| Year |
Citation |
Score |
| 2023 |
Chai YC, Mieyal JJ. Glutathione and Glutaredoxin-Key Players in Cellular Redox Homeostasis and Signaling. Antioxidants (Basel, Switzerland). 12. PMID 37627548 DOI: 10.3390/antiox12081553 |
0.444 |
|
| 2018 |
Gorelenkova Miller O, Mieyal JJ. Critical Roles of Glutaredoxin in Brain Cells-Implications for Parkinson's Disease. Antioxidants & Redox Signaling. PMID 29183158 DOI: 10.1089/ars.2017.7411 |
0.316 |
|
| 2017 |
Gorelenkova Miller O, Cole KS, Emerson CC, Allimuthu D, Golczak M, Stewart PL, Weerapana E, Adams DJ, Mieyal JJ. Novel chloroacetamido compound CWR-J02 is an anti-inflammatory glutaredoxin-1 inhibitor. Plos One. 12: e0187991. PMID 29155853 DOI: 10.1371/Journal.Pone.0187991 |
0.325 |
|
| 2016 |
Gorelenkova Miller O, Behring JB, Siedlak SL, Jiang S, Matsui R, Bachschmid MM, Zhu X, Mieyal JJ. Upregulation of Glutaredoxin-1 Activates Microglia and Promotes Neurodegeneration: Implications for Parkinson's disease. Antioxidants & Redox Signaling. PMID 27224303 DOI: 10.1089/Ars.2015.6598 |
0.366 |
|
| 2016 |
Johnson WM, Golczak M, Choe K, Currran PL, Gorelenkova Miller O, Yao C, Wang W, Lin J, Milkovic NM, Ray A, Ravindranath V, Zhu X, Wilson MA, Wilson-Delfosse AL, Chen SG, ... Mieyal JJ, et al. Regulation of DJ-1 by glutaredoxin 1 in vivo - implications for Parkinson's disease. Biochemistry. PMID 26894491 DOI: 10.1021/Acs.Biochem.5B01132 |
0.507 |
|
| 2015 |
Johnson WM, Wilson-Delfosse AL, Chen SG, Mieyal JJ. The roles of redox enzymes in Parkinson's disease: Focus on glutaredoxin. Therapeutic Targets For Neurological Diseases. 2. PMID 26097894 DOI: 10.14800/Ttnd.790 |
0.385 |
|
| 2015 |
Gorelenkova Miller O, Mieyal JJ. Sulfhydryl-mediated redox signaling in inflammation: role in neurodegenerative diseases. Archives of Toxicology. 89: 1439-67. PMID 25827102 DOI: 10.1007/s00204-015-1496-7 |
0.401 |
|
| 2015 |
Johnson WM, Yao C, Siedlak SL, Wang W, Zhu X, Caldwell GA, Wilson-Delfosse AL, Mieyal JJ, Chen SG. Glutaredoxin deficiency exacerbates neurodegeneration in C. elegans models of Parkinson's disease. Human Molecular Genetics. 24: 1322-35. PMID 25355420 DOI: 10.1093/Hmg/Ddu542 |
0.404 |
|
| 2014 |
Qanungo S, Uys JD, Manevich Y, Distler AM, Shaner B, Hill EG, Mieyal JJ, Lemasters JJ, Townsend DM, Nieminen AL. N-acetyl-L-cysteine sensitizes pancreatic cancers to gemcitabine by targeting the NFκB pathway. Biomedicine & Pharmacotherapy = BioméDecine & PharmacothéRapie. 68: 855-64. PMID 25257100 DOI: 10.1016/J.Biopha.2014.08.007 |
0.378 |
|
| 2013 |
Gao XH, Qanungo S, Pai HV, Starke DW, Steller KM, Fujioka H, Lesnefsky EJ, Kerner J, Rosca MG, Hoppel CL, Mieyal JJ. Aging-dependent changes in rat heart mitochondrial glutaredoxins--Implications for redox regulation. Redox Biology. 1: 586-98. PMID 25126518 DOI: 10.1016/J.Redox.2013.10.010 |
0.34 |
|
| 2013 |
Yao C, Johnson WM, Gao Y, Wang W, Zhang J, Deak M, Alessi DR, Zhu X, Mieyal JJ, Roder H, Wilson-Delfosse AL, Chen SG. Kinase inhibitors arrest neurodegeneration in cell and C. elegans models of LRRK2 toxicity. Human Molecular Genetics. 22: 328-44. PMID 23065705 DOI: 10.1093/Hmg/Dds431 |
0.314 |
|
| 2012 |
