Kevin Tracey - Publications

Affiliations: 
Stony Brook University, Stony Brook, NY, United States 
Area:
Biomedical Engineering, Immunology

110 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Yang H, Liu H, Zeng Q, Imperato GH, Addorisio ME, Li J, He M, Cheng KF, Al-Abed Y, Harris HE, Chavan SS, Andersson U, Tracey KJ. Inhibition of HMGB1/RAGE-mediated endocytosis by HMGB1 antagonist box A, anti-HMGB1 antibodies, and cholinergic agonists suppresses inflammation. Molecular Medicine (Cambridge, Mass.). 25: 13. PMID 30975096 DOI: 10.1186/s10020-019-0081-6  0.4
2019 Chen W, Zhu S, Wang Y, Li J, Qiang X, Zhao X, Yang H, D'Angelo J, Becker L, Wang P, Tracey KJ, Wang H. Enhanced Macrophage Pannexin 1 Expression and Hemichannel Activation Exacerbates Lethal Experimental Sepsis. Scientific Reports. 9: 160. PMID 30655582 DOI: 10.1038/s41598-018-37232-z  0.4
2018 Yang H, Wang H, Levine YA, Gunasekaran MK, Wang Y, Addorisio M, Zhu S, Li W, Li J, de Kleijn DP, Olofsson PS, Warren HS, He M, Al-Abed Y, Roth J, ... ... Tracey KJ, et al. Identification of CD163 as an antiinflammatory receptor for HMGB1-haptoglobin complexes. Jci Insight. 3. PMID 30568040 DOI: 10.1172/jci.insight.126617  0.4
2018 Yang H, Wang H, Levine YA, Gunasekaran MK, Wang Y, Addorisio M, Zhu S, Li W, Li J, de Kleijn DP, Olofsson PS, Warren HS, He M, Al-Abed Y, Roth J, ... ... Tracey KJ, et al. Identification of CD163 as an antiinflammatory receptor for HMGB1-haptoglobin complexes. Jci Insight. 3. PMID 30568039 DOI: 10.1172/jci.insight.126616  0.4
2018 Tarnawski L, Reardon C, Caravaca AS, Rosas-Ballina M, Tusche MW, Drake AR, Hudson LK, Hanes WM, Li JH, Parrish WR, Ojamaa K, Al-Abed Y, Faltys M, Pavlov VA, Andersson U, ... ... Tracey KJ, et al. Adenylyl Cyclase 6 Mediates Inhibition of TNF in the Inflammatory Reflex. Frontiers in Immunology. 9: 2648. PMID 30538698 DOI: 10.3389/fimmu.2018.02648  0.44
2018 Deng M, Tang Y, Li W, Wang X, Zhang R, Zhang X, Zhao X, Liu J, Tang C, Liu Z, Huang Y, Peng H, Xiao L, Tang D, Scott MJ, ... ... Tracey KJ, et al. The Endotoxin Delivery Protein HMGB1 Mediates Caspase-11-Dependent Lethality in Sepsis. Immunity. PMID 30314759 DOI: 10.1016/j.immuni.2018.08.016  0.4
2018 Shah BS, Burt KG, Jacobsen T, Fernandes TD, Alipui DO, Weber KT, Levine M, Chavan SS, Yang H, Tracey KJ, Chahine NO. High mobility group box-1 induces pro-inflammatory signaling in human Nucleus Pulposus cells via Toll-like receptor 4-dependent pathway. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. PMID 30273982 DOI: 10.1002/jor.24154  0.4
2018 Li S, Liang F, Kwan K, Tang Y, Wang X, Tang Y, Li J, Yang H, Chavan SS, Wang H, Andersson U, Lu B, Tracey KJ. Identification of ethyl pyruvate as a NLRP3 inflammasome inhibitor that preserves mitochondrial integrity. Molecular Medicine (Cambridge, Mass.). 24: 8. PMID 30134814 DOI: 10.1186/s10020-018-0006-9  0.4
2018 Li W, Bao G, Chen W, Qiang X, Zhu S, Wang S, He M, Ma G, Ochani M, Al-Abed Y, Yang H, Tracey KJ, Wang P, D'Angelo J, Wang H. Connexin 43 Hemichannel as a Novel Mediator of Sterile and Infectious Inflammatory Diseases. Scientific Reports. 8: 166. PMID 29317708 DOI: 10.1038/s41598-017-18452-1  0.4
2017 Qiang X, Liotta AS, Shiloach J, Gutierrez JC, Wang H, Ochani M, Ochani K, Yang H, Rabin A, LeRoith D, Lesniak MA, Böhm M, Maaser C, Kannengiesser K, Donowitz M, ... ... Tracey KJ, et al. New melanocortin-like peptide of E. coli can suppress inflammation via the mammalian melanocortin-1 receptor (MC1R): possible endocrine-like function for microbes of the gut. Npj Biofilms and Microbiomes. 3: 31. PMID 29152323 DOI: 10.1038/s41522-017-0039-9  0.8
2017 Yang H, Wang H, Wang Y, Addorisio M, Li J, Postiglione MJ, Chavan SS, Al-Abed Y, Antoine DJ, Andersson U, Tracey KJ. The haptoglobin beta subunit sequesters HMGB1 toxicity in sterile and infectious inflammation. Journal of Internal Medicine. PMID 28464519 DOI: 10.1111/joim.12619  0.4
2016 Zhu S, Wang Y, Chen W, Li W, Wang A, Wong S, Bao G, Li J, Yang H, Tracey KJ, D'Angelo J, Wang H. High-Density Lipoprotein (HDL) Counter-Regulates Serum Amyloid A (SAA)-Induced sPLA2-IIE and sPLA2-V Expression in Macrophages. Plos One. 11: e0167468. PMID 27898742 DOI: 10.1371/journal.pone.0167468  0.4
