Claire M. Doerschuk - Publications

Affiliations: 
Case Western Reserve University, Cleveland Heights, OH, United States 
Area:
Biomedical Engineering

48/168 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Hagan RS, Gomez JC, Torres-Castillo J, Martin JR, Doerschuk CM. TBK1 is Required for Host Defense Functions Distinct from Type I IFN Expression and Myeloid Cell Recruitment in Murine pneumonia. American Journal of Respiratory Cell and Molecular Biology. PMID 35358404 DOI: 10.1165/rcmb.2020-0311OC  0.314
2019 Li Y, Wittchen ES, Monaghan-Benson E, Hahn C, Earp HS, Doerschuk CM, Burridge K. The role of endothelial MERTK during the inflammatory response in lungs. Plos One. 14: e0225051. PMID 31805065 DOI: 10.1371/Journal.Pone.0225051  0.414
2011 Wang JG, Williams JC, Davis BK, Jacobson K, Doerschuk CM, Ting JP, Mackman N. Monocytic microparticles activate endothelial cells in an IL-1β-dependent manner. Blood. 118: 2366-74. PMID 21700772 DOI: 10.1182/Blood-2011-01-330878  0.324
2010 Kang I, Wang Q, Eppell SJ, Marchant RE, Doerschuk CM. Effect of neutrophil adhesion on the mechanical properties of lung microvascular endothelial cells. American Journal of Respiratory Cell and Molecular Biology. 43: 591-8. PMID 20023207 DOI: 10.1165/Rcmb.2006-0381Oc  0.672
2008 Gomez JC, Soltys J, Okano K, Dinauer MC, Doerschuk CM. The role of Rac2 in regulating neutrophil production in the bone marrow and circulating neutrophil counts. The American Journal of Pathology. 173: 507-17. PMID 18583316 DOI: 10.2353/Ajpath.2008.071059  0.341
2008 Kang I, Panneerselvam D, Panoskaltsis VP, Eppell SJ, Marchant RE, Doerschuk CM. Changes in the hyperelastic properties of endothelial cells induced by tumor necrosis factor-alpha. Biophysical Journal. 94: 3273-85. PMID 18199670 DOI: 10.1529/Biophysj.106.099333  0.636
2007 Vachon E, Martin R, Kwok V, Cherepanov V, Chow CW, Doerschuk CM, Plumb J, Grinstein S, Downey GP. CD44-mediated phagocytosis induces inside-out activation of complement receptor-3 in murine macrophages. Blood. 110: 4492-502. PMID 17827392 DOI: 10.1182/Blood-2007-02-076539  0.304
2007 Doerschuk CM. Pulmonary alveolar proteinosis--is host defense awry? The New England Journal of Medicine. 356: 547-9. PMID 17287475 DOI: 10.1056/Nejmp068259  0.361
2007 Drawz SM, Doerschuk C. The role of CD44 in inflammatory mediator expression by neutrophils, macrophages, and endothelial cells in E.coli pneumonia The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A406-A  0.408
2006 Yoshida K, Kondo R, Wang Q, Doerschuk CM. Neutrophil cytoskeletal rearrangements during capillary sequestration in bacterial pneumonia in rats. American Journal of Respiratory and Critical Care Medicine. 174: 689-98. PMID 16741152 DOI: 10.1164/rccm.200502-276OC  0.306
2006 Koss M, Pfeiffer GR, Wang Y, Thomas ST, Yerukhimovich M, Gaarde WA, Doerschuk CM, Wang Q. Ezrin/radixin/moesin proteins are phosphorylated by TNF-alpha and modulate permeability increases in human pulmonary microvascular endothelial cells. Journal of Immunology (Baltimore, Md. : 1950). 176: 1218-27. PMID 16394012 DOI: 10.4049/Jimmunol.176.2.1218  0.373
2005 Doerschuk CM. Circulating endothelial progenitor cells in pulmonary inflammation. Thorax. 60: 362-4. PMID 15860709 DOI: 10.1136/thx.2004.037796  0.393
2005 Tasaka S, Koh H, Yamada W, Shimizu M, Ogawa Y, Hasegawa N, Yamaguchi K, Ishii Y, Richer SE, Doerschuk CM, Ishizaka A. Attenuation of endotoxin-induced acute lung injury by the Rho-associated kinase inhibitor, Y-27632. American Journal of Respiratory Cell and Molecular Biology. 32: 504-10. PMID 15778497 DOI: 10.1165/rcmb.2004-0009OC  0.384
2005 Wang Q, Yerukhimovich M, Gaarde WA, Popoff IJ, Doerschuk CM. MKK3 and -6-dependent activation of p38alpha MAP kinase is required for cytoskeletal changes in pulmonary microvascular endothelial cells induced by ICAM-1 ligation. American Journal of Physiology. Lung Cellular and Molecular Physiology. 288: L359-69. PMID 15516490 DOI: 10.1152/Ajplung.00292.2004  0.347
2005 Wang Q, Kang I, Doerschuk CM. Chapter 11 Interaction of pulmonary endothelial cells with blood elements Advances in Molecular and Cell Biology. 35: 311-334. DOI: 10.1016/S1569-2558(05)35011-9  0.663
2004 Wang Q, Doerschuk CM, Mizgerd JP. Neutrophils in innate immunity. Seminars in Respiratory and Critical Care Medicine. 25: 33-41. PMID 16088447 DOI: 10.1055/S-2004-822303  0.366
2004 Doerschuk CM. NO and neutrophils during sepsis: NO says "yes" to sequestration but "no" to migration. American Journal of Respiratory and Critical Care Medicine. 170: 205-6. PMID 15280167 DOI: 10.1164/Rccm.2405005  0.388
2003 Tasaka S, Qin L, Saijo A, Albelda SM, DeLisser HM, Doerschuk CM. Platelet endothelial cell adhesion molecule-1 in neutrophil emigration during acute bacterial pneumonia in mice and rats. American Journal of Respiratory and Critical Care Medicine. 167: 164-70. PMID 12524254 DOI: 10.1164/rccm.2202011  0.314
2002 Wang Q, Teder P, Judd NP, Noble PW, Doerschuk CM. CD44 deficiency leads to enhanced neutrophil migration and lung injury in Escherichia coli pneumonia in mice. The American Journal of Pathology. 161: 2219-28. PMID 12466136 DOI: 10.1016/S0002-9440(10)64498-7  0.373
2002 Kozower BD, Kanaan SA, Tagawa T, Suda T, Grapperhaus K, Daddi N, Crouch EC, Doerschuk CM, Patterson GA. Intramuscular gene transfer of interleukin-10 reduces neutrophil recruitment and ameliorates lung graft ischemia-reperfusion injury. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2: 837-42. PMID 12392289 DOI: 10.1034/J.1600-6143.2002.20905.X  0.312
2002 Bathe M, Shirai A, Doerschuk CM, Kamm RD. Neutrophil transit times through pulmonary capillaries: the effects of capillary geometry and fMLP-stimulation. Biophysical Journal. 83: 1917-33. PMID 12324412 DOI: 10.1016/S0006-3495(02)73955-6  0.405
2002 Wang Q, Pfeiffer GR, Stevens T, Doerschuk CM. Lung microvascular and arterial endothelial cells differ in their responses to intercellular adhesion molecule-1 ligation. American Journal of Respiratory and Critical Care Medicine. 166: 872-7. PMID 12231500 DOI: 10.1164/rccm.2201007  0.397