Johnson WM, Wilson-Delfosse AL, Mieyal JJ. Dysregulation of glutathione homeostasis in neurodegenerative diseases. Nutrients. 4: 1399-440. PMID 23201762 DOI: 10.3390/Nu4101399 |
0.475 |
|
| 2012 |
Allen EM, Mieyal JJ. Protein-thiol oxidation and cell death: regulatory role of glutaredoxins. Antioxidants & Redox Signaling. 17: 1748-63. PMID 22530666 DOI: 10.1089/Ars.2012.4644 |
0.507 |
|
| 2012 |
Mieyal JJ, Chock PB. Posttranslational modification of cysteine in redox signaling and oxidative stress: Focus on s-glutathionylation. Antioxidants & Redox Signaling. 16: 471-5. PMID 22136616 DOI: 10.1089/Ars.2011.4454 |
0.518 |
|
| 2012 |
Sabens Liedhegner EA, Gao XH, Mieyal JJ. Mechanisms of altered redox regulation in neurodegenerative diseases--focus on S--glutathionylation. Antioxidants & Redox Signaling. 16: 543-66. PMID 22066468 DOI: 10.1089/Ars.2011.4119 |
0.537 |
|
| 2012 |
Qanungo S, Uys JdK, Distler A, Mieyal JJ, Lemasters JJ, Townsend DM, Nieminen A. Abstract 1316: N-acetyl-L-cysteine sensitizes pancreatic cancer therapy by targeting NFκB pathway: Translation into animal model Cancer Research. 72: 1316-1316. DOI: 10.1158/1538-7445.Am2012-1316 |
0.317 |
|
| 2011 |
Gonzalez-Dosal R, Horan KA, Rahbek SH, Ichijo H, Chen ZJ, Mieyal JJ, Hartmann R, Paludan SR. Hsv infection induces production of ros, which potentiate signaling from pattern recognition receptors: Role for s-glutathionylation of traf3 and 6 Plos Pathogens. 7. PMID 21949653 DOI: 10.1371/Journal.Ppat.1002250 |
0.353 |
|
| 2011 |
Liedhegner EA, Steller KM, Mieyal JJ. Levodopa activates apoptosis signaling kinase 1 (ASK1) and promotes apoptosis in a neuronal model: implications for the treatment of Parkinson's disease. Chemical Research in Toxicology. 24: 1644-52. PMID 21815648 DOI: 10.1021/Tx200082H |
0.457 |
|
| 2010 |
Sabens EA, Distler AM, Mieyal JJ. Levodopa deactivates enzymes that regulate thiol-disulfide homeostasis and promotes neuronal cell death: implications for therapy of Parkinson's disease. Biochemistry. 49: 2715-24. PMID 20141169 DOI: 10.1021/Bi9018658 |
0.633 |
|
| 2010 |
Gallogly MM, Shelton MD, Qanungo S, Pai HV, Starke DW, Hoppel CL, Lesnefsky EJ, Mieyal JJ. Glutaredoxin regulates apoptosis in cardiomyocytes via NFkappaB targets Bcl-2 and Bcl-xL: implications for cardiac aging. Antioxidants & Redox Signaling. 12: 1339-53. PMID 19938943 DOI: 10.1089/Ars.2009.2791 |
0.375 |
|
| 2009 |
Park JW, Mieyal JJ, Rhee SG, Chock PB. Deglutathionylation of 2-Cys peroxiredoxin is specifically catalyzed by sulfiredoxin. The Journal of Biological Chemistry. 284: 23364-74. PMID 19561357 DOI: 10.1074/Jbc.M109.021394 |
0.451 |
|
| 2009 |
Zhu X, Gallogly MM, Mieyal JJ, Anderson VE, Sayre LM. Covalent cross-linking of glutathione and carnosine to proteins by 4-oxo-2-nonenal. Chemical Research in Toxicology. 22: 1050-9. PMID 19480392 DOI: 10.1021/Tx9000144 |
0.38 |
|
| 2009 |
Gallogly MM, Starke DW, Mieyal JJ. Mechanistic and kinetic details of catalysis of thiol-disulfide exchange by glutaredoxins and potential mechanisms of regulation. Antioxidants & Redox Signaling. 11: 1059-81. PMID 19119916 DOI: 10.1089/Ars.2008.2291 |
0.494 |
|
| 2009 |
