Thomas Graeber - Publications

Affiliations: 
University of California, Los Angeles, Los Angeles, CA 
Area:
Biomedical Engineering, Molecular Biology

45 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Shia DW, Choi W, Vijayaraj P, Vuong V, Sandlin JM, Lu MM, Aziz A, Marin C, Aros CJ, Sen C, Durra A, Lund AJ, Purkayastha A, Rickabaugh TM, Graeber TG, et al. Targeting PEA3 transcription factors to mitigate small cell lung cancer progression. Oncogene. PMID 36509998 DOI: 10.1038/s41388-022-02558-6  0.338
2020 Court CM, Hou S, Liu L, Winograd P, DiPardo BJ, Liu SX, Chen PJ, Zhu Y, Smalley M, Zhang R, Sadeghi S, Finn RS, Kaldas FM, Busuttil RW, Zhou XJ, ... ... Graeber TG, et al. Somatic copy number profiling from hepatocellular carcinoma circulating tumor cells. Npj Precision Oncology. 4: 16. PMID 32637655 DOI: 10.1200/Jco.2018.36.4_Suppl.290  0.365
2020 Shia DW, Vuong V, Pecora E, Balanis N, Vijayaraj P, Sen C, Aros CJ, Rickabaugh T, Graeber T, Gomperts B. B06 Time-Resolved RNA-Seq Identifies Transient Gene Expression Changes Following Initial Chemotherapy Challenge in Small-Cell Lung Cancer Journal of Thoracic Oncology. 15. DOI: 10.1016/J.Jtho.2019.12.075  0.364
2019 Wang L, Smith BA, Balanis NG, Tsai BL, Nguyen K, Cheng MW, Obusan MB, Esedebe FN, Patel SJ, Zhang H, Clark PM, Sisk AE, Said JW, Huang J, Graeber TG, et al. A genetically defined disease model reveals that urothelial cells can initiate divergent bladder cancer phenotypes. Proceedings of the National Academy of Sciences of the United States of America. PMID 31871155 DOI: 10.1073/Pnas.1915770117  0.307
2019 Yao DW, Balanis NG, Eskin E, Graeber TG. A linear mixed model approach to gene expression-tumor aneuploidy association studies. Scientific Reports. 9: 11944. PMID 31420589 DOI: 10.1038/S41598-019-48302-1  0.303
2019 Balanis NG, Sheu KM, Esedebe FN, Patel SJ, Smith BA, Park JW, Alhani S, Gomperts BN, Huang J, Witte ON, Graeber TG. Pan-cancer Convergence to a Small-Cell Neuroendocrine Phenotype that Shares Susceptibilities with Hematological Malignancies. Cancer Cell. 36: 17-34.e7. PMID 31287989 DOI: 10.1016/J.Ccell.2019.06.005  0.369
2019 Olcina MM, Balanis NG, Kim RK, Thompson MJ, Graeber TG, Giaccia AJ. Abstract A097: Complement system mutations in cancer: Uncovering new relationships between tumor hypoxia and complement Cancer Immunology Research. 7. DOI: 10.1158/2326-6074.Cricimteatiaacr18-A097  0.31
2019 Graeber T. Abstract ES6-3: Systems approaches to attacking cancer vulnerabilities defined by metabolic, de-differentiation and genomic instability states Cancer Research. 79. DOI: 10.1158/1538-7445.Sabcs18-Es6-3  0.452
2019 Bayley N, Tse C, Baufeld L, Gosa L, Yan W, Zhu H, Balanis N, Cloughesy T, Liau L, Graeber T, Nathanson D. TMIC-26. PRECLINICAL MODEL SYSTEMS OF GLIOBLASTOMA REVEAL MICROENVIRONMENTAL PROGRAMS AND DEPENDENCIES IN PATIENT TUMORS Neuro-Oncology. 21: vi253-vi253. DOI: 10.1093/Neuonc/Noz175.1060  0.401
2018 Olcina MM, Balanis NG, Kim RK, Aksoy BA, Kodysh J, Thompson MJ, Hammerbacher J, Graeber TG, Giaccia AJ. Mutations in an Innate Immunity Pathway Are Associated with Poor Overall Survival Outcomes and Hypoxic Signaling in Cancer. Cell Reports. 25: 3721-3732.e6. PMID 30590044 DOI: 10.1016/J.Celrep.2018.11.093  0.335
2018 Park JW, Lee JK, Sheu KM, Wang L, Balanis NG, Nguyen K, Smith BA, Cheng C, Tsai BL, Cheng D, Huang J, Kurdistani SK, Graeber TG, Witte ON. Reprogramming normal human epithelial tissues to a common, lethal neuroendocrine cancer lineage. Science (New York, N.Y.). 362: 91-95. PMID 30287662 DOI: 10.1126/Science.Aat5749  0.344