2002 Wang Q, Doerschuk CM. The signaling pathways induced by neutrophil-endothelial cell adhesion. Antioxidants & Redox Signaling. 4: 39-47. PMID 11970842 DOI: 10.1089/152308602753625843  0.364
2002 Saito H, Lai J, Rogers R, Doerschuk CM. Mechanical properties of rat bone marrow and circulating neutrophils and their responses to inflammatory mediators. Blood. 99: 2207-13. PMID 11877299  0.34
2001 Wang Q, Doerschuk CM. The p38 mitogen-activated protein kinase mediates cytoskeletal remodeling in pulmonary microvascular endothelial cells upon intracellular adhesion molecule-1 ligation. Journal of Immunology (Baltimore, Md. : 1950). 166: 6877-84. PMID 11359848 DOI: 10.4049/JIMMUNOL.166.11.6877  0.33
2001 Wang Q, Chiang ET, Lim M, Lai J, Rogers R, Janmey PA, Shepro D, Doerschuk CM. Changes in the biomechanical properties of neutrophils and endothelial cells during adhesion Blood. 97: 660-668. PMID 11157482 DOI: 10.1182/Blood.V97.3.660  0.405
2001 DOERSCHUK CM. Mechanisms of Leukocyte Sequestration in Inflamed Lungs Microcirculation. 8: 71-88. DOI: 10.1111/J.1549-8719.2001.Tb00159.X  0.549
2000 Doerschuk CM. Leukocyte trafficking in alveoli and airway passages. Respiratory Research. 1: 136-40. PMID 11667977 DOI: 10.1186/Rr24  0.414
2000 Doerschuk CM, Tasaka S, Wang Q. CD11/CD18-dependent and -independent neutrophil emigration in the lungs: how do neutrophils know which route to take? American Journal of Respiratory Cell and Molecular Biology. 23: 133-6. PMID 10919976 DOI: 10.1165/Ajrcmb.23.2.F193  0.361
2000 Wang Q, Doerschuk CM. Neutrophil-induced changes in the biomechanical properties of endothelial cells: roles of ICAM-1 and reactive oxygen species. Journal of Immunology (Baltimore, Md. : 1950). 164: 6487-94. PMID 10843706 DOI: 10.4049/JIMMUNOL.164.12.6487  0.352
1998 Kubo H, Graham L, Doyle NA, Quinlan WM, Hogg JC, Doerschuk CM. Complement Fragment-Induced Release of Neutrophils From Bone Marrow and Sequestration Within Pulmonary Capillaries in Rabbits Blood. 92: 283-290. DOI: 10.1182/blood.V92.1.283.413a04_283_290  0.353
1996 Salva PS, Doyle NA, Graham L, Eigen H, Doerschuk CM. TNF-alpha, IL-8, soluble ICAM-1, and neutrophils in sputum of cystic fibrosis patients. Pediatric Pulmonology. 21: 11-9. PMID 8776260 DOI: 10.1002/(Sici)1099-0496(199601)21:1<11::Aid-Ppul2>3.0.Co;2-T  0.327
1996 Mizgerd JP, Meek BB, Kutkoski GJ, Bullard DC, Beaudet AL, Doerschuk CM. Selectins and neutrophil traffic: margination and Streptococcus pneumoniae-induced emigration in murine lungs. The Journal of Experimental Medicine. 184: 639-45. PMID 8760817 DOI: 10.1084/Jem.184.2.639  0.328
1995 Doerschuk CM, Markos J, Coxson HO, English D, Hogg JC. Quantitation of neutrophil migration in acute bacterial pneumonia in rabbits. Journal of Applied Physiology (Bethesda, Md. : 1985). 77: 2593-9. PMID 7896596 DOI: 10.1152/jappl.1994.77.6.2593  0.33
1995 Andres DW, Kutkoski GJ, Quinlan WM, Doyle NA, Doerschuk CM. Effect of pentoxifylline on changes in neutrophil sequestration and emigration in the lungs. The American Journal of Physiology. 268: L27-32. PMID 7840225 DOI: 10.1152/Ajplung.1995.268.1.L27  0.492
1995 Wiebke JL, Quinlan WM, Doyle NA, Sligh JE, Smith CW, Doerschuk CM. Lymphocyte accumulation during Pseudomonas aeruginosa-induced pneumonia in rodents does not require CD11a and intercellular adhesion molecule-1. American Journal of Respiratory Cell and Molecular Biology. 12: 513-9. PMID 7742015 DOI: 10.1165/Ajrcmb.12.5.7742015  0.334
1995 Bullard DC, Qin L, Lorenzo I, Quinlin WM, Doyle NA, Bosse R, Vestweber D, Doerschuk CM, Beaudet AL. P-selectin/ICAM-1 double mutant mice: acute emigration of neutrophils into the peritoneum is completely absent but is normal into pulmonary alveoli. The Journal of Clinical Investigation. 95: 1782-8. PMID 7535798 DOI: 10.1172/JCI117856  0.323
1994 Mueller GA, Quinlan WM, Doyle NA, Doerschuk CM. The role of cytoskeletal proteins in neutrophil emigration during pneumonia in rabbits. American Journal of Respiratory and Critical Care Medicine. 150: 455-61. PMID 8049829 DOI: 10.1164/Ajrccm.150.2.8049829  0.474
1994 Wiggs BR, English D, Quinlan WM, Doyle NA, Hogg JC, Doerschuk CM. Contributions of capillary pathway size and neutrophil deformability to neutrophil transit through rabbit lungs. Journal of Applied Physiology (Bethesda, Md. : 1985). 77: 463-70. PMID 7961270 DOI: 10.1152/Jappl.1994.77.1.463  0.416
1994 Andreoli SP, Mallett C, Williams K, McAteer JA, Rothlein R, Doerschuk CM. Mechanisms of polymorphonuclear leukocyte mediated peritoneal mesothelial cell injury Kidney International. 46: 1100-1109. PMID 7861704 DOI: 10.1038/Ki.1994.372  0.37
1993 Doerschuk CM, Beyers N, Coxson HO, Wiggs B, Hogg JC. Comparison of neutrophil and capillary diameters and their relation to neutrophil sequestration in the lung. Journal of Applied Physiology (Bethesda, Md. : 1985). 74: 3040-5. PMID 8366005 DOI: 10.1152/jappl.1993.74.6.3040  0.351
1993 Markos J, Doerschuk CM, English D, Wiggs BR, Hogg JC. Effect of positive end-expiratory pressure on leukocyte transit in rabbit lungs. Journal of Applied Physiology (Bethesda, Md. : 1985). 74: 2627-33. PMID 8365962 DOI: 10.1152/Jappl.1993.74.6.2627  0.372
1992 Ohgami M, Doerschuk CM, Gie RP, English D, Hogg JC. Late effects of endotoxin on the accumulation and function of monocytes in rabbit lungs. The American Review of Respiratory Disease. 146: 190-5. PMID 1626802 DOI: 10.1164/ajrccm/146.1.190  0.315
1992 Doerschuk CM. The role of CD18-mediated adhesion in neutrophil sequestration induced by infusion of activated plasma in rabbits. American Journal of Respiratory Cell and Molecular Biology. 7: 140-8. PMID 1353974 DOI: 10.1165/ajrcmb/7.2.140  0.339
1991 Ohgami M, Doerschuk CM, Gie RP, English D, Hogg JC. Monocyte kinetics in rabbits. Journal of Applied Physiology (Bethesda, Md. : 1985). 70: 152-7. PMID 2010371 DOI: 10.1152/jappl.1991.70.1.152  0.323
