| Year |
Citation |
Score |
| 2020 |
Chen D, Kim DJ, Shen J, Zou Z, O'Keefe RJ. Runx2 plays a central role in Osteoarthritis development. Journal of Orthopaedic Translation. 23: 132-139. PMID 32913706 DOI: 10.1016/J.Jot.2019.11.008 |
0.304 |
|
| 2019 |
Ying J, Wang P, Ding Q, Shen J, O'Keefe RJ, Chen D, Tong P, Jin H. Peripheral Blood Stem Cell Therapy Does Not Improve Outcomes of Femoral Head Osteonecrosis with Cap-shaped Separated Cartilage Defect. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. PMID 31520480 DOI: 10.1002/Jor.24471 |
0.323 |
|
| 2019 |
Feigenson M, Jonason JH, Shen J, Loiselle AE, Awad HA, O'Keefe RJ. Inhibition of the Prostaglandin EP-1 Receptor in Periosteum Progenitor Cells Enhances Osteoblast Differentiation and Fracture Repair. Annals of Biomedical Engineering. PMID 30980293 DOI: 10.1007/S10439-019-02264-7 |
0.705 |
|
| 2018 |
Wang C, Silverman RM, Shen J, O'Keefe RJ. Distinct metabolic programs induced by TGF-β1 and BMP2 in human articular chondrocytes with osteoarthritis. Journal of Orthopaedic Translation. 12: 66-73. PMID 29662780 DOI: 10.1016/J.Jot.2017.12.004 |
0.376 |
|
| 2018 |
Xu T, Wang C, Shen J, Tong P, O'Keefe R. Ablation of Dnmt3b in chondrocytes suppresses cell maturation during embryonic development. Journal of Cellular Biochemistry. PMID 29637597 DOI: 10.1002/Jcb.26775 |
0.462 |
|
| 2018 |
Yukata K, Xie C, Li TF, Brown ML, Kanchiku T, Zhang X, Awad HA, Schwarz EM, Beck CA, Jonason JH, O'Keefe RJ. Teriparatide (human PTH1-34) compensates for impaired fracture healing in COX-2 deficient mice. Bone. PMID 29408411 DOI: 10.1016/J.Bone.2018.02.001 |
0.364 |
|
| 2017 |
Ackerman JE, Best KT, O'Keefe RJ, Loiselle AE. Deletion of EP4 in S100a4-lineage cells reduces scar tissue formation during early but not later stages of tendon healing. Scientific Reports. 7: 8658. PMID 28819185 DOI: 10.1038/S41598-017-09407-7 |
0.65 |
|
| 2017 |
Feigenson M, Eliseev RA, Jonason JH, Mills BN, O'Keefe RJ. PGE2 Receptor Subtype 1 (EP1) Regulates Mesenchymal Stromal Cell Osteogenic Differentiation by Modulating Cellular Energy Metabolism. Journal of Cellular Biochemistry. PMID 28444901 DOI: 10.1002/Jcb.26092 |
0.414 |
|
| 2016 |
Zhang Y, O'Keefe RJ, Jonason JH. BMP-TAK1 (MAP3K7) Induces Adipocyte Differentiation through PPARγ Signaling. Journal of Cellular Biochemistry. PMID 27293199 DOI: 10.1002/Jcb.25626 |
0.395 |
|
| 2016 |
Orner CA, Geary MB, Hammert WC, O'Keefe RJ, Loiselle AE. Low-Dose and Short-Duration Matrix Metalloproteinase 9 Inhibition Does Not Affect Adhesion Formation during Murine Flexor Tendon Healing. Plastic and Reconstructive Surgery. 137: 545e-53e. PMID 26910699 DOI: 10.1097/01.Prs.0000475823.01907.53 |
0.638 |
|
| 2015 |
Liu Z, Ren Y, Mirando AJ, Wang C, Zuscik MJ, O'Keefe RJ, Hilton MJ. Notch Signaling in Postnatal Joint Chondrocytes, but not Subchondral Osteoblasts, is Required for Articular Cartilage and Joint Maintenance. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. PMID 26522700 DOI: 10.1016/J.Joca.2015.10.015 |
0.336 |
|
| 2015 |
Zhang Y, Sheu TJ, Hoak D, Shen J, Hilton MJ, Zuscik MJ, Jonason JH, O'Keefe RJ. CCN1 Regulates Chondrocyte Maturation and Cartilage Development. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 26363286 DOI: 10.1002/Jbmr.2712 |
0.731 |
|
| 2015 |
Geary MB, Orner CA, Bawany F, Awad HA, Hammert WC, O'Keefe RJ, Loiselle AE. Systemic EP4 Inhibition Increases Adhesion Formation in a Murine Model of Flexor Tendon Repair. Plos One. 10: e0136351. PMID 26312751 DOI: 10.1371/Journal.Pone.0136351 |
0.649 |
|
| 2015 |
Liu Z, Chen J, Mirando AJ, Wang C, Zuscik MJ, O'Keefe RJ, Hilton MJ. A dual role for NOTCH signaling in joint cartilage maintenance and osteoarthritis. Science Signaling. 8: ra71. PMID 26198357 DOI: 10.1016/J.Joca.2015.02.133 |
0.377 |
|
| 2015 |
Loiselle AE, Yukata K, Geary MB, Kondabolu S, Shi S, Jonason JH, Awad HA, O'Keefe RJ. Development of antisense oligonucleotide (ASO) technology against Tgf-β signaling to prevent scarring during flexor tendon repair. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 33: 859-66. PMID 25761254 DOI: 10.1002/Jor.22890 |
0.681 |
|
| 2015 |
Wang C, Shen J, Yukata K, Inzana JA, O'Keefe RJ, Awad HA, Hilton MJ. Transient gamma-secretase inhibition accelerates and enhances fracture repair likely via Notch signaling modulation. Bone. 73: 77-89. PMID 25527421 DOI: 10.1016/J.Bone.2014.12.007 |
0.417 |
|
| 2015 |
Zhang M, Feigenson M, Sheu TJ, Awad HA, Schwarz EM, Jonason JH, Loiselle AE, O'Keefe RJ. Loss of the PGE2 receptor EP1 enhances bone acquisition, which protects against age and ovariectomy-induced impairments in bone strength. Bone. 72: 92-100. PMID 25446888 DOI: 10.1016/J.Bone.2014.11.018 |
0.803 |
|
| 2015 |
Lee DJ, Southgate RD, Farhat YM, Loiselle AE, Hammert WC, Awad HA, O'Keefe RJ. Parathyroid hormone 1-34 enhances extracellular matrix deposition and organization during flexor tendon repair. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 33: 17-24. PMID 25266795 DOI: 10.1002/Jor.22735 |
0.7 |
|
| 2014 |
Hadjiargyrou M, O'Keefe RJ. The convergence of fracture repair and stem cells: interplay of genes, aging, environmental factors and disease. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 29: 2307-22. PMID 25264148 DOI: 10.1002/Jbmr.2373 |
0.359 |
|
| 2014 |
Beier EE, Sheu TJ, Buckley T, Yukata K, O'Keefe R, Zuscik MJ, Puzas JE. Inhibition of beta-catenin signaling by Pb leads to incomplete fracture healing. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 32: 1397-405. PMID 25044211 DOI: 10.1002/Jor.22677 |
0.782 |
|
| 2014 |
Huang C, Xue M, Chen H, Jiao J, Herschman HR, O'Keefe RJ, Zhang X. The spatiotemporal role of COX-2 in osteogenic and chondrogenic differentiation of periosteum-derived mesenchymal progenitors in fracture repair. Plos One. 9: e100079. PMID 24988184 DOI: 10.1371/Journal.Pone.0100079 |
0.453 |
|
| 2014 |
Farhat YM, Al-Maliki AA, Easa A, O'Keefe RJ, Schwarz EM, Awad HA. TGF-beta1 Suppresses Plasmin and MMP Activity in Flexor Tendon Cells via PAI-1: Implications for Scarless Flexor Tendon Repair. Journal of Cellular Physiology. PMID 24962629 DOI: 10.1002/Jcp.24707 |
0.385 |
|
| 2014 |
Yukata K, Xie C, Li TF, Takahata M, Hoak D, Kondabolu S, Zhang X, Awad HA, Schwarz EM, Beck CA, Jonason JH, O'Keefe RJ. Aging periosteal progenitor cells have reduced regenerative responsiveness to bone injury and to the anabolic actions of PTH 1-34 treatment. Bone. 62: 79-89. PMID 24530870 DOI: 10.1016/J.Bone.2014.02.002 |
0.455 |
|
| 2014 |
Shane E, Burr D, Abrahamsen B, Adler RA, Brown TD, Cheung AM, Cosman F, Curtis JR, Dell R, Dempster DW, Ebeling PR, Einhorn TA, Genant HK, Geusens P, Klaushofer K, et al. Atypical subtrochanteric and diaphyseal femoral fractures: second report of a task force of the American Society for Bone and Mineral Research. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 29: 1-23. PMID 23712442 DOI: 10.1002/Jbmr.1998 |
0.315 |
|
| 2013 |
Gao L, Sheu TJ, Dong Y, Hoak DM, Zuscik MJ, Schwarz EM, Hilton MJ, O'Keefe RJ, Jonason JH. TAK1 regulates SOX9 expression in chondrocytes and is essential for postnatal development of the growth plate and articular cartilages. Journal of Cell Science. 126: 5704-13. PMID 24144697 DOI: 10.1242/Jcs.135483 |
0.736 |
|
| 2013 |
Shen J, Li J, Wang B, Jin H, Wang M, Zhang Y, Yang Y, Im HJ, O'Keefe R, Chen D. Deletion of the transforming growth factor β receptor type II gene in articular chondrocytes leads to a progressive osteoarthritis-like phenotype in mice. Arthritis and Rheumatism. 65: 3107-19. PMID 23982761 DOI: 10.1002/Art.38122 |
