| Year |
Citation |
Score |
| 2023 |
Xie L, Bowman ME, Louie GV, Zhang C, Ardejani MS, Huang X, Chu Q, Donaldson CJ, Vaughan JM, Shan H, Powers ET, Kelly JW, Lyumkis D, Noel JP, Saghatelian A. Biochemistry and Protein Interactions of the CYREN Microprotein. Biochemistry. PMID 37813856 DOI: 10.1021/acs.biochem.3c00397 |
0.779 |
|
| 2023 |
Lazear MR, Remsberg JR, Jaeger MG, Rothamel K, Her HL, DeMeester KE, Njomen E, Hogg SJ, Rahman J, Whitby LR, Won SJ, Schafroth MA, Ogasawara D, Yokoyama M, Lindsey GL, ... ... Saghatelian A, et al. Proteomic discovery of chemical probes that perturb protein complexes in human cells. Molecular Cell. PMID 37084731 DOI: 10.1016/j.molcel.2023.03.026 |
0.757 |
|
| 2023 |
Morgado-Palacin L, Brown JA, Martinez TF, Garcia-Pedrero JM, Forouhar F, Quinn SA, Reglero C, Vaughan J, Heydary YH, Donaldson C, Rodriguez-Perales S, Allonca E, Granda-Diaz R, Fernandez AF, Fraga MF, ... ... Saghatelian A, et al. The TINCR ubiquitin-like microprotein is a tumor suppressor in squamous cell carcinoma. Nature Communications. 14: 1328. PMID 36899004 DOI: 10.1038/s41467-023-36713-8 |
0.626 |
|
| 2023 |
Martinez TF, Lyons-Abbott S, Bookout AL, De Souza EV, Donaldson C, Vaughan JM, Lau C, Abramov A, Baquero AF, Baquero K, Friedrich D, Huard J, Davis R, Kim B, Koch T, ... ... Saghatelian A, et al. Profiling mouse brown and white adipocytes to identify metabolically relevant small ORFs and functional microproteins. Cell Metabolism. 35: 166-183.e11. PMID 36599300 DOI: 10.1016/j.cmet.2022.12.004 |
0.668 |
|
| 2022 |
Mudge JM, Ruiz-Orera J, Prensner JR, Brunet MA, Calvet F, Jungreis I, Gonzalez JM, Magrane M, Martinez TF, Schulz JF, Yang YT, Albà MM, Aspden JL, Baranov PV, Bazzini AA, ... ... Saghatelian A, et al. Standardized annotation of translated open reading frames. Nature Biotechnology. PMID 35831657 DOI: 10.1038/s41587-022-01369-0 |
0.601 |
|
| 2021 |
Koh M, Ahmad I, Ko Y, Zhang Y, Martinez TF, Diedrich JK, Chu Q, Moresco JJ, Erb MA, Saghatelian A, Schultz PG, Bollong MJ. A short ORF-encoded transcriptional regulator. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33468658 DOI: 10.1073/pnas.2021943118 |
0.684 |
|
| 2020 |
Becuwe M, Bond LM, Pinto AFM, Boland S, Mejhert N, Elliott SD, Cicconet M, Graham MM, Liu XN, Ilkayeva O, Saghatelian A, Walther TC, Farese RV. FIT2 is an acyl-coenzyme A diphosphatase crucial for endoplasmic reticulum homeostasis. The Journal of Cell Biology. 219. PMID 32915949 DOI: 10.1083/Jcb.202006111 |
0.322 |
|
| 2020 |
Muthusamy T, Cordes T, Handzlik MK, You L, Lim EW, Gengatharan J, Pinto AFM, Badur MG, Kolar MJ, Wallace M, Saghatelian A, Metallo CM. Serine restriction alters sphingolipid diversity to constrain tumour growth. Nature. PMID 32788725 DOI: 10.1038/S41586-020-2609-X |
0.331 |
|
| 2020 |
Chen PB, Black AS, Sobel AL, Zhao Y, Mukherjee P, Molparia B, Moore NE, Aleman Muench GR, Wu J, Chen W, Pinto AFM, Maryanoff BE, Saghatelian A, Soroosh P, Torkamani A, et al. Directed remodeling of the mouse gut microbiome inhibits the development of atherosclerosis. Nature Biotechnology. PMID 32541956 DOI: 10.1038/S41587-020-0549-5 |
0.774 |
|
| 2020 |
Martinez TF, Vaughan J, Saghatelian A. Insights into GLP-1 Receptor Activation with a Nonpeptide Agonist. Biochemistry. PMID 32297516 DOI: 10.1021/Acs.Biochem.0C00180 |
0.628 |
|
| 2020 |
Erikci Ertunc M, Kok BP, Parsons WH, Wang JG, Tan D, Donaldson CJ, Pinto AFM, Vaughan JM, Ngo N, Lum KM, Henry CL, Coppola AR, Niphakis MJ, Cravatt BF, Saez E, ... Saghatelian A, et al. AIG1 and ADTRP are endogenous hydrolases of fatty acid esters of hydroxy fatty acids (FAHFAs) in mice. The Journal of Biological Chemistry. PMID 32152231 DOI: 10.1074/Jbc.Ra119.012145 |
