Kevin Claffey - Publications

Affiliations: 
University of Connecticut, Storrs, CT, United States 
Area:
Cell Biology, Oncology

53 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Blanchette-Farra N, Kita D, Konstorum A, Tesfay L, Lemler D, Hegde P, Claffey KP, Torti FM, Torti SV. Contribution of three-dimensional architecture and tumor-associated fibroblasts to hepcidin regulation in breast cancer. Oncogene. PMID 29695834 DOI: 10.1038/S41388-018-0243-Y  0.397
2016 Kopsiaftis S, Hegde P, Taylor JA, Claffey KP. AMPKα Is Suppressed in Bladder Cancer through Macrophage-Mediated Mechanisms. Translational Oncology. 9: 606-616. PMID 27916296 DOI: 10.1016/j.tranon.2016.07.007  0.354
2016 Kopsiaftis S, Sullivan KL, Garg I, Taylor JA, Claffey KP. AMPKalpha2 Regulates Bladder Cancer Growth Through SKP2-mediated Degradation of p27. Molecular Cancer Research : McR. PMID 27638620 DOI: 10.1158/1541-7786.MCR-16-0111  0.363
2015 Dong H, Claffey KP, Brocke S, Epstein PM. Inhibition of breast cancer cell migration by activation of cAMP signaling. Breast Cancer Research and Treatment. 152: 17-28. PMID 26022351 DOI: 10.1007/S10549-015-3445-9  0.315
2015 Jensen T, Vadasz S, Phoenix K, Claffey K, Parikh N, Finck C. Descriptive analysis of tumor cells with stem like phenotypes in metastatic and benign adrenal tumors. Journal of Pediatric Surgery. 50: 1493-501. PMID 25976447 DOI: 10.1016/J.Jpedsurg.2015.04.012  0.386
2015 Dong H, Claffey KP, Brocke S, Epstein PM. Inhibition of breast cancer cell migration by activation of cAMP signaling Breast Cancer Research and Treatment. 152: 17-28. DOI: 10.1007/s10549-015-3445-9  0.333
2014 Choudhary D, Hegde P, Choudhary S, Claffey K, Srivastava P, Pilbeam CC, Taylor JA. Abstract 53: Increased expression of L-selectin (CD62L) in high grade bladder cancer: a potential biomarker for lymph node metastasis Cancer Research. 74: 53-53. DOI: 10.1158/1538-7445.Am2014-53  0.455
2014 Choudhary D, Hegde P, Choudhary S, Claffey K, Srivastava P, Pilbeam C, Taylor J. MP39-19 L-SELECTIN (CD62L) EXPRESSION IN HIGH GRADE UROTHELIAL CARCINOMA AS A POTENTIAL MARKER OF METASTATIC DISEASE Journal of Urology. 191. DOI: 10.1016/J.Juro.2014.02.1334  0.406
2013 Dong H, Claffey KP, Brocke S, Epstein PM. Expression of phosphodiesterase 6 (PDE6) in human breast cancer cells. Springerplus. 2: 680. PMID 24683528 DOI: 10.1186/2193-1801-2-680  0.363
2013 Fox MM, Phoenix KN, Kopsiaftis SG, Claffey KP. AMP-Activated Protein Kinase α 2 Isoform Suppression in Primary Breast Cancer Alters AMPK Growth Control and Apoptotic Signaling. Genes & Cancer. 4: 3-14. PMID 23946867 DOI: 10.1177/1947601913486346  0.763
2012 Murphy M, Phelps A, Swede H, Claffey K. Hypoxia-induced response of cell cycle and apoptosis regulators in melanoma International Journal of Dermatology. 51: 1263-1267. PMID 22994674 DOI: 10.1111/J.1365-4632.2010.04777.X  0.356
2012 Phoenix KN, Devarakonda CV, Fox MM, Stevens LE, Claffey KP. AMPKα2 Suppresses Murine Embryonic Fibroblast Transformation and Tumorigenesis. Genes & Cancer. 3: 51-62. PMID 22893790 DOI: 10.1177/1947601912452883  0.708
2011 Tannenbaum S, Rampurwala M, Hegde P, Jabbour N, Phoenix N, Claffey K. Vascular and lymphatic phenotype of HER2+ breast cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: e11046. PMID 28023406 DOI: 10.1200/jco.2011.29.15_suppl.e11046  0.39
2010 Rezaul K, Thumar JK, Lundgren DH, Eng JK, Claffey KP, Wilson L, Han DK. Differential protein expression profiles in estrogen receptor-positive and -negative breast cancer tissues using label-free quantitative proteomics. Genes & Cancer. 1: 251-71. PMID 21779449 DOI: 10.1177/1947601910365896  0.334