0.411 |
|
| 2013 |
Mirando AJ, Liu Z, Moore T, Lang A, Kohn A, Osinski AM, O'Keefe RJ, Mooney RA, Zuscik MJ, Hilton MJ. RBP-Jκ-dependent Notch signaling is required for murine articular cartilage and joint maintenance. Arthritis and Rheumatism. 65: 2623-33. PMID 23839930 DOI: 10.1002/Art.38076 |
0.36 |
|
| 2013 |
Bonewald LF, Kiel DP, Clemens TL, Esser K, Orwoll ES, O'Keefe RJ, Fielding RA. Forum on bone and skeletal muscle interactions: summary of the proceedings of an ASBMR workshop. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 28: 1857-65. PMID 23671010 DOI: 10.1002/Jbmr.1980 |
0.328 |
|
| 2013 |
Dhillon RS, Xie C, Tyler W, Calvi LM, Awad HA, Zuscik MJ, O'Keefe RJ, Schwarz EM. PTH-enhanced structural allograft healing is associated with decreased angiopoietin-2-mediated arteriogenesis, mast cell accumulation, and fibrosis. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 28: 586-97. PMID 22991274 DOI: 10.1002/Jbmr.1765 |
0.397 |
|
| 2012 |
Loiselle AE, Frisch BJ, Wolenski M, Jacobson JA, Calvi LM, Schwarz EM, Awad HA, O'Keefe RJ. Bone marrow-derived matrix metalloproteinase-9 is associated with fibrous adhesion formation after murine flexor tendon injury. Plos One. 7: e40602. PMID 22792383 DOI: 10.1371/Journal.Pone.0040602 |
0.662 |
|
| 2012 |
Dao DY, Jonason JH, Zhang Y, Hsu W, Chen D, Hilton MJ, O'Keefe RJ. Cartilage-specific β-catenin signaling regulates chondrocyte maturation, generation of ossification centers, and perichondrial bone formation during skeletal development. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 27: 1680-94. PMID 22508079 DOI: 10.1002/Jbmr.1639 |
0.81 |
|
| 2012 |
Kim KO, Sampson ER, Maynard RD, O'Keefe RJ, Chen D, Drissi H, Rosier RN, Hilton MJ, Zuscik MJ. Ski inhibits TGF-β/phospho-Smad3 signaling and accelerates hypertrophic differentiation in chondrocytes. Journal of Cellular Biochemistry. 113: 2156-66. PMID 22461172 DOI: 10.1002/Jcb.24089 |
0.406 |
|
| 2012 |
Wang M, Tang D, Shu B, Wang B, Jin H, Hao S, Dresser KA, Shen J, Im HJ, Sampson ER, Rubery PT, Zuscik MJ, Schwarz EM, O'Keefe RJ, Wang Y, et al. Conditional activation of β-catenin signaling in mice leads to severe defects in intervertebral disc tissue. Arthritis and Rheumatism. 64: 2611-23. PMID 22422036 DOI: 10.1002/Art.34469 |
0.329 |
|
| 2012 |
Kohn A, Dong Y, Mirando AJ, Jesse AM, Honjo T, Zuscik MJ, O'Keefe RJ, Hilton MJ. Cartilage-specific RBPjκ-dependent and -independent Notch signals regulate cartilage and bone development. Development (Cambridge, England). 139: 1198-212. PMID 22354840 DOI: 10.1242/Dev.070649 |
0.341 |
|
| 2012 |
Takahata M, Schwarz EM, Chen T, O'Keefe RJ, Awad HA. Delayed short-course treatment with teriparatide (PTH(1-34)) improves femoral allograft healing by enhancing intramembranous bone formation at the graft-host junction. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 27: 26-37. PMID 21956542 DOI: 10.1002/Jbmr.518 |
0.366 |
|
| 2012 |
Xie C, Schwarz EM, Sampson ER, Dhillon RS, Li D, O'Keefe RJ, Tyler W. Unique angiogenic and vasculogenic properties of renal cell carcinoma in a xenograft model of bone metastasis are associated with high levels of vegf-a and decreased ang-1 expression. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 30: 325-33. PMID 21809376 DOI: 10.1002/Jor.21500 |
0.338 |
|
| 2012 |
Kung MH, Yukata K, O'Keefe RJ, Zuscik MJ. Aryl hydrocarbon receptor-mediated impairment of chondrogenesis and fracture healing by cigarette smoke and benzo(a)pyrene. Journal of Cellular Physiology. 227: 1062-70. PMID 21567390 DOI: 10.1002/Jcp.22819 |
0.745 |
|
| 2011 |
Shu B, Zhang M, Xie R, Wang M, Jin H, Hou W, Tang D, Harris SE, Mishina Y, O'Keefe RJ, Hilton MJ, Wang Y, Chen D. BMP2, but not BMP4, is crucial for chondrocyte proliferation and maturation during endochondral bone development. Journal of Cell Science. 124: 3428-40. PMID 21984813 DOI: 10.1242/Jcs.083659 |
0.696 |
|
| 2011 |
Sampson ER, Hilton MJ, Tian Y, Chen D, Schwarz EM, Mooney RA, Bukata SV, O'Keefe RJ, Awad H, Puzas JE, Rosier RN, Zuscik MJ. Teriparatide as a chondroregenerative therapy for injury-induced osteoarthritis. Science Translational Medicine. 3: 101ra93. PMID 21937758 DOI: 10.1126/scitranslmed.3002214 |
0.569 |
|
| 2011 |
O'Keefe RJ, Mao J. Bone tissue engineering and regeneration: from discovery to the clinic--an overview. Tissue Engineering. Part B, Reviews. 17: 389-92. PMID 21902614 DOI: 10.1089/Ten.Teb.2011.0475 |
0.328 |
|
| 2011 |
Katzel EB, Koltz PF, Tierney R, Williams JP, Awad HA, O'keefe RJ, Langstein HN. The impact of Smad3 loss of function on TGF-β signaling and radiation-induced capsular contracture. Plastic and Reconstructive Surgery. 127: 2263-9. PMID 21617460 DOI: 10.1097/Prs.0B013E3182131Bea |
0.364 |
|
| 2011 |
Sampson ER, Beck CA, Ketz J, Canary KL, Hilton MJ, Awad H, Schwarz EM, Chen D, O'Keefe RJ, Rosier RN, Zuscik MJ. Establishment of an index with increased sensitivity for assessing murine arthritis. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 29: 1145-51. PMID 21374709 DOI: 10.1002/Jor.21368 |
0.323 |
|
| 2011 |
Sampson ER, Martin BA, Morris AE, Xie C, Schwarz EM, O'Keefe RJ, Rosier RN. The orally bioavailable met inhibitor PF-2341066 inhibits osteosarcoma growth and osteolysis/matrix production in a xenograft model. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 26: 1283-94. PMID 21308771 DOI: 10.1002/Jbmr.336 |
0.363 |
|
| 2011 |
Yazici C, Takahata M, Reynolds DG, Xie C, Samulski RJ, Samulski J, Beecham EJ, Gertzman AA, Spilker M, Zhang X, O'Keefe RJ, Awad HA, Schwarz EM. Self-complementary AAV2.5-BMP2-coated femoral allografts mediated superior bone healing versus live autografts in mice with equivalent biomechanics to unfractured femur. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 1416-25. PMID 21206485 DOI: 10.1038/Mt.2010.294 |
0.4 |
|
| 2011 |
Zhang M, Ho HC, Sheu TJ, Breyer MD, Flick LM, Jonason JH, Awad HA, Schwarz EM, O'Keefe RJ. EP1(-/-) mice have enhanced osteoblast differentiation and accelerated fracture repair. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 26: 792-802. PMID 20939055 DOI: 10.1002/Jbmr.272 |
0.791 |
|
| 2011 |
Dhakal S, Chen J, McCance S, Rosier R, O'Keefe R, Constine LS. Bone density changes after radiation for extremity sarcomas: Exploring the etiology of pathologic fractures International Journal of Radiation Oncology Biology Physics. 80: 1158-1163. PMID 20888134 DOI: 10.1016/J.Ijrobp.2010.04.012 |
0.376 |
|
| 2011 |
Katzel EB, Wolenski M, Loiselle AE, Basile P, Flick LM, Langstein HN, Hilton MJ, Awad HA, Hammert WC, O'Keefe RJ. Impact of Smad3 loss of function on scarring and adhesion formation during tendon healing. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 29: 684-93. PMID 20842701 DOI: 10.1002/Jor.21235 |
0.707 |
|
| 2011 |
Jacobson JA, Yanoso-Scholl L, Reynolds DG, Dadali T, Bradica G, Bukata S, Puzas EJ, Zuscik MJ, Rosier R, O'Keefe RJ, Schwarz EM, Awad HA. Teriparatide therapy and beta-tricalcium phosphate enhance scaffold reconstruction of mouse femoral defects. Tissue Engineering. Part A. 17: 389-98. PMID 20807012 DOI: 10.1089/Ten.Tea.2010.0115 |
0.409 |
|
| 2011 |
Mirando AJ, Moore T, Lang A, Jesse AM, Kohn A, Zuscik MJ, O'Keefe RJ, Hilton MJ. 70 Rbpjk-Dependent Notch Signaling Is Required For Articular Cartilage And Joint Maintenance Osteoarthritis and Cartilage. 19. DOI: 10.1016/S1063-4584(11)60097-6 |
0.328 |
|
| 2011 |
