| Year |
Citation |
Score |
| 2023 |
Chen Z, Liu X, Kawakami M, Liu X, Baker A, Bhatawadekar A, Tyutyunyk-Massey L, Narayan K, Dmitrovsky E. CDK2 inhibition disorders centrosome stoichiometry and alters cellular outcomes in aneuploid cancer cells. Cancer Biology & Therapy. 24: 2279241. PMID 38031910 DOI: 10.1080/15384047.2023.2279241 |
0.378 |
|
| 2023 |
Wei CH, Huang L, Kreh B, Liu X, Tyutyunyk-Massey L, Kawakami M, Chen Z, Shi M, Kozlov S, Chan KC, Andresson T, Carrington M, Vuligonda V, Sanders ME, Horowitz A, ... ... Dmitrovsky E, et al. A novel retinoic acid receptor-γ agonist antagonizes immune checkpoint resistance in lung cancers by altering the tumor immune microenvironment. Scientific Reports. 13: 14907. PMID 37689790 DOI: 10.1038/s41598-023-41690-5 |
0.364 |
|
| 2022 |
Chen Z, Zheng L, Chen Y, Liu X, Kawakami M, Mustachio LM, Roszik J, Ferry-Galow KV, Parchment RE, Liu X, Andresson T, Duncan G, Kurie JM, Rodriguez-Canales J, Liu X, ... Dmitrovsky E, et al. Loss of ubiquitin-specific peptidase 18 destabilizes 14-3-3ζ protein and represses lung cancer metastasis. Cancer Biology & Therapy. 23: 265-280. PMID 35387560 DOI: 10.1080/15384047.2022.2054242 |
0.449 |
|
| 2020 |
Liu X, Lu Y, Chen Z, Liu X, Hu W, Zheng L, Chen Y, Kurie JM, Shi M, Mustachio LM, Andresson T, Fox S, Roszik J, Kawakami M, Freemantle S, ... Dmitrovsky E, et al. The Ubiquitin Specific Protease USP18 Promotes Lipolysis, Fatty Acid Oxidation and Lung Cancer Growth. Molecular Cancer Research : McR. PMID 33380466 DOI: 10.1158/1541-7786.MCR-20-0579 |
0.369 |
|
| 2020 |
Kawakami M, Mustachio LM, Chen Y, Chen Z, Liu X, Wei CH, Roszik J, Kittai AS, Danilov AV, Zhang X, Fang B, Wang J, Heymach JV, Tyutyunyk-Massey L, Freemantle SJ, ... ... Dmitrovsky E, et al. A Novel CDK2/9 Inhibitor CYC065 Causes Anaphase Catastrophe and Represses Proliferation, Tumorigenesis and Metastasis in Aneuploid Cancers. Molecular Cancer Therapeutics. PMID 33277443 DOI: 10.1158/1535-7163.MCT-19-0987 |
0.462 |
|
| 2020 |
Dmitrovsky E, Kawakami M, Liu XI, Freemantle SJ, Kurie JM. TRIGGERING ANAPHASE CATASTROPHE TO COMBAT ANEUPLOID CANCERS. Transactions of the American Clinical and Climatological Association. 131: 82-94. PMID 32675848 |
0.399 |
|
| 2020 |
Liu X, Lu Y, Chen Z, Liu X, Hu W, Zheng L, Chen Y, Shi M, Mustachio L, Roszik J, Kawakami M, Freemantle S, Dmitrovsky E. Abstract 2547: USP18 promotes lipolysis, fatty acid oxidation and lung cancer growth Cancer Research. 80: 2547-2547. DOI: 10.1158/1538-7445.Am2020-2547 |
0.532 |
|
| 2019 |
Zheng L, Chen Z, Kawakami M, Chen Y, Roszik J, Mustachio LM, Kurie JM, Villalobos P, Lu W, Behren C, Mino B, Solis LM, Silvester J, Thu KL, Cescon DW, ... ... Dmitrovsky E, et al. Threonine Tyrosine Kinase Inhibition Eliminates Lung Cancers by Augmenting Apoptosis and Polyploidy. Molecular Cancer Therapeutics. PMID 31358662 DOI: 10.1158/1535-7163.Mct-18-0864 |
0.466 |
|
| 2019 |
Chen L, Diao L, Yi X, Rodriguez BL, Li Y, Villalobos P, Cascone T, Liu X, Tan L, Lorenzi P, Fradette J, Peng D, Skoulidis F, Fan Y, Rodriguez-Canales J, ... ... Dmitrovsky E, et al. Abstract A059: Tackling the tumor microenvironment with CD38 blockade to enhance cancer immunotherapy Cancer Immunology Research. 7. DOI: 10.1158/2326-6074.Cricimteatiaacr18-A059 |
0.394 |
|
| 2019 |
Chen Z, Zheng L, Chen Y, Kawakami M, Mustachio L, Roszik J, Liu X, Kurie J, Liu X, Dmitrovsky E. Abstract 170: Loss of the ubiquitin-specific peptidase 18 (USP18) reduces lung cancer metastasis Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-170 |
0.469 |
|
| 2018 |
Kawakami M, Liu X, Dmitrovsky E. New Cell Cycle Inhibitors Target Aneuploidy in Cancer Therapy. Annual Review of Pharmacology and Toxicology. PMID 30110577 DOI: 10.1146/annurev-pharmtox-010818-021649 |
0.313 |
|
| 2018 |
Kawakami M, Mustachio LM, Liu X, Dmitrovsky E. Engaging Anaphase Catastrophe Mechanisms to Eradicate Aneuploid Cancers. Molecular Cancer Therapeutics. PMID 29559545 DOI: 10.1158/1535-7163.MCT-17-1108 |
0.423 |
|
| 2018 |
Kawakami M, Mustachio LM, Zheng L, Chen Y, Rodriguez-Canales J, Mino B, Kurie JM, Roszik J, Villalobos PA, Thu KL, Silvester J, Cescon DW, Wistuba II, Mak TW, Liu X, ... Dmitrovsky E, et al. Polo-like kinase 4 inhibition produces polyploidy and apoptotic death of lung cancers. Proceedings of the National Academy of Sciences of the United States of America. PMID 29434041 DOI: 10.1073/Pnas.1719760115 |
0.548 |
|
| 2018 |
Mustachio LM, Lu Y, Kawakami M, Roszik J, Freemantle SJ, Liu X, Dmitrovsky E. Evidence for the ISG15-Specific Deubiquitinase USP18 as an Antineoplastic Target. Cancer Research. PMID 29343520 DOI: 10.1158/0008-5472.Can-17-1752 |
0.513 |
|
| 2017 |
Yim CY, Bikorimana E, Khan E, Warzecha JM, Shin L, Rodriguez J, Dmitrovsky E, Freemantle SJ, Spinella MJ. G0S2 represses PI3K/mTOR signaling and increases sensitivity to PI3K/mTOR pathway inhibitors in breast cancer. Cell Cycle (Georgetown, Tex.). 1-10. PMID 28910567 DOI: 10.1080/15384101.2017.1371884 |
0.46 |
|
| 2017 |
Sepesi B, Gold KA, Correa AM, Heymach JV, Vaporciyan AA, Roszik J, Dmitrovsky E, Liu X. The Influence of Body Mass Index on Overall Survival Following Surgical Resection of Non-Small Cell Lung Cancer. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. PMID 28552766 DOI: 10.1016/j.jtho.2017.05.010 |
0.321 |
|
| 2017 |
Kawakami M, Mustachio LM, Rodriguez-Canales J, Mino B, Roszik J, Tong P, Wang J, Lee JJ, Myung JH, Heymach JV, Johnson FM, Hong S, Zheng L, Hu S, Villalobos PA, ... ... Dmitrovsky E, et al. Next-Generation CDK2/9 Inhibitors and Anaphase Catastrophe in Lung Cancer. Journal of the National Cancer Institute. 109. PMID 28376145 DOI: 10.1093/Jnci/Djw297 |
0.495 |
|
| 2017 |
Mustachio LM, Lu Y, Tafe LJ, Memoli V, Rodriguez-Canales J, Mino B, Villalobos PA, Wistuba I, Katayama H, Hanash SM, Roszik J, Kawakami M, Cho KJ, Hancock JF, Chinyengetere F, ... ... Dmitrovsky E, et al. Deubiquitinase USP18 Loss Mislocalizes and Destabilizes KRAS in Lung Cancer. Molecular Cancer Research : McR. PMID 28242811 DOI: 10.1158/1541-7786.Mcr-16-0369 |
0.84 |
|
| 2017 |
