Year |
Citation |
Score |
2020 |
Sun L, Qu L, Brigstock DR, Li H, Li Y, Gao R. Biological and Proteomic Characteristics of an Immortalized Human Pancreatic Stellate Cell Line. International Journal of Medical Sciences. 17: 137-144. PMID 31929747 DOI: 10.7150/ijms.36337 |
0.367 |
|
2018 |
Chen L, Chen R, Kemper S, Cong M, You H, Brigstock DR. Therapeutic effects of serum extracellular vesicles in liver fibrosis. Journal of Extracellular Vesicles. 7: 1461505. PMID 29696080 DOI: 10.1080/20013078.2018.1461505 |
0.339 |
|
2017 |
Chen L, Chen R, Kemper S, Brigstock DR. Pathways of production and delivery of hepatocyte exosomes. Journal of Cell Communication and Signaling. PMID 29063370 DOI: 10.1007/s12079-017-0421-7 |
0.323 |
|
2017 |
Chen L, Brigstock DR. Cellular or Exosomal microRNAs Associated with CCN Gene Expression in Liver Fibrosis. Methods in Molecular Biology (Clifton, N.J.). 1489: 465-480. PMID 27734397 DOI: 10.1007/978-1-4939-6430-7_38 |
0.352 |
|
2017 |
Chen L, Brigstock DR. Analysis of Pathological Activities of CCN Proteins in Fibrotic Diseases: Liver Fibrosis. Methods in Molecular Biology (Clifton, N.J.). 1489: 445-463. PMID 27734396 DOI: 10.1007/978-1-4939-6430-7_37 |
0.315 |
|
2016 |
Chen L, Brigstock DR. Integrins and heparan sulfate proteoglycans on hepatic stellate cells (HSC) are novel receptors for HSC-derived exosomes. Febs Letters. PMID 27714787 DOI: 10.1002/1873-3468.12448 |
0.32 |
|
2015 |
Chen L, Chen R, Kemper S, Charrier A, Brigstock DR. Suppression of fibrogenic signaling in hepatic stellate cells by Twist1-dependent microRNA-214 expression: Role of exosomes in horizontal transfer of Twist1. American Journal of Physiology. Gastrointestinal and Liver Physiology. ajpgi.00140.2015. PMID 26229009 DOI: 10.1152/Ajpgi.00140.2015 |
0.778 |
|
2014 |
Charrier A, Chen R, Chen L, Kemper S, Hattori T, Takigawa M, Brigstock DR. Exosomes mediate intercellular transfer of pro-fibrogenic connective tissue growth factor (CCN2) between hepatic stellate cells, the principal fibrotic cells in the liver. Surgery. 156: 548-55. PMID 24882759 DOI: 10.1016/J.Surg.2014.04.014 |
0.794 |
|
2014 |
Charrier A, Chen R, Kemper S, Brigstock DR. Regulation of pancreatic inflammation by connective tissue growth factor (CTGF/CCN2). Immunology. 141: 564-76. PMID 24754049 DOI: 10.1111/Imm.12215 |
0.772 |
|
2014 |
Cheung LC, Strickland DH, Howlett M, Ford J, Charles AK, Lyons KM, Brigstock DR, Goldschmeding R, Cole CH, Alexander WS, Kees UR. Connective tissue growth factor is expressed in bone marrow stromal cells and promotes interleukin-7-dependent B lymphopoiesis. Haematologica. 99: 1149-56. PMID 24727816 DOI: 10.3324/Haematol.2013.102327 |
0.346 |
|
2014 |
Charrier A, Chen R, Chen L, Kemper S, Hattori T, Takigawa M, Brigstock DR. Connective tissue growth factor (CCN2) and microRNA-21 are components of a positive feedback loop in pancreatic stellate cells (PSC) during chronic pancreatitis and are exported in PSC-derived exosomes. Journal of Cell Communication and Signaling. 8: 147-56. PMID 24464300 DOI: 10.1007/S12079-014-0220-3 |
0.767 |
|
2014 |
Chen L, Charrier A, Zhou Y, Chen R, Yu B, Agarwal K, Tsukamoto H, Lee LJ, Paulaitis ME, Brigstock DR. Epigenetic regulation of connective tissue growth factor by MicroRNA-214 delivery in exosomes from mouse or human hepatic stellate cells. Hepatology (Baltimore, Md.). 59: 1118-29. PMID 24122827 DOI: 10.1002/Hep.26768 |
