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Thomas G. Graeber - Publications

Affiliations: 
University of California, Los Angeles, Los Angeles, CA 
Area:
Biomedical Engineering, Molecular Biology
Website:
https://www.pharmacology.ucla.edu/people/thomas-graeber-ph-d/
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47/200 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Chen CC, Tran W, Song K, Sugimoto T, Obusan MB, Wang L, Sheu KM, Cheng D, Ta L, Varuzhanyan G, Huang A, Xu R, Zeng Y, Borujerdpur A, Bayley NA, ... ... Graeber TG, et al. Temporal evolution reveals bifurcated lineages in aggressive neuroendocrine small cell prostate cancer trans-differentiation. Cancer Cell. PMID 37995683 DOI: 10.1016/j.ccell.2023.10.009  0.308
2022 Shia DW, Choi W, Vijayaraj P, Vuong V, Sandlin JM, Lu MM, Aziz A, Marin C, Aros CJ, Sen C, Durra A, Lund AJ, Purkayastha A, Rickabaugh TM, Graeber TG, et al. Targeting PEA3 transcription factors to mitigate small cell lung cancer progression. Oncogene. PMID 36509998 DOI: 10.1038/s41388-022-02558-6  0.316
2020 Olcina MM, Kim RK, Balanis NG, Li CG, von Eyben R, Graeber TG, Ricklin D, Stucki M, Giaccia AJ. Intracellular C4BPA Levels Regulate NF-κB-Dependent Apoptosis. Iscience. 23: 101594. PMID 33205012 DOI: 10.1016/j.isci.2020.101594  0.515
2020 Court CM, Hou S, Liu L, Winograd P, DiPardo BJ, Liu SX, Chen PJ, Zhu Y, Smalley M, Zhang R, Sadeghi S, Finn RS, Kaldas FM, Busuttil RW, Zhou XJ, ... ... Graeber TG, et al. Somatic copy number profiling from hepatocellular carcinoma circulating tumor cells. Npj Precision Oncology. 4: 16. PMID 32637655 DOI: 10.1200/Jco.2018.36.4_Suppl.290  0.361
2020 Shia DW, Vuong V, Pecora E, Balanis N, Vijayaraj P, Sen C, Aros CJ, Rickabaugh T, Graeber T, Gomperts B. B06 Time-Resolved RNA-Seq Identifies Transient Gene Expression Changes Following Initial Chemotherapy Challenge in Small-Cell Lung Cancer Journal of Thoracic Oncology. 15. DOI: 10.1016/J.Jtho.2019.12.075  0.351
2019 Wang L, Smith BA, Balanis NG, Tsai BL, Nguyen K, Cheng MW, Obusan MB, Esedebe FN, Patel SJ, Zhang H, Clark PM, Sisk AE, Said JW, Huang J, Graeber TG, et al. A genetically defined disease model reveals that urothelial cells can initiate divergent bladder cancer phenotypes. Proceedings of the National Academy of Sciences of the United States of America. PMID 31871155 DOI: 10.1073/Pnas.1915770117  0.302
2019 Balanis NG, Sheu KM, Esedebe FN, Patel SJ, Smith BA, Park JW, Alhani S, Gomperts BN, Huang J, Witte ON, Graeber TG. Pan-cancer Convergence to a Small-Cell Neuroendocrine Phenotype that Shares Susceptibilities with Hematological Malignancies. Cancer Cell. 36: 17-34.e7. PMID 31287989 DOI: 10.1016/J.Ccell.2019.06.005  0.354
2019 Olcina MM, Balanis NG, Kim RK, Thompson MJ, Graeber TG, Giaccia AJ. Abstract A097: Complement system mutations in cancer: Uncovering new relationships between tumor hypoxia and complement Cancer Immunology Research. 7. DOI: 10.1158/2326-6074.Cricimteatiaacr18-A097  0.527
2019 Graeber T. Abstract ES6-3: Systems approaches to attacking cancer vulnerabilities defined by metabolic, de-differentiation and genomic instability states Cancer Research. 79. DOI: 10.1158/1538-7445.Sabcs18-Es6-3  0.44
2019 Bayley N, Tse C, Baufeld L, Gosa L, Yan W, Zhu H, Balanis N, Cloughesy T, Liau L, Graeber T, Nathanson D. TMIC-26. PRECLINICAL MODEL SYSTEMS OF GLIOBLASTOMA REVEAL MICROENVIRONMENTAL PROGRAMS AND DEPENDENCIES IN PATIENT TUMORS Neuro-Oncology. 21: vi253-vi253. DOI: 10.1093/Neuonc/Noz175.1060  0.39
2018 Olcina MM, Balanis NG, Kim RK, Aksoy BA, Kodysh J, Thompson MJ, Hammerbacher J, Graeber TG, Giaccia AJ. Mutations in an Innate Immunity Pathway Are Associated with Poor Overall Survival Outcomes and Hypoxic Signaling in Cancer. Cell Reports. 25: 3721-3732.e6. PMID 30590044 DOI: 10.1016/J.Celrep.2018.11.093  0.541
2018 Park JW, Lee JK, Sheu KM, Wang L, Balanis NG, Nguyen K, Smith BA, Cheng C, Tsai BL, Cheng D, Huang J, Kurdistani SK, Graeber TG, Witte ON. Reprogramming normal human epithelial tissues to a common, lethal neuroendocrine cancer lineage. Science (New York, N.Y.). 362: 91-95. PMID 30287662 DOI: 10.1126/Science.Aat5749  0.325
2018 Xu S, Catapang A, Braas D, Stiles L, Doh HM, Lee JT, Graeber TG, Damoiseaux R, Shirihai O, Herschman HR. A precision therapeutic strategy for hexokinase 1-null, hexokinase 2-positive cancers. Cancer & Metabolism. 6: 7. PMID 29988332 DOI: 10.1186/S40170-018-0181-8  0.312
2018 Xu S, Catapang A, Doh HM, Bayley NA, Lee JT, Braas D, Graeber TG, Herschman HR. Hexokinase 2 is targetable for HK1 negative, HK2 positive tumors from a wide variety of tissues of origin. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 29880505 DOI: 10.2967/Jnumed.118.212365  0.326
2018 Lee JK, Bangayan NJ, Chai T, Smith BA, Pariva TE, Yun S, Vashisht A, Zhang Q, Park JW, Corey E, Huang J, Graeber TG, Wohlschlegel J, Witte ON. Systemic surfaceome profiling identifies target antigens for immune-based therapy in subtypes of advanced prostate cancer. Proceedings of the National Academy of Sciences of the United States of America. PMID 29686080 DOI: 10.1073/Pnas.1802354115  0.312
2018 Hu-Lieskovan S, Torrejon DY, Zaretsky JM, Tsoi J, Cheung-Lau G, Vega-Crespo A, Meeth K, Prins RM, Graeber T, Besenberg M, Grasso C, Comin-Anduix B, Ribas A. Role of CD4 cells in the complete anti-tumor response to PD1 blockade in a syngeneic murine melanoma model with activated WNT signaling. Journal of Clinical Oncology. 36: 12013-12013. DOI: 10.1200/Jco.2018.36.15_Suppl.12013  0.34
2018 Momcilovic M, Bailey ST, Lee JT, Magyar C, Braas D, Graeber T, Parlati F, Demo S, Krysan K, Walser TC, Dubinett SM, Sadeghi S, Christofk HR, Shackelford DB. Abstract B28: Targeted inhibition of EGFR and glutaminase induces metabolic crisis in EGFR-mutant lung cancer Clinical Cancer Research. 24. DOI: 10.1158/1557-3265.Aacriaslc18-B28  0.426
2018 Olcina MM, Balanis NG, Kim RK, Thompson MJ, Graeber TG, Giaccia AJ. Abstract 4382: Complement system mutational landscape reveals C4BPA mutations enhance apoptosis in an immune-independent manner Cancer Research. 78: 4382-4382. DOI: 10.1158/1538-7445.Am2018-4382  0.499
2017 Flores A, Schell J, Krall AS, Jelinek D, Miranda M, Grigorian M, Braas D, White AC, Zhou JL, Graham NA, Graeber T, Seth P, Evseenko D, Coller HA, Rutter J, et al. Lactate dehydrogenase activity drives hair follicle stem cell activation. Nature Cell Biology. PMID 28812580 DOI: 10.1038/Ncb3575  0.322
2017 Graham NA, Minasyan A, Lomova A, Cass A, Balanis NG, Friedman M, Chan S, Zhao S, Delgado A, Go J, Beck L, Hurtz C, Ng C, Qiao R, Ten Hoeve J, ... ... Graeber TG, et al. Recurrent patterns of DNA copy number alterations in tumors reflect metabolic selection pressures. Molecular Systems Biology. 13: 914. PMID 28202506 DOI: 10.15252/Msb.20167159  0.32
2017 Momcilovic M, Bailey ST, Lee JT, Fishbein MC, Magyar C, Braas D, Graeber T, Jackson NJ, Czernin J, Emberley E, Gross M, Janes J, Mackinnon A, Pan A, Rodriguez M, et al. Targeted Inhibition of EGFR and Glutaminase Induces Metabolic Crisis in EGFR Mutant Lung Cancer. Cell Reports. 18: 601-610. PMID 28099841 DOI: 10.1016/J.Celrep.2016.12.061  0.424
2017 Momcilovic M, Bailey ST, Lee JT, Braas D, Graeber TG, Works M, Parlati F, Demo S, Walser TC, Dubinett SM, Sadeghi S, Christofk H, Shackelford DB. Abstract 1830: Targeted inhibition of EGFR and glutaminase induces metabolic crisis in EGFR mutant lung cancer Cancer Research. 77: 1830-1830. DOI: 10.1158/1538-7445.Am2017-1830  0.323
2016 Drake JM, Paull EO, Graham NA, Lee JK, Smith BA, Titz B, Stoyanova T, Faltermeier CM, Uzunangelov V, Carlin DE, Fleming DT, Wong CK, Newton Y, Sudha S, Vashisht AA, ... ... Graeber TG, et al. Phosphoproteome Integration Reveals Patient-Specific Networks in Prostate Cancer. Cell. PMID 27499020 DOI: 10.1016/J.Cell.2016.07.007  0.37