Liu X, Roszik J, Karakami M, Sanders M, Chandraratna R, Dmitrovsky E, Dragnev KH. IRX4204 in combination with erlotinib to target distinct pathways in lung cancer cells. Journal of Clinical Oncology. 35: e14095-e14095. DOI: 10.1200/JCO.2017.35.15_SUPPL.E14095 |
0.515 |
|
| 2017 |
Zheng L, Mustachio L, Chen Y, Liu X, Roszik J, Kurie J, Dmitrovsky E. Abstract 4855: Loss of USP18 represses invasion and metastasis of lung cancer Cancer Research. 77: 4855-4855. DOI: 10.1158/1538-7445.Am2017-4855 |
0.453 |
|
| 2016 |
Mustachio LM, Kawakami M, Lu Y, Rodriguez-Canales J, Mino B, Behrens C, Wistuba I, Bota-Rabassedas N, Yu J, Lee JJ, Roszik J, Zheng L, Liu X, Freemantle SJ, Dmitrovsky E. The ISG15-specific protease USP18 regulates stability of PTEN. Oncotarget. PMID 27980214 DOI: 10.18632/Oncotarget.13914 |
0.537 |
|
| 2016 |
Danilov AV, Hu S, Orr B, Godek K, Mustachio LM, Sekula D, Liu X, Kawakami M, Johnson FM, Compton DA, Freemantle SJ, Dmitrovsky E. Dinaciclib Induces Anaphase Catastrophe in Lung Cancer Cells via Inhibition of Cyclin Dependent Kinases 1 and 2. Molecular Cancer Therapeutics. PMID 27550941 DOI: 10.1158/1535-7163.Mct-16-0127 |
0.564 |
|
| 2016 |
Uray IP, Dmitrovsky E, Brown PH. Retinoids and rexinoids in cancer prevention: from laboratory to clinic. Seminars in Oncology. 43: 49-64. PMID 26970124 DOI: 10.1053/j.seminoncol.2015.09.002 |
0.346 |
|
| 2016 |
Yim CY, Sekula D, Hever-Jardine MP, Liu X, Warzecha JM, Tam J, Freemantle SJ, Dmitrovsky E, Spinella MJ. G0S2 suppresses oncogenic transformation by repressing a Myc-regulated transcriptional program. Cancer Research. PMID 26837760 DOI: 10.1158/0008-5472.Can-15-2265 |
0.32 |
|
| 2015 |
Chinyengetere F, Sekula DJ, Lu Y, Giustini AJ, Sanglikar A, Kawakami M, Ma T, Burkett SS, Eisenberg BL, Wells WA, Hoopes PJ, Demicco EG, Lazar AJ, Torres KE, Memoli V, ... ... Dmitrovsky E, et al. Mice null for the deubiquitinase USP18 spontaneously develop leiomyosarcomas. Bmc Cancer. 15: 886. PMID 26555296 DOI: 10.1186/S12885-015-1883-8 |
0.792 |
|
| 2015 |
Myung JH, Roengvoraphoj M, Tam KA, Ma T, Memoli VA, Dmitrovsky E, Freemantle SJ, Hong S. Effective Capture of Circulating Tumor Cells from a Transgenic Mouse Lung Cancer Model Using Dendrimer Surfaces Immobilized with Anti-EGFR. Analytical Chemistry. 87: 10096-102. PMID 26312815 DOI: 10.1021/Acs.Analchem.5B02766 |
0.514 |
|
| 2015 |
Hu S, Lu Y, Orr B, Godek K, Mustachio LM, Kawakami M, Sekula D, Compton DA, Freemantle S, Dmitrovsky E. Specific CP110 Phosphorylation Sites Mediate Anaphase Catastrophe after CDK2 Inhibition: Evidence for Cooperation with USP33 Knockdown. Molecular Cancer Therapeutics. PMID 26304236 DOI: 10.1158/1535-7163.Mct-15-0443 |
0.524 |
|
| 2015 |
Hu S, Danilov AV, Godek K, Orr B, Tafe LJ, Rodriguez-Canales J, Behrens C, Mino B, Moran CA, Memoli VA, Mustachio LM, Galimberti F, Ravi S, DeCastro A, Lu Y, ... ... Dmitrovsky E, et al. CDK2 Inhibition Causes Anaphase Catastrophe in Lung Cancer through the Centrosomal Protein CP110. Cancer Research. 75: 2029-38. PMID 25808870 DOI: 10.1158/0008-5472.Can-14-1494 |
0.797 |
|
| 2015 |
Kawakami M, Mustachio LM, Liu X, Hu S, Lu Y, Sekula D, Freemantle S, Dmitrovsky E. Abstract 942: Novel CDK2/9 inhibitor has antineoplastic activity in lung cancer by inducing anaphase catastrophe Cancer Research. 75: 942-942. DOI: 10.1158/1538-7445.Am2015-942 |
0.493 |
|
| 2015 |
Yim CY, Sekula DJ, Freemantle SJ, Dmitrovsky E, Spinella MJ. Abstract 2026: G0S2 functions as a tumor suppressor gene through inhibition of c-Myc Cancer Research. 75: 2026-2026. DOI: 10.1158/1538-7445.Am2015-2026 |
0.479 |
|
| 2015 |
Myung JH, Roengvoraphoj M, Tam KA, Ma T, Memoli VA, Dmitrovsky E, Freemantle SJ, Hong S. Effective Capture of Circulating Tumor Cells from a Transgenic Mouse Lung Cancer Model Using Dendrimer Surfaces Immobilized with Anti-EGFR Analytical Chemistry. 87: 10096-10102. DOI: 10.1021/acs.analchem.5b02766 |
0.394 |
|
| 2014 |
Ma T, Lopez-Aguiar AG, Li A, Lu Y, Sekula D, Nattie EE, Freemantle S, Dmitrovsky E. Mice lacking G0S2 are lean and cold-tolerant. Cancer Biology & Therapy. 15: 643-50. PMID 24556704 DOI: 10.4161/Cbt.28251 |
0.311 |
|
| 2014 |
Busch AM, Galimberti F, Nehls KE, Roengvoraphoj M, Sekula D, Li B, Guo Y, Direnzo J, Fiering SN, Spinella MJ, Robbins DJ, Memoli VA, Freemantle SJ, Dmitrovsky E. All-trans-retinoic acid antagonizes the Hedgehog pathway by inducing patched. Cancer Biology & Therapy. 15: 463-72. PMID 24496080 DOI: 10.4161/Cbt.27821 |
0.823 |
|
| 2014 |
Hu S, Danilov AV, Godek KM, Orr B, Tafe LJ, Memoli VA, Galimberti F, Ravi S, DeCastro AJ, Lu Y, Mustachio LM, Sekula DJ, Andrew AS, Freemantle SJ, Compton DA, ... Dmitrovsky E, et al. Abstract 4549: CDK2 inhibition causes anaphase catastrophe through the centrosomal protein CP110 Cancer Research. 74: 4549-4549. DOI: 10.1158/1538-7445.Am2014-4549 |
0.793 |
|
| 2014 |
Mustachio LM, Chinyengetere F, Lu Y, Hu S, Kawakami M, Tafe LJ, Danilov A, Sekula DJ, Ma T, Freemantle SJ, Dmitrovsky E. Abstract 1782: The ubiquitin protease UBP43 is a target for KRAS mutant lung cancers Cancer Research. 74: 1782-1782. DOI: 10.1158/1538-7445.Am2014-1782 |
0.844 |
|
| 2013 |
Aoyama K, Saha A, Tolar J, Riddle MJ, Veenstra RG, Taylor PA, Blomhoff R, Panoskaltsis-Mortari A, Klebanoff CA, Socié G, Munn DH, Murphy WJ, Serody JS, Fulton LM, Teshima T, ... ... Dmitrovsky E, et al. Inhibiting retinoic acid signaling ameliorates graft-versus-host disease by modifying T-cell differentiation and intestinal migration. Blood. 122: 2125-34. PMID 23814022 DOI: 10.1182/Blood-2012-11-470252 |
0.338 |
|
| 2013 |
Ma T, Galimberti F, Erkmen CP, Memoli V, Chinyengetere F, Sempere L, Beumer JH, Anyang BN, Nugent W, Johnstone D, Tsongalis GJ, Kurie JM, Li H, Direnzo J, Guo Y, ... ... Dmitrovsky E, et al. Comparing histone deacetylase inhibitor responses in genetically engineered mouse lung cancer models and a window of opportunity trial in patients with lung cancer. Molecular Cancer Therapeutics. 12: 1545-55. PMID 23686769 DOI: 10.1158/1535-7163.Mct-12-0933 |
0.84 |
|
| 2013 |