0.755 |
|
2014 |
Charrier A, Chen L, Chen R, Hattori T, Takigawa M, Brigstock D. Production of Nano-Sized Exosomes by Fibrogenic Cells of the Liver or Pancreas: Role in Intercellular Delivery of Pro-Fibrotic Molecules and Potential as Novel Drug Delivery Agents In Vivo Journal of Surgical Research. 186: 678. DOI: 10.1016/J.Jss.2013.11.871 |
0.339 |
|
2013 |
Abbott RD, Purmessur D, Monsey RD, Brigstock DR, Laudier DM, Iatridis JC. Degenerative grade affects the responses of human nucleus pulposus cells to Link-N, CTGF, and TGFβ3 Journal of Spinal Disorders and Techniques. 26: E86-E94. PMID 22907063 DOI: 10.1097/Bsd.0B013E31826E0Ca4 |
0.363 |
|
2013 |
Charrier A, Brigstock DR. Regulation of pancreatic function by connective tissue growth factor (CTGF, CCN2). Cytokine & Growth Factor Reviews. 24: 59-68. PMID 22884427 DOI: 10.1016/J.Cytogfr.2012.07.001 |
0.799 |
|
2013 |
Charrier A, Brigstock D. A Novel Biological Role for Connective Tissue Growth Factor (CTGF): Modulation of Inflammatory Cell Recruitment During Alcohol-Induced Injury of the Pancreas Journal of Surgical Research. 179: 232. DOI: 10.1016/j.jss.2012.10.426 |
0.337 |
|
2012 |
Xiu M, Liu YH, Brigstock DR, He FH, Zhang RJ, Gao RP. Connective tissue growth factor is overexpressed in human hepatocellular carcinoma and promotes cell invasion and growth. World Journal of Gastroenterology. 18: 7070-8. PMID 23323010 DOI: 10.3748/wjg.v18.i47.7070 |
0.316 |
|
2012 |
Nagaraja T, Chen L, Balasubramanian A, Groopman JE, Ghoshal K, Jacob ST, Leask A, Brigstock DR, Anand AR, Ganju RK. Activation of the connective tissue growth factor (CTGF)-transforming growth factor β 1 (TGF-β 1) axis in hepatitis C virus-expressing hepatocytes. Plos One. 7: e46526. PMID 23056332 DOI: 10.1371/Journal.Pone.0046526 |
0.311 |
|
2012 |
Huang G, Brigstock DR. Regulation of hepatic stellate cells by connective tissue growth factor. Frontiers in Bioscience (Landmark Edition). 17: 2495-507. PMID 22652794 |
0.44 |
|
2012 |
Huang G, Besner GE, Brigstock DR. Heparin-binding epidermal growth factor-like growth factor suppresses experimental liver fibrosis in mice. Laboratory Investigation; a Journal of Technical Methods and Pathology. 92: 703-12. PMID 22330337 DOI: 10.1038/Labinvest.2012.3 |
0.337 |
|
2012 |
Charrier A, Brigstock D. Tu1495 Connective Tissue Growth Factor Production by Pancreatic Acinar Cells is Associated With Regulation of Immune Function in a Mouse Model of Alcoholic Chronic Pancreatitis Gastroenterology. 142: S-848-S-849. DOI: 10.1016/S0016-5085(12)63289-2 |
0.788 |
|
2012 |
Chen L, Charrier A, Zhou Y, Brigstock D. The Pro-Fibrotic Molecule, Connective Tissue Growth Factor (CTGF), is Regulated by MicroRNA-214 (miR-214) in Hepatic Stellate Cells Journal of Surgical Research. 172: 205. DOI: 10.1016/j.jss.2011.11.281 |
0.365 |
|
2011 |
Chen L, Charrier AL, Leask A, French SW, Brigstock DR. Ethanol-stimulated differentiated functions of human or mouse hepatic stellate cells are mediated by connective tissue growth factor. Journal of Hepatology. 55: 399-406. PMID 21156189 DOI: 10.1016/J.Jhep.2010.11.025 |
0.8 |
|
2011 |
Huang G, Brigstock DR. Integrin expression and function in the response of primary culture hepatic stellate cells to connective tissue growth factor (CCN2). Journal of Cellular and Molecular Medicine. 15: 1087-95. PMID 20406330 DOI: 10.1111/j.1582-4934.2010.01072.x |