2016 Roth J, Sahota N, Patel P, Mehdi SF, Wiese MM, Mahboob HB, Bravo M, Eden DJ, Bashir MA, Kumar A, Alsaati F, Kurland IJ, Brima W, Danoff A, Szulc AL, ... ... Tracey KJ, et al. Obesity paradox, obesity orthodox, and the metabolic syndrome: An approach to unity. Molecular Medicine (Cambridge, Mass.). 22. PMID 27878212 DOI: 10.2119/molmed.2016.00211  0.4
2016 Kang R, Zeng L, Xie Y, Yan Z, Zhou B, Cao L, Klionsky DJ, Tracey KJ, Li J, Wang H, Billiar TR, Jiang J, Tang D. A Novel PINK1- and PARK2-dependent Protective Neuroimmune Pathway in Lethal Sepsis. Autophagy. 0. PMID 27754761 DOI: 10.1080/15548627.2016.1239678  0.36
2016 Olofsson PS, Steinberg BE, Sobbi R, Cox MA, Ahmed MN, Oswald M, Szekeres F, Hanes WM, Introini A, Liu SF, Holodick NE, Rothstein TL, Lövdahl C, Chavan SS, Yang H, ... ... Tracey KJ, et al. Blood pressure regulation by CD4(+) lymphocytes expressing choline acetyltransferase. Nature Biotechnology. PMID 27617738 DOI: 10.1038/nbt.3663  0.4
2016 Lundbäck P, Lea JD, Sowinska A, Ottosson L, Melin Fürst C, Steen J, Aulin C, Clarke JI, Kipar A, Klevenvall L, Yang H, Palmblad K, Park BK, Tracey KJ, Blom AM, et al. A novel HMGB1 neutralizing chimeric antibody attenuates DILI and post-injury inflammation. Hepatology (Baltimore, Md.). PMID 27474782 DOI: 10.1002/hep.28736  0.4
2016 Hudson LK, Dancho ME, Li J, Bruchfeld JB, Ragab AA, He MM, Bragg M, Lenaghan D, Quinn MD, Fritz JR, Tanzi MV, Silverman HA, Hanes WM, Levine YA, Pavlov VA, ... ... Tracey KJ, et al. Emetine Di-HCl attenuates Type 1 diabetes mellitus in mice. Molecular Medicine (Cambridge, Mass.). 22. PMID 27341452 DOI: 10.2119/molmed.2016.00082  0.36
2016 Yang H, Wang H, Levine YA, Gunasekaran MK, Wang Y, Addorisio M, Zhu S, Li W, Li J, de Kleijn DP, Olofsson PS, Warren HS, He M, Al-Abed Y, Roth J, ... ... Tracey KJ, et al. Identification of CD163 as an antiinflammatory receptor for HMGB1-haptoglobin complexes. Jci Insight. 1. PMID 27294203 DOI: 10.1172/jci.insight.85375  0.4
2015 Valdés-Ferrer SI, Papoin J, Dancho ME, Olofsson P, Li J, Lipton JM, Avancena P, Yang H, Zou YR, Chavan SS, Volpe BT, Gardenghi S, Rivella S, Diamond B, Andersson U, ... ... Tracey KJ, et al. HMGB1 mediates anemia of inflammation in murine sepsis survivors. Molecular Medicine (Cambridge, Mass.). PMID 26736178 DOI: 10.2119/molmed.2015.00243  0.4
2015 Lu B, Tang Y, Zhao X, Antoine D, Xiao X, Wang H, Andersson U, Billiar T, Tracey KJ. Regulation of post-translational modifications of HMGB1 during immune responses. Antioxidants & Redox Signaling. PMID 26715031 DOI: 10.1089/ars.2015.6409  0.36
2015 Cai J, Yuan H, Wang Q, Yang H, Al-Abed Y, Hua Z, Wang J, Chen D, Wu J, Lu B, Pribis JP, Jiang W, Yang K, Hackam DJ, Tracey KJ, et al. HMGB1-Driven Inflammation and Intimal Hyperplasia After Arterial Injury Involves Cell-Specific Actions Mediated by TLR4. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 26515416 DOI: 10.1161/ATVBAHA.115.305789  0.4
2015 Pribis JP, Al-Abed Y, Yang H, Gero D, Xu H, Montenegro MF, Bauer EM, Kim S, Chavan SS, Cai C, Li T, Szoleczky P, Szabo C, Tracey KJ, Billiar TR. The HIV protease inhibitor saquinavir inhibits HMGB1 driven inflammation by targeting the interaction of cathepsin V with TLR4/MyD88. Molecular Medicine (Cambridge, Mass.). PMID 26349060 DOI: 10.2119/molmed.2015.00197  0.4
2015 Hanes WM, Olofsson PS, Kwan K, Hudson LK, Chavan SS, Pavlov VA, Tracey KJ. Galantamine Attenuates Type 1 Diabetes and Inhibits Anti-Insulin Antibodies in Non-Obese Diabetic Mice. Molecular Medicine (Cambridge, Mass.). PMID 26322849 DOI: 10.2119/molmed.2015.00142  0.44
2015 Li W, Zhu S, Li J, D'amore J, D'angelo J, Yang H, Wang P, Tracey KJ, Wang H. Serum Amyloid A Stimulates PKR Expression and HMGB1 Release Possibly through TLR4/RAGE Receptors. Molecular Medicine (Cambridge, Mass.). PMID 26052716 DOI: 10.2119/molmed.2015.00109  0.4
2015 Liesz A, Dalpke A, Mracsko E, Antoine DJ, Roth S, Zhou W, Yang H, Na SY, Akhisaroglu M, Fleming T, Eigenbrod T, Nawroth PP, Tracey KJ, Veltkamp R. DAMP signaling is a key pathway inducing immune modulation after brain injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 583-98. PMID 25589753 DOI: 10.1523/JNEUROSCI.2439-14.2015  0.44