1991 Picker LJ, Warnock RA, Burns AR, Doerschuk CM, Berg EL, Butcher EC. The neutrophil selectin LECAM-1 presents carbohydrate ligands to the vascular selectins ELAM-1 and GMP-140. Cell. 66: 921-33. PMID 1716182 DOI: 10.1016/0092-8674(91)90438-5  0.325
1990 Doerschuk CM, Downey GP, Doherty DE, English D, Gie RP, Ohgami M, Worthen GS, Henson PM, Hogg JC. Leukocyte and platelet margination within microvasculature of rabbit lungs. Journal of Applied Physiology (Bethesda, Md. : 1985). 68: 1956-61. PMID 2361897 DOI: 10.1152/jappl.1990.68.5.1956  0.343
1988 Doerschuk CM, Allard MF, Martin BA, MacKenzie A, Autor AP, Hogg JC. Marginated pool of neutrophils in rabbit lungs. Journal of Applied Physiology (Bethesda, Md. : 1985). 63: 1806-15. PMID 3693216 DOI: 10.1152/jappl.1987.63.5.1806  0.32
Low-probability matches (unlikely to be authored by this person)
1989 Doerschuk CM, Allard MF, Hogg JC. Neutrophil kinetics in rabbits during infusion of zymosan-activated plasma. Journal of Applied Physiology (Bethesda, Md. : 1985). 67: 88-95. PMID 2759981 DOI: 10.1152/jappl.1989.67.1.88  0.297
1995 Hogg JC, Coxson HO, Brumwell ML, Beyers N, Doerschuk CM, MacNee W, Wiggs BR. Erythrocyte and polymorphonuclear cell transit time and concentration in human pulmonary capillaries. Journal of Applied Physiology (Bethesda, Md. : 1985). 77: 1795-800. PMID 7836202 DOI: 10.1152/Jappl.1994.77.4.1795  0.292
1995 Pavalko FM, Walker DM, Graham L, Goheen M, Doerschuk CM, Kansas GS. The cytoplasmic domain of L-selectin interacts with cytoskeletal proteins via alpha-actinin: receptor positioning in microvilli does not require interaction with alpha-actinin. The Journal of Cell Biology. 129: 1155-64. PMID 7538138 DOI: 10.1083/Jcb.129.4.1155  0.289
1989 Ohgami M, Doerschuk CM, English D, Dodek PM, Hogg JC. Kinetics of radiolabeled neutrophils in swine. Journal of Applied Physiology (Bethesda, Md. : 1985). 66: 1881-5. PMID 2732181 DOI: 10.1152/jappl.1989.66.4.1881  0.288
2020 Mock JR, Dial CF, Tune MK, Gilmore RC, O'Neal WK, Dang H, Doerschuk CM. Impact of Tregs on AT2 Cell Transcriptomes During Resolution of ALI and Contributions of IFN-γ. American Journal of Respiratory Cell and Molecular Biology. PMID 32543909 DOI: 10.1165/rcmb.2019-0399OC  0.287
2015 Saini Y, Wilkinson KJ, Terrell KA, Burns KA, Livraghi-Butrico A, Doerschuk CM, O'Neal WK, Boucher RC. Neonatal Pulmonary Macrophage Depletion Coupled to Defective Mucus Clearance Increases Susceptibility to Pneumonia and Alters Pulmonary Immune Responses. American Journal of Respiratory Cell and Molecular Biology. PMID 26121027 DOI: 10.1165/Rcmb.2014-0111Oc  0.283
1991 Dodek PM, Paré PD, Minshall DK, Wiggs BR, Doerschuk CM, Baile EM. Direct injury to the bronchial vasculature in anesthetized sheep. Journal of Applied Physiology (Bethesda, Md. : 1985). 70: 2072-9. PMID 1864789 DOI: 10.1152/jappl.1991.70.5.2072  0.28
1995 Pollock JD, Williams DA, Gifford MA, Li LL, Du X, Fisherman J, Orkin SH, Doerschuk CM, Dinauer MC. Mouse model of X-linked chronic granulomatous disease, an inherited defect in phagocyte superoxide production. Nature Genetics. 9: 202-9. PMID 7719350 DOI: 10.1038/Ng0295-202  0.28
1993 Winn RK, Mileski WJ, Kovach NL, Doerschuk CM, Rice CL, Harlan JM. Role of protein synthesis and CD11/CD18 adhesion complex in neutrophil emigration into the lung. Experimental Lung Research. 19: 221-35. PMID 8467763 DOI: 10.3109/01902149309031721  0.279
1999 Bateman ST, Saito H, Lilly CM, Doerschuk CM. MECHANICAL PROPERTIES OF NEUTROPHILS ENTERING AND EXITING THE LUNGS IN ARDS PATIENTS Critical Care Medicine. 27: A128. DOI: 10.1097/00003246-199912001-00356  0.279
1995 Gebb SA, Graham JA, Hanger CC, Godbey PS, Capen RL, Doerschuk CM, Wagner WW. Sites of leukocyte sequestration in the pulmonary microcirculation Journal of Applied Physiology. 79: 493-497. PMID 7592208 DOI: 10.1152/Jappl.1995.79.2.493  0.278
2018 Hagan RS, Torres-Castillo J, Doerschuk CM. Myeloid TBK1 Signaling Contributes to the Immune Response to Influenza. American Journal of Respiratory Cell and Molecular Biology. PMID 30290124 DOI: 10.1165/rcmb.2018-0122OC  0.276
2015 Gomez JC, Yamada M, Martin JR, Dang H, Brickey WJ, Bergmeier W, Dinauer MC, Doerschuk CM. Mechanisms of interferon-γ production by neutrophils and its function during Streptococcus pneumoniae pneumonia. American Journal of Respiratory Cell and Molecular Biology. 52: 349-64. PMID 25100610 DOI: 10.1165/Rcmb.2013-0316Oc  0.276
2020 Norton DL, Ceppe A, Tune MK, McCravy M, Devlin T, Drummond MB, Carson SS, Vincent BG, Hagan RS, Dang H, Doerschuk CM, Mock JR. Bronchoalveolar Tregs are associated with duration of mechanical ventilation in acute respiratory distress syndrome. Journal of Translational Medicine. 18: 427. PMID 33176790 DOI: 10.1186/s12967-020-02595-3  0.273
2018 Immormino RM, Lauzier DC, Nakano H, Hernandez ML, Alexis NE, Ghio AL, Tilley SL, Doerschuk CM, Peden DB, Cook DN, Moran TP. Neuropilin-2 regulates airway inflammatory responses to inhaled lipopolysaccharide. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 29671604 DOI: 10.1152/Ajplung.00067.2018  0.272
2021 Gomez JC, Doerschuk CM. Neutrophil DREAM come true: The not-so-impossible quest for mechanisms of neutrophil function and heterogeneity. The Journal of Experimental Medicine. 219. PMID 34910084 DOI: 10.1084/jem.20212141  0.272
1992 Inano H, English D, Doerschuk CM. Effect of zymosan-activated plasma on the deformability of rabbit polymorphonuclear leukocytes Journal of Applied Physiology. 73: 1370-1376. PMID 1447082 DOI: 10.1152/jappl.1992.73.4.1370  0.271
1998 Motosugi H, Quinlan WM, Bree M, Doerschuk CM. Role of CD11b in focal acid-induced pneumonia and contralateral lung injury in rats. American Journal of Respiratory and Critical Care Medicine. 157: 192-8. PMID 9445299 DOI: 10.1164/ajrccm.157.1.9602095  0.268
1997 Doyle NA, Bhagwan SD, Meek BB, Kutkoski GJ, Steeber DA, Tedder TF, Doerschuk CM. Neutrophil margination, sequestration, and emigration in the lungs of L-selectin-deficient mice. The Journal of Clinical Investigation. 99: 526-33. PMID 9022088 DOI: 10.1172/JCI119189  0.266