Chen D, Wang M, Shu B, Wang B, Jin H, Schwarz EM, O'Keefe RJ. Postnatal β-catenin conditional activation mice display severe defects in intervertebral disc tissue with significant loss of growth plate cartilage and extensive osteophyte formation Bone. 48. DOI: 10.1016/J.Bone.2011.03.061 |
0.35 |
|
| 2011 |
Shane E, Burr D, Ebeling PR, Abrahamsen B, Adler RA, Brown TD, Cheung AM, Cosman F, Curtis JR, Dell R, Dempster D, Einhorn TA, Genant HK, Geusens P, Klaushofer K, et al. Atypical subtrochanteric and diaphyseal femoral fractures: Report of a task force of the American Society for Bone and Mineral Research Journal of Bone and Mineral Research. 26: 1987-1987. DOI: 10.1002/Jbmr.416 |
0.31 |
|
| 2010 |
Yanoso-Scholl L, Jacobson JA, Bradica G, Lerner AL, O'Keefe RJ, Schwarz EM, Zuscik MJ, Awad HA. Evaluation of dense polylactic acid/beta-tricalcium phosphate scaffolds for bone tissue engineering. Journal of Biomedical Materials Research. Part A. 95: 717-26. PMID 20725979 DOI: 10.1002/Jbm.A.32868 |
0.371 |
|
| 2010 |
Li TF, Gao L, Sheu TJ, Sampson ER, Flick LM, Konttinen YT, Chen D, Schwarz EM, Zuscik MJ, Jonason JH, O'Keefe RJ. Aberrant hypertrophy in Smad3-deficient murine chondrocytes is rescued by restoring transforming growth factor beta-activated kinase 1/activating transcription factor 2 signaling: a potential clinical implication for osteoarthritis. Arthritis and Rheumatism. 62: 2359-69. PMID 20506210 DOI: 10.1002/Art.27537 |
0.711 |
|
| 2010 |
Dong Y, Jesse AM, Kohn A, Gunnell LM, Honjo T, Zuscik MJ, O'Keefe RJ, Hilton MJ. RBPjkappa-dependent Notch signaling regulates mesenchymal progenitor cell proliferation and differentiation during skeletal development. Development (Cambridge, England). 137: 1461-71. PMID 20335360 DOI: 10.1242/Dev.042911 |
0.375 |
|
| 2010 |
Gunnell LM, Jonason JH, Loiselle AE, Kohn A, Schwarz EM, Hilton MJ, O'Keefe RJ. TAK1 regulates cartilage and joint development via the MAPK and BMP signaling pathways. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 25: 1784-97. PMID 20213696 DOI: 10.1002/Jbmr.79 |
0.713 |
|
| 2010 |
Dao DY, Yang X, Flick LM, Chen D, Hilton MJ, O'Keefe RJ. Axin2 regulates chondrocyte maturation and axial skeletal development. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 28: 89-95. PMID 19623616 DOI: 10.1002/Jor.20954 |
0.815 |
|
| 2010 |
O'Keefe RJ. PL6Cellular and molecular targets to enhance fracture healing and bone formation in aging Bone. 47. DOI: 10.1016/J.Bone.2010.09.050 |
0.354 |
|
| 2009 |
Yan Y, Tang D, Chen M, Huang J, Xie R, Jonason JH, Tan X, Hou W, Reynolds D, Hsu W, Harris SE, Puzas JE, Awad H, O'Keefe RJ, Boyce BF, et al. Axin2 controls bone remodeling through the beta-catenin-BMP signaling pathway in adult mice. Journal of Cell Science. 122: 3566-78. PMID 19737815 DOI: 10.1242/Jcs.051904 |
0.686 |
|
| 2009 |
Frisch BJ, Porter RL, Gigliotti BJ, Olm-Shipman AJ, Weber JM, O'Keefe RJ, Jordan CT, Calvi LM. In vivo prostaglandin E2 treatment alters the bone marrow microenvironment and preferentially expands short-term hematopoietic stem cells. Blood. 114: 4054-63. PMID 19726721 DOI: 10.1182/Blood-2009-03-205823 |
0.37 |
|
| 2009 |
Xie C, Liang B, Xue M, Lin AS, Loiselle A, Schwarz EM, Guldberg RE, O'Keefe RJ, Zhang X. Rescue of impaired fracture healing in COX-2-/- mice via activation of prostaglandin E2 receptor subtype 4. The American Journal of Pathology. 175: 772-85. PMID 19628768 DOI: 10.2353/Ajpath.2009.081099 |
0.714 |
|
| 2009 |
Wei X, Zhang X, Flick LM, Drissi H, Schwarz EM, O'Keefe RJ. Titanium particles stimulate COX-2 expression in synovial fibroblasts through an oxidative stress-induced, calpain-dependent, NF-kappaB pathway. American Journal of Physiology. Cell Physiology. 297: C310-20. PMID 19494233 DOI: 10.1152/Ajpcell.00597.2008 |
0.718 |
|
| 2009 |
Wu Q, Huang JH, Sampson ER, Kim KO, Zuscik MJ, O'Keefe RJ, Chen D, Rosier RN. Smurf2 induces degradation of GSK-3beta and upregulates beta-catenin in chondrocytes: a potential mechanism for Smurf2-induced degeneration of articular cartilage. Experimental Cell Research. 315: 2386-98. PMID 19481076 DOI: 10.1016/J.Yexcr.2009.05.019 |
0.433 |
|
| 2009 |
Tsutsumi R, Xie C, Wei X, Zhang M, Zhang X, Flick LM, Schwarz EM, O'Keefe RJ. PGE2 signaling through the EP4 receptor on fibroblasts upregulates RANKL and stimulates osteolysis. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 24: 1753-62. PMID 19419302 DOI: 10.1359/Jbmr.090412 |
0.799 |
|
| 2009 |
Taylor DK, Meganck JA, Terkhorn S, Rajani R, Naik A, O'Keefe RJ, Goldstein SA, Hankenson KD. Thrombospondin-2 influences the proportion of cartilage and bone during fracture healing. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 24: 1043-54. PMID 19123916 DOI: 10.1359/Jbmr.090101 |
0.811 |
|
| 2009 |
Loiselle AE, Bragdon GA, Jacobson JA, Hasslund S, Cortes ZE, Schwarz EM, Mitten DJ, Awad HA, O'Keefe RJ. Remodeling of murine intrasynovial tendon adhesions following injury: MMP and neotendon gene expression. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 27: 833-40. PMID 19051246 DOI: 10.1002/Jor.20769 |
0.681 |
|
| 2009 |
Clark CA, Li TF, Kim KO, Drissi H, Zuscik MJ, Zhang X, O'Keefe RJ. Prostaglandin E2 inhibits BMP signaling and delays chondrocyte maturation. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 27: 785-92. PMID 19023895 DOI: 10.1002/Jor.20805 |
0.431 |
|
| 2009 |
Naik AA, Xie C, Zuscik MJ, Kingsley P, Schwarz EM, Awad H, Guldberg R, Drissi H, Puzas JE, Boyce B, Zhang X, O'Keefe RJ. Reduced COX-2 expression in aged mice is associated with impaired fracture healing. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 24: 251-64. PMID 18847332 DOI: 10.1359/Jbmr.081002 |
0.81 |
|
| 2009 |
Zhu M, Tang D, Wu Q, Hao S, Chen M, Xie C, Rosier RN, O'Keefe RJ, Zuscik M, Chen D. Activation of beta-catenin signaling in articular chondrocytes leads to osteoarthritis-like phenotype in adult beta-catenin conditional activation mice. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 24: 12-21. PMID 18767925 DOI: 10.1359/Jbmr.080901 |
0.406 |
|
| 2008 |
Wu Q, Kim KO, Sampson ER, Chen D, Awad H, O'Brien T, Puzas JE, Drissi H, Schwarz EM, O'Keefe RJ, Zuscik MJ, Rosier RN. Induction of an osteoarthritis-like phenotype and degradation of phosphorylated Smad3 by Smurf2 in transgenic mice. Arthritis and Rheumatism. 58: 3132-44. PMID 18821706 DOI: 10.1002/Art.23946 |
0.638 |
|
| 2008 |
Xie C, Ming X, Wang Q, Schwarz EM, Guldberg RE, O'Keefe RJ, Zhang X. COX-2 from the injury milieu is critical for the initiation of periosteal progenitor cell mediated bone healing. Bone. 43: 1075-83. PMID 18773980 DOI: 10.1016/J.Bone.2008.08.109 |
0.369 |
|
| 2008 |
Zhu M, Chen M, Zuscik M, Wu Q, Wang YJ, Rosier RN, O'Keefe RJ, Chen D. Inhibition of beta-catenin signaling in articular chondrocytes results in articular cartilage destruction. Arthritis and Rheumatism. 58: 2053-64. PMID 18576323 DOI: 10.1002/Art.23614 |
0.399 |
|
| 2008 |
Kaback LA, Soung do Y, Naik A, Geneau G, Schwarz EM, Rosier RN, O'Keefe RJ, Drissi H. Teriparatide (1-34 human PTH) regulation of osterix during fracture repair. Journal of Cellular Biochemistry. 105: 219-26. PMID 18494002 DOI: 10.1002/Jcb.21816 |
0.796 |
|
| 2008 |
Tsutsumi R, Hock C, Bechtold CD, Proulx ST, Bukata SV, Ito H, Awad HA, Nakamura T, O'Keefe RJ, Schwarz EM. Differential effects of biologic versus bisphosphonate inhibition of wear debris-induced osteolysis assessed by longitudinal micro-CT. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 26: 1340-6. PMID 18404739 DOI: 10.1002/Jor.20620 |