2018 Xu S, Catapang A, Braas D, Stiles L, Doh HM, Lee JT, Graeber TG, Damoiseaux R, Shirihai O, Herschman HR. A precision therapeutic strategy for hexokinase 1-null, hexokinase 2-positive cancers. Cancer & Metabolism. 6: 7. PMID 29988332 DOI: 10.1186/S40170-018-0181-8  0.332
2018 Xu S, Catapang A, Doh HM, Bayley NA, Lee JT, Braas D, Graeber TG, Herschman HR. Hexokinase 2 is targetable for HK1 negative, HK2 positive tumors from a wide variety of tissues of origin. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 29880505 DOI: 10.2967/Jnumed.118.212365  0.345
2018 Lee JK, Bangayan NJ, Chai T, Smith BA, Pariva TE, Yun S, Vashisht A, Zhang Q, Park JW, Corey E, Huang J, Graeber TG, Wohlschlegel J, Witte ON. Systemic surfaceome profiling identifies target antigens for immune-based therapy in subtypes of advanced prostate cancer. Proceedings of the National Academy of Sciences of the United States of America. PMID 29686080 DOI: 10.1073/Pnas.1802354115  0.333
2018 Hu-Lieskovan S, Torrejon DY, Zaretsky JM, Tsoi J, Cheung-Lau G, Vega-Crespo A, Meeth K, Prins RM, Graeber T, Besenberg M, Grasso C, Comin-Anduix B, Ribas A. Role of CD4 cells in the complete anti-tumor response to PD1 blockade in a syngeneic murine melanoma model with activated WNT signaling. Journal of Clinical Oncology. 36: 12013-12013. DOI: 10.1200/Jco.2018.36.15_Suppl.12013  0.346
2018 Momcilovic M, Bailey ST, Lee JT, Magyar C, Braas D, Graeber T, Parlati F, Demo S, Krysan K, Walser TC, Dubinett SM, Sadeghi S, Christofk HR, Shackelford DB. Abstract B28: Targeted inhibition of EGFR and glutaminase induces metabolic crisis in EGFR-mutant lung cancer Clinical Cancer Research. 24. DOI: 10.1158/1557-3265.Aacriaslc18-B28  0.442
2017 Flores A, Schell J, Krall AS, Jelinek D, Miranda M, Grigorian M, Braas D, White AC, Zhou JL, Graham NA, Graeber T, Seth P, Evseenko D, Coller HA, Rutter J, et al. Lactate dehydrogenase activity drives hair follicle stem cell activation. Nature Cell Biology. PMID 28812580 DOI: 10.1038/Ncb3575  0.328
2017 Graham NA, Minasyan A, Lomova A, Cass A, Balanis NG, Friedman M, Chan S, Zhao S, Delgado A, Go J, Beck L, Hurtz C, Ng C, Qiao R, Ten Hoeve J, ... ... Graeber TG, et al. Recurrent patterns of DNA copy number alterations in tumors reflect metabolic selection pressures. Molecular Systems Biology. 13: 914. PMID 28202506 DOI: 10.15252/Msb.20167159  0.33
2017 Momcilovic M, Bailey ST, Lee JT, Fishbein MC, Magyar C, Braas D, Graeber T, Jackson NJ, Czernin J, Emberley E, Gross M, Janes J, Mackinnon A, Pan A, Rodriguez M, et al. Targeted Inhibition of EGFR and Glutaminase Induces Metabolic Crisis in EGFR Mutant Lung Cancer. Cell Reports. 18: 601-610. PMID 28099841 DOI: 10.1016/J.Celrep.2016.12.061  0.442
2017 Momcilovic M, Bailey ST, Lee JT, Braas D, Graeber TG, Works M, Parlati F, Demo S, Walser TC, Dubinett SM, Sadeghi S, Christofk H, Shackelford DB. Abstract 1830: Targeted inhibition of EGFR and glutaminase induces metabolic crisis in EGFR mutant lung cancer Cancer Research. 77: 1830-1830. DOI: 10.1158/1538-7445.Am2017-1830  0.341
2016 Drake JM, Paull EO, Graham NA, Lee JK, Smith BA, Titz B, Stoyanova T, Faltermeier CM, Uzunangelov V, Carlin DE, Fleming DT, Wong CK, Newton Y, Sudha S, Vashisht AA, ... ... Graeber TG, et al. Phosphoproteome Integration Reveals Patient-Specific Networks in Prostate Cancer. Cell. PMID 27499020 DOI: 10.1016/J.Cell.2016.07.007  0.4
2016 Sood A, Miller AM, Brogi E, Sui Y, Armenia J, McDonough E, Santamaria-Pang A, Carlin S, Stamper A, Campos C, Pang Z, Li Q, Port E, Graeber TG, Schultz N, et al. Multiplexed immunofluorescence delineates proteomic cancer cell states associated with metabolism. Jci Insight. 1. PMID 27182557 DOI: 10.1172/jci.insight.87030  0.332
