucas JP, Wu JM, Hsieh T, Darzynkiewicz Z, Halicka-Ambroziak HD. Abstract 2654: Resveratrol and piceatannol synergistically induce PDL1 expression Cancer Research. 77: 2654-2654. DOI: 10.1158/1538-7445.Am2017-2654  0.309
2016 Halicka HD, Garcia J, Li J, Zhao H, Darzynkiewicz Z. Synergy of 2-deoxy-D-glucose combined with berberine in inducing the lysosome/autophagy and transglutaminase activation-facilitated apoptosis. Apoptosis : An International Journal On Programmed Cell Death. PMID 27796611 DOI: 10.1007/S10495-016-1315-5  0.508
2016 Rybak P, Hoang A, Bujnowicz L, Bernas T, Berniak K, ZarÄ Bski MA, Darzynkiewicz Z, Dobrucki J. Low level phosphorylation of histone H2AX on serine 139 (γH2AX) is not associated with DNA double-strand breaks. Oncotarget. PMID 27391338 DOI: 10.18632/Oncotarget.10411  0.43
2016 Pierzyńska-Mach A, Szczurek A, Cella Zanacchi F, Pennacchietti F, Drukała J, Diaspro A, Cremer C, Darzynkiewicz Z, Dobrucki JW. Subnuclear localization, rates and effectiveness of UVC-induced unscheduled DNA synthesis visualized by fluorescence widefield, confocal and super-resolution microscopy. Cell Cycle (Georgetown, Tex.). 15: 1156-67. PMID 27097376 DOI: 10.1080/15384101.2016.1158377  0.424
2016 Park S, Li C, Zhao H, Darzynkiewicz Z, Xu D. Gene 33/Mig6 inhibits hexavalent chromium-induced DNA damage and cell transformation in human lung epithelial cells. Oncotarget. PMID 26760771 DOI: 10.18632/Oncotarget.6866  0.379
2015 Hanly EK, Tuli NY, Bednarczyk RB, Suriano R, Geliebter J, Moscatello AL, Darzynkiewicz Z, Tiwari RK. Hyperactive ERK and persistent mTOR signaling characterize vemurafenib resistance in papillary thyroid cancer cells. Oncotarget. PMID 26735176 DOI: 10.18632/Oncotarget.6779  0.307
2015 Darzynkiewicz Z. Rapid and simple detection of gero-suppressive agents. Oncotarget. 6: 23050-1. PMID 26375365 DOI: 10.18632/Oncotarget.5455  0.419
2015 Hanly EK, Bednarczyk RB, Tuli NY, Moscatello AL, Halicka HD, Li J, Geliebter J, Darzynkiewicz Z, Tiwari RK. mTOR inhibitors sensitize thyroid cancer cells to cytotoxic effect of vemurafenib. Oncotarget. 6: 39702-13. PMID 26284586 DOI: 10.18632/Oncotarget.4052  0.39
2015 Darzynkiewicz Z, Zhao H, Zhang S, Lee MY, Lee EY, Zhang Z. Initiation and termination of DNA replication during S phase in relation to cyclins D1, E and A, p21WAF1, Cdt1 and the p12 subunit of DNA polymerase δ revealed in individual cells by cytometry. Oncotarget. 6: 11735-11750. PMID 26059433 DOI: 10.18632/Oncotarget.4149  0.417
2015 Jones ME, O'Connell T, Gupta A, Zhao H, Iacob C, Moscatello A, Shin E, Darzynkiewicz Z, Tiwari RK, Geliebter J. Abstract 708: Androgen receptor activation inhibits papillary thyroid carcinoma cell cycle progression Cancer Research. 75: 708-708. DOI: 10.1158/1538-7445.Am2015-708  0.382
2015 Darzynkiewicz Z, Zhao H, Zhang S, Lee MYWT, Lee EYC, Zhang Z. Initiation and termination of DNA replication during S phase in relation to cyclins D1, E and A, p21<sup>WAF1</sup>, Cdt1 and the p12 subunit of DNA polymerase d revealed in individual cells by cytometry Oncotarget. 6: 11735-11750.  0.307
2014 Zhao H, Zhang S, Xu D, Lee MY, Zhang Z, Lee EY, Darzynkiewicz Z. Expression of the p12 subunit of human DNA polymerase δ (Pol δ), CDK inhibitor p21(WAF1), Cdt1, cyclin A, PCNA and Ki-67 in relation to DNA replication in individual cells. Cell Cycle (Georgetown, Tex.). 13: 3529-40. PMID 25483089 DOI: 10.4161/15384101.2014.958910  0.439
2014 Zhao H, Darzynkiewicz Z. Attenuation of replication stress-induced premature cellular senescence to assess anti-aging modalities. Current Protocols in Cytometry / Editorial Board, J. Paul Robinson, Managing Editor ... [Et Al.]. 69: 9.47.1-9.47.10. PMID 24984966 DOI: 10.1002/0471142956.Cy0947S69  0.417
2014 Li B, Zhao H, Rybak P, Dobrucki JW, Darzynkiewicz Z, Kimmel M. Different rates of DNA replication at early versus late S-phase sections: multiscale modeling of stochastic events related to DNA content/EdU (5-ethynyl-2'deoxyuridine) incorporation distributions. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 85: 785-97. PMID 24894899 DOI: 10.1002/Cyto.A.22484  0.446
2014 Smolewski P, Witkowska M, Zwolinska M, Cebula-Obrzut B, Majchrzak A, Jeske A, Darzynkiewicz Z, Ardelt W, Ardelt B, Robak T. Cytotoxic activity of the amphibian ribonucleases onconase and r-amphinase on tumor cells from B cell lymphoproliferative disorders. International Journal of Oncology. 45: 419-25. PMID 24789756 DOI: 10.3892/Ijo.2014.2405  0.37
2014 Darzynkiewicz Z, Zhao H, Halicka HD, Li J, Lee YS, Hsieh TC, Wu JM. In search of antiaging modalities: evaluation of mTOR- and ROS/DNA damage-signaling by cytometry. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 85: 386-99. PMID 24677687 DOI: 10.1002/Cyto.A.22452  0.4
2014 Lee MY, Zhang S, Lin SH, Wang X, Darzynkiewicz Z, Zhang Z, Lee EY. The tail that wags the dog: p12, the smallest subunit of DNA polymerase δ, is degraded by ubiquitin ligases in response to DNA damage and during cell cycle progression. Cell Cycle (Georgetown, Tex.). 13: 23-31. PMID 24300032 DOI: 10.4161/Cc.27407  0.407
2014 Hanly EK, Tuli NY, Suriano R, Bednarczyk R, Darzynkiewicz Z, Moscatello AL, Shin EJ, Geliebter J, Tiwari RK. Abstract 3709: Resistance mechanisms to targeted molecular therapy in thyroid cancer Cancer Research. 74: 3709-3709. DOI: 10.1158/1538-7445.Am2014-3709  0.313
2014 MacEwan ME, O'Connell T, Zhao H, Iacob C, Suslina N, Moscatello A, Shin E, Tiwari R, Darzynkiewicz Z, Geliebter J. Abstract 2122: Androgen decreases proliferation of thyroid cancer cells Cancer Research. 74: 2122-2122. DOI: 10.1158/1538-7445.Am2014-2122  0.347
2014 Stobezki R, Titus S, Halicka D, Darzynkiewicz Z, Oktay K. Declining DNA double strand break repair results in male reproductive aging Fertility and Sterility. 102. DOI: 10.1016/J.Fertnstert.2014.07.378  0.32
2013 Akagi J, Skommer J, Matuszek A, Takeda K, Fujimura Y, Khoshmanesh K, Kalantar-Zadeh K, Mitchell A, Errington R, Smith PJ, Darzynkiewicz Z, Wlodkowic D. Multivariate analysis of apoptotic markers versus cell cycle phase in living human cancer cells by microfluidic cytometry. Proceedings of Spie--the International Society For Optical Engineering. 8615. PMID 24386542 DOI: 10.1117/12.2001474  0.397
2013 Majchrzak A, Witkowska M, Mędra A, Zwolińska M, Bogusz J, Cebula-Obrzut B, Darzynkiewicz Z, Robak T, Smolewski P. In vitro cytotoxicity of ranpirnase (onconase) in combination with components of R-CHOP regimen against diffuse large B cell lymphoma (DLBCL) cell line. PostȩPy Higieny I Medycyny DośWiadczalnej (Online). 67: 1166-72. PMID 24379257 DOI: 10.5604/17322693.1078386  0.409
2013 Zhao H, Halicka HD, Li J, Biela E, Berniak K, Dobrucki J, Darzynkiewicz Z. DNA damage signaling, impairment of cell cycle progression, and apoptosis triggered by 5-ethynyl-2'-deoxyuridine incorporated into DNA. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 83: 979-88. PMID 24115313 DOI: 10.1002/Cyto.A.22396  0.547
2013 Wong A, Zhang S, Mordue D, Wu JM, Zhang Z, Darzynkiewicz Z, Lee EY, Lee MY. PDIP38 is translocated to the spliceosomes/nuclear speckles in response to UV-induced DNA damage and is required for UV-induced alternative splicing of MDM2. Cell Cycle (Georgetown, Tex.). 12: 3184-93. PMID 23989611 DOI: 10.4161/Cc.26221  0.425
2013 Tarnok A, Darzynkiewicz Z. New insights into cell cycle and DNA damage response machineries through high-resolution AMICO quantitative imaging cytometry Cell Proliferation. 46: 497-500. PMID 23952744 DOI: 10.1111/Cpr.12050  0.384
2013 Zhang S, Zhao H, Darzynkiewicz Z, Zhou P, Zhang Z, Lee EY, Lee MY. A novel function of CRL4(Cdt2): regulation of the subunit structure of DNA polymerase δ in response to DNA damage and during the S phase. The Journal of Biological Chemistry. 288: 29550-61. PMID 23913683 DOI: 10.1074/Jbc.M113.490466  0.324
2013 Bernas T, Berniak K, Rybak P, Zarębski M, Zhao H, Darzynkiewicz Z, Dobrucki JW. Analysis of spatial correlations between patterns of DNA damage response and DNA replication in nuclei of cells subjected to replication stress or oxidative damage. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 83: 925-32. PMID 23900967 DOI: 10.1002/Cyto.A.22325  0.441
2013 Berniak K, Rybak P, Bernas T, Zarebski M, Biela E, Zhao H, Darzynkiewicz Z, Dobrucki JW. Relationship between DNA damage response, initiated by camptothecin or oxidative stress, and DNA replication, analyzed by quantitative 3D image analysis Cytometry Part A. 83: 913-924. PMID 23846844 DOI: 10.1002/Cyto.A.22327  0.418
2013 Wlodkowic D, Akagi J, Dobrucki J, Errington R, Smith PJ, Takeda K, Darzynkiewicz Z. Kinetic viability assays using DRAQ7 probe. Current Protocols in Cytometry / Editorial Board, J. Paul Robinson, Managing Editor ... [Et Al.]. Unit 9.41. PMID 23835805 DOI: 10.1002/0471142956.Cy0941S65  0.473
2013 Darzynkiewicz Z. Perturbation of nucleotide metabolism--the driving force of oncogene-induced senescence. Oncotarget. 4: 649-50. PMID 23660114 DOI: 10.18632/Oncotarget.1023  0.449
2013 Zhao H, Darzynkiewicz Z. Biomarkers of cell senescence assessed by imaging cytometry. Methods in Molecular Biology (Clifton, N.J.). 965: 83-92. PMID 23296652 DOI: 10.1007/978-1-62703-239-1_5  0.479
2013 Akagi J, Kordon M, Zhao H, Matuszek A, Dobrucki J, Errington R, Smith PJ, Takeda K, Darzynkiewicz Z, Wlodkowic D. Real-time cell viability assays using a new anthracycline derivative DRAQ7®. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 83: 227-34. PMID 23165976 DOI: 10.1002/Cyto.A.22228  0.465
2013 Pozarowski P, Holden E, Darzynkiewicz Z. Laser scanning cytometry: principles and applications-an update. Methods in Molecular Biology (Clifton, N.J.). 931: 187-212. PMID 23027005 DOI: 10.1007/978-1-62703-056-4_11  0.407
2013 Stobezki R, Titus S, Darzynkiewicz Z, Oktay K. Male mice show significant age-induced decline in sperm DNA integrity Fertility and Sterility. 100. DOI: 10.1016/J.Fertnstert.2013.07.138  0.302
2012 Halicka HD, Zhao H, Li J, Lee YS, Hsieh TC, Wu JM, Darzynkiewicz Z. Potential anti-aging agents suppress the level of constitutive mTOR- and DNA damage- signaling. Aging. 4: 952-65. PMID 23363784  0.316
2012 Darzynkiewicz Z. Running m(o)TOR with the brakes on leads to catastrophe at mitosis. Cell Cycle (Georgetown, Tex.). 11: 4494. PMID 23222065 DOI: 10.4161/Cc.22932  0.507
2012 Darzynkiewicz Z, Zhao H, Halicka HD, Rybak P, Dobrucki J, Wlodkowic D. DNA damage signaling assessed in individual cells in relation to the cell cycle phase and induction of apoptosis. Critical Reviews in Clinical Laboratory Sciences. 49: 199-217. PMID 23137030 DOI: 10.3109/10408363.2012.738808  0.487
2012 McKenna E, Traganos F, Zhao H, Darzynkiewicz Z. Persistent DNA damage caused by low levels of mitomycin C induces irreversible cell senescence. Cell Cycle (Georgetown, Tex.). 11: 3132-40. PMID 22871735 DOI: 10.4161/Cc.21506  0.506
2012 Chea J, Zhang S, Zhao H, Zhang Z, Lee EY, Darzynkiewicz Z, Lee MY. Spatiotemporal recruitment of human DNA polymerase delta to sites of UV damage. Cell Cycle (Georgetown, Tex.). 11: 2885-95. PMID 22801543 DOI: 10.4161/Cc.21280  0.379
2012 Darzynkiewicz Z. Cycling into future: mass cytometry for the cell-cycle analysis. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 81: 546-8. PMID 22692796 DOI: 10.1002/Cyto.A.22080  0.434
2012 Halicka HD, Zhao H, Li J, Traganos F, Studzinski GP, Darzynkiewicz Z. Attenuation of constitutive DNA damage signaling by 1,25-dihydroxyvitamin D3. Aging. 4: 270-8. PMID 22498490  0.301
2012 Zhao H, Rybak P, Dobrucki J, Traganos F, Darzynkiewicz Z. Relationship of DNA damage signaling to DNA replication following treatment with DNA topoisomerase inhibitors camptothecin/topotecan, mitoxantrone, or etoposide. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 81: 45-51. PMID 22140093 DOI: 10.1002/Cyto.A.21172  0.445
2012 Gorczyca W, Bruno S, Darzynkiewicz R, Gong J, Darzynkiewicz Z. DNA strand breaks occurring during apoptosis - their early insitu detection by the terminal deoxynucleotidyl transferase and nick translation assays and prevention by serine protease inhibitors. International Journal of Oncology. 1: 639-48. PMID 21584593 DOI: 10.3892/Ijo.1.6.639  0.466
2012 Traganos F, Knuttihotz J, Hotz M, Gorczyca W, Ardelt B, Darzynkiewicz Z. The protein-kinase-C inhibitor h7 blocks normal human lymphocyte stimulation and induces apoptosis of both normal lymphocytes and leukemia molt-4 cells. International Journal of Oncology. 2: 47-59. PMID 21573514 DOI: 10.3892/Ijo.2.1.47  0.496
2012 Gong J, Traganos F, Darzynkiewicz Z. Expression of cyclins-B and cyclins-e in individual molt-4 cells and in stimulated human-lymphocytes during their progression through the cell-cycle. International Journal of Oncology. 3: 1037-42. PMID 21573469 DOI: 10.3892/Ijo.3.6.1037  0.433
2012 Gorczyca W, Ardelt B, Darzynkiewicz Z. Different rates of degradation of the proliferation-associated nuclear and nucleolar antigens during apoptosis of hl-60 cells induced by DNA topoisomerase inhibitors. International Journal of Oncology. 3: 627-34. PMID 21573410 DOI: 10.3892/Ijo.3.4.627  0.501
2012 Tillotson J, Darzynkiewicz Z, Cohen L, Ronai Z. Effects of linoleic-Acid on mammary-tumor cell-proliferation are associated with changes in p53 protein expression. International Journal of Oncology. 3: 81-7. PMID 21573330 DOI: 10.3892/Ijo.3.1.81  0.428
2012 Li X, Traganos F, Melamed M, Darzynkiewicz Z. Detection of 5-bromo-2-deoxyuridine incorporated into DNA by labeling strand breaks induced by photolysis (sbip). International Journal of Oncology. 4: 1157-61. PMID 21567032 DOI: 10.3892/Ijo.4.6.1157  0.506
2012 Gong J, Traganos F, Darzynkiewicz Z. Use of the cyclin e restriction point to map cell arrest in g(1)-induced by N-butyrate, cycloheximide, staurosporine, lovastatin, mimosine and quercetin. International Journal of Oncology. 4: 803-8. PMID 21566985 DOI: 10.3892/Ijo.4.4.803  0.439
2012 Halicka H, Ardelt B, Juan G, Mittelman A, Chen S, Traganos F, Darzynkiewicz Z. Apoptosis and cell cycle effects induced by extracts of the Chinese herbal preparation PC SPES. International Journal of Oncology. 11: 437-48. PMID 21528230 DOI: 10.3892/Ijo.11.3.437  0.449
2011 Halicka HD, Zhao H, Li J, Traganos F, Zhang S, Lee M, Darzynkiewicz Z. Genome protective effect of metformin as revealed by reduced level of constitutive DNA damage signaling. Aging. 3: 1028-38. PMID 22067284  0.307
2011 Darzynkiewicz Z. Redundancy in response to DNA damage: the key to protection of genome integrity. Cell Cycle (Georgetown, Tex.). 10: 3425. PMID 22024932 DOI: 10.4161/Cc.10.20.17525  0.46
2011 Zhao H, Dobrucki J, Rybak P, Traganos F, Dorota Halicka H, Darzynkiewicz Z. Induction of DNA damage signaling by oxidative stress in relation to DNA replication as detected using "click chemistry". Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 79: 897-902. PMID 21905210 DOI: 10.1002/Cyto.A.21137  0.463
2011 Soleimani R, Heytens E, Darzynkiewicz Z, Oktay K. Mechanisms of chemotherapy-induced human ovarian aging: double strand DNA breaks and microvascular compromise. Aging. 3: 782-93. PMID 21869459 DOI: 10.18632/Aging.100363  0.401
2011 Darzynkiewicz Z, Halicka HD, Zhao H, Podhorecka M. Cell synchronization by inhibitors of DNA replication induces replication stress and DNA damage response: analysis by flow cytometry. Methods in Molecular Biology (Clifton, N.J.). 761: 85-96. PMID 21755443 DOI: 10.1007/978-1-61779-182-6_6  0.505
2011 Darzynkiewicz Z, Traganos F, Zhao H, Halicka HD, Skommer J, Wlodkowic D. Analysis of individual molecular events of DNA damage response by flow- and image-assisted cytometry. Methods in Cell Biology. 103: 115-47. PMID 21722802 DOI: 10.1016/B978-0-12-385493-3.00006-1  0.465