2019 Vigeland CL, Beggs HS, Collins SL, Chan-Li Y, Powell JD, Doerschuk CM, Horton MR. Inhibition of glutamine metabolism accelerates resolution of acute lung injury. Physiological Reports. 7: e14019. PMID 30821123 DOI: 10.14814/phy2.14019  0.266
2017 Dial CF, Tune MK, Doerschuk CM, Mock JR. Foxp3(+) Regulatory T Cell Expression of Keratinocyte Growth Factor Enhances Lung Epithelial Proliferation. American Journal of Respiratory Cell and Molecular Biology. PMID 28296468 DOI: 10.1165/rcmb.2017-0019OC  0.265
2000 Mizgerd JP, Peschon JJ, Doerschuk CM. Roles of tumor necrosis factor receptor signaling during murine Escherichia coli pneumonia. American Journal of Respiratory Cell and Molecular Biology. 22: 85-91. PMID 10615069 DOI: 10.1165/Ajrcmb.22.1.3733  0.264
2002 Tasaka S, Richer SE, Mizgerd JP, Doerschuk CM. Very late antigen-4 in CD18-independent neutrophil emigration during acute bacterial pneumonia in mice. American Journal of Respiratory and Critical Care Medicine. 166: 53-60. PMID 12091171 DOI: 10.1164/Rccm.2105034  0.263
1991 Gie RP, Doerschuk CM, English D, Coxson HO, Hogg JC. Neutrophil-associated lung injury after the infusion of activated plasma. Journal of Applied Physiology (Bethesda, Md. : 1985). 70: 2471-8. PMID 1885440 DOI: 10.1152/jappl.1991.70.6.2471  0.262
2004 Zhou Y, Doerschuk CM, Anderson JM, Marchant RE. Biomaterial surface-dependent neutrophil mobility. Journal of Biomedical Materials Research. Part A. 69: 611-20. PMID 15162402 DOI: 10.1002/Jbm.A.30015  0.259
2011 Williams JC, Lee RD, Doerschuk CM, Mackman N. Effect of PAR-2 Deficiency in Mice on KC Expression after Intratracheal LPS Administration. Journal of Signal Transduction. 2011: 415195. PMID 22175012 DOI: 10.1155/2011/415195  0.259
1998 Haley KJ, Sunday ME, Wiggs BR, Kozakewich HP, Reilly JJ, Mentzer SJ, Sugarbaker DJ, Doerschuk CM, Drazen JM. Inflammatory cell distribution within and along asthmatic airways. American Journal of Respiratory and Critical Care Medicine. 158: 565-72. PMID 9700136 DOI: 10.1164/ajrccm.158.2.9705036  0.258
2022 LeMaster WB, Quibrera PM, Couper D, Tashkin DP, Bleecker ER, Doerschuk CM, Ortega VE, Cooper C, Han MK, Woodruff PG, O'Neal WK, Anderson WH, Alexis NE, Bowler RP, Barr RG, et al. Clinical implications of low absolute blood eosinophil count in the SPIROMICS COPD cohort. Chest. PMID 36343688 DOI: 10.1016/j.chest.2022.10.029  0.258
2007 Liu J, Strainic MG, Heinzel FP, Pearlman E, Doerschuk C, Lin F, Medof ME. Toll-like receptor engagement augments T cell responses by increasing local complement production by APCs Molecular Immunology. 44: 208. DOI: 10.1016/J.Molimm.2006.07.143  0.257
2013 Samson T, van Buul JD, Kroon J, Welch C, Bakker EN, Matlung HL, van den Berg TK, Sharek L, Doerschuk C, Hahn K, Burridge K. The guanine-nucleotide exchange factor SGEF plays a crucial role in the formation of atherosclerosis. Plos One. 8: e55202. PMID 23372835 DOI: 10.1371/Journal.Pone.0055202  0.256
1998 Mizgerd JP, Quinlan WM, LeBlanc BW, Kutkoski GJ, Bullard DC, Beaudet AL, Doerschuk CM. Combinatorial requirements for adhesion molecules in mediating neutrophil emigration during bacterial peritonitis in mice. Journal of Leukocyte Biology. 64: 291-7. PMID 9738654 DOI: 10.1002/Jlb.64.3.291  0.256
2001 Mizgerd JP, Spieker MR, Doerschuk CM. Early response cytokines and innate immunity: essential roles for TNF receptor 1 and type I IL-1 receptor during Escherichia coli pneumonia in mice. Journal of Immunology (Baltimore, Md. : 1950). 166: 4042-8. PMID 11238652 DOI: 10.4049/Jimmunol.166.6.4042  0.256
2018 Wagner WW, JaryszaK EM, Peterson AJ, Doerschuk CM, Bohlen HG, King JAC, Tanner JA, Crockett ES, Glenny RW, Presson RG. A Perpetual Switching System in Pulmonary Capillaries. Journal of Applied Physiology (Bethesda, Md. : 1985). PMID 30571293 DOI: 10.1152/Japplphysiol.00507.2018  0.255
1992 Hogg JC, Doerschuk CM, Wiggs B, Minshall D. Neutrophil retention during a single transit through the pulmonary circulation. Journal of Applied Physiology (Bethesda, Md. : 1985). 73: 1683-5. PMID 1447121 DOI: 10.1152/jappl.1992.73.4.1683  0.255
2007 Tatro JM, Taki N, Islam AS, Goldberg VM, Rimnac CM, Doerschuk CM, Stewart MC, Greenfield EM. The balance between endotoxin accumulation and clearance during particle-induced osteolysis in murine calvaria. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 25: 361-9. PMID 17106883 DOI: 10.1002/Jor.20289  0.252
2007 Gomez JC, Doerschuk CM. CD18 regulates neutrophil production in the bone marrow The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A178-C  0.251
1996 Kumasaka T, Quinlan WM, Doyle NA, Condon TP, Sligh J, Takei F, Beaudet Al, Bennett CF, Doerschuk CM. Role of the intercellular adhesion molecule-1(ICAM-1) in endotoxin-induced pneumonia evaluated using ICAM-1 antisense oligonucleotides, anti-ICAM-1 monoclonal antibodies, and ICAM-1 mutant mice. The Journal of Clinical Investigation. 97: 2362-9. PMID 8636417 DOI: 10.1172/Jci118679  0.25
1990 Doerschuk CM, Allard MF, Oyarzun MJ. Evaluation of reexpansion pulmonary edema following unilateral pneumothorax in rabbits and the effect of superoxide dismutase. Experimental Lung Research. 16: 355-67. PMID 2394201 DOI: 10.3109/01902149009108850  0.249
1991 Doerschuk CM, Sekhon HS. Pulmonary blood volume and edema in postpneumonectomy lung growth in rats. Journal of Applied Physiology (Bethesda, Md. : 1985). 69: 1178-82. PMID 2246167 DOI: 10.1152/jappl.1990.69.3.1178  0.248
1996 Bullard DC, Kunkel EJ, Kubo H, Hicks MJ, Lorenzo I, Doyle NA, Doerschuk CM, Ley K, Beaudet AL. Infectious susceptibility and severe deficiency of leukocyte rolling and recruitment in E-selectin and P-selectin double mutant mice. The Journal of Experimental Medicine. 183: 2329-36. PMID 8642341 DOI: 10.1084/jem.183.5.2329  0.248
2022 Gomez JC, Doerschuk CM. Hypoxia Can Make Neutrophils Hyper, Potentially Wreaking Havoc During Exacerbations in COPD. American Journal of Respiratory and Critical Care Medicine. PMID 35148486 DOI: 10.1164/rccm.202201-0086ED  0.247