2010 Phoenix KN, Vumbaca F, Fox MM, Evans R, Claffey KP. Dietary energy availability affects primary and metastatic breast cancer and metformin efficacy. Breast Cancer Research and Treatment. 123: 333-44. PMID 20204498 DOI: 10.1007/S10549-009-0647-Z  0.707
2009 Adams BD, Claffey KP, White BA. Argonaute-2 expression is regulated by epidermal growth factor receptor and mitogen-activated protein kinase signaling and correlates with a transformed phenotype in breast cancer cells. Endocrinology. 150: 14-23. PMID 18787018 DOI: 10.1210/en.2008-0984  0.388
2009 Rodriguez-Pinto D, Sparkowski J, Keough MP, Phoenix KN, Vumbaca F, Han DK, Gundelfinger ED, Beesley P, Claffey KP. Identification of novel tumor antigens with patient-derived immune-selected antibodies. Cancer Immunology, Immunotherapy : Cii. 58: 221-34. PMID 18568347 DOI: 10.1007/S00262-008-0543-0  0.741
2009 Phoenix KN, Vumbaca F, Claffey KP. Therapeutic metformin/AMPK activation promotes the angiogenic phenotype in the ERalpha negative MDA-MB-435 breast cancer model. Breast Cancer Research and Treatment. 113: 101-11. PMID 18256928 DOI: 10.1007/s10549-008-9916-5  0.454
2009 Tannenbaum S, Phoenix K, Hegde P, Claffey K. The correlation of tumor vascularity as imaged by near-infrared technology with tissue distribution of angiogenic and growth promoters. Cancer Research. 69: 907. DOI: 10.1158/0008-5472.Sabcs-907  0.479
2009 Machida K, Claffey K, Thompson C, Hong S, Shin D, Mayer B. Phosphoproteomic study of breast cancer: quantitative analysis of SH2 binding proteins. Cancer Research. 69: 2034. DOI: 10.1158/0008-5472.Sabcs-2034  0.369
2009 Machida K, Claffey K, Thompson C, Shin D, Mayer B. Phosphoproteomic study of breast cancer: high-throughput SH2 screening. Cancer Research. 69: 2031. DOI: 10.1158/0008-5472.Sabcs-2031  0.423
2008 Peluso JJ, Liu X, Saunders MM, Claffey KP, Phoenix K. Regulation of ovarian cancer cell viability and sensitivity to cisplatin by progesterone receptor membrane component-1 Journal of Clinical Endocrinology and Metabolism. 93: 1592-1599. PMID 18319313 DOI: 10.1210/jc.2007-2771  0.361
2008 Vumbaca F, Phoenix KN, Rodriguez-Pinto D, Han DK, Claffey KP. Double-stranded RNA-binding protein regulates vascular endothelial growth factor mRNA stability, translation, and breast cancer angiogenesis. Molecular and Cellular Biology. 28: 772-83. PMID 18039850 DOI: 10.1128/MCB.02078-06  0.393
2007 Skoura A, Sanchez T, Claffey K, Mandala SM, Proia RL, Hla T. Essential role of sphingosine 1-phosphate receptor 2 in pathological angiogenesis of the mouse retina. The Journal of Clinical Investigation. 117: 2506-16. PMID 17710232 DOI: 10.1172/Jci31123  0.398
2007 Taylor JA, Kuchel GA, Hegde P, Voznesensky OS, Claffey K, Tsimikas J, Leng L, Bucala R, Pilbeam C. Null mutation for macrophage migration inhibitory factor (MIF) is associated with less aggressive bladder cancer in mice. Bmc Cancer. 7: 135. PMID 17650334 DOI: 10.1186/1471-2407-7-135  0.384
2007 Backer MV, Levashova Z, Patel V, Jehning BT, Claffey K, Blankenberg FG, Backer JM. Molecular imaging of VEGF receptors in angiogenic vasculature with single-chain VEGF-based probes. Nature Medicine. 13: 504-9. PMID 17351626 DOI: 10.1038/Nm1522  0.361
2006 Neurath KM, Keough MP, Mikkelsen T, Claffey KP. AMP-dependent protein kinase alpha 2 isoform promotes hypoxia-induced VEGF expression in human glioblastoma. Glia. 53: 733-43. PMID 16518831 DOI: 10.1002/Glia.20326  0.765
2006 Taylor JA, Kuchel GA, Hegde P, Voznesensky OS, Sasso D, Claffey K, Bucala R, Pilbeam C. 634: Mice with a Null Mutation For Macrophage Migration Inhibitory Factor Have Lower Stage Tumors in a Mouse Model of Bladder Cancer Journal of Urology. 175: 204-204. DOI: 10.1016/S0022-5347(18)32880-5  0.349