0.533 |
|
| 2020 |
Ertunc ME, Kok BP, Parsons WH, Wang JG, Tan D, Donaldson CJ, Pinto AM, Vaughan JM, Ngo N, Lum KM, Henry CL, Coppola AR, Niphakis MJ, Cravatt BF, Saez E, ... Saghatelian A, et al. Role of AIG1 and ADTRP in Endogenous FAHFA Regulation The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.04337 |
0.456 |
|
| 2020 |
Martinez TF, Chu Q, Donaldson C, Tan D, Shokhirev MN, Saghatelian A. Accurate Annotation of Protein‐coding Small Open Reading Frames in the Human Genome The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.03051 |
0.639 |
|
| 2019 |
Martinez TF, Chu Q, Donaldson C, Tan D, Shokhirev MN, Saghatelian A. Accurate annotation of human protein-coding small open reading frames. Nature Chemical Biology. PMID 31819274 DOI: 10.1038/S41589-019-0425-0 |
0.697 |
|
| 2019 |
Chu Q, Martinez TF, Novak SW, Donaldson CJ, Tan D, Vaughan JM, Chang T, Diedrich JK, Andrade L, Kim A, Zhang T, Manor U, Saghatelian A. Regulation of the ER stress response by a mitochondrial microprotein. Nature Communications. 10: 4883. PMID 31653868 DOI: 10.1096/Fasebj.2020.34.S1.04094 |
0.665 |
|
| 2019 |
Tan D, Ertunc ME, Konduri S, Zhang J, Pinto AM, Chu Q, Kahn BB, Siegel D, Saghatelian A. Discovery of FAHFA-containing Triacylglycerols and Their Metabolic Regulation. Journal of the American Chemical Society. PMID 31056915 DOI: 10.1021/Jacs.9B00045 |
0.368 |
|
| 2019 |
Wang H, Chang T, Konduri S, Huang J, Saghatelian A, Siegel D. Synthesis of chemically edited derivatives of the endogenous regulator of inflammation 9-PAHSA. The Journal of Antibiotics. PMID 30988370 DOI: 10.1038/S41429-019-0180-1 |
0.311 |
|
| 2019 |
Choi SH, Martinez TF, Kim S, Donaldson C, Shokhirev MN, Saghatelian A, Jones KA. CDK12 phosphorylates 4E-BP1 to enable mTORC1-dependent translation and mitotic genome stability. Genes & Development. PMID 30819820 DOI: 10.1101/Gad.322339.118 |
0.656 |
|
| 2019 |
Garcia D, Hellberg K, Chaix A, Wallace M, Herzig S, Badur MG, Lin T, Shokhirev MN, Pinto AFM, Ross DS, Saghatelian A, Panda S, Dow LE, Metallo CM, Shaw RJ. Genetic Liver-Specific AMPK Activation Protects against Diet-Induced Obesity and NAFLD. Cell Reports. 26: 192-208.e6. PMID 30605676 DOI: 10.1016/J.Celrep.2018.12.036 |
0.305 |
|
| 2018 |
Rathore A, Martinez TF, Chu Q, Saghatelian A. Small, but mighty? Searching for human microproteins and their potential for understanding health and disease. Expert Review of Proteomics. PMID 30415582 DOI: 10.1080/14789450.2018.1547194 |
0.637 |
|
| 2018 |
Rathore A, Chu Q, Tan D, Martinez TF, Donaldson CJ, Diedrich JK, Yates JR, Saghatelian A. MIEF1 Microprotein Regulates Mitochondrial Translation. Biochemistry. PMID 30215512 DOI: 10.1021/Acs.Biochem.8B00726 |
0.674 |
|
| 2018 |
Zarrinpar A, Chaix A, Xu ZZ, Chang MW, Marotz CA, Saghatelian A, Knight R, Panda S. Antibiotic-induced microbiome depletion alters metabolic homeostasis by affecting gut signaling and colonic metabolism. Nature Communications. 9: 2872. PMID 30030441 DOI: 10.1038/S41467-018-05336-9 |
0.327 |
|
| 2018 |
Ma J, Saghatelian A, Shokhirev MN. The influence of transcript assembly on the proteogenomics discovery of microproteins. Plos One. 13: e0194518. PMID 29584760 DOI: 10.1371/Journal.Pone.0194518 |
0.371 |
|
| 2018 |
Kolar MJ, Nelson AT, Chang T, Ertunc ME, Christy MP, Ohlsson L, Härröd M, Kahn BB, Siegel D, Saghatelian A. Faster Protocol for Endogenous Fatty Acid Esters of Hydroxy Fatty Acid (FAHFA) Measurements. Analytical Chemistry. PMID 29578702 DOI: 10.1021/Acs.Analchem.8B00503 |
0.317 |
|
| 2018 |