0.376 |
|
| 2008 |
Chen M, Zhu M, Awad H, Li TF, Sheu TJ, Boyce BF, Chen D, O'Keefe RJ. Inhibition of beta-catenin signaling causes defects in postnatal cartilage development. Journal of Cell Science. 121: 1455-65. PMID 18397998 DOI: 10.1242/Jcs.020362 |
0.73 |
|
| 2008 |
Xie C, Xue M, Wang Q, Schwarz EM, O'Keefe RJ, Zhang X. Tamoxifen-inducible CreER-mediated gene targeting in periosteum via bone-graft transplantation. The Journal of Bone and Joint Surgery. American Volume. 90: 9-13. PMID 18292350 DOI: 10.2106/Jbjs.G.01212 |
0.416 |
|
| 2008 |
Basile P, Dadali T, Jacobson J, Hasslund S, Ulrich-Vinther M, Søballe K, Nishio Y, Drissi MH, Langstein HN, Mitten DJ, O'Keefe RJ, Schwarz EM, Awad HA. Freeze-dried tendon allografts as tissue-engineering scaffolds for Gdf5 gene delivery. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 466-73. PMID 18180771 DOI: 10.1038/Sj.Mt.6300395 |
0.33 |
|
| 2008 |
Wu Q, Wang M, Zuscik MJ, Chen D, O'Keefe RJ, Rosier RN. Regulation of embryonic endochondral ossification by Smurf2. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 26: 704-12. PMID 18176945 DOI: 10.1002/Jor.20563 |
0.445 |
|
| 2008 |
Wu Q, Chen D, Zuscik MJ, O'Keefe RJ, Rosier RN. Overexpression of Smurf2 stimulates endochondral ossification through upregulation of beta-catenin. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 23: 552-63. PMID 18052755 DOI: 10.1359/Jbmr.071115 |
0.397 |
|
| 2008 |
Usui M, Xing L, Drissi H, Zuscik M, O'Keefe R, Chen D, Boyce BF. Murine and chicken chondrocytes regulate osteoclastogenesis by producing RANKL in response to BMP2. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 23: 314-25. PMID 17967138 DOI: 10.1359/Jbmr.071025 |
0.458 |
|
| 2008 |
Zhu M, Chen M, Lichtler AC, O'Keefe RJ, Chen D. Tamoxifen-inducible Cre-recombination in articular chondrocytes of adult Col2a1-CreERT2 transgenic mice Osteoarthritis and Cartilage. 16: 129-130. PMID 17888690 DOI: 10.1016/J.Joca.2007.08.001 |
0.301 |
|
| 2008 |
Li D, Gromov K, Søballe K, Puzas JE, O'Keefe RJ, Awad H, Drissi H, Schwarz EM. Quantitative mouse model of implant-associated osteomyelitis and the kinetics of microbial growth, osteolysis, and humoral immunity. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 26: 96-105. PMID 17676625 DOI: 10.1002/Jor.20452 |
0.569 |
|
| 2008 |
Kaback LA, Soung do Y, Naik A, Smith N, Schwarz EM, O'Keefe RJ, Drissi H. Osterix/Sp7 regulates mesenchymal stem cell mediated endochondral ossification. Journal of Cellular Physiology. 214: 173-82. PMID 17579353 DOI: 10.1002/Jcp.21176 |
0.825 |
|
| 2008 |
Loiselle AE, O'Keefe RJ. Differential Mmp response to PGE2 during flexor tendon healing Matrix Biology. 27: 42. DOI: 10.1016/J.Matbio.2008.09.350 |
0.647 |
|
| 2007 |
Dao DY, Yang X, Chen D, Zuscik M, O'Keefe RJ. Axin1 and Axin2 are regulated by TGF- and mediate cross-talk between TGF- and Wnt signaling pathways. Annals of the New York Academy of Sciences. 1116: 82-99. PMID 18083923 DOI: 10.1196/Annals.1402.082 |
0.793 |
|
| 2007 |
Zuscik MJ, Ma L, Buckley T, Puzas JE, Drissi H, Schwarz EM, O'Keefe RJ. Lead induces chondrogenesis and alters transforming growth factor-beta and bone morphogenetic protein signaling in mesenchymal cell populations. Environmental Health Perspectives. 115: 1276-82. PMID 17805416 DOI: 10.1289/Ehp.10028 |
0.588 |
|
| 2007 |
Dong YF, Soung do Y, Chang Y, Enomoto-Iwamoto M, Paris M, O'Keefe RJ, Schwarz EM, Drissi H. Transforming growth factor-beta and Wnt signals regulate chondrocyte differentiation through Twist1 in a stage-specific manner. Molecular Endocrinology (Baltimore, Md.). 21: 2805-20. PMID 17684115 DOI: 10.1210/Me.2007-0199 |
0.428 |
|
| 2007 |
Awad HA, Zhang X, Reynolds DG, Guldberg RE, O'Keefe RJ, Schwarz EM. Recent advances in gene delivery for structural bone allografts. Tissue Engineering. 13: 1973-85. PMID 17518728 DOI: 10.1089/Ten.2006.0107 |
0.402 |
|
| 2007 |
Xie C, Reynolds D, Awad H, Rubery PT, Pelled G, Gazit D, Guldberg RE, Schwarz EM, O'Keefe RJ, Zhang X. Structural bone allograft combined with genetically engineered mesenchymal stem cells as a novel platform for bone tissue engineering. Tissue Engineering. 13: 435-45. PMID 17518596 DOI: 10.1089/Ten.2006.0182 |
0.372 |
|
| 2007 |
Soung do Y, Dong Y, Wang Y, Zuscik MJ, Schwarz EM, O'Keefe RJ, Drissi H. Runx3/AML2/Cbfa3 regulates early and late chondrocyte differentiation. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 22: 1260-70. PMID 17488194 DOI: 10.1359/Jbmr.070502 |
0.321 |
|
| 2007 |
Wang Q, Wei X, Zhu T, Zhang M, Shen R, Xing L, O'Keefe RJ, Chen D. Bone morphogenetic protein 2 activates Smad6 gene transcription through bone-specific transcription factor Runx2. The Journal of Biological Chemistry. 282: 10742-8. PMID 17215250 DOI: 10.1074/Jbc.M610997200 |
0.798 |
|
| 2007 |
Chen M, Lichtler AC, Sheu TJ, Xie C, Zhang X, O'Keefe RJ, Chen D. Generation of a transgenic mouse model with chondrocyte-specific and tamoxifen-inducible expression of Cre recombinase. Genesis (New York, N.Y. : 2000). 45: 44-50. PMID 17211877 DOI: 10.1002/Dvg.20261 |
0.71 |
|
| 2006 |
Baumhauer JF, O'Keefe RJ, Schon LC, Pinzur MS. Cytokine-induced osteoclastic bone resorption in charcot arthropathy: an immunohistochemical study. Foot & Ankle International. 27: 797-800. PMID 17054880 DOI: 10.1177/107110070602701007 |
0.391 |
|
| 2006 |
O'Keefe RJ, Tiyapatanaputi P, Xie C, Li TF, Clark C, Zuscik MJ, Chen D, Drissi H, Schwarz E, Zhang X. COX-2 has a critical role during incorporation of structural bone allografts. Annals of the New York Academy of Sciences. 1068: 532-42. PMID 16831949 DOI: 10.1196/Annals.1346.012 |
0.385 |
|
| 2006 |
Schwarz EM, Looney RJ, Drissi MH, O'Keefe RJ, Boyce BF, Xing L, Ritchlin CT. Autoimmunity and bone. Annals of the New York Academy of Sciences. 1068: 275-83. PMID 16831928 DOI: 10.1196/Annals.1346.031 |
0.386 |
|
| 2006 |
Robertson G, Xie C, Chen D, Awad H, Schwarz EM, O'Keefe RJ, Guldberg RE, Zhang X. Alteration of femoral bone morphology and density in COX-2-/- mice. Bone. 39: 767-72. PMID 16731065 DOI: 10.1016/J.Bone.2006.04.006 |
0.382 |
|
| 2006 |
Li TF, Chen D, Wu Q, Chen M, Sheu TJ, Schwarz EM, Drissi H, Zuscik M, O'Keefe RJ. Transforming growth factor-beta stimulates cyclin D1 expression through activation of beta-catenin signaling in chondrocytes. The Journal of Biological Chemistry. 281: 21296-304. PMID 16690606 DOI: 10.1074/Jbc.M600514200 |
0.689 |
|
| 2006 |
Shen R, Wang X, Drissi H, Liu F, O'Keefe RJ, Chen D. Cyclin D1-cdk4 induce runx2 ubiquitination and degradation. The Journal of Biological Chemistry. 281: 16347-53. PMID 16613857 DOI: 10.1074/Jbc.M603439200 |
0.791 |
|
| 2006 |
Dong YF, Soung do Y, Schwarz EM, O'Keefe RJ, Drissi H. Wnt induction of chondrocyte hypertrophy through the Runx2 transcription factor. Journal of Cellular Physiology. 208: 77-86. PMID 16575901 DOI: 10.1002/Jcp.20656 |
0.462 |
|
| 2006 |
Nishio Y, Dong Y, Paris M, O'Keefe RJ, Schwarz EM, Drissi H. Runx2-mediated regulation of the zinc finger Osterix/Sp7 gene. Gene. 372: 62-70. PMID 16574347 DOI: 10.1016/J.Gene.2005.12.022 |
0.391 |
|
| 2006 |
Li TF, Darowish M, Zuscik MJ, Chen D, Schwarz EM, Rosier RN, Drissi H, O'Keefe RJ. Smad3-deficient chondrocytes have enhanced BMP signaling and accelerated differentiation. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 21: 4-16. PMID 16355269 DOI: 10.1359/Jbmr.050911 |
0.446 |
|
| 2006 |