Busch AM, Johnson KC, Stan RV, Sanglikar A, Ahmed Y, Dmitrovsky E, Freemantle SJ. Evidence for tankyrases as antineoplastic targets in lung cancer. Bmc Cancer. 13: 211. PMID 23621985 DOI: 10.1186/1471-2407-13-211 |
0.847 |
|
| 2013 |
Ma T, Dong JP, Sekula DJ, Fei DL, Lamph WW, Henderson M, Lu Y, Blumen S, Freemantle SJ, Dmitrovsky E. Repression of exogenous gene expression by the retinoic acid target gene G0S2. International Journal of Oncology. 42: 1743-53. PMID 23546556 DOI: 10.3892/Ijo.2013.1876 |
0.406 |
|
| 2013 |
Rodriguez-Blanco J, Schilling NS, Tokhunts R, Giambelli C, Long J, Liang Fei D, Singh S, Black KE, Wang Z, Galimberti F, Bejarano PA, Elliot S, Glassberg MK, Nguyen DM, Lockwood WW, ... ... Dmitrovsky E, et al. The hedgehog processing pathway is required for NSCLC growth and survival. Oncogene. 32: 2335-45. PMID 22733134 DOI: 10.1038/Onc.2012.243 |
0.785 |
|
| 2013 |
Lu Y, Mustachio LM, Chinyengetere F, Yang W, Ma T, Dong J, Sekula DJ, Freemantle SJ, Dmitrovsky E. Abstract 4125: The retinoid-induced G0S2 protein undergoes ISG15ylation and destabilization. Cancer Research. 73: 4125-4125. DOI: 10.1158/1538-7445.Am2013-4125 |
0.808 |
|
| 2013 |
Chinyengetere F, Giustini A, Sekula D, Freemantle S, Memoli VA, Hoopes PJ, Dmitrovsky E. Abstract 1089: Spontaneous formation of sarcomas in Usp18 knockout mice. Cancer Research. 73: 1089-1089. DOI: 10.1158/1538-7445.Am2013-1089 |
0.808 |
|
| 2013 |
Dragnev K, Beumer J, Anyang B, Ma T, Galimberti F, Erkmen C, Nugent W, Rigas J, Abraham K, Johnstone D, Memoli V, Dmitrovsky E. A Proof-of-Principle Histone Deacetylase Inhibitor Trial in Resectable Aerodigestive Tract Cancer: Intratumoral Drug Levels and Biomarker Responses Annals of Oncology. 24: i7. DOI: 10.1093/Annonc/Mdt042.14 |
0.69 |
|
| 2012 |
Ma T, Fuld AD, Rigas JR, Hagey AE, Gordon GB, Dmitrovsky E, Dragnev KH. A phase I trial and in vitro studies combining ABT-751 with carboplatin in previously treated non-small cell lung cancer patients. Chemotherapy. 58: 321-9. PMID 23147218 DOI: 10.1159/000343165 |
0.498 |
|
| 2012 |
Galimberti F, Busch AM, Chinyengetere F, Ma T, Sekula D, Memoli VA, Dragnev KH, Liu F, Johnson KC, Guo Y, Freemantle SJ, Andrew AS, Greninger P, Robbins DJ, Settleman J, ... ... Dmitrovsky E, et al. Response to inhibition of smoothened in diverse epithelial cancer cells that lack smoothened or patched 1 mutations. International Journal of Oncology. 41: 1751-61. PMID 22923130 DOI: 10.3892/Ijo.2012.1599 |
0.832 |
|
| 2012 |
Guo Y, Pino-Lagos K, Ahonen CA, Bennett KA, Wang J, Napoli JL, Blomhoff R, Sockanathan S, Chandraratna RA, Dmitrovsky E, Turk MJ, Noelle RJ. A retinoic acid--rich tumor microenvironment provides clonal survival cues for tumor-specific CD8(+) T cells. Cancer Research. 72: 5230-9. PMID 22902413 DOI: 10.1158/0008-5472.Can-12-1727 |
0.387 |
|
| 2012 |
Guo Y, Chinyengetere F, Dolinko AV, Lopez-Aguiar A, Lu Y, Galimberti F, Ma T, Feng Q, Sekula D, Freemantle SJ, Andrew AS, Memoli V, Dmitrovsky E. Evidence for the ubiquitin protease UBP43 as an antineoplastic target. Molecular Cancer Therapeutics. 11: 1968-77. PMID 22752428 DOI: 10.1158/1535-7163.Mct-12-0248 |
0.835 |
|
| 2012 |
Roengvoraphoj M, Guo Y, Ma T, Stan RV, Obad S, Kauppinen S, Dmitrovsky E, Freemantle SJ. Therapeutic targeting of microRNA-31 in lung cancer. Journal of Clinical Oncology. 30: e13567-e13567. DOI: 10.1200/Jco.2012.30.15_Suppl.E13567 |
0.438 |
|
| 2012 |
Dragnev KH, Beumer JH, Anyang B, Ma T, Galimberti F, Erkmen CP, Nugent W, Rigas JR, Abraham K, Johnstone D, Memoli V, Dmitrovsky E. Vorinostat (V) intratumoral levels and biomarker response in a window of opportunity trial in patients with resectable aerodigestive tract cancer. Journal of Clinical Oncology. 30: 7022-7022. DOI: 10.1200/Jco.2012.30.15_Suppl.7022 |
0.721 |
|
| 2012 |
Busch AM, Johnson KC, Tacchelly O, Wang Z, Ahmed YF, Dmitrovsky E, Freemantle SJ. Abstract 973: Tankyrase inhibition represses Wnt signaling and lung cancer growth Cancer Research. 72: 973-973. DOI: 10.1158/1538-7445.Am2012-973 |
0.845 |
|
| 2011 |
Dragnev KH, Ma T, Galimberti F, Erkmen CP, Memoli V, Nugent W, Rigas JR, Johnstone D, Frandsen A, Simeone S, Czum J, Li H, DiRenzo J, Freemantle S, Dmitrovsky E. A window-of-opportunity trial of vorinostat (V) in patients with resectable non-small cell lung cancer (NSCLC). Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 7062. PMID 28020374 DOI: 10.1200/Jco.2011.29.15_Suppl.7062 |
0.774 |
|
| 2011 |
Pino-Lagos K, Guo Y, Brown C, Alexander MP, Elgueta R, Bennett KA, De Vries V, Nowak E, Blomhoff R, Sockanathan S, Chandraratna RA, Dmitrovsky E, Noelle RJ. A retinoic acid-dependent checkpoint in the development of CD4+ T cell-mediated immunity. The Journal of Experimental Medicine. 208: 1767-75. PMID 21859847 DOI: 10.1084/Jem.20102358 |
0.347 |
|
| 2011 |
Dragnev KH, Ma T, Cyrus J, Galimberti F, Memoli V, Busch AM, Tsongalis GJ, Seltzer M, Johnstone D, Erkmen CP, Nugent W, Rigas JR, Liu X, Freemantle SJ, Kurie JM, ... ... Dmitrovsky E, et al. Bexarotene plus erlotinib suppress lung carcinogenesis independent of KRAS mutations in two clinical trials and transgenic models. Cancer Prevention Research (Philadelphia, Pa.). 4: 818-28. PMID 21636548 DOI: 10.1158/1940-6207.Capr-10-0376 |
0.828 |
|
| 2011 |
Singh S, Wang Z, Liang Fei D, Black KE, Goetz JA, Tokhunts R, Giambelli C, Rodriguez-Blanco J, Long J, Lee E, Briegel KJ, Bejarano PA, Dmitrovsky E, Capobianco AJ, Robbins DJ. Hedgehog-producing cancer cells respond to and require autocrine Hedgehog activity. Cancer Research. 71: 4454-63. PMID 21565978 DOI: 10.1158/0008-5472.Can-10-2313 |
0.826 |
|
| 2011 |
Liu X, Sempere LF, Guo Y, Korc M, Kauppinen S, Freemantle SJ, Dmitrovsky E. Involvement of microRNAs in lung cancer biology and therapy. Translational Research : the Journal of Laboratory and Clinical Medicine. 157: 200-8. PMID 21420030 DOI: 10.1016/J.Trsl.2011.01.001 |
0.455 |
|
| 2011 |
Galimberti F, Thompson SL, Ravi S, Compton DA, Dmitrovsky E. Anaphase catastrophe is a target for cancer therapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 1218-22. PMID 21288923 DOI: 10.1158/1078-0432.Ccr-10-1178 |