Aebersold R, Agar JN, Amster IJ, Baker MS, Bertozzi CR, Boja ES, Costello CE, Cravatt BF, Fenselau C, Garcia BA, Ge Y, Gunawardena J, Hendrickson RC, Hergenrother PJ, Huber CG, ... ... Saghatelian A, et al. How many human proteoforms are there? Nature Chemical Biology. 14: 206-214. PMID 29443976 DOI: 10.1038/Nchembio.2576 |
0.753 |
|
| 2018 |
Sulli G, Rommel A, Wang X, Kolar MJ, Puca F, Saghatelian A, Plikus MV, Verma IM, Panda S. Pharmacological activation of REV-ERBs is lethal in cancer and oncogene-induced senescence. Nature. PMID 29320480 DOI: 10.1038/Nature25170 |
0.319 |
|
| 2018 |
Sulli G, Rommel A, Wang X, Kolar MJ, Puca F, Saghatelian A, Plikus MV, Verma IM, Panda S. Abstract 5464: Pharmacologic activation of REV-ERBs is lethal in cancer and oncogene-induced senescence Cancer Research. 78: 5464-5464. DOI: 10.1158/1538-7445.Am2018-5464 |
0.308 |
|
| 2017 |
Chu Q, Rathore A, Diedrich JK, Donaldson CJ, Yates JR, Saghatelian A. Identification of Microprotein-Protein Interactions via APEX Tagging. Biochemistry. PMID 28589727 DOI: 10.1021/Acs.Biochem.7B00265 |
0.377 |
|
| 2017 |
Nelson AT, Kolar MJ, Chu Q, Syed I, Kahn BB, Saghatelian A, Siegel D. Stereochemistry of Endogenous Palmitic Acid Ester of 9-Hydroxystearic Acid and Relevance of Absolute Configuration to Regulation. Journal of the American Chemical Society. PMID 28350171 DOI: 10.1021/Jacs.7B01269 |
0.355 |
|
| 2017 |
Grünberg JR, Hoffmann JM, Hedjazifar S, Nerstedt A, Jenndahl L, Elvin J, Castellot J, Wei L, Movérare-Skrtic S, Ohlsson C, Holm LM, Bäckhed F, Syed I, Bosch F, Saghatelian A, et al. Overexpressing the novel autocrine/endocrine adipokine WISP2 induces hyperplasia of the heart, white and brown adipose tissues and prevents insulin resistance. Scientific Reports. 7: 43515. PMID 28240264 DOI: 10.1038/Srep43515 |
0.318 |
|
| 2016 |
Howell JJ, Hellberg K, Turner M, Talbott G, Kolar MJ, Ross DS, Hoxhaj G, Saghatelian A, Shaw RJ, Manning BD. Metformin Inhibits Hepatic mTORC1 Signaling via Dose-Dependent Mechanisms Involving AMPK and the TSC Complex. Cell Metabolism. PMID 28089566 DOI: 10.1016/J.Cmet.2016.12.009 |
0.317 |
|
| 2016 |
Matsumoto A, Pasut A, Matsumoto M, Yamashita R, Fung J, Monteleone E, Saghatelian A, Nakayama KI, Clohessy JG, Pandolfi PP. mTORC1 and muscle regeneration are regulated by the LINC00961-encoded SPAR polypeptide. Nature. PMID 28024296 DOI: 10.1038/Nature21034 |
0.357 |
|
| 2016 |
D'Lima NG, Ma J, Winkler L, Chu Q, Loh KH, Corpuz EO, Budnik BA, Lykke-Andersen J, Saghatelian A, Slavoff SA. A human microprotein that interacts with the mRNA decapping complex. Nature Chemical Biology. PMID 27918561 DOI: 10.1038/Nchembio.2249 |
0.766 |
|
| 2016 |
Saghatelian A, Cravatt B. Glucagon and Thyroid Hormone: A Championship Team. Cell. 167: 604-605. PMID 27768884 DOI: 10.1016/J.Cell.2016.10.008 |
0.302 |
|
| 2016 |
Kolar MJ, Kamat SS, Parsons WH, Homan EA, Maher T, Peroni OD, Syed I, Fjeld K, Molven A, Kahn BB, Cravatt BF, Saghatelian A. Branched Fatty Acid Esters of Hydroxy Fatty Acids Are Preferred Substrates of the MODY8 Protein Carboxyl Ester Lipase. Biochemistry. PMID 27509211 DOI: 10.1021/Acs.Biochem.6B00565 |
0.774 |
|
| 2016 |
Pirhaji L, Milani P, Leidl M, Curran T, Avila-Pacheco J, Clish CB, White FM, Saghatelian A, Fraenkel E. Revealing disease-associated pathways by network integration of untargeted metabolomics. Nature Methods. PMID 27479327 DOI: 10.1038/Nmeth.3940 |
0.341 |
|
| 2016 |
Moraes-Vieira PM, Saghatelian A, Kahn BB. GLUT4 Expression in Adipocytes Regulates De Novo Lipogenesis and Levels of a Novel Class of Lipids With Antidiabetic and Anti-inflammatory Effects. Diabetes. PMID 27288004 DOI: 10.2337/Db16-0221 |
0.346 |
|
| 2016 |