2011 Wlodkowic D, Telford W, Skommer J, Darzynkiewicz Z. Apoptosis and beyond: cytometry in studies of programmed cell death. Methods in Cell Biology. 103: 55-98. PMID 21722800 DOI: 10.1016/B978-0-12-385493-3.00004-8  0.446
2011 Hu L, Liu X, Chervona Y, Yang F, Tang MS, Darzynkiewicz Z, Dai W. Chromium induces chromosomal instability, which is partly due to deregulation of BubR1 and Emi1, two APC/C inhibitors. Cell Cycle (Georgetown, Tex.). 10: 2373-9. PMID 21670593 DOI: 10.4161/Cc.10.14.16310  0.353
2011 Wlodkowic D, Khoshmanesh K, Sharpe JC, Darzynkiewicz Z, Cooper JM. Apoptosis goes on a chip: advances in the microfluidic analysis of programmed cell death. Analytical Chemistry. 83: 6439-46. PMID 21630641 DOI: 10.1021/Ac200588G  0.37
2011 Zhao H, Li J, Traganos F, Halicka HD, Zarebski M, Dobrucki J, Darzynkiewicz Z. Cell fixation in zinc salt solution is compatible with DNA damage response detection by phospho-specific antibodies. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 79: 470-6. PMID 21595014 DOI: 10.1002/Cyto.A.21060  0.51
2011 Wlodkowic D, Faley S, Darzynkiewicz Z, Cooper JM. Real-time cytotoxicity assays Methods in Molecular Biology (Clifton, N.J.). 731: 285-291. PMID 21516415 DOI: 10.1007/978-1-61779-080-5_23  0.341
2011 Wlodkowic D, Skommer J, Darzynkiewicz Z. Rapid quantification of cell viability and apoptosis in B-cell lymphoma cultures using cyanine SYTO probes. Methods in Molecular Biology (Clifton, N.J.). 740: 81-9. PMID 21468970 DOI: 10.1007/978-1-61779-108-6_10  0.412
2011 Darzynkiewicz Z, Traganos F, Zhao H, Halicka HD, Li J. Cytometry of DNA replication and RNA synthesis: Historical perspective and recent advances based on "click chemistry". Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 79: 328-37. PMID 21425239 DOI: 10.1002/Cyto.A.21048  0.477
2011 Hao S, Zhao H, Darzynkiewicz Z, Battula S, Ferreri NR. Differential regulation of NFAT5 by NKCC2 isoforms in medullary thick ascending limb (mTAL) cells. American Journal of Physiology. Renal Physiology. 300: F966-75. PMID 21228109 DOI: 10.1152/Ajprenal.00408.2010  0.362
2011 Nowicki TS, Zhao H, Darzynkiewicz Z, Moscatello A, Shin E, Schantz S, Tiwari RK, Geliebter J. Downregulation of uPAR inhibits migration, invasion, proliferation, FAK/PI3K/Akt signaling and induces senescence in papillary thyroid carcinoma cells. Cell Cycle (Georgetown, Tex.). 10: 100-7. PMID 21191179 DOI: 10.4161/Cc.10.1.14362  0.361
2011 Darzynkiewicz Z, Smolewski P, Holden E, Luther E, Henriksen M, François M, Leifert W, Fenech M. Laser scanning cytometry for automation of the micronucleus assay. Mutagenesis. 26: 153-61. PMID 21164197 DOI: 10.1093/Mutage/Geq069  0.423
2011 Darzynkiewicz Z, Pozarowski P, Lee BW, Johnson GL. Fluorochrome-labeled inhibitors of caspases: convenient in vitro and in vivo markers of apoptotic cells for cytometric analysis. Methods in Molecular Biology (Clifton, N.J.). 682: 103-14. PMID 21057924 DOI: 10.1007/978-1-60327-409-8_9  0.515
2011 Darzynkiewicz Z, Zhao H. Detection of DNA strand breaks in apoptotic cells by flow- and image-cytometry. Methods in Molecular Biology (Clifton, N.J.). 682: 91-101. PMID 21057923 DOI: 10.1007/978-1-60327-409-8_8  0.517
2011 Holden E, Newmark J, Wong C, François M, Fenech M, Leifert W, Darzynkiewicz Z. Abstract LB-336: High-content, high-throughput imaging cytometry for fully automated DNA damage analysis Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Lb-336  0.471
2011 Nowicki TS, Zhao H, Darzynkiewicz Z, Moscatello A, Schantz S, Shin E, Tiwari RK, Geliebter J. Abstract 1406: Downregulation of uPAR inhibits migration, invasion, proliferation, FAK/PI3K/Akt signaling, and induces senescence in papillary thyroid carcinoma cells Cancer Research. 71: 1406-1406. DOI: 10.1158/1538-7445.Am2011-1406  0.349
2010 Zhao H, Halicka HD, Traganos F, Jorgensen E, Darzynkiewicz Z. New biomarkers probing depth of cell senescence assessed by laser scanning cytometry. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 77: 999-1007. PMID 20939035 DOI: 10.1002/Cyto.A.20983  0.518
2010 Darzynkiewicz Z. Cytometry of the cell cycle: In search for perfect methodology for DNA content analysis in tissue specimens. Cell Cycle (Georgetown, Tex.). 9: 3395-6. PMID 20861663 DOI: 10.4161/Cc.9.17.13015  0.515
2010 Darzynkiewicz Z, Halicka HD, Zhao H. Analysis of cellular DNA content by flow and laser scanning cytometry. Advances in Experimental Medicine and Biology. 676: 137-47. PMID 20687474 DOI: 10.1007/978-1-4419-6199-0_9  0.488
2010 Darzynkiewicz Z. Guarding genome integrity in stem cells. Cell Cycle (Georgetown, Tex.). 9: 2271-2. PMID 20581438 DOI: 10.4161/Cc.9.12.12024  0.433
2010 Skommer J, Darzynkiewicz Z, Wlodkowic D. Cell death goes LIVE: technological advances in real-time tracking of cell death. Cell Cycle (Georgetown, Tex.). 9: 2330-41. PMID 20519963 DOI: 10.4161/Cc.9.12.11911  0.381
2010 Darzynkiewicz Z. Critical aspects in analysis of cellular DNA content. Current Protocols in Cytometry / Editorial Board, J. Paul Robinson, Managing Editor ... [Et Al.]. Unit7.2. PMID 20373495 DOI: 10.1002/0471142956.Cy0702S52  0.407
2010 Ikeda M, Kurose A, Takatori E, Sugiyama T, Traganos F, Darzynkiewicz Z, Sawai T. DNA damage detected with gammaH2AX in endometrioid adenocarcinoma cell lines. International Journal of Oncology. 36: 1081-8. PMID 20372780 DOI: 10.3892/Ijo_00000589  0.521
2010 Wlodkowic D, Skommer J, Darzynkiewicz Z. Cytometry in cell necrobiology revisited. Recent advances and new vistas. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 77: 591-606. PMID 20235235 DOI: 10.1002/Cyto.A.20889  0.428
2010 Zhao H, Oczos J, Janowski P, Trembecka D, Dobrucki J, Darzynkiewicz Z, Wlodkowic D. Rationale for the real-time and dynamic cell death assays using propidium iodide. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 77: 399-405. PMID 20131407 DOI: 10.1002/Cyto.A.20867  0.511
2010 Oka K, Tanaka T, Enoki T, Yoshimura K, Ohshima M, Kubo M, Murakami T, Gondou T, Minami Y, Takemoto Y, Harada E, Tsushimi T, Li TS, Traganos F, Darzynkiewicz Z, et al. DNA damage signaling is activated during cancer progression in human colorectal carcinoma. Cancer Biology & Therapy. 9: 246-52. PMID 20023412 DOI: 10.4161/Cbt.9.3.10751  0.396
2010 Zhao H, Traganos F, Darzynkiewicz Z. Kinetics of the UV-induced DNA damage response in relation to cell cycle phase. Correlation with DNA replication. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 77: 285-93. PMID 20014310 DOI: 10.1002/Cyto.A.20839  0.498
2010 Smolewski P, Zwoliñska M, Cebula-Obrzut B, Majchrzak A, Misiewicz M, Jeske A, Darzynkiewicz Z, Ardelt W, Ardelt B, Saxena SK, Muniz C, Robak T. Antitumor Activity of Amphibian Ribonucleases, Onconase and R-Amhinase, on Tumor Cells From B-Cell Lymphoproliferative Disorders Blood. 116: 2842-2842. DOI: 10.1182/Blood.V116.21.2842.2842  0.405
2009 Darzynkiewicz Z. When senescence masquerades as DNA damage: is DNA replication stress the culprit? Cell Cycle (Georgetown, Tex.). 8: 3810-1. PMID 19887905 DOI: 10.4161/Cc.8.23.10368  0.419
2009 Darzynkiewicz Z, Traganos F, Wlodkowic D. Impaired DNA damage response--an Achilles' heel sensitizing cancer to chemotherapy and radiotherapy. European Journal of Pharmacology. 625: 143-50. PMID 19836377 DOI: 10.1016/J.Ejphar.2009.05.032  0.476
2009 Ardelt W, Ardelt B, Darzynkiewicz Z. Ribonucleases as potential modalities in anticancer therapy. European Journal of Pharmacology. 625: 181-9. PMID 19825371 DOI: 10.1016/J.Ejphar.2009.06.067  0.381
2009 Halicka HD, Smart DJ, Traganos F, Williams GM, Darzynkiewicz Z. Fluoroquinolones lower constitutive H2AX and ATM phosphorylation in TK6 lymphoblastoid cells via modulation of the intracellular redox status. Pharmacological Reports : Pr. 61: 711-8. PMID 19815954 DOI: 10.1016/S1734-1140(09)70124-0  0.446
2009 Darzynkiewicz Z, Halicka DH, Tanaka T. Cytometric assessment of DNA damage induced by DNA topoisomerase inhibitors. Methods in Molecular Biology (Clifton, N.J.). 582: 145-53. PMID 19763948 DOI: 10.1007/978-1-60761-340-4_12  0.429
2009 Halicka HD, Darzynkiewicz Z, Teodori L. Attenuation of constitutive ATM activation and H2AX phosphorylation in human leukemic TK6 cells by their exposure to static magnetic field. Cell Cycle (Georgetown, Tex.). 8: 3238-40. PMID 19755848 DOI: 10.4161/Cc.8.19.9598  0.3
2009 Zhao H, Albino AP, Jorgensen E, Traganos F, Darzynkiewicz Z. DNA damage response induced by tobacco smoke in normal human bronchial epithelial and A549 pulmonary adenocarcinoma cells assessed by laser scanning cytometry. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 75: 840-7. PMID 19658174 DOI: 10.1002/Cyto.A.20778  0.461
2009 Wlodkowic D, Skommer J, Darzynkiewicz Z. Flow cytometry-based apoptosis detection. Methods in Molecular Biology (Clifton, N.J.). 559: 19-32. PMID 19609746 DOI: 10.1007/978-1-60327-017-5_2  0.458
2009 Wlodkowic D, Skommer J, McGuinness D, Hillier C, Darzynkiewicz Z. ER-Golgi network--a future target for anti-cancer therapy. Leukemia Research. 33: 1440-7. PMID 19595459 DOI: 10.1016/J.Leukres.2009.05.025  0.386
2009 Wlodkowic D, Skommer J, McGuinness D, Faley S, Kolch W, Darzynkiewicz Z, Cooper JM. Chip-based dynamic real-time quantification of drug-induced cytotoxicity in human tumor cells Analytical Chemistry. 81: 6952-6959. PMID 19572560 DOI: 10.1021/Ac9010217  0.396
2009 Halicka HD, Zhao H, Podhorecka M, Traganos F, Darzynkiewicz Z. Cytometric detection of chromatin relaxation, an early reporter of DNA damage response. Cell Cycle (Georgetown, Tex.). 8: 2233-7. PMID 19502789 DOI: 10.4161/Cc.8.14.8984  0.481
2009 Darzynkiewicz Z. Forever young, slim and fit: rapamycin to the rescue. Cell Cycle (Georgetown, Tex.). 8: 1820-1. PMID 19471126 DOI: 10.4161/Cc.8.12.8967  0.462
2009 Halicka HD, Ozkaynak MF, Levendoglu-Tugal O, Sandoval C, Seiter K, Kajstura M, Traganos F, Jayabose S, Darzynkiewicz Z. DNA damage response as a biomarker in treatment of leukemias. Cell Cycle (Georgetown, Tex.). 8: 1720-4. PMID 19411853 DOI: 10.4161/Cc.8.11.8598  0.405
2009 Tanaka T, Halicka D, Traganos F, Darzynkiewicz Z. Cytometric analysis of DNA damage: phosphorylation of histone H2AX as a marker of DNA double-strand breaks (DSBs). Methods in Molecular Biology (Clifton, N.J.). 523: 161-8. PMID 19381940 DOI: 10.1007/978-1-59745-190-1_11  0.456
2009 Zhao H, Traganos F, Dobrucki J, Wlodkowic D, Darzynkiewicz Z. Induction of DNA damage response by the supravital probes of nucleic acids. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 75: 510-9. PMID 19373929 DOI: 10.1002/Cyto.A.20727  0.468
2009 Darzynkiewicz Z. An interview with Dr. Zbigniew Darzynkiewicz on his highly cited paper published in Cell Cycle. Cell Cycle (Georgetown, Tex.). 8: 1471-2. PMID 19372731 DOI: 10.4161/Cc.8.10.8623  0.403
2009 Hao S, Zhao H, Darzynkiewicz Z, Battula S, Ferreri NR. Expression and function of NFAT5 in medullary thick ascending limb (mTAL) cells. American Journal of Physiology. Renal Physiology. 296: F1494-503. PMID 19369291 DOI: 10.1152/Ajprenal.90436.2008  0.429
2009 Halicka HD, Mitlitski V, Heeter J, Balazs EA, Darzynkiewicz Z. Attenuation of the oxidative burst-induced DNA damage in human leukocytes by hyaluronan. International Journal of Molecular Medicine. 23: 695-9. PMID 19360330 DOI: 10.3892/Ijmm_00000182  0.334
2009 Sato Y, Kurose A, Ogawa A, Ogasawara K, Traganos F, Darzynkiewicz Z, Sawai T. Diversity of DNA damage response of astrocytes and glioblastoma cell lines with various p53 status to treatment with etoposide and temozolomide. Cancer Biology & Therapy. 8: 452-7. PMID 19305157 DOI: 10.4161/Cbt.8.5.7740  0.512
2009 Wlodkowic D, Skommer J, Faley S, Darzynkiewicz Z, Cooper JM. Dynamic analysis of apoptosis using cyanine SYTO probes: From classical to microfluidic cytometry Experimental Cell Research. 315: 1706-1714. PMID 19298813 DOI: 10.1016/J.Yexcr.2009.03.006  0.429
2008 Zhao H, Ardelt B, Ardelt W, Shogen K, Darzynkiewicz Z. The cytotoxic ribonuclease onconase targets RNA interference (siRNA) Cell Cycle. 7: 3258-3261. PMID 18927512 DOI: 10.4161/Cc.7.20.6855  0.383
2008 Darzynkiewicz Z. Pushing cancer cells to commit suicide: Is 072RB, the new BH3 mimetic, up to the job? Cell Cycle. 7: 3111. PMID 18843203 DOI: 10.4161/Cc.7.20.7063  0.397
2008 Zhao H, Traganos F, Darzynkiewicz Z. Phosphorylation of p53 on Ser15 during cell cycle caused by Topo I and Topo II inhibitors in relation to ATM and Chk2 activation. Cell Cycle (Georgetown, Tex.). 7: 3048-55. PMID 18802408 DOI: 10.4161/Cc.7.19.6750  0.419
2008 Juan G, Darzynkiewicz Z. Detection of mitotic cells. Current Protocols in Cytometry. Unit 7.24. PMID 18770801 DOI: 10.1002/0471142956.Cy0724S28  0.465
2008 Pozarowski P, Grabarek J, Darzynkiewicz Z. Flow cytometry of apoptosis. Current Protocols in Cytometry. Unit 7.19. PMID 18770781 DOI: 10.1002/0471142956.Cy0719S25  0.43
2008 Juan G, Darzynkiewicz Z. Bivariate analysis of DNA content and expression of cyclin proteins. Current Protocols in Cytometry. Unit 7.9. PMID 18770736 DOI: 10.1002/0471142956.Cy0709S04  0.402
2008 Darzynkiewicz Z, Juan G. Analysis of DNA denaturation. Current Protocols in Cytometry. Unit 7.8. PMID 18770735 DOI: 10.1002/0471142956.Cy0708S03  0.365
2008 Darzynkiewicz Z, Juan G. Analysis of DNA content and BrdU incorporation. Current Protocols in Cytometry. Unit 7.7. PMID 18770734 DOI: 10.1002/0471142956.Cy0707S02  0.397
2008 Darzynkiewicz Z, Juan G. DNA content measurement for DNA ploidy and cell cycle analysis. Current Protocols in Cytometry. Unit 7.5. PMID 18770732 DOI: 10.1002/0471142956.Cy0705S00  0.47
2008 Darzynkiewicz Z, Juan G. Analysis of DNA content and DNA strand breaks for detection of apoptotic cells. Current Protocols in Cytometry. Unit 7.4. PMID 18770731 DOI: 10.1002/0471142956.cy0704s00  0.363
2008 Darzynkiewicz Z, Juan G. Overview of nucleic acid analysis. Current Protocols in Cytometry. Unit 7.1. PMID 18770721 DOI: 10.1002/0471142956.Cy0701S00  0.314
2008 Ardelt W, Shogen K, Darzynkiewicz Z. Onconase and amphinase, the antitumor ribonucleases from Rana pipiens oocytes Current Pharmaceutical Biotechnology. 9: 215-225. PMID 18673287 DOI: 10.2174/138920108784567245  0.425
2008 Wlodkowic D, Darzynkiewicz Z. Please do not disturb: Destruction of chromatin structure by supravital nucleic acid probes revealed by a novel assay of DNA-histone interaction Cytometry Part A. 73: 877-879. PMID 18671237 DOI: 10.1002/Cyto.A.20622  0.436
2008 Darzynkiewicz Z. Broken beyond repair. Damaging DNA in glioblastoma cells with radiation and camptothecin Cancer Biology and Therapy. 7: 374-375. PMID 18614857 DOI: 10.4161/Cbt.7.3.5581  0.386
2008 Zhao H, Tanaka T, Mitlitski V, Heeter J, Balazs EA, Darzynkiewicz Z. Protective effect of hyaluronate on oxidative DNA damage in WI-38 and A549 cells International Journal of Oncology. 32: 1159-1167. PMID 18497977 DOI: 10.3892/Ijo_32_6_1159  0.431
2008 Zhao H, Traganos F, Darzynkiewicz Z. Kinetics of histone H2AX phosphorylation and Chk2 activation in A549 cells treated with topotecan and mitoxantrone in relation to the cell cycle phase. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 73: 480-9. PMID 18459160 DOI: 10.1002/Cyto.A.20574  0.52
2008 Ita M, Halicka HD, Tanaka T, Kurose A, Ardelt B, Shogen K, Darzynkiewicz Z. Remarkable enhancement of cytotoxicity of onconase and cepharanthine when used in combination on various tumor cell lines Cancer Biology and Therapy. 7: 1104-1108. PMID 18443430 DOI: 10.4161/Cbt.7.7.6172  0.393
2008 Wlodkowic D, Skommer J, Hillier C, Darzynkiewicz Z. Multiparameter detection of apoptosis using red-excitable SYTO probes. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 73: 563-9. PMID 18431792 DOI: 10.1002/Cyto.A.20564  0.388
