Brett R. Blackman - Publications

Affiliations: 
University of Virginia, Charlottesville, VA 
Area:
Biomedical Engineering

31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Collado MS, Cole BK, Figler RA, Lawson M, Manka D, Simmers MB, Hoang S, Serrano F, Blackman BR, Sinha S, Wamhoff BR. Exposure of Induced Pluripotent Stem Cell-Derived Vascular Endothelial and Smooth Muscle Cells in Coculture to Hemodynamics Induces Primary Vascular Cell-Like Phenotypes. Stem Cells Translational Medicine. PMID 28628273 DOI: 10.1002/sctm.17-0004  0.56
2016 Feaver RE, Cole BK, Lawson MJ, Hoang SA, Marukian S, Blackman BR, Figler RA, Sanyal AJ, Wamhoff BR, Dash A. Development of an in vitro human liver system for interrogating nonalcoholic steatohepatitis. Jci Insight. 1: e90954. PMID 27942596 DOI: 10.1172/jci.insight.90954  0.72
2016 Dash A, Figler RA, Blackman BR, Marukian S, Collado MS, Lawson MJ, Hoang SA, Mackey AJ, Manka D, Cole BK, Feaver RE, Sanyal AJ, Wamhoff BR. Pharmacotoxicology of clinically-relevant concentrations of obeticholic acid in an organotypic human hepatocyte system. Toxicology in Vitro : An International Journal Published in Association With Bibra. PMID 27939613 DOI: 10.1016/j.tiv.2016.11.014  0.72
2016 Simmers MB, Cole BK, Ogletree ML, Chen Z, Xu Y, Kong LJ, Mackman N, Blackman BR, Wamhoff BR. Hemodynamics associated with atrial fibrillation directly alters thrombotic potential of endothelial cells. Thrombosis Research. 143: 34-39. PMID 27179130 DOI: 10.1016/j.thromres.2016.04.022  0.72
2015 Terelius Y, Figler RA, Marukian S, Collado MS, Lawson MJ, Mackey AJ, Manka D, Qualls CW, Blackman BR, Wamhoff BR, Dash A. Transcriptional Profiling Suggests That Nevirapine and Ritonavir Cause Drug Induced Liver Injury Through Distinct Mechanisms in Primary Human Hepatocytes. Chemico-Biological Interactions. PMID 26626330 DOI: 10.1016/j.cbi.2015.11.023  0.72
2015 Heuslein JL, Meisner JK, Li X, Song J, Vincentelli H, Leiphart RJ, Ames EG, Price RJ. Mechanisms of Amplified Arteriogenesis in Collateral Artery Segments Exposed to Flow Direction Reversal. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 26338297 DOI: 10.1161/ATVBAHA.115.305775  0.72
2015 Cole BK, Simmers MB, Feaver R, Qualls CW, Collado MS, Berzin E, Figler RA, Pryor AW, Lawson M, Mackey A, Manka D, Wamhoff BR, Turk JR, Blackman BR. An In Vitro Cynomolgus Vascular Surrogate System for Preclinical Drug Assessment and Human Translation. Arteriosclerosis, Thrombosis, and Vascular Biology. 35: 2185-95. PMID 26293464 DOI: 10.1161/ATVBAHA.115.306245  0.72
2013 Dash A, Simmers MB, Deering TG, Berry DJ, Feaver RE, Hastings NE, Pruett TL, LeCluyse EL, Blackman BR, Wamhoff BR. Hemodynamic flow improves rat hepatocyte morphology, function, and metabolic activity in vitro. American Journal of Physiology. Cell Physiology. 304: C1053-63. PMID 23485712 DOI: 10.1152/ajpcell.00331.2012  0.72
2013 Feaver RE, Gelfand BD, Blackman BR. Human haemodynamic frequency harmonics regulate the inflammatory phenotype of vascular endothelial cells. Nature Communications. 4: 1525. PMID 23443553 DOI: 10.1038/ncomms2530  0.72