Parsons WH, Kolar MJ, Kamat SS, Iii AB, Hulce JJ, Saez E, Kahn BB, Saghatelian A, Cravatt BF. AIG1 and ADTRP are atypical integral membrane hydrolases that degrade bioactive FAHFAs. Nature Chemical Biology. PMID 27018888 DOI: 10.1038/Nchembio.2051 |
0.693 |
|
| 2016 |
Ma J, Diedrich JK, Jungreis I, Donaldson C, Vaughan J, Kellis M, Yates JR, Saghatelian A. Improved Identification and Analysis of Small Open Reading Frame Encoded Polypeptides. Analytical Chemistry. PMID 27010111 DOI: 10.1021/Acs.Analchem.6B00191 |
0.348 |
|
| 2016 |
Zhang T, Chen S, Syed I, Ståhlman M, Kolar MJ, Homan EA, Chu Q, Smith U, Borén J, Kahn BB, Saghatelian A. A LC-MS-based workflow for measurement of branched fatty acid esters of hydroxy fatty acids. Nature Protocols. 11: 747-763. PMID 26985573 DOI: 10.1038/Nprot.2016.040 |
0.745 |
|
| 2016 |
Wei W, Schwaid AG, Wang X, Wang X, Chen S, Chu Q, Saghatelian A, Wan Y. Ligand Activation of ERRα by Cholesterol Mediates Statin and Bisphosphonate Effects. Cell Metabolism. PMID 26777690 DOI: 10.1016/J.Cmet.2015.12.010 |
0.302 |
|
| 2015 |
Saghatelian A, Nomura DK, Weerapena E. Editorial overview: Omics: The maturation of chemical biology. Current Opinion in Chemical Biology. PMID 26739665 DOI: 10.1016/J.Cbpa.2015.12.005 |
0.562 |
|
| 2015 |
Saghatelian A, Couso JP. Discovery and characterization of smORF-encoded bioactive polypeptides. Nature Chemical Biology. 11: 909-16. PMID 26575237 DOI: 10.1038/Nchembio.1964 |
0.373 |
|
| 2015 |
Denli AM, Narvaiza I, Kerman BE, Pena M, Benner C, Marchetto MC, Diedrich JK, Aslanian A, Ma J, Moresco JJ, Moore L, Hunter T, Saghatelian A, Gage FH. Primate-Specific ORF0 Contributes to Retrotransposon-Mediated Diversity. Cell. 163: 583-93. PMID 26496605 DOI: 10.1016/J.Cell.2015.09.025 |
0.346 |
|
| 2015 |
Zhang T, Barclay L, Walensky LD, Saghatelian A. Regulation of mitochondrial ceramide distribution by members of the BCL-2 family. Journal of Lipid Research. PMID 26059977 DOI: 10.1194/Jlr.M058750 |
0.322 |
|
| 2015 |
Zamboni N, Saghatelian A, Patti GJ. Defining the Metabolome: Size, Flux, and Regulation. Molecular Cell. 58: 699-706. PMID 26000853 DOI: 10.1016/J.Molcel.2015.04.021 |
0.316 |
|
| 2015 |
Chu Q, Ma J, Saghatelian A. Identification and characterization of sORF-encoded polypeptides. Critical Reviews in Biochemistry and Molecular Biology. 50: 134-41. PMID 25857697 DOI: 10.3109/10409238.2015.1016215 |
0.366 |
|
| 2015 |
Zhang T, Walensky LD, Saghatelian A. A Nonapoptotic Role for BAX and BAK in Eicosanoid Metabolism. Acs Chemical Biology. 10: 1398-403. PMID 25815636 DOI: 10.1021/Acschembio.5B00168 |
0.333 |
|
| 2014 |
Prothiwa M, Syed I, Huising MO, van der Meulen T, Donaldson CJ, Trauger SA, Kahn BB, Saghatelian A. Data-driven synthesis of proteolysis-resistant peptide hormones. Journal of the American Chemical Society. 136: 17710-3. PMID 25496053 DOI: 10.1021/Ja5065735 |
0.344 |
|
| 2014 |
Yore MM, Syed I, Moraes-Vieira PM, Zhang T, Herman MA, Homan EA, Patel RT, Lee J, Chen S, Peroni OD, Dhaneshwar AS, Hammarstedt A, Smith U, McGraw TE, Saghatelian A, et al. Discovery of a class of endogenous mammalian lipids with anti-diabetic and anti-inflammatory effects. Cell. 159: 318-32. PMID 25303528 DOI: 10.1016/J.Cell.2014.09.035 |
0.739 |
|
| 2014 |
Johnson LM, Barrick S, Hager MV, McFedries A, Homan EA, Rabaglia ME, Keller MP, Attie AD, Saghatelian A, Bisello A, Gellman SH. A potent α/β-peptide analogue of GLP-1 with prolonged action in vivo. Journal of the American Chemical Society. 136: 12848-51. PMID 25191938 DOI: 10.1021/Ja507168T |
0.753 |
|
| 2014 |
Slavoff SA, Heo J, Budnik BA, Hanakahi LA, Saghatelian A. A human short open reading frame (sORF)-encoded polypeptide that stimulates DNA end joining. The Journal of Biological Chemistry. 289: 10950-7. PMID 24610814 DOI: 10.1074/Jbc.C113.533968 |