2015 Weber MD, Frank MG, Tracey KJ, Watkins LR, Maier SF. Stress induces the danger-associated molecular pattern HMGB-1 in the hippocampus of male Sprague Dawley rats: a priming stimulus of microglia and the NLRP3 inflammasome. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 316-24. PMID 25568124 DOI: 10.1523/JNEUROSCI.3561-14.2015  0.44
2015 Yang H, Wang H, Ju Z, Ragab AA, Lundbäck P, Long W, Valdes-Ferrer SI, He M, Pribis JP, Li J, Lu B, Gero D, Szabo C, Antoine DJ, Harris HE, ... ... Tracey KJ, et al. MD-2 is required for disulfide HMGB1-dependent TLR4 signaling. The Journal of Experimental Medicine. 212: 5-14. PMID 25559892 DOI: 10.1084/jem.20141318  0.44
2015 Rosas-Ballina M, Valdés-Ferrer SI, Dancho ME, Ochani M, Katz D, Cheng KF, Olofsson PS, Chavan SS, Al-Abed Y, Tracey KJ, Pavlov VA. Xanomeline suppresses excessive pro-inflammatory cytokine responses through neural signal-mediated pathways and improves survival in lethal inflammation. Brain, Behavior, and Immunity. 44: 19-27. PMID 25063706 DOI: 10.1016/j.bbi.2014.07.010  0.44
2014 Cerami A, Tracey KJ. Farewell statement from Dr. Cerami and Dr. Tracey as outgoing co-Editors in Chief of Molecular Medicine. Molecular Medicine (Cambridge, Mass.). 20: 329-30. PMID 25356559 DOI: 10.2119/molmed.2014.00151  0.44
2014 Munyaka P, Rabbi MF, Pavlov VA, Tracey KJ, Khafipour E, Ghia JE. Central muscarinic cholinergic activation alters interaction between splenic dendritic cell and CD4+CD25- T cells in experimental colitis. Plos One. 9: e109272. PMID 25295619 DOI: 10.1371/journal.pone.0109272  0.44
2014 Parker KH, Sinha P, Horn LA, Clements VK, Yang H, Li J, Tracey KJ, Ostrand-Rosenberg S. HMGB1 enhances immune suppression by facilitating the differentiation and suppressive activity of myeloid-derived suppressor cells. Cancer Research. 74: 5723-33. PMID 25164013 DOI: 10.1158/0008-5472.CAN-13-2347  0.44
2014 Ju Z, Chavan SS, Antoine DJ, Dancho M, Tsaava T, Li J, Lu B, Levine YA, Stiegler A, Tamari Y, Al-Abed Y, Roth J, Tracey KJ, Yang H. Sequestering HMGB1 via DNA-conjugated beads ameliorates murine colitis. Plos One. 9: e103992. PMID 25127031 DOI: 10.1371/journal.pone.0103992  0.4
2014 Lu B, Kwan K, Levine YA, Olofsson PS, Yang H, Li J, Joshi S, Wang H, Andersson U, Chavan SS, Tracey KJ. α7 nicotinic acetylcholine receptor signaling inhibits inflammasome activation by preventing mitochondrial DNA release. Molecular Medicine (Cambridge, Mass.). 20: 350-8. PMID 24849809 DOI: 10.2119/molmed.2013.00117  0.4
2014 Lu B, Wang C, Wang M, Li W, Chen F, Tracey KJ, Wang H. Molecular mechanism and therapeutic modulation of high mobility group box 1 release and action: an updated review. Expert Review of Clinical Immunology. 10: 713-27. PMID 24746113 DOI: 10.1586/1744666X.2014.909730  0.36
2014 Antoine DJ, Harris HE, Andersson U, Tracey KJ, Bianchi ME. A systematic nomenclature for the redox states of high mobility group box (HMGB) proteins. Molecular Medicine (Cambridge, Mass.). 20: 135-7. PMID 24531895 DOI: 10.2119/molmed.2014.00022  0.44
2014 Lu B, Antoine DJ, Kwan K, Lundbäck P, Wähämaa H, Schierbeck H, Robinson M, Van Zoelen MA, Yang H, Li J, Erlandsson-Harris H, Chavan SS, Wang H, Andersson U, Tracey KJ. JAK/STAT1 signaling promotes HMGB1 hyperacetylation and nuclear translocation. Proceedings of the National Academy of Sciences of the United States of America. 111: 3068-73. PMID 24469805 DOI: 10.1073/pnas.1316925111  0.4
2014 Kang R, Zhang Q, Hou W, Yan Z, Chen R, Bonaroti J, Bansal P, Billiar TR, Tsung A, Wang Q, Bartlett DL, Whitcomb DC, Chang EB, Zhu X, Wang H, ... ... Tracey KJ, et al. Intracellular Hmgb1 inhibits inflammatory nucleosome release and limits acute pancreatitis in mice. Gastroenterology. 146: 1097-107. PMID 24361123 DOI: 10.1053/j.gastro.2013.12.015  0.44
2013 Achouiti A, van der Meer AJ, Florquin S, Yang H, Tracey KJ, van 't Veer C, de Vos AF, van der Poll T. High-mobility group box 1 and the receptor for advanced glycation end products contribute to lung injury during Staphylococcus aureus pneumonia. Critical Care (London, England). 17: R296. PMID 24342460 DOI: 10.1186/cc13162  0.44