0.742 |
|
| 2011 |
Dragnev KH, Ma T, Cyrus J, Galimberti F, Memoli V, Busch AM, Tsongalis GJ, Seltzer MA, Johnstone D, Erkmen CP, Nugent W, Rigas JR, Liu X, Freemantle SJ, Kurie JM, ... ... Dmitrovsky E, et al. Abstract LB-412: Combining bexarotene with erlotinib in window of opportunity and phase II trials causes lung cancer responses independent of KRAS mutations Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Lb-412 |
0.828 |
|
| 2011 |
Ma T, Galimberti F, Erkmen CP, Memoli V, Nugent W, Rigas J, Johnstone D, Li H, DiRenzo J, Freemantle S, Dragnev K, Dmitrovsky E. Abstract 342: Murine transgenic lung cancer models guide a proof of principle histone deacetylase inhibitor trial in lung cancer patients Cancer Research. 71: 342-342. DOI: 10.1158/1538-7445.Am2011-342 |
0.794 |
|
| 2011 |
Guo Y, Chinyengetere F, Dolinko AV, Lopez-Aguiar A, Galimberti F, Ma T, Feng Q, Andrew AS, Sekula D, Freemantle S, Memoli V, Dmitrovsky E. Abstract 1655: The ubiquitin protease UBP43 is a target for lung cancer therapy and prevention Cancer Research. 71: 1655-1655. DOI: 10.1158/1538-7445.Am2011-1655 |
0.847 |
|
| 2011 |
Galimberti F, Busch A, Chinyengetere F, Ma T, Sekula D, Memoli V, Dragnev K, Liu F, Andrew AS, Greninger P, Robbins D, Settleman J, Benes C, Dmitrovsky E. Abstract 1615: Gene expression profile predicts response to smoothened inhibitors in epithelial cancers Cancer Research. 71: 1615-1615. DOI: 10.1158/1538-7445.Am2011-1615 |
0.837 |
|
| 2010 |
Freemantle SJ, Dmitrovsky E. Cyclin E transgenic mice: discovery tools for lung cancer biology, therapy, and prevention. Cancer Prevention Research (Philadelphia, Pa.). 3: 1513-8. PMID 21149327 DOI: 10.1158/1940-6207.Capr-10-0297 |
0.547 |
|
| 2010 |
Guo Y, Dolinko AV, Chinyengetere F, Stanton B, Bomberger JM, Demidenko E, Zhou DC, Gallagher R, Ma T, Galimberti F, Liu X, Sekula D, Freemantle S, Dmitrovsky E. Blockade of the ubiquitin protease UBP43 destabilizes transcription factor PML/RARα and inhibits the growth of acute promyelocytic leukemia. Cancer Research. 70: 9875-85. PMID 20935222 DOI: 10.1158/0008-5472.Can-10-1100 |
0.81 |
|
| 2010 |
Liu X, Sempere LF, Ouyang H, Memoli VA, Andrew AS, Luo Y, Demidenko E, Korc M, Shi W, Preis M, Dragnev KH, Li H, Direnzo J, Bak M, Freemantle SJ, ... ... Dmitrovsky E, et al. MicroRNA-31 functions as an oncogenic microRNA in mouse and human lung cancer cells by repressing specific tumor suppressors. The Journal of Clinical Investigation. 120: 1298-309. PMID 20237410 DOI: 10.1172/Jci39566 |
0.429 |
|
| 2010 |
Galimberti F, Thompson SL, Liu X, Li H, Memoli V, Green SR, DiRenzo J, Greninger P, Sharma SV, Settleman J, Compton DA, Dmitrovsky E. Targeting the cyclin E-Cdk-2 complex represses lung cancer growth by triggering anaphase catastrophe. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 109-20. PMID 20028770 DOI: 10.1158/1078-0432.Ccr-09-2151 |
0.76 |
|
| 2010 |
Liu X, Sempere LF, Ouyang H, Memoli VA, Andrew AS, Luo Y, Demidenko E, Korc M, Shi W, Preis M, Dragnev KH, Liu H, DiRenzo J, Bak M, Kauppinen S, ... ... Dmitrovsky E, et al. Abstract 5698: MicroRNA-31 acts as an oncomir in lung cancer by repressing specific tumor suppressors Cancer Research. 70: 5698-5698. DOI: 10.1158/1538-7445.Am10-5698 |
0.429 |
|
| 2010 |
Beyrouthy MJ, Garner K, Hever MP, Freemantle SJ, Eastman A, Dmitrovsky E, Spinella MJ. Abstract 4273: DNA methyltransferase 3B mediates 5-aza-deoxycytidine hypersensitivity in cisplatin-sensitive and cisplatin-resistant pluripotent embryonal carcinoma cells Cancer Research. 70: 4273-4273. DOI: 10.1158/1538-7445.Am10-4273 |
0.445 |
|
| 2010 |
Guo Y, Dolinko A, Chinyengetere F, Bomberger J, Gallagher R, Ma T, Galimberti F, Liu X, Sekula D, Busch A, Freemantle S, Dmitrovsky E. Abstract 1594: Targeting UBP43 for repression destabilizes PML/RARα and inhibits acute promyelocytic leukemia growth Cancer Research. 70: 1594-1594. DOI: 10.1158/1538-7445.Am10-1594 |
0.813 |
|
| 2009 |
Beyrouthy MJ, Garner KM, Hever MP, Freemantle SJ, Eastman A, Dmitrovsky E, Spinella MJ. High DNA methyltransferase 3B expression mediates 5-aza-deoxycytidine hypersensitivity in testicular germ cell tumors. Cancer Research. 69: 9360-6. PMID 19951990 DOI: 10.1158/0008-5472.Can-09-1490 |
0.418 |
|
| 2009 |
Snow GE, Kasper AC, Busch AM, Schwarz E, Ewings KE, Bee T, Spinella MJ, Dmitrovsky E, Freemantle SJ. Wnt pathway reprogramming during human embryonal carcinoma differentiation and potential for therapeutic targeting. Bmc Cancer. 9: 383. PMID 19874621 DOI: 10.1186/1471-2407-9-383 |
0.782 |
|
| 2009 |
Sempere LF, Liu X, Dmitrovsky E. Tumor-suppressive microRNAs in Lung cancer: diagnostic and therapeutic opportunities. Thescientificworldjournal. 9: 626-8. PMID 19618089 DOI: 10.1100/Tsw.2009.88 |
0.512 |
|
| 2009 |
Liu X, Sempere LF, Galimberti F, Freemantle SJ, Black C, Dragnev KH, Yan M, Fiering S, Memoli V, Li H, Direnzo J, Korc M, Cole CN, Bak M, Kauppinen S, ... Dmitrovsky E, et al. Uncovering growth-Suppressive micro rNAs in lung cancer Clinical Cancer Research. 15: 1177-1183. PMID 19228723 DOI: 10.1158/1078-0432.Ccr-08-1355 |
0.734 |
|
| 2009 |
Freemantle SJ, Guo Y, Dmitrovsky E. Retinoid chemoprevention trials: cyclin D1 in the crosshairs. Cancer Prevention Research (Philadelphia, Pa.). 2: 3-6. PMID 19139010 DOI: 10.1158/1940-6207.Capr-08-0218 |
0.41 |
|
| 2009 |
Swift CB, Varela VA, Graves JT, Dmitrovsky E, Petty WJ. Abstract A208: Comparison of expression and function of two functional RARβ isoforms in human cancer: Clinical implications for the differential splicing of the RARβ gene Molecular Cancer Therapeutics. 8. DOI: 10.1158/1535-7163.Targ-09-A208 |
0.569 |
|
| 2008 |
Feng Q, Sekula D, Guo Y, Liu X, Black CC, Galimberti F, Shah SJ, Sempere LF, Memoli V, Andersen JB, Hassel BA, Dragnev K, Dmitrovsky E. UBE1L causes lung cancer growth suppression by targeting cyclin D1. Molecular Cancer Therapeutics. 7: 3780-8. PMID 19074853 DOI: 10.1158/1535-7163.Mct-08-0753 |
0.747 |
|
| 2008 |