0.694 |
|
| 2014 |
Lone AM, Leidl M, McFedries AK, Horner JW, Creemers J, Saghatelian A. Deletion of PREPl causes growth impairment and hypotonia in mice. Plos One. 9: e89160. PMID 24586561 DOI: 10.1371/Journal.Pone.0089160 |
0.748 |
|
| 2014 |
Ma J, Ward CC, Jungreis I, Slavoff SA, Schwaid AG, Neveu J, Budnik BA, Kellis M, Saghatelian A. Discovery of human sORF-encoded polypeptides (SEPs) in cell lines and tissue. Journal of Proteome Research. 13: 1757-65. PMID 24490786 DOI: 10.1021/Pr401280W |
0.712 |
|
| 2013 |
Liu S, Brown JD, Stanya KJ, Homan E, Leidl M, Inouye K, Bhargava P, Gangl MR, Dai L, Hatano B, Hotamisligil GS, Saghatelian A, Plutzky J, Lee CH. A diurnal serum lipid integrates hepatic lipogenesis and peripheral fatty acid use. Nature. 502: 550-4. PMID 24153306 DOI: 10.1038/Nature12710 |
0.752 |
|
| 2013 |
Schwaid AG, Shannon DA, Ma J, Slavoff SA, Levin JZ, Weerapana E, Saghatelian A. Chemoproteomic discovery of cysteine-containing human short open reading frames. Journal of the American Chemical Society. 135: 16750-3. PMID 24152191 DOI: 10.1021/Ja406606J |
0.78 |
|
| 2013 |
Kim YG, Lone AM, Saghatelian A. Analysis of the proteolysis of bioactive peptides using a peptidomics approach. Nature Protocols. 8: 1730-42. PMID 23949379 DOI: 10.1038/Nprot.2013.104 |
0.767 |
|
| 2013 |
Mitchell AJ, Lone AM, Tinoco AD, Saghatelian A. Proteolysis controls endogenous substance P levels. Plos One. 8: e68638. PMID 23894327 DOI: 10.1371/Journal.Pone.0068638 |
0.757 |
|
| 2013 |
McFedries A, Schwaid A, Saghatelian A. Methods for the elucidation of protein-small molecule interactions. Chemistry & Biology. 20: 667-73. PMID 23706633 DOI: 10.1016/J.Chembiol.2013.04.008 |
0.364 |
|
| 2013 |
Miraldi ER, Sharfi H, Friedline RH, Johnson H, Zhang T, Lau KS, Ko HJ, Curran TG, Haigis KM, Yaffe MB, Bonneau R, Lauffenburger DA, Kahn BB, Kim JK, Neel BG, ... Saghatelian A, et al. Molecular network analysis of phosphotyrosine and lipid metabolism in hepatic PTP1b deletion mice. Integrative Biology : Quantitative Biosciences From Nano to Macro. 5: 940-63. PMID 23685806 DOI: 10.1039/C3Ib40013A |
0.337 |
|
| 2013 |
Zhang T, Saghatelian A. Emerging roles of lipids in BCL-2 family-regulated apoptosis. Biochimica Et Biophysica Acta. 1831: 1542-54. PMID 23524027 DOI: 10.1016/J.Bbalip.2013.03.001 |
0.319 |
|
| 2013 |
Lone AM, Kim YG, Saghatelian A. Peptidomics methods for the identification of peptidase-substrate interactions. Current Opinion in Chemical Biology. 17: 83-9. PMID 23332665 DOI: 10.1016/J.Cbpa.2012.10.038 |
0.768 |
|
| 2013 |
Cezairliyan B, Vinayavekhin N, Grenfell-Lee D, Yuen GJ, Saghatelian A, Ausubel FM. Identification of Pseudomonas aeruginosa phenazines that kill Caenorhabditis elegans. Plos Pathogens. 9: e1003101. PMID 23300454 DOI: 10.1371/Journal.Ppat.1003101 |
0.753 |
|
| 2013 |
Slavoff SA, Mitchell AJ, Schwaid AG, Cabili MN, Ma J, Levin JZ, Karger AD, Budnik BA, Rinn JL, Saghatelian A. Peptidomic discovery of short open reading frame-encoded peptides in human cells. Nature Chemical Biology. 9: 59-64. PMID 23160002 DOI: 10.1038/Nchembio.1120 |
0.716 |
|
| 2012 |
Slavoff SA, Saghatelian A. Discovering ligand-receptor interactions. Nature Biotechnology. 30: 959-61. PMID 23051814 DOI: 10.1038/Nbt.2373 |
0.661 |
|
| 2012 |
Kim YG, Lone AM, Nolte WM, Saghatelian A. Peptidomics approach to elucidate the proteolytic regulation of bioactive peptides. Proceedings of the National Academy of Sciences of the United States of America. 109: 8523-7. PMID 22586115 DOI: 10.1073/Pnas.1203195109 |
0.793 |
|
| 2012 |