2008 Pietrzak M, Halicka HD, Wieczorek Z, Wieczorek J, Darzynkiewicz Z. Attenuation of acridine mutagen ICR-191 - DNA interactions and DNA damage by the mutagen interceptor chlorophyllin Biophysical Chemistry. 135: 69-75. PMID 18423964 DOI: 10.1016/J.Bpc.2008.03.004  0.441
2008 Smart DJ, Halicka HD, Schmuck G, Traganos F, Darzynkiewicz Z, Williams GM. Assessment of DNA double-strand breaks and gammaH2AX induced by the topoisomerase II poisons etoposide and mitoxantrone. Mutation Research. 641: 43-7. PMID 18423498 DOI: 10.1016/J.Mrfmmm.2008.03.005  0.417
2008 Zhao H, Traganos F, Albino AP, Darzynkiewicz Z. Oxidative stress induces cell cycle-dependent Mre11 recruitment, ATM and Chk2 activation and histone H2AX phosphorylation. Cell Cycle (Georgetown, Tex.). 7: 1490-5. PMID 18418078 DOI: 10.4161/Cc.7.10.5963  0.495
2008 Wang X, Yang Y, Duan Q, Jiang N, Huang Y, Darzynkiewicz Z, Dai W. sSgo1, a major splice variant of Sgo1, functions in centriole cohesion where it is regulated by Plk1. Developmental Cell. 14: 331-41. PMID 18331714 DOI: 10.1016/J.Devcel.2007.12.007  0.319
2008 Darzynkiewicz Z, Galkowski D, Zhao H. Analysis of apoptosis by cytometry using TUNEL assay Methods. 44: 250-254. PMID 18314056 DOI: 10.1016/J.Ymeth.2007.11.008  0.48
2008 Darzynkiewicz Z. There's more than one way to skin a cat: Yet another way to assess mitotic index by cytometry Cytometry Part A. 73: 386-387. PMID 18307275 DOI: 10.1002/Cyto.A.20543  0.508
2008 Halicka HD, Ita M, Tanaka T, Kurose A, Darzynkiewicz Z. Biscoclaurine alkaloid cepharanthine protects DNA in TK6 lymphoblastoid cells from constitutive oxidative damage Pharmacological Reports. 60: 93-100. PMID 18276990  0.318
2008 Wlodkowic D, Skommer J, Darzynkiewicz Z. SYTO probes in the cytometry of tumor cell death Cytometry Part A. 73: 496-507. PMID 18260152 DOI: 10.1002/Cyto.A.20535  0.459
2008 Pozarowski P, Grabarek J, Darzynkiewicz Z. Flow cytometry of apoptosis. Current Protocols in Cell Biology. Unit 18.8. PMID 18228448 DOI: 10.1002/0471143030.Cb1808S21  0.501
2008 Darzynkiewicz Z, Juan G, Bedner E. Determining cell cycle stages by flow cytometry. Current Protocols in Cell Biology. Unit 8.4. PMID 18228389 DOI: 10.1002/0471143030.Cb0804S01  0.491
2008 Chen S, Gao J, Halicka HD, Traganos F, Darzynkiewicz Z. Down-regulation of androgen-receptor and PSA by phytochemicals. International Journal of Oncology. 32: 405-11. PMID 18202763 DOI: 10.3892/Ijo.32.2.405  0.351
2008 Smart DJ, Halicka HD, Traganos F, Darzynkiewicz Z, Williams GM. Ciprofloxacin-induced G2 arrest and apoptosis in TK6 lymphoblastoid cells is not dependent on DNA double-strand break formation. Cancer Biology & Therapy. 7: 113-9. PMID 18059176 DOI: 10.1182/Blood.V110.11.4094.4094  0.54
2008 Smolewski P, Linke-Szewczyk A, Cebula B, Shogen K, Ardelt W, Darzynkiewicz Z, Robak T. Activity of Anti-Tumor Endoribonucleases, Onconase (ranpirnase) and R-Amphinase in Chronic Lymphocytic Leukemia Blood. 112: 4205-4205. DOI: 10.1182/Blood.V112.11.4205.4205  0.386
2008 Smolewski P, Cebula B, Zwolinska M, Linke-Szewczyk A, Wozniak D, Shogen K, Ardelt W, Darzynkiewicz Z, Robak T. Ex Vivo Cytotoxic Activity of Endoribonucleases, Onconase (ranpirnase) and R-Amphinase, against Acute Myeloblastic Leukemia Cells Blood. 112: 4010-4010. DOI: 10.1182/Blood.V112.11.4010.4010  0.402
2007 Ardelt B, Ardelt W, Pozarowski P, Kunicki J, Shogen K, Darzynkiewicz Z. Cytostatic and cytotoxic properties of amphinase: A novel cytotoxic ribonuclease from Rana pipiens oocytes Cell Cycle. 6: 3097-3102. PMID 18073526 DOI: 10.4161/Cc.6.24.5045  0.476
2007 Hsieh TC, Traganos F, Darzynkiewicz Z, Wu JM. The 2,6-disubstituted purine reversine induces growth arrest and polyploidy in human cancer cells. International Journal of Oncology. 31: 1293-300. PMID 17982654 DOI: 10.3892/Ijo.31.6.1293  0.485
2007 Tadi K, Ashok BT, Chen Y, Banerjee D, Wysocka-Skrzela B, Konopa J, Darzynkiewicz Z, Tiwari RK. Pre-clinical evaluation of 1-nitroacridine derived chemotherapeutic agent that has preferential cytotoxic activity towards prostate cancer. Cancer Biology & Therapy. 6: 1632-7. PMID 17921700 DOI: 10.4161/Cbt.6.10.4790  0.393
2007 Zhao H, Tanaka T, Halicka HD, Traganos F, Zarebski M, Dobrucki J, Darzynkiewicz Z. Cytometric assessment of DNA damage by exogenous and endogenous oxidants reports aging-related processes. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 71: 905-14. PMID 17879239 DOI: 10.1002/Cyto.A.20469  0.45
2007 Ardelt B, Juan G, Burfeind P, Salomon T, Wu JM, Hsieh TC, Li X, Sperry R, Pozarowski P, Shogen K, Ardelt W, Darzynkiewicz Z. Onconase, an anti-tumor ribonuclease suppresses intracellular oxidative stress International Journal of Oncology. 31: 663-669. PMID 17671695 DOI: 10.3892/Ijo.31.3.663  0.407
2007 Darzynkiewicz Z, Pozarowski P. All that glitters is not gold: All that FLICA binds is not caspase. A caution in data interpretation - and new opportunities Cytometry Part A. 71: 536-537. PMID 17640078 DOI: 10.1002/Cyto.A.20425  0.391
2007 Schulenburg C, Ardelt B, Ardelt W, Arnold U, Shogen K, Ulbrich-Hofmann R, Darzynkiewicz Z. The interdependence between catalytic activity, conformational stability, and cytotoxicity of onconase. Cancer Biology & Therapy. 6: 1233-9. PMID 17637563 DOI: 10.4161/Cbt.6.8.4423  0.411
2007 Tanaka T, Huang X, Halicka HD, Zhao H, Traganos F, Albino AP, Dai W, Darzynkiewicz Z. Cytometry of ATM activation and histone H2AX phosphorylation to estimate extent of DNA damage induced by exogenous agents. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 71: 648-61. PMID 17622968 DOI: 10.1002/Cyto.A.20426  0.476
2007 Tanaka T, Huang X, Jorgensen E, Gietl D, Traganos F, Darzynkiewicz Z, Albino AP. ATM activation accompanies histone H2AX phosphorylation in A549 cells upon exposure to tobacco smoke. Bmc Cell Biology. 8: 26. PMID 17594478 DOI: 10.1186/1471-2121-8-26  0.393
2007 Halicka HD, Ardelt B, Shogen K, Darzynkiewicz Z. Mild hyperthermia predisposes tumor cells to undergo apoptosis upon treatment with onconase International Journal of Oncology. 30: 841-847. PMID 17332922 DOI: 10.3892/Ijo.30.4.841  0.39
2007 Tanaka T, Halicka HD, Traganos F, Seiter K, Darzynkiewicz Z. Induction of ATM activation, histone H2AX phosphorylation and apoptosis by etoposide: relation to cell cycle phase. Cell Cycle (Georgetown, Tex.). 6: 371-6. PMID 17297310 DOI: 10.4161/Cc.6.3.3835  0.522
2007 Kajstura M, Halicka HD, Pryjma J, Darzynkiewicz Z. Discontinuous fragmentation of nuclear DNA during apoptosis revealed by discrete "Sub-G1" peaks on DNA content histograms Cytometry Part A. 71: 125-131. PMID 17252584 DOI: 10.1002/Cyto.A.20357  0.5
2007 Tanaka T, Kajstura M, Halicka HD, Traganos F, Darzynkiewicz Z. Constitutive histone H2AX phosphorylation and ATM activation are strongly amplified during mitogenic stimulation of lymphocytes Cell Proliferation. 40: 1-13. PMID 17227291 DOI: 10.1111/J.1365-2184.2007.00417.X  0.426
2007 Lin JH, Takano T, Arcuino G, Wang X, Hu F, Darzynkiewicz Z, Nunes M, Goldman SA, Nedergaard M. Purinergic signaling regulates neural progenitor cell expansion and neurogenesis. Developmental Biology. 302: 356-66. PMID 17188262 DOI: 10.1016/J.Ydbio.2006.09.017  0.357
2006 Tanaka T, Halicka HD, Traganos F, Darzynkiewicz Z. Phosphorylation of histone H2AX on Ser 139 and activation of ATM during oxidative burst in phorbol ester-treated human leukocytes. Cell Cycle (Georgetown, Tex.). 5: 2671-5. PMID 17106266 DOI: 10.4161/Cc.5.22.3472  0.456
2006 Mandecki W, Ardelt B, Coradetti T, Davidowitz H, AFlint JA, Huang Z, MKopacka WM, Lin X, Wang Z, Darzynkiewicz Z. Microtransponders, the miniature RFID electronic chips, as platforms for cell growth in cytotoxicity assays. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 69: 1097-105. PMID 17051582 DOI: 10.1002/Cyto.A.20344  0.301
2006 Tanaka T, Halicka HD, Huang X, Traganos F, Darzynkiewicz Z. Constitutive histone H2AX phosphorylation and ATM activation, the reporters of DNA damage by endogenous oxidants. Cell Cycle (Georgetown, Tex.). 5: 1940-5. PMID 16940754 DOI: 10.4161/Cc.5.17.3191  0.445
2006 Tanaka T, Kurose A, Huang X, Traganos F, Dai W, Darzynkiewicz Z. Extent of constitutive histone H2AX phosphorylation on Ser-139 varies in cells with different TP53 status Cell Proliferation. 39: 313-323. PMID 16872365 DOI: 10.1111/J.1365-2184.2006.00387.X  0.457
2006 Tanaka T, Kurose A, Halicka HD, Huang X, Traganos F, Darzynkiewicz Z. Nitrogen oxide-releasing aspirin induces histone H2AX phosphorylation, ATM activation and apoptosis preferentially in S-phase cells: involvement of reactive oxygen species. Cell Cycle (Georgetown, Tex.). 5: 1669-74. PMID 16861926 DOI: 10.4161/Cc.5.15.3100  0.48
2006 Huang X, Tanaka T, Kurose A, Traganos F, Darzynkiewicz Z. Constitutive histone H2AX phosphorylation on Ser-139 in cells untreated by genotoxic agents is cell-cycle phase specific and attenuated by scavenging reactive oxygen species. International Journal of Oncology. 29: 495-501. PMID 16820894 DOI: 10.3892/Ijo.29.2.495  0.511
2006 Huang X, Kurose A, Tanaka T, Traganos F, Dai W, Darzynkiewicz Z. Activation of ATM and histone H2AX phosphorylation induced by mitoxantrone but not by topotecan is prevented by the antioxidant N-acetyl-L-cysteine. Cancer Biology & Therapy. 5: 959-64. PMID 16760673 DOI: 10.4161/Cbt.5.8.2878  0.513
2006 Pozarowski P, Holden E, Darzynkiewicz Z. Laser scanning cytometry: principles and applications. Methods in Molecular Biology (Clifton, N.J.). 319: 165-92. PMID 16719355 DOI: 10.1007/978-1-59259-993-6_8  0.428
2006 Albino AP, Huang X, Jorgensen ED, Gietl D, Traganos F, Darzynkiewicz Z. Induction of DNA double-strand breaks in A549 and normal human pulmonary epithelial cells by cigarette smoke is mediated by free radicals. International Journal of Oncology. 28: 1491-505. PMID 16685450  0.329
2006 Darzynkiewicz Z, Huang X, Okafuji M. Detection of DNA strand breaks by flow and laser scanning cytometry in studies of apoptosis and cell proliferation (DNA replication) Methods in Molecular Biology (Clifton, N.J.). 314: 81-93. PMID 16673876 DOI: 10.1385/1-59259-973-7:081  0.478
2006 Huang X, Darzynkiewicz Z. Cytometric assessment of histone H2AX phosphorylation: a reporter of DNA damage Methods in Molecular Biology (Clifton, N.J.). 314: 73-80. PMID 16673875 DOI: 10.1385/1-59259-973-7:073  0.466
2006 Kurose A, Tanaka T, Huang X, Traganos F, Darzynkiewicz Z. Synchronization in the cell cycle by inhibitors of DNA replication induces histone H2AX phosphorylation: An indication of DNA damage Cell Proliferation. 39: 231-240. PMID 16672000 DOI: 10.1111/J.1365-2184.2006.00380.X  0.514
2006 Pietrzak M, Wieczorek Z, Wieczorek J, Darzynkiewicz Z. The "interceptor" properties of chlorophyllin measured within the three-component system: Intercalator-DNA-chlorophyllin Biophysical Chemistry. 123: 11-19. PMID 16650923 DOI: 10.1016/J.Bpc.2006.03.018  0.362
2006 Tanaka T, Kurose A, Halicka HD, Traganos F, Darzynkiewicz Z. 2-deoxy-D-glucose reduces the level of constitutive activation of ATM and phosphorylation of histone H2AX. Cell Cycle (Georgetown, Tex.). 5: 878-82. PMID 16628006 DOI: 10.4161/Cc.5.8.2681  0.469
2006 Huang X, Kurose A, Tanaka T, Traganos F, Dai W, Darzynkiewicz Z. Sequential phosphorylation of Ser-10 on histone H3 and ser-139 on histone H2AX and ATM activation during premature chromosome condensation: relationship to cell-cycle phase and apoptosis. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 69: 222-9. PMID 16528736 DOI: 10.1002/Cyto.A.20257  0.345
2006 Kurose A, Tanaka T, Huang X, Traganos F, Dai W, Darzynkiewicz Z. Effects of hydroxyurea and aphidicolin on phosphorylation of ataxia telangiectasia mutated on Ser 1981 and histone H2AX on Ser 139 in relation to cell cycle phase and induction of apoptosis. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 69: 212-21. PMID 16528719 DOI: 10.1002/Cyto.A.20241  0.434
2006 Jiang N, Wang X, Jhanwar-Uniyal M, Darzynkiewicz Z, Dai W. Polo box domain of Plk3 functions as a centrosome localization signal, overexpression of which causes mitotic arrest, cytokinesis defects, and apoptosis. The Journal of Biological Chemistry. 281: 10577-82. PMID 16478733 DOI: 10.1074/Jbc.M513156200  0.342
2006 Fang Y, Liu T, Wang X, Yang YM, Deng H, Kunicki J, Traganos F, Darzynkiewicz Z, Lu L, Dai W. BubR1 is involved in regulation of DNA damage responses Oncogene. 25: 3598-3605. PMID 16449973 DOI: 10.1038/sj.onc.1209392  0.332
2006 Tanaka T, Kurose A, Huang X, Dai W, Darzynkiewicz Z. ATM activation and histone H2AX phosphorylation as indicators of DNA damage by DNA topoisomerase I inhibitor topotecan and during apoptosis Cell Proliferation. 39: 49-60. PMID 16426422 DOI: 10.1111/J.1365-2184.2006.00364.X  0.499
2006 Gupte RS, Sampson V, Traganos F, Darzynkiewicz Z, Lee MY. Cyclic AMP regulates the expression and nuclear translocation of RFC40 in MCF7 cells. Experimental Cell Research. 312: 796-806. PMID 16413017 DOI: 10.1016/J.Yexcr.2005.11.033  0.438
2006 Chen J, Huang X, Halicka D, Brodsky S, Avram A, Eskander J, Bloomgarden NA, Darzynkiewicz Z, Goligorsky MS. Contribution of p16INK4a and p21CIP1 pathways to induction of premature senescence of human endothelial cells: permissive role of p53. American Journal of Physiology. Heart and Circulatory Physiology. 290: H1575-86. PMID 16243918 DOI: 10.1152/Ajpheart.00364.2005  0.327
2006 Albino AP, Huang X, Jorgensen ED, Gietl D, Traganos F, Darzynkiewicz Z. Induction of DNA double-strand breaks in A549 and normal human pulmonary epithelial cells by cigarette smoke is mediated by free radicals. International Journal of Oncology. 28: 1491-1505. DOI: 10.3892/Ijo.28.6.1491  0.44
2006 Halicka DH, Ozkaynak FM, Seiter K, Kajstura MA, Liu D, Tanaka T, Traganos F, Darzynkiewicz Z. Assessing DNA Damage Ex Vivo Induced by Chemotherapy Targeting Topoisomerase Inhibitors in Acute Leukemias. Blood. 108: 4372-4372. DOI: 10.1182/Blood.V108.11.4372.4372  0.444
2006 Darzynkiewicz Z, Pozarowski P, Gloria J. Cell cycle analysis by flow and laser-scanning cytometry Cell Biology, Four-Volume Set. 1: 279-289. DOI: 10.1016/B978-012164730-8/50035-6  0.424
2005 Jain K, Roy U, Ardelt B, Krishna UM, Falck JR, Pozarowski P, Kunicki J, Darzynkiewicz Z, Balazy M. 5E, 8Z, HZ, 14Z-eicosatetraenoic acid, a novel transisomer of arachidonic acid, causes G1 phase arrest and induces apoptosis of HL-60 cells International Journal of Oncology. 27: 1177-1185. PMID 16211211 DOI: 10.3892/Ijo.27.5.1177  0.486
2005 Kurose A, Tanaka T, Huang X, Halicka HD, Traganos F, Dai W, Darzynkiewicz Z. Assessment of ATM phosphorylation on Ser-1981 induced by DNA topoisomerase I and II inhibitors in relation to Ser-139-histone H2AX phosphorylation, cell cycle phase, and apoptosis. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 68: 1-9. PMID 16184611 DOI: 10.1002/Cyto.A.20186  0.466
2005 Friedrich TD, Bedner E, Darzynkiewicz Z, Lehman JM. Distinct patterns of MCM protein binding in nuclei of S phase and rereplicating SV40-infected monkey kidney cells. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 68: 10-8. PMID 16184610 DOI: 10.1002/Cyto.A.20185  0.443
2005 Huang X, Halicka HD, Traganos F, Tanaka T, Kurose A, Darzynkiewicz Z. Cytometric assessment of DNA damage in relation to cell cycle phase and apoptosis. Cell Proliferation. 38: 223-43. PMID 16098182 DOI: 10.1111/J.1365-2184.2005.00344.X  0.499
2005 Huang X, Dai W, Darzynkiewicz Z. Enforced adhesion of hematopoietic cells to culture dish induces endomitosis and polyploidy Cell Cycle. 4: 801-805. PMID 15908784 DOI: 10.4161/Cc.4.6.1695  0.501