Shelton MD, Distler AM, Kern TS, Mieyal JJ. Glutaredoxin regulates autocrine and paracrine proinflammatory responses in retinal glial (muller) cells. The Journal of Biological Chemistry. 284: 4760-6. PMID 19074435 DOI: 10.1074/Jbc.M805464200 |
0.402 |
|
| 2008 |
Gallogly MM, Starke DW, Leonberg AK, Ospina SM, Mieyal JJ. Kinetic and mechanistic characterization and versatile catalytic properties of mammalian glutaredoxin 2: implications for intracellular roles. Biochemistry. 47: 11144-57. PMID 18816065 DOI: 10.1021/Bi800966V |
0.425 |
|
| 2008 |
Mieyal JJ, Gallogly MM, Qanungo S, Sabens EA, Shelton MD. Molecular mechanisms and clinical implications of reversible protein S-glutathionylation. Antioxidants & Redox Signaling. 10: 1941-88. PMID 18774901 DOI: 10.1089/Ars.2008.2089 |
0.644 |
|
| 2008 |
Shelton MD, Mieyal JJ. Regulation by reversible S-glutathionylation: molecular targets implicated in inflammatory diseases. Molecules and Cells. 25: 332-46. PMID 18483468 |
0.331 |
|
| 2007 |
Ho YS, Xiong Y, Ho DS, Gao J, Chua BH, Pai H, Mieyal JJ. Targeted disruption of the glutaredoxin 1 gene does not sensitize adult mice to tissue injury induced by ischemia/reperfusion and hyperoxia. Free Radical Biology & Medicine. 43: 1299-312. PMID 17893043 DOI: 10.1016/J.Freeradbiomed.2007.07.025 |
0.413 |
|
| 2007 |
Pai HV, Starke DW, Lesnefsky EJ, Hoppel CL, Mieyal JJ. What is the functional significance of the unique location of glutaredoxin 1 (GRx1) in the intermembrane space of mitochondria? Antioxidants & Redox Signaling. 9: 2027-33. PMID 17845131 DOI: 10.1089/Ars.2007.1642 |
0.365 |
|
| 2007 |
Gallogly MM, Mieyal JJ. Mechanisms of reversible protein glutathionylation in redox signaling and oxidative stress. Current Opinion in Pharmacology. 7: 381-91. PMID 17662654 DOI: 10.1016/J.Coph.2007.06.003 |
0.518 |
|
| 2007 |
Qanungo S, Starke DW, Pai HV, Mieyal JJ, Nieminen AL. Glutathione supplementation potentiates hypoxic apoptosis by S-glutathionylation of p65-NFkappaB. The Journal of Biological Chemistry. 282: 18427-36. PMID 17468103 DOI: 10.1074/Jbc.M610934200 |
0.387 |
|
| 2007 |
Shelton MD, Kern TS, Mieyal JJ. Glutaredoxin regulates nuclear factor kappa-B and intercellular adhesion molecule in Müller cells: model of diabetic retinopathy. The Journal of Biological Chemistry. 282: 12467-74. PMID 17324929 DOI: 10.1074/Jbc.M610863200 |
0.37 |
|
| 2007 |
Gallogly MM, Starke DW, Leonberg AK, Mieyal JJ. Kinetics of the Mammalian Glutaredoxins: GRx2 Is Less Active, But Mimics the Catalytic Mechanism of GRx1 The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A274-A |
0.353 |
|
| 2006 |
Wang Y, Qiao M, Mieyal JJ, Asmis LM, Asmis R. Molecular mechanism of glutathione-mediated protection from oxidized low-density lipoprotein-induced cell injury in human macrophages: role of glutathione reductase and glutaredoxin. Free Radical Biology & Medicine. 41: 775-85. PMID 16895798 DOI: 10.1016/J.Freeradbiomed.2006.05.029 |
0.446 |
|
| 2006 |
Srinivasan U, Bala A, Jao SC, Starke DW, Jordan TW, Mieyal JJ. Selective inactivation of glutaredoxin by sporidesmin and other epidithiopiperazinediones. Biochemistry. 45: 8978-87. PMID 16846241 DOI: 10.1021/Bi060440O |