Shen R, Chen M, Wang YJ, Kaneki H, Xing L, O'keefe RJ, Chen D. Smad6 interacts with Runx2 and mediates Smad ubiquitin regulatory factor 1-induced Runx2 degradation. The Journal of Biological Chemistry. 281: 3569-76. PMID 16299379 DOI: 10.1074/Jbc.M506761200 |
0.815 |
|
| 2006 |
Eliseev RA, Schwarz EM, Zuscik MJ, O'Keefe RJ, Drissi H, Rosier RN. Smad7 mediates inhibition of Saos2 osteosarcoma cell differentiation by NFkappaB. Experimental Cell Research. 312: 40-50. PMID 16259979 DOI: 10.1016/J.Yexcr.2005.09.016 |
0.458 |
|
| 2005 |
Andela VB, Schwarz EM, O'Keefe RJ, Puzas EJ, Rosenblatt JD, Rosier RN. A genome-wide expression profile and system-level integration of nuclear factor kappa B regulated genes reveals fundamental metabolic adaptations during cell growth and survival. Febs Letters. 579: 6814-20. PMID 16330031 DOI: 10.1016/J.Febslet.2005.11.018 |
0.308 |
|
| 2005 |
Zhang X, Xie C, Lin AS, Ito H, Awad H, Lieberman JR, Rubery PT, Schwarz EM, O'Keefe RJ, Guldberg RE. Periosteal progenitor cell fate in segmental cortical bone graft transplantations: implications for functional tissue engineering. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 20: 2124-37. PMID 16294266 DOI: 10.1359/Jbmr.050806 |
0.383 |
|
| 2005 |
Eliseev RA, Zuscik MJ, Schwarz EM, O'Keefe RJ, Drissi H, Rosier RN. Increased radiation-induced apoptosis of Saos2 cells via inhibition of NFkappaB: a role for c-Jun N-terminal kinase. Journal of Cellular Biochemistry. 96: 1262-73. PMID 16167336 DOI: 10.1002/Jcb.20607 |
0.317 |
|
| 2005 |
Wang Y, Belflower RM, Dong YF, Schwarz EM, O'Keefe RJ, Drissi H. Runx1/AML1/Cbfa2 mediates onset of mesenchymal cell differentiation toward chondrogenesis. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 20: 1624-36. PMID 16059634 DOI: 10.1359/Jbmr.050516 |
0.336 |
|
| 2005 |
Koefoed M, Ito H, Gromov K, Reynolds DG, Awad HA, Rubery PT, Ulrich-Vinther M, Soballe K, Guldberg RE, Lin AS, O'Keefe RJ, Zhang X, Schwarz EM. Biological effects of rAAV-caAlk2 coating on structural allograft healing. Molecular Therapy : the Journal of the American Society of Gene Therapy. 12: 212-8. PMID 16043092 DOI: 10.1016/J.Ymthe.2005.02.026 |
0.364 |
|
| 2005 |
Dong Y, Drissi H, Chen M, Chen D, Zuscik MJ, Schwarz EM, O'Keefe RJ. Wnt-mediated regulation of chondrocyte maturation: modulation by TGF-beta. Journal of Cellular Biochemistry. 95: 1057-68. PMID 15962307 DOI: 10.1002/Jcb.20466 |
0.411 |
|
| 2005 |
Soloviev A, Schwarz EM, Darowish M, O'Keefe RJ. Sphingomyelinase mediates macrophage activation by titanium particles independent of phagocytosis: a role for free radicals, NFkappaB, and TNFalpha. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 23: 1258-65. PMID 15949909 DOI: 10.1016/J.Orthres.2005.03.019.1100230604 |
0.324 |
|
| 2005 |
Wei X, Zhang X, Zuscik MJ, Drissi MH, Schwarz EM, O'Keefe RJ. Fibroblasts express RANKL and support osteoclastogenesis in a COX-2-dependent manner after stimulation with titanium particles. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 20: 1136-48. PMID 15940366 DOI: 10.1359/Jbmr.050206 |
0.745 |
|
| 2005 |
Carmouche JJ, Puzas JE, Zhang X, Tiyapatanaputi P, Cory-Slechta DA, Gelein R, Zuscik M, Rosier RN, Boyce BF, O'Keefe RJ, Schwarz EM. Lead exposure inhibits fracture healing and is associated with increased chondrogenesis, delay in cartilage mineralization, and a decrease in osteoprogenitor frequency. Environmental Health Perspectives. 113: 749-55. PMID 15929899 DOI: 10.1289/Ehp.7596 |
0.623 |
|
| 2005 |
Gordon AH, O'Keefe RJ, Schwarz EM, Rosier RN, Puzas JE. Nuclear factor-kappaB-dependent mechanisms in breast cancer cells regulate tumor burden and osteolysis in bone. Cancer Research. 65: 3209-17. PMID 15833852 DOI: 10.1158/0008-5472.Can-04-4017 |
0.609 |
|
| 2005 |
Drissi H, Zuscik M, Rosier R, O'Keefe R. Transcriptional regulation of chondrocyte maturation: potential involvement of transcription factors in OA pathogenesis. Molecular Aspects of Medicine. 26: 169-79. PMID 15811433 DOI: 10.1016/J.Mam.2005.01.003 |
0.317 |
|
| 2005 |
Ito H, Koefoed M, Tiyapatanaputi P, Gromov K, Goater JJ, Carmouche J, Zhang X, Rubery PT, Rabinowitz J, Samulski RJ, Nakamura T, Soballe K, O'Keefe RJ, Boyce BF, Schwarz EM. Remodeling of cortical bone allografts mediated by adherent rAAV-RANKL and VEGF gene therapy. Nature Medicine. 11: 291-7. PMID 15711561 DOI: 10.1038/Nm1190 |
0.348 |
|
| 2005 |
Li TF, O'Keefe RJ, Chen D. TGF-beta signaling in chondrocytes. Frontiers in Bioscience : a Journal and Virtual Library. 10: 681-8. PMID 15569609 DOI: 10.2741/1563 |
0.31 |
|
| 2005 |
Smith N, Dong Y, Lian JB, Pratap J, Kingsley PD, van Wijnen AJ, Stein JL, Schwarz EM, O'Keefe RJ, Stein GS, Drissi MH. Overlapping expression of Runx1(Cbfa2) and Runx2(Cbfa1) transcription factors supports cooperative induction of skeletal development. Journal of Cellular Physiology. 203: 133-43. PMID 15389629 DOI: 10.1002/Jcp.20210 |
0.471 |
|
| 2004 |
Tiyapatanaputi P, Rubery PT, Carmouche J, Schwarz EM, O'Keefe RJ, Zhang X. A novel murine segmental femoral graft model. Journal of Orthopaedic Research. 22: 1254-1260. PMID 15475206 DOI: 10.1016/J.Orthres.2004.03.017 |
0.361 |
|
| 2004 |
Li TF, Zuscik MJ, Ionescu AM, Zhang X, Rosier RN, Schwarz EM, Drissi H, O'Keefe RJ. PGE2 inhibits chondrocyte differentiation through PKA and PKC signaling. Experimental Cell Research. 300: 159-69. PMID 15383323 DOI: 10.1016/J.Yexcr.2004.06.019 |
0.792 |
|
| 2004 |
Li TF, Dong Y, Ionescu AM, Rosier RN, Zuscik MJ, Schwarz EM, O'Keefe RJ, Drissi H. Parathyroid hormone-related peptide (PTHrP) inhibits Runx2 expression through the PKA signaling pathway. Experimental Cell Research. 299: 128-36. PMID 15302580 DOI: 10.1016/J.Yexcr.2004.05.025 |
0.793 |
|
| 2004 |
Ulrich-Vinther M, Duch MR, Søballe K, O'Keefe RJ, Schwarz EM, Pedersen FS. In vivo gene delivery to articular chondrocytes mediated by an adeno-associated virus vector. Journal of Orthopaedic Research. 22: 726-734. PMID 15183427 DOI: 10.1016/J.Orthres.2003.12.003 |
0.352 |
|
| 2004 |
Ferguson CM, Schwarz EM, Puzas JE, Zuscik MJ, Drissi H, O'Keefe RJ. Transforming growth factor-beta1 induced alteration of skeletal morphogenesis in vivo. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 22: 687-96. PMID 15183422 DOI: 10.1016/J.Orthres.2003.10.023 |
0.631 |
|
| 2004 |
Zhang X, Ziran N, Goater JJ, Schwarz EM, Puzas JE, Rosier RN, Zuscik M, Drissi H, O'Keefe RJ. Primary murine limb bud mesenchymal cells in long-term culture complete chondrocyte differentiation: TGF-beta delays hypertrophy and PGE2 inhibits terminal differentiation. Bone. 34: 809-17. PMID 15121012 DOI: 10.1016/J.Bone.2003.12.026 |
0.662 |
|
| 2004 |
Zuscik MJ, Baden JF, Wu Q, Sheu TJ, Schwarz EM, Drissi H, O'Keefe RJ, Puzas JE, Rosier RN. 5-azacytidine alters TGF-beta and BMP signaling and induces maturation in articular chondrocytes. Journal of Cellular Biochemistry. 92: 316-31. PMID 15108358 DOI: 10.1002/Jcb.20050 |
0.794 |
|
| 2004 |
Ionescu AM, Drissi H, Schwarz EM, Kato M, Puzas JE, McCance DJ, Rosier RN, Zuscik MJ, O'Keefe RJ. CREB Cooperates with BMP-stimulated Smad signaling to enhance transcription of the Smad6 promoter. Journal of Cellular Physiology. 198: 428-40. PMID 14755548 DOI: 10.1002/Jcp.10421 |
0.821 |
|
| 2004 |
Li P, Schwarz EM, O'Keefe RJ, Ma L, Looney RJ, Ritchlin CT, Boyce BF, Xing L. Systemic tumor necrosis factor α mediates an increase in peripheral CD11bhigh osteoclast precursors in tumor necrosis factor α–transgenic mice Arthritis & Rheumatism. 50: 265-276. PMID 14730625 DOI: 10.1002/Art.11419 |