2016 Sood A, Miller AM, Brogi E, Sui Y, Armenia J, McDonough E, Santamaria-Pang A, Carlin S, Stamper A, Campos C, Pang Z, Li Q, Port E, Graeber TG, Schultz N, et al. Multiplexed immunofluorescence delineates proteomic cancer cell states associated with metabolism. Jci Insight. 1. PMID 27182557 DOI: 10.1172/jci.insight.87030  0.317
2016 Hong CS, Graham NA, Gu W, Espindola Camacho C, Mah V, Maresh EL, Alavi M, Bagryanova L, Krotee PA, Gardner BK, Behbahan IS, Horvath S, Chia D, Mellinghoff IK, Hurvitz SA, ... ... Graeber TG, et al. MCT1 Modulates Cancer Cell Pyruvate Export and Growth of Tumors that Co-express MCT1 and MCT4. Cell Reports. PMID 26876179 DOI: 10.1016/J.Celrep.2016.01.057  0.336
2016 Su Y, Wei W, Xue M, Robert L, Tsoi J, Graeber T, Ribas A, Heath J. Abstract 879: Single cell analysis resolves combinatory targeted therapy for arresting the BRAFi-induced cellular dedifferentiation of metastatic melanomas Cancer Research. 76: 879-879. DOI: 10.1158/1538-7445.Am2016-879  0.394
2016 Drake JM, Paull EO, Graham NA, Lee JK, Smith BA, Stoyanova T, Faltermeier CM, Carlin DE, Vashisht A, Huang J, Wohlschlegel JA, Graeber TG, Witte ON, Stuart JM. Abstract 3882: Patient-specific druggable networks in lethal prostate cancer through proteome-guided multi-omic integration Cancer Research. 76: 3882-3882. DOI: 10.1158/1538-7445.Am2016-3882  0.353
2015 Ting PY, Johnson CW, Fang C, Cao X, Graeber TG, Mattos C, Colicelli J. Tyrosine phosphorylation of RAS by ABL allosterically enhances effector binding. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 25999467 DOI: 10.1096/Fj.15-271510  0.539
2015 Chan LN, Braas D, Hurtz C, Shojaee S, Geng H, Cazzaniga V, Ng C, Masouleh BK, Qiu YH, Zhang N, Coombes KR, Ernst T, Cazzaniga G, Hochhaus A, Kornblau S, ... Graeber T, et al. Abstract 1124: Transcriptional control of B cell identity restricts metabolic fitness in human leukemia Cancer Research. 75: 1124-1124. DOI: 10.1158/1538-7445.Am2015-1124  0.338
2014 Atefi M, Avramis E, Lassen A, Wong DJ, Robert L, Foulad D, Cerniglia M, Titz B, Chodon T, Graeber TG, Comin-Anduix B, Ribas A. Effects of MAPK and PI3K pathways on PD-L1 expression in melanoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 3446-57. PMID 24812408 DOI: 10.1158/1078-0432.Ccr-13-2797  0.305
2014 Chan LN, Braas D, Hurtz C, Shojaee S, Kharabi Masouleh B, Geng H, Ernst T, Hochhaus A, Graeber T, Muschen M. Lineage-Specific Metabolic Reprogramming Reveals LKB1 as Therapeutic Target in Acute Lymphoblastic Leukemia Blood. 124: 783-783. DOI: 10.1182/Blood.V124.21.783.783  0.367
2014 Mok S, Koya R, Tsoi J, Robert L, Zaretsky J, Tsui C, Graeber T, Ribas A. Abstract 147: Improving antitumor effects of a BRAF inhibitor with a colony stimulating factor 1 receptor (CSF-1R) inhibitor, PLX3397 Cancer Research. 74: 147-147. DOI: 10.1158/1538-7445.Am2014-147  0.336
2013 Drake JM, Graham NA, Lee JK, Stoyanova T, Faltermeier CM, Sud S, Titz B, Huang J, Pienta KJ, Graeber TG, Witte ON. Metastatic castration-resistant prostate cancer reveals intrapatient similarity and interpatient heterogeneity of therapeutic kinase targets. Proceedings of the National Academy of Sciences of the United States of America. 110: E4762-9. PMID 24248375 DOI: 10.1073/Pnas.1319948110  0.302
2012 Tran LM, Chang CJ, Plaisier S, Wu S, Dang J, Mischel PS, Liao JC, Graeber TG, Wu H. Determining PTEN functional status by network component deduced transcription factor activities. Plos One. 7: e31053. PMID 22347425 DOI: 10.1371/Journal.Pone.0031053  0.746
2012 Geng H, Nahar R, Ramezani-Rad P, Chen Z, Tyner JW, Chang BH, Titz B, Buchner M, Hurtz C, Graeber TG, Druker BJ, Paietta E, Melnick A, Willman CL, Carroll WL, et al. Integrative Analysis of Ikaros-Dependent Changes of Transcriptional Regulation and Tyrosine Phosphorylation Events in Ph+ ALL Blood. 120: 528-528. DOI: 10.1182/Blood.V120.21.528.528  0.311
2011 Palaskas N, Larson SM, Schultz N, Komisopoulou E, Wong J, Rohle D, Campos C, Yannuzzi N, Osborne JR, Linkov I, Kastenhuber ER, Taschereau R, Plaisier SB, Tran C, Heguy A, ... ... Graeber TG, et al. 18F-fluorodeoxy-glucose positron emission tomography marks MYC-overexpressing human basal-like breast cancers. Cancer Research. 71: 5164-74. PMID 21646475 DOI: 10.1158/0008-5472.Can-10-4633  0.719
2011 Mulholland DJ, Tran LM, Li Y, Cai H, Morim A, Wang S, Plaisier S, Garraway IP, Huang J, Graeber TG, Wu H. Cell autonomous role of PTEN in regulating castration-resistant prostate cancer growth. Cancer Cell. 19: 792-804. PMID 21620777 DOI: 10.1016/J.Ccr.2011.05.006  0.729
2010 Fang C, Wang Y, Vu NT, Lin WY, Hsieh YT, Rubbi L, Phelps ME, Müschen M, Kim YM, Chatziioannou AF, Tseng HR, Graeber TG. Integrated microfluidic and imaging platform for a kinase activity radioassay to analyze minute patient cancer samples. Cancer Research. 70: 8299-308. PMID 20837665 DOI: 10.1158/0008-5472.Can-10-0851  0.56
2010 Plaisier SB, Taschereau R, Wong JA, Graeber TG. Rank-rank hypergeometric overlap: identification of statistically significant overlap between gene-expression signatures. Nucleic Acids Research. 38: e169. PMID 20660011 DOI: 10.1093/Nar/Gkq636  0.716
2009 Lu KV, Zhu S, Cvrljevic A, Huang TT, Sarkaria S, Ahkavan D, Dang J, Dinca EB, Plaisier SB, Oderberg I, Lee Y, Chen Z, Caldwell JS, Xie Y, Loo JA, ... ... Graeber T, et al. Fyn and SRC are effectors of oncogenic epidermal growth factor receptor signaling in glioblastoma patients. Cancer Research. 69: 6889-98. PMID 19690143 DOI: 10.1158/0008-5472.Can-09-0347  0.716
2003 Ellwood-Yen K, Graeber TG, Wongvipat J, Iruela-Arispe ML, Zhang J, Matusik R, Thomas GV, Sawyers CL. Myc-driven murine prostate cancer shares molecular features with human prostate tumors. Cancer Cell. 4: 223-38. PMID 14522256 DOI: 10.1016/S1535-6108(03)00197-1  0.305
2003 Freedland SJ, Pantuck AJ, Paik SH, Zisman A, Graeber TG, Eisenberg D, McBride WH, Nguyen D, Tso CL, Belldegrun AS. Heterogeneity of molecular targets on clonal cancer lines derived from a novel hormone-refractory prostate cancer tumor system. The Prostate. 55: 299-307. PMID 12712409 DOI: 10.1002/Pros.10226  0.309
1997 Kim CY, Tsai MH, Osmanian C, Calkins DP, Graeber TG, Greenspan DL, Kennedy AS, Rinker LH, Varia MA, DiPaolo JA, Peehl DM, Raleigh JA, Giaccia AJ. 142 The role of hypoxia, p53, and apoptosis in human cervical carcinoma pathogenesis International Journal of Radiation Oncology*Biology*Physics. 39: 206. DOI: 10.1016/S0360-3016(97)80701-8  0.376
1996 Graeber TG, Osmanian C, Jacks T, Housman DE, Koch CJ, Lowe SW, Giaccia AJ. Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours. Nature. 379: 88-91. PMID 8538748 DOI: 10.1038/379088A0  0.447
1996 Kim CY, Tsai M, Graeber TG, Peehl DM, Giaccia AJ. 2210 HPV E6 and E7 in hypoxia mediated tumorigenesis in cervical epithelial cells International Journal of Radiation Oncology*Biology*Physics. 36: 379. DOI: 10.1016/S0360-3016(97)85781-1  0.355
1994 Graeber TG, Peterson JF, Tsai M, Monica K, Fornace AJ, Giaccia AJ. Hypoxia induces accumulation of p53 protein, but activation of a G1-phase checkpoint by low-oxygen conditions is independent of p53 status. Molecular and Cellular Biology. 14: 6264-77. PMID 8065358 DOI: 10.1128/mcb.14.9.6264-6277.1994  0.428
1994 Graeber TG, Monica KA, Fornace AJ, Giaccia AJ. Low oxygen conditions activate a G1/S-phase checkpoint independent of p53 status International Journal of Radiation Oncology*Biology*Physics. 30: 196. DOI: 10.1016/0360-3016(94)90701-3  0.37
Low-probability matches (unlikely to be authored by this person)
2014 Anderson JL, Titz B, Akiyama R, Komisopoulou E, Park A, Tap WD, Graeber TG, Denny CT. Phosphoproteomic profiling reveals IL6-mediated paracrine signaling within the Ewing sarcoma family of tumors. Molecular Cancer Research : McR. 12: 1740-54. PMID 25092916 DOI: 10.1158/1541-7786.Mcr-14-0159  0.3
