Tzong-Jen Sheu, Ph.D. - Publications

Affiliations: 
2002 University of Rochester, Rochester, NY 
Area:
Pathology, Animal Physiology Biology

46 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Tsai CH, Chang CY, Lin BZ, Wu YL, Wu MH, Lin LT, Huang WC, Holz JD, Sheu TJ, Lee JS, Kitsis RN, Tai PH, Lee YJ. Up-regulation of cofilin-1 in cell senescence associates with morphological change and p27 -mediated growth delay. Aging Cell. e13288. PMID 33336885 DOI: 10.1111/acel.13288  0.753
2020 Shares BH, Smith CO, Sheu TJ, Sautchuk R, Schilling K, Shum LC, Paine A, Huber A, Gira E, Brown E, Awad H, Eliseev RA. Inhibition of the mitochondrial permeability transition improves bone fracture repair. Bone. 115391. PMID 32360587 DOI: 10.1016/J.Bone.2020.115391  0.416
2020 Wang Y, Newman MR, Ackun-Farmmer M, Baranello MP, Sheu TJ, Puzas JE, Benoit DSW. Correction to Fracture-Targeted Delivery of β-Catenin Agonists Peptide-Functionalized Nanoparticles Augments Fracture Healing. Acs Nano. PMID 32208642 DOI: 10.1021/Acsnano.0C01871  0.537
2019 Lo CW, Kryvalap Y, Sheu TJ, Chang CH, Czyzyk J. Cellular proliferation in mouse and human pancreatic islets is regulated by serpin B13 inhibition and downstream targeting of E-cadherin by cathepsin L. Diabetologia. PMID 30824970 DOI: 10.1007/S00125-019-4834-0  0.331
2018 LO C, SHEU T, CZYZYK J. E-Cadherin Downregulation by Cathepsin L Plays a Role in the Proliferation of Insulin-Producing Cells following Inhibition of Serpin B13 Diabetes. 67: 2126-P. DOI: 10.2337/Db18-2126-P  0.394
2017 Newman MR, Russell SG, Schmitt CS, Marozas IA, Sheu TJ, Puzas JE, Benoit DSW. Multivalent Presentation of Peptide Targeting Groups Alters Polymer Biodistribution to Target Tissues. Biomacromolecules. PMID 29227674 DOI: 10.1021/Acs.Biomac.7B01193  0.651
2017 Wang Y, Newman MR, Ackun-Farmmer M, Baranello MP, Sheu TJ, Puzas JE, Benoit DSW. Fracture-Targeted Delivery of β-Catenin Agonists via Peptide-Functionalized Nanoparticles Augments Fracture Healing. Acs Nano. PMID 28881139 DOI: 10.1021/Acsnano.7B05103  0.623
2017 Beier EE, Sheu TJ, Resseguie EA, Takahata M, Awad HA, Cory-Slechta DA, Puzas JE. Sclerostin activity plays a key role in the negative effect of glucocorticoid signaling on osteoblast function in mice. Bone Research. 5: 17013. PMID 28529816 DOI: 10.1038/Boneres.2017.13  0.719
2016 Cheng Q, Tang W, Sheu TJ, Du Y, Gan J, Li H, Hong W, Zhu X, Xue S, Zhang X. Circulating TGF-β1 levels are negatively correlated with sclerostin levels in early postmenopausal women. Clinica Chimica Acta; International Journal of Clinical Chemistry. PMID 26826396 DOI: 10.1016/J.Cca.2016.01.025  0.505
2015 Beier EE, Holz J, Sheu TJ, Puzas JE. Elevated Lifetime Lead Exposure Impedes Osteoclast Activity and Produces an Increase in Bone Mass in Adolescent Mice. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 26518054 DOI: 10.1093/Toxsci/Kfv234  0.81
2015 Zhang Y, Sheu TJ, Hoak D, Shen J, Hilton MJ, Zuscik MJ, Jonason JH, O'Keefe RJ. CCN1 Regulates Chondrocyte Maturation and Cartilage Development. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 26363286 DOI: 10.1002/Jbmr.2712  0.635