2013 Qiang X, Yang WL, Wu R, Zhou M, Jacob A, Dong W, Kuncewitch M, Ji Y, Yang H, Wang H, Fujita J, Nicastro J, Coppa GF, Tracey KJ, Wang P. Cold-inducible RNA-binding protein (CIRP) triggers inflammatory responses in hemorrhagic shock and sepsis. Nature Medicine. 19: 1489-95. PMID 24097189 DOI: 10.1038/nm.3368  0.44
2013 Valdés-Ferrer SI, Rosas-Ballina M, Olofsson PS, Lu B, Dancho ME, Li J, Yang H, Pavlov VA, Chavan SS, Tracey KJ. High-mobility group box 1 mediates persistent splenocyte priming in sepsis survivors: evidence from a murine model. Shock (Augusta, Ga.). 40: 492-5. PMID 24089009 DOI: 10.1097/SHK.0000000000000050  0.4
2013 Zhao L, Li W, Zhu S, Tsai S, Li J, Tracey KJ, Wang P, Fan S, Sama AE, Wang H. Green tea catechins quench the fluorescence of bacteria-conjugated Alexa fluor dyes. Inflammation & Allergy Drug Targets. 12: 308-14. PMID 24011199  0.36
2013 Vincent JL, Opal SM, Marshall JC, Tracey KJ. Sepsis definitions - Authors' reply. Lancet (London, England). 381: 2250. PMID 23809556 DOI: 10.1016/S0140-6736(13)61476-2  0.44
2013 Gerö D, Szoleczky P, Módis K, Pribis JP, Al-Abed Y, Yang H, Chevan S, Billiar TR, Tracey KJ, Szabo C. Identification of pharmacological modulators of HMGB1-induced inflammatory response by cell-based screening. Plos One. 8: e65994. PMID 23799067 DOI: 10.1371/journal.pone.0065994  0.4
2013 Famm K, Litt B, Tracey KJ, Boyden ES, Slaoui M. Drug discovery: a jump-start for electroceuticals. Nature. 496: 159-61. PMID 23579662 DOI: 10.1038/496159a  0.44
2013 Lu B, Wang H, Andersson U, Tracey KJ. Regulation of HMGB1 release by inflammasomes. Protein & Cell. 4: 163-7. PMID 23483477 DOI: 10.1007/s13238-012-2118-2  0.36
2013 Vincent JL, Opal SM, Marshall JC, Tracey KJ. Sepsis definitions: time for change. Lancet (London, England). 381: 774-5. PMID 23472921 DOI: 10.1016/S0140-6736(12)61815-7  0.44
2013 Yang H, Antoine DJ, Andersson U, Tracey KJ. The many faces of HMGB1: molecular structure-functional activity in inflammation, apoptosis, and chemotaxis. Journal of Leukocyte Biology. 93: 865-73. PMID 23446148 DOI: 10.1189/jlb.1212662  0.4
2013 Tadie JM, Bae HB, Jiang S, Park DW, Bell CP, Yang H, Pittet JF, Tracey K, Thannickal VJ, Abraham E, Zmijewski JW. HMGB1 promotes neutrophil extracellular trap formation through interactions with Toll-like receptor 4. American Journal of Physiology. Lung Cellular and Molecular Physiology. 304: L342-9. PMID 23316068 DOI: 10.1152/ajplung.00151.2012  0.4
2013 Reardon C, Duncan GS, Brüstle A, Brenner D, Tusche MW, Olofsson PS, Olofsson P, Rosas-Ballina M, Tracey KJ, Mak TW. Lymphocyte-derived ACh regulates local innate but not adaptive immunity. Proceedings of the National Academy of Sciences of the United States of America. 110: 1410-5. PMID 23297238 DOI: 10.1073/pnas.1221655110  0.44
2013 Patel VS, Sitapara RA, Gore A, Phan B, Sharma L, Sampat V, Li JH, Yang H, Chavan SS, Wang H, Tracey KJ, Mantell LL. High Mobility Group Box-1 mediates hyperoxia-induced impairment of Pseudomonas aeruginosa clearance and inflammatory lung injury in mice. American Journal of Respiratory Cell and Molecular Biology. 48: 280-7. PMID 23087050 DOI: 10.1165/rcmb.2012-0279OC  0.4
2012 Zhang Y, Li W, Zhu S, Jundoria A, Li J, Yang H, Fan S, Wang P, Tracey KJ, Sama AE, Wang H. Tanshinone IIA sodium sulfonate facilitates endocytic HMGB1 uptake. Biochemical Pharmacology. 84: 1492-500. PMID 23022229 DOI: 10.1016/j.bcp.2012.09.015  0.4
2012 Venereau E, Casalgrandi M, Schiraldi M, Antoine DJ, Cattaneo A, De Marchis F, Liu J, Antonelli A, Preti A, Raeli L, Shams SS, Yang H, Varani L, Andersson U, Tracey KJ, et al. Mutually exclusive redox forms of HMGB1 promote cell recruitment or proinflammatory cytokine release. The Journal of Experimental Medicine. 209: 1519-28. PMID 22869893 DOI: 10.1084/jem.20120189  0.44
2012 Chan JK, Roth J, Oppenheim JJ, Tracey KJ, Vogl T, Feldmann M, Horwood N, Nanchahal J. Alarmins: awaiting a clinical response. The Journal of Clinical Investigation. 122: 2711-9. PMID 22850880 DOI: 10.1172/JCI62423  0.44
2012 Lu B, Nakamura T, Inouye K, Li J, Tang Y, Lundbäck P, Valdes-Ferrer SI, Olofsson PS, Kalb T, Roth J, Zou Y, Erlandsson-Harris H, Yang H, Ting JP, Wang H, ... ... Tracey KJ, et al. Novel role of PKR in inflammasome activation and HMGB1 release. Nature. 488: 670-4. PMID 22801494 DOI: 10.1038/nature11290  0.44