Kitareewan S, Blumen S, Sekula D, Bissonnette RP, Lamph WW, Cui Q, Gallagher R, Dmitrovsky E. G0S2 is an all-trans-retinoic acid target gene. International Journal of Oncology. 33: 397-404. PMID 18636162 DOI: 10.3892/Ijo_00000021 |
0.446 |
|
| 2008 |
Liby K, Black CC, Royce DB, Williams CR, Risingsong R, Yore MM, Liu X, Honda T, Gribble GW, Lamph WW, Sporn TA, Dmitrovsky E, Sporn MB. The rexinoid LG100268 and the synthetic triterpenoid CDDO-methyl amide are more potent than erlotinib for prevention of mouse lung carcinogenesis Molecular Cancer Therapeutics. 7: 1251-1257. PMID 18483313 DOI: 10.1158/1535-7163.Mct-08-0023 |
0.445 |
|
| 2008 |
Shah SJ, Blumen S, Pitha-Rowe I, Kitareewan S, Freemantle SJ, Feng Q, Dmitrovsky E. UBE1L represses PML/RAR{alpha} by targeting the PML domain for ISG15ylation. Molecular Cancer Therapeutics. 7: 905-14. PMID 18413804 DOI: 10.1158/1535-7163.Mct-07-0515 |
0.803 |
|
| 2008 |
Dragnev KH, Rigas JR, Seltzer M, DiSalvo W, Simeone S, Johnstone D, Nugent W, Dmitrovsky E. A phase II clinical and PET study of erlotinib and bexarotene for heavily pretreated advanced non-small cell lung cancer (NSCLC) Journal of Clinical Oncology. 26: 19079-19079. DOI: 10.1200/JCO.2008.26.15_SUPPL.19079 |
0.349 |
|
| 2008 |
Liu X, Sempere L, Galimberti F, Freemantle S, Black C, Fiering S, Cole C, Dragnev K, Memoli V, Korc M, Li H, DiRenzo J, Bak M, Kauppinen S, Dmitrovsky E. Abstract A135: Uncovering tumor suppressive and oncogenic microRNAs in lung cancer Cancer Prevention Research. 1. DOI: 10.1158/1940-6207.Prev-08-A135 |
0.479 |
|
| 2007 |
Ma Y, Feng Q, Pitha-Rowe I, Kitareewan S, Dmitrovsky E. Gene profiling uncovers retinoid target genes. Methods in Molecular Biology (Clifton, N.J.). 383: 101-21. PMID 18217681 DOI: 10.1007/978-1-59745-335-6_7 |
0.834 |
|
| 2007 |
Freemantle SJ, Liu X, Feng Q, Galimberti F, Blumen S, Sekula D, Kitareewan S, Dragnev KH, Dmitrovsky E. Cyclin degradation for cancer therapy and chemoprevention. Journal of Cellular Biochemistry. 102: 869-77. PMID 17868090 DOI: 10.1002/Jcb.21519 |
0.755 |
|
| 2007 |
Liby K, Royce DB, Williams CR, Risingsong R, Yore MM, Honda T, Gribble GW, Dmitrovsky E, Sporn TA, Sporn MB. The synthetic triterpenoids CDDO-methyl ester and CDDO-ethyl amide prevent lung cancer induced by vinyl carbamate in A/J mice Cancer Research. 67: 2414-2419. PMID 17363558 DOI: 10.1158/0008-5472.Can-06-4534 |
0.495 |
|
| 2007 |
Dragnev KH, Petty WJ, Shah SJ, Lewis LD, Black CC, Memoli V, Nugent WC, Hermann T, Negro-Vilar A, Rigas JR, Dmitrovsky E. A proof-of-principle clinical trial of bexarotene in patients with non-small cell lung cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 1794-800. PMID 17363535 DOI: 10.1158/1078-0432.Ccr-06-1836 |
0.478 |
|
| 2007 |
Ma Y, Fiering S, Black C, Liu X, Yuan Z, Memoli VA, Robbins DJ, Bentley HA, Tsongalis GJ, Demidenko E, Freemantle SJ, Dmitrovsky E. Transgenic cyclin E triggers dysplasia and multiple pulmonary adenocarcinomas. Proceedings of the National Academy of Sciences of the United States of America. 104: 4089-94. PMID 17360482 DOI: 10.1073/Pnas.0606537104 |
0.694 |
|
| 2007 |
Dragnev KH, Feng Q, Ma Y, Shah SJ, Black C, Memoli V, Nugent W, Rigas JR, Kitareewan S, Freemantle S, Dmitrovsky E. Uncovering novel targets for cancer chemoprevention. Recent Results in Cancer Research. Fortschritte Der Krebsforschung. ProgrèS Dans Les Recherches Sur Le Cancer. 174: 235-43. PMID 17302201 DOI: 10.1016/S1359-6349(06)80508-2 |
0.478 |
|
| 2007 |
Freemantle SJ, Vaseva AV, Ewings KE, Bee T, Krizan KA, Kelley MR, Hattab EM, Memoli VA, Black CC, Spinella MJ, Dmitrovsky E. Repression of cyclin D1 as a target for germ cell tumors. International Journal of Oncology. 30: 333-40. PMID 17203214 DOI: 10.3892/Ijo.30.2.333 |
0.443 |
|
| 2007 |
Yuan Z, Goetz JA, Singh S, Ogden SK, Petty WJ, Black CC, Memoli VA, Dmitrovsky E, Robbins DJ. Frequent requirement of hedgehog signaling in non-small cell lung carcinoma. Oncogene. 26: 1046-55. PMID 16909105 DOI: 10.1038/Sj.Onc.1209860 |
0.701 |
|
| 2007 |
Dragnev KH, Rigas JR, Disalvo WM, Simeone SA, Williams I, Leahy T, Hagey AE, Gordon GB, Dmitrovsky E. P2-249: A Phase I Trial of ABT-751 and carboplatin in patients with previously treated non-small cell lung cancer Journal of Thoracic Oncology. 2: S671-S672. DOI: 10.1097/01.Jto.0000283957.06215.29 |
0.473 |
|
| 2006 |
Freemantle SJ, Dragnev KH, Dmitrovsky E. The retinoic acid paradox in cancer chemoprevention. Journal of the National Cancer Institute. 98: 426-7. PMID 16595769 DOI: 10.1093/Jnci/Djj116 |
0.379 |
|
| 2006 |
Dmitrovsky E, Dragnev K, Feng Q, Ma Y, Shah S, Black C, Memoli V, Nugent W, Rigas J, Sutisak K, Freemantle S. Uncovering novel targets for cancer chemoprevention European Journal of Cancer Supplements. 4: 38. DOI: 10.1016/S1359-6349(06)80508-2 |
0.304 |
|
| 2006 |
Sporn M, Liby K, Royce D, Risingson R, Williams C, Dmitrovsky E, Sporn T, Geissler K. 5 Chemoprevention as an approach to control of carcinoma of the lung and mesothelioma Lung Cancer. 54: S2. DOI: 10.1016/S0169-5002(07)70081-8 |
0.349 |
|
| 2005 |
Petty WJ, Dragnev KH, Black WC, Cole BF, Hammond S, Williams I, Dmitrovsky E, Rigas JR. Weekly paclitaxel, carboplatin, and bexarotene for the treatment of patients with advanced non-small cell lung cancer: Efficacy results from a phase I/II study. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 23: 7243. PMID 27944733 DOI: 10.1200/jco.2005.23.16_suppl.7243 |
0.339 |
|
| 2005 |
Dragnev KH, Petty WJ, Shah S, Carey MA, Disalvo WM, Williams I, Rigas JR, Dmitrovsky E. A phase I trial of erlotinib and bexarotene as a targeted combination therapy for aerodigestive tract cancers. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 23: 7093. PMID 27944555 DOI: 10.1200/jco.2005.23.16_suppl.7093 |
0.445 |
|
| 2005 |
Dragnev KH, Petty WJ, Shah S, Biddle A, Desai NB, Memoli V, Rigas JR, Dmitrovsky E. Bexarotene and erlotinib for aerodigestive tract cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 23: 8757-64. PMID 16314636 DOI: 10.1200/Jco.2005.01.9521 |
0.442 |
|
| 2005 |