2005 Backer MV, Gaynutdinov TI, Patel V, Bandyopadhyaya AK, Thirumamagal BT, Tjarks W, Barth RF, Claffey K, Backer JM. Vascular endothelial growth factor selectively targets boronated dendrimers to tumor vasculature. Molecular Cancer Therapeutics. 4: 1423-9. PMID 16170035 DOI: 10.1158/1535-7163.Mct-05-0161  0.473
2005 Belinsky GS, Claffey KP, Nambiar PR, Guda K, Rosenberg DW. Vascular endothelial growth factor and enhanced angiogenesis do not promote metastatic conversion of a newly established azoxymethane-induced colon cancer cell line. Molecular Carcinogenesis. 43: 65-74. PMID 15768385 DOI: 10.1002/Mc.20079  0.395
2004 Murphy M, Carlson JA, Keough MP, Claffey KP, Signoretti S, Loda M. Hypoxia regulation of the cell cycle in malignant melanoma: putative role for the cyclin-dependent kinase inhibitor p27. Journal of Cutaneous Pathology. 31: 477-82. PMID 15239677 DOI: 10.1111/J.0303-6987.2004.00205.X  0.752
2004 Agarwal A, Muñoz-Nájar U, Klueh U, Shih SC, Claffey KP. N-acetyl-cysteine promotes angiostatin production and vascular collapse in an orthotopic model of breast cancer. The American Journal of Pathology. 164: 1683-96. PMID 15111315 DOI: 10.1016/S0002-9440(10)63727-3  0.683
2003 Sanchez T, Estrada-Hernandez T, Paik JH, Wu MT, Venkataraman K, Brinkmann V, Claffey K, Hla T. Phosphorylation and action of the immunomodulator FTY720 inhibits vascular endothelial cell growth factor-induced vascular permeability. The Journal of Biological Chemistry. 278: 47281-90. PMID 12954648 DOI: 10.1074/Jbc.M306896200  0.438
2003 Jang BC, Muñoz-Najar U, Paik JH, Claffey K, Yoshida M, Hla T. Leptomycin B, an inhibitor of the nuclear export receptor CRM1, inhibits COX-2 expression. The Journal of Biological Chemistry. 278: 2773-6. PMID 12468543 DOI: 10.1074/Jbc.C200620200  0.695
2001 Claffey KP, Abrams K, Shih SC, Brown LF, Mullen A, Keough M. Fibroblast growth factor 2 activation of stromal cell vascular endothelial growth factor expression and angiogenesis. Laboratory Investigation; a Journal of Technical Methods and Pathology. 81: 61-75. PMID 11204275 DOI: 10.1038/Labinvest.3780212  0.757
2001 Skobe M, Hawighorst T, Jackson DG, Prevo R, Janes L, Velasco P, Riccardi L, Alitalo K, Claffey K, Detmar M. Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis. Nature Medicine. 7: 192-8. PMID 11175850 DOI: 10.1038/84643  0.492
2000 Zhang JC, Claffey K, Sakthivel R, Darzynkiewicz Z, Shaw DE, Leal J, Wang YC, Lu FM, McCrae KR. Two-chain high molecular weight kininogen induces endothelial cell apoptosis and inhibits angiogenesis: partial activity within domain 5. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 14: 2589-600. PMID 11099478 DOI: 10.1096/Fj.99-1025Com  0.412
2000 Detmar M, Velasco P, Richard L, Claffey KP, Streit M, Riccardi L, Skobe M, Brown LF. Expression of vascular endothelial growth factor induces an invasive phenotype in human squamous cell carcinomas. The American Journal of Pathology. 156: 159-67. PMID 10623663 DOI: 10.1016/S0002-9440(10)64715-3  0.381
1999 Liu XH, Kirschenbaum A, Yao S, Stearns ME, Holland JF, Claffey K, Levine AC. Upregulation of vascular endothelial growth factor by cobalt chloride- simulated hypoxia is mediated by persistent induction of cyclooxygenase-2 in a metastatic human prostate cancer cell line Clinical and Experimental Metastasis. 17: 687-694. PMID 10919714 DOI: 10.1023/A:1006728119549  0.498
1999 Lee MJ, Thangada S, Claffey KP, Ancellin N, Liu CH, Kluk M, Volpi M, Sha'afi RI, Hla T. Vascular endothelial cell adherens junction assembly and morphogenesis induced by sphingosine-1-phosphate. Cell. 99: 301-12. PMID 10555146 DOI: 10.1016/S0092-8674(00)81661-X  0.314
1999 Shih SC, Mullen A, Abrams K, Mukhopadhyay D, Claffey KP. Role of protein kinase C isoforms in phorbol ester-induced vascular endothelial growth factor expression in human glioblastoma cells. The Journal of Biological Chemistry. 274: 15407-14. PMID 10336429 DOI: 10.1074/JBC.274.22.15407  0.399