0.311 |
|
2011 |
Chen L, Tsukamoto H, Brigstock D. Ethanol-Dependent Expression of Connective Tissue Growth Factor is Associated With Down-Regulation of MicroRNA 214 Gastroenterology. 140: S-916. DOI: 10.1016/S0016-5085(11)63799-2 |
0.446 |
|
2010 |
Charrier AL, Brigstock DR. Connective tissue growth factor production by activated pancreatic stellate cells in mouse alcoholic chronic pancreatitis. Laboratory Investigation; a Journal of Technical Methods and Pathology. 90: 1179-88. PMID 20368699 DOI: 10.1038/Labinvest.2010.82 |
0.778 |
|
2009 |
Gao RP, Brigstock DR. Connective tissue growth factor hammerhead ribozyme attenuates human hepatic stellate cell function. World Journal of Gastroenterology. 15: 3807-13. PMID 19673024 |
0.406 |
|
2009 |
Tong Z, Chen R, Alt DS, Kemper S, Perbal B, Brigstock DR. Susceptibility to liver fibrosis in mice expressing a connective tissue growth factor transgene in hepatocytes. Hepatology (Baltimore, Md.). 50: 939-47. PMID 19670427 DOI: 10.1002/hep.23102 |
0.331 |
|
2009 |
Zhou Y, Brigstock D, Besner GE. Heparin-binding EGF-like growth factor is a potent dilator of terminal mesenteric arterioles. Microvascular Research. 78: 78-85. PMID 19389413 DOI: 10.1016/J.Mvr.2009.04.006 |
0.35 |
|
2009 |
Wang J, Leclercq I, Brymora JM, Xu N, Ramezani-Moghadam M, London RM, Brigstock D, George J. Kupffer cells mediate leptin-induced liver fibrosis. Gastroenterology. 137: 713-23. PMID 19375424 DOI: 10.1053/J.Gastro.2009.04.011 |
0.372 |
|
2009 |
Brigstock DR. Strategies for blocking the fibrogenic actions of connective tissue growth factor (CCN2): From pharmacological inhibition in vitro to targeted siRNA therapy in vivo. Journal of Cell Communication and Signaling. 3: 5-18. PMID 19294531 DOI: 10.1007/s12079-009-0043-9 |
0.313 |
|
2009 |
Lawrencia C, Charrier A, Huang G, Brigstock DR. Ethanol-mediated expression of connective tissue growth factor (CCN2) in mouse pancreatic stellate cells. Growth Factors (Chur, Switzerland). 27: 91-9. PMID 19280452 DOI: 10.1080/08977190902786319 |
0.767 |
|
2009 |
Crawford LA, Guney MA, Oh YA, Deyoung RA, Valenzuela DM, Murphy AJ, Yancopoulos GD, Lyons KM, Brigstock DR, Economides A, Gannon M. Connective tissue growth factor (CTGF) inactivation leads to defects in islet cell lineage allocation and beta-cell proliferation during embryogenesis. Molecular Endocrinology (Baltimore, Md.). 23: 324-36. PMID 19131512 DOI: 10.1210/me.2008-0045 |
0.386 |
|
2009 |
Huang G, Brigstock D. S1606 Integrin α5β1 Is a CTGF Receptor On Early Primary Culture Hepatic Stellate Cells and Interacts with Fibronectin and Heparan Sulfate Proteglycans to Regulate CTGF Function Gastroenterology. 136: A-823. DOI: 10.1016/S0016-5085(09)63796-3 |
0.367 |
|
2009 |
Huang G, Brigstock D. S1601 Differential Modulation of Integrins Gene Expression By Connective Tissue Growth Factor in Early and Activated Primary Culture Hepatic Stellate Cells Gastroenterology. 136: A-822. DOI: 10.1016/S0016-5085(09)63791-4 |
0.49 |
|
2008 |
Leask A, Chen S, Pala D, Brigstock DR. Regulation of CCN2 mRNA expression and promoter activity in activated hepatic stellate cells. Journal of Cell Communication and Signaling. 2: 49-56. PMID 18798011 DOI: 10.1007/s12079-008-0029-z |