2005 Demidenko ZN, Halicka D, Kunicki J, McCubrey JA, Darzynkiewicz Z, Blagosklonny MV. Selective killing of adriamycin-resistant (G2 checkpoint-deficient and MRP1-expressing) cancer cells by docetaxel Cancer Research. 65: 4401-4407. PMID 15899832 DOI: 10.1158/0008-5472.Can-04-4428  0.431
2005 Gupte RS, Pozarowski P, Grabarek J, Traganos F, Darzynkiewicz Z, Lee MY. RIalpha influences cellular proliferation in cancer cells by transporting RFC40 into the nucleus. Cancer Biology & Therapy. 4: 429-37. PMID 15846072 DOI: 10.4161/Cbt.4.4.1621  0.389
2005 Chen S, Gao J, Halicka HD, Huang X, Traganos F, Darzynkiewicz Z. The cytostatic and cytotoxic effects of oridonin (Rubescenin), a diterpenoid from Rabdosia rubescens, on tumor cells of different lineage. International Journal of Oncology. 26: 579-88. PMID 15703811 DOI: 10.3892/Ijo.26.3.579  0.526
2005 Halicka HD, Huang X, Traganos F, King MA, Dai W, Darzynkiewicz Z. Histone H2AX phosphorylation after cell irradiation with UV-B: relationship to cell cycle phase and induction of apoptosis. Cell Cycle (Georgetown, Tex.). 4: 339-45. PMID 15655354 DOI: 10.4161/Cc.4.2.1486  0.508
2005 Huang X, Lee B, Johnson G, Naleway J, Guzikowski A, Dai W, Darzynkiewicz Z. Novel assay utilizing fluorochrome-tagged physostigmine (Ph-F) to in situ detect active acetylcholinesterase (AChE) induced during apoptosis Cell Cycle. 4: 140-147. PMID 15611638 DOI: 10.4161/Cc.4.1.1322  0.378
2005 Halicka D, Ozkaynak FM, Huang X, Traganos F, Darzynkiewicz Z. Pilot Study of the Feasibility of Assessing DNA Damage and Apoptosis Induced by Chemotherapy in Children with Acute Leukemias. Blood. 106: 4587-4587. DOI: 10.1182/blood.v106.11.4587.4587  0.308
2004 Darzynkiewicz Z, Juan G, Srour EF. Differential staining of DNA and RNA. Current Protocols in Cytometry / Editorial Board, J. Paul Robinson, Managing Editor ... [Et Al.]. Unit 7.3. PMID 18770805 DOI: 10.1002/0471142956.Cy0703S30  0.447
2004 Huang X, Halicka HD, Darzynkiewicz Z. Detection of histone H2AX phosphorylation on Ser-139 as an indicator of DNA damage (DNA double-strand breaks). Current Protocols in Cytometry / Editorial Board, J. Paul Robinson, Managing Editor ... [Et Al.]. Unit 7.27. PMID 18770804 DOI: 10.1002/0471142956.Cy0727S30  0.472
2004 Darzynkiewicz Z, Huang X. Analysis of cellular DNA content by flow cytometry. Current Protocols in Immunology / Edited by John E. Coligan ... [Et Al.]. Unit 5.7. PMID 18432930 DOI: 10.1002/0471142735.Im0507S60  0.51
2004 Darzynkiewicz Z, Huang X, Okafuji M, King MA. Cytometric Methods to Detect Apoptosis Methods in Cell Biology. 75: 307-341. PMID 15603431 DOI: 10.1016/S0091-679X(04)75012-8  0.459
2004 Tsai SY, Ardelt B, Hsieh TC, Darzynkiewicz Z, Shogen K, Wu JM. Treatment of Jurkat acute T-lymphocytic leukemia cells by onconase (Ranpirnase) is accompanied by an altered nucleocytoplasmic distribution and reduced expression of transcription factor NF-kappaB International Journal of Oncology. 25: 1745-1752. PMID 15547713 DOI: 10.3892/Ijo.25.6.1745  0.469
2004 King MA, Halicka HD, Darzynkiewicz Z. Pro- and anti-apoptotic effects of an inhibitor of chymotrypsin-like serine proteases Cell Cycle. 3: 1566-1571. PMID 15539954 DOI: 10.4161/Cc.3.12.1276  0.439
2004 Huang X, King MA, Halicka HD, Traganos F, Okafuji M, Darzynkiewicz Z. Histone H2AX phosphorylation induced by selective photolysis of BrdU-labeled DNA with UV light: relation to cell cycle phase. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 62: 1-7. PMID 15455410 DOI: 10.1002/Cyto.A.20086  0.439
2004 Fu Y, Hsieh TC, Guo J, Kunicki J, Lee MY, Darzynkiewicz Z, Wu JM. Licochalcone-A, a novel flavonoid isolated from licorice root (Glycyrrhiza glabra), causes G2 and late-G1 arrests in androgen-independent PC-3 prostate cancer cells. Biochemical and Biophysical Research Communications. 322: 263-70. PMID 15313200 DOI: 10.1016/J.Bbrc.2004.07.094  0.421
2004 Blagosklonny MV, Darzynkiewicz Z, Halicka HD, Pozarowski P, Demidenko ZN, Barry JJ, Kamath KR, Herrmann RA. Paclitaxel induces primary and postmitotic G1 arrest in human arterial smooth muscle cells. Cell Cycle (Georgetown, Tex.). 3: 1050-6. PMID 15254417  0.399
2004 Albino AP, Huang X, Jorgensen E, Yang J, Gietl D, Traganos F, Darzynkiewicz Z. Induction of H2AX phosphorylation in pulmonary cells by tobacco smoke: a new assay for carcinogens. Cell Cycle (Georgetown, Tex.). 3: 1062-8. PMID 15254392 DOI: 10.4161/Cc.3.8.988  0.365
2004 Pozarowski P, Darzynkiewicz Z. Analysis of cell cycle by flow cytometry Methods in Molecular Biology (Clifton, N.J.). 281: 301-311. PMID 15220539 DOI: 10.1385/1-59259-811-0:301  0.512
2004 Huang X, Okafuji M, Traganos F, Luther E, Holden E, Darzynkiewicz Z. Assessment of histone H2AX phosphorylation induced by DNA topoisomerase I and II inhibitors topotecan and mitoxantrone and by the DNA cross-linking agent cisplatin. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 58: 99-110. PMID 15057963 DOI: 10.1002/Cyto.A.20018  0.409
2004 Darzynkiewicz Z, Crissman H, Jacobberger JW. Cytometry of the cell cycle: cycling through history. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 58: 21-32. PMID 14994216 DOI: 10.1002/Cyto.A.20003  0.503
2004 Ruan Q, Wang Q, Xie S, Fang Y, Darzynkiewicz Z, Guan K, Jhanwar-Uniyal M, Dai W. Polo-like kinase 3 is Golgi localized and involved in regulating Golgi fragmentation during the cell cycle. Experimental Cell Research. 294: 51-9. PMID 14980500 DOI: 10.1016/J.Yexcr.2003.10.022  0.371
2004 Pozarowski P, Huang X, Gong RW, Priebe W, Darzynkiewicz Z. Simple, semiautomatic assay of cytostatic and cytotoxic effects of antitumor drugs by laser scanning cytometry: effects of the bis-intercalator WP631 on growth and cell cycle of T-24 cells. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 57: 113-9. PMID 14750133 DOI: 10.1002/Cyto.A.10121  0.491
2004 Halicka HD, Seiter K, Feldman EJ, Traganos F, Mittelman A, Ahmed T, Darzynkiewicz Z. Cell cycle specificity of apoptosis during treatment of leukaemias. Apoptosis : An International Journal On Programmed Cell Death. 2: 25-39. PMID 14646562 DOI: 10.1023/A:1026431524236  0.494
2004 Wang Q, Liu T, Fang Y, Xie S, Huang X, Mahmood R, Ramaswamy G, Sakamoto KM, Darzynkiewicz Z, Xu M, Dai W. BUBR1 deficiency results in abnormal megakaryopoiesis. Blood. 103: 1278-85. PMID 14576056 DOI: 10.1182/Blood-2003-06-2158  0.323
2004 Pozarowski P, Huang X, Halicka DH, Lee B, Johnson G, Darzynkiewicz Z. Interactions of fluorochrome-labeled caspase inhibitors with apoptotic cells: a caution in data interpretation. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 55: 50-60. PMID 12938188 DOI: 10.1002/Cyto.A.10074  0.4
2004 Pozarowski P, Halicka DH, Darzynkiewicz Z. NF-kappaB inhibitor sesquiterpene parthenolide induces concurrently atypical apoptosis and cell necrosis: difficulties in identification of dead cells in such cultures. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 54: 118-24. PMID 12879458 DOI: 10.1002/Cyto.A.10057  0.433
2004 Pozarowski P, Halicka DH, Darzynkiewicz Z. Cell cycle effects and caspase-dependent and independent death of HL-60 and Jurkat cells treated with the inhibitor of NF-kappaB parthenolide. Cell Cycle (Georgetown, Tex.). 2: 377-83. PMID 12851492  0.355
2004 Halicka HD, Huang X, Traganos F, King MA, Dai W, Darzynkiewicz Z. Histone H2AX Phosphorylation after Cell Irradiation with UV-B: Relationship to Cell Cycle Phase and Induction of Apoptosis Cell Cycle. 4: 338-344. DOI: 10.4161/cc.4.2.1486  0.331
2004 Blagosklonny MV, Darzynkiewicz Z, Halicka HD, Pozarowski P, Demidenko ZN, Barry JJ, Kamath KR, Herrmann RA. Paclitaxel Induces Primary and Postmitotic G1 Arrest in Human Arterial Smooth Muscle Cells Cell Cycle. 3: 1048-1054. DOI: 10.4161/Cc.3.8.986  0.487
2004 Huang X, Ruan Q, Fang Y, Traganos F, Darzynkiewicz Z, Dai W. Physical and Functional Interactions between Mitotic Kinases during Polyploidization and Megakaryocytic Differentiation Cell Cycle. 3: 944-949. DOI: 10.4161/Cc.3.7.973  0.342
2004 Smolewski P, Cebula B, Wierzbicka D, Linke A, Jamroziak K, Blagosklonny MV, Darzynkiewicz Z, Robak T. Rapamycin, Inhibitor of Mtor Kinase, Sensitizes Leukemia Cells to Fludarabine-Induced Apoptosis, but Protects Survival of Normal Lymphocytes. Blood. 104: 4497-4497. DOI: 10.1182/Blood.V104.11.4497.4497  0.511
2004 Halicka DH, Huang X, Ozkaynak FM, Seiter K, Traganos F, Darzynkiewicz Z. DNA Damage Induced by DNA Topoisomerase I- and Topoisomerase II- Inhibitors Detected by Histone H2AX Phosphorylation in Leukemic Cells. Blood. 104: 4240-4240. DOI: 10.1182/Blood.V104.11.4240.4240  0.529
2003 Lee BW, Johnson GL, Hed SA, Darzynkiewicz Z, Talhouk JW, Mehrotra S. DEVDase detection in intact apoptotic cells using the cell permeant fluorogenic substrate, (z-DEVD)2-cresyl violet. Biotechniques. 35: 1080-5. PMID 14628683 DOI: 10.2144/03355Pf01  0.388
2003 Darzynkiewicz Z, Juan G, Traganos F. Cytometry of cell cycle regulatory proteins. Progress in Cell Cycle Research. 5: 533-42. PMID 14593748  0.386
2003 Huang X, Traganos F, Darzynkiewicz Z. DNA damage induced by DNA topoisomerase I- and topoisomerase II-inhibitors detected by histone H2AX phosphorylation in relation to the cell cycle phase and apoptosis. Cell Cycle (Georgetown, Tex.). 2: 614-9. PMID 14504478  0.45
2003 Abraham NG, Kushida T, McClung J, Weiss M, Quan S, Lafaro R, Darzynkiewicz Z, Wolin M. Heme oxygenase-1 attenuates glucose-mediated cell growth arrest and apoptosis in human microvessel endothelial cells. Circulation Research. 93: 507-14. PMID 12933701 DOI: 10.1161/01.Res.0000091828.36599.34  0.437
2003 Smolewski P, Darzynkiewicz Z, Robak T. Caspase-mediated cell death in hematological malignancies: theoretical considerations, methods of assessment, and clinical implications. Leukemia & Lymphoma. 44: 1089-104. PMID 12916860 DOI: 10.1080/1042819031000077007  0.379
2003 Haider A, Lee I, Grabarek J, Darzynkiewicz Z, Ferreri NR. Dual functionality of cyclooxygenase-2 as a regulator of tumor necrosis factor-mediated G1 shortening and nitric oxide-mediated inhibition of vascular smooth muscle cell proliferation. Circulation. 108: 1015-21. PMID 12912810 DOI: 10.1161/01.Cir.0000085211.97972.2C  0.318
2003 Blagosklonny MV, Darzynkiewicz Z. Why Iressa failed: toward novel use of kinase inhibitors (outlook). Cancer Biology & Therapy. 2: 137-40. PMID 12750551 DOI: 10.4161/Cbt.2.2.286  0.311
2003 Haider AS, Grabarek J, Eng B, Pedraza P, Ferreri NR, Balazs EA, Darzynkiewicz Z. In vitro model of "wound healing" analyzed by laser scanning cytometry: accelerated healing of epithelial cell monolayers in the presence of hyaluronate. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 53: 1-8. PMID 12701127 DOI: 10.1002/Cyto.A.10032  0.353
2003 Ardelt B, Ardelt W, Darzynkiewicz Z. Cytotoxic ribonucleases and RNA interference (RNAi). Cell Cycle (Georgetown, Tex.). 2: 22-4. PMID 12695680 DOI: 10.4161/Cc.2.1.232  0.311
2003 Blagosklonny MV, Darzynkiewicz Z. Cyclotherapy: protection of normal cells and unshielding of cancer cells. Cell Cycle (Georgetown, Tex.). 1: 375-82. PMID 12548008 DOI: 10.4161/Cc.1.6.259  0.422
2003 Hsieh TC, Kunicki J, Darzynkiewicz Z, Wu JM. Effects of extracts of Coriolus versicolor (I'm-Yunity) on cell-cycle progression and expression of interleukins-1 beta,-6, and -8 in promyelocytic HL-60 leukemic cells and mitogenically stimulated and nonstimulated human lymphocytes. Journal of Alternative and Complementary Medicine (New York, N.Y.). 8: 591-602. PMID 12470440 DOI: 10.1089/107555302320825101  0.332
2003 Blagosklonny MV, Darzynkiewicz Z, Figg WD. Flavopiridol inversely affects p21(WAF1/CIP1) and p53 and protects p21-sensitive cells from paclitaxel. Cancer Biology & Therapy. 1: 420-5. PMID 12432259 DOI: 10.4161/Cbt.1.4.21  0.367
2003 Grabarek J, Ardelt B, Kunicki J, Darzynkiewicz Z. Detection of in situ activation of transglutaminase during apoptosis: correlation with the cell cycle phase by multiparameter flow and laser scanning cytometry. Cytometry. 49: 83-9. PMID 12357464 DOI: 10.1002/Cyto.10150  0.376
2003 Grabarek J, Amstad P, Darzynkiewicz Z. Use of fluorescently labeled caspase inhibitors as affinity labels to detect activated caspases. Human Cell. 15: 1-12. PMID 12126059 DOI: 10.1111/J.1749-0774.2002.Tb00094.X  0.424
2003 Huang X, Traganos F, Darzynkiewicz Z. DNA Damage Induced by DNA Topoisomerase I- and Topoisomerase II- Inhibitors Detected by Histone H2AXphosphorylation in Relation to the Cell Cycle Phase and Apoptosis Cell Cycle. 2: 613-618. DOI: 10.4161/Cc.2.6.565  0.522
2003 Pozarowski P, Halicka DH, Darzynkiewicz Z. Cell Cycle Effects and Caspase-Dependent and Independent Death of HL-60 and Jurkat Cells Treated with the Inhibitor of NF-6B Parthenolide Cell Cycle. 2: 374-380. DOI: 10.4161/Cc.2.4.420  0.502
2003 Bino G, Darzynkiewicz Z, Degraef C, Mosselmans R, Fokan D, Galand P. Comparison of methods based on annexin-V binding, DNA content or TUNEL for evaluating cell death in HL-60 and adherent MCF-7 cells Cell Proliferation. 32: 25-37. DOI: 10.1046/J.1365-2184.1999.3210025.X  0.48
2002 Blagosklonny MV, Robey R, Sackett DL, Du L, Traganos F, Darzynkiewicz Z, Fojo T, Bates SE. Histone deacetylase inhibitors all induce p21 but differentially cause tubulin acetylation, mitotic arrest, and cytotoxicity Molecular Cancer Therapeutics. 1: 937-941. PMID 12481415  0.775
2002 Halicka DH, Pozarowski P, Ita M, Ardelt WJ, Mikulski SM, Shogen K, Darzynkiewicz Z. Enhancement of activation-induced apoptosis of lymphocytes by the cytotoxic ribonuclease onconase (Ranpirnase). International Journal of Oncology. 21: 1245-50. PMID 12429974 DOI: 10.3892/Ijo.21.6.1245  0.457
2002 Halicka HD, Smolewski P, Darzynkiewicz Z, Dai W, Traganos F. Arsenic trioxide arrests cells early in mitosis leading to apoptosis. Cell Cycle (Georgetown, Tex.). 1: 201-9. PMID 12429934  0.346
2002 Grabarek J, Du L, Johnson GL, Lee BW, Phelps DJ, Darzynkiewicz Z. Sequential activation of caspases and serine proteases (serpases) during apoptosis. Cell Cycle (Georgetown, Tex.). 1: 124-31. PMID 12429921 DOI: 10.4161/Cc.1.2.113  0.772
2002 Xie S, Wang Q, Luo L, Ruan Q, Liu T, Jhanwar-Uniyal M, Darzynkiewicz Z, Traganos F, Dai W. Proteasome-dependent downregulation of p21(Waf1/Cip1) induced by reactive oxygen species. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 22: 957-63. PMID 12396717 DOI: 10.1089/10799900260286669  0.317
2002 Hsieh T, Halicka D, Lu X, Kunicki J, Guo J, Darzynkiewicz Z, Wu J. Effects of resveratrol on the G(0)-G(1) transition and cell cycle progression of mitogenically stimulated human lymphocytes. Biochemical and Biophysical Research Communications. 297: 1311-7. PMID 12372431 DOI: 10.1016/S0006-291X(02)02384-7  0.433
2002 Grabarek J, Darzynkiewicz Z. In situ activation of caspases and serine proteases during apoptosis detected by affinity labeling their enzyme active centers with fluorochrome-tagged inhibitors. Experimental Hematology. 30: 982-9. PMID 12225789 DOI: 10.1016/S0301-472X(02)00886-X  0.423
2002 Grabarek J, Ardelt B, Du L, Darzynkiewicz Z. Activation of caspases and serine proteases during apoptosis induced by onconase (Ranpirnase). Experimental Cell Research. 278: 61-71. PMID 12126958 DOI: 10.1006/Excr.2002.5568  0.805
2002 Gorczyca W, Weisberger J, Liu Z, Tsang P, Hossein M, Wu CD, Dong H, Wong JY, Tugulea S, Dee S, Melamed MR, Darzynkiewicz Z. An approach to diagnosis of T-cell lymphoproliferative disorders by flow cytometry. Cytometry. 50: 177-90. PMID 12116341 DOI: 10.1002/Cyto.10003  0.314
2002 Darzynkiewicz Z, Bedner E, Smolewski P. In situ detection of DNA strand breaks in analysis of apoptosis by flow- and laser-scanning cytometry. Methods in Molecular Biology (Clifton, N.J.). 203: 69-77. PMID 12073455 DOI: 10.1385/1-59259-179-5:69  0.385