2011 Remacle F, Graeber TG, Levine RD. Whose Entropy: A Maximal Entropy Analysis of Phosphorylation Signaling Journal of Statistical Physics. 144: 429-442. DOI: 10.1007/S10955-011-0215-X  0.299
2011 Nahar R, Ramezani-Rad P, Dovat S, Buchner M, Graeber TG, Muschen M. Mechanisms of Ikaros-Mediated Tumor Suppression Blood. 118: 408-408. DOI: 10.1182/Blood.V118.21.408.408  0.297
2012 Drake JM, Graham NA, Stoyanova T, Sedghi A, Goldstein AS, Cai H, Smith DA, Zhang H, Komisopoulou E, Huang J, Graeber TG, Witte ON. Oncogene-specific activation of tyrosine kinase networks during prostate cancer progression. Proceedings of the National Academy of Sciences of the United States of America. 109: 1643-8. PMID 22307624 DOI: 10.1073/Pnas.1120985109  0.293
2011 Zuber J, Rappaport AR, Luo W, Wang E, Chen C, Vaseva AV, Shi J, Weissmueller S, Fellmann C, Fellman C, Taylor MJ, Weissenboeck M, Graeber TG, Kogan SC, Vakoc CR, et al. An integrated approach to dissecting oncogene addiction implicates a Myb-coordinated self-renewal program as essential for leukemia maintenance. Genes & Development. 25: 1628-40. PMID 21828272 DOI: 10.1101/Gad.17269211  0.29
2020 Flores YN, Sanchez GJ, Hoeve Jt, Amoon AT, Graeber T, Glenn BA, May FP, Durazo F, Zhang Z, Salmerón J, Pollock BH, Bastani R. Abstract 3122: Metabolic dysregulation and risk of non-alcoholic fatty liver disease in Mexican adults Clinical Trials. 80: 3122-3122. DOI: 10.1158/1538-7445.Am2020-3122  0.289
2013 Rohle D, Popovici-Muller J, Palaskas N, Turcan S, Grommes C, Campos C, Tsoi J, Clark O, Oldrini B, Komisopoulou E, Kunii K, Pedraza A, Schalm S, Silverman L, Miller A, ... ... Graeber TG, et al. An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells. Science (New York, N.Y.). 340: 626-30. PMID 23558169 DOI: 10.1126/Science.1236062  0.286
2023 Crane JN, Graham DS, Mona CE, Nelson SD, Samiei A, Dawson DW, Dry SM, Masri MG, Crompton JG, Benz MR, Czernin J, Eilber FC, Graeber TG, Calais J, Federman NC. Fibroblast Activation Protein Expression in Sarcomas. Sarcoma. 2023: 2480493. PMID 37333052 DOI: 10.1155/2023/2480493  0.285
2018 Graham N, Minasyan A, Christofk H, Mellinghoff I, Graeber TG. Abstract A113: Recurrent patterns of DNA copy number alterations in tumors reflect metabolic selection pressures Molecular Cancer Therapeutics. 17. DOI: 10.1158/1535-7163.Targ-17-A113  0.282
2019 Yao DW, Balanis NG, Eskin E, Graeber TG. A linear mixed model approach to gene expression-tumor aneuploidy association studies. Scientific Reports. 9: 11944. PMID 31420589 DOI: 10.1038/S41598-019-48302-1  0.282
2010 Sun J, Masterman-Smith MD, Graham NA, Jiao J, Mottahedeh J, Laks DR, Ohashi M, DeJesus J, Kamei K, Lee KB, Wang H, Yu ZT, Lu YT, Hou S, Li K, ... ... Graeber TG, et al. A microfluidic platform for systems pathology: multiparameter single-cell signaling measurements of clinical brain tumor specimens. Cancer Research. 70: 6128-38. PMID 20631065 DOI: 10.1158/0008-5472.Can-10-0076  0.278
2022 Bennett NK, Nakaoka HJ, Laurent D, Okimoto RA, Sei Y, Horvai AE, Bivona TG, Ten Hoeve J, Graeber TG, Nakamura K, Nakamura JL. Primary and metastatic tumors exhibit systems-level differences in dependence on mitochondrial respiratory function. Plos Biology. 20: e3001753. PMID 36137002 DOI: 10.1371/journal.pbio.3001753  0.277
2012 Koya RC, Mok S, Otte N, Blacketor KJ, Comin-Anduix B, Tumeh PC, Minasyan A, Graham NA, Graeber TG, Chodon T, Ribas A. BRAF inhibitor vemurafenib improves the antitumor activity of adoptive cell immunotherapy. Cancer Research. 72: 3928-37. PMID 22693252 DOI: 10.1158/0008-5472.CAN-11-2837  0.276
2012 Poulikakos PI, Persaud Y, Janakiraman M, Kong X, Ng C, Moriceau G, Shi H, Atefi M, Titz B, Gabay MT, Salton M, Dahlman KB, Tadi M, Wargo JA, Flaherty KT, ... ... Graeber TG, et al. Abstract LB-428: RAS-independent dimerization of BRAF(V600E) splicing variants promotes resistance to RAF inhibitors Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-428  0.276
2015 Atefi M, Titz B, Avramis E, Ng C, Wong DJ, Lassen A, Cerniglia M, Escuin-Ordinas H, Foulad D, Comin-Anduix B, Graeber TG, Ribas A. Combination of pan-RAF and MEK inhibitors in NRAS mutant melanoma. Molecular Cancer. 14: 27. PMID 25645078 DOI: 10.1186/S12943-015-0293-5  0.276
2016 Shojaee S, Chan LN, Buchner M, Cazzaniga V, Cosgun KN, Geng H, Qiu YH, von Minden MD, Ernst T, Hochhaus A, Cazzaniga G, Melnick A, Kornblau SM, Graeber TG, Wu H, et al. PTEN opposes negative selection and enables oncogenic transformation of pre-B cells. Nature Medicine. PMID 26974310 DOI: 10.1038/Nm.4062  0.276
2015 Hu-Lieskovan S, Mok S, Homet Moreno B, Tsoi J, Robert L, Goedert L, Pinheiro EM, Koya RC, Graeber TG, Comin-Anduix B, Ribas A. Improved antitumor activity of immunotherapy with BRAF and MEK inhibitors in BRAF(V600E) melanoma. Science Translational Medicine. 7: 279ra41. PMID 25787767 DOI: 10.1126/scitranslmed.aaa4691  0.275
2011 Rubbi L, Titz B, Brown L, Glavan E, Komisopoulou E, Chen SS, Low T, Tahmasian M, Skaggs B, Müschen M, Pellegrini M, Graeber TG. Abstract LB-25: Global phosphoproteomics reveals crosstalk between Bcr-Abl and negative feedback mechanisms controlling Src signaling Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Lb-25  0.274
2014 Shojaee S, Cazzaniga V, Schjerven H, Buchner M, Hurtz C, Geng H, Hochhaus A, Cazzaniga G, Melnick AM, Kornblau SM, Graeber TG, Muschen M. PTEN Is Essential for Normal Cytokine Signaling and Oncogenic Transformation of Pre-B Cells Blood. 124: 262-262. DOI: 10.1182/Blood.V124.21.262.262  0.269
2021 Minami J, Bayley N, Tse C, Zhu H, Morrow D, Yong W, Liau L, Cloughesy TF, Graeber T, Nathanson DA. ETMM-02. PRECLINICAL MODELS REVEAL BRAIN-MICROENVIRONMENT SPECIFIC METABOLIC DEPENDENCIES IN GLIOBLASTOMA Neuro-Oncology Advances. 3: i14-i14. DOI: 10.1093/noajnl/vdab024.058  0.269
2013 Knight DA, Ngiow SF, Li M, Parmenter T, Mok S, Cass A, Haynes NM, Kinross K, Yagita H, Koya RC, Graeber TG, Ribas A, McArthur GA, Smyth MJ. Host immunity contributes to the anti-melanoma activity of BRAF inhibitors. The Journal of Clinical Investigation. 123: 1371-81. PMID 23454771 DOI: 10.1172/JCI66236  0.268
2017 Su Y, Wei W, Robert L, Tsoi J, Xue M, Kim J, Graeber T, Levine R, Ribas A, Heath J. Abstract 2069: Overcoming drug resistance by targeting melanoma dedifferentiation through information-theoretic analysis and single cell proteomics Cancer Research. 77: 2069-2069. DOI: 10.1158/1538-7445.Am2017-2069  0.268
2012 Drake JM, Huang J, Graeber TG, Witte ON, Graham NA, Stoyanova T, Sedghi A, Goldstein AS, Cai H, Smith DA, Zhang H, Evangelia K. Abstract PR5: Therapeutic targeting of oncogene-specific tyrosine kinase networks during prostate cancer progression Cancer Research. 72: PR5-PR5. DOI: 10.1158/1538-7445.PRCA2012-PR5  0.268
2015 Ploper D, Taelman VF, Robert L, Perez BS, Titz B, Chen HW, Graeber TG, von Euw E, Ribas A, De Robertis EM. MITF drives endolysosomal biogenesis and potentiates Wnt signaling in melanoma cells. Proceedings of the National Academy of Sciences of the United States of America. 112: E420-9. PMID 25605940 DOI: 10.1073/pnas.1424576112  0.266
2020 Minami J, Bayley N, Tse C, Zhu H, Morrow D, Yong W, Liau L, Cloughesy T, Graeber T, Nathanson D. TAMI-06. PRECLINICAL MODELS REVEAL BRAIN-MICROENVIRONMENT SPECIFIC METABOLIC DEPENDENCIES IN GLIOBLASTOMA Neuro-Oncology. 22: ii214-ii214. DOI: 10.1093/neuonc/noaa215.895  0.265
2016 Li W, Cohen A, Sun Y, Squires J, Braas D, Graeber TG, Du L, Li G, Li Z, Xu X, Chen X, Huang J. The Role of CD44 in Glucose Metabolism in Prostatic Small Cell Neuroendocrine Carcinoma. Molecular Cancer Research : McR. PMID 26832214 DOI: 10.1158/1541-7786.MCR-15-0466  0.265