2021 Opron K, Begley LA, Erb-Downward JR, Freeman C, Madapoosi S, Alexis NE, Barjaktarevic I, Graham Barr R, Bleecker ER, Bowler RP, Christenson SA, Comellas AP, Cooper CB, Couper DJ, Doerschuk CM, et al. Lung microbiota associations with clinical features of COPD in the SPIROMICS cohort. Npj Biofilms and Microbiomes. 7: 14. PMID 33547327 DOI: 10.1038/s41522-021-00185-9  0.241
2017 Hastie AT, Martinez FJ, Curtis JL, Doerschuk CM, Hansel NN, Christenson S, Putcha N, Ortega VE, Li X, Barr RG, Carretta EE, Couper DJ, Cooper CB, Hoffman EA, Kanner RE, et al. Association of sputum and blood eosinophil concentrations with clinical measures of COPD severity: an analysis of the SPIROMICS cohort. The Lancet. Respiratory Medicine. PMID 29146301 DOI: 10.1016/S2213-2600(17)30432-0  0.24
1999 Doerschuk CM, Mizgerd JP, Kubo H, Qin L, Kumasaka T. Adhesion molecules and cellular biomechanical changes in acute lung injury: Giles F. Filley Lecture. Chest. 116: 37S-43S. PMID 10424587 DOI: 10.1378/Chest.116.Suppl_1.37S-A  0.239
1995 Tepper RS, Gunst SJ, Doerschuk CM, Shen X, Bray W. Effect of transpulmonary pressure on airway closure in immature and mature rabbits. Journal of Applied Physiology (Bethesda, Md. : 1985). 78: 505-12. PMID 7759419 DOI: 10.1152/jappl.1995.78.2.505  0.238
1999 Etzioni A, Doerschuk CM, Harlan JM. Of Man and Mouse: Leukocyte and Endothelial Adhesion Molecule Deficiencies Blood. 94: 3281-3288. DOI: 10.1182/Blood.V94.10.3281.422K37_3281_3288  0.237
2016 Gomez JC, Dang H, Martin JR, Doerschuk CM. Nrf2 Modulates Host Defense during Streptococcus pneumoniae Pneumonia in Mice. Journal of Immunology (Baltimore, Md. : 1950). PMID 27566827 DOI: 10.4049/jimmunol.1600043  0.232
1991 Brumwell ML, MacNee W, Doerschuk CM, Wiggs B, Hogg JC. Neutrophil kinetics in normal and emphysematous regions of human lungs. Annals of the New York Academy of Sciences. 624: 30-9. PMID 2064230 DOI: 10.1111/J.1749-6632.1991.Tb17003.X  0.231
2018 Monaghan-Benson E, Wittchen ES, Doerschuk CM, Burridge K. A Rnd3/p190RhoGAP pathway regulates RhoA activity in Idiopathic Pulmonary Fibrosis fibroblasts. Molecular Biology of the Cell. mbcE17110642. PMID 29995590 DOI: 10.1091/mbc.E17-11-0642  0.229
1988 Doerschuk CM, Allard MF, Lee S, Brumwell ML, Hogg JC. Effect of epinephrine on neutrophil kinetics in rabbit lungs. Journal of Applied Physiology (Bethesda, Md. : 1985). 65: 401-7. PMID 3403483 DOI: 10.1152/jappl.1988.65.1.401  0.225
1996 Shen X, Bhargava V, Wodicka GR, Doerschuk CM, Gunst SJ, Tepper RS. Greater airway narrowing in immature than in mature rabbits during methacholine challenge Journal of Applied Physiology. 81: 2637-2643. PMID 9018516 DOI: 10.1152/Jappl.1996.81.6.2637  0.224
1993 Klut ME, Doerschuk CM, Van Eeden SF, Burns AR, Hogg JC. Activation of neutrophils within pulmonary microvessels of rabbits exposed to cigarette smoke American Journal of Respiratory Cell and Molecular Biology. 9: 82-89. PMID 7687850 DOI: 10.1165/ajrcmb/9.1.82  0.224
2021 Gomez JC, Doerschuk CM. Correction: Neutrophil DREAM come true: The not-so-impossible quest for mechanisms of neutrophil function and heterogeneity. The Journal of Experimental Medicine. 219. PMID 34962513 DOI: 10.1084/jem.2021214112202021c  0.223
1999 Kubo H, Doyle NA, Graham L, Bhagwan SD, Quinlan WM, Doerschuk CM. L- and P-selectin and CD11/CD18 in intracapillary neutrophil sequestration in rabbit lungs. American Journal of Respiratory and Critical Care Medicine. 159: 267-74. PMID 9872849 DOI: 10.1164/ajrccm.159.1.9709011  0.221
2003 Matthay MA, Zimmerman GA, Esmon C, Bhattacharya J, Coller B, Doerschuk CM, Floros J, Gimbrone MA, Hoffman E, Hubmayr RD, Leppert M, Matalon S, Munford R, Parsons P, Slutsky AS, et al. Future research directions in acute lung injury: summary of a National Heart, Lung, and Blood Institute working group. American Journal of Respiratory and Critical Care Medicine. 167: 1027-35. PMID 12663342 DOI: 10.1164/Rccm.200208-966Ws  0.221
2019 Mock JR, Dial CF, Tune MK, Norton DL, Martin JR, Gomez JC, Hagan RS, Dang H, Doerschuk CM. Transcriptional analysis of Foxp3+ regulatory T cells and functions of two identified molecules during resolution of ALI. Jci Insight. PMID 30753170 DOI: 10.1172/jci.insight.124958  0.218
1995 Hogg JC, Doerschuk CM. Leukocyte traffic in the lung. Annual Review of Physiology. 57: 97-114. PMID 7778886 DOI: 10.1146/annurev.ph.57.030195.000525  0.215
2024 McCullough MJ, Tune MK, Cabrera JC, Torres-Castillo J, He M, Feng Y, Doerschuk CM, Dang H, Beltran AS, Hagan RS, Mock JR. Characterization of the MT-2 Treg-like cell line in the presence and absence of forkhead box P3 (FOXP3). Immunology and Cell Biology. PMID 38288547 DOI: 10.1111/imcb.12725  0.215
2017 Martinez CH, Li SX, Hirzel AJ, Stolberg VR, Alexis NE, Barr RG, Bleecker ER, Carretta EE, Christenson SA, Cooper CB, Couper DJ, Doerschuk CM, Han MK, Hansel NN, Hastie AT, et al. Alveolar eosinophilia in current smokers with chronic obstructive pulmonary disease in the SPIROMICS cohort. The Journal of Allergy and Clinical Immunology. PMID 28916185 DOI: 10.1016/J.Jaci.2017.07.039  0.214
2001 Horwitz BH, Mizgerd JP, Scott ML, Doerschuk CM. Mechanisms of granulocytosis in the absence of CD18. Blood. 97: 1578-83. PMID 11238094 DOI: 10.1182/Blood.V97.6.1578  0.214
2001 Huang Y, Doerschuk CM, Kamm RD. Computational modeling of RBC and neutrophil transit through the pulmonary capillaries. Journal of Applied Physiology (Bethesda, Md. : 1985). 90: 545-64. PMID 11160053 DOI: 10.1152/Jappl.2001.90.2.545  0.214
2018 Dunn JL, Kartchner LB, Stepp WH, Glenn LI, Malfitano MM, Jones S, Doerschuk CM, Maile R, Cairns BA. Blocking CXCL1-dependent neutrophil recruitment prevents pulmonary damage and reduces rick of bacterial infection after inhalation injury. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 29368547 DOI: 10.1152/Ajplung.00272.2017  0.213
2001 Alcamo E, Mizgerd JP, Horwitz BH, Bronson R, Beg AA, Scott M, Doerschuk CM, Hynes RO, Baltimore D. Targeted mutation of TNF receptor I rescues the RelA-deficient mouse and reveals a critical role for NF-kappa B in leukocyte recruitment. Journal of Immunology (Baltimore, Md. : 1950). 167: 1592-600. PMID 11466381 DOI: 10.4049/Jimmunol.167.3.1592  0.212