Petty WJ, Li N, Biddle A, Bounds R, Nitkin C, Ma Y, Dragnev KH, Freemantle SJ, Dmitrovsky E. A novel retinoic acid receptor beta isoform and retinoid resistance in lung carcinogenesis. Journal of the National Cancer Institute. 97: 1645-51. PMID 16288117 DOI: 10.1093/Jnci/Dji371 |
0.407 |
|
| 2005 |
Giuliano CJ, Kerley-Hamilton JS, Bee T, Freemantle SJ, Manickaratnam R, Dmitrovsky E, Spinella MJ. Retinoic acid represses a cassette of candidate pluripotency chromosome 12p genes during induced loss of human embryonal carcinoma tumorigenicity. Biochimica Et Biophysica Acta. 1731: 48-56. PMID 16168501 DOI: 10.1016/J.Bbaexp.2005.08.006 |
0.419 |
|
| 2005 |
Ma Y, Feng Q, Sekula D, Diehl JA, Freemantle SJ, Dmitrovsky E. Retinoid targeting of different D-type cyclins through distinct chemopreventive mechanisms. Cancer Research. 65: 6476-83. PMID 16024653 DOI: 10.1158/0008-5472.Can-05-0370 |
0.347 |
|
| 2005 |
Dragnev KH, Petty WJ, Ma Y, Rigas JR, Dmitrovsky E. Nonclassical retinoids and lung carcinogenesis. Clinical Lung Cancer. 6: 237-44. PMID 15694016 DOI: 10.3816/Clc.2005.N.003 |
0.531 |
|
| 2005 |
Petty W, Dragnev KH, Memoli VA, Rigas JR, Johnstone D, Dmitrovsky E. PROOF-OF-PRINCIPLE CLINICAL TRIAL OF BEXAROTENE FOR THE TREATMENT OF NON-SMALL CELL LUNG CANCER Chest. 128: 312S. DOI: 10.1378/Chest.128.4_Meetingabstracts.312S |
0.486 |
|
| 2005 |
Hermann T, Dragnev KH, Rigas JR, Petty WJ, Dmitrovsky E, Negro-Vilar A, Lamph W. Microarray gene expression analysis reveals molecular activities of bexarotene in in vitro models of non-dmall vell lung cancer (NSCLC) and in tumors of NSCLC patients Journal of Clinical Oncology. 23: 7234-7234. DOI: 10.1200/jco.2005.23.16_suppl.7234 |
0.396 |
|
| 2005 |
Johnstone D, Dragnev K, Petty W, Nugent W, Memoli V, Black C, Lewis L, Negro-Vilar A, Rigas J, Dmitrovsky E. P-954 Preoperative bexarotene in patients with resectable non-smallcell lung cancer (NSCLC): A proof-of-principle study Lung Cancer. 49: S371. DOI: 10.1016/S0169-5002(05)81447-3 |
0.442 |
|
| 2005 |
Dragnev K, Petty W, Shah S, Carey M, DiSalvo W, Williams I, Rigas J, Dmitrovsky E. P-948 Bexarotene and erlotinib as an active targeted combination therapy for advanced aerodigestive tract cancer Lung Cancer. 49: S369. DOI: 10.1016/S0169-5002(05)81441-2 |
0.381 |
|
| 2005 |
Black C, Pitha-Rowe I, Kitareewan S, Dragnev K, Petty W, Rigas J, Dmitrovsky E, Memoli V. P-650 Expression of cyclin 131, cyclin E, EGFR, UBE1L and K167 inpaired benign and malignant lung tissues Lung Cancer. 49: S289. DOI: 10.1016/S0169-5002(05)81143-2 |
0.389 |
|
| 2005 |
Petty J, Dragnev K, Memoli V, Iwata K, Rigas J, Dmitrovsky E. P-105 Proof-of principle clinical trial uncovers cyclin D1 repression as a biomarker of erlotinib response Lung Cancer. 49: S141-S142. DOI: 10.1016/S0169-5002(05)80599-9 |
0.303 |
|
| 2004 |
Petty WJ, Dragnev KH, Memoli VA, Davis TH, Nugent WC, Williams IR, Iwata KK, Hamilton M, Rigas JR, Dmitrovsky E. Cyclin D1 repression as a marker of erlotinib response in aerodigestive tract cancers. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 22: 3093. PMID 28014792 DOI: 10.1200/jco.2004.22.14_suppl.3093 |
0.36 |
|
| 2004 |
Petty WJ, Dragnev KH, Memoli VA, Ma Y, Desai NB, Biddle A, Davis TH, Nugent WC, Memoli N, Hamilton M, Iwata KK, Rigas JR, Dmitrovsky E. Epidermal growth factor receptor tyrosine kinase inhibition represses cyclin D1 in aerodigestive tract cancers. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 7547-54. PMID 15569985 DOI: 10.1158/1078-0432.Ccr-04-1169 |
0.507 |
|
| 2004 |
Pitha-Rowe I, Petty WJ, Feng Q, Koza-Taylor PH, Dimattia DA, Pinder L, Dragnev KH, Memoli N, Memoli V, Turi T, Beebe J, Kitareewan S, Dmitrovsky E. Microarray analyses uncover UBE1L as a candidate target gene for lung cancer chemoprevention. Cancer Research. 64: 8109-15. PMID 15520223 DOI: 10.1158/0008-5472.Can-03-3938 |
0.855 |
|
| 2004 |
Dmitrovsky E. Fenretinide activates a distinct apoptotic pathway. Journal of the National Cancer Institute. 96: 1264-5. PMID 15339958 DOI: 10.1093/Jnci/Djh268 |
0.313 |
|
| 2004 |
Dragnev KH, Pitha-Rowe I, Ma Y, Petty WJ, Sekula D, Murphy B, Rendi M, Suh N, Desai NB, Sporn MB, Freemantle SJ, Dmitrovsky E. Specific chemopreventive agents trigger proteasomal degradation of G1 cyclins: implications for combination therapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 2570-7. PMID 15073138 DOI: 10.1158/1078-0432.Ccr-03-0271 |
0.799 |
|
| 2004 |
Sempere LF, Freemantle S, Pitha-Rowe I, Moss E, Dmitrovsky E, Ambros V. Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation. Genome Biology. 5: R13. PMID 15003116 DOI: 10.1186/Gb-2004-5-3-R13 |
0.766 |
|
| 2004 |
Pitha-Rowe I, Hassel BA, Dmitrovsky E. Involvement of UBE1L in ISG15 conjugation during retinoid-induced differentiation of acute promyelocytic leukemia. The Journal of Biological Chemistry. 279: 18178-87. PMID 14976209 DOI: 10.1074/Jbc.M309259200 |
0.825 |
|
| 2004 |
Dragnev KH, Petty WJ, Memoli V, Black W, Williams I, Rigas JR, Dmitrovsky E. A phase I/II study of bexarotene (B) and erlotinib (E): A novel targeted combination therapy for lung cancer and other aerodigestive tract (ADT) tumors Journal of Clinical Oncology. 22: 3092-3092. DOI: 10.1200/JCO.2004.22.90140.3092 |
0.331 |
|
| 2004 |
Dragnev K, Petty W, Davis T, Williams I, Rigas J, Dmitrovsky E. 372 A phase I/II trial of erlotinib and bexarotene in aerodigestive tract cancers European Journal of Cancer Supplements. 2: 112. DOI: 10.1016/S1359-6349(04)80379-3 |
0.327 |
|
| 2003 |
Freemantle SJ, Spinella MJ, Dmitrovsky E. Retinoids in cancer therapy and chemoprevention: promise meets resistance. Oncogene. 22: 7305-15. PMID 14576840 DOI: 10.1038/Sj.Onc.1206936 |
0.442 |
|
| 2003 |
Dragnev KH, Petty WJ, Dmitrovsky E. Retinoid targets in cancer therapy and chemoprevention. Cancer Biology & Therapy. 2: S150-6. PMID 14508093 DOI: 10.4161/Cbt.215 |
0.527 |
|
| 2003 |
Pitha-Rowe I, Petty WJ, Kitareewan S, Dmitrovsky E. Retinoid target genes in acute promyelocytic leukemia. Leukemia. 17: 1723-30. PMID 12970771 DOI: 10.1038/Sj.Leu.2403065 |
0.797 |
|
| 2003 |