2002 Darzynkiewicz Z, Bedner E, Smolewski P, Lee BW, Johnson GL. Detection of caspases activation in situ by fluorochrome-labeled inhibitors of caspases (FLICA). Methods in Molecular Biology (Clifton, N.J.). 203: 289-99. PMID 12073450 DOI: 10.1385/1-59259-179-5:289  0.328
2002 Smolewski P, Grabarek J, Halicka HD, Darzynkiewicz Z. Assay of caspase activation in situ combined with probing plasma membrane integrity to detect three distinct stages of apoptosis. Journal of Immunological Methods. 265: 111-21. PMID 12072182 DOI: 10.1016/S0022-1759(02)00074-1  0.488
2002 Kapuscinski J, Ardelt B, Piosik J, Zdunek M, Darzynkiewicz Z. The modulation of the DNA-damaging effect of polycyclic aromatic agents by xanthines. Part I. Reduction of cytostatic effects of quinacrine mustard by caffeine. Biochemical Pharmacology. 63: 625-34. PMID 11992630 DOI: 10.1016/S0006-2952(01)00904-2  0.379
2002 Wang Q, Xie S, Chen J, Fukasawa K, Naik U, Traganos F, Darzynkiewicz Z, Jhanwar-Uniyal M, Dai W. Cell cycle arrest and apoptosis induced by human Polo-like kinase 3 is mediated through perturbation of microtubule integrity. Molecular and Cellular Biology. 22: 3450-9. PMID 11971976 DOI: 10.1128/Mcb.22.10.3450-3459.2002  0.435
2002 Smolewski P, Grabarek J, Lee BW, Johnson GL, Darzynkiewicz Z. Kinetics of HL-60 cell entry to apoptosis during treatment with TNF-alpha or camptothecin assayed by the stathmo-apoptosis method. Cytometry. 47: 143-9. PMID 11891718 DOI: 10.1002/Cyto.10062  0.484
2002 Grabarek J, Dragan M, Lee BW, Johnson GL, Darzynkiewicz Z. Activation of chymotrypsin-like serine protease(s) during apoptosis detected by affinity-labeling of the enzymatic center with fluoresceinated inhibitor. International Journal of Oncology. 20: 225-33. PMID 11788882  0.339
2002 Gorczyca W, Smolewski P, Grabarek J, Ardelt B, Ita M, Melamed MR, Darzynkiewicz Z. Morphometry of nucleoli and expression of nucleolin analyzed by laser scanning cytometry in mitogenically stimulated lymphocytes. Cytometry. 45: 206-13. PMID 11746089 DOI: 10.1002/1097-0320(20011101)45:3<206::Aid-Cyto1164>3.0.Co;2-9  0.356
2002 Halicka HD, Smolewski P, Darzynkiewicz Z, Dai W, Traganos F. Arsenic Trioxide Arrests Cells Early in Mitosis Leading to Apoptosis Cell Cycle. 1: 200-208. DOI: 10.4161/Cc.1.3.126  0.483
2002 Grabarek J, Dragan M, Lee BW, Johnson GL, Darzynkiewicz Z. Activation of chymotrypsin-like serine protease(s) during apoptosis detected by affinity-labeling of the enzymatic center with fluoresceinated inhibitor. International Journal of Oncology. 20: 225-233. DOI: 10.3892/Ijo.20.2.225  0.447
2002 Grabarek J, Darzynkiewicz Z. Versatility of analytical capabilities of laser scanning cytometry (LSC) Clinical and Applied Immunology Reviews. 2: 75-92. DOI: 10.1016/S1529-1049(01)00043-5  0.438
2002 Darzynkiewicz Z, Smolewski P, Bedner E. Use of flow and laser scanning cytometry to study mechanisms regulating cell cycle and controlling cell death Hematology/Oncology Clinics of North America. 16: 339-355. DOI: 10.1016/S0889-8588(02)00003-5  0.506
2001 Guibal FC, Moog-Lutz C, Smolewski P, Di Gioia Y, Darzynkiewicz Z, Lutz PG, Cayre YE. ASB-2 inhibits growth and promotes commitment in myeloid leukemia cells. The Journal of Biological Chemistry. 277: 218-24. PMID 11682484 DOI: 10.1074/Jbc.M108476200  0.391
2001 Smolewski P, Grabarek J, Kamentsky LA, Darzynkiewicz Z. Bivariate analysis of cellular DNA versus RNA content by laser scanning cytometry using the product of signal subtraction (differential fluorescence) as a separate parameter. Cytometry. 45: 73-8. PMID 11598949 DOI: 10.1002/1097-0320(20010901)45:1<73::Aid-Cyto1146>3.0.Co;2-A  0.344
2001 Chen S, Ruan Q, Bedner E, Deptala A, Wang X, Hsieh TC, Traganos F, Darzynkiewicz Z. Effects of the flavonoid baicalin and its metabolite baicalein on androgen receptor expression, cell cycle progression and apoptosis of prostate cancer cell lines. Cell Proliferation. 34: 293-304. PMID 11591177 DOI: 10.1046/J.0960-7722.2001.00213.X  0.386
2001 Du L, Smolewski P, Bedner E, Traganos F, Darzynkiewicz Z. Selective protection of mitogenically stimulated human lymphocytes but not leukemic cells from cytosine arabinoside-induced apoptosis by LY294002, a phosphoinositol-3 kinase inhibitor. International Journal of Oncology. 19: 811-9. PMID 11562760 DOI: 10.3892/Ijo.19.4.811  0.812
2001 Smolewski P, Grabarek J, Phelps DJ, Darzynkiewicz Z. Stathmo-apoptosis: arresting apoptosis by fluorochrome-labeled inhibitor of caspases. International Journal of Oncology. 19: 657-63. PMID 11562738 DOI: 10.3892/Ijo.19.4.657  0.487
2001 Smolewski P, Bedner E, Gorczyca W, Darzynkiewicz Z. "Liquidless" cell staining by dye diffusion from gels and analysis by laser scanning cytometry: potential application at microgravity conditions in space. Cytometry. 44: 355-60. PMID 11500852 DOI: 10.1002/1097-0320(20010801)44:4<355::Aid-Cyto1127>3.0.Co;2-W  0.307
2001 Leri A, Barlucchi L, Limana F, Deptala A, Darzynkiewicz Z, Hintze TH, Kajstura J, Nadal-Ginard B, Anversa P. Telomerase expression and activity are coupled with myocyte proliferation and preservation of telomeric length in the failing heart. Proceedings of the National Academy of Sciences of the United States of America. 98: 8626-31. PMID 11447262 DOI: 10.1073/Pnas.151013298  0.335
2001 Darzynkiewicz Z, Li X, Bedner E. Use of flow and laser-scanning cytometry in analysis of cell death. Methods in Cell Biology. 66: 69-109. PMID 11396020 DOI: 10.1016/S0091-679X(01)66005-9  0.416
2001 Dobrucki J, Darzynkiewicz Z. Chromatin condensation and sensitivity of DNA in situ to denaturation during cell cycle and apoptosis--a confocal microscopy study. Micron (Oxford, England : 1993). 32: 645-52. PMID 11334733 DOI: 10.1016/S0968-4328(00)00069-X  0.463
2001 Smolewski P, Bedner E, Du L, Hsieh TC, Wu JM, Phelps DJ, Darzynkiewicz Z. Detection of caspases activation by fluorochrome-labeled inhibitors: Multiparameter analysis by laser scanning cytometry. Cytometry. 44: 73-82. PMID 11309811 DOI: 10.1002/1097-0320(20010501)44:1<73::Aid-Cyto1084>3.0.Co;2-S  0.805
2001 Darzynkiewicz Z, Bedner E, Smolewski P. Flow cytometry in analysis of cell cycle and apoptosis. Seminars in Hematology. 38: 179-93. PMID 11309699 DOI: 10.1016/S0037-1963(01)90051-4  0.56
2001 Ardelt B, Kunicki J, Traganos F, Darzynkiewicz Z. Chlorophyllin protects cells from the cytostatic and cytotoxic effects of quinacrine mustard but not of nitrogen mustard. International Journal of Oncology. 18: 849-53. PMID 11251184 DOI: 10.3892/Ijo.18.4.849  0.434
2001 Bedner E, Du L, Traganos F, Darzynkiewicz Z. Caffeine dissociates complexes between DNA and intercalating dyes: application for bleaching fluorochrome-stained cells for their subsequent restaining and analysis by laser scanning cytometry. Cytometry. 43: 38-45. PMID 11122483 DOI: 10.1002/1097-0320(20010101)43:1<38::Aid-Cyto1017>3.0.Co;2-S  0.813
2001 Darzynkiewicz Z, Juan G, Traganos F. Assaying drug-induced apoptosis. Methods in Molecular Biology (Clifton, N.J.). 95: 241-54. PMID 11089236 DOI: 10.1385/1-59259-057-8:241  0.315
2001 Traganos F, Juan G, Darzynkiewicz Z. Cell-cycle analysis of drug-treated cells. Methods in Molecular Biology (Clifton, N.J.). 95: 229-40. PMID 11089235 DOI: 10.1385/1-59259-057-8:229  0.42
2001 Gorczyca W, Deptala A, Bedner E, Li X, Melamed MR, Darzynkiewicz Z. Analysis of human tumors by laser scanning cytometry. Methods in Cell Biology. 64: 421-43. PMID 11070850 DOI: 10.1016/S0091-679X(01)64024-X  0.339
2001 Darzynkiewicz Z, Bedner E, Traganos F. Difficulties and pitfalls in analysis of apoptosis. Methods in Cell Biology. 63: 527-46. PMID 11060857 DOI: 10.1016/S0091-679X(01)63028-0  0.383
2001 Juan G, Traganos F, Darzynkiewicz Z. Methods to identify mitotic cells by flow cytometry. Methods in Cell Biology. 63: 343-54. PMID 11060848 DOI: 10.1016/S0091-679X(01)63019-X  0.35
2001 Bedner E, Li X, Kunicki J, Darzynkiewicz Z. Translocation of Bax to mitochondria during apoptosis measured by laser scanning cytometry. Cytometry. 41: 83-8. PMID 11002262 DOI: 10.1002/1097-0320(20001001)41:2<83::Aid-Cyto1>3.0.Co;2-R  0.327
2001 Darzynkiewicz Z, Juan G, Srour EF. UNIT 7.3 Differential Staining of DNA and RNA Current Protocols in Immunology. DOI: 10.1002/0471142956.Cy0703S00  0.464
2000 Halicka HD, Murakami T, Papageorgio CN, Mittelman A, Mikulski SM, Shogen K, Darzynkiewicz Z. Induction of differentiation of leukaemic (HL-60) or prostate cancer (LNCaP, JCA-1) cells potentiates apoptosis triggered by onconase. Cell Proliferation. 33: 407-17. PMID 11101012 DOI: 10.1046/J.1365-2184.2000.00186.X  0.457
2000 Weisberger J, Wu CD, Liu Z, Wong JY, Melamed MR, Darzynkiewicz Z, Gorczyca W. Differential diagnosis of malignant lymphomas and related disorders by specific pattern of expression of immunophenotypic markers revealed by multiparameter flow cytometry (Review). International Journal of Oncology. 17: 1165-77. PMID 11078802 DOI: 10.3892/Ijo.17.6.1165  0.368
2000 Halicka HD, Bedner E, Darzynkiewicz Z. Segregation of RNA and separate packaging of DNA and RNA in apoptotic bodies during apoptosis. Experimental Cell Research. 260: 248-56. PMID 11035919 DOI: 10.1006/Excr.2000.5027  0.455
2000 Bedner E, Smolewski P, Amstad P, Darzynkiewicz Z. Activation of caspases measured in situ by binding of fluorochrome-labeled inhibitors of caspases (FLICA): correlation with DNA fragmentation. Experimental Cell Research. 259: 308-13. PMID 10942603 DOI: 10.1006/Excr.2000.4955  0.464
2000 Bedner E, Ruan Q, Chen S, Kamentsky LA, Darzynkiewicz Z. Multiparameter analysis of progeny of individual cells by laser scanning cytometry. Cytometry. 40: 271-9. PMID 10918278 DOI: 10.1002/1097-0320(20000801)40:4<271::Aid-Cyto3>3.0.Co;2-C  0.436
2000 Darzynkiewicz Z, Bedner E. Analysis of apoptotic cells by flow and laser scanning cytometry. Methods in Enzymology. 322: 18-39. PMID 10914002 DOI: 10.1016/S0076-6879(00)22005-3  0.517
2000 Li X, Du L, Darzynkiewicz Z. During apoptosis of HL-60 and U-937 cells caspases are activated independently of dissipation of mitochondrial electrochemical potential. Experimental Cell Research. 257: 290-7. PMID 10837143 DOI: 10.1006/Excr.2000.4901  0.801
2000 Lin CW, Darzynkiewicz Z, Li X, Traganos F, Bedner E, Tse-Dinh YC. Differential expression of human topoisomerase IIIα during the cell cycle progression in HL-60 leukemia cells and human peripheral blood lymphocytes Experimental Cell Research. 256: 225-236. PMID 10739669 DOI: 10.1006/Excr.1999.4778  0.463
2000 Kajstura J, Pertoldi B, Leri A, Beltrami CA, Deptala A, Darzynkiewicz Z, Anversa P. Telomere shortening is an in vivo marker of myocyte replication and aging. The American Journal of Pathology. 156: 813-9. PMID 10702397 DOI: 10.1016/S0002-9440(10)64949-8  0.351
2000 Li X, Darzynkiewicz Z. Cleavage of Poly(ADP-ribose) polymerase measured in situ in individual cells: relationship to DNA fragmentation and cell cycle position during apoptosis. Experimental Cell Research. 255: 125-32. PMID 10666341 DOI: 10.1006/Excr.1999.4796  0.516
1999 Deptala A, Li X, Bedner E, Cheng W, Traganos F, Darzynkiewicz Z. Differences in induction of p53, p21WAF1 and apoptosis in relation to cell cycle phase of MCF-7 cells treated with camptothecin. International Journal of Oncology. 15: 861-71. PMID 10536167 DOI: 10.3892/Ijo.15.5.861  0.513
1999 Li X, Patel R, Melamed MR, Darzynkiewicz Z. The cell cycle effects and induction of apoptosis by 5-bromouridine in cultures of human leukaemic MOLT-4 and HL-60 cell lines and mitogen-stimulated normal lymphocytes. Cell Proliferation. 27: 307-19. PMID 10465019 DOI: 10.1111/J.1365-2184.1994.Tb01428.X  0.513
1999 Darzynkiewicz Z, Li X, Bedner E. Detection of DNA strand breakage in the analysis of apoptosis and cell proliferation by flow and laser scanning cytometry. Methods in Molecular Biology (Clifton, N.J.). 113: 607-19. PMID 10443456 DOI: 10.1385/1-59259-675-4:607  0.455
1999 Darzynkiewicz Z, Juan G. Selective extraction of fragmented DNA from apoptotic cells for analysis by gel electrophoresis and identification of apoptotic cells by flow cytometry. Methods in Molecular Biology (Clifton, N.J.). 113: 599-605. PMID 10443455 DOI: 10.1385/1-59259-675-4:599  0.471
1999 Hsieh TC, Burfeind P, Laud K, Backer JM, Traganos F, Darzynkiewicz Z, Wu JM. Cell cycle effects and control of gene expression by resveratrol in human breast carcinoma cell lines with different metastatic potentials International Journal of Oncology. 15: 245-252. PMID 10402233 DOI: 10.3892/Ijo.15.2.245  0.409
1999 Li X, Darzynkiewicz Z. The Schrödinger's cat quandary in cell biology: integration of live cell functional assays with measurements of fixed cells in analysis of apoptosis. Experimental Cell Research. 249: 404-12. PMID 10366440 DOI: 10.1006/Excr.1999.4525  0.554
1999 Bedner E, Halicka HD, Cheng W, Salomon T, Deptala A, Gorczyca W, Melamed MR, Darzynkiewicz Z. High affinity binding of fluorescein isothiocyanate to eosinophils detected by laser scanning cytometry: a potential source of error in analysis of blood samples utilizing fluorescein-conjugated reagents in flow cytometry. Cytometry. 36: 77-82. PMID 10331630 DOI: 10.1002/(Sici)1097-0320(19990501)36:1<77::Aid-Cyto10>3.3.Co;2-6  0.386
1999 Darzynkiewicz Z, Bedner E, Li X, Gorczyca W, Melamed MR. Laser-scanning cytometry: A new instrumentation with many applications. Experimental Cell Research. 249: 1-12. PMID 10328948 DOI: 10.1006/Excr.1999.4477  0.483
1999 Bedner E, Li X, Gorczyca W, Melamed MR, Darzynkiewicz Z. Analysis of apoptosis by laser scanning cytometry. Cytometry. 35: 181-95. PMID 10082299 DOI: 10.1002/(Sici)1097-0320(19990301)35:3<181::Aid-Cyto1>3.0.Co;2-5  0.489
1999 Darzynkiewicz Z. The butler did it: search for killer(s) of Kaposi's sarcoma cells in preparations of human chorionic gonadotropin. Journal of the National Cancer Institute. 91: 104-6. PMID 9923845 DOI: 10.1093/Jnci/91.2.104  0.393
1999 Juan G, Traganos F, Darzynkiewicz Z. Histone H3 phosphorylation in human monocytes and during HL-60 cell differentiation. Experimental Cell Research. 246: 212-20. PMID 9882530 DOI: 10.1006/Excr.1998.4283  0.362
1999 Deptala A, Bedner E, Gorczyca W, Darzynkiewicz Z. Activation of nuclear factor kappa B (NF-kappaB) assayed by laser scanning cytometry (LSC). Cytometry. 33: 376-82. PMID 9822350 DOI: 10.1002/(Sici)1097-0320(19981101)33:3<376::Aid-Cyto13>3.0.Co;2-Q  0.348
1999 Tan L, Kowalska MA, Romo GM, Lopez JA, Darzynkiewicz Z, Niewiarowski S. Identification and Characterization of Endothelial Glycoprotein Ib Using Viper Venom Proteins Modulating Cell Adhesion Blood. 93: 2605-2616. DOI: 10.1182/Blood.V93.8.2605.408K18_2605_2616  0.339
1998 Feldman EJ, Seiter K, Chiao JW, Halicka HD, Traganos F, Fatora SR, McMichael J, Baskind P, Goff H, Beer M, Ahmed T, Darzynkiewicz Z. In vitro effects and clinical evaluation of a human chorionic gonadotrophin preparation in acute leukemia. Leukemia. 12: 1749-55. PMID 9823950 DOI: 10.1038/Sj.Leu.2401196  0.427
1998 Juan G, Li X, Darzynkiewicz Z. Phosphorylation of retinoblastoma protein assayed in individual HL-60 cells during their proliferation and differentiation. Experimental Cell Research. 244: 83-92. PMID 9770352 DOI: 10.1006/Excr.1998.4165  0.468
1998 Darzynkiewicz Z, Traganos F. Measurement of apoptosis. Advances in Biochemical Engineering/Biotechnology. 62: 33-73. PMID 9755640 DOI: 10.1007/Bfb0102305  0.478
1998 Mikulski SM, Viera A, Deptala A, Darzynkiewicz Z. Enhanced in vitro cytotoxicity and cytostasis of the combination of onconase with a proteasome inhibitor. International Journal of Oncology. 13: 633-44. PMID 9735389 DOI: 10.3892/Ijo.13.4.633  0.424