1988 Allard MF, Doerschuk CM, Brumwell ML, Belzberg A, Hogg JC. Oleic acid-induced lung injury in rabbits: effect of fibrinogen depletion with Arvin. Journal of Applied Physiology (Bethesda, Md. : 1985). 64: 920-8. PMID 3284872 DOI: 10.1152/jappl.1988.64.3.920  0.212
2015 Doerschuk CM. Pulmonary alveolar proteinosis and macrophage transplantation. The New England Journal of Medicine. 372: 1762-4. PMID 25923557 DOI: 10.1056/NEJMcibr1413035  0.209
1997 Mizgerd JP, Kubo H, Kutkoski GJ, Bhagwan SD, Scharffetter-Kochanek K, Beaudet AL, Doerschuk CM. Neutrophil emigration in the skin, lungs, and peritoneum: different requirements for CD11/CD18 revealed by CD18-deficient mice. The Journal of Experimental Medicine. 186: 1357-64. PMID 9334375 DOI: 10.1084/Jem.186.8.1357  0.209
2023 DiLillo KM, Norman KC, Freeman CM, Christenson SA, Alexis NE, Anderson WH, Barjaktarevic IZ, Barr RG, Comellas AP, Bleecker ER, Boucher RC, Couper DJ, Criner GJ, Doerschuk CM, Wells JM, et al. A blood and bronchoalveolar lavage protein signature of rapid FEV decline in smoking-associated COPD. Scientific Reports. 13: 8228. PMID 37217548 DOI: 10.1038/s41598-023-32216-0  0.206
2020 Mock JR, Tune MK, Dial CF, Torres-Castillo J, Hagan RS, Doerschuk CM. Effects of IFN-γ on immune cell kinetics during the resolution of acute lung injury. Physiological Reports. 8: e14368. PMID 32061190 DOI: 10.14814/phy2.14368  0.206
2012 Livraghi-Butrico A, Duncan EA, Saini Y, Dang H, Doerschuk CM, O'Neal WK, Boucher RC. Mechanisms of Host Defense during Airway Mucus Obstruction inScnn1bTransgenic Mice: A Mouse Model Of Chronic Obstructive Pulmonary Disease Proceedings of the American Thoracic Society. 9: 82-83. DOI: 10.1513/pats.9.2.82a  0.205
2002 Mizgerd JP, Scott ML, Spieker MR, Doerschuk CM. Functions of IkappaB proteins in inflammatory responses to Escherichia coli LPS in mouse lungs. American Journal of Respiratory Cell and Molecular Biology. 27: 575-82. PMID 12397017 DOI: 10.1165/Rcmb.2002-0015Oc  0.203
2013 Gomez JC, Wang Q, Doerschuk CM. Neutrophils in acute bacterial pneumonia Mucosal Immunology of Acute Bacterial Pneumonia. 83-124. DOI: 10.1007/978-1-4614-5326-0_4  0.202
2017 Gomez JC, Dang H, Kanke M, Hagan RS, Mock JR, Kelada SNP, Sethupathy P, Doerschuk CM. Predicted effects of observed changes in the mRNA and microRNA transcriptome of lung neutrophils during S. pneumoniae pneumonia in mice. Scientific Reports. 7: 11258. PMID 28900269 DOI: 10.1038/S41598-017-11638-7  0.201
2015 Freeman CM, Crudgington S, Stolberg VR, Brown JP, Sonstein J, Alexis NE, Doerschuk CM, Basta PV, Carretta EE, Couper DJ, Hastie AT, Kaner RJ, O'Neal WK, Paine R, Rennard SI, et al. Design of a multi-center immunophenotyping analysis of peripheral blood, sputum and bronchoalveolar lavage fluid in the Subpopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS). Journal of Translational Medicine. 13: 19. PMID 25622723 DOI: 10.1186/S12967-014-0374-Z  0.201
2020 Dunican EM, Elicker BM, Henry T, Gierada DS, Schiebler ML, Anderson W, Barjaktarevic I, Barr RG, Bleecker ER, Boucher RC, Bowler RP, Christenson SA, Comellas A, Cooper CB, Couper D, ... ... Doerschuk CM, et al. Mucus Plugs and Emphysema in the Pathophysiology of Airflow Obstruction and Hypoxemia in Smokers. American Journal of Respiratory and Critical Care Medicine. PMID 33180550 DOI: 10.1164/rccm.202006-2248OC  0.2
2021 Esther CR, O'Neal WK, Anderson WH, Kesimer M, Ceppe A, Doerschuk CM, Alexis NE, Hastie AT, Barr RG, Bowler RP, Wells JM, Oelsner EC, Comellas AP, Tesfaigzi Y, Kim V, et al. Identification of Sputum Biomarkers Predictive of Pulmonary Exacerbations in Chronic Obstructive Pulmonary Disease. Chest. PMID 34801592 DOI: 10.1016/j.chest.2021.10.049  0.195
2019 Barjaktarevic IZ, Buhr RG, Wang X, Hu S, Couper D, Anderson W, Kanner RE, Paine Iii R, Bhatt SP, Bhakta NR, Arjomandi M, Kaner RJ, Pirozzi CS, Curtis JL, O'Neal WK, ... ... Doerschuk CM, et al. Clinical Significance of Bronchodilator Responsiveness Evaluated by Forced Vital Capacity in COPD: SPIROMICS Cohort Analysis. International Journal of Chronic Obstructive Pulmonary Disease. 14: 2927-2938. PMID 31908441 DOI: 10.2147/Copd.S220164  0.188
1997 De Sanctis GT, Wolyniec WW, Green FH, Qin S, Jiao A, Finn PW, Noonan T, Joetham AA, Gelfand E, Doerschuk CM, Drazen JM. Reduction of allergic airway responses in P-selectin-deficient mice. Journal of Applied Physiology (Bethesda, Md. : 1985). 83: 681-7. PMID 9292449 DOI: 10.1152/jappl.1997.83.3.681  0.187
2012 Kebaier C, Chamberland RR, Allen IC, Gao X, Broglie PM, Hall JD, Jania C, Doerschuk CM, Tilley SL, Duncan JA. Staphylococcus aureus α-hemolysin mediates virulence in a murine model of severe pneumonia through activation of the NLRP3 inflammasome. The Journal of Infectious Diseases. 205: 807-17. PMID 22279123 DOI: 10.1093/Infdis/Jir846  0.187
2010 Gomez JC, Doerschuk CM. The role of CD18 in the production and release of neutrophils from the bone marrow. Laboratory Investigation; a Journal of Technical Methods and Pathology. 90: 599-610. PMID 20142805 DOI: 10.1038/labinvest.2010.4  0.186
2018 Dela Cruz CS, Wunderink RG, Christiani DC, Cormier SA, Crothers K, Doerschuk CM, Evans SE, Goldstein DR, Khatri P, Kobzik L, Kolls JK, Levy BD, Metersky ML, Niederman MS, Nusrat R, et al. Future Research Directions in Pneumonia: NHLBI Working Group Report. American Journal of Respiratory and Critical Care Medicine. PMID 29546996 DOI: 10.1164/Rccm.201801-0139Ws  0.185
1997 Morgenstern DE, Gifford MA, Li LL, Doerschuk CM, Dinauer MC. Absence of respiratory burst in X-linked chronic granulomatous disease mice leads to abnormalities in both host defense and inflammatory response to Aspergillus fumigatus. The Journal of Experimental Medicine. 185: 207-18. PMID 9016870 DOI: 10.1084/Jem.185.2.207  0.184