2016 Hong CS, Graham NA, Gu W, Espindola Camacho C, Mah V, Maresh EL, Alavi M, Bagryanova L, Krotee PA, Gardner BK, Behbahan IS, Horvath S, Chia D, Mellinghoff IK, Hurvitz SA, ... ... Graeber TG, et al. MCT1 Modulates Cancer Cell Pyruvate Export and Growth of Tumors that Co-express MCT1 and MCT4. Cell Reports. PMID 26876179 DOI: 10.1016/J.Celrep.2016.01.057  0.358
2016 Su Y, Wei W, Xue M, Robert L, Tsoi J, Graeber T, Ribas A, Heath J. Abstract 879: Single cell analysis resolves combinatory targeted therapy for arresting the BRAFi-induced cellular dedifferentiation of metastatic melanomas Cancer Research. 76: 879-879. DOI: 10.1158/1538-7445.Am2016-879  0.4
2016 Drake JM, Paull EO, Graham NA, Lee JK, Smith BA, Stoyanova T, Faltermeier CM, Carlin DE, Vashisht A, Huang J, Wohlschlegel JA, Graeber TG, Witte ON, Stuart JM. Abstract 3882: Patient-specific druggable networks in lethal prostate cancer through proteome-guided multi-omic integration Cancer Research. 76: 3882-3882. DOI: 10.1158/1538-7445.Am2016-3882  0.379
2015 Ting PY, Johnson CW, Fang C, Cao X, Graeber TG, Mattos C, Colicelli J. Tyrosine phosphorylation of RAS by ABL allosterically enhances effector binding. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 25999467 DOI: 10.1096/Fj.15-271510  0.55
2015 Chan LN, Braas D, Hurtz C, Shojaee S, Geng H, Cazzaniga V, Ng C, Masouleh BK, Qiu YH, Zhang N, Coombes KR, Ernst T, Cazzaniga G, Hochhaus A, Kornblau S, ... Graeber T, et al. Abstract 1124: Transcriptional control of B cell identity restricts metabolic fitness in human leukemia Cancer Research. 75: 1124-1124. DOI: 10.1158/1538-7445.Am2015-1124  0.339
2014 Anderson JL, Titz B, Akiyama R, Komisopoulou E, Park A, Tap WD, Graeber TG, Denny CT. Phosphoproteomic profiling reveals IL6-mediated paracrine signaling within the Ewing sarcoma family of tumors. Molecular Cancer Research : McR. 12: 1740-54. PMID 25092916 DOI: 10.1158/1541-7786.Mcr-14-0159  0.313
2014 Atefi M, Avramis E, Lassen A, Wong DJ, Robert L, Foulad D, Cerniglia M, Titz B, Chodon T, Graeber TG, Comin-Anduix B, Ribas A. Effects of MAPK and PI3K pathways on PD-L1 expression in melanoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 3446-57. PMID 24812408 DOI: 10.1158/1078-0432.Ccr-13-2797  0.309
2014 Chan LN, Braas D, Hurtz C, Shojaee S, Kharabi Masouleh B, Geng H, Ernst T, Hochhaus A, Graeber T, Muschen M. Lineage-Specific Metabolic Reprogramming Reveals LKB1 as Therapeutic Target in Acute Lymphoblastic Leukemia Blood. 124: 783-783. DOI: 10.1182/Blood.V124.21.783.783  0.373
2014 Mok S, Koya R, Tsoi J, Robert L, Zaretsky J, Tsui C, Graeber T, Ribas A. Abstract 147: Improving antitumor effects of a BRAF inhibitor with a colony stimulating factor 1 receptor (CSF-1R) inhibitor, PLX3397 Cancer Research. 74: 147-147. DOI: 10.1158/1538-7445.Am2014-147  0.338
2013 Drake JM, Graham NA, Lee JK, Stoyanova T, Faltermeier CM, Sud S, Titz B, Huang J, Pienta KJ, Graeber TG, Witte ON. Metastatic castration-resistant prostate cancer reveals intrapatient similarity and interpatient heterogeneity of therapeutic kinase targets. Proceedings of the National Academy of Sciences of the United States of America. 110: E4762-9. PMID 24248375 DOI: 10.1073/Pnas.1319948110  0.334
2012 Tran LM, Chang CJ, Plaisier S, Wu S, Dang J, Mischel PS, Liao JC, Graeber TG, Wu H. Determining PTEN functional status by network component deduced transcription factor activities. Plos One. 7: e31053. PMID 22347425 DOI: 10.1371/Journal.Pone.0031053  0.732