1998 Bedner E, Burfeind P, Hsieh TC, Wu JM, Aguero-Rosenfeld ME, Melamed MR, Horowitz HW, Wormser GP, Darzynkiewicz Z. Cell cycle effects and induction of apoptosis caused by infection of HL-60 cells with human granulocytic ehrlichiosis pathogen measured by flow and laser scanning cytometry. Cytometry. 33: 47-55. PMID 9725558 DOI: 10.1002/(Sici)1097-0320(19980901)33:1<47::Aid-Cyto6>3.0.Co;2-8  0.422
1998 Bedner E, Melamed MR, Darzynkiewicz Z. Enzyme kinetic reactions and fluorochrome uptake rates measured in individual cells by laser scanning cytometry. Cytometry. 33: 1-9. PMID 9725553 DOI: 10.1002/(Sici)1097-0320(19980901)33:1<1::Aid-Cyto1>3.0.Co;2-P  0.4
1998 Juan G, Ardelt B, Li X, Mikulski SM, Shogen K, Ardelt W, Mittelman A, Darzynkiewicz Z. G1 arrest of U937 cells by onconase is associated with suppression of cyclin D3 expression, induction of p16INK4A, p21WAF1/CIP1 and p27KIP and decreased pRb phosphorylation. Leukemia. 12: 1241-8. PMID 9697879 DOI: 10.1038/Sj.Leu.2401100  0.442
1998 Gorczyca W, Melamed MR, Darzynkiewicz Z. Analysis of apoptosis by flow cytometry. Methods in Molecular Biology (Clifton, N.J.). 91: 217-38. PMID 9664496 DOI: 10.1385/0-89603-354-6:217  0.304
1998 Juan G, Darzynkiewicz Z. Detection of cyclins in individual cells by flow and laser scanning cytometry. Methods in Molecular Biology (Clifton, N.J.). 91: 67-75. PMID 9664482 DOI: 10.1385/0-89603-354-6:67  0.338
1998 Juan G, Traganos F, James WM, Ray JM, Roberge M, Sauve DM, Anderson H, Darzynkiewicz Z. Histone H3 phosphorylation and expression of cyclins A and B1 measured in individual cells during their progression through G2 and mitosis Cytometry. 32: 71-77. PMID 9627219 DOI: 10.1002/(Sici)1097-0320(19980601)32:2<71::Aid-Cyto1>3.0.Co;2-H  0.403
1998 Deptala A, Halicka HD, Ardelt B, Ardelt W, Mikulski SM, Shogen K, Darzynkiewicz Z. Potentiation of tumor necrosis factor induced apoptosis by onconase. International Journal of Oncology. 13: 11-6. PMID 9625797 DOI: 10.3892/Ijo.13.1.11  0.343
1998 Juan G, Gruenwald S, Darzynkiewicz Z. Phosphorylation of retinoblastoma susceptibility gene protein assayed in individual lymphocytes during their mitogenic stimulation. Experimental Cell Research. 239: 104-10. PMID 9511729 DOI: 10.1006/Excr.1997.3885  0.438
1998 Juan G, Darzynkiewicz Z. Phosphorylation of retinoblastoma protein (pRb) assayed in individual cells by multilaser flow cytometry Clinical Immunology Newsletter. 18: 89-94. DOI: 10.1016/S0197-1859(00)89182-7  0.361
1997 Bedner E, Burfeind P, Gorczyca W, Melamed MR, Darzynkiewicz Z. Laser scanning cytometry distinguishes lymphocytes, monocytes, and granulocytes by differences in their chromatin structure. Cytometry. 29: 191-6. PMID 9389435 DOI: 10.1002/(Sici)1097-0320(19971101)29:3<191::Aid-Cyto1>3.0.Co;2-F  0.409
1997 Sailer BL, Valdez JG, Steinkamp JA, Darzynkiewicz Z, Crissman HA. Monitoring uptake of ellipticine and its fluorescence lifetime in relation to the cell cycle phase by flow cytometry. Experimental Cell Research. 236: 259-67. PMID 9344606 DOI: 10.1006/Excr.1997.3717  0.472
1997 Haider SR, Juan G, Traganos F, Darzynkiewicz Z. Immunoseparation and immunodetection of nucleic acids labeled with halogenated nucleotides. Experimental Cell Research. 234: 498-506. PMID 9260920 DOI: 10.1006/Excr.1997.3644  0.403
1997 Vibhakar R, Juan G, Traganos F, Darzynkiewicz Z, Finger LR. Activation-induced expression of human programmed death-1 gene in T-lymphocytes. Experimental Cell Research. 232: 25-8. PMID 9141617 DOI: 10.1006/Excr.1997.3493  0.365
1997 Gorczyca W, Melamed MR, Darzynkiewicz Z. Laser scanning cytometer (LSC) analysis of fraction of labelled mitoses (FLM). Cell Proliferation. 29: 539-47. PMID 9051117 DOI: 10.1111/J.1365-2184.1996.Tb00969.X  0.507
1997 Darzynkiewicz Z, Juan G, Li X, Gorczyca W, Murakami T, Traganos F. Cytometry in cell necrobiology: analysis of apoptosis and accidental cell death (necrosis). Cytometry. 27: 1-20. PMID 9000580 DOI: 10.1002/(Sici)1097-0320(19970101)27:1<1::Aid-Cyto2>3.0.Co;2-L  0.485
1997 Traganos F, Seiter K, Feldman E, Halicka HD, Darzynkiewicz Z. Induction of apoptosis by camptothecin and topotecan. Annals of the New York Academy of Sciences. 803: 101-10. PMID 8993504 DOI: 10.1111/J.1749-6632.1996.Tb26380.X  0.335
1997 Darzynkiewicz Z, Bruno S, Del Bino G, Traganos F. The cell cycle effects of camptothecin. Annals of the New York Academy of Sciences. 803: 93-100. PMID 8993503 DOI: 10.1111/J.1749-6632.1996.Tb26379.X  0.434
1997 Darzynkiewicz Z, Gong J, Juan G, Ardelt B, Traganos F. Cytometry of cyclin proteins. Cytometry. 25: 1-13. PMID 8875049 DOI: 10.1002/(Sici)1097-0320(19960901)25:1<1::Aid-Cyto1>3.0.Co;2-N  0.485
1996 Juan G, Pan W, Darzynkiewicz Z. DNA segments sensitive to single-strand-specific nucleases are present in chromatin of mitotic cells. Experimental Cell Research. 227: 197-202. PMID 8831556 DOI: 10.1006/Excr.1996.0267  0.497
1996 Juan G, Gong J, Traganos F, Darzynkiewicz Z. Unscheduled expression of cyclins D1 and D3 in human tumour cell lines. Cell Proliferation. 29: 259-66. PMID 8782488 DOI: 10.1046/J.1365-2184.1996.01000.X  0.389
1996 Hara S, Halicka HD, Bruno S, Gong J, Traganos F, Darzynkiewicz Z. Effect of protease inhibitors on early events of apoptosis. Experimental Cell Research. 223: 372-84. PMID 8601414 DOI: 10.1006/Excr.1996.0092  0.45
1996 Li X, Darzynkiewicz Z. Labelling DNA strand breaks with BrdUTP. Detection of apoptosis and cell proliferation. Cell Proliferation. 28: 571-9. PMID 8555370 DOI: 10.1111/J.1365-2184.1995.Tb00045.X  0.448
1996 Li X, Melamed MR, Darzynkiewicz Z. Detection of apoptosis and DNA replication by differential labeling of DNA strand breaks with fluorochromes of different color. Experimental Cell Research. 222: 28-37. PMID 8549670 DOI: 10.1006/Excr.1996.0004  0.511
1996 Skorski T, Nieborowska-Skorska M, Campbell K, Iozzo RV, Zon G, Darzynkiewicz Z, Calabretta B. Leukemia treatment in severe combined immunodeficiency mice by antisense oligodeoxynucleotides targeting cooperating oncogenes. The Journal of Experimental Medicine. 182: 1645-53. PMID 7500009 DOI: 10.1084/Jem.182.6.1645  0.346
1995 Li X, James WM, Traganos F, Darzynkiewicz Z. Application of biotin, digoxigenin or fluorescein conjugated deoxynucleotides to label DNA Strand breaks for analysis of cell proliferation and apoptosis using flow cytometry Biotechnic and Histochemistry. 70: 234-242. PMID 8580207 DOI: 10.3109/10520299509108200  0.512
1995 Darzynkiewicz Z, Gong J, Traganos F. Analysis of DNA content and cyclin protein expression in studies of DNA ploidy, growth fraction, lymphocyte stimulation, and the cell cycle. Methods in Cell Biology. 41: 421-35. PMID 7861973 DOI: 10.1016/S0091-679X(08)61732-X  0.437
1995 Darzynkiewicz Z, Li X, Gong J. Assays of cell viability: discrimination of cells dying by apoptosis. Methods in Cell Biology. 41: 15-38. PMID 7861963 DOI: 10.1016/S0091-679X(08)61707-0  0.522
1995 Darzynkiewicz Z. Apoptosis in antitumor strategies: modulation of cell cycle or differentiation. Journal of Cellular Biochemistry. 58: 151-9. PMID 7673323 DOI: 10.1002/Jcb.240580204  0.504
1995 Gong J, Traganos F, Darzynkiewicz Z. Discrimination of G2 and mitotic cells by flow cytometry based on different expression of cyclins A and B1. Experimental Cell Research. 220: 226-31. PMID 7664839 DOI: 10.1006/Excr.1995.1310  0.489
1995 Li X, Traganos F, Melamed MR, Darzynkiewicz Z. Single-step procedure for labeling DNA strand breaks with fluorescein- or BODIPY-conjugated deoxynucleotides: detection of apoptosis and bromodeoxyuridine incorporation. Cytometry. 20: 172-80. PMID 7664627 DOI: 10.1002/Cyto.990200210  0.496
1995 Venturelli D, Martinez R, Melotti P, Casella I, Peschle C, Cucco C, Spampinato G, Darzynkiewicz Z, Calabretta B. Overexpression of DR-nm23, a protein encoded by a member of the nm23 gene family, inhibits granulocyte differentiation and induces apoptosis in 32Dc13 myeloid cells. Proceedings of the National Academy of Sciences of the United States of America. 92: 7435-9. PMID 7638209 DOI: 10.1073/Pnas.92.16.7435  0.341
1995 Gong J, Traganos F, Darzynkiewicz Z. Threshold expression of cyclin E but not D type cyclins characterizes normal and tumour cells entering S phase. Cell Proliferation. 28: 337-46. PMID 7626688 DOI: 10.1111/J.1365-2184.1995.Tb00075.X  0.445
1995 Ronai Z, Tillotson JK, Traganos F, Darzynkiewicz Z, Conaway CC, Upadhyaya P, el-Bayoumy K. Effects of organic and inorganic selenium compounds on rat mammary tumor cells. International Journal of Cancer. 63: 428-34. PMID 7591244 DOI: 10.1002/Ijc.2910630322  0.454
1995 Darzynkiewicz Z. Acid-induced denaturation of DNA in situ as a probe of chromatin structure. Methods in Cell Biology. 41: 527-41. PMID 7532268 DOI: 10.1016/S0091-679X(08)61738-0  0.454
1995 Darzynkiewicz Z. Simultaneous analysis of cellular RNA and DNA content. Methods in Cell Biology. 41: 401-20. PMID 7532267 DOI: 10.1016/S0091-679X(08)61731-8  0.374
1995 Traganos F, Darzynkiewicz Z. Lysosomal proton pump activity: supravital cell staining with acridine orange differentiates leukocyte subpopulations. Methods in Cell Biology. 41: 185-94. PMID 7532261 DOI: 10.1016/S0091-679X(08)61717-3  0.304
1994 Black RS, DeGiorgio LA, Sheu KFR, Darzynkiewicz Z, Duffy JT, Blass JP. Expression of neuronal proteins in cells from normal adult rat brain propagated in serial culture Journal of Neurochemistry. 62: 2132-2140. PMID 8189221 DOI: 10.1046/J.1471-4159.1994.62062132.X  0.307
1994 Hotz MA, Gong J, Traganos F, Darzynkiewicz Z. Flow cytometric detection of apoptosis: comparison of the assays of in situ DNA degradation and chromatin changes. Cytometry. 15: 237-44. PMID 8187583 DOI: 10.1002/Cyto.990150309  0.515
1994 Gorczyca W, Tuziak T, Kram A, Melamed MR, Darzynkiewicz Z. Detection of apoptosis-associated DNA strand breaks in fine-needle aspiration biopsies by in situ end labeling of fragmented DNA. Cytometry. 15: 169-75. PMID 8168404 DOI: 10.1002/Cyto.990150211  0.47
1994 Traganos F, Gong J, Ardelt B, Darzynkiewicz Z. Effect of staurosporine on MOLT-4 cell progression through G2 and on cytokinesis. Journal of Cellular Physiology. 158: 535-44. PMID 8126077 DOI: 10.1002/Jcp.1041580320  0.511
1994 Li X, Gong J, Feldman E, Seiter K, Traganos F, Darzynkiewicz Z. Apoptotic cell death during treatment of leukemias. Leukemia & Lymphoma. 65-70. PMID 8075583 DOI: 10.3109/10428199409052678  0.496
1994 Gong J, Traganos F, Darzynkiewicz Z. A selective procedure for DNA extraction from apoptotic cells applicable for gel electrophoresis and flow cytometry. Analytical Biochemistry. 218: 314-9. PMID 8074286 DOI: 10.1006/Abio.1994.1184  0.472
1994 Wang ZQ, Dudhane A, Orlikowsky T, Clarke K, Li X, Darzynkiewicz Z, Hoffmann MK. CD4 engagement induces Fas antigen-dependent apoptosis of T cells in vivo. European Journal of Immunology. 24: 1549-52. PMID 7517874 DOI: 10.1002/Eji.1830240714  0.333
1994 Gong J, Li X, Traganos F, Darzynkiewicz Z. Expression of G1and G2cyclins measured in individual cells by multiparameter flow cytometry: a new tool in the analysis of the cell cycle Cell Proliferation. 27: 357-371. DOI: 10.1111/J.1365-2184.1994.Tb01469.X  0.474
1993 Darzynkiewicz Z, Gorczyca W, Lassota P, Traganos F. Altered sensitivity of DNA in situ to denaturation in apoptotic cells. Annals of the New York Academy of Sciences. 677: 334-40. PMID 8494219 DOI: 10.1111/J.1749-6632.1993.Tb38788.X  0.493
1993 Capasso JM, Bruno S, Li P, Zhang X, Darzynkiewicz Z, Anversa P. Myocyte DNA synthesis with aging: correlation with ventricular loading in rats. Journal of Cellular Physiology. 155: 635-48. PMID 8491794 DOI: 10.1002/Jcp.1041550320  0.302
1993 Gorczyca W, Traganos F, Jesionowska H, Darzynkiewicz Z. Presence of DNA strand breaks and increased sensitivity of DNA in situ to denaturation in abnormal human sperm cells: analogy to apoptosis of somatic cells. Experimental Cell Research. 207: 202-5. PMID 8391465 DOI: 10.1006/Excr.1993.1182  0.509
1993 Gorczyca W, Melamed MR, Darzynkiewicz Z. Apoptosis of S-phase HL-60 cells induced by DNA topoisomerase inhibitors: detection of DNA strand breaks by flow cytometry using the in situ nick translation assay. Toxicology Letters. 67: 249-58. PMID 8383887 DOI: 10.1016/0378-4274(93)90060-B  0.524
1993 Gong J, Li X, Darzynkiewicz Z. Different patterns of apoptosis of HL-60 cells induced by cycloheximide and camptothecin. Journal of Cellular Physiology. 157: 263-70. PMID 8227159 DOI: 10.1002/Jcp.1041570208  0.494
1993 Darzynkiewicz Z, Bruno S, Del Bino G, Gorczyca W, Hotz MA, Lassota P, Traganos F. Features of apoptotic cells measured by flow cytometry. Cytometry. 13: 795-808. PMID 1333943 DOI: 10.1002/Cyto.990130802  0.563
1993 Del Bino G, Bruno S, Yi PN, Darzynkiewicz Z. Apoptotic cell death triggered by camptothecin or teniposide. The cell cycle specificity and effects of ionizing radiation. Cell Proliferation. 25: 537-48. PMID 1333822 DOI: 10.1111/J.1365-2184.1992.Tb01458.X  0.531
1992 Bruno S, Darzynkiewicz Z. Cell cycle dependent expression and stability of the nuclear protein detected by Ki-67 antibody in HL-60 cells Cell Proliferation. 25: 31-40. PMID 1540682 DOI: 10.1111/J.1365-2184.1992.Tb01435.X  0.476
1992 Mikulski SM, Viera A, Darzynkiewicz Z, Shogen K. Synergism between a novel amphibian oocyte ribonuclease and lovastatin in inducing cytostatic and cytotoxic effects in human lung and pancreatic carcinoma cell lines. British Journal of Cancer. 66: 304-10. PMID 1503903 DOI: 10.1038/Bjc.1992.261  0.405
1992 Capasso JM, Bruno S, Cheng W, Li P, Rodgers R, Darzynkiewicz Z, Anversa P. Ventricular loading is coupled with DNA synthesis in adult cardiac myocytes after acute and chronic myocardial infarction in rats. Circulation Research. 71: 1379-89. PMID 1423934 DOI: 10.1161/01.Res.71.6.1379  0.305
1992 Black RS, Bouvier MM, Sheu KF, Darzynkiewicz Z, Blass JP. Presence of typical neuronal markers in serially cultured cells from adult human brain. Journal of the Neurological Sciences. 111: 104-12. PMID 1402991 DOI: 10.1016/0022-510X(92)90118-5  0.327
1992 Bruno S, Gorczyca W, Darzynkiewicz Z. Effect of ionic strength in immunocytochemical detection of the proliferation associated nuclear antigens p120, PCNA, and the protein reacting with Ki-67 antibody Cytometry. 13: 496-501. PMID 1353016 DOI: 10.1002/Cyto.990130508  0.376
1992 Bruno S, Giaretti W, Darzynkiewicz Z. Effect of camptothecin on mitogenic stimulation of human lymphocytes: Involvement of DNA topoisomerase I in cell transition from G0 to G1 phase of the cell cycle and in DNA replication Journal of Cellular Physiology. 151: 478-486. PMID 1338332 DOI: 10.1002/Jcp.1041510306  0.432
1992 Myc A, Traganos F, Lara J, Melamed MR, Darzynkiewicz Z. DNA stainability in aneuploid breast tumors: comparison of four DNA fluorochromes differing in binding properties. Cytometry. 13: 389-94. PMID 1326430 DOI: 10.1002/Cyto.990130409  0.406
1992 Hotz MA, Traganos F, Darzynkiewicz Z. Changes in nuclear chromatin related to apoptosis or necrosis induced by the DNA topoisomerase II inhibitor fostriecin in MOLT-4 and HL-60 cells are revealed by altered DNA sensitivity to denaturation. Experimental Cell Research. 201: 184-91. PMID 1319346 DOI: 10.1016/0014-4827(92)90362-C  0.532
1992 Rivas C, Wisniewski D, Strife A, Perez A, Lambek C, Bruno S, Darzynkiewicz Z, Clarkson B. Constitutive expression of p53 protein in enriched normal human marrow blast cell populations [see comments] Blood. 79: 1982-1986. DOI: 10.1182/Blood.V79.8.1982.Bloodjournal7981982  0.347
1992 Darzynkiewicz Z. Cell apoptosis and necrosis studied by flow cytometry Biology of the Cell. 76: 247-247. DOI: 10.1016/0248-4900(92)90325-U  0.403