2023 McPeek MK, Gomez JC, Doerschuk CM. Neutrophils sing "IL[-10] be seeing you" in the lungs during pneumonia. Journal of Leukocyte Biology. PMID 37931143 DOI: 10.1093/jleuko/qiad134  0.182
2023 Mock JR, Tune MK, Bose PG, McCullough MJ, Doerschuk CM. Comparison of Different Methods of Initiating Lung Inflammation and the Sex-Specific Effects on Inflammatory Parameters. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 36594854 DOI: 10.1152/ajplung.00118.2022  0.182
2000 Etzioni A, Doerschuk CM, Harlan JM. Similarities and dissimilarities between humans and mice looking at adhesion molecules defects. Advances in Experimental Medicine and Biology. 479: 147-61. PMID 10897417 DOI: 10.1007/0-306-46831-X_13  0.18
1991 Garland A, Ray DW, Doerschuk CM, Alger L, Eappon S, Hernandez C, Jackson M, Solway J. Role of tachykinins in hyperpnea-induced bronchovascular hyperpermeability in guinea pigs. Journal of Applied Physiology (Bethesda, Md. : 1985). 70: 27-35. PMID 2010383 DOI: 10.1152/jappl.1991.70.1.27  0.179
2017 Kesimer M, Ford AA, Ceppe A, Radicioni G, Cao R, Davis CW, Doerschuk CM, Alexis NE, Anderson WH, Henderson AG, Barr RG, Bleecker ER, Christenson SA, Cooper CB, Han MK, et al. Airway Mucin Concentration as a Marker of Chronic Bronchitis. The New England Journal of Medicine. 377: 911-922. PMID 28877023 DOI: 10.1056/Nejmoa1701632  0.178
1991 Bosken CH, Doerschuk CM, English D, Hogg JC. Neutrophil kinetics during active cigarette smoking in rabbits. Journal of Applied Physiology (Bethesda, Md. : 1985). 71: 630-7. PMID 1657860 DOI: 10.1152/jappl.1991.71.2.630  0.176
2014 O'Neal WK, Anderson W, Basta PV, Carretta EE, Doerschuk CM, Barr RG, Bleecker ER, Christenson SA, Curtis JL, Han MK, Hansel NN, Kanner RE, Kleerup EC, Martinez FJ, Miller BE, et al. Comparison of serum, EDTA plasma and P100 plasma for luminex-based biomarker multiplex assays in patients with chronic obstructive pulmonary disease in the SPIROMICS study. Journal of Translational Medicine. 12: 9. PMID 24397870 DOI: 10.1186/1479-5876-12-9  0.173
1994 Du X, Doerschuk C, Orazi A, Williams D. A bone marrow stromal-derived growth factor, interleukin-11, stimulates recovery of small intestinal mucosal cells after cytoablative therapy Blood. 83: 33-37. DOI: 10.1182/blood.V83.1.33.bloodjournal83133  0.171
1996 Kubo H, Morgenstern D, Quinian WM, Ward PA, Dinauer MC, Doerschuk CM. Preservation of complement-induced lung injury in mice with deficiency of NADPH oxidase. The Journal of Clinical Investigation. 97: 2680-4. PMID 8647963 DOI: 10.1172/Jci118718  0.168
2011 Yamada M, Gomez JC, Chugh PE, Lowell CA, Dinauer MC, Dittmer DP, Doerschuk CM. Interferon-γ production by neutrophils during bacterial pneumonia in mice. American Journal of Respiratory and Critical Care Medicine. 183: 1391-401. PMID 21169470 DOI: 10.1164/Rccm.201004-0592Oc  0.164
2021 Pratte KA, Curtis JL, Kechris K, Couper D, Cho MH, Silverman EK, DeMeo DL, Sciurba FC, Zhang Y, Ortega VE, O'Neal WK, Gillenwater LA, Lynch DA, Hoffman EA, Newell JD, ... ... Doerschuk CM, et al. Soluble receptor for advanced glycation end products (sRAGE) as a biomarker of COPD. Respiratory Research. 22: 127. PMID 33906653 DOI: 10.1186/s12931-021-01686-z  0.162
2019 Engle ML, Monk JN, Jania CM, Martin JR, Gomez JC, Dang H, Parker JS, Doerschuk CM. Dynamic changes in lung responses after single and repeated exposures to cigarette smoke in mice. Plos One. 14: e0212866. PMID 30818335 DOI: 10.1371/Journal.Pone.0212866  0.161
2001 Nasreen N, Mohammed KA, Hardwick J, Van Horn RD, Sanders KL, Doerschuk CM, Hott JW, Antony VB. Polar production of interleukin-8 by mesothelial cells promotes the transmesothelial migration of neutrophils: role of intercellular adhesion molecule-1. The Journal of Infectious Diseases. 183: 1638-45. PMID 11343213 DOI: 10.1086/320700  0.157
2018 Okuda K, Chen G, Subramani DB, Wolf M, Gilmore RC, Kato T, Radicioni G, Kesimer M, Chua M, Dang H, Livraghi-Butrico A, Ehre C, Doerschuk CM, Randell SH, Matsui H, et al. Localization of Secretory Mucins MUC5AC and MUC5B in Normal/Healthy Human Airways. American Journal of Respiratory and Critical Care Medicine. PMID 30352166 DOI: 10.1164/Rccm.201804-0734Oc  0.152
1999 Doerschuk CM. Neutrophil rheology and transit through capillaries and sinusoids. American Journal of Respiratory and Critical Care Medicine. 159: 1693-5. PMID 10351905 DOI: 10.1164/ajrccm.159.6.ed08-99  0.151
1989 Doerschuk CM, Gie RP, Bally MB, Cullis PR, Reinish LW. Platelet Distribution in Rabbits Following lnfusion of Liposomes Thrombosis and Haemostasis. 61: 392-396. DOI: 10.1055/S-0038-1646602  0.146
2020 Keene JD, Jacobson S, Kechris K, Kinney GL, Foreman MG, Doerschuk CM, Make BJ, Curtis JL, Rennard SI, Barr RG, Bleecker ER, Kanner RE, Kleerup EC, Hansel NN, Woodruff PG, et al. Biomarkers Predictive of Exacerbations in the SPIROMICS and COPDGene Cohorts. American Journal of Respiratory and Critical Care Medicine. 201: 473-481. PMID 31891318 DOI: 10.1164/rccm.201607-1330OC.201.1.test  0.142
2016 Sun W, Kechris K, Jacobson S, Drummond MB, Hawkins GA, Yang J, Chen TH, Quibrera PM, Anderson W, Barr RG, Basta PV, Bleecker ER, Beaty T, Casaburi R, Castaldi P, ... ... Doerschuk CM, et al. Common Genetic Polymorphisms Influence Blood Biomarker Measurements in COPD. Plos Genetics. 12: e1006011. PMID 27532455 DOI: 10.1371/Journal.Pgen.1006011  0.14
2011 Duncan E, Martin J, Doerschuk C. Neutrophil-derived Interferon γ (IFNγ) Controls Inducible Nitric Oxide Synthase (Nos2) During Pneumococcal Pneumonia Journal of Allergy and Clinical Immunology. 127: AB97-AB97. DOI: 10.1016/j.jaci.2010.12.392  0.136
2001 Wiesel P, Patel AP, DiFonzo N, Marria PB, Sim CU, Pellacani A, Maemura K, LeBlanc BW, Marino K, Doerschuk CM, Yet SF, Lee ME, Perrella MA. Endotoxin-induced mortality is related to increased oxidative stress and end-organ dysfunction, not refractory hypotension, in heme oxygenase-1-deficient mice. Circulation. 102: 3015-22. PMID 11113055 DOI: 10.1161/01.CIR.102.24.3015  0.133