0.363 |
|
2008 |
Lawrencia C, Brigstock D. 363 Selective Targeting of CTGF SIRNA to Activated Stellate Cells Reduces Carbon Tetrachloride (Ccl4) Induced Hepatic Fibrosis In Vivo Gastroenterology. 134: A-764. DOI: 10.1016/S0016-5085(08)63569-6 |
0.334 |
|
2006 |
Tong ZY, Brigstock DR. Intrinsic biological activity of the thrombospondin structural homology repeat in connective tissue growth factor. The Journal of Endocrinology. 188: R1-8. PMID 16522717 DOI: 10.1677/joe.1.06719 |
0.41 |
|
2006 |
Gao R, Brigstock DR. A novel integrin α5β1 binding domain in module 4 of connective tissue growth factor (CCN2/CTGF) promotes adhesion and migration of activated pancreatic stellate cells Gut. 55: 856-862. PMID 16361307 DOI: 10.1136/gut.2005.079178 |
0.386 |
|
2005 |
Gao R, Brigstock DR. Activation of nuclear factor kappa B (NF-kappaB) by connective tissue growth factor (CCN2) is involved in sustaining the survival of primary rat hepatic stellate cells. Cell Communication and Signaling : Ccs. 3: 14. PMID 16303051 DOI: 10.1186/1478-811X-3-14 |
0.414 |
|
2005 |
Gao R, Brigstock DR. Connective tissue growth factor (CCN2) in rat pancreatic stellate cell function: integrin alpha5beta1 as a novel CCN2 receptor. Gastroenterology. 129: 1019-30. PMID 16143139 DOI: 10.1053/j.gastro.2005.06.067 |
0.417 |
|
2005 |
Cicha I, Yilmaz A, Klein M, Raithel D, Brigstock DR, Daniel WG, Goppelt-Struebe M, Garlichs CD. Connective tissue growth factor is overexpressed in complicated atherosclerotic plaques and induces mononuclear cell chemotaxis in vitro. Arteriosclerosis, Thrombosis, and Vascular Biology. 25: 1008-13. PMID 15761189 DOI: 10.1161/01.ATV.0000162173.27682.7b |
0.426 |
|
2005 |
Rachfal AW, Brigstock DR. Structural and functional properties of CCN proteins. Vitamins and Hormones. 70: 69-103. PMID 15727802 DOI: 10.1016/S0083-6729(05)70003-0 |
0.791 |
|
2004 |
Gao R, Ball DK, Perbal B, Brigstock DR. Connective tissue growth factor induces c-fos gene activation and cell proliferation through p44/42 MAP kinase in primary rat hepatic stellate cells. Journal of Hepatology. 40: 431-8. PMID 15123357 DOI: 10.1016/J.Jhep.2003.11.012 |
0.812 |
|
2004 |
Wang JF, Olson ME, Ma L, Brigstock DR, Hart DA. Connective tissue growth factor siRNA modulates mRNA levels for a subset of molecules in normal and TGF-beta 1-stimulated porcine skin fibroblasts. Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society. 12: 205-16. PMID 15086772 DOI: 10.1111/j.1067-1927.2004.012113.x |
0.316 |
|
2004 |
Rachfal AW, Luquette MH, Brigstock DR. Expression of connective tissue growth factor (CCN2) in desmoplastic small round cell tumour. Journal of Clinical Pathology. 57: 422-5. PMID 15047749 |
0.795 |
|
2003 |
Gao R, Brigstock DR. Low density lipoprotein receptor-related protein (LRP) is a heparin-dependent adhesion receptor for connective tissue growth factor (CTGF) in rat activated hepatic stellate cells. Hepatology Research : the Official Journal of the Japan Society of Hepatology. 27: 214-220. PMID 14585398 |
0.393 |
|
2003 |
Brigstock DR. The CCN family: a new stimulus package. The Journal of Endocrinology. 178: 169-75. PMID 12904165 DOI: 10.1677/JOE.0.1780169 |
0.368 |
|
2003 |
Rachfal AW, Brigstock DR. Connective tissue growth factor (CTGF/CCN2) in hepatic fibrosis. Hepatology Research : the Official Journal of the Japan Society of Hepatology. 26: 1-9. PMID 12787797 DOI: 10.1016/S1386-6346(03)00115-3 |