2012 Drake JM, Graham NA, Stoyanova T, Sedghi A, Goldstein AS, Cai H, Smith DA, Zhang H, Komisopoulou E, Huang J, Graeber TG, Witte ON. Oncogene-specific activation of tyrosine kinase networks during prostate cancer progression. Proceedings of the National Academy of Sciences of the United States of America. 109: 1643-8. PMID 22307624 DOI: 10.1073/Pnas.1120985109  0.321
2012 Geng H, Nahar R, Ramezani-Rad P, Chen Z, Tyner JW, Chang BH, Titz B, Buchner M, Hurtz C, Graeber TG, Druker BJ, Paietta E, Melnick A, Willman CL, Carroll WL, et al. Integrative Analysis of Ikaros-Dependent Changes of Transcriptional Regulation and Tyrosine Phosphorylation Events in Ph+ ALL Blood. 120: 528-528. DOI: 10.1182/Blood.V120.21.528.528  0.331
2011 Zuber J, Rappaport AR, Luo W, Wang E, Chen C, Vaseva AV, Shi J, Weissmueller S, Fellmann C, Fellman C, Taylor MJ, Weissenboeck M, Graeber TG, Kogan SC, Vakoc CR, et al. An integrated approach to dissecting oncogene addiction implicates a Myb-coordinated self-renewal program as essential for leukemia maintenance. Genes & Development. 25: 1628-40. PMID 21828272 DOI: 10.1101/Gad.17269211  0.301
2011 Palaskas N, Larson SM, Schultz N, Komisopoulou E, Wong J, Rohle D, Campos C, Yannuzzi N, Osborne JR, Linkov I, Kastenhuber ER, Taschereau R, Plaisier SB, Tran C, Heguy A, ... ... Graeber TG, et al. 18F-fluorodeoxy-glucose positron emission tomography marks MYC-overexpressing human basal-like breast cancers. Cancer Research. 71: 5164-74. PMID 21646475 DOI: 10.1158/0008-5472.Can-10-4633  0.703
2011 Mulholland DJ, Tran LM, Li Y, Cai H, Morim A, Wang S, Plaisier S, Garraway IP, Huang J, Graeber TG, Wu H. Cell autonomous role of PTEN in regulating castration-resistant prostate cancer growth. Cancer Cell. 19: 792-804. PMID 21620777 DOI: 10.1016/J.Ccr.2011.05.006  0.714
2011 Nahar R, Ramezani-Rad P, Dovat S, Buchner M, Graeber TG, Muschen M. Mechanisms of Ikaros-Mediated Tumor Suppression Blood. 118: 408-408. DOI: 10.1182/Blood.V118.21.408.408  0.304
2011 Remacle F, Graeber TG, Levine RD. Whose Entropy: A Maximal Entropy Analysis of Phosphorylation Signaling Journal of Statistical Physics. 144: 429-442. DOI: 10.1007/S10955-011-0215-X  0.312
2010 Fang C, Wang Y, Vu NT, Lin WY, Hsieh YT, Rubbi L, Phelps ME, Müschen M, Kim YM, Chatziioannou AF, Tseng HR, Graeber TG. Integrated microfluidic and imaging platform for a kinase activity radioassay to analyze minute patient cancer samples. Cancer Research. 70: 8299-308. PMID 20837665 DOI: 10.1158/0008-5472.Can-10-0851  0.577
2010 Plaisier SB, Taschereau R, Wong JA, Graeber TG. Rank-rank hypergeometric overlap: identification of statistically significant overlap between gene-expression signatures. Nucleic Acids Research. 38: e169. PMID 20660011 DOI: 10.1093/Nar/Gkq636  0.703
2009 Lu KV, Zhu S, Cvrljevic A, Huang TT, Sarkaria S, Ahkavan D, Dang J, Dinca EB, Plaisier SB, Oderberg I, Lee Y, Chen Z, Caldwell JS, Xie Y, Loo JA, ... ... Graeber T, et al. Fyn and SRC are effectors of oncogenic epidermal growth factor receptor signaling in glioblastoma patients. Cancer Research. 69: 6889-98. PMID 19690143 DOI: 10.1158/0008-5472.Can-09-0347  0.699
2003 Ellwood-Yen K, Graeber TG, Wongvipat J, Iruela-Arispe ML, Zhang J, Matusik R, Thomas GV, Sawyers CL. Myc-driven murine prostate cancer shares molecular features with human prostate tumors. Cancer Cell. 4: 223-38. PMID 14522256 DOI: 10.1016/S1535-6108(03)00197-1  0.33
2003 Freedland SJ, Pantuck AJ, Paik SH, Zisman A, Graeber TG, Eisenberg D, McBride WH, Nguyen D, Tso CL, Belldegrun AS. Heterogeneity of molecular targets on clonal cancer lines derived from a novel hormone-refractory prostate cancer tumor system. The Prostate. 55: 299-307. PMID 12712409 DOI: 10.1002/Pros.10226  0.335
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