2012 Lin T, Sammy F, Yang H, Thundivalappil S, Hellman J, Tracey KJ, Warren HS. Identification of hemopexin as an anti-inflammatory factor that inhibits synergy of hemoglobin with HMGB1 in sterile and infectious inflammation Journal of Immunology. 189: 2017-2022. PMID 22772444 DOI: 10.4049/jimmunol.1103623  0.44
2012 Chavan SS, Huerta PT, Robbiati S, Valdes-Ferrer SI, Ochani M, Dancho M, Frankfurt M, Volpe BT, Tracey KJ, Diamond B. HMGB1 mediates cognitive impairment in sepsis survivors. Molecular Medicine (Cambridge, Mass.). 18: 930-7. PMID 22634723 DOI: 10.2119/molmed.2012.00195  0.44
2012 Entezari M, Weiss DJ, Sitapara R, Whittaker L, Wargo MJ, Li J, Wang H, Yang H, Sharma L, Phan BD, Javdan M, Chavan SS, Miller EJ, Tracey KJ, Mantell LL. Inhibition of high-mobility group box 1 protein (HMGB1) enhances bacterial clearance and protects against Pseudomonas Aeruginosa pneumonia in cystic fibrosis. Molecular Medicine (Cambridge, Mass.). 18: 477-85. PMID 22314397 DOI: 10.2119/molmed.2012.00024  0.44
2012 Olofsson PS, Katz DA, Rosas-Ballina M, Levine YA, Ochani M, Valdés-Ferrer SI, Pavlov VA, Tracey KJ, Chavan SS. α7 nicotinic acetylcholine receptor (α7nAChR) expression in bone marrow-derived non-T cells is required for the inflammatory reflex. Molecular Medicine (Cambridge, Mass.). 18: 539-43. PMID 22183893 DOI: 10.2119/molmed.2011.00405  0.44
2012 Yang H, Lundbäck P, Ottosson L, Erlandsson-Harris H, Venereau E, Bianchi ME, Al-Abed Y, Andersson U, Tracey KJ, Antoine DJ. Redox modification of cysteine residues regulates the cytokine activity of high mobility group box-1 (HMGB1). Molecular Medicine (Cambridge, Mass.). 18: 250-9. PMID 22105604 DOI: 10.2119/molmed.2011.00389  0.4
2012 Dessing MC, Pulskens WP, Teske GJ, Butter LM, van der Poll T, Yang H, Tracey KJ, Nawroth PP, Bierhaus A, Florquin S, Leemans JC. RAGE does not contribute to renal injury and damage upon ischemia/reperfusion-induced injury. Journal of Innate Immunity. 4: 80-5. PMID 22067944 DOI: 10.1159/000334251  0.4
2011 Diamond B, Huerta PT, Tracey K, Volpe BT. It takes guts to grow a brain: Increasing evidence of the important role of the intestinal microflora in neuro- and immune-modulatory functions during development and adulthood. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 33: 588-91. PMID 21681774 DOI: 10.1002/bies.201100042  0.44
2011 Al-Abed Y, Metz CN, Cheng KF, Aljabari B, VanPatten S, Blau S, Lee H, Ochani M, Pavlov VA, Coleman T, Meurice N, Tracey KJ, Miller EJ. Thyroxine is a potential endogenous antagonist of macrophage migration inhibitory factor (MIF) activity. Proceedings of the National Academy of Sciences of the United States of America. 108: 8224-7. PMID 21536912 DOI: 10.1073/pnas.1017624108  0.44
2011 Li W, Zhu S, Li J, Assa A, Jundoria A, Xu J, Fan S, Eissa NT, Tracey KJ, Sama AE, Wang H. EGCG stimulates autophagy and reduces cytoplasmic HMGB1 levels in endotoxin-stimulated macrophages. Biochemical Pharmacology. 81: 1152-63. PMID 21371444 DOI: 10.1016/j.bcp.2011.02.015  0.36
2011 Diamond B, Tracey KJ. Mapping the immunological homunculus. Proceedings of the National Academy of Sciences of the United States of America. 108: 3461-2. PMID 21368214 DOI: 10.1073/pnas.1100329108  0.44
2011 Norman GJ, Morris JS, Karelina K, Weil ZM, Zhang N, Al-Abed Y, Brothers HM, Wenk GL, Pavlov VA, Tracey KJ, Devries AC. Cardiopulmonary arrest and resuscitation disrupts cholinergic anti-inflammatory processes: a role for cholinergic α7 nicotinic receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 3446-52. PMID 21368056 DOI: 10.1523/JNEUROSCI.4558-10.2011  0.44
2011 Li W, Zhu S, Li J, Huang Y, Zhou R, Fan X, Yang H, Gong X, Eissa NT, Jahnen-Dechent W, Wang P, Tracey KJ, Sama AE, Wang H. A hepatic protein, fetuin-A, occupies a protective role in lethal systemic inflammation. Plos One. 6: e16945. PMID 21347455 DOI: 10.1371/journal.pone.0016945  0.4
2010 Tang D, Kang R, Livesey KM, Cheh CW, Farkas A, Loughran P, Hoppe G, Bianchi ME, Tracey KJ, Zeh HJ, Lotze MT. Endogenous HMGB1 regulates autophagy. The Journal of Cell Biology. 190: 881-92. PMID 20819940 DOI: 10.1083/jcb.200911078  0.44