0.8 |
|
2003 |
Wang JF, Olson ME, Ball DK, Brigstock DR, Hart DA. Recombinant connective tissue growth factor modulates porcine skin fibroblast gene expression. Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society. 11: 220-9. PMID 12753604 DOI: 10.1046/J.1524-475X.2003.11311.X |
0.799 |
|
2003 |
Ball DK, Moussad EE, Rageh MA, Kemper SA, Brigstock DR. Establishment of a recombinant expression system for connective tissue growth factor (CTGF) that models CTGF processing in utero. Reproduction (Cambridge, England). 125: 271-84. PMID 12578541 |
0.813 |
|
2003 |
Ball DK, Rachfal AW, Kemper SA, Brigstock DR. The heparin-binding 10 kDa fragment of connective tissue growth factor (CTGF) containing module 4 alone stimulates cell adhesion. The Journal of Endocrinology. 176: R1-7. PMID 12553878 |
0.757 |
|
2003 |
Gao R, Brigstock DR. Low density lipoprotein receptor-related protein (LRP) is a heparin-dependent adhesion receptor for connective tissue growth factor (CTGF) in rat activated hepatic stellate cells Hepatology Research. 27: 214-220. DOI: 10.1016/S1386-6346(03)00241-9 |
0.387 |
|
2003 |
GAO R, BRIGSTOCK D. 1270 Connective tissue growth factor (CTGF) induces adhesion of rat activated hepatic stellate cells via integrin alpha V beta 3 and heparan sulfate proteoglycans through its carboxyl-terminal domain Hepatology. 38: 772-772. DOI: 10.1016/S0270-9139(03)81308-3 |
0.325 |
|
2002 |
Brigstock DR. Regulation of angiogenesis and endothelial cell function by connective tissue growth factor (CTGF) and cysteine-rich 61 (CYR61). Angiogenesis. 5: 153-65. PMID 12831056 |
0.426 |
|
2002 |
Koliopanos A, Friess H, di Mola FF, Tang WH, Kubulus D, Brigstock D, Zimmermann A, Büchler MW. Connective tissue growth factor gene expression alters tumor progression in esophageal cancer. World Journal of Surgery. 26: 420-7. PMID 11910473 DOI: 10.1007/S00268-001-0242-X |
0.381 |
|
2002 |
di Mola FF, Friess H, Riesle E, Koliopanos A, Büchler P, Zhu Z, Brigstock DR, Korc M, Büchler MW. Connective tissue growth factor is involved in pancreatic repair and tissue remodeling in human and rat acute necrotizing pancreatitis. Annals of Surgery. 235: 60-7. PMID 11753043 DOI: 10.1097/00000658-200201000-00008 |
0.324 |
|
2001 |
Rageh MA, Moussad EE, Wilson AK, Brigstock DR. Steroidal regulation of connective tissue growth factor (CCN2; CTGF) synthesis in the mouse uterus. Molecular Pathology : Mp. 54: 338-46. PMID 11577177 DOI: 10.1136/mp.54.5.338 |
0.339 |
|
2000 |
Uzumcu M, Homsi MF, Ball DK, Coskun S, Jaroudi K, Hollanders JM, Brigstock DR. Localization of connective tissue growth factor in human uterine tissues. Molecular Human Reproduction. 6: 1093-8. PMID 11101692 |
0.798 |
|
2000 |
Moussad EE, Brigstock DR. Connective tissue growth factor: what's in a name? Molecular Genetics and Metabolism. 71: 276-92. PMID 11001822 DOI: 10.1006/MGME.2000.3059 |
0.415 |
|
2000 |
Williams EJ, Gaça MD, Brigstock DR, Arthur MJ, Benyon RC. Increased expression of connective tissue growth factor in fibrotic human liver and in activated hepatic stellate cells. Journal of Hepatology. 32: 754-61. PMID 10845662 DOI: 10.1016/S0168-8278(00)80244-5 |
0.409 |
|
2000 |