Ma Y, Koza-Taylor PH, DiMattia DA, Hames L, Fu H, Dragnev KH, Turi T, Beebe JS, Freemantle SJ, Dmitrovsky E. Microarray analysis uncovers retinoid targets in human bronchial epithelial cells. Oncogene. 22: 4924-32. PMID 12894236 DOI: 10.1038/Sj.Onc.1206728 |
0.476 |
|
| 2003 |
Petty WJ, Dragnev KH, Dmitrovsky E. Cyclin D1 as a target for chemoprevention. Lung Cancer (Amsterdam, Netherlands). 41: S155-61. PMID 12867074 DOI: 10.1016/S0169-5002(03)00159-4 |
0.495 |
|
| 2003 |
Dragnev KH, Stover D, Dmitrovsky E. Lung cancer prevention: the guidelines. Chest. 123: 60S-71S. PMID 12527565 DOI: 10.1378/Chest.123.1_Suppl.60S |
0.494 |
|
| 2003 |
Hirsch FR, Bunn PA, Dmitrovsky E, Field JK, Franklin WA, Greenberg RE, Hansen HH, Henschke CI, Rigas JR, Smith RA, Toennesen P, Mulshine JL. IV international conference on prevention and early detection of lung cancer, Reykjavik, Iceland, August 9-12, 2001. Lung Cancer (Amsterdam, Netherlands). 37: 325-44. PMID 12234703 DOI: 10.1016/S0169-5002(02)00141-1 |
0.444 |
|
| 2002 |
Freemantle SJ, Portland HB, Ewings K, Dmitrovsky F, DiPetrillo K, Spinella MJ, Dmitrovsky E. Characterization and tissue-specific expression of human GSK-3-binding proteins FRAT1 and FRAT2. Gene. 291: 17-27. PMID 12095675 DOI: 10.1016/S0378-1119(02)00594-2 |
0.458 |
|
| 2002 |
Kitareewan S, Pitha-Rowe I, Sekula D, Lowrey CH, Nemeth MJ, Golub TR, Freemantle SJ, Dmitrovsky E. UBE1L is a retinoid target that triggers PML/RARalpha degradation and apoptosis in acute promyelocytic leukemia. Proceedings of the National Academy of Sciences of the United States of America. 99: 3806-11. PMID 11891284 DOI: 10.1073/Pnas.052011299 |
0.816 |
|
| 2002 |
Freemantle SJ, Dmitrovsky E. Clinical link between p53 and angiogenesis in lung cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 20: 883-4. PMID 11844804 DOI: 10.1200/Jco.2002.20.4.883 |
0.464 |
|
| 2002 |
Lonardo F, Dragnev KH, Freemantle SJ, Ma Y, Memoli N, Sekula D, Knauth EA, Beebe JS, Dmitrovsky E. Evidence for the epidermal growth factor receptor as a target for lung cancer prevention. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 8: 54-60. PMID 11801540 |
0.427 |
|
| 2001 |
Dragnev KH, Freemantle SJ, Spinella MJ, Dmitrovsky E. Cyclin proteolysis as a retinoid cancer prevention mechanism. Annals of the New York Academy of Sciences. 952: 13-22. PMID 11795432 DOI: 10.1111/J.1749-6632.2001.Tb02724.X |
0.476 |
|
| 2001 |
Curtin JC, Dragnev KH, Sekula D, Christie AJ, Dmitrovsky E, Spinella MJ. Retinoic acid activates p53 in human embryonal carcinoma through retinoid receptor-dependent stimulation of p53 transactivation function. Oncogene. 20: 2559-69. PMID 11420666 DOI: 10.1038/Sj.Onc.1204370 |
0.408 |
|
| 2001 |
Pitts JD, Sloboda RD, Dragnev KH, Dmitrovsky E, Mycek MA. Autofluorescence characteristics of immortalized and carcinogen-transformed human bronchial epithelial cells. Journal of Biomedical Optics. 6: 31-40. PMID 11178578 DOI: 10.1117/1.1333057 |
0.356 |
|
| 2000 |
Dragnev KH, Rigas JR, Dmitrovsky E. The retinoids and cancer prevention mechanisms. The Oncologist. 5: 361-8. PMID 11040271 DOI: 10.1634/Theoncologist.5-5-361 |
0.48 |
|
| 2000 |
Spinella MJ, Dmitrovsky E. Aberrant retinoid signaling and breast cancer: the view from outside the nucleus. Journal of the National Cancer Institute. 92: 438-40. PMID 10716952 DOI: 10.1093/Jnci/92.6.438 |
0.325 |
|
| 1999 |
Kitareewan S, Spinella MJ, Allopenna J, Reczek PR, Dmitrovsky E. 4HPR triggers apoptosis but not differentiation in retinoid sensitive and resistant human embryonal carcinoma cells through an RARgamma independent pathway. Oncogene. 18: 5747-55. PMID 10523855 DOI: 10.1038/Sj.Onc.1202981 |
0.429 |
|
| 1999 |
Hromas R, Ye H, Spinella M, Dmitrovsky E, Xu D, Costa RH. Genesis, a Winged Helix transcriptional repressor, has embryonic expression limited to the neural crest, and stimulates proliferation in vitro in a neural development model. Cell and Tissue Research. 297: 371-82. PMID 10460485 DOI: 10.1007/S004410051365 |
0.458 |
|
| 1999 |
Albanell J, Bosl GJ, Reuter VE, Engelhardt M, Franco S, Moore MA, Dmitrovsky E. Telomerase activity in germ cell cancers and mature teratomas. Journal of the National Cancer Institute. 91: 1321-6. PMID 10433622 DOI: 10.1093/Jnci/91.15.1321 |
0.438 |
|
| 1999 |
Spinella MJ, Freemantle SJ, Sekula D, Chang JH, Christie AJ, Dmitrovsky E. Retinoic acid promotes ubiquitination and proteolysis of cyclin D1 during induced tumor cell differentiation. The Journal of Biological Chemistry. 274: 22013-8. PMID 10419526 DOI: 10.1074/Jbc.274.31.22013 |
0.43 |
|
| 1999 |
Yang WL, Zeng YX, El-Deiry WS, Nason-Burchenal K, Dmitrovsky E, Chin KV. Transcriptional activation of the cyclin-dependent kinase inhibitor p21 by PML/RARα Molecular Cell Biology Research Communications. 1: 125-131. PMID 10356361 DOI: 10.1006/Mcbr.1999.0121 |
0.458 |
|
| 1999 |
Boyle JO, Langenfeld J, Lonardo F, Sekula D, Reczek P, Rusch V, Dawson MI, Dmitrovsky E. Cyclin D1 proteolysis: a retinoid chemoprevention signal in normal, immortalized, and transformed human bronchial epithelial cells. Journal of the National Cancer Institute. 91: 373-9. PMID 10050872 DOI: 10.1093/Jnci/91.4.373 |
0.479 |
|
| 1999 |
Yeyati PL, Shaknovich R, Boterashvili S, Li J, Ball HJ, Waxman S, Nason-Burchenal K, Dmitrovsky E, Zelent A, Licht JD. Leukemia translocation protein PLZF inhibits cell growth and expression of cyclin A. Oncogene. 18: 925-34. PMID 10023668 DOI: 10.1038/Sj.Onc.1202375 |
0.359 |
|
| 1998 |
Nason-Burchenal K, Takle G, Pace U, Flynn S, Allopenna J, Martin P, George ST, Goldberg AR, Dmitrovsky E. Targeting the PML/RAR alpha translocation product triggers apoptosis in promyelocytic leukemia cells. Oncogene. 17: 1759-68. PMID 9778041 DOI: 10.1038/Sj.Onc.1202075 |
0.362 |
|
| 1998 |
Maerz WJ, Baselga J, Reuter VE, Mellado B, Myers ML, Bosl GJ, Spinella MJ, Dmitrovsky E. FGF4 dissociates anti-tumorigenic from differentiation signals of retinoic acid in human embryonal carcinomas Oncogene. 17: 761-767. PMID 9715278 DOI: 10.1038/Sj.Onc.1201992 |
0.493 |
|
| 1998 |