1991 Darzynkiewicz Z. Acid-induced denaturation of DNA in situ as a probe of chromatin structure. Methods in Cell Biology. 33: 337-52. PMID 2084473 DOI: 10.1016/S0091-679X(08)60537-3  0.375
1991 Traganos F, Kaminska-Eddy B, Darzynkiewicz Z. Caffeine reverses the cytotoxic and cell kinetic effects of Novantrone (mitoxantrone). Cell Proliferation. 24: 305-19. PMID 2039806 DOI: 10.1111/J.1365-2184.1991.Tb01159.X  0.493
1991 Lassota P, Melamed MR, Darzynkiewicz Z. Release of specific proteins from nuclei of HL-60 and MOLT-4 cells by antitumor drugs having affinity to nucleic acids. Biochemical Pharmacology. 41: 1055-65. PMID 2009074 DOI: 10.1016/0006-2952(91)90214-P  0.378
1991 Del Bino G, Lassota P, Darzynkiewicz Z. The S-phase cytotoxicity of camptothecin. Experimental Cell Research. 193: 27-35. PMID 1995300 DOI: 10.1016/0014-4827(91)90534-2  0.502
1991 Myc A, DeAngelis P, Kimmel M, Melamed MR, Darzynkiewicz Z. Retention of the mitochondrial probe rhodamine 123 in normal lymphocytes and leukemic cells in relation to the cell cycle Experimental Cell Research. 192: 198-202. PMID 1984411 DOI: 10.1016/0014-4827(91)90176-U  0.404
1991 Bruno S, Crissman HA, Bauer KD, Darzynkiewicz Z. Changes in cell nuclei during S phase: progressive chromatin condensation and altered expression of the proliferation-associated nuclear proteins Ki-67, cyclin (PCNA), p105, and p34. Experimental Cell Research. 196: 99-106. PMID 1831764 DOI: 10.1016/0014-4827(91)90460-C  0.424
1991 Crissman HA, Darzynkiewicz Z, Steinkamp JA, Tobey RA. Simultaneous fluorescent labeling of DNA, RNA, and protein. Methods in Cell Biology. 33: 305-14. PMID 1707489 DOI: 10.1016/S0091-679X(08)60534-8  0.434
1991 Darzynkiewicz Z. Differential staining of DNA and RNA in intact cells and isolated cell nuclei with acridine orange. Methods in Cell Biology. 33: 285-98. PMID 1707487 DOI: 10.1016/S0091-679X(08)60532-4  0.367
1991 Jakóbisiak M, Bruno S, Skierski JS, Darzynkiewicz Z. Cell cycle-specific effects of lovastatin. Proceedings of the National Academy of Sciences of the United States of America. 88: 3628-32. PMID 1673788 DOI: 10.1073/Pnas.88.9.3628  0.492
1991 Del Bino G, Skierski JS, Darzynkiewicz Z. The concentration-dependent diversity of effects of DNA topoisomerase I and II inhibitors on the cell cycle of HL-60 cells. Experimental Cell Research. 195: 485-91. PMID 1649059 DOI: 10.1016/0014-4827(91)90400-O  0.48
1991 Darzynkiewicz Z. Flow cytometric methods for RNA content analysis Methods. 2: 200-206. DOI: 10.1016/S1046-2023(05)80062-3  0.369
1990 Bories D, Raynal MC, Solomon DH, Darzynkiewicz Z, Cayre YE. Down-regulation of a serine protease, myeloblastin, causes growth arrest and differentiation of promyelocytic leukemia cells. Cell. 59: 959-68. PMID 2598267 DOI: 10.1016/0092-8674(89)90752-6  0.449
1990 Evenson D, Darzynkiewicz Z. Acridine orange-induced precipitation of mouse testicular sperm cell DNA reveals new patterns of chromatin structure. Experimental Cell Research. 187: 328-34. PMID 2318269 DOI: 10.1016/0014-4827(90)90100-O  0.384
1990 Kunicka JE, Myc A, Melamed MR, Darzynkiewicz Z. Caffeine increases sensitivity of DNA to denaturation in chromatin of L1210 cells. Cell and Tissue Kinetics. 23: 31-9. PMID 1689215 DOI: 10.1111/J.1365-2184.1990.Tb01107.X  0.522
1989 Darzynkiewicz Z, Carter SP, Kapuscinski J, Watanabe KA. Effect of derivatives of chrysophanol, a new type of potential antitumor agents of anthraquinone family, on growth and cell cycle of L1210 leukemic cells Cancer Letters. 46: 181-187. PMID 2766258 DOI: 10.1016/0304-3835(89)90128-6  0.453
1989 Koyama M, Takahashi K, Chou TC, Darzynkiewicz Z, Kapuscinski J, Kelly TR, Watanabe KA. Intercalating agents with covalent bond forming capability. A novel type of potential anticancer agents. 2. Derivatives of chrysophanol and emodin. Journal of Medicinal Chemistry. 32: 1594-9. PMID 2738893 DOI: 10.1021/Jm00127A032  0.406
1989 Staiano-Coico L, Darzynkiewicz Z, McMahon CK. Cultured human keratinocytes: discrimination of different cell cycle compartments based upon measurement of nuclear RNA or total cellular RNA content. Cell and Tissue Kinetics. 22: 235-43. PMID 2478288 DOI: 10.1111/J.1365-2184.1989.Tb00209.X  0.364
1989 Darzynkiewicz Z, Carter SP. Thermal stability of nucleosomes studied in situ by flow cytometry: Effect of ionic strength and n-butyrate Experimental Cell Research. 180: 551-556. PMID 2464501 DOI: 10.1016/0014-4827(89)90082-7  0.376
1988 Darzynkiewicz Z, Carter SP, Mikulski SM, Ardelt WJ, Shogen K. Cytostatic and cytotoxic effects of Pannon (P-30 Protein), a novel anticancer agent. Cell and Tissue Kinetics. 21: 169-82. PMID 3224365 DOI: 10.1111/J.1365-2184.1988.Tb00855.X  0.481
1988 Darzynkiewicz Z, Tudor EM, Hopper JL, Hannah MC. An autoradiographic study of the developing parietal cell population in neonatal pigs. Cell Proliferation. 21: 3-14. PMID 3191523 DOI: 10.1111/J.1365-2184.1988.Tb00766.X  0.412
1988 Kapuscinski J, Traganos F, Darzynkiewicz Z. Interactions of antitumor drug ditercalinium with nucleic acids in solutions and in situ. Cancer Letters. 42: 185-91. PMID 3191470 DOI: 10.1016/0304-3835(88)90303-5  0.303
1988 Darzynkiewicz Z, Kapuscinski J. Condensation of DNA in situ in metaphase chromosomes induced by intercalating ligands and its relationship to chromosome banding. Cytometry. 9: 7-18. PMID 3044712 DOI: 10.1002/Cyto.990090103  0.338
1988 Traganos F, Crissman HA, Darzynkiewicz Z. Staining with pyronin Y detects changes in conformation of RNA during mitosis and hyperthermia of CHO cells. Experimental Cell Research. 179: 535-44. PMID 2461311 DOI: 10.1016/0014-4827(88)90291-1  0.368
1988 Walle AJ, Wong GY, Suthanthiran M, Rubin AL, Stenzel KH, Darzynkiewicz Z. Altered nucleic acid contents of mononuclear cells in blood of renal allograft recipients. Cytometry. 9: 177-82. PMID 2452058 DOI: 10.1002/Cyto.990090213  0.45
1988 Traganos F, Kimmel M, Bueti C, Darzynkiewicz Z. Effects of inhibition of RNA or protein synthesis on CHO cell cycle progression. Journal of Cellular Physiology. 133: 277-87. PMID 2445763 DOI: 10.1002/Jcp.1041330211  0.425
1987 Darzynkiewicz Z, Traganos F, Carter SP, Higgins PJ. In situ factors affecting stability of the DNA helix in interphase nuclei and metaphase chromosomes Experimental Cell Research. 172: 168-179. PMID 3653252 DOI: 10.1016/0014-4827(87)90103-0  0.46
1987 Kapuscinski J, Darzynkiewicz Z. Interactions of pyronin Y(G) with nucleic acids. Cytometry. 8: 129-37. PMID 3582061 DOI: 10.1002/Cyto.990080205  0.309
1987 Darzynkiewicz Z, Carter SP, Old LJ. Effect of recombinant tumor necrosis factor on HL-60 cells: Cell-cycle specificity and synergism with actinomycin D Journal of Cellular Physiology. 130: 328-335. PMID 3470296 DOI: 10.1002/Jcp.1041300304  0.444
1987 Cayre Y, Raynal MC, Darzynkiewicz Z, Dorner MH. Model for intermediate steps in monocytic differentiation: c-myc, c-fms, and ferritin as markers Proceedings of the National Academy of Sciences of the United States of America. 84: 7619-7623. PMID 3313399 DOI: 10.1073/Pnas.84.21.7619  0.338
1987 Kapuscinski J, Darzynkiewicz Z. Interactions of acridine orange with double stranded nucleic acids. Spectral and affinity studies. Journal of Biomolecular Structure & Dynamics. 5: 127-43. PMID 3271462 DOI: 10.1080/07391102.1987.10506381  0.328
1987 Tobey RA, Crissman HA, Wilder ME, Traganos F, Darzynkiewicz Z. Sensitivity to X-irradiation in relation to cell size of CHO cells synchronized in early G1. Cell and Tissue Kinetics. 20: 363-6. PMID 2446765 DOI: 10.1111/J.1365-2184.1987.Tb01318.X  0.384
1987 Darzynkiewicz Z, Kapuscinski J, Traganos F, Crissman HA. Application of pyronin Y(G) in cytochemistry of nucleic acids. Cytometry. 8: 138-45. PMID 2438101 DOI: 10.1002/Cyto.990080206  0.382
1987 Darzynkiewicz Z, Staiano-Coico L, Kunicka JE, DeLeo AB, Old LJ. p53 content in relation to cell growth and proliferation in murine L1210 leukemia and normal lymphocytes. Leukemia Research. 10: 1383-9. PMID 2432361 DOI: 10.1016/0145-2126(86)90004-4  0.431
1986 Melamed MR, Enker WE, Banner P, Janov AJ, Kessler G, Darzynkiewicz Z. Flow cytometry of colorectal carcinoma with three-year follow-up. Diseases of the Colon and Rectum. 29: 184-6. PMID 3943434 DOI: 10.1007/Bf02555020  0.305
1986 Kapuscinski J, Darzynkiewicz Z. Relationship between the pharmacological activity of antitumor drugs Ametantrone and mitoxantrone (Novatrone) and their ability to condense nucleic acids. Proceedings of the National Academy of Sciences of the United States of America. 83: 6302-6. PMID 3462696 DOI: 10.1073/Pnas.83.17.6302  0.319
1986 Darzynkiewicz Z, Traganos F, Staiano-Coico L. Cell and nuclear growth during G1: kinetic and clinical implications. Annals of the New York Academy of Sciences. 468: 45-54. PMID 2425692 DOI: 10.1111/J.1749-6632.1986.Tb42027.X  0.339
1986 Kimmel M, Darzynkiewicz Z, Staiano-Coico L. Stathmokinetic analysis of human epidermal cells in vitro Cell and Tissue Kinetics. 19: 289-304. PMID 2424602 DOI: 10.1111/J.1365-2184.1986.Tb00681.X  0.467
1986 Evenson D, Darzynkiewicz Z, Jost L, Janca F, Ballachey B. Changes in accessibility of DNA to various fluorochromes during spermatogenesis Cytometry. 7: 45-53. PMID 2419055 DOI: 10.1002/Cyto.990070107  0.447
1986 Staiano-Coico L, Higgins PJ, Darzynkiewicz Z, Kimmel M, Gottlieb AB, Pagan-Charry I, Madden MR, Finkelstein JL, Hefton JM. Human keratinocyte culture. Identification and staging of epidermal cell subpopulations. The Journal of Clinical Investigation. 77: 396-404. PMID 2418062 DOI: 10.1172/Jci112317  0.395
1985 Kimmel M, Darzynkiewicz Z, Arino O, Traganos F. Analysis of a cell cycle model based on unequal division of metabolic constituents to daughter cells during cytokinesis. Journal of Theoretical Biology. 110: 637-64. PMID 6084152 DOI: 10.1016/S0022-5193(84)80149-6  0.423
1985 Kapuscinski J, Darzynkiewicz Z. Interactions of antitumor agents Ametantrone and Mitoxantrone (Novatrone) with double-stranded DNA. Biochemical Pharmacology. 34: 4203-13. PMID 4074383 DOI: 10.1016/0006-2952(85)90275-8  0.318
1985 Evenson DP, Lee J, Darzynkiewicz Z, Melamed MR. Rhodamine 123 alters the mitochondrial ultrastructure of cultured L1210 cells. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 33: 353-9. PMID 3980984 DOI: 10.1177/33.4.3980984  0.388
1985 Staiano-Coico L, Stollar BD, Darzynkiewicz Z, Dutkowski R, Weksler ME. Binding of anti-Z-DNA antibodies in quiescent and activated lymphocytes: Relationship to cell cycle progression and chromatin changes Molecular and Cellular Biology. 5: 3270-3273. PMID 3915771 DOI: 10.1128/Mcb.5.11.3270  0.403
1985 Moran R, Darzynkiewicz Z, Staiano-Coico L, Melamed MR. Detection of 5-bromodeoxyuridine (BrdUrd) incorporation by monoclonal antibodies: role of the DNA denaturation step. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 33: 821-7. PMID 3860561 DOI: 10.1177/33.8.3860561  0.46
1985 Darzynkiewicz Z, Traganos F, Kapuscinski J, Melamed MR. Denaturation and condensation of DNA in situ induced by acridine orange in relation to chromatin changes during growth and differentiation of Friend erythroleukemia cells. Cytometry. 6: 195-207. PMID 3858089 DOI: 10.1002/Cyto.990060305  0.479
1985 Melamed J, Darzynkiewicz Z. RNA content and chromatin structure of CHO cells arrested in metaphase by colcemid. Cytometry. 6: 381-5. PMID 2410207 DOI: 10.1002/Cyto.990060417  0.47
1985 Crissman HA, Darzynkiewicz Z, Tobey RA, Steinkamp JA. Normal and perturbed Chinese hamster ovary cells: correlation of DNA, RNA, and protein content by flow cytometry. The Journal of Cell Biology. 101: 141-7. PMID 2409095 DOI: 10.1083/Jcb.101.1.141  0.466
1985 Crissman HA, Darzynkiewicz Z, Tobey RA, Steinkamp JA. Correlated measurements of DNA, RNA, and protein in individual cells by flow cytometry. Science (New York, N.Y.). 228: 1321-4. PMID 2408339 DOI: 10.1126/Science.2408339  0.444
1984 Traganos F, Darzynkiewicz Z, Bueti C, Melamed MR. Effects of a prospective antitumor agent, 1,4-bis(2'-chloroethyl)-1,4-diazabicyclo-[2.2.1] heptane diperchlorate, on cultured mammalian cells. Cancer Investigation. 2: 1-13. PMID 6584191 DOI: 10.3109/07357908409020281  0.458
1984 Darzynkiewicz Z, Carter S. Compound 48/80 impairs cytokinesis in murine leukemic cells. Journal of Cellular Physiology. 119: 1-6. PMID 6546236 DOI: 10.1002/Jcp.1041190102  0.418
1984 Darzynkiewicz Z, Carter S, Kimmel M. Effect of [3H]UdR on the cell-cycle progression of L1210 cells Cell and Tissue Kinetics. 17: 641-655. PMID 6488281 DOI: 10.1111/J.1365-2184.1984.Tb00623.X  0.392
1984 Darzynkiewicz Z, Traganos F, Kapuscinski J, Staiano-Coico L, Melamed MR. Accessibility of DNA in situ to various fluorochromes: relationship to chromatin changes during erythroid differentiation of Friend leukemia cells. Cytometry. 5: 355-63. PMID 6468176 DOI: 10.1002/Cyto.990050411  0.471
1984 Kapuscinski J, Darzynkiewicz Z. Denaturation of nucleic acids induced by intercalating agents. Biochemical and biophysical properties of acridine orange-DNA complexes. Journal of Biomolecular Structure & Dynamics. 1: 1485-99. PMID 6400830 DOI: 10.1080/07391102.1984.10507532  0.307
1984 Traganos F, Higgins PJ, Bueti C, Darzynkiewicz Z, Melamed MR. Effects of Retinoic Acid Versus Dimethyl Sulfoxide on Friend Erythroleukemia Cell Growth. II. Induction of Quiescent, Nonproliferating Cells Journal of the National Cancer Institute. 73: 205-218. DOI: 10.1093/Jnci/73.1.205  0.483
1984 Traganos F, Bueti C, Darzynkiewicz Z, Melamed MR. Effects of retinoic acid versus dimethyl sulfoxide on friend erythroleukemia cell growth. I: Cell proliferation, RNA content, and protein content Journal of the National Cancer Institute. 73: 193-204. DOI: 10.1093/Jnci/73.1.193  0.414
1983 Staiano-Coico L, Darzynkiewicz Z, Melamed MR, Weksler M. Changes in DNA content of human blood mononuclear cells with senescence. Cytometry. 3: 79-83. PMID 7140482 DOI: 10.1002/Cyto.990030203  0.452
1983 Darzynkiewicz Z, Traganos F, Melamed MR. Distinction between 5-bromodeoxyuridine labeled and unlabeled mitotic cells by flow cytometry. Cytometry. 3: 345-8. PMID 6839883 DOI: 10.1002/Cyto.990030507  0.515
1983 Staiano-Coico L, Darzynkiewicz Z, Hefton JM, Dutkowski R, Darlington GJ, Weksler ME. Increased sensitivity of lymphocytes from people over 65 to cell cycle arrest and chromosomal damage. Science (New York, N.Y.). 219: 1335-7. PMID 6828861 DOI: 10.1126/Science.6828861  0.374
1983 Kimmel M, Traganos F, Darzynkiewicz Z. Do all daughter cells enter the 'indeterminate' ('A') state of the cell cycle? Analysis of stathmokinetic experiments on L1210 cells Cytometry. 4: 191-201. PMID 6661986 DOI: 10.1002/Cyto.990040302  0.425
1983 Potmesil M, Levin M, Traganos F, Israel M, Darzynkiewicz Z, Khetarpal VK, Silber R. In vivo effects of adriamycin or N-trifluoroacetyladriamycin-14-valerate on a mouse lymphoma. European Journal of Cancer & Clinical Oncology. 19: 109-22. PMID 6602051 DOI: 10.1016/0277-5379(83)90405-4  0.433
1983 Darzynkiewicz Z, Evenson D, Kapuscinski J, Melamed MR. Denaturation of RNA and DNA in situ induced by acridine orange. Experimental Cell Research. 148: 31-46. PMID 6195003 DOI: 10.1016/0014-4827(83)90185-4  0.431
1983 Higgins PJ, Darzynkiewicz Z, Melamed MR. Secretion of albumin and alpha-foetoprotein by dimethylsulphoxide-stimulated hepatocellular carcinoma cells. British Journal of Cancer. 48: 485-93. PMID 6194807 DOI: 10.1038/Bjc.1983.221  0.437
1983 Darzynkiewicz Z. Molecular interactions and cellular changes during the cell cycle. Pharmacology & Therapeutics. 21: 143-88. PMID 6194535 DOI: 10.1016/0163-7258(83)90071-2  0.359