2012 Zhou G, Hamik A, Nayak L, Tian H, Shi H, Lu Y, Sharma N, Liao X, Hale A, Boerboom L, Feaver RE, Gao H, Desai A, Schmaier A, Gerson SL, ... ... Blackman BR, et al. Endothelial Kruppel-like factor 4 protects against atherothrombosis in mice. The Journal of Clinical Investigation. 122: 4727-31. PMID 23160196 DOI: 10.1172/JCI66056  0.72
2012 Dash A, Blackman BR, Wamhoff BR. Organotypic systems in drug metabolism and toxicity: challenges and opportunities. Expert Opinion On Drug Metabolism & Toxicology. 8: 999-1014. PMID 22632603 DOI: 10.1517/17425255.2012.693161  0.56
2012 Tilghman RW, Blais EM, Cowan CR, Sherman NE, Grigera PR, Jeffery ED, Fox JW, Blackman BR, Tschumperlin DJ, Papin JA, Parsons JT. Matrix rigidity regulates cancer cell growth by modulating cellular metabolism and protein synthesis. Plos One. 7: e37231. PMID 22623999 DOI: 10.1371/Journal.Pone.0037231  0.72
2011 Janiczek RL, Blackman BR, Roy RJ, Meyer CH, Acton ST, Epstein FH. Three-dimensional phase contrast angiography of the mouse aortic arch using spiral MRI. Magnetic Resonance in Medicine. 66: 1382-90. PMID 21656547 DOI: 10.1002/Mrm.22937  0.72
2011 Gelfand BD, Meller J, Pryor AW, Kahn M, Bortz PD, Wamhoff BR, Blackman BR. Hemodynamic activation of beta-catenin and T-cell-specific transcription factor signaling in vascular endothelium regulates fibronectin expression. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 1625-33. PMID 21527747 DOI: 10.1161/ATVBAHA.111.227827  0.72
2010 Tilghman RW, Cowan CR, Mih JD, Koryakina Y, Gioeli D, Slack-Davis JK, Blackman BR, Tschumperlin DJ, Parsons JT. Matrix rigidity regulates cancer cell growth and cellular phenotype Plos One. 5. PMID 20886123 DOI: 10.1371/Journal.Pone.0012905  0.72
2010 Feaver RE, Gelfand BD, Wang C, Schwartz MA, Blackman BR. Atheroprone hemodynamics regulate fibronectin deposition to create positive feedback that sustains endothelial inflammation. Circulation Research. 106: 1703-11. PMID 20378855 DOI: 10.1161/Circresaha.109.216283  0.72
2010 Orr AW, Hastings NE, Blackman BR, Wamhoff BR. Complex regulation and function of the inflammatory smooth muscle cell phenotype in atherosclerosis. Journal of Vascular Research. 47: 168-80. PMID 19851078 DOI: 10.1159/000250095  0.72
2009 Hastings NE, Feaver RE, Lee MY, Wamhoff BR, Blackman BR. Human IL-8 regulates smooth muscle cell VCAM-1 expression in response to endothelial cells exposed to atheroprone flow. Arteriosclerosis, Thrombosis, and Vascular Biology. 29: 725-31. PMID 19229069 DOI: 10.1161/ATVBAHA.109.184382  0.72
2009 Jin L, Hastings NE, Blackman BR, Somlyo AV. Mechanical properties of the extracellular matrix alter expression of smooth muscle protein LPP and its partner palladin; relationship to early atherosclerosis and vascular injury. Journal of Muscle Research and Cell Motility. 30: 41-55. PMID 19205907 DOI: 10.1007/s10974-009-9173-1  0.72
2009 Thomas JA, Deaton RA, Hastings NE, Shang Y, Moehle CW, Eriksson U, Topouzis S, Wamhoff BR, Blackman BR, Owens GK. PDGF-DD, a novel mediator of smooth muscle cell phenotypic modulation, is upregulated in endothelial cells exposed to atherosclerosis-prone flow patterns. American Journal of Physiology. Heart and Circulatory Physiology. 296: H442-52. PMID 19028801 DOI: 10.1152/ajpheart.00165.2008  0.72