Tinoco AD, Thomas HR, Incarvito CD, Saghatelian A, Valentine AM. Cytotoxicity of a Ti(IV) compound is independent of serum proteins. Proceedings of the National Academy of Sciences of the United States of America. 109: 5016-21. PMID 22411801 DOI: 10.1073/Pnas.1119303109 |
0.763 |
|
| 2012 |
Kim YG, Saghatelian A. Functional analysis of protein targets by metabolomic approaches. Topics in Current Chemistry. 324: 137-62. PMID 22083210 DOI: 10.1007/128_2011_284 |
0.353 |
|
| 2011 |
Vinayavekhin N, Saghatelian A. Discovery of a protein-metabolite interaction between unsaturated fatty acids and the nuclear receptor Nur77 using a metabolomics approach. Journal of the American Chemical Society. 133: 17168-71. PMID 21973308 DOI: 10.1021/Ja208199H |
0.765 |
|
| 2011 |
Tinoco AD, Saghatelian A. Investigating endogenous peptides and peptidases using peptidomics. Biochemistry. 50: 7447-61. PMID 21786763 DOI: 10.1021/Bi200417K |
0.717 |
|
| 2011 |
Brown JD, Oligino E, Rader DJ, Saghatelian A, Plutzky J. VLDL hydrolysis by hepatic lipase regulates PPARδ transcriptional responses. Plos One. 6: e21209. PMID 21750705 DOI: 10.1371/Journal.Pone.0021209 |
0.392 |
|
| 2011 |
Lone AM, Bachovchin DA, Westwood DB, Speers AE, Spicer TP, Fernandez-Vega V, Chase P, Hodder PS, Rosen H, Cravatt BF, Saghatelian A. A substrate-free activity-based protein profiling screen for the discovery of selective PREPL inhibitors. Journal of the American Chemical Society. 133: 11665-74. PMID 21692504 DOI: 10.1021/Ja2036095 |
0.794 |
|
| 2011 |
Homan EA, Kim YG, Cardia JP, Saghatelian A. Monoalkylglycerol ether lipids promote adipogenesis. Journal of the American Chemical Society. 133: 5178-81. PMID 21428285 DOI: 10.1021/Ja111173C |
0.758 |
|
| 2011 |
Tinoco AD, Kim YG, Tagore DM, Wiwczar J, Lane WS, Danial NN, Saghatelian A. A peptidomics strategy to elucidate the proteolytic pathways that inactivate peptide hormones. Biochemistry. 50: 2213-22. PMID 21299233 DOI: 10.1021/Bi2000033 |
0.727 |
|
| 2011 |
Kim YG, Lou AC, Saghatelian A. A metabolomics strategy for detecting protein-metabolite interactions to identify natural nuclear receptor ligands. Molecular Biosystems. 7: 1046-9. PMID 21283866 DOI: 10.1039/C0Mb00324G |
0.309 |
|
| 2010 |
Lone AM, Nolte WM, Tinoco AD, Saghatelian A. Peptidomics of the prolyl peptidases. The Aaps Journal. 12: 483-91. PMID 20552307 DOI: 10.1208/S12248-010-9208-Y |
0.777 |
|
| 2010 |
Vinayavekhin N, Saghatelian A. Untargeted metabolomics. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. Unit 30.1.1-24. PMID 20373502 DOI: 10.1002/0471142727.mb3001s90 |
0.756 |
|
| 2010 |
Tinoco AD, Tagore DM, Saghatelian A. Expanding the dipeptidyl peptidase 4-regulated peptidome via an optimized peptidomics platform. Journal of the American Chemical Society. 132: 3819-30. PMID 20178363 DOI: 10.1021/Ja909524E |
0.739 |
|
| 2010 |
Vinayavekhin N, Homan EA, Saghatelian A. Exploring disease through metabolomics. Acs Chemical Biology. 5: 91-103. PMID 20020774 DOI: 10.1021/Cb900271R |
0.778 |
|
| 2009 |
Nolte WM, Tagore DM, Lane WS, Saghatelian A. Peptidomics of prolyl endopeptidase in the central nervous system. Biochemistry. 48: 11971-81. PMID 19911840 DOI: 10.1021/Bi901637C |
0.771 |
|
| 2009 |
Vinayavekhin N, Saghatelian A. Regulation of alkyl-dihydrothiazole-carboxylates (ATCs) by iron and the pyochelin gene cluster in Pseudomonas aeruginosa. Acs Chemical Biology. 4: 617-23. PMID 19621937 DOI: 10.1021/Cb900075N |
0.742 |
|
| 2009 |
Rodgers MA, Saghatelian A, Yang PL. Identification of an overabundant cholesterol precursor in hepatitis B virus replicating cells by untargeted lipid metabolite profiling. Journal of the American Chemical Society. 131: 5030-1. PMID 19301856 DOI: 10.1021/Ja809949R |
0.306 |
|
| 2009 |