Spinella MJ, Kitareewan S, Mellado B, Sekula D, Khoo KS, Dmitrovsky E. Specific retinoid receptors cooperate to signal growth suppression and maturation of human embryonal carcinoma cells. Oncogene. 16: 3471-80. PMID 9692555 DOI: 10.1038/Sj.Onc.1201876 |
0.425 |
|
| 1998 |
Nason-Burchenal K, Allopenna J, Bègue A, Stéhelin D, Dmitrovsky E, Martin P. Targeting of PML/RAR Is Lethal to Retinoic Acid–Resistant Promyelocytic Leukemia Cells Blood. 92: 1758-1767. DOI: 10.1182/Blood.V92.5.1758 |
0.427 |
|
| 1997 |
Albanell J, Lonardo F, Rusch V, Engelhardt M, Langenfeld J, Han W, Klimstra D, Venkatraman E, Moore MA, Dmitrovsky E. High telomerase activity in primary lung cancers: association with increased cell proliferation rates and advanced pathologic stage. Journal of the National Cancer Institute. 89: 1609-15. PMID 9362159 DOI: 10.1093/Jnci/89.21.1609 |
0.518 |
|
| 1997 |
Nason-Burchenal K, Maerz W, Albanell J, Allopenna J, Martin P, Moore MA, Dmitrovsky E. Common defects of different retinoic acid resistant promyelocytic leukemia cells are persistent telomerase activity and nuclear body disorganization. Differentiation; Research in Biological Diversity. 61: 321-31. PMID 9342843 DOI: 10.1046/J.1432-0436.1997.6150321.X |
0.355 |
|
| 1997 |
Langenfeld J, Kiyokawa H, Sekula D, Boyle J, Dmitrovsky E. Posttranslational regulation of cyclin D1 by retinoic acid: a chemoprevention mechanism. Proceedings of the National Academy of Sciences of the United States of America. 94: 12070-4. PMID 9342364 DOI: 10.1073/Pnas.94.22.12070 |
0.471 |
|
| 1996 |
Moasser MM, Khoo KS, Maerz WJ, Zelenetz A, Dmitrovsky E. Derivation and characterization of retinoid-resistant human embryonal carcinoma cells. Differentiation; Research in Biological Diversity. 60: 251-7. PMID 8765055 DOI: 10.1046/J.1432-0436.1996.6040251.X |
0.404 |
|
| 1996 |
Early E, Moore MA, Kakizuka A, Nason-Burchenal K, Martin P, Evans RM, Dmitrovsky E. Transgenic expression of PML/RARalpha impairs myelopoiesis. Proceedings of the National Academy of Sciences of the United States of America. 93: 7900-4. PMID 8755574 DOI: 10.1073/Pnas.93.15.7900 |
0.328 |
|
| 1996 |
Baldassarre G, Bianco C, Tortora G, Ruggiero A, Moasser M, Dmitrovsky E, Bianco AR, Ciardiello F. Transfection with a CRIPTO anti-sense plasmid suppresses endogenous CRIPTO expression and inhibits transformation in a human embryonal carcinoma cell line. International Journal of Cancer. 66: 538-43. PMID 8635871 DOI: 10.1002/(Sici)1097-0215(19960516)66:4<538::Aid-Ijc19>3.0.Co;2-3 |
0.447 |
|
| 1996 |
Nason-Burchenal K, Gandini D, Botto M, Allopenna J, Seale J, Cross N, Goldman J, Dmitrovsky E, Pandolfi P. Interferon augments PML and PML/RAR alpha expression in normal myeloid and acute promyelocytic cells and cooperates with all-trans retinoic acid to induce maturation of a retinoid-resistant promyelocytic cell line Blood. 88: 3926-3936. DOI: 10.1182/Blood.V88.10.3926.Bloodjournal88103926 |
0.417 |
|
| 1994 |
Kurie JM, Allopenna J, Dmitrovsky E. Retinoic acid stimulates protein kinase A-associated G proteins during human teratocarcinoma differentiation. Biochimica Et Biophysica Acta. 1222: 88-94. PMID 8186270 DOI: 10.1016/0167-4889(94)90028-0 |
0.426 |
|
| 1993 |
Kurie JM, Younes A, Miller WH, Burchert M, Chiu CF, Kolesnick R, Dmitrovsky E. Retinoic acid stimulates the protein kinase C pathway before activation of its beta-nuclear receptor during human teratocarcinoma differentiation. Biochimica Et Biophysica Acta. 1179: 203-7. PMID 8218362 DOI: 10.1016/0167-4889(93)90142-C |
0.406 |
|
| 1993 |
Miller WJ, Levine K, DeBlasio A, Frankel S, Dmitrovsky E, Warrell RJ. Detection of minimal residual disease in acute promyelocytic leukemia by a reverse transcription polymerase chain reaction assay for the PML/RAR-alpha fusion mRNA Blood. 82: 1689-1694. DOI: 10.1182/Blood.V82.6.1689.1689 |
0.301 |
|
| 1993 |
Kurie JM, Brown P, Salk E, Scheinberg D, Birrer M, Deutsch P, Dmitrovsky E. Cooperation between retinoic acid and phorbol esters enhances human teratocarcinoma differentiation Differentiation. 54: 115-122. DOI: 10.1111/J.1432-0436.1993.Tb01594.X |
0.317 |
|
| 1992 |
Dmitrovsky E, Bosl GJ. Active cancer therapy combining 13-cis-retinoic acid with interferon-alpha. Journal of the National Cancer Institute. 84: 218-9. PMID 1734081 DOI: 10.1093/Jnci/84.4.218 |
0.315 |
|
| 1992 |
Miller WH, Dmitrovsky E. Growth factors in human germ cell cancer. Recent Results in Cancer Research. Fortschritte Der Krebsforschung. Progres Dans Les Recherches Sur Le Cancer. 123: 183-9. PMID 1660620 DOI: 10.1007/978-3-642-84485-0_19 |
0.323 |
|
| 1992 |
Miller WH, Kakizuka A, Frankel SR, Warrell RP, DeBlasio A, Levine K, Evans RM, Dmitrovsky E. Reverse transcription polymerase chain reaction for the rearranged retinoic acid receptor alpha clarifies diagnosis and detects minimal residual disease in acute promyelocytic leukemia. Proceedings of the National Academy of Sciences of the United States of America. 89: 2694-8. PMID 1372989 DOI: 10.1073/Pnas.89.7.2694 |
0.31 |
|
| 1992 |
Rusch VW, Reuter VE, Kris MG, Kurie J, Miller WH, Nanus DM, Albino AP, Dmitrovsky E. Ras oncogene point mutation: an infrequent event in bronchioloalveolar cancer. The Journal of Thoracic and Cardiovascular Surgery. 104: 1465-1469. DOI: 10.1016/S0022-5223(19)34644-6 |
0.41 |
|
| 1991 |
Miller WH, Dmitrovsky E. Oncogenes and clinical oncology. Current Opinion in Oncology. 3: 65-9. PMID 1646034 DOI: 10.1097/00001622-199102000-00010 |
0.43 |
|
| 1990 |
Bosl GJ, Dmitrovsky E, Reuter VE, Samaniego F, Rodriguez E, Geller NL, Chaganti RS. Isochromosome of the short arm of chromosome 12: clinically useful markers for male germ cell tumors. Journal of the National Cancer Institute. 81: 1874-8. PMID 2556586 DOI: 10.1093/Jnci/81.24.1874 |
0.304 |
|
| 1990 |
Dmitrovsky E, Seifter EJ, Gazdar AF, Tsai CM, Edison M, Brantley P, Veach SR, Batist G, Ihde DC, Mulshine JL. A phase II trial of carboplatin (CBDCA) in small-cell and non-small-cell lung cancer with correlation to in vitro analysis of cytotoxicity. American Journal of Clinical Oncology. 13: 285-9. PMID 2165737 DOI: 10.1097/00000421-199008000-00003 |
0.344 |
|
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