2015 Beier EE, Sheu TJ, Dang D, Holz JD, Ubayawardena R, Babij P, Puzas JE. Heavy Metal Ion Regulation of Gene Expression: MECHANISMS BY WHICH LEAD INHIBITS OSTEOBLASTIC BONE-FORMING ACTIVITY THROUGH MODULATION OF THE Wnt/β-CATENIN SIGNALING PATHWAY. The Journal of Biological Chemistry. 290: 18216-26. PMID 25975268 DOI: 10.1074/Jbc.M114.629204  0.827
2015 Beier EE, Inzana JA, Sheu TJ, Shu L, Puzas JE, Mooney RA. Effects of Combined Exposure to Lead and High-Fat Diet on Bone Quality in Juvenile Male Mice. Environmental Health Perspectives. PMID 25861094 DOI: 10.1289/Ehp.1408581  0.629
2015 Zhang M, Feigenson M, Sheu TJ, Awad HA, Schwarz EM, Jonason JH, Loiselle AE, O'Keefe RJ. Loss of the PGE2 receptor EP1 enhances bone acquisition, which protects against age and ovariectomy-induced impairments in bone strength. Bone. 72: 92-100. PMID 25446888 DOI: 10.1016/J.Bone.2014.11.018  0.604
2014 Sheu TJ, Zhou W, Fan J, Zhou H, Zuscik MJ, Xie C, Yin G, Berk BC. Decreased BMP2 signal in GIT1 knockout mice slows bone healing. Molecular and Cellular Biochemistry. 397: 67-74. PMID 25138700 DOI: 10.1007/S11010-014-2173-5  0.466
2014 Beier EE, Sheu TJ, Buckley T, Yukata K, O'Keefe R, Zuscik MJ, Puzas JE. Inhibition of beta-catenin signaling by Pb leads to incomplete fracture healing. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 32: 1397-405. PMID 25044211 DOI: 10.1002/Jor.22677  0.727
2014 Yin G, Sheu TJ, Menon P, Pang J, Ho HC, Shi S, Xie C, Smolock E, Yan C, Zuscik MJ, Berk BC. Impaired angiogenesis during fracture healing in GPCR kinase 2 interacting protein-1 (GIT1) knock out mice. Plos One. 9: e89127. PMID 24586541 DOI: 10.1371/Journal.Pone.0089127  0.3
2014 Li TF, Yukata K, Yin G, Sheu T, Maruyama T, Jonason JH, Hsu W, Zhang X, Xiao G, Konttinen YT, Chen D, O'Keefe RJ. BMP-2 induces ATF4 phosphorylation in chondrocytes through a COX-2/PGE2 dependent signaling pathway. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. 22: 481-9. PMID 24418675 DOI: 10.1016/J.Joca.2013.12.020  0.492
2013 Gao L, Sheu TJ, Dong Y, Hoak DM, Zuscik MJ, Schwarz EM, Hilton MJ, O'Keefe RJ, Jonason JH. TAK1 regulates SOX9 expression in chondrocytes and is essential for postnatal development of the growth plate and articular cartilages. Journal of Cell Science. 126: 5704-13. PMID 24144697 DOI: 10.1242/Jcs.135483  0.641
2013 Mi M, Jin H, Wang B, Yukata K, Sheu TJ, Ke QH, Tong P, Im HJ, Xiao G, Chen D. Chondrocyte BMP2 signaling plays an essential role in bone fracture healing. Gene. 512: 211-8. PMID 23107765 DOI: 10.1016/J.Gene.2012.09.130  0.435
2013 Beier EE, Maher JR, Sheu TJ, Cory-Slechta DA, Berger AJ, Zuscik MJ, Puzas JE. Heavy metal lead exposure, osteoporotic-like phenotype in an animal model, and depression of Wnt signaling. Environmental Health Perspectives. 121: 97-104. PMID 23086611 DOI: 10.1289/Ehp.1205374  0.714
2012 Mi M, Shi S, Li T, Holz J, Lee YJ, Sheu TJ, Liao Q, Xiao T. TIMP2 deficient mice develop accelerated osteoarthritis via promotion of angiogenesis upon destabilization of the medial meniscus. Biochemical and Biophysical Research Communications. 423: 366-72. PMID 22664108 DOI: 10.1016/j.bbrc.2012.05.132  0.735
2012 Holz JD, Beier E, Sheu TJ, Ubayawardena R, Wang M, Sampson ER, Rosier RN, Zuscik M, Puzas JE. Lead induces an osteoarthritis-like phenotype in articular chondrocytes through disruption of TGF-β signaling. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 30: 1760-6. PMID 22517267 DOI: 10.1002/Jor.22117  0.783