Tagore DM, Nolte WM, Neveu JM, Rangel R, Guzman-Rojas L, Pasqualini R, Arap W, Lane WS, Saghatelian A. Peptidase substrates via global peptide profiling. Nature Chemical Biology. 5: 23-5. PMID 19011639 DOI: 10.1038/Nchembio.126 |
0.773 |
|
| 2008 |
Tagore R, Thomas HR, Homan EA, Munawar A, Saghatelian A. A global metabolite profiling approach to identify protein-metabolite interactions. Journal of the American Chemical Society. 130: 14111-3. PMID 18831549 DOI: 10.1021/Ja806463C |
0.763 |
|
| 2008 |
Voelcker NH, Guckian KM, Saghatelian A, Ghadiri MR. Sequence-addressable DNA logic. Small (Weinheim An Der Bergstrasse, Germany). 4: 427-31. PMID 18350554 DOI: 10.1002/Smll.200700113 |
0.464 |
|
| 2007 |
Chamero P, Marton TF, Logan DW, Flanagan K, Cruz JR, Saghatelian A, Cravatt BF, Stowers L. Identification of protein pheromones that promote aggressive behaviour. Nature. 450: 899-902. PMID 18064011 DOI: 10.1038/Nature05997 |
0.463 |
|
| 2007 |
Wan Y, Saghatelian A, Chong LW, Zhang CL, Cravatt BF, Evans RM. Maternal PPAR gamma protects nursing neonates by suppressing the production of inflammatory milk. Genes & Development. 21: 1895-908. PMID 17652179 DOI: 10.1101/Gad.1567207 |
0.454 |
|
| 2007 |
Everley PA, Gartner CA, Haas W, Saghatelian A, Elias JE, Cravatt BF, Zetter BR, Gygi SP. Assessing enzyme activities using stable isotope labeling and mass spectrometry. Molecular & Cellular Proteomics : McP. 6: 1771-7. PMID 17627935 DOI: 10.1074/Mcp.M700057-Mcp200 |
0.497 |
|
| 2007 |
Ostash B, Saghatelian A, Walker S. A streamlined metabolic pathway for the biosynthesis of moenomycin A. Chemistry & Biology. 14: 257-67. PMID 17379141 DOI: 10.1016/J.Chembiol.2007.01.008 |
0.338 |
|
| 2006 |
Chiang KP, Niessen S, Saghatelian A, Cravatt BF. An enzyme that regulates ether lipid signaling pathways in cancer annotated by multidimensional profiling. Chemistry & Biology. 13: 1041-50. PMID 17052608 DOI: 10.1016/J.Chembiol.2006.08.008 |
0.524 |
|
| 2006 |
Saghatelian A, McKinney MK, Bandell M, Patapoutian A, Cravatt BF. A FAAH-regulated class of N-acyl taurines that activates TRP ion channels. Biochemistry. 45: 9007-15. PMID 16866345 DOI: 10.1021/Bi0608008 |
0.786 |
|
| 2006 |
Leung D, Saghatelian A, Simon GM, Cravatt BF. Inactivation of N-acyl phosphatidylethanolamine phospholipase D reveals multiple mechanisms for the biosynthesis of endocannabinoids. Biochemistry. 45: 4720-6. PMID 16605240 DOI: 10.1021/Bi060163L |
0.687 |
|
| 2005 |
Saghatelian A, Cravatt BF. Assignment of protein function in the postgenomic era. Nature Chemical Biology. 1: 130-42. PMID 16408016 DOI: 10.1038/Nchembio0805-130 |
0.512 |
|
| 2005 |
Evans MJ, Saghatelian A, Sorensen EJ, Cravatt BF. Target discovery in small-molecule cell-based screens by in situ proteome reactivity profiling. Nature Biotechnology. 23: 1303-7. PMID 16200062 DOI: 10.1038/Nbt1149 |
0.511 |
|
| 2005 |
Saghatelian A, Cravatt BF. Discovery metabolite profiling--forging functional connections between the proteome and metabolome. Life Sciences. 77: 1759-66. PMID 15964030 DOI: 10.1016/J.Lfs.2005.05.019 |
0.532 |
|
| 2005 |
Go EP, Apon JV, Luo G, Saghatelian A, Daniels RH, Sahi V, Dubrow R, Cravatt BF, Vertes A, Siuzdak G. Desorption/ionization on silicon nanowires. Analytical Chemistry. 77: 1641-6. PMID 15762567 DOI: 10.1021/Ac048460O |
0.449 |
|
| 2005 |
Saghatelian A, Cravatt BF. Global strategies to integrate the proteome and metabolome. Current Opinion in Chemical Biology. 9: 62-8. PMID 15701455 DOI: 10.1016/J.Cbpa.2004.12.004 |
0.524 |
|
| 2005 |
Saghatelian A, Cravatt BF. Erratum: Corrigendum: Assignment of protein function in the postgenomic era Nature Chemical Biology. 1: 233-233. DOI: 10.1038/Nchembio0905-233 |
0.457 |