2020 Zhang WZ, Oromendia C, Kikkers SA, Butler JJ, O'Beirne S, Kim K, O'Neal WK, Freeman CM, Christenson SA, Peters SP, Wells JM, Doerschuk C, Putcha N, Barjaktarevic I, Woodruff PG, et al. Increased airway iron parameters and risk for exacerbation in COPD: an analysis from SPIROMICS. Scientific Reports. 10: 10562. PMID 32601308 DOI: 10.1038/S41598-020-67047-W  0.13
2018 Putcha N, Fawzy A, Paul GG, Lambert AA, Psoter KJ, Sidhaye VK, Woo J, Wells JM, Labaki WW, Doerschuk CM, Kanner RE, Han MK, Martinez C, Paulin LM, Martinez FJ, et al. Anemia and Adverse Outcomes in a Chronic Obstructive Pulmonary Disease Population with a High Burden of Comorbidities. An Analysis from SPIROMICS. Annals of the American Thoracic Society. 15: 710-717. PMID 30726108 DOI: 10.1513/AnnalsATS.201708-687OC  0.127
2015 Hua X, Naselsky WC, Jania CM, Chason KD, Huang JJ, Doerschuk CM, Graham SM, Senior BA, Tilley SL. Mast Cell Deficiency Limits the Development of Chronic Rhinosinusitis in Mice. The Annals of Otology, Rhinology, and Laryngology. PMID 26681624 DOI: 10.1177/0003489415610775  0.125
2001 Shore SA, Schwartzman IN, Le Blanc B, Murthy GG, Doerschuk CM. Tumor necrosis factor receptor 2 contributes to ozone-induced airway hyperresponsiveness in mice. American Journal of Respiratory and Critical Care Medicine. 164: 602-7. PMID 11520723 DOI: 10.1164/ajrccm.164.4.2001016  0.123
2017 Esther CR, Hill DB, Button B, Shi S, Jania CM, Duncan EA, Doerschuk CM, Chen G, Ranganathan S, Stick SM, Boucher RC. The sialic acid to urea ratio as a measure of airway surface hydration. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00398.2016. PMID 28062483 DOI: 10.1152/Ajplung.00398.2016  0.121
1992 Drazenovic R, Samsel RW, Wylam ME, Doerschuk CM, Schumacker PT. Regulation of perfused capillary density in canine intestinal mucosa during endotoxemia. Journal of Applied Physiology (Bethesda, Md. : 1985). 72: 259-65. PMID 1537724 DOI: 10.1152/Jappl.1992.72.1.259  0.119
2023 McKleroy W, Shing T, Anderson WH, Arjomandi M, Awan HA, Barjaktarevic I, Barr RG, Bleecker ER, Boscardin J, Bowler RP, Buhr RG, Criner GJ, Comellas AP, Curtis JL, Dransfield M, ... Doerschuk CM, et al. Longitudinal Follow-Up of Participants With Tobacco Exposure and Preserved Spirometry. Jama. 330: 442-453. PMID 37526720 DOI: 10.1001/jama.2023.11676  0.116
2016 Keene JD, Jacobson S, Kechris K, Kinney GL, Foreman MG, Doerschuk CM, Make BJ, Curtis JL, Rennard SI, Barr RG, Bleecker ER, Kanner RE, Kleerup EC, Hansel NN, Woodruff PG, et al. Biomarkers Predictive of Exacerbations in the SPIROMICS and COPDGene Cohorts. American Journal of Respiratory and Critical Care Medicine. PMID 27579823 DOI: 10.1164/Rccm.201607-1330Oc  0.114
1991 Kirkland JB, Doerschuk CM, Gie R, Boskin C, Hogg JC. Changes measured in arterial blood following a single breath of cigarette smoke in rabbits. Life Sciences. 49: 1013-9. PMID 1653885 DOI: 10.1016/0024-3205(91)90302-R  0.109
1997 Dhadwal A, Wiggs B, Doerschuk CM, Kamm RD. Effects of anatomic variability on blood flow and pressure gradients in the pulmonary capillaries. Journal of Applied Physiology (Bethesda, Md. : 1985). 83: 1711-20. PMID 9375343 DOI: 10.1152/Jappl.1997.83.5.1711  0.109
2020 Burkes RM, Ceppe AS, Doerschuk CM, Couper D, Hoffman EA, Comellas AP, Barr RG, Krishnan JA, Cooper C, Labaki WW, Ortega VE, Wells JM, Criner GJ, Woodruff PG, Bowler RP, et al. Associations between 25-hydroxy-vitamin D levels, lung function, and exacerbation outcomes in COPD: An analysis of the SPIROMICS cohort. Chest. PMID 31958447 DOI: 10.1016/J.Chest.2019.11.047  0.105
2017 Gomez JC, Doerschuk CM. Activating Integrins Isn't Always "Beta" for Neutrophil Migration! American Journal of Respiratory Cell and Molecular Biology. 56: 561-562. PMID 28459388 DOI: 10.1165/rcmb.2017-0066ED  0.103
2020 Abdelwahab SH, Reidel B, Martin JR, Ghosh A, Keating JE, Haridass P, Carpenter J, Glish GL, Tarran R, Doerschuk CM, Kesimer M. Cigarillos Compromise the Mucosal Barrier and Protein Expression in Airway Epithelia. American Journal of Respiratory Cell and Molecular Biology. PMID 32877614 DOI: 10.1165/Rcmb.2019-0085Oc  0.099
2020 Raffield LM, Dang H, Pratte KA, Jacobson S, Gillenwater L, Ampleford E, Barjaktarevic I, Basta P, Clish CB, Comellas AP, Cornell E, Curtis JL, Doerschuk C, Durda P, Emson C, et al. Comparison of Proteomic Assessment Methods in Multiple Cohort Studies. Proteomics. e1900278. PMID 32386347 DOI: 10.1002/Pmic.201900278  0.096
2015 Moore SM, Zhang H, Maeda N, Doerschuk CM, Faber JE. Cardiovascular risk factors cause premature rarefaction of the collateral circulation and greater ischemic tissue injury. Angiogenesis. 18: 265-81. PMID 25862671 DOI: 10.1007/S10456-015-9465-6  0.085
2019 Wetendorf M, Randall LT, Lemma MT, Hurr SH, Pawlak JB, Tarran R, Doerschuk CM, Caron KM. E-Cigarette Exposure Delays Implantation and Causes Reduced Weight Gain in Female Offspring Exposed . Journal of the Endocrine Society. 3: 1907-1916. PMID 31598571 DOI: 10.1210/Js.2019-00216  0.05
2021 Tarran R, Barr RG, Benowitz NL, Bhatnagar A, Chu HW, Dalton P, Doerschuk CM, Drummond MB, Gold DR, Goniewicz ML, Gross ER, Hansel NN, Hopke PK, Kloner RA, Mikheev VB, et al. E-Cigarettes and Cardiopulmonary Health. Function (Oxford, England). 2: zqab004. PMID 33748758 DOI: 10.1093/function/zqab004  0.047
2017 Anderson WH, Ha JW, Couper DJ, O'Neal WK, Barr RG, Bleecker ER, Carretta EE, Cooper CB, Doerschuk CM, Drummond MB, Han MK, Hansel NN, Kim V, Kleerup EC, Martinez FJ, et al. Variability in objective and subjective measures affects baseline values in studies of patients with COPD. Plos One. 12: e0184606. PMID 28934249 DOI: 10.1371/Journal.Pone.0184606  0.047
2017 Schick SF, Blount BC, Jacob P, Saliba NA, Bernert JT, El Hellani A, Jatlow P, Pappas RS, Wang L, Foulds J, Ghosh A, Hecht SS, Gomez JC, Martin JR, Mesaros C, ... ... Doerschuk CM, et al. Biomarkers of Exposure to New and Emerging Tobacco and Nicotine Delivery Products. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00343.2016. PMID 28522563 DOI: 10.1152/Ajplung.00343.2016  0.035
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