0.5 |
|
| 2006 |
Jao SC, English Ospina SM, Berdis AJ, Starke DW, Post CB, Mieyal JJ. Computational and mutational analysis of human glutaredoxin (thioltransferase): probing the molecular basis of the low pKa of cysteine 22 and its role in catalysis. Biochemistry. 45: 4785-96. PMID 16605247 DOI: 10.1021/Bi0516327 |
0.358 |
|
| 2005 |
Asmis R, Wang Y, Xu L, Kisgati M, Begley JG, Mieyal JJ. A novel thiol oxidation-based mechanism for adriamycin-induced cell injury in human macrophages. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 1866-8. PMID 16160061 DOI: 10.1096/Fj.04-2991Fje |
0.363 |
|
| 2005 |
Shelton MD, Chock PB, Mieyal JJ. Glutaredoxin: role in reversible protein s-glutathionylation and regulation of redox signal transduction and protein translocation. Antioxidants & Redox Signaling. 7: 348-66. PMID 15706083 DOI: 10.1089/Ars.2005.7.348 |
0.501 |
|
| 2003 |
Biaglow JE, Lee I, Donahue J, Held K, Mieyal J, Dewhirst M, Tuttle S. Glutathione depletion or radiation treatment alters respiration and induces apoptosis in R3230Ac mammary carcinoma. Advances in Experimental Medicine and Biology. 530: 153-64. PMID 14562713 DOI: 10.1007/978-1-4615-0075-9_15 |
0.313 |
|
| 2003 |
Nulton-Persson AC, Starke DW, Mieyal JJ, Szweda LI. Reversible inactivation of alpha-ketoglutarate dehydrogenase in response to alterations in the mitochondrial glutathione status. Biochemistry. 42: 4235-42. PMID 12680778 DOI: 10.1021/Bi027370F |
0.411 |
|
| 2003 |
Biaglow JE, Ayene IS, Koch CJ, Donahue J, Stamato TD, Mieyal JJ, Tuttle SW. Radiation response of cells during altered protein thiol redox. Radiation Research. 159: 484-94. PMID 12643793 DOI: 10.1667/0033-7587(2003)159[0484:Rrocda]2.0.Co;2 |
0.365 |
|
| 2003 |
Starke DW, Chock PB, Mieyal JJ. Glutathione-thiyl radical scavenging and transferase properties of human glutaredoxin (thioltransferase). Potential role in redox signal transduction. The Journal of Biological Chemistry. 278: 14607-13. PMID 12556467 DOI: 10.1074/Jbc.M210434200 |
0.458 |
|
| 2002 |
Ehrhart J, Gluck M, Mieyal J, Zeevalk GD. Functional glutaredoxin (thioltransferase) activity in rat brain and liver mitochondria. Parkinsonism & Related Disorders. 8: 395-400. PMID 12217626 DOI: 10.1016/S1353-8020(02)00020-2 |
0.394 |
|
| 2001 |
Wang J, Boja ES, Tan W, Tekle E, Fales HM, English S, Mieyal JJ, Chock PB. Reversible glutathionylation regulates actin polymerization in A431 cells. The Journal of Biological Chemistry. 276: 47763-6. PMID 11684673 DOI: 10.1074/Jbc.C100415200 |
0.336 |
|
| 2000 |
Chrestensen CA, Starke DW, Mieyal JJ. Acute cadmium exposure inactivates thioltransferase (Glutaredoxin), inhibits intracellular reduction of protein-glutathionyl-mixed disulfides, and initiates apoptosis. The Journal of Biological Chemistry. 275: 26556-65. PMID 10854441 DOI: 10.1074/Jbc.M004097200 |
0.43 |
|
| 2000 |
Biaglow JE, Donahue J, Tuttle S, Held K, Chrestensen C, Mieyal J. A method for measuring disulfide reduction by cultured mammalian cells: relative contributions of glutathione-dependent and glutathione-independent mechanisms. Analytical Biochemistry. 281: 77-86. PMID 10847613 DOI: 10.1006/Abio.2000.4533 |