Harding PA, Surveyor GA, Brigstock DR. Characterization of pig connective tissue growth factor (CTGF) cDNA, mRNA and protein from uterine tissue. Dna Sequence : the Journal of Dna Sequencing and Mapping. 8: 385-90. PMID 10728823 DOI: 10.3109/10425179809020899 |
0.363 |
|
2000 |
Surveyor GA, Brigstock DR. Immunohistochemical localization of connective tissue growth factor (CTGF) in the mouse embryo between days 7.5 and 14.5 of gestation. Growth Factors (Chur, Switzerland). 17: 115-24. PMID 10595311 DOI: 10.3109/08977199909103520 |
0.402 |
|
1999 |
Harding PA, Davis-Fleischer KM, Crissman-Combs MA, Miller MT, Brigstock DR, Besner GE. Induction of anchorage independent growth by heparin-binding EGF-like growth factor (HB-EGF). Growth Factors (Chur, Switzerland). 17: 49-61. PMID 10495962 DOI: 10.3109/08977199909001062 |
0.394 |
|
1998 |
Surveyor GA, Wilson AK, Brigstock DR. Localization of connective tissue growth factor during the period of embryo implantation in the mouse. Biology of Reproduction. 59: 1207-13. PMID 9780329 DOI: 10.1095/BIOLREPROD59.5.1207 |
0.309 |
|
1998 |
Ball DK, Surveyor GA, Diehl JR, Steffen CL, Uzumcu M, Mirando MA, Brigstock DR. Characterization of 16- to 20-kilodalton (kDa) connective tissue growth factors (CTGFs) and demonstration of proteolytic activity for 38-kDa CTGF in pig uterine luminal flushings. Biology of Reproduction. 59: 828-35. PMID 9746732 DOI: 10.1095/Biolreprod59.4.828 |
0.787 |
|
1998 |
Steffen CL, Ball-Mirth DK, Harding PA, Bhattacharyya N, Pillai S, Brigstock DR. Characterization of cell-associated and soluble forms of connective tissue growth factor (CTGF) produced by fibroblast cells in vitro Growth Factors. 15: 199-213. PMID 9570041 DOI: 10.3109/08977199809002117 |
0.351 |
|
1997 |
Downing MT, Brigstock DR, Luquette MH, Crissman-Combs M, Besner GE. Immunohistochemical localization of heparin-binding epidermal growth factor-like growth factor in normal skin and skin cancers Histochemical Journal. 29: 735-744. PMID 9429077 DOI: 10.1023/A:1026417202351 |
0.327 |
|
1997 |
Brigstock DR, Steffen CL, Kim GY, Vegunta RK, Diehl JR, Harding PA. Purification and characterization of novel heparin-binding growth factors in uterine secretory fluids. Identification as heparin-regulated Mr 10,000 forms of connective tissue growth factor. The Journal of Biological Chemistry. 272: 20275-82. PMID 9242708 DOI: 10.1074/jbc.272.32.20275 |
0.359 |
|
1996 |
Davis KM, Brigstock DR, Johnson PR, Crissman-Combs MA, McCarthy DW, Downing MT, Besner GE. Production of glycosylated heparin-binding EGF-like growth factor in HeLa cells using vaccinia virus Protein Expression and Purification. 8: 57-67. PMID 8812835 DOI: 10.1006/Prep.1996.0074 |
0.315 |
|
1992 |
Brigstock DR. Growth factors in the uterus: steroidal regulation and biological actions. Bailliere's Clinical Endocrinology and Metabolism. 5: 791-808. PMID 1755816 DOI: 10.1016/S0950-351X(10)80015-1 |
0.343 |
|
1990 |
Brigstock DR, Heap RB, Barker PJ, Brown KD. Purification and characterization of heparin-binding growth factors from porcine uterus Biochemical Journal. 266: 273-282. PMID 2310377 DOI: 10.1042/bj2660273 |
0.302 |
|
1989 |
Brigstock DR, Heap RB, Brown KD. Polypeptide growth factors in uterine tissues and secretions Journal of Reproduction and Fertility. 85: 747-758. PMID 2649663 DOI: 10.1530/jrf.0.0850747 |
0.341 |
|
Show low-probability matches. |