0.372 |
|
| 2004 |
Ulrich-Vinther M, Maloney MD, Schwarz EM, Rosier R, O'Keefe RJ. Articular cartilage biology. The Journal of the American Academy of Orthopaedic Surgeons. 11: 421-30. PMID 14686827 DOI: 10.5435/00124635-200311000-00006 |
0.331 |
|
| 2004 |
Bukata SV, Gelinas J, Wei X, Rosier RN, Puzas JE, Zhang X, Schwarz EM, Song XY, Griswold DE, O'Keefe RJ. PGE2 and IL-6 production by fibroblasts in response to titanium wear debris particles is mediated through a Cox-2 dependent pathway. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 22: 6-12. PMID 14656653 DOI: 10.1016/S0736-0266(03)00153-0 |
0.769 |
|
| 2003 |
Puzas JE, O'Keefe RJ, Schwarz EM, Zhang X. Pharmacologic modulators of fracture healing: the role of cyclooxygenase inhibition. Journal of Musculoskeletal & Neuronal Interactions. 3: 308-12; discussion 3. PMID 15758306 |
0.52 |
|
| 2003 |
Li P, Schwarz EM, O'Keefe RJ, Ma L, Boyce BF, Xing L. RANK Signaling Is Not Required for TNFα‐Mediated Increase in CD11bhi Osteoclast Precursors but Is Essential for Mature Osteoclast Formation in TNFα‐Mediated Inflammatory Arthritis Journal of Bone and Mineral Research. 19: 207-213. PMID 14969390 DOI: 10.1359/Jbmr.0301233 |
0.401 |
|
| 2003 |
Drissi MH, Li X, Sheu TJ, Zuscik MJ, Schwarz EM, Puzas JE, Rosier RN, O'Keefe RJ. Runx2/Cbfa1 stimulation by retinoic acid is potentiated by BMP2 signaling through interaction with Smad1 on the collagen X promoter in chondrocytes. Journal of Cellular Biochemistry. 90: 1287-98. PMID 14635200 DOI: 10.1002/Jcb.10677 |
0.794 |
|
| 2003 |
O'Keefe RJ, Guise TA. Molecular mechanisms of bone metastasis and therapeutic implications. Clinical Orthopaedics and Related Research. S100-4. PMID 14600598 DOI: 10.1097/01.Blo.0000093847.72468.2F |
0.345 |
|
| 2003 |
Andela VB, Gordon AH, Zotalis G, Rosier RN, Goater JJ, Lewis GD, Schwarz EM, Puzas JE, O'Keefe RJ. NFkappaB: a pivotal transcription factor in prostate cancer metastasis to bone. Clinical Orthopaedics and Related Research. S75-85. PMID 14600595 DOI: 10.1097/01.Blo.0000093048.96273.Aa |
0.606 |
|
| 2003 |
Zhang D, Schwarz EM, Rosier RN, Zuscik MJ, Puzas JE, O'Keefe RJ. ALK2 functions as a BMP type I receptor and induces Indian hedgehog in chondrocytes during skeletal development. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 18: 1593-604. PMID 12968668 DOI: 10.1359/Jbmr.2003.18.9.1593 |
0.641 |
|
| 2003 |
Ballock RT, O'Keefe RJ. Physiology and pathophysiology of the growth plate. Birth Defects Research Part C-Embryo Today-Reviews. 69: 123-143. PMID 12955857 DOI: 10.1002/Bdrc.10014 |
0.354 |
|
| 2003 |
Li X, Ionescu AM, Schwarz EM, Zhang X, Drissi H, Puzas JE, Rosier RN, Zuscik MJ, O'Keefe RJ. Smad6 is induced by BMP-2 and modulates chondrocyte differentiation. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 21: 908-13. PMID 12919880 DOI: 10.1016/S0736-0266(03)00008-1 |
0.835 |
|
| 2003 |
Ionescu AM, Schwarz EM, Zuscik MJ, Drissi H, Puzas JE, Rosier RN, O'Keefe RJ. ATF-2 cooperates with Smad3 to mediate TGF-beta effects on chondrocyte maturation. Experimental Cell Research. 288: 198-207. PMID 12878171 DOI: 10.1016/S0014-4827(03)00181-2 |
0.805 |
|
| 2003 |
Flick LM, Weaver JM, Ulrich-Vinther M, Abuzzahab F, Zhang X, Dougall WC, Anderson D, O'Keefe RJ, Schwarz EM. Effects of receptor activator of NFkappaB (RANK) signaling blockade on fracture healing. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 21: 676-84. PMID 12798068 DOI: 10.1016/S0736-0266(03)00011-1 |
0.402 |
|
| 2003 |
Li X, Schwarz EM, Zuscik MJ, Rosier RN, Ionescu AM, Puzas JE, Drissi H, Sheu TJ, O'Keefe RJ. Retinoic acid stimulates chondrocyte differentiation and enhances bone morphogenetic protein effects through induction of Smad1 and Smad5. Endocrinology. 144: 2514-23. PMID 12746314 DOI: 10.1210/En.2002-220969 |
0.798 |
|
| 2003 |
Sheu TJ, Schwarz EM, Martinez DA, O'Keefe RJ, Rosier RN, Zuscik MJ, Puzas JE. A phage display technique identifies a novel regulator of cell differentiation. The Journal of Biological Chemistry. 278: 438-43. PMID 12403789 DOI: 10.1074/Jbc.M208292200 |
0.787 |
|
| 2003 |
BALLOCK RT, OʼKEEFE RJ. THE BIOLOGY OF THE GROWTH PLATE The Journal of Bone and Joint Surgery-American Volume. 85: 715-726. DOI: 10.2106/00004623-200304000-00021 |
0.367 |
|
| 2002 |
Huang W, O'Keefe RJ, Schwarz EM. Exposure to receptor-activator of NFκB ligand renders pre-osteoclasts resistant to IFN-γ by inducing terminal differentiation Arthritis Research & Therapy. 5: 1-11. PMID 12716453 DOI: 10.1186/Ar612 |
0.336 |
|
| 2002 |
Zuscik MJ, O'Keefe RJ, Gunter TE, Puzas JE, Schwarz EM, Rosier RN. Parathyroid hormone-related peptide regulation of chick tibial growth plate chondrocyte maturation requires protein kinase A. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 20: 1079-90. PMID 12382976 DOI: 10.1016/S0736-0266(02)00027-X |
0.608 |
|
| 2002 |
Andela VB, Sheu TJ, Puzas EJ, Schwarz EM, O'Keefe RJ, Rosier RN. Malignant reversion of a human osteosarcoma cell line, Saos-2, by inhibition of NFkappaB. Biochemical and Biophysical Research Communications. 297: 237-41. PMID 12237108 DOI: 10.1016/S0006-291X(02)02141-1 |
0.739 |
|
| 2002 |
Ulrich-Vinther M, Maloney MD, Goater JJ, Søballe K, Goldring MB, O'Keefe RJ, Schwarz EM. Light-activated gene transduction enhances adeno-associated virus vector-mediated gene expression in human articular chondrocytes. Arthritis & Rheumatism. 46: 2095-2104. PMID 12209514 DOI: 10.1002/Art.10433 |
0.3 |
|
| 2002 |
Ulrich-Vinther M, Carmody EE, Goater JJ, S balle K, O'Keefe RJ, Schwarz EM. Recombinant adeno-associated virus-mediated osteoprotegerin gene therapy inhibits wear debris-induced osteolysis. The Journal of Bone and Joint Surgery. American Volume. 84: 1405-12. PMID 12177271 DOI: 10.2106/00004623-200208000-00016 |
0.353 |
|
| 2002 |
Zuscik MJ, Pateder DB, Puzas JE, Schwarz EM, Rosier RN, O'Keefe RJ. Lead alters parathyroid hormone-related peptide and transforming growth factor-beta1 effects and AP-1 and NF-kappaB signaling in chondrocytes. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 20: 811-8. PMID 12168672 DOI: 10.1016/S0736-0266(02)00007-4 |
0.669 |
|
| 2002 |
Soloviev A, Schwarz EM, Kuprash DV, Nedospasov SA, Puzas JE, Rosier RN, O'Keefe RJ. The role of p105 protein in NFkappaB activation in ANA-1 murine macrophages following stimulation with titanium particles. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 20: 714-22. PMID 12168659 DOI: 10.1016/S0736-0266(01)00180-2 |
0.585 |
|
| 2002 |
Carmody EE, Schwarz EM, Puzas JE, Rosier RN, O'Keefe RJ. Viral interleukin-10 gene inhibition of inflammation, osteoclastogenesis, and bone resorption in response to titanium particles. Arthritis and Rheumatism. 46: 1298-308. PMID 12115237 DOI: 10.1002/Art.10227 |
0.609 |
|
| 2002 |
Zhang X, Schwarz EM, Young DA, Puzas JE, Rosier RN, O'Keefe RJ. Cyclooxygenase-2 regulates mesenchymal cell differentiation into the osteoblast lineage and is critically involved in bone repair. The Journal of Clinical Investigation. 109: 1405-15. PMID 12045254 DOI: 10.1172/Jci15681 |
0.619 |
|
| 2002 |
Zuscik MJ, D'Souza M, Ionescu AM, Gunter KK, Gunter TE, O'Keefe RJ, Schwarz EM, Puzas JE, Rosier RN. Growth plate chondrocyte maturation is regulated by basal intracellular calcium. Experimental Cell Research. 276: 310-9. PMID 12027460 DOI: 10.1006/Excr.2002.5527 |
0.782 |
|
| 2002 |
Sheu TJ, Schwarz EM, O'Keefe RJ, Rosier RN, Puzas JE. Use of a phage display technique to identify potential osteoblast binding sites within osteoclast lacunae. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 17: 915-22. PMID 12009023 DOI: 10.1359/Jbmr.2002.17.5.915 |