2018 Tsoi J, Robert L, Paraiso K, Galvan C, Sheu KM, Lay J, Wong DJL, Atefi M, Shirazi R, Wang X, Braas D, Grasso CS, Palaskas N, Ribas A, Graeber TG. Multi-stage Differentiation Defines Melanoma Subtypes with Differential Vulnerability to Drug-Induced Iron-Dependent Oxidative Stress. Cancer Cell. PMID 29657129 DOI: 10.1016/J.Ccell.2018.03.017  0.264
2017 Grommes C, Pastore A, Palaskas N, Tang SS, Campos C, Schartz D, Codega P, Nichol D, Clark O, Hsieh WY, Rohle D, Rosenblum MK, Viale A, Tabar V, Brennan CW, ... ... Graeber TG, et al. Ibrutinib Unmasks Critical Role of Bruton Tyrosine Kinase in Primary CNS Lymphoma. Cancer Discovery. PMID 28619981 DOI: 10.1158/2159-8290.Cd-17-0613  0.263
2021 Minami J, Bayley N, Tse C, Morrow D, Zhu H, Yong W, Liau L, Cloughesy T, Graeber T, Nathanson D. TAMI-26. INVESTIGATING TUMOR MICROENVIRONMENT METABOLIC DEPENDENCIES IN GLIOBLASTOMA Neuro-Oncology. 23: vi203-vi203. DOI: 10.1093/neuonc/noab196.810  0.262
2015 Robert L, Tsoi J, Diaz AG, Moreno BH, Truong N, Graeber T, Ribas A. Abstract 2682: Melanoma phenotype switching to adapt to BRAF inhibition Cancer Research. 75: 2682-2682. DOI: 10.1158/1538-7445.Am2015-2682  0.261
2012 Graham NA, Tahmasian M, Kohli B, Komisopoulou E, Zhu M, Vivanco I, Teitell MA, Wu H, Ribas A, Lo RS, Mellinghoff IK, Mischel PS, Graeber TG. Glucose deprivation activates a metabolic and signaling amplification loop leading to cell death. Molecular Systems Biology. 8: 589. PMID 22735335 DOI: 10.1038/Msb.2012.20  0.26
2001 Graeber TG, Eisenberg D. Bioinformatic identification of potential autocrine signaling loops in cancers from gene expression profiles. Nature Genetics. 29: 295-300. PMID 11685206 DOI: 10.1038/Ng755  0.259
2023 Hu J, Tan P, Ishihara M, Bayley NA, Schokrpur S, Reynoso JG, Zhang Y, Lim RJ, Dumitras C, Yang L, Dubinett SM, Jat PS, Van Snick J, Huang J, Chin AI, ... ... Graeber TG, et al. Tumor heterogeneity in VHL drives metastasis in clear cell renal cell carcinoma. Signal Transduction and Targeted Therapy. 8: 155. PMID 37069149 DOI: 10.1038/s41392-023-01362-2  0.257
2016 Atefi M, Titz B, Tsoi J, Avramis E, Le A, Ng C, Lomova A, Lassen A, Friedman M, Chmielowski B, Ribas A, Graeber TG. CRAF R391W is a melanoma driver oncogene. Scientific Reports. 6: 27454. PMID 27273450 DOI: 10.1038/Srep27454  0.256
2018 Smith BA, Balanis NG, Nanjundiah A, Sheu KM, Tsai BL, Zhang Q, Park JW, Thompson M, Huang J, Witte ON, Graeber TG. A Human Adult Stem Cell Signature Marks Aggressive Variants across Epithelial Cancers. Cell Reports. 24: 3353-3366.e5. PMID 30232014 DOI: 10.1016/J.Celrep.2018.08.062  0.256
2019 Smith BA, Balanis NG, Tsai B, Park J, Zhang H, Said JW, Graeber TG, Witte ON, Chin* AI. MP57-09 MOLECULAR PROFILING OF SMALL CELL BLADDER CANCER: IMPLICATIONS FOR IMMUNOTHERAPEUTIC STRATEGIES Journal of Urology. 201. DOI: 10.1097/01.Ju.0000556626.19138.D3  0.255
2016 Zaretsky JM, Garcia-Diaz A, Shin DS, Escuin-Ordinas H, Hugo W, Hu-Lieskovan S, Torrejon DY, Abril-Rodriguez G, Sandoval S, Barthly L, Saco J, Homet Moreno B, Mezzadra R, Chmielowski B, Ruchalski K, ... ... Graeber TG, et al. Mutations Associated with Acquired Resistance to PD-1 Blockade in Melanoma. The New England Journal of Medicine. PMID 27433843 DOI: 10.1056/Nejmoa1604958  0.254
2018 Momcilovic M, Bailey ST, Lee JT, Fishbein MC, Braas D, Go J, Graeber TG, Parlati F, Demo S, Li R, Walser TC, Gricowski M, Shuman R, Ibarra J, Fridman D, et al. The GSK3 Signaling Axis Regulates Adaptive Glutamine Metabolism in Lung Squamous Cell Carcinoma. Cancer Cell. 33: 905-921.e5. PMID 29763624 DOI: 10.1016/J.Ccell.2018.04.002  0.253
2020 Bayley N, Tse C, Zhu H, Yan W, Gosa L, Baufeld L, Ta L, Prins R, Yong W, Cloughesy T, Liau L, Graeber T, Nathanson D. TAMI-48. ENGRAFTMENT PHENOTYPES IN PRECLINICAL MODEL SYSTEMS REVEAL A FUNCTIONAL SUBGROUP OF PATIENT TUMORS DEPENDENT ON THE BRAIN TUMOR MICROENVIRONMENT FOR GROWTH Neuro-Oncology. 22: ii223-ii223. DOI: 10.1093/neuonc/noaa215.935  0.25
2018 Bayley N, Baufeld L, Gosa L, Morrow D, Tse C, Balanis N, Yan W, Cloughesy T, Liau L, Graeber T, Nathanson D. TMOD-03. GLIOMAPDOX: A MOLECULARLY DIVERSE LIBRARY OF DIRECT-FROM-PATIENT ORTHOTOPIC GLIOMA XENOGRAFTS RECAPITULATES INTRATUMOR HETEROGENEITY Neuro-Oncology. 20: vi268-vi269. DOI: 10.1093/Neuonc/Noy148.1116  0.25
2011 Rubbi L, Titz B, Brown L, Galvan E, Komisopoulou E, Chen SS, Low T, Tahmasian M, Skaggs B, Müschen M, Pellegrini M, Graeber TG. Global phosphoproteomics reveals crosstalk between Bcr-Abl and negative feedback mechanisms controlling Src signaling. Science Signaling. 4: ra18. PMID 21447799 DOI: 10.1126/Scisignal.2001314  0.243
2018 Balanis NG, Graeber TG. Making Mistakes Empowers Cancer Cells. Trends in Cancer. 4: 461-463. PMID 29937042 DOI: 10.1016/j.trecan.2018.05.001  0.242
2020 Court CM, Hou S, Liu L, Winograd P, DiPardo BJ, Liu SX, Chen PJ, Zhu Y, Smalley M, Zhang R, Sadeghi S, Finn RS, Kaldas FM, Busuttil RW, Zhou XJ, ... ... Graeber TG, et al. Somatic copy number profiling from hepatocellular carcinoma circulating tumor cells. Npj Precision Oncology. 4: 16. PMID 33594215 DOI: 10.1038/s41698-020-0123-0  0.241
2014 Escuin-Ordinas H, Atefi M, Fu Y, Cass A, Ng C, Huang RR, Yashar S, Comin-Anduix B, Avramis E, Cochran AJ, Marais R, Lo RS, Graeber TG, Herschman HR, Ribas A. COX-2 inhibition prevents the appearance of cutaneous squamous cell carcinomas accelerated by BRAF inhibitors. Molecular Oncology. 8: 250-60. PMID 24345644 DOI: 10.1016/J.Molonc.2013.11.005  0.241
2013 Swaminathan S, Huang C, Geng H, Chen Z, Harvey R, Kang H, Ng C, Titz B, Hurtz C, Sadiyah MF, Nowak D, Thoennissen GB, Rand V, Graeber TG, Koeffler HP, et al. BACH2 mediates negative selection and p53-dependent tumor suppression at the pre-B cell receptor checkpoint. Nature Medicine. 19: 1014-22. PMID 23852341 DOI: 10.1038/Nm.3247  0.238
2005 Skaggs BJ, Burgess MR, Gorre ME, Graeber TG, Sawyers CL. Altered Oncogenic Fitness of Imatinib- and Dasatinib-Resistant BCR-ABL Mutants Is Due to Differential Intrinsic Kinase Activity and Signaling Pathway Selection Defined by Phosphoproteome Profiling. Blood. 106: 692-692. DOI: 10.1182/Blood.V106.11.692.692  0.238
2020 Remacle F, Graeber TG, Levine RD. Thermodynamic energetics underlying genomic instability and whole-genome doubling in cancer. Proceedings of the National Academy of Sciences of the United States of America. PMID 32694208 DOI: 10.1073/Pnas.1920870117  0.237
2013 McHardy I, Goudarzi M, Tong M, Ruegger P, Horvath S, Sonnenburg J, Graeber T, Huttenhower C, Borneman J, McGovern DP, Fornace A, Braun J. Tu1983 Comprehensive Inter-Omic Analysis Reveals Exquisite Metabolite-Driven Microbial Relationships Gastroenterology. 144: S-896-S-897. DOI: 10.1016/S0016-5085(13)63339-9  0.235
2011 Poulikakos PI, Persaud Y, Janakiraman M, Kong X, Ng C, Moriceau G, Shi H, Atefi M, Titz B, Gabay MT, Salton M, Dahlman KB, Tadi M, Wargo JA, Flaherty KT, ... ... Graeber TG, et al. RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E). Nature. 480: 387-90. PMID 22113612 DOI: 10.1038/Nature10662  0.233
2016 Li X, LeBlanc J, Elashoff D, McHardy I, Tong M, Roth B, Ippoliti A, Barron G, McGovern D, McDonald K, Newberry R, Graeber T, Horvath S, Goodglick L, Braun J. Microgeographic Proteomic Networks of the Human Colonic Mucosa and Their Association With Inflammatory Bowel Disease. Cellular and Molecular Gastroenterology and Hepatology. 2: 567-583. PMID 28174738 DOI: 10.1016/J.Jcmgh.2016.05.003  0.233
2023 Roider E, Lakatos AIT, McConnell AM, Wang P, Mueller A, Kawakami A, Tsoi J, Szabolcs BL, Ascsillán AA, Suita Y, Igras V, Lo JA, Hsiao JJ, Lapides R, Pál DMP, ... ... Graeber TG, et al. MITF regulates IDH1 and NNT and drives a transcriptional program protecting cutaneous melanoma from reactive oxygen species. Biorxiv : the Preprint Server For Biology. PMID 38014031 DOI: 10.1101/2023.11.10.564582  0.233