2012 Metz-Estrella D, Jonason JH, Sheu TJ, Mroczek-Johnston RM, Puzas JE. TRIP-1: a regulator of osteoblast function. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 27: 1576-84. PMID 22460930 DOI: 10.1002/Jbmr.1611  0.723
2011 Zhang M, Ho HC, Sheu TJ, Breyer MD, Flick LM, Jonason JH, Awad HA, Schwarz EM, O'Keefe RJ. EP1(-/-) mice have enhanced osteoblast differentiation and accelerated fracture repair. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 26: 792-802. PMID 20939055 DOI: 10.1002/Jbmr.272  0.648
2010 Li TF, Gao L, Sheu TJ, Sampson ER, Flick LM, Konttinen YT, Chen D, Schwarz EM, Zuscik MJ, Jonason JH, O'Keefe RJ. Aberrant hypertrophy in Smad3-deficient murine chondrocytes is rescued by restoring transforming growth factor beta-activated kinase 1/activating transcription factor 2 signaling: a potential clinical implication for osteoarthritis. Arthritis and Rheumatism. 62: 2359-69. PMID 20506210 DOI: 10.1002/Art.27537  0.578
2010 Tang DZ, Hou W, Zhou Q, Zhang M, Holz J, Sheu TJ, Li TF, Cheng SD, Shi Q, Harris SE, Chen D, Wang YJ. Osthole stimulates osteoblast differentiation and bone formation by activation of beta-catenin-BMP signaling. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 25: 1234-45. PMID 20200936 DOI: 10.1002/Jbmr.21  0.815
2009 Matsuzawa M, Sheu TJ, Lee YJ, Chen M, Li TF, Huang CT, Holz JD, Puzas JE. Putative signaling action of amelogenin utilizes the Wnt/beta-catenin pathway. Journal of Periodontal Research. 44: 289-96. PMID 19462488 DOI: 10.1111/J.1600-0765.2008.01091.X  0.783
2009 Lee YJ, Tsai CH, Hwang JJ, Chiu SJ, Sheu TJ, Keng PC. Involvement of a p53-independent and post-transcriptional up-regulation for p21WAF/CIP1 following destabilization of the actin cytoskeleton. International Journal of Oncology. 34: 581-9. PMID 19148495 DOI: 10.3892/Ijo_00000184  0.339
2008 Chen M, Zhu M, Awad H, Li TF, Sheu TJ, Boyce BF, Chen D, O'Keefe RJ. Inhibition of beta-catenin signaling causes defects in postnatal cartilage development. Journal of Cell Science. 121: 1455-65. PMID 18397998 DOI: 10.1242/Jcs.020362  0.598
2007 Ryan EP, Holz JD, Mulcahey M, Sheu TJ, Gasiewicz TA, Puzas JE. Environmental toxicants may modulate osteoblast differentiation by a mechanism involving the aryl hydrocarbon receptor. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 22: 1571-80. PMID 17576166 DOI: 10.1359/Jbmr.070615  0.805
2007 Holz JD, Sheu TJ, Drissi H, Matsuzawa M, Zuscik MJ, Puzas JE. Environmental agents affect skeletal growth and development. Birth Defects Research. Part C, Embryo Today : Reviews. 81: 41-50. PMID 17539012 DOI: 10.1002/Bdrc.20087  0.789
2007 Chen M, Lichtler AC, Sheu TJ, Xie C, Zhang X, O'Keefe RJ, Chen D. Generation of a transgenic mouse model with chondrocyte-specific and tamoxifen-inducible expression of Cre recombinase. Genesis (New York, N.Y. : 2000). 45: 44-50. PMID 17211877 DOI: 10.1002/Dvg.20261  0.562
2007 Sun W, Puzas JE, Sheu T, Fauchet PM. Porous silicon as a cell interface for bone tissue engineering Physica Status Solidi (a). 204: 1429-1433. DOI: 10.1002/Pssa.200674377  0.581
