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Shannon E. Telesco, Ph.D. - Publications

Affiliations: 
2011 University of Pennsylvania, Philadelphia, PA, United States 
Area:
Biomedical Engineering, Oncology, Molecular Biology
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9 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2013 Telesco SE, Vadigepalli R, Radhakrishnan R. Molecular modeling of ErbB4/HER4 kinase in the context of the HER4 signaling network helps rationalize the effects of clinically identified HER4 somatic mutations on the cell phenotype. Biotechnology Journal. 8: 1452-64. PMID 24318637 DOI: 10.1002/Biot.201300022  0.774
2012 Telesco SE, Radhakrishnan R. Structural systems biology and multiscale signaling models. Annals of Biomedical Engineering. 40: 2295-306. PMID 22539148 DOI: 10.1007/S10439-012-0576-6  0.528
2011 Telesco SE, Shih A, Liu Y, Radhakrishnan R. Investigating Molecular Mechanisms of Activation and Mutation of the HER2 Receptor Tyrosine Kinase through Computational Modeling and Simulation. Cancer Research Journal. 4: 1-35. PMID 25346782  0.744
2011 Shih AJ, Telesco SE, Radhakrishnan R. Analysis of Somatic Mutations in Cancer: Molecular Mechanisms of Activation in the ErbB Family of Receptor Tyrosine Kinases. Cancers. 3: 1195-231. PMID 21701703 DOI: 10.3390/Cancers3011195  0.784
2011 Telesco SE, Shih AJ, Jia F, Radhakrishnan R. A multiscale modeling approach to investigate molecular mechanisms of pseudokinase activation and drug resistance in the HER3/ErbB3 receptor tyrosine kinase signaling network. Molecular Biosystems. 7: 2066-80. PMID 21509365 DOI: 10.1039/C0Mb00345J  0.781
2011 Shih AJ, Telesco SE, Choi SH, Lemmon MA, Radhakrishnan R. Molecular dynamics analysis of conserved hydrophobic and hydrophilic bond-interaction networks in ErbB family kinases. The Biochemical Journal. 436: 241-51. PMID 21426301 DOI: 10.1042/Bj20101791  0.786
2010 Shi F, Telesco SE, Liu Y, Radhakrishnan R, Lemmon MA. ErbB3/HER3 intracellular domain is competent to bind ATP and catalyze autophosphorylation. Proceedings of the National Academy of Sciences of the United States of America. 107: 7692-7. PMID 20351256 DOI: 10.1073/Pnas.1002753107  0.772
2010 Shih AJ, Telesco SE, Choi SH, Lemmon MA, Radhakrishnan R. Conserved Hydrophobic and Hydrophilic Bond Interaction Networks in ErbB Family Kinases Biophysical Journal. 98: 445a. DOI: 10.1016/J.Bpj.2009.12.2417  0.775
2009 Telesco SE, Radhakrishnan R. Atomistic insights into regulatory mechanisms of the HER2 tyrosine kinase domain: a molecular dynamics study. Biophysical Journal. 96: 2321-34. PMID 19289058 DOI: 10.1016/J.Bpj.2008.12.3912  0.809
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