2011 Swaminathan S, Huang C, Titz B, Buchner M, Geng H, Graeber TG, Willman CL, Igarashi K, Melnick A, Muschen M. BACH2 Mediates Early B Cell Differentiation and Oncogene-Induced Senescence in Acute Lymphoblastic Leukemia Blood. 118: 562-562. DOI: 10.1182/Blood.V118.21.562.562  0.232
2002 Matei D, Graeber TG, Baldwin RL, Karlan BY, Rao J, Chang DD. Gene expression in epithelial ovarian carcinoma. Oncogene. 21: 6289-98. PMID 12214269 DOI: 10.1038/Sj.Onc.1205785  0.232
2017 Xu S, Catapang A, Braas D, Stiles L, Lee JT, Graeber TG, Damoiseaux R, Shirihai O, Herschman HR. Abstract B37: Targeting the energy generation triangle to achieve synthetic lethality for treatment of hepatocellular carcinoma Molecular Cancer Therapeutics. 16. DOI: 10.1158/1538-8514.Synthleth-B37  0.231
2013 Ahler E, Sullivan WJ, Cass A, Braas D, York AG, Bensinger SJ, Graeber TG, Christofk HR. Doxycycline Alters Metabolism and Proliferation of Human Cell Lines Plos One. 8. PMID 23741339 DOI: 10.1371/Journal.Pone.0064561  0.231
2011 Duy C, Hurtz C, Shojaee S, Cerchietti L, Geng H, Swaminathan S, Klemm L, Kweon SM, Nahar R, Braig M, Park E, Kim YM, Hofmann WK, Herzog S, Jumaa H, ... ... Graeber TG, et al. BCL6 enables Ph+ acute lymphoblastic leukaemia cells to survive BCR-ABL1 kinase inhibition. Nature. 473: 384-8. PMID 21593872 DOI: 10.1038/Nature09883  0.23
2015 Chen Z, Shojaee S, Buchner M, Geng H, Lee JW, Klemm L, Titz B, Graeber TG, Park E, Tan YX, Satterthwaite A, Paietta E, Hunger SP, Willman CL, Melnick A, et al. Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia. Nature. 521: 357-61. PMID 25799995 DOI: 10.1038/Nature14231  0.23
2005 Ellwood-Yen K, Graeber TG, Wongvipat J, Iruela-Arispe ML, Zhang J, Matusik R, Thomas GV, Sawyers CL. Myc-driven murine prostate cancer shares molecular features with human prostate tumors Cancer Cell. 8: 485. DOI: 10.1016/J.Ccr.2005.11.010  0.226
2021 Kim YJ, Sheu KM, Tsoi J, Abril-Rodriguez G, Medina E, Grasso CS, Torrejon DY, Champhekar AS, Litchfield K, Swanton C, Speiser DE, Scumpia PO, Hoffmann A, Graeber TG, Puig-Saus C, et al. Melanoma dedifferentiation induced by interferon-gamma epigenetic remodeling in response to anti-PD-1 therapy. The Journal of Clinical Investigation. PMID 33914706 DOI: 10.1172/JCI145859  0.225
2012 Li X, LeBlanc JF, Elashoff D, McHardy I, Tong M, Roth B, Ippoliti A, Graeber T, Goodglick L, Braun J. 44 Mucosal Surface Sampling and Metaproteomic Analysis Identify Disease-Related Biologic Neighborhoods Gastroenterology. 142: S-12. DOI: 10.1016/S0016-5085(12)60044-4  0.224
2021 Bayley N, Tse C, Zhu H, Ta L, Baufeld L, Gosa L, Yan W, Prins R, Yong W, Cloughesy T, Liau L, Graeber T, Nathanson D. EPCO-10. INTRATUMORAL HETEROGENEITY OF ENVIRONMENT-INDUCED EXPRESSION PROGRAMS IN GLIOMA PATIENTS AND DERIVED MODEL SYSTEMS Neuro-Oncology. 23: vi3-vi3. DOI: 10.1093/neuonc/noab196.009  0.22
2015 Mok S, Tsoi J, Koya RC, Hu-Lieskovan S, West BL, Bollag G, Graeber TG, Ribas A. Inhibition of colony stimulating factor-1 receptor improves antitumor efficacy of BRAF inhibition. Bmc Cancer. 15: 356. PMID 25939769 DOI: 10.1186/s12885-015-1377-8  0.219
2021 Song K, Minami JK, Huang A, Dehkordi SR, Lomeli SH, Luebeck J, Goodman MH, Moriceau G, Krijgsman O, Dharanipragada P, Ridgley T, Crosson WP, Salazar J, Pazol E, Karin G, ... ... Graeber TG, et al. Plasticity of extrachromosomal and intrachromosomal BRAF amplifications in overcoming targeted therapy dosage challenges. Cancer Discovery. PMID 34930786 DOI: 10.1158/2159-8290.CD-20-0936  0.218
2006 Skaggs BJ, Gorre ME, Ryvkin A, Burgess MR, Xie Y, Han Y, Komisopoulou E, Brown LM, Loo JA, Landaw EM, Sawyers CL, Graeber TG. Phosphorylation of the ATP-binding loop directs oncogenicity of drug-resistant BCR-ABL mutants. Proceedings of the National Academy of Sciences of the United States of America. 103: 19466-71. PMID 17164333 DOI: 10.1073/Pnas.0609239103  0.215
2016 Wu TH, Sagullo E, Case D, Zheng X, Li Y, Hong JS, TeSlaa T, Patananan AN, McCaffery JM, Niazi K, Braas D, Koehler CM, Graeber TG, Chiou PY, Teitell MA. Mitochondrial Transfer by Photothermal Nanoblade Restores Metabolite Profile in Mammalian Cells. Cell Metabolism. 23: 921-929. PMID 27166949 DOI: 10.1016/J.Cmet.2016.04.007  0.215
2020 Kim YJ, Sheu KM, Tsoi J, Abril-Rodriguez G, Grasso C, Hoffmann A, Smale ST, Graeber TG, Puig-Saus C, Ribas A. Abstract 3155: Interferon-gamma-induced melanoma plasticity and response to PD-1 blockade therapy Cancer Research. 80: 3155-3155. DOI: 10.1158/1538-7445.Am2020-3155  0.212
2019 Waters LR, Ahsan FM, Ten Hoeve J, Hong JS, Kim DNH, Minasyan A, Braas D, Graeber TG, Zangle TA, Teitell MA. Ampk regulates IgD expression but not energy stress with B cell activation. Scientific Reports. 9: 8176. PMID 31160601 DOI: 10.1038/s41598-019-43985-y  0.212
2013 Williams KJ, Argus JP, Zhu Y, Wilks MQ, Marbois BN, York AG, Kidani Y, Pourzia AL, Akhavan D, Lisiero DN, Komisopoulou E, Henkin AH, Soto H, Chamberlain BT, Vergnes L, ... ... Graeber TG, et al. An essential requirement for the SCAP/SREBP signaling axis to protect cancer cells from lipotoxicity. Cancer Research. 73: 2850-62. PMID 23440422 DOI: 10.1158/0008-5472.Can-13-0382-T  0.211
2018 Xiao G, Chan LN, Klemm L, Braas D, Chen Z, Geng H, Zhang QC, Aghajanirefah A, Cosgun KN, Sadras T, Lee J, Mirzapoiazova T, Salgia R, Ernst T, Hochhaus A, ... ... Graeber TG, et al. B-Cell-Specific Diversion of Glucose Carbon Utilization Reveals a Unique Vulnerability in B Cell Malignancies. Cell. PMID 29551267 DOI: 10.1016/J.Cell.2018.02.048  0.211
2010 Zimman A, Chen SS, Komisopoulou E, Titz B, Martínez-Pinna R, Kafi A, Berliner JA, Graeber TG. Activation of aortic endothelial cells by oxidized phospholipids: a phosphoproteomic analysis. Journal of Proteome Research. 9: 2812-24. PMID 20307106 DOI: 10.1021/Pr901194X  0.21
2018 Court CM, Ankeny JS, Sho S, Winograd P, Hou S, Song M, Wainberg ZA, Girgis MD, Graeber TG, Agopian VG, Tseng HR, Tomlinson JS. Circulating Tumor Cells Predict Occult Metastatic Disease and Prognosis in Pancreatic Cancer. Annals of Surgical Oncology. PMID 29442211 DOI: 10.1245/S10434-017-6290-8  0.208
2023 Minami JK, Morrow D, Bayley NA, Fernandez EG, Salinas JJ, Tse C, Zhu H, Su B, Plawat R, Jones A, Sammarco A, Liau LM, Graeber TG, Williams KJ, Cloughesy TF, et al. CDKN2A deletion remodels lipid metabolism to prime glioblastoma for ferroptosis. Cancer Cell. PMID 37236196 DOI: 10.1016/j.ccell.2023.05.001  0.205
2003 Bleharski JR, Li H, Meinken C, Graeber TG, Ochoa MT, Yamamura M, Burdick A, Sarno EN, Wagner M, Röllinghoff M, Rea TH, Colonna M, Stenger S, Bloom BR, Eisenberg D, et al. Use of genetic profiling in leprosy to discriminate clinical forms of the disease. Science (New York, N.Y.). 301: 1527-30. PMID 12970564 DOI: 10.1126/Science.1087785  0.205
2016 Titz B, Lomova A, Le A, Hugo W, Kong X, Ten Hoeve J, Friedman M, Shi H, Moriceau G, Song C, Hong A, Atefi M, Li R, Komisopoulou E, Ribas A, ... ... Graeber TG, et al. JUN dependency in distinct early and late BRAF inhibition adaptation states of melanoma. Cell Discovery. 2: 16028. PMID 27648299 DOI: 10.1038/Celldisc.2016.28  0.205
2014 Müller J, Krijgsman O, Tsoi J, Robert L, Hugo W, Song C, Kong X, Possik PA, Cornelissen-Steijger PD, Foppen MH, Kemper K, Goding CR, McDermott U, Blank C, Haanen J, ... Graeber TG, et al. Low MITF/AXL ratio predicts early resistance to multiple targeted drugs in melanoma. Nature Communications. 5: 5712. PMID 25502142 DOI: 10.1038/ncomms6712  0.205
2017 Su Y, Wei W, Robert L, Xue M, Tsoi J, Garcia-Diaz A, Homet Moreno B, Kim J, Ng RH, Lee JW, Koya RC, Comin-Anduix B, Graeber TG, Ribas A, Heath JR. Single-cell analysis resolves the cell state transition and signaling dynamics associated with melanoma drug-induced resistance. Proceedings of the National Academy of Sciences of the United States of America. PMID 29229836 DOI: 10.1073/Pnas.1712064115  0.204