0.342 |
|
| 1999 |
Balijepalli S, Tirumalai PS, Swamy KV, Boyd MR, Mieyal JJ, Ravindranath V. Rat brain thioltransferase: Regional distribution, immunological characterization, and localization by fluorescent in situ hybridization Journal of Neurochemistry. 72: 1170-1178. PMID 10037490 DOI: 10.1046/J.1471-4159.1999.0721170.X |
0.352 |
|
| 1999 |
Yang Y, Jao Sc, Nanduri S, Starke DW, Mieyal JJ, Qin J. Reactivity of the human thioltransferase (glutaredoxin) C7S, C25S, C78S, C82S mutant and NMR solution structure of its glutathionyl mixed disulfide intermediate reflect catalytic specificity. Biochemistry. 37: 17145-56. PMID 9860827 DOI: 10.1021/Bi9806504 |
0.382 |
|
| 1998 |
Bandyopadhyay S, Starke DW, Mieyal JJ, Gronostajski RM. Thioltransferase (glutaredoxin) reactivates the DNA-binding activity of oxidation-inactivated nuclear factor I Journal of Biological Chemistry. 273: 392-397. PMID 9417094 DOI: 10.1074/Jbc.273.1.392 |
0.414 |
|
| 1997 |
Starke DW, Chen Y, Bapna CP, Lesnefsky EJ, Mieyal JJ. Sensitivity of protein sulfhydryl repair enzymes to oxidative stress. Free Radical Biology & Medicine. 23: 373-84. PMID 9214573 DOI: 10.1016/S0891-5849(97)00009-9 |
0.432 |
|
| 1997 |
Srinivasan U, Mieyal PA, Mieyal JJ. pH profiles indicative of rate-limiting nucleophilic displacement in thioltransferase catalysis. Biochemistry. 36: 3199-206. PMID 9115997 DOI: 10.1021/Bi962017T |
0.304 |
|
| 1994 |
Mieyal JJ, Starke DW. Hydroxylation and dealkylation reactions catalyzed by hemoglobin. Methods in Enzymology. 231: 573-98. PMID 8041278 DOI: 10.1016/0076-6879(94)31040-8 |
0.4 |
|
| 1994 |
Papov VV, Gravina SA, Mieyal JJ, Biemann K. The primary structure and properties of thioltransferase (glutaredoxin) from human red blood cells. Protein Science : a Publication of the Protein Society. 3: 428-34. PMID 8019414 DOI: 10.1002/Pro.5560030307 |
0.411 |
|
| 1993 |
Gravina SA, Mieyal JJ. Thioltransferase is a specific glutathionyl mixed disulfide oxidoreductase. Biochemistry. 32: 3368-76. PMID 8461300 DOI: 10.1021/Bi00064A021 |
0.43 |
|
| 1991 |
Mieyal JJ, Starke DW, Gravina SA, Hocevar BA. Thioltransferase in human red blood cells: kinetics and equilibrium. Biochemistry. 30: 8883-91. PMID 1888746 DOI: 10.1021/Bi00100A023 |
0.424 |
|
| 1991 |
Mieyal JJ, Starke DW, Gravina SA, Dothey C, Chung JS. Thioltransferase in human red blood cells: purification and properties. Biochemistry. 30: 6088-97. PMID 1829380 DOI: 10.1021/Bi00239A002 |
0.459 |
|
| 1982 |
Blisard KS, Mieyal JJ. Role of NADPH and the NADPH-dependent methemoglobin reductase in the hydroxylase activity of human erythrocytes. Archives of Biochemistry and Biophysics. 210: 762-9. PMID 6795993 DOI: 10.1016/0003-9861(81)90243-5 |
0.351 |
|
| 1980 |
Blumer JL, Mieyal JJ. Methylcholanthrene And Tcdd-Induced Alterations In Microsomal Electron Transport In Inbred Mice Microsomes, Drug Oxidations and Chemical Carcinogenesis. 521-524. DOI: 10.1016/B978-0-12-187701-9.50099-1 |
0.305 |
|
| 1972 |
Mieyal JJ, Abeles RH. 17 Disaccharide Phosphorylases The Enzymes. 7: 515-532. DOI: 10.1016/S1874-6047(08)60461-8 |
0.342 |
|
| Show low-probability matches. |