2010 Lamkanfi M, Sarkar A, Vande Walle L, Vitari AC, Amer AO, Wewers MD, Tracey KJ, Kanneganti TD, Dixit VM. Inflammasome-dependent release of the alarmin HMGB1 in endotoxemia. Journal of Immunology (Baltimore, Md. : 1950). 185: 4385-92. PMID 20802146 DOI: 10.4049/jimmunol.1000803  0.44
2010 Yang H, Hreggvidsdottir HS, Palmblad K, Wang H, Ochani M, Li J, Lu B, Chavan S, Rosas-Ballina M, Al-Abed Y, Akira S, Bierhaus A, Erlandsson-Harris H, Andersson U, Tracey KJ. A critical cysteine is required for HMGB1 binding to Toll-like receptor 4 and activation of macrophage cytokine release. Proceedings of the National Academy of Sciences of the United States of America. 107: 11942-7. PMID 20547845 DOI: 10.1073/pnas.1003893107  0.4
2010 de Souza JB, Okomo U, Alexander ND, Aziz N, Owens BM, Kaur H, Jasseh M, Muangnoicharoen S, Sumariwalla PF, Warhurst DC, Ward SA, Conway DJ, Ulloa L, Tracey KJ, Foxwell BM, et al. Oral activated charcoal prevents experimental cerebral malaria in mice and in a randomized controlled clinical trial in man did not interfere with the pharmacokinetics of parenteral artesunate. Plos One. 5: e9867. PMID 20419161 DOI: 10.1371/journal.pone.0009867  0.44
2010 van Zoelen MA, Achouiti A, Schmidt AM, Yang H, Florquin S, Tracey KJ, van der Poll T. Ligands of the receptor for advanced glycation end products, including high-mobility group box 1, limit bacterial dissemination during Escherichia coli peritonitis. Critical Care Medicine. 38: 1414-22. PMID 20386310 DOI: 10.1097/CCM.0b013e3181de18bc  0.4
2010 Loram LC, Harrison JA, Chao L, Taylor FR, Reddy A, Travis CL, Giffard R, Al-Abed Y, Tracey K, Maier SF, Watkins LR. Intrathecal injection of an alpha seven nicotinic acetylcholine receptor agonist attenuates gp120-induced mechanical allodynia and spinal pro-inflammatory cytokine profiles in rats. Brain, Behavior, and Immunity. 24: 959-67. PMID 20353818 DOI: 10.1016/j.bbi.2010.03.008  0.44
2010 Wang H, Li W, Zhu S, Li J, D'Amore J, Ward MF, Yang H, Wu R, Jahnen-Dechent W, Tracey KJ, Wang P, Sama AE. Peripheral administration of fetuin-A attenuates early cerebral ischemic injury in rats. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 30: 493-504. PMID 19953099 DOI: 10.1038/jcbfm.2009.247  0.4
2010 Czura CJ, Schultz A, Kaipel M, Khadem A, Huston JM, Pavlov VA, Redl H, Tracey KJ. Vagus nerve stimulation regulates hemostasis in swine. Shock (Augusta, Ga.). 33: 608-13. PMID 19953009 DOI: 10.1097/SHK.0b013e3181cc0183  0.8
2010 Yang H, Tracey KJ. Targeting HMGB1 in inflammation. Biochimica Et Biophysica Acta. 1799: 149-56. PMID 19948257 DOI: 10.1016/j.bbagrm.2009.11.019  0.4
2009 Miksa M, Wu R, Dong W, Komura H, Amin D, Ji Y, Wang Z, Wang H, Ravikumar TS, Tracey KJ, Wang P. Immature dendritic cell-derived exosomes rescue septic animals via milk fat globule epidermal growth factor-factor VIII [corrected]. Journal of Immunology (Baltimore, Md. : 1950). 183: 5983-90. PMID 19812188 DOI: 10.4049/jimmunol.0802994  0.36
2009 Zhu S, Ashok M, Li J, Li W, Yang H, Wang P, Tracey KJ, Sama AE, Wang H. Spermine protects mice against lethal sepsis partly by attenuating surrogate inflammatory markers. Molecular Medicine (Cambridge, Mass.). 15: 275-82. PMID 19593412 DOI: 10.2119/molmed.2009.00062  0.4
2009 Rosas-Ballina M, Goldstein RS, Gallowitsch-Puerta M, Yang L, Valdés-Ferrer SI, Patel NB, Chavan S, Al-Abed Y, Yang H, Tracey KJ. The selective alpha7 agonist GTS-21 attenuates cytokine production in human whole blood and human monocytes activated by ligands for TLR2, TLR3, TLR4, TLR9, and RAGE. Molecular Medicine (Cambridge, Mass.). 15: 195-202. PMID 19593403 DOI: 10.2119/molmed.2009.00039  0.44
2009 van Zoelen MA, van der Sluijs KF, Achouiti A, Florquin S, Braun-Pater JM, Yang H, Nawroth PP, Tracey KJ, Bierhaus A, van der Poll T. Receptor for advanced glycation end products is detrimental during influenza A virus pneumonia. Virology. 391: 265-73. PMID 19592063 DOI: 10.1016/j.virol.2009.05.032  0.4
2009 van Zoelen MA, Yang H, Florquin S, Meijers JC, Akira S, Arnold B, Nawroth PP, Bierhaus A, Tracey KJ, van der Poll T. Role of toll-like receptors 2 and 4, and the receptor for advanced glycation end products in high-mobility group box 1-induced inflammation in vivo. Shock (Augusta, Ga.). 31: 280-4. PMID 19218854 DOI: 10.1097/SHK.0b013e318186262d  0.4