2011 Graeber TG, VanHook AM. Science Signaling Podcast: 29 March 2011 Science Signaling. 4. DOI: 10.1126/Scisignal.2001941  0.203
2000 Graeber TG, Shuai K. Rapid gene repression triggered by interleukin-6 at the onset of monocyte differentiation. Biochemical and Biophysical Research Communications. 267: 863-9. PMID 10673382 DOI: 10.1006/BBRC.1999.2041  0.201
2014 Wong DJ, Robert L, Atefi MS, Lassen A, Avarappatt G, Cerniglia M, Avramis E, Tsoi J, Foulad D, Graeber TG, Comin-Anduix B, Samatar A, Lo RS, Ribas A. Antitumor activity of the ERK inhibitor SCH722984 against BRAF mutant, NRAS mutant and wild-type melanoma. Molecular Cancer. 13: 194. PMID 25142146 DOI: 10.1186/1476-4598-13-194  0.201
2014 Mok S, Koya RC, Tsui C, Xu J, Robert L, Wu L, Graeber TG, West BL, Bollag G, Ribas A. Inhibition of CSF-1 receptor improves the antitumor efficacy of adoptive cell transfer immunotherapy. Cancer Research. 74: 153-61. PMID 24247719 DOI: 10.1158/0008-5472.CAN-13-1816  0.199
2010 Graeber TG, Heath JR, Skaggs BJ, Phelps ME, Remacle F, Levine RD. Maximal entropy inference of oncogenicity from phosphorylation signaling. Proceedings of the National Academy of Sciences of the United States of America. 107: 6112-7. PMID 20224037 DOI: 10.1073/Pnas.1001149107  0.199
2014 Graham NA, Graeber TG. Complexity of metastasis-associated SDF-1 ligand signaling in breast cancer stem cells. Proceedings of the National Academy of Sciences of the United States of America. 111: 7503-4. PMID 24828528 DOI: 10.1073/pnas.1405991111  0.197
2014 Thai M, Graham NA, Braas D, Nehil M, Komisopoulou E, Kurdistani SK, McCormick F, Graeber TG, Christofk HR. Adenovirus E4ORF1-induced MYC activation promotes host cell anabolic glucose metabolism and virus replication. Cell Metabolism. 19: 694-701. PMID 24703700 DOI: 10.1016/J.Cmet.2014.03.009  0.194
2013 Zimman A, Berliner JA, Graeber TG. Phosphoproteomic analysis of aortic endothelial cells activated by oxidized phospholipids. Methods in Molecular Biology (Clifton, N.J.). 1000: 53-69. PMID 23585084 DOI: 10.1007/978-1-62703-405-0_5  0.193
2016 Court CM, Ankeny JS, Sho S, Hou S, Li Q, Hsieh C, Song M, Liao X, Rochefort MM, Wainberg Z, Graeber TG, Tseng HR, Tomlinson JS. Reality of Single Circulating Tumor Cell Sequencing for Molecular Diagnostics in Pancreatic Cancer. The Journal of Molecular Diagnostics : Jmd. PMID 27375074 DOI: 10.1016/J.Jmoldx.2016.03.006  0.193
2010 Tumeh PC, Koya RC, Chodon T, Graham NA, Graeber TG, Comin-Anduix B, Ribas A. The impact of ex vivo clinical grade activation protocols on human T-cell phenotype and function for the generation of genetically modified cells for adoptive cell transfer therapy. Journal of Immunotherapy (Hagerstown, Md. : 1997). 33: 759-68. PMID 20842061 DOI: 10.1097/CJI.0b013e3181f1d644  0.191
2015 Fu X, Chin RM, Vergnes L, Hwang H, Deng G, Xing Y, Pai MY, Li S, Ta L, Fazlollahi F, Chen C, Prins RM, Teitell MA, Nathanson DA, Lai A, ... ... Graeber TG, et al. 2-Hydroxyglutarate Inhibits ATP Synthase and mTOR Signaling. Cell Metabolism. PMID 26190651 DOI: 10.1016/J.Cmet.2015.06.009  0.191
2023 Udutha S, Taglang C, Batsios G, Gillespie AM, Tran M, Ronen SM, Ten Hoeve J, Graeber TG, Viswanath P. Telomerase reverse transcriptase induces targetable alterations in glutathione and nucleotide biosynthesis in glioblastomas. Biorxiv : the Preprint Server For Biology. PMID 38014170 DOI: 10.1101/2023.11.14.566937  0.191
2016 Krall AS, Xu S, Graeber TG, Braas D, Christofk HR. Asparagine promotes cancer cell proliferation through use as an amino acid exchange factor. Nature Communications. 7: 11457. PMID 27126896 DOI: 10.1038/Ncomms11457  0.189
2015 Chan LN, Chen Z, Braas D, Geng H, Hurtz C, Shojaee S, Cazzaniga V, Ng C, Ernst T, Hochhaus A, Kornblau SM, Cazzaniga G, Liu G, Milne T, Koeffler HP, ... ... Graeber TG, et al. B-Lymphoid Transcription Factors Restrict Glycolytic Energy Supply for Oncogenic Signaling Blood. 126: 1255-1255. DOI: 10.1182/Blood.V126.23.1255.1255  0.189
2018 Braun J, Brislawn C, Casero D, Purvine S, Scott JJ, White RA, Arze C, Lloyd-Price J, Vlamakis H, Xavier R, Huttenhower C, Graeber T, Jansson J. 1100 - Dynamics of the Microbial Metaproteome in Inflammatory Bowel Disease Gastroenterology. 154: S-217. DOI: 10.1016/S0016-5085(18)31115-6  0.185
2015 Inkeles MS, Scumpia PO, Swindell WR, Lopez D, Teles RM, Graeber TG, Meller S, Homey B, Elder JT, Gilliet M, Modlin RL, Pellegrini M. Comparison of molecular signatures from multiple skin diseases identifies mechanisms of immunopathogenesis. The Journal of Investigative Dermatology. 135: 151-9. PMID 25111617 DOI: 10.1038/Jid.2014.352  0.185
2015 Ting PY, Damoiseaux R, Titz B, Bradley KA, Graeber TG, Fernández-Vega V, Bannister TD, Chase P, Nair R, Scampavia L, Hodder P, Spicer TP, Colicelli J. Identification of small molecules that disrupt signaling between ABL and its positive regulator RIN1. Plos One. 10: e0121833. PMID 25811598 DOI: 10.1371/Journal.Pone.0121833  0.183
2015 Goodwin JF, Kothari V, Drake JM, Zhao S, Dylgjeri E, Dean JL, Schiewer MJ, McNair C, Magee MS, Den RB, Zhu Z, Graham NA, Vashisht AA, Wohlschlegel JA, Graeber TG, et al. Abstract 1860: DNA-PK-mediated transcriptional regulation drives tumor progression and metastasis Endocrinology. 75: 1860-1860. DOI: 10.1158/1538-7445.Am2015-1860  0.183
2020 Gang EJ, Kim HN, Hsieh YT, Ruan Y, Ogana H, Pham J, Lee S, Geng H, Park E, Klemm L, Willman CL, Carroll WL, Mittelman SD, Orgel E, Oberley MJ, ... ... Graeber T, et al. Integrin α6 mediates drug resistance of acute lymphoblastic B-cell leukemia. Blood. PMID 32219444 DOI: 10.1182/Blood.2019001417  0.182
2017 Chan LN, Chen Z, Braas D, Lee JW, Xiao G, Geng H, Cosgun KN, Hurtz C, Shojaee S, Cazzaniga V, Schjerven H, Ernst T, Hochhaus A, Kornblau SM, Konopleva M, ... ... Graeber TG, et al. Metabolic gatekeeper function of B-lymphoid transcription factors. Nature. 1-5. PMID 28192788 DOI: 10.1038/Nature21076  0.177
2015 Goodwin JF, Kothari V, Drake JM, Zhao S, Dylgjeri E, Dean JL, Schiewer MJ, McNair C, Jones JK, Aytes A, Magee MS, Snook AE, Zhu Z, Den RB, Birbe RC, ... ... Graeber TG, et al. DNA-PKcs-Mediated Transcriptional Regulation Drives Prostate Cancer Progression and Metastasis. Cancer Cell. 28: 97-113. PMID 26175416 DOI: 10.1016/J.Ccell.2015.06.004  0.177
2018 Garrett M, Sperry J, Braas D, Yan W, Le TM, Mottahedeh J, Ludwig K, Eskin A, Qin Y, Levy R, Breunig JJ, Pajonk F, Graeber TG, Radu CG, Christofk H, et al. Metabolic characterization of isocitrate dehydrogenase (IDH) mutant and IDH wildtype gliomaspheres uncovers cell type-specific vulnerabilities. Cancer & Metabolism. 6: 4. PMID 29692895 DOI: 10.1186/S40170-018-0177-4  0.176
2016 Homet Moreno B, Zaretsky JM, Garcia-Diaz A, Tsoi J, Parisi G, Robert L, Meeth K, Ndoye A, Bosenberg MW, Weeraratna AT, Graeber TG, Comin-Anduix B, Hu-Lieskovan S, Ribas A. Response to programmed cell death-1 blockade in a murine melanoma syngeneic model requires costimulation, CD4, and CD8 T cells. Cancer Immunology Research. PMID 27589875 DOI: 10.1158/2326-6066.CIR-16-0060  0.174
2018 Cheng LC, Li Z, Graeber TG, Graham NA, Drake JM. Phosphopeptide Enrichment Coupled with Label-free Quantitative Mass Spectrometry to Investigate the Phosphoproteome in Prostate Cancer. Journal of Visualized Experiments : Jove. PMID 30124664 DOI: 10.3791/57996  0.172
2015 Robert L, Tsoi J, Wang X, Emerson R, Homet B, Chodon T, Mok S, Huang RR, Cochran AJ, Comin-Anduix B, Koya RC, Graeber TG, Robins H, Ribas A. Erratum: CTLA4 blockade broadens the peripheral T-cell receptor repertoire (Clinical Cancer Research (2014) 20 (2424-2432)) Clinical Cancer Research. 21. PMID 26180060 DOI: 10.1158/1078-0432.Ccr-15-1088  0.171
2015 Hu-Lieskovan S, Mok S, Homet Moreno B, Tsoi J, Robert L, Goedert L, Pinheiro EM, Koya RC, Graeber TG, Comin-Anduix B, Ribas A. Improved antitumor activity of immunotherapy with BRAF and MEK inhibitors in BRAFV600E melanoma Science Translational Medicine. 7. DOI: 10.1126/scitranslmed.aaa4691  0.17