1998 Pal S, Claffey KP, Cohen HT, Mukhopadhyay D. Activation of Sp1-mediated vascular permeability factor/vascular endothelial growth factor transcription requires specific interaction with protein kinase C zeta. The Journal of Biological Chemistry. 273: 26277-80. PMID 9756852 DOI: 10.1074/JBC.273.41.26277  0.345
1998 Boesiger J, Tsai M, Maurer M, Yamaguchi M, Brown LF, Claffey KP, Dvorak HF, Galli SJ. Mast cells can secrete vascular permeability factor/ vascular endothelial cell growth factor and exhibit enhanced release after immunoglobulin E-dependent upregulation of fc epsilon receptor I expression. The Journal of Experimental Medicine. 188: 1135-45. PMID 9743532 DOI: 10.1084/Jem.188.6.1135  0.319
1998 Claffey KP, Shih SC, Mullen A, Dziennis S, Cusick JL, Abrams KR, Lee SW, Detmar M. Identification of a human VPF/VEGF 3' untranslated region mediating hypoxia-induced mRNA stability Molecular Biology of the Cell. 9: 469-481. PMID 9450968 DOI: 10.1091/Mbc.9.2.469  0.346
1998 Detmar M, Velasco P, Richard L, Claffey K, Brown L. A novel function of vascular endothelial growth factor in tumor progression: Induction of a more malignant tumor phenotype with enhanced infiltration of squamous cell carcinomas Journal of Dermatological Science. 16: S33. DOI: 10.1016/S0923-1811(98)83192-7  0.32
1997 Senger DR, Claffey KP, Benes JE, Perruzzi CA, Sergiou AP, Detmar M. Angiogenesis promoted by vascular endothelial growth factor: regulation through alpha1beta1 and alpha2beta1 integrins. Proceedings of the National Academy of Sciences of the United States of America. 94: 13612-7. PMID 9391074 DOI: 10.1073/Pnas.94.25.13612  0.305
1997 Pal S, Claffey KP, Dvorak HF, Mukhopadhyay D. The von Hippel-Lindau gene product inhibits vascular permeability factor/vascular endothelial growth factor expression in renal cell carcinoma by blocking protein kinase C pathways. The Journal of Biological Chemistry. 272: 27509-12. PMID 9346879 DOI: 10.1074/jbc.272.44.27509  0.382
1997 Provias J, Claffey K, delAguila L, Lau N, Feldkamp M, Guha A. Meningiomas: role of vascular endothelial growth factor/vascular permeability factor in angiogenesis and peritumoral edema. Neurosurgery. 40: 1016-26. PMID 9149260 DOI: 10.1097/00006123-199705000-00027  0.41
1997 Detmar M, Brown LF, Berse B, Jackman RW, Elicker BM, Dvorak HF, Claffey KP. Hypoxia regulates the expression of vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) and its receptors in human skin. The Journal of Investigative Dermatology. 108: 263-8. PMID 9036922 DOI: 10.1111/1523-1747.Ep12286453  0.339
1997 Brown LF, Detmar M, Claffey K, Nagy JA, Feng D, Dvorak AM, Dvorak HF. Vascular permeability factor/vascular endothelial growth factor: a multifunctional angiogenic cytokine. Exs. 79: 233-69. PMID 9002222 DOI: 10.1007/978-3-0348-9006-9_10  0.308
1996 Claffey KP, Robinson GS. Regulation of VEGF/VPF expression in tumor cells: Consequences for tumor growth and metastasis Cancer and Metastasis Reviews. 15: 165-176. PMID 8842488 DOI: 10.1007/BF00437469  0.404
1995 Dvorak HF, Detmar M, Claffey KP, Nagy JA, van de Water L, Senger DR. Vascular permeability factor/vascular endothelial growth factor: an important mediator of angiogenesis in malignancy and inflammation. International Archives of Allergy and Immunology. 107: 233-5. PMID 7542074 DOI: 10.1159/000236988  0.321
1994 Detmar M, Brown LF, Claffey KP, Yeo KT, Kocher O, Jackman RW, Berse B, Dvorak HF. Overexpression of vascular permeability factor/vascular endothelial growth factor and its receptors in psoriasis Journal of Experimental Medicine. 180: 1141-1146. PMID 8064230 DOI: 10.1084/Jem.180.3.1141  0.312
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