2008 Parrish WR, Gallowitsch-Puerta M, Czura CJ, Tracey KJ. Experimental therapeutic strategies for severe sepsis: mediators and mechanisms. Annals of the New York Academy of Sciences. 1144: 210-36. PMID 19076379 DOI: 10.1196/annals.1418.011  0.44
2008 Muhammad S, Barakat W, Stoyanov S, Murikinati S, Yang H, Tracey KJ, Bendszus M, Rossetti G, Nawroth PP, Bierhaus A, Schwaninger M. The HMGB1 receptor RAGE mediates ischemic brain damage. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 12023-31. PMID 19005067 DOI: 10.1523/JNEUROSCI.2435-08.2008  0.4
2008 Parrish WR, Rosas-Ballina M, Gallowitsch-Puerta M, Ochani M, Ochani K, Yang LH, Hudson L, Lin X, Patel N, Johnson SM, Chavan S, Goldstein RS, Czura CJ, Miller EJ, Al-Abed Y, ... Tracey KJ, et al. Modulation of TNF release by choline requires alpha7 subunit nicotinic acetylcholine receptor-mediated signaling. Molecular Medicine (Cambridge, Mass.). 14: 567-74. PMID 18584048 DOI: 10.2119/2008-00079.Parrish  0.44
2007 Huston JM, Gallowitsch-Puerta M, Ochani M, Ochani K, Yuan R, Rosas-Ballina M, Ashok M, Goldstein RS, Chavan S, Pavlov VA, Metz CN, Yang H, Czura CJ, Wang H, Tracey KJ. Transcutaneous vagus nerve stimulation reduces serum high mobility group box 1 levels and improves survival in murine sepsis. Critical Care Medicine. 35: 2762-8. PMID 17901837 DOI: 10.1097/01.CCM.0000288102.15975.BA  0.8
2007 Goldstein RS, Bruchfeld A, Yang L, Qureshi AR, Gallowitsch-Puerta M, Patel NB, Huston BJ, Chavan S, Rosas-Ballina M, Gregersen PK, Czura CJ, Sloan RP, Sama AE, Tracey KJ. Cholinergic anti-inflammatory pathway activity and High Mobility Group Box-1 (HMGB1) serum levels in patients with rheumatoid arthritis. Molecular Medicine (Cambridge, Mass.). 13: 210-5. PMID 17597834 DOI: 10.2119/2006–00108.Goldstein  0.8
2007 Pavlov VA, Ochani M, Yang LH, Gallowitsch-Puerta M, Ochani K, Lin X, Levi J, Parrish WR, Rosas-Ballina M, Czura CJ, Larosa GJ, Miller EJ, Tracey KJ, Al-Abed Y. Selective alpha7-nicotinic acetylcholine receptor agonist GTS-21 improves survival in murine endotoxemia and severe sepsis. Critical Care Medicine. 35: 1139-44. PMID 17334244 DOI: 10.1097/01.CCM.0000259381.56526.96  0.44
2006 Yu M, Wang H, Ding A, Golenbock DT, Latz E, Czura CJ, Fenton MJ, Tracey KJ, Yang H. HMGB1 signals through toll-like receptor (TLR) 4 and TLR2. Shock (Augusta, Ga.). 26: 174-9. PMID 16878026 DOI: 10.1097/01.shk.0000225404.51320.82  0.8
2006 Qin S, Wang H, Yuan R, Li H, Ochani M, Ochani K, Rosas-Ballina M, Czura CJ, Huston JM, Miller E, Lin X, Sherry B, Kumar A, Larosa G, Newman W, ... Tracey KJ, et al. Role of HMGB1 in apoptosis-mediated sepsis lethality. The Journal of Experimental Medicine. 203: 1637-42. PMID 16818669 DOI: 10.1084/jem.20052203  0.8
2006 Huston JM, Ochani M, Rosas-Ballina M, Liao H, Ochani K, Pavlov VA, Gallowitsch-Puerta M, Ashok M, Czura CJ, Foxwell B, Tracey KJ, Ulloa L. Splenectomy inactivates the cholinergic antiinflammatory pathway during lethal endotoxemia and polymicrobial sepsis. The Journal of Experimental Medicine. 203: 1623-8. PMID 16785311 DOI: 10.1084/jem.20052362  0.8
2006 Goldstein RS, Gallowitsch-Puerta M, Yang L, Rosas-Ballina M, Huston JM, Czura CJ, Lee DC, Ward MF, Bruchfeld AN, Wang H, Lesser ML, Church AL, Litroff AH, Sama AE, Tracey KJ. Elevated high-mobility group box 1 levels in patients with cerebral and myocardial ischemia. Shock (Augusta, Ga.). 25: 571-4. PMID 16721263 DOI: 10.1097/01.shk.0000209540.99176.72  0.8
2006 Pavlov VA, Ochani M, Gallowitsch-Puerta M, Ochani K, Huston JM, Czura CJ, Al-Abed Y, Tracey KJ. Central muscarinic cholinergic regulation of the systemic inflammatory response during endotoxemia. Proceedings of the National Academy of Sciences of the United States of America. 103: 5219-23. PMID 16549778 DOI: 10.1073/pnas.0600506103  0.8
2005 Yang H, Wang H, Czura CJ, Tracey KJ. The cytokine activity of HMGB1. Journal of Leukocyte Biology. 78: 1-8. PMID 15734795 DOI: 10.1189/jlb.1104648  0.8
2005 Chen G, Li J, Qiang X, Czura CJ, Ochani M, Ochani K, Ulloa L, Yang H, Tracey KJ, Wang P, Sama AE, Wang H. Suppression of HMGB1 release by stearoyl lysophosphatidylcholine:an additional mechanism for its therapeutic effects in experimental sepsis. Journal of Lipid Research. 46: 623-7. PMID 15687351 DOI: 10.1194/jlr.C400018-JLR200  0.8