2005 Graeber TG, Sawyers CL. Cross-species comparisons of cancer signaling. Nature Genetics. 37: 7-8. PMID 15624012 DOI: 10.1038/ng0105-7  0.17
2020 Bennett NK, Nguyen MK, Darch MA, Nakaoka HJ, Cousineau D, Ten Hoeve J, Graeber TG, Schuelke M, Maltepe E, Kampmann M, Mendelsohn BA, Nakamura JL, Nakamura K. Defining the ATPome reveals cross-optimization of metabolic pathways. Nature Communications. 11: 4319. PMID 32859923 DOI: 10.1038/S41467-020-18084-6  0.17
2019 Palaskas NJ, Garcia JD, Shirazi R, Shin DS, Puig-Saus C, Braas D, Ribas A, Graeber TG. Global alteration of T-lymphocyte metabolism by PD-L1 checkpoint involves a block of de novo nucleoside phosphate synthesis. Cell Discovery. 5: 62. PMID 31798961 DOI: 10.1038/s41421-019-0130-x  0.17
2020 Li S, Ma F, Yokota T, Garcia G, Palermo A, Wang Y, Farrell C, Wang YC, Wu R, Zhou Z, Pan C, Morselli M, Teitell MA, Ryazantsev S, Fishbein GA, ... ... Graeber TG, et al. Metabolic reprogramming and epigenetic changes of vital organs in SARS-CoV-2 induced systemic toxicity. Jci Insight. PMID 33284134 DOI: 10.1172/jci.insight.145027  0.17
2015 Thai M, Thaker SK, Feng J, Du Y, Hu H, Ting Wu T, Graeber TG, Braas D, Christofk HR. MYC-induced reprogramming of glutamine catabolism supports optimal virus replication. Nature Communications. 6: 8873. PMID 26561297 DOI: 10.1038/Ncomms9873  0.167
2010 Titz B, Low T, Komisopoulou E, Chen SS, Rubbi L, Graeber TG. The proximal signaling network of the BCR-ABL1 oncogene shows a modular organization Oncogene. 29: 5895-5910. PMID 20697350 DOI: 10.1038/Onc.2010.331  0.165
2014 Zimman A, Titz B, Komisopoulou E, Biswas S, Graeber TG, Podrez EA. Phosphoproteomic analysis of platelets activated by pro-thrombotic oxidized phospholipids and thrombin. Plos One. 9: e84488. PMID 24400094 DOI: 10.1371/journal.pone.0084488  0.163
2017 Sho S, Court CM, Winograd P, Lee S, Hou S, Graeber TG, Tseng HR, Tomlinson JS. Precision oncology using a limited number of cells: optimization of whole genome amplification products for sequencing applications. Bmc Cancer. 17: 457. PMID 28666423 DOI: 10.1186/S12885-017-3447-6  0.162
2013 Kidani Y, Elsaesser H, Hock MB, Vergnes L, Williams KJ, Argus JP, Marbois BN, Komisopoulou E, Wilson EB, Osborne TF, Graeber TG, Reue K, Brooks DG, Bensinger SJ. Sterol regulatory element-binding proteins are essential for the metabolic programming of effector T cells and adaptive immunity. Nature Immunology. 14: 489-99. PMID 23563690 DOI: 10.1038/Ni.2570  0.16
2019 Vijayaraj P, Minasyan A, Durra A, Karumbayaram S, Mehrabi M, Aros CJ, Ahadome SD, Shia DW, Chung K, Sandlin JM, Darmawan KF, Bhatt KV, Manze CC, Paul MK, Wilkinson DC, ... ... Graeber TG, et al. Modeling Progressive Fibrosis with Pluripotent Stem Cells Identifies an Anti-fibrotic Small Molecule. Cell Reports. 29: 3488-3505.e9. PMID 31825831 DOI: 10.1016/J.Celrep.2019.11.019  0.154
2016 Shin DS, Zaretsky JM, Escuin-Ordinas H, Garcia-Diaz A, Hu-Lieskovan S, Kalbasi A, Grasso CS, Hugo W, Sandoval S, Torrejon DY, Palaskas N, Abril Rodriguez G, Parisi G, Azhdam A, Chmielowski B, ... ... Graeber TG, et al. Primary Resistance to PD-1 Blockade Mediated by JAK½ Mutations. Cancer Discovery. PMID 27903500 DOI: 10.1158/2159-8290.CD-16-1223  0.154
2012 Liu PT, Wheelwright M, Teles R, Komisopoulou E, Edfeldt K, Ferguson B, Mehta MD, Vazirnia A, Rea TH, Sarno EN, Graeber TG, Modlin RL. MicroRNA-21 targets the vitamin D-dependent antimicrobial pathway in leprosy. Nature Medicine. 18: 267-73. PMID 22286305 DOI: 10.1038/Nm.2584  0.152
2013 McHardy IH, Goudarzi M, Tong M, Ruegger PM, Schwager E, Weger JR, Graeber TG, Sonnenburg JL, Horvath S, Huttenhower C, McGovern DP, Fornace AJ, Borneman J, Braun J. Integrative analysis of the microbiome and metabolome of the human intestinal mucosal surface reveals exquisite inter-relationships. Microbiome. 1: 17. PMID 24450808 DOI: 10.1186/2049-2618-1-17  0.152
2019 Dhandapani PK, Begines-Moreno IM, Brea-Calvo G, Gärtner U, Graeber TG, Javier Sanchez G, Morty RE, Schönig K, Hoeve JT, Wietelmann A, Braun T, Jacobs HT, Szibor M. Hyperoxia but not AOX expression mitigates pathological cardiac remodeling in a mouse model of inflammatory cardiomyopathy. Scientific Reports. 9: 12741. PMID 31484989 DOI: 10.1038/s41598-019-49231-9  0.146
2016 Ankeny JS, Court CM, Hou S, Li Q, Song M, Wu D, Chen JF, Lee T, Lin M, Sho S, Rochefort MM, Girgis MD, Yao J, Wainberg ZA, Muthusamy VR, ... ... Graeber TG, et al. Circulating tumour cells as a biomarker for diagnosis and staging in pancreatic cancer. British Journal of Cancer. 114: 1367-1375. PMID 27300108 DOI: 10.1038/bjc.2016.121  0.145
2019 Paz H, Tsoi J, Kalbasi A, Grasso CS, McBride WH, Schaue D, Butterfield LH, Maurer DM, Ribas A, Graeber TG, Economou JS. Interleukin 32 expression in human melanoma. Journal of Translational Medicine. 17: 113. PMID 30953519 DOI: 10.1186/S12967-019-1862-Y  0.144
2014 Tong M, McHardy I, Ruegger P, Goudarzi M, Kashyap PC, Haritunians T, Li X, Graeber TG, Schwager E, Huttenhower C, Fornace AJ, Sonnenburg JL, McGovern DP, Borneman J, Braun J. Reprograming of gut microbiome energy metabolism by the FUT2 Crohn's disease risk polymorphism. The Isme Journal. 8: 2193-206. PMID 24781901 DOI: 10.1038/Ismej.2014.64  0.143
2007 Zimman A, Mouillesseaux KP, Le T, Gharavi NM, Ryvkin A, Graeber TG, Chen TT, Watson AD, Berliner JA. Vascular endothelial growth factor receptor 2 plays a role in the activation of aortic endothelial cells by oxidized phospholipids. Arteriosclerosis, Thrombosis, and Vascular Biology. 27: 332-8. PMID 17110601 DOI: 10.1161/01.Atv.0000252842.57585.Df  0.143
2016 Patananan AN, Wu T, Sagullo E, Case D, Zheng X, Li Y, Hong JS, TeSlaa T, McCaffery JM, Niazi K, Braas D, Koehler CM, Graeber TG, Chiou P, Teitell MA. Mitochondrial Transfer by Photothermal Nanoblade Restores Respiration in Mammalian Cells with Dysfunctional Mitochondria Biophysical Journal. 110: 471a-472a. DOI: 10.1016/J.Bpj.2015.11.2523  0.142
1997 Derevianko A, D'Amico R, Graeber T, Keeping H, Simms HH. Endogenous PMN-derived reactive oxygen intermediates provide feedback regulation on respiratory burst signal transduction. Journal of Leukocyte Biology. 62: 268-76. PMID 9261341 DOI: 10.1002/jlb.62.2.268  0.138
1995 Giaccialia AJ, Tsai M, Lowe SW, Graeber TG. 159 Hypoxia acts as a selective pressure for the loss of wild-type P53 in solid tumor development International Journal of Radiation Oncology*Biology*Physics. 32: 220. DOI: 10.1016/0360-3016(95)97822-I  0.134
2012 Schenk M, Krutzik SR, Sieling PA, Lee DJ, Teles RM, Ochoa MT, Komisopoulou E, Sarno EN, Rea TH, Graeber TG, Kim S, Cheng G, Modlin RL. NOD2 triggers an interleukin-32-dependent human dendritic cell program in leprosy. Nature Medicine. 18: 555-63. PMID 22447076 DOI: 10.1038/Nm.2650  0.133
2003 Strong M, Graeber TG, Beeby M, Pellegrini M, Thompson MJ, Yeates TO, Eisenberg D. Visualization and interpretation of protein networks in Mycobacterium tuberculosis based on hierarchical clustering of genome-wide functional linkage maps. Nucleic Acids Research. 31: 7099-109. PMID 14654685 DOI: 10.1093/Nar/Gkg924  0.132
2015 Wong DJ, Robert L, Atefi MS, Lassen A, Avarappatt G, Cerniglia M, Avramis E, Tsoi J, Foulad D, Graeber TG, Comin-Anduix B, Samatar A, Lo RS, Ribas A. Erratum to: Antitumor activity of the ERK inhibitor SCH722984 against BRAF mutant, NRAS mutant and wild-type melanoma. Molecular Cancer. 14: 128. PMID 26134498 DOI: 10.1186/S12943-015-0393-2  0.132
2011 Li X, LeBlanc J, Truong A, Vuthoori R, Chen SS, Lustgarten JL, Roth B, Allard J, Ippoliti A, Presley LL, Borneman J, Bigbee WL, Gopalakrishnan V, Graeber TG, Elashoff D, et al. A metaproteomic approach to study human-microbial ecosystems at the mucosal luminal interface. Plos One. 6: e26542. PMID 22132074 DOI: 10.1371/Journal.Pone.0026542  0.128