0.755 |
|
| 2002 |
Andela VB, Rosenblatt JD, Schwarz EM, Puzas EJ, O'Keefe RJ, Rosier RN. Synergism of aminobisphosphonates and farnesyl transferase inhibitors on tumor metastasis. Clinical Orthopaedics and Related Research. 228-39. PMID 11953614 DOI: 10.1097/00003086-200204000-00027 |
0.352 |
|
| 2002 |
Goater JJ, O'Keefe RJ, Rosier RN, Puzas JE, Schwarz EM. Efficacy of ex vivo OPG gene therapy in preventing wear debris induced osteolysis. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 20: 169-73. PMID 11918293 DOI: 10.1016/S0736-0266(01)00083-3 |
0.641 |
|
| 2002 |
Good CR, O'Keefe RJ, Puzas JE, Schwarz EM, Rosier RN. Immunohistochemical study of receptor activator of nuclear factor kappa-B ligand (RANK-L) in human osteolytic bone tumors. Journal of Surgical Oncology. 79: 174-9. PMID 11870668 DOI: 10.1002/Jso.10067 |
0.622 |
|
| 2002 |
Mungo DV, Zhang X, O'Keefe RJ, Rosier RN, Puzas JE, Schwarz EM. COX-1 and COX-2 expression in osteoid osteomas. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 20: 159-62. PMID 11853083 DOI: 10.1016/S0736-0266(01)00065-1 |
0.604 |
|
| 2002 |
Zhang D, Ferguson CM, O'Keefe RJ, Puzas JE, Rosier RN, Reynolds PR. A role for the BMP antagonist Chordin in endochondral ossification Journal of Bone and Mineral Research. 17: 293-300. PMID 11811560 DOI: 10.1359/Jbmr.2002.17.2.293 |
0.653 |
|
| 2002 |
Childs LM, Paschalis EP, Xing L, Dougall WC, Anderson D, Boskey AL, Puzas JE, Rosier RN, O'Keefe RJ, Boyce BF, Schwarz EM. In vivo RANK signaling blockade using the receptor activator of NF-kappaB:Fc effectively prevents and ameliorates wear debris-induced osteolysis via osteoclast depletion without inhibiting osteogenesis. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 17: 192-9. PMID 11811549 DOI: 10.1359/Jbmr.2002.17.2.192 |
0.637 |
|
| 2002 |
Puzas JE, O'Keefe RJ, Lieberman JR. The orthopaedic genome: what does the future hold and are we ready? The Journal of Bone and Joint Surgery. American Volume. 84: 133-41. PMID 11792791 DOI: 10.2106/00004623-200201000-00019 |
0.507 |
|
| 2002 |
Pateder DB, Sheu TJ, O'Keefe RJ, Puzas JE, Schwarz EM, Constine LS, Okunieff P, Rosier RN. Role of pentoxifylline in preventing radiation damage to epiphyseal growth plate chondrocytes. Radiation Research. 157: 62-8. PMID 11754643 DOI: 10.1667/0033-7587(2002)157[0062:Ropipr]2.0.Co;2 |
0.748 |
|
| 2001 |
Childs LM, Goater JJ, O'Keefe RJ, Schwarz EM. Effect of anti-tumor necrosis factor-α gene therapy on wear debris-induced osteolysis Journal of Bone and Joint Surgery - Series A. 83: 1789-1797. PMID 11741056 DOI: 10.2106/00004623-200112000-00004 |
0.362 |
|
| 2001 |
Pateder DB, Ferguson CM, Ionescu AM, Schwarz EM, Rosier RN, Puzas JE, O'Keefe RJ. PTHrP expression in chick sternal chondrocytes is regulated by TGF-beta through Smad-mediated signaling. Journal of Cellular Physiology. 188: 343-51. PMID 11473361 DOI: 10.1002/Jcp.1118 |
0.811 |
|
| 2001 |
Pollice PF, Rosier RN, Looney RJ, Puzas JE, Schwarz EM, O'Keefe RJ. Oral pentoxifylline inhibits release of tumor necrosis factor-alpha from human peripheral blood monocytes : a potential treatment for aseptic loosening of total joint components. The Journal of Bone and Joint Surgery. American Volume. 83: 1057-61. PMID 11451976 DOI: 10.2106/00004623-200107000-00012 |
0.536 |
|
| 2001 |
Pateder DB, Eliseev RA, O'Keefe RJ, Schwarz EM, Okunieff P, Constine LS, Puzas JE, Rosier RN. The role of autocrine growth factors in radiation damage to the epiphyseal growth plate. Radiation Research. 155: 847-57. PMID 11352768 DOI: 10.1667/0033-7587(2001)155[0847:Troagf]2.0.Co;2 |
0.598 |
|
| 2001 |
Grimsrud CD, Romano PR, D'Souza M, Edward Puzas J, Schwarz EM, Reynolds PR, Roiser RN, O'Keefe RJ. BMP signaling stimulates chondrocyte maturation and the expression of Indian hedgehog Journal of Orthopaedic Research. 19: 18-25. PMID 11332615 DOI: 10.1016/S0736-0266(00)00017-6 |
0.808 |
|
| 2001 |
Zhang X, Morham SG, Langenbach R, Young DA, Xing L, Boyce BF, Puzas EJ, Rosier RN, O'Keefe RJ, Schwarz EM. Evidence for a direct role of cyclo-oxygenase 2 in implant wear debris-induced osteolysis. Journal of Bone and Mineral Research. 16: 660-670. PMID 11315993 DOI: 10.1359/Jbmr.2001.16.4.660 |
0.338 |
|
| 2001 |
Childs LM, Goater JJ, O'Keefe RJ, Schwarz EM. Efficacy of etanercept for wear debris-induced osteolysis Journal of Bone and Mineral Research. 16: 338-347. PMID 11204434 DOI: 10.1359/Jbmr.2001.16.2.338 |
0.368 |
|
| 2001 |
Ionescu AM, Schwarz EM, Vinson C, Puzas JE, Rosier R, Reynolds PR, O'Keefe RJ. PTHrP Modulates Chondrocyte Differentiation through AP-1 and CREB Signaling Journal of Biological Chemistry. 276: 11639-11647. PMID 11136722 DOI: 10.1074/Jbc.M006564200 |
0.818 |
|
| 2001 |
Zhang X, Zhang Y, Schwarz EM, O'Keefe RJ. Cyclooxygenases and bone repair Current Opinion in Orthopaedics. 12: 397-402. DOI: 10.1097/00001433-200110000-00006 |
0.357 |
|
| 2000 |
Ferguson CM, Schwarz EM, Reynolds PR, Puzas JE, Rosier RN, O'Keefe RJ. Smad2 and 3 Mediate Transforming Growth Factor-β1-Induced Inhibition of Chondrocyte Maturation* *The work was supported by National Health Services Grant AR-38945 (to R.J.O.) and an Orthopaedic Research Education Foundation Award (to C.M.F.). Endocrinology. 141: 4728-4735. PMID 28200784 DOI: 10.1210/endo.141.12.7848 |
0.503 |
|
| 2000 |
Chi H, Yang X, Kingsley PD, O'Keefe RJ, Puzas JE, Rosier RN, Shears SB, Reynolds PR. Targeted deletion of Minpp1 provides new insight into the activity of multiple inositol polyphosphate phosphatase in vivo Molecular and Cellular Biology. 20: 6496-6507. PMID 10938126 DOI: 10.1128/Mcb.20.17.6496-6507.2000 |
0.61 |
|
| 2000 |
Schwarz EM, Lu AP, Goater JJ, Benz EB, Kollias G, Rosier RN, Puzas JE, O'Keefe RJ. Tumor necrosis factor-alpha/nuclear transcription factor-kappaB signaling in periprosthetic osteolysis. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 18: 472-80. PMID 10937636 DOI: 10.1002/Jor.1100180321 |
0.594 |
|
| 2000 |
Reynolds SD, Zhang D, Puzas JE, O'Keefe RJ, Rosier RN, Reynolds PR. Cloning of the chick BMP1/Tolloid cDNA and expression in skeletal tissues Gene. 248: 233-243. PMID 10806368 DOI: 10.1016/S0378-1119(00)00114-1 |
0.651 |
|
| 2000 |
Pateder DB, Rosier RN, Schwarz EM, Reynolds PR, Puzas JE, D'Souza M, O'Keefe RJ. PTHrP expression in chondrocytes, regulation by TGF-β, and interactions between epiphyseal and growth plate chondrocytes Experimental Cell Research. 256: 555-562. PMID 10772827 DOI: 10.1006/Excr.2000.4860 |
0.656 |
|
| 2000 |
O'Keefe RJ, Schwarz EM, Boyce BF. Bone metastasis: an update on mechanisms of bone resorption and therapeutic strategies Current Opinion in Orthopaedics. 11: 353-359. DOI: 10.1097/00001433-200010000-00005 |
0.359 |
|
| 2000 |
Schwarz EM, O'Keefe RJ. Breakthrough in bone: the molecular mechanism of osteoclast/osteoblast coupling revealed Current Opinion in Orthopaedics. 11: 329-335. DOI: 10.1097/00001433-200010000-00001 |
0.345 |
|
| 1999 |
Grimsrud CD, Romano PR, D'Souza M, Puzas JE, Reynolds PR, Rosier RN, O'Keefe RJ. BMP-6 is an autocrine stimulator of chondrocyte differentiation Journal of Bone and Mineral Research. 14: 475-482. PMID 10234567 DOI: 10.1359/Jbmr.1999.14.4.475 |
0.812 |
|
| 1999 |