2005 Czura CJ, Tracey KJ. Autonomic neural regulation of immunity. Journal of Internal Medicine. 257: 156-66. PMID 15656874 DOI: 10.1111/j.1365-2796.2004.01442.x  0.8
2004 Chen G, Chen DZ, Li J, Czura CJ, Tracey KJ, Sama AE, Wang H. Pathogenic role of HMGB1 in SARS? Medical Hypotheses. 63: 691-5. PMID 15325019 DOI: 10.1016/j.mehy.2004.01.037  0.8
2004 Li J, Wang H, Mason JM, Levine J, Yu M, Ulloa L, Czura CJ, Tracey KJ, Yang H. Recombinant HMGB1 with cytokine-stimulating activity. Journal of Immunological Methods. 289: 211-23. PMID 15251426 DOI: 10.1016/j.jim.2004.04.019  0.8
2004 Czura CJ, Yang H, Amella CA, Tracey KJ. HMGB1 in the immunology of sepsis (not septic shock) and arthritis. Advances in Immunology. 84: 181-200. PMID 15246253 DOI: 10.1016/S0065-2776(04)84005-7  0.8
2004 Wang H, Czura CJ, Tracey KJ. Lipid unites disparate syndromes of sepsis. Nature Medicine. 10: 124-5. PMID 14760415 DOI: 10.1038/nm0204-124  0.8
2004 Yang H, Ochani M, Li J, Qiang X, Tanovic M, Harris HE, Susarla SM, Ulloa L, Wang H, DiRaimo R, Czura CJ, Wang H, Roth J, Warren HS, Fink MP, ... ... Tracey KJ, et al. Reversing established sepsis with antagonists of endogenous high-mobility group box 1. Proceedings of the National Academy of Sciences of the United States of America. 101: 296-301. PMID 14695889 DOI: 10.1073/pnas.2434651100  0.44
2003 Czura CJ, Friedman SG, Tracey KJ. Neural inhibition of inflammation: the cholinergic anti-inflammatory pathway. Journal of Endotoxin Research. 9: 409-13. PMID 14733730 DOI: 10.1179/096805103225002755  0.8
2003 Pavlov VA, Wang H, Czura CJ, Friedman SG, Tracey KJ. The cholinergic anti-inflammatory pathway: a missing link in neuroimmunomodulation. Molecular Medicine (Cambridge, Mass.). 9: 125-34. PMID 14571320  0.8
2003 Czura CJ, Yang H, Tracey KJ. High mobility group box-1 as a therapeutic target downstream of tumor necrosis factor. The Journal of Infectious Diseases. 187: S391-6. PMID 12792856 DOI: 10.1086/374753  0.8
2003 Li J, Kokkola R, Tabibzadeh S, Yang R, Ochani M, Qiang X, Harris HE, Czura CJ, Wang H, Ulloa L, Warren HS, Moldawer LL, Fink MP, Andersson U, Tracey KJ, et al. Structural basis for the proinflammatory cytokine activity of high mobility group box 1 Molecular Medicine. 9: 37-45. PMID 12765338  0.44
2003 Friedman SG, Czura CJ, Tracey KJ. The gesture life of high mobility group box 1. Current Opinion in Clinical Nutrition and Metabolic Care. 6: 283-7. PMID 12690260 DOI: 10.1097/01.mco.0000068966.34812.b9  0.8
2003 Czura CJ, Tracey KJ. Targeting high mobility group box 1 as a late-acting mediator of inflammation. Critical Care Medicine. 31: S46-50. PMID 12544976 DOI: 10.1097/01.CCM.0000045030.74783.76  0.8
2003 Wang H, Yu M, Ochani M, Amelia CA, Tanovic M, Susarla S, Li JH, Yang N, Ulloa L, Al-Abed Y, Czura CJ, Tracey KJ. Nicotinic acetylcholine receptor α7 subunit is an essential regulator of inflammation Nature. 421: 384-388. PMID 12508119 DOI: 10.1038/nature01339  0.44
2002 Yang H, Wang H, Czura CJ, Tracey KJ. HMGB1 as a cytokine and therapeutic target. Journal of Endotoxin Research. 8: 469-72. PMID 12697092 DOI: 10.1179/096805102125001091  0.8
2002 Bernik TR, Friedman SG, Ochani M, DiRaimo R, Susarla S, Czura CJ, Tracey KJ, Watkins MT, Fantini GA. Cholinergic antiinflammatory pathway inhibition of tumor necrosis factor during ischemia reperfusion Journal of Vascular Surgery. 36: 1231-1236. PMID 12469056 DOI: 10.1067/mva.2002.129643  0.44
2002 Ulloa L, Ochani M, Yang H, Tanovic M, Halperin D, Yang R, Czura CJ, Fink MP, Tracey KJ. Ethyl pyruvate prevents lethality in mice with established lethal sepsis and systemic inflammation. Proceedings of the National Academy of Sciences of the United States of America. 99: 12351-6. PMID 12209006 DOI: 10.1073/pnas.192222999  0.8
2002 Bernik TR, Friedman SG, Ochani M, DiRaimo R, Ulloa L, Yang H, Sudan S, Czura CJ, Ivanova SM, Tracey KJ. Pharmacological stimulation of the cholinergic antiinflammatory pathway. The Journal of Experimental Medicine. 195: 781-8. PMID 11901203  0.8
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