2014 Fu X, Chin RM, Vergnes L, Hwang H, Deng G, Xing Y, Pai MY, Li S, Ta L, Fazlollahi F, Chen C, Prins RM, Teitell MA, Nathanson DA, Lai A, ... ... Graeber TG, et al. 2-Hydroxyglutarate Inhibits ATP Synthase and mTOR Signaling Cell Metabolism. DOI: 10.1016/j.cmet.2015.06.009  0.125
2013 Knight DA, Ngiow SF, Li M, Parmenter T, Mok S, Cass A, Haynes NM, Kinross K, Yagita H, Koya RC, Graeber TG, Ribas A, McArthur GA, Smyth MJ. Host immunity contributes to the anti-melanoma activity of BRAF inhibitors (Journal of Clinical Investigation (2013) 123, 3, (1371-1381) DOI: 10.1172/JCI66236) Journal of Clinical Investigation. 123: 3182. DOI: 10.1172/JCI70645  0.123
2023 Knight DA, Ngiow SF, Li M, Parmenter T, Mok S, Cass A, Haynes NM, Kinross K, Yagita H, Koya RC, Graeber TG, Ribas A, McArthur GA, Smyth MJ. Host immunity contributes to the anti-melanoma activity of BRAF inhibitors. The Journal of Clinical Investigation. 133. PMID 38099495 DOI: 10.1172/JCI177489  0.12
2015 Knight DA, Ngiow SF, Li M, Parmenter T, Mok S, Cass A, Haynes NM, Kinross K, Yagita H, Koya RC, Graeber TG, Ribas A, McArthur GA, Smyth MJ. Host immunity contributes to the anti-melanoma activity of BRAF inhibitors. The Journal of Clinical Investigation. PMID 26595810 DOI: 10.1172/JCI84828  0.12
2013 Teles RM, Graeber TG, Krutzik SR, Montoya D, Schenk M, Lee DJ, Komisopoulou E, Kelly-Scumpia K, Chun R, Iyer SS, Sarno EN, Rea TH, Hewison M, Adams JS, Popper SJ, et al. Type I interferon suppresses type II interferon-triggered human anti-mycobacterial responses. Science (New York, N.Y.). 339: 1448-53. PMID 23449998 DOI: 10.1126/Science.1233665  0.116
2023 Palermo A, Li S, Ten Hoeve J, Chellappa A, Morris A, Dillon B, Ma F, Wang Y, Cao E, Shabane B, Acín-Perez R, Petcherski A, Lusis AJ, Hazen S, Shirihai OS, ... ... Graeber TG, et al. A ketogenic diet can mitigate SARS-CoV-2 induced systemic reprogramming and inflammation. Communications Biology. 6: 1115. PMID 37923961 DOI: 10.1038/s42003-023-05478-7  0.114
1996 Derevianko A, Graeber T, D'Amico R, Simms HH. Altered oxygen tension modulates cytokine-induced signal transduction in polymorphonuclear leukocytes: Regulation of the GPLD pathway Shock. 5: 97-105. PMID 8705396 DOI: 10.1097/00024382-199602000-00003  0.113
2016 TeSlaa T, Chaikovsky AC, Lipchina I, Escobar SL, Hochedlinger K, Huang J, Graeber TG, Braas D, Teitell MA. α-Ketoglutarate Accelerates the Initial Differentiation of Primed Human Pluripotent Stem Cells. Cell Metabolism. PMID 27476976 DOI: 10.1016/J.Cmet.2016.07.002  0.112
2017 Garcia-Diaz A, Shin DS, Moreno BH, Saco J, Escuin-Ordinas H, Rodriguez GA, Zaretsky JM, Sun L, Hugo W, Wang X, Parisi G, Saus CP, Torrejon DY, Graeber TG, Comin-Anduix B, et al. Interferon Receptor Signaling Pathways Regulating PD-L1 and PD-L2 Expression. Cell Reports. 19: 1189-1201. PMID 28494868 DOI: 10.1016/j.celrep.2017.04.031  0.111
1996 Knowles R, Keeping H, Nguyen K, Graeber T, D'Amico R, Simms H. Hypoxemia/reoxygenation down-regulates interleukin-8-stimulated bactericidal activity of polymorphonuclear neutrophil by differential regulation of CD16 and CD35 mRNA expression. Surgery. 120: 382-7; discussion 38. PMID 8751608 DOI: 10.1016/S0039-6060(96)80313-8  0.109
2021 Li S, Yokota T, Wang P, Ten Hoeve J, Ma F, Le TM, Abt ER, Zhou Y, Wu R, Nanthavongdouangsy M, Rodriguez A, Wang Y, Lin YJ, Muranaka H, Sharpley M, ... ... Graeber TG, et al. The cardiomyocyte disrupts pyrimidine biosynthesis in non-myocytes to regulate heart repair. The Journal of Clinical Investigation. PMID 34813507 DOI: 10.1172/JCI149711  0.109
1998 Derevianko A, Graeber T, D'Amico R, Simms HH. The role of neutrophil-derived oxidants as second messengers in interleukin 1β-stimulated cells Shock. 10: 54-61. PMID 9688092 DOI: 10.1097/00024382-199807000-00010  0.107
2018 Chan LN, Chen Z, Braas D, Lee JW, Xiao G, Geng H, Cosgun KN, Hurtz C, Shojaee S, Cazzaniga V, Schjerven H, Ernst T, Hochhaus A, Kornblau SM, Konopleva M, ... ... Graeber TG, et al. Author Correction: Metabolic gatekeeper function of B-lymphoid transcription factors. Nature. PMID 29849140 DOI: 10.1038/S41586-018-0164-5  0.107
2005 Krutzik SR, Tan B, Li H, Ochoa MT, Liu PT, Sharfstein SE, Graeber TG, Sieling PA, Liu YJ, Rea TH, Bloom BR, Modlin RL. TLR activation triggers the rapid differentiation of monocytes into macrophages and dendritic cells. Nature Medicine. 11: 653-60. PMID 15880118 DOI: 10.1038/Nm1246  0.106
2019 Lloyd-Price J, Arze C, Ananthakrishnan AN, Schirmer M, Avila-Pacheco J, Poon TW, Andrews E, Ajami NJ, Bonham KS, Brislawn CJ, Casero D, Courtney H, Gonzalez A, Graeber TG, Hall AB, et al. Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases. Nature. 569: 655-662. PMID 31142855 DOI: 10.1038/S41586-019-1237-9  0.105
2014 Robert L, Tsoi J, Wang X, Emerson R, Homet B, Chodon T, Mok S, Huang RR, Cochran AJ, Comin-Anduix B, Koya RC, Graeber TG, Robins H, Ribas A. CTLA4 blockade broadens the peripheral T-cell receptor repertoire Clinical Cancer Research. 20: 2424-2432. PMID 24583799 DOI: 10.1158/1078-0432.Ccr-13-2648  0.096
2019 Garcia-Diaz A, Shin DS, Moreno BH, Saco J, Escuin-Ordinas H, Rodriguez GA, Zaretsky JM, Sun L, Hugo W, Wang X, Parisi G, Saus CP, Torrejon DY, Graeber TG, Comin-Anduix B, et al. Interferon Receptor Signaling Pathways Regulating PD-L1 and PD-L2 Expression. Cell Reports. 29: 3766. PMID 31825850 DOI: 10.1016/j.celrep.2019.11.113  0.093
2015 Shin D, Garcia-Diaz A, Zaretsky J, Escuin-Ordinas H, Hu-Lieskovan S, Palaskas NJ, Hugo W, Komenan MS, Chmielowski B, Cherry G, Berent-Maoz B, Graeber TG, Lo R, Comin-Anduix B, Ribas A. Innate resistance of PD-1 blockade through loss of function mutations in JAK resulting in inability to express PD-L1 upon interferon exposure Journal For Immunotherapy of Cancer. 3. DOI: 10.1186/2051-1426-3-S2-P311  0.086
2016 Chen Z, Shojaee S, Buchner M, Geng H, Lee JW, Klemm L, Titz B, Graeber TG, Park E, Tan YX, Satterthwaite A, Paietta E, Hunger SP, Willman CL, Melnick A, et al. Corrigendum: Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia. Nature. PMID 26958840 DOI: 10.1038/Nature16997  0.069
1996 Derevianko A, Graeber T, Simms H. REACTIVE OXYGEN INTERMEDIATES (ROI) - A NOVEL ROLE AS SECOND MESSENGERS IN CYTOKINE STIMULATED PMN. Shock. 5: 49. DOI: 10.1097/00024382-199606002-00157  0.065
2020 Falk A, Graeber T. Delayed negative effects of prosocial spending on happiness. Proceedings of the National Academy of Sciences of the United States of America. PMID 32152104 DOI: 10.1073/Pnas.1914324117  0.063
1998 Derevianko A, DʼAmico R, Graeber T, Simms HH. PMN-DERIVED ROI AUTOREGULATE TNF-α SIGNAL TRANSDUCTION. Shock. 9: 65. DOI: 10.1097/00024382-199806001-00221  0.061
2021 Xiang Y, Graeber T, Enke B, Gershman SJ. Confidence and central tendency in perceptual judgment. Attention, Perception & Psychophysics. PMID 33890239 DOI: 10.3758/s13414-021-02300-6  0.059
1997 Knowles R, Keeping H, Graeber T, Nguyen K, Garner C, D'Amico R, Simms HH. Cytokine control of PMN phagocytosis: regulatory effects of hypoxemia and hypoxemia-reoxygenation. The American Journal of Physiology. 272: C1352-64. PMID 9142862 DOI: 10.1152/AJPCELL.1997.272.4.C1352  0.056
2003 Strong M, Graeber TG, Beeby M, Pellegrini M, Thompson MJ, Yeates TO, Eisenberg D. Visualization and intepretation of protein networks in Mycobacterium tuberculosis based on hierarchical clustering of genome-wide functional linkage maps Nucleic Acids Research. 31: 7099-7109. DOI: 10.1093/nar/gkg924  0.048
2021 Fetzer T, Graeber T. Measuring the scientific effectiveness of contact tracing: Evidence from a natural experiment. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34385318 DOI: 10.1073/pnas.2100814118  0.046
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