2008 Anderson CR, Hastings NE, Blackman BR, Price RJ. Capillary sprout endothelial cells exhibit a CD36 low phenotype: regulation by shear stress and vascular endothelial growth factor-induced mechanism for attenuating anti-proliferative thrombospondin-1 signaling. The American Journal of Pathology. 173: 1220-8. PMID 18772338 DOI: 10.2353/ajpath.2008.071194  0.72
2008 Harry BL, Sanders JM, Feaver RE, Lansey M, Deem TL, Zarbock A, Bruce AC, Pryor AW, Gelfand BD, Blackman BR, Schwartz MA, Ley K. Endothelial cell PECAM-1 promotes atherosclerotic lesions in areas of disturbed flow in ApoE-deficient mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 2003-8. PMID 18688018 DOI: 10.1161/Atvbaha.108.164707  0.72
2008 Orr AW, Hahn C, Blackman BR, Schwartz MA. p21-activated kinase signaling regulates oxidant-dependent NF-kappa B activation by flow. Circulation Research. 103: 671-9. PMID 18669917 DOI: 10.1161/Circresaha.108.182097  0.72
2008 Feaver RE, Hastings NE, Pryor A, Blackman BR. GRP78 upregulation by atheroprone shear stress via p38-, alpha2beta1-dependent mechanism in endothelial cells. Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 1534-41. PMID 18556570 DOI: 10.1161/ATVBAHA.108.167999  0.72
2007 Hastings NE, Simmers MB, McDonald OG, Wamhoff BR, Blackman BR. Atherosclerosis-prone hemodynamics differentially regulates endothelial and smooth muscle cell phenotypes and promotes pro-inflammatory priming. American Journal of Physiology. Cell Physiology. 293: C1824-33. PMID 17913848 DOI: 10.1152/ajpcell.00385.2007  0.72
2007 Simmers MB, Pryor AW, Blackman BR. Arterial shear stress regulates endothelial cell-directed migration, polarity, and morphology in confluent monolayers. American Journal of Physiology. Heart and Circulatory Physiology. 293: H1937-46. PMID 17586613 DOI: 10.1152/ajpheart.00534.2007  0.72
2007 Orr AW, Stockton R, Simmers MB, Sanders JM, Sarembock IJ, Blackman BR, Schwartz MA. Matrix-specific p21-activated kinase activation regulates vascular permeability in atherogenesis. The Journal of Cell Biology. 176: 719-27. PMID 17312022 DOI: 10.1083/Jcb.200609008  0.72
2006 Gelfand BD, Epstein FH, Blackman BR. Spatial and spectral heterogeneity of time-varying shear stress profiles in the carotid bifurcation by phase-contrast MRI. Journal of Magnetic Resonance Imaging : Jmri. 24: 1386-92. PMID 17083089 DOI: 10.1002/jmri.20765  0.64
2006 Wieghaus KA, Capitosti SM, Anderson CR, Price RJ, Blackman BR, Brown ML, Botchwey EA. Small molecule inducers of angiogenesis for tissue engineering. Tissue Engineering. 12: 1903-13. PMID 16889520 DOI: 10.1089/Ten.2006.12.1903  0.72
2006 Orr AW, Helmke BP, Blackman BR, Schwartz MA. Mechanisms of mechanotransduction. Developmental Cell. 10: 11-20. PMID 16399074 DOI: 10.1016/J.Devcel.2005.12.006  0.72
2001 García-Cardeña G, Comander J, Anderson KR, Blackman BR, Gimbrone MA. Biomechanical activation of vascular endothelium as a determinant of its functional phenotype Proceedings of the National Academy of Sciences of the United States of America. 98: 4478-4485. PMID 11296290 DOI: 10.1073/pnas.071052598  0.72
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