|
| 2004 |
Saghatelian A, Trauger SA, Want EJ, Hawkins EG, Siuzdak G, Cravatt BF. Assignment of endogenous substrates to enzymes by global metabolite profiling. Biochemistry. 43: 14332-9. PMID 15533037 DOI: 10.1021/Bi0480335 |
0.523 |
|
| 2004 |
Cravatt BF, Saghatelian A, Hawkins EG, Clement AB, Bracey MH, Lichtman AH. Functional disassociation of the central and peripheral fatty acid amide signaling systems. Proceedings of the National Academy of Sciences of the United States of America. 101: 10821-6. PMID 15247426 DOI: 10.1073/Pnas.0401292101 |
0.478 |
|
| 2004 |
Lichtman AH, Leung D, Shelton CC, Saghatelian A, Hardouin C, Boger DL, Cravatt BF. Reversible inhibitors of fatty acid amide hydrolase that promote analgesia: evidence for an unprecedented combination of potency and selectivity. The Journal of Pharmacology and Experimental Therapeutics. 311: 441-8. PMID 15229230 DOI: 10.1124/Jpet.104.069401 |
0.588 |
|
| 2004 |
Saghatelian A, Jessani N, Joseph A, Humphrey M, Cravatt BF. Activity-based probes for the proteomic profiling of metalloproteases. Proceedings of the National Academy of Sciences of the United States of America. 101: 10000-5. PMID 15220480 DOI: 10.1073/Pnas.0402784101 |
0.772 |
|
| 2004 |
Sánchez-Quesada J, Saghatelian A, Cheley S, Bayley H, Ghadiri MR. Single DNA rotaxanes of a transmembrane pore protein. Angewandte Chemie (International Ed. in English). 43: 3063-7. PMID 15188482 DOI: 10.1002/Anie.200453907 |
0.498 |
|
| 2004 |
Sánchez-Quesada J, Saghatelian A, Cheley S, Bayley H, Ghadiri MR. Cover Picture: Single DNA Rotaxanes of a Transmembrane Pore Protein (Angew. Chem. Int. Ed. 23/2004) Angewandte Chemie International Edition. 43: 2977-2977. DOI: 10.1002/Anie.200490069 |
0.498 |
|
| 2004 |
Sánchez-Quesada J, Saghatelian A, Cheley S, Bayley H, Ghadiri MR. Titelbild: Single DNA Rotaxanes of a Transmembrane Pore Protein (Angew. Chem. 23/2004) Angewandte Chemie. 116: 3037-3037. DOI: 10.1002/Ange.200490069 |
0.496 |
|
| 2003 |
Saghatelian A, Völcker NH, Guckian KM, Lin VS, Ghadiri MR. DNA-based photonic logic gates: AND, NAND, and INHIBIT. Journal of the American Chemical Society. 125: 346-7. PMID 12517142 DOI: 10.1021/Ja029009M |
0.476 |
|
| 2003 |
Saghatelian A, Guckian KM, Thayer DA, Ghadiri MR. DNA detection and signal amplification via an engineered allosteric enzyme. Journal of the American Chemical Society. 125: 344-5. PMID 12517141 DOI: 10.1021/Ja027885U |
0.501 |
|
| 2001 |
Merlic CA, Aldrich CC, Albaneze-Walker J, Saghatelian A, Mammen J. Total synthesis of the calphostins: application of fischer carbene complexes and thermodynamic control of atropisomers. The Journal of Organic Chemistry. 66: 1297-309. PMID 11312960 DOI: 10.1021/Jo0014663 |
0.567 |
|
| 2001 |
Saghatelian A, Yokobayashi Y, Soltani K, Ghadiri MR. A chiroselective peptide replicator. Nature. 409: 797-801. PMID 11236988 DOI: 10.1038/35057238 |
0.708 |
|
| 2001 |
Saghatelian A, Buriak J, Lin VSY, Ghadiri MR. Transition metal mediated surface modification of porous silicon Tetrahedron. 57: 5131-5136. DOI: 10.1016/S0040-4020(01)00366-0 |
0.599 |
|
| 2000 |
Merlic CA, Aldrich CC, Albaneze-Walker J, Saghatelian A. Carbene Complexes in the Synthesis of Complex Natural Products: Total Synthesis of the Calphostins. Journal of the American Chemical Society. 122: 3224-3225. PMID 23335811 DOI: 10.1021/Ja994313+ |
0.608 |
|
| 2000 |
Merlic CA, Aldrich CC, Albaneze-Walker J, Saghatelian A. Carbene complexes in the synthesis of complex natural products: Total synthesis of the calphostins [5] Journal of the American Chemical Society. 122: 3224-3225. DOI: 10.1021/ja994313+ |
0.549 |
|
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