2007 Sun W, Puzas J, Sheu T, Liu X, Fauchet P. Nano- to Microscale Porous Silicon as a Cell Interface for Bone-Tissue Engineering Advanced Materials. 19: 921-924. DOI: 10.1002/Adma.200600319  0.575
2006 Li TF, Chen D, Wu Q, Chen M, Sheu TJ, Schwarz EM, Drissi H, Zuscik M, O'Keefe RJ. Transforming growth factor-beta stimulates cyclin D1 expression through activation of beta-catenin signaling in chondrocytes. The Journal of Biological Chemistry. 281: 21296-304. PMID 16690606 DOI: 10.1074/Jbc.M600514200  0.53
2005 Lee YJ, Sheu TJ, Keng PC. Enhancement of radiosensitivity in H1299 cancer cells by actin-associated protein cofilin. Biochemical and Biophysical Research Communications. 335: 286-91. PMID 16061204 DOI: 10.1016/J.Bbrc.2005.07.073  0.307
2005 Yu HM, Jerchow B, Sheu TJ, Liu B, Costantini F, Puzas JE, Birchmeier W, Hsu W. The role of Axin2 in calvarial morphogenesis and craniosynostosis. Development (Cambridge, England). 132: 1995-2005. PMID 15790973 DOI: 10.1242/Dev.01786  0.66
2004 Zuscik MJ, Baden JF, Wu Q, Sheu TJ, Schwarz EM, Drissi H, O'Keefe RJ, Puzas JE, Rosier RN. 5-azacytidine alters TGF-beta and BMP signaling and induces maturation in articular chondrocytes. Journal of Cellular Biochemistry. 92: 316-31. PMID 15108358 DOI: 10.1002/Jcb.20050  0.704
2003 Drissi MH, Li X, Sheu TJ, Zuscik MJ, Schwarz EM, Puzas JE, Rosier RN, O'Keefe RJ. Runx2/Cbfa1 stimulation by retinoic acid is potentiated by BMP2 signaling through interaction with Smad1 on the collagen X promoter in chondrocytes. Journal of Cellular Biochemistry. 90: 1287-98. PMID 14635200 DOI: 10.1002/Jcb.10677  0.712
2003 Li X, Schwarz EM, Zuscik MJ, Rosier RN, Ionescu AM, Puzas JE, Drissi H, Sheu TJ, O'Keefe RJ. Retinoic acid stimulates chondrocyte differentiation and enhances bone morphogenetic protein effects through induction of Smad1 and Smad5. Endocrinology. 144: 2514-23. PMID 12746314 DOI: 10.1210/En.2002-220969  0.778
2003 Sheu TJ, Schwarz EM, Martinez DA, O'Keefe RJ, Rosier RN, Zuscik MJ, Puzas JE. A phage display technique identifies a novel regulator of cell differentiation. The Journal of Biological Chemistry. 278: 438-43. PMID 12403789 DOI: 10.1074/Jbc.M208292200  0.761
2002 Andela VB, Sheu TJ, Puzas EJ, Schwarz EM, O'Keefe RJ, Rosier RN. Malignant reversion of a human osteosarcoma cell line, Saos-2, by inhibition of NFkappaB. Biochemical and Biophysical Research Communications. 297: 237-41. PMID 12237108 DOI: 10.1016/S0006-291X(02)02141-1  0.669
2002 Sheu TJ, Schwarz EM, O'Keefe RJ, Rosier RN, Puzas JE. Use of a phage display technique to identify potential osteoblast binding sites within osteoclast lacunae. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 17: 915-22. PMID 12009023 DOI: 10.1359/Jbmr.2002.17.5.915  0.713
2002 Pateder DB, Sheu TJ, O'Keefe RJ, Puzas JE, Schwarz EM, Constine LS, Okunieff P, Rosier RN. Role of pentoxifylline in preventing radiation damage to epiphyseal growth plate chondrocytes. Radiation Research. 157: 62-8. PMID 11754643 DOI: 10.1667/0033-7587(2002)157[0062:Ropipr]2.0.Co;2  0.65
2001 Mollano AV, Sheu T, Puzas JE. Localization of bone formation to areas of bone resorption: osteoporosis and coupling Current Opinion in Orthopaedics. 12: 371-377. DOI: 10.1097/00001433-200110000-00002  0.663
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