Chi H, Tiller GE, Dasouki MJ, Romano PR, Wang J, O'Keefe RJ, Puzas JE, Rosier RN, Reynolds PR. Multiple inositol polyphosphate phosphatase: Evolution as a distinct group within the histidine phosphatase family and chromosomal localization of the human and mouse genes to chromosomes 10q23 and 19 Genomics. 56: 324-336. PMID 10087200 DOI: 10.1006/Geno.1998.5736 |
0.553 |
|
| 1999 |
Rosier RN, O'Keefe RJ, Hicks DG. The potential role of transforming growth factor beta in fracture healing. Clinical Orthopaedics and Related Research. S294-300. PMID 9917649 DOI: 10.1097/00003086-199810001-00030 |
0.412 |
|
| 1998 |
Pollice PF, Hsu J, Hicks DG, Bukata S, Rosier RN, Reynolds PR, Puzas JE, O'Keefe RJ. Interleukin-10 inhibits cytokine synthesis in monocytes stimulated by titanium particles: Evidence of an anti-inflammatory regulatory pathway Journal of Orthopaedic Research. 16: 697-704. PMID 9877394 DOI: 10.1002/Jor.1100160611 |
0.572 |
|
| 1998 |
Rapoport AP, Constine LS, Packman CH, Rosier RN, O'Keefe R, Hicks DG, Rubin SJ, Rowe JM. Treatment of Multifocal Lymphoma of Bone With Intensified Promace-Cytabom Chemotherapy and Involved Field Radiotherapy American Journal of Hematology. 58: 1-7. PMID 9590141 DOI: 10.1002/(Sici)1096-8652(199805)58:1<1::Aid-Ajh1>3.0.Co;2-X |
0.33 |
|
| 1997 |
Blaine TA, Pollice PF, Rosier RN, Reynolds PR, Puzas JE, O'Keefe RJ. Modulation of the production of cytokines in titanium-stimulated human peripheral blood monocytes by pharmacological agents. The role of cAMP- mediated signaling mechanism Journal of Bone and Joint Surgery - Series A. 79: 1519-1528. PMID 9378738 DOI: 10.2106/00004623-199710000-00009 |
0.571 |
|
| 1997 |
Rosier RN, O'Keefe RJ, Teot LA, Fox EJ, Nester TA, Puzas JE, Reynolds PR, Hicks DG. P-glycoprotein expression in cartilaginous tumors. Journal of Surgical Oncology. 65: 95-105. PMID 9209520 DOI: 10.1002/(Sici)1096-9098(199706)65:2<95::Aid-Jso5>3.0.Co;2-I |
0.528 |
|
| 1996 |
Hicks DG, O'Keefe RJ, Reynolds KJ, Cory-Slechta DA, Puzas JE, Judkins A, Rosier RN. Effects of lead on growth plate chondrocyte phenotype. Toxicology and Applied Pharmacology. 140: 164-72. PMID 8806882 DOI: 10.1006/Taap.1996.0209 |
0.639 |
|
| 1996 |
Blaine TA, Rosier RN, Puzas JE, Looney RJ, Reynolds PR, Reynolds SD, O'Keefe RJ. Increased levels of tumor necrosis factor-alpha and interleukin-6 protein and messenger RNA in human peripheral blood monocytes due to titanium particles. The Journal of Bone and Joint Surgery. American Volume. 78: 1181-92. PMID 8753710 DOI: 10.2106/00004623-199608000-00008 |
0.491 |
|
| 1996 |
Reynolds PR, Reynolds SD, O'Keefe RJ, Puzas JE, Rosier RN. Alternative splicing of a chondrocyte-specific gene. Annals of the New York Academy of Sciences. 785: 321-4. PMID 8702168 DOI: 10.1111/J.1749-6632.1996.Tb56297.X |
0.548 |
|
| 1996 |
Teot LA, O'Keefe RJ, Rosier RN, O'Connell JX, Fox EJ, Hicks DG. Extraosseous primary and recurrent giant cell tumors: transforming growth factor-beta1 and -beta2 expression may explain metaplastic bone formation. Human Pathology. 27: 625-32. PMID 8698303 DOI: 10.1016/S0046-8177(96)90389-5 |
0.394 |
|
| 1996 |
Reynolds SD, Johnston C, Leboy PS, O'Keefe RJ, Puzas JE, Rosier RN, Reynolds PR. Identification and characterization of a unique chondrocyte gene involved in transition to hypertrophy. Experimental Cell Research. 226: 197-207. PMID 8660956 DOI: 10.1006/Excr.1996.0219 |
0.592 |
|
| 1996 |
Hicks DG, Judkins AR, Sickel JZ, Rosier RN, Puzas JE, O'Keefe RJ. Granular histiocytosis of pelvic lymph nodes following total hip arthroplasty. The presence of wear debris, cytokine production, and immunologically activated macrophages. The Journal of Bone and Joint Surgery. American Volume. 78: 482-96. PMID 8609127 DOI: 10.2106/00004623-199604000-00002 |
0.476 |
|
| 1996 |
Tiller G, Dasouki M, Reynolds S, O'Keefe R, Puzas J, Rosier R, Reynolds P. Characterization of band 17, a growth plate-specific gene in chick; and mapping of its human homolog, GPTP1 Matrix Biology. 15: 184. DOI: 10.1016/S0945-053X(96)90078-5 |
0.536 |
|
| 1996 |
Hicks D, Rosier R, Constine L, Gregoritch S, O'Keefe R. 19 Radiation effects on growth factor expression and chondrocyte regulation in the epiphyseal growth plate International Journal of Radiation Oncology*Biology*Physics. 36: 168. DOI: 10.1016/S0360-3016(97)85360-6 |
0.325 |
|
| 1995 |
O'Keefe RJ, O'Donnell RJ, Temple HT, Scully SP, Mankin HJ. Giant Cell Tumor of Bone in the Foot and Ankle Foot & Ankle International. 16: 617-623. PMID 8574373 DOI: 10.1177/107110079501601007 |
0.306 |
|
| 1995 |
Hughes SS, Hicks DG, O'Keefe RJ, Hurwitz SR, Crabb ID, Krasinskas AM, Loveys L, Puzas JE, Rosier RN. Shared phenotypic expression of osteoblasts and chondrocytes in fracture callus. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 10: 533-44. PMID 7610923 DOI: 10.1002/Jbmr.5650100405 |
0.629 |
|
| 1994 |
O'Keefe RJ, Crabb ID, Puzas JE, Rosier RN. Effects of transforming growth factor-beta 1 and fibroblast growth factor on DNA synthesis in growth plate chondrocytes are enhanced by insulin-like growth factor-I. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 12: 299-310. PMID 8207583 DOI: 10.1002/jor.1100120302 |
0.537 |
|
| 1994 |
Scully SP, Mott MP, Temple HT, O'Keefe RJ, O'Donnell RJ, Mankin HJ. Late recurrence of giant-cell tumor of bone. A report of four cases. The Journal of Bone and Joint Surgery. American Volume. 76: 1231-3. PMID 8056803 DOI: 10.2106/00004623-199408000-00013 |
0.305 |
|
| 1994 |
O'Keefe RJ, Puzas JE, Loveys L, Hicks DG, Rosier RN. Analysis of type II and type X collagen synthesis in cultured growth plate chondrocytes by in situ hybridization: rapid induction of type X collagen in culture. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 9: 1713-22. PMID 7863822 DOI: 10.1002/Jbmr.5650091107 |
0.585 |
|
| 1992 |
O'Keefe RJ, Crabb ID, Puzas JE, Rosier RN. Influence of prostaglandins on DNA and matrix synthesis in growth plate chondrocytes. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 7: 397-404. PMID 1319104 DOI: 10.1002/Jbmr.5650070407 |
0.594 |
|
| 1992 |
Crabb ID, O'Keefe RJ, Puzas JE, Rosier RN. Differential effects of parathyroid hormone on chick growth plate and articular chondrocytes. Calcified Tissue International. 50: 61-6. PMID 1310882 DOI: 10.1007/Bf00297299 |
0.605 |
|
| 1990 |
Crabb ID, O'Keefe RJ, Puzas JE, Rosier RN. Synergistic effect of transforming growth factor beta and fibroblast growth factor on DNA synthesis in chick growth plate chondrocytes. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 5: 1105-12. PMID 2270774 DOI: 10.1002/Jbmr.5650051103 |
0.608 |
|
| 1990 |
O'Keefe RJ, Rosier RN, Puzas JE. Differential expression of biological effects in maturationally distinct subpopulations of growth plate chondrocytes. Connective Tissue Research. 24: 53-66. PMID 2159862 DOI: 10.3109/03008209009152422 |
0.626 |
|
| 1989 |
Rosier RN, O'Keefe RJ, Crabb ID, Puzas JE. Transforming growth factor beta: an autocrine regulator of chondrocytes. Connective Tissue Research. 20: 295-301. PMID 2612160 DOI: 10.3109/03008208909023900 |
0.628 |
|
| 1989 |
OʼKeefe RJ, Crabb ID, Puzas JE, Rosier RN. Countercurrent centrifugal elutriation. High-resolution method for the separation of growth-plate chondrocytes. The Journal of Bone & Joint Surgery. 71: 607-620. DOI: 10.2106/00004623-198971040-00017 |
0.585 |
|
| 1988 |
O'Keefe RJ, Puzas JE, Brand JS, Rosier RN. Effect of transforming growth factor-beta on DNA synthesis by growth plate chondrocytes: modulation by factors present in serum. Calcified Tissue International. 43: 352-8. PMID 3146424 DOI: 10.1007/Bf02553278 |
0.607 |
|
| Show low-probability matches. |