1983 Piwnicka M, Darzynkiewicz Z, Melamed MR. RNA and DNA content of isolated cell nuclei measured by multiparameter flow cytometry. Cytometry. 3: 269-75. PMID 6185286 DOI: 10.1002/Cyto.990030407  0.441
1983 Darzynkiewicz Z, Crissman H, Traganos F, Steinkamp J. Cell heterogeneity during the cell cycle. Journal of Cellular Physiology. 113: 465-74. PMID 6184378 DOI: 10.1002/Jcp.1041130316  0.438
1982 Darzynkiewicz Z, Traganos F, Xue SB, Melamed MR. Effect of n-butyrate on cell cycle progression and in situ chromatin structure of L1210 cells. Experimental Cell Research. 136: 279-93. PMID 7308309 DOI: 10.1016/0014-4827(81)90006-9  0.453
1982 Evenson DP, Darzynkiewicz Z, Melamed MR. Simultaneous measurement by flow cytometry of sperm cell viability and mitochondrial membrane potential related to cell motility. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 30: 279-80. PMID 6174566 DOI: 10.1177/30.3.6174566  0.37
1982 Traganos F, Darzynkiewicz Z, Melamed MR. The ratio of RNA to total nucleic acid content as a quantitative measure of unbalanced cell growth. Cytometry. 2: 212-8. PMID 6173180 DOI: 10.1002/Cyto.990020403  0.438
1982 Darzynkiewicz Z, Traganos F, Melamed MR. New cell cycle compartments identified by multiparameter flow cytometry. Cytometry. 1: 98-108. PMID 6170495 DOI: 10.1002/Cyto.990010203  0.503
1981 Evenson DP, Darzynkiewicz Z, Melamed MR. Relation of mammalian sperm chromatin heterogeneity to fertility. Science (New York, N.Y.). 210: 1131-3. PMID 7444440 DOI: 10.1126/Science.7444440  0.321
1981 Olszewski W, Darzynkiewicz Z, Rosen PP, Schwartz MK, Melamed MR. Flow cytometry of breast carcinoma: II. Relation of tumor cell cycle distribution to histology and estrogen receptor. Cancer. 48: 985-8. PMID 7272941 DOI: 10.1002/1097-0142(19810815)48:4<985::Aid-Cncr2820480422>3.0.Co;2-Q  0.313
1981 Olszewski W, Darzynkiewicz Z, Rosen PP, Schwartz MK, Melamed MR. Flow cytometry of breast carcinoma: I. Relation of DNA ploidy level to histology and estrogen receptor. Cancer. 48: 980-4. PMID 7272940 DOI: 10.1002/1097-0142(19810815)48:4<980::Aid-Cncr2820480421>3.0.Co;2-7  0.366
1981 Darzynkiewicz Z, Traganos F, Melamed MR. Detergent treatment as an alternative to cell fixation for flow cytometry. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 29: 329-30. PMID 7252123 DOI: 10.1177/29.2.7252123  0.515
1981 Kapuscinski J, Darzynkiewicz Z, Traganos F, Melamed MR. Interactions of a new antitumor agent, 1,4-dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]-ethyl]amino]-9,10-anthracenedione, with nucleic acids. Biochemical Pharmacology. 30: 231-40. PMID 7225141 DOI: 10.1016/0006-2952(81)90083-6  0.37
1981 Darzynkiewicz Z, Staiano-Coico L, Melamed MR. Increased mitochondrial uptake of rhodamine 123 during lymphocyte stimulation. Proceedings of the National Academy of Sciences of the United States of America. 78: 2383-7. PMID 6941298 DOI: 10.1073/Pnas.78.4.2383  0.437
1981 Darzynkiewicz Z, Traganos F, Xue S, Staiano-Coico L, Melamed MR. Rapid analysis of drug effects on the cell cycle. Cytometry. 1: 279-86. PMID 6167411 DOI: 10.1002/Cyto.990010407  0.478
1981 Darzynkiewicz Z, Sharpless T, Staiano-Coico L, Melamed MR. Subcompartments of the G1 phase of cell cycle detected by flow cytometry. Proceedings of the National Academy of Sciences of the United States of America. 77: 6696-9. PMID 6161370 DOI: 10.1073/Pnas.77.11.6696  0.42
1980 Evenson DP, Darzynkiewicz Z, Melamed MR. Comparison of human and mouse sperm chromatin structure by flow cytometry. Chromosoma. 78: 225-38. PMID 7389511 DOI: 10.1007/Bf00328394  0.359
1980 Collste LG, Darzynkiewicz Z, Traganos F, Sharpless TK, Sogani P, Grabstald H, Whitmore WF, Melamed MR. Flow cytometry in bladder cancer detection and evaluation using acridine orange metachromatic nucleic acid staining of irrigation cytology specimens. The Journal of Urology. 123: 478-85. PMID 7365880 DOI: 10.1016/S0022-5347(17)55980-7  0.35
1980 Mora M, Darzynkiewicz Z, Baserga R. DNA synthesis and cell division in a mammalian cell mutant temperature sensitive for the processing of ribosomal RNA. Experimental Cell Research. 125: 241-9. PMID 7351217 DOI: 10.1016/0014-4827(80)90208-6  0.311
1980 Collste LG, Devonec M, Darzynkiewicz Z, Traganos F, Sharpless TK, Whitmore WF, Melamed MR. Bladder cancer diagnosis by flow cytometry. Correlation between cell samples from biopsy and bladder irrigation fluid. Cancer. 45: 2389-94. PMID 6155204 DOI: 10.1002/1097-0142(19800501)45:9<2389::Aid-Cncr2820450925>3.0.Co;2-Y  0.358
1980 Collste LG, Darzynkiewicz Z, Traganos F, Sharpless TK, Devonec M, Claps ML, Whitmore WF, Melamed MR. Cell-cycle distribution of urothelial tumour cells as measured by flow cytometry. British Journal of Cancer. 40: 872-7. PMID 526428 DOI: 10.1038/Bjc.1979.279  0.459
1980 Drapkin RL, Adreeff M, Koziner B, Strife A, Wisniewski D, Darzynkiewicz Z, Melamed MR, Clarkson B. Subpopulations of human peripheral blood cells: analysis of granulocytic progenitor cells by flow cytometry and immunologic surface markers. American Journal of Hematology. 7: 163-72. PMID 94243 DOI: 10.1002/Ajh.2830070209  0.382
1980 Andreeff M, Darzynkiewicz Z, Sharpless T, Clarkson B, Melamed M. Discrimination of human leukemia subtypes by flow cytometric analysis of cellular DNA and RNA Blood. 55: 282-293. DOI: 10.1182/Blood.V55.2.282.Bloodjournal552282  0.458
1980 Andreeff M, Darzynkiewicz Z, Sharpless T, Clarkson B, Melamed M. Discrimination of human leukemia subtypes by flow cytometric analysis of cellular DNA and RNA Blood. 55: 282-293. DOI: 10.1182/blood.V55.2.282.bloodjournal552282  0.351
1980 Traganos F, Staiano-Coico L, Darzynkiewicz Z, Melamed MR. Effects of Prospidine on Survival and Growth of Mammalian Cells in Culture Journal of the National Cancer Institute. 65: 993-999. DOI: 10.1093/Jnci/65.5.993  0.461
1980 Evenson DP, Traganos F, Darzynkiewicz Z, Staiano-Coico L, Melamed MR. Effects of 9,10-Anthracenedione, 1,4-bis[[2-[(2-hydroxyethyl)amino]-ethyl]amino]-, diacetate on Cell Morphology and Nucleic Acids of Friend Leukemia Cells Journal of the National Cancer Institute. 64: 857-866. DOI: 10.1093/Jnci/64.4.857  0.504
1979 Darzynkiewicz Z, Evenson DP, Staiano-Coico L, Sharpless TK, Melamed ML. Correlation between cell cycle duration and RNA content. Journal of Cellular Physiology. 100: 425-38. PMID 489667 DOI: 10.1002/Jcp.1041000306  0.397
1979 Darzynkiewicz Z, Evenson D, Staiano-Coico L, Sharpless T, Melamed MR. Relationship between RNA content and progression of lymphocytes through S phase of cell cycle. Proceedings of the National Academy of Sciences of the United States of America. 76: 358-62. PMID 284352 DOI: 10.1073/Pnas.76.1.358  0.399
1979 Darzynkiewicz Z, Traganos F, Andreeff M, Sharpless T, Melamed MR. Different sensitivity of chromatin to acid denaturation in quiescent and cycling cells as revealed by flow cytometry. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 27: 478-85. PMID 86572 DOI: 10.1177/27.1.86572  0.509
1979 Collste L, Darzynkiewicz Z, Traganos F, Sharpless TK, Whitmore WF, Melamed MR. Identification of polymorphonuclear leukocytes in cytologic samples for flow cytometry. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 27: 390-3. PMID 86568 DOI: 10.1177/27.1.86568  0.411
1979 Traganos F, Darzynkiewicz Z, Sharpless TK, Melamed MR. Erythroid differentiation of Friend leukemia cells as studied by acridine orange staining and flow cytometry. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 27: 382-9. PMID 86567 DOI: 10.1177/27.1.86567  0.524
1978 Kurland JI, Traganos F, Darzynkiewicz Z, Moore MA. Macrophage-mediated cytostasis of neoplastic hemopoietic cells: cytofluorometric analysis of the reversible cell cycle block. Cellular Immunology. 36: 318-30. PMID 630611 DOI: 10.1016/0008-8749(78)90276-9  0.425
1978 Andreeff M, Beck JD, Darzynkiewicz Z, Traganos F, Gupta S, Melamed MR, Good RA. RNA content in human lymphocyte subpopulations. Proceedings of the National Academy of Sciences of the United States of America. 75: 1938-42. PMID 306108 DOI: 10.1073/Pnas.75.4.1938  0.378
1978 Darźynkiewicz Z, Andreeff M, Traganos F, Sharpless T, Melamed MR. Discrimination of cycling and non-cycling lymphocytes by BUdR-suppressed acridine orange fluorescence in a flow cytometric system. Experimental Cell Research. 115: 31-5. PMID 79494 DOI: 10.1016/0014-4827(78)90398-1  0.453
1978 Darzynkiewicz Z, Traganos F, Sharpless T, Melamed MR. Interphase and metaphase chromatin. Different stainability of DNA with acridine orange after treatment at low pH. Experimental Cell Research. 110: 201-14. PMID 72675 DOI: 10.1016/0014-4827(77)90286-5  0.477
1978 Beck JD, Haghbin M, Andreeff M, Darzynkiewicz Z, Good RA, Gupta S. 578 SURFACE MARKERS AND RNA CONTENT OF LEUKEMIC BLASTS IN ACUTE MYELOID LEUKEMIA OF CHILDHOOD AS A MEASURE OF STAGE OF MATURATION Pediatric Research. 12: 460-460. DOI: 10.1203/00006450-197804001-00583  0.415
1977 Traganos F, Gorski AJ, Darzynkiewicz Z, Sharpless T, Melamed MR. Rapid multiparameter analysis of cell stimulation in mixed lymphocyte culture reactions. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 25: 881-7. PMID 142787 DOI: 10.1177/25.7.142787  0.414
1977 Traganos F, Darzynkiewicz Z, Sharpless T, Melamed MR. Nucleic acid content and cell cycle distribution of five human bladder cell lines analysed by flow cytofluorometry. International Journal of Cancer. 20: 30-6. PMID 71271 DOI: 10.1002/Ijc.2910200107  0.483
1977 Darzynkiewicz Z, Traganos F, Sharpless T, Melamed MR. Recognition of cells in mitosis by flow cytofluormetry. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 25: 875-80. PMID 70457 DOI: 10.1177/25.7.70457  0.442
1977 Traganos F, Darzynkiewicz Z, Sharpless T, Melamed MR. Simultaneous staining of ribonucleic and deoxyribonucleic acids in unfixed cells using acridine orange in a flow cytofluorometric system. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 25: 46-56. PMID 64567 DOI: 10.1177/25.1.64567  0.489
1977 Darzynkiewicz Z, Traganos F, Sharpless T, Melamed MR. Different sensitivity of DNA in situ in interphase and metaphase chromatin to heat denaturation. The Journal of Cell Biology. 73: 128-38. PMID 16017 DOI: 10.1083/Jcb.73.1.128  0.494
1976 Darzynkiewicz Z, Traganos F, Arlin ZA, Sharpless AT, Melamed MR. Cytofluorometric studies on conformation of nucleic acids in situ. II. Denaturation of deoxyribonucleic acid. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 24: 49-58. PMID 1254935 DOI: 10.1177/24.1.1254935  0.445
1976 Traganos F, Darzynkiewicz Z, Sharpless T, Melamed MR. Cytofluorometric studies on conformation of nucleic acids in situ. I. Restriction of acridine orange binding by chromatin proteins. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 24: 40-8. PMID 1254934 DOI: 10.1177/24.1.1254934  0.429
1976 Darzynkiewicz Z, Traganos F, Sharpless T, Melamed MR. DNA denaturation in situ. Effect of divalent cations and alcohols. The Journal of Cell Biology. 68: 1-10. PMID 1245542 DOI: 10.1083/Jcb.68.1.1  0.377
1976 Darzynkiewicz Z, Traganos F, Sharpless T, Melamed MR. Effect of 0.25 n sodium chloride treatment on DNA denaturation in situ in thymus lymphocytes. Experimental Cell Research. 100: 393-6. PMID 1084834 DOI: 10.1016/0014-4827(76)90164-6  0.382
1976 Darzynkiewicz Z, Traganos F, Sharpless T, Melamed MR. Lymphocyte stimulation: a rapid multiparameter analysis. Proceedings of the National Academy of Sciences of the United States of America. 73: 2881-4. PMID 822422 DOI: 10.1073/Pnas.73.8.2881  0.398
1976 Darzynkiewicz Z, Tragnos F, Sharpless T, Friend C, Melamed MR. Nuclear chromatin changes during erythroid differentiation of friend virus induced leukemic cells. Experimental Cell Research. 99: 301-9. PMID 57877 DOI: 10.1016/0014-4827(76)90587-5  0.451
1976 Darzynkiewicz Z, Traganos F, Sharpless T, Melamed MR. Conformation of RNA in situ as studied by acridine orange staining and automated cytofluorometry. Experimental Cell Research. 95: 143-53. PMID 53154 DOI: 10.1016/0014-4827(75)90619-9  0.351
1975 Darzynkiewicz Z, Traganos F, Sharpless T, Melamed MR. Thermal denaturation of DNA in situ as studied by acridine orange staining and automated cytofluorometry. Experimental Cell Research. 90: 411-28. PMID 46199 DOI: 10.1016/0014-4827(75)90331-6  0.473
1974 Darzynkiewicz Z. Radiation-induced DNA synthesis in normal and stimulated human lymphocytes. Experimental Cell Research. 69: 356-60. PMID 5163631 DOI: 10.1016/0014-4827(71)90235-7  0.383
1974 Darzynkiewicz Z, Arnason BG. Suppression of RNA synthesis in lymphocytes by inhibitors of proteolytic enzymes. Experimental Cell Research. 85: 95-104. PMID 4545277 DOI: 10.1016/0014-4827(74)90217-1  0.368
1974 Darzynkiewicz Z, Chelmicka-Szorc E, Arnason BG. Chick-erythrocyte nucleus reactivation in heterokaryons: suppression by inhibitors of proteolytic enzymes. Proceedings of the National Academy of Sciences of the United States of America. 71: 644-7. PMID 4522779 DOI: 10.1073/Pnas.71.3.644  0.394
1974 Darzynkiewicz Z, Chelmicka-Szorc E, Arnason BG. Suppressive effect of protease inhibitors on heterokaryons containing chick erythrocyte nuclei. Experimental Cell Research. 87: 333-45. PMID 4472333 DOI: 10.1016/0014-4827(74)90489-3  0.34
1974 Darzynkiewicz Z. Radiation-induced DNA synthesis in nuclei of hen erythrocytes reactivated in heterokaryons. Experimental Cell Research. 69: 477-81. PMID 4360911 DOI: 10.1016/0014-4827(71)90260-6  0.381
1974 Darzynkiewicz Z, Traganos F, Sharpless T, Melamed M. Thermally-induced changes in chromatin of isolated nuclei and of intact cells as revealed by acridine orange staining. Biochemical and Biophysical Research Communications. 59: 392-9. PMID 4135307 DOI: 10.1016/S0006-291X(74)80219-6  0.438
1973 Gledhill BL, Darzynkiewicz Z. Unscheduled synthesis of DNA during mammalian spermatogenesis in response to UV irradiation. The Journal of Experimental Zoology. 183: 375-82. PMID 4697408 DOI: 10.1002/Jez.1401830311  0.43
1973 Andersson J, Darzynkiewicz Z. Nucleoprotein changes and uridine incorporation in rat thymocytes. II. Effect of treatment with anti-thymocyte serum in vitro. Experimental Cell Research. 75: 417-23. PMID 4674694 DOI: 10.1016/0014-4827(72)90448-X  0.328
1973 Andersson J, Darzynkiewicz Z. Nucleoprotein changes and uridine incorporation in rat thymus lymphocytes. I. Cellular characterization of age-dependent thymus involution. Experimental Cell Research. 75: 410-6. PMID 4644250 DOI: 10.1016/0014-4827(72)90447-8  0.392
1973 Darzynkiewicz Z. Detection of DNA polymerase activity in fixed cells. Experimental Cell Research. 80: 483-6. PMID 4583195 DOI: 10.1016/0014-4827(73)90329-7  0.461
1972 Darzynkiewicz Z, Chelmicka-Szorc E. Unscheduled DNA synthesis in hen erythrocyte nuclei reactivated in heterokaryons. Experimental Cell Research. 74: 131-9. PMID 4672468 DOI: 10.1016/0014-4827(72)90488-0  0.424
1972 Darzynkiewicz Z, Chelmicka-Szorc E, Arnason BG. UV-induced DNA synthesis in Xeroderma pigmentosum nuclei in heterokaryons. Experimental Cell Research. 74: 602-6. PMID 4343024 DOI: 10.1016/0014-4827(72)90427-2  0.385
1972 Ritzén M, Carlsson SA, Darzynkiewicz Z. Cytochemical evidence of nucleoprotein changes in rat adrenal cortex following hypophysectomy or dexamethasone suppression. Experimental Cell Research. 70: 462-5. PMID 4110309 DOI: 10.1016/0014-4827(72)90167-X  0.337
1971 Darzynkiewicz Z, Jacobson B. Effect of prednisolone on thymus lymphocytes. II. Studies on 3 H-actinomycin D Binding and RNA polymerase activity of isolate nuclei. Experimental Cell Research. 67: 49-60. PMID 5569203 DOI: 10.1016/0014-4827(71)90620-3  0.365
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