Sergei N. Orlov - Publications

Affiliations: 
Université de Montréal, Montréal, Canada 
Area:
Animal Physiology Biology, Cell Biology

209 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Orlov SN, Tverskoi AM, Sidorenko SV, Smolyaninova LV, Lopina OD, Dulin NO, Klimanova EA. Na,K-ATPase as a target for endogenous cardiotonic steroids: What's the evidence? Genes & Diseases. 8: 259-271. PMID 33997173 DOI: 10.1016/j.gendis.2020.01.008  0.372
2020 Klimanova EA, Sidorenko SV, Abramicheva PA, Tverskoi AM, Orlov SN, Lopina OD. Transcriptomic Changes in Endothelial Cells Triggered by Na,K-ATPase Inhibition: A Search for Upstream Na/K Sensitive Genes. International Journal of Molecular Sciences. 21. PMID 33121152 DOI: 10.3390/ijms21217992  0.383
2020 Lopina OD, Tverskoi AM, Klimanova EA, Sidorenko SV, Orlov SN. Ouabain-Induced Cell Death and Survival. Role of α1-Na,K-ATPase-Mediated Signaling and [Na]/[K]-Dependent Gene Expression. Frontiers in Physiology. 11: 1060. PMID 33013454 DOI: 10.3389/fphys.2020.01060  0.414
2020 Klimanova EA, Fedorov DA, Sidorenko SV, Abramicheva PA, Lopina OD, Orlov SN. Ouabain and Marinobufagenin: Physiological Effects on Human Epithelial and Endothelial Cells. Biochemistry. Biokhimiia. 85: 507-515. PMID 32569558 DOI: 10.1134/S0006297920040112  0.507
2020 Lopina OD, Tverskoi AM, Klimanova EA, Sidorenko SV, Orlov SN. Ouabain-Induced Cell Death and Survival. Role of α1-Na,K-ATPase-Mediated Signaling and [Na+]i/[K+]i-Dependent Gene Expression Frontiers in Physiology. 11. DOI: 10.3389/Fphys.2020.01060  0.501
2020 Tverskoi AM, Lokteva VA, Orlov SN, Lopina OD. Binding of Ouabain, Digoxin, or Marinobufagenin Induces Different Conformational Changes in Kidney α1-Na+,K+-ATPase Isoforms, Resistant and Sensitive to Cardiotonic Steroids Biochemistry (Moscow), Supplement Series a: Membrane and Cell Biology. 14: 54-60. DOI: 10.1134/S1990747820010080  0.424
2020 Orlov SN, Tverskoi AM, Sidorenko SV, Smolyaninova LV, Lopina OD, Dulin NO, Klimanova EA. Na,K-ATPase as a target for endogenous cardiotonic steroids: What's the evidence? Genes and Diseases. DOI: 10.1016/J.Gendis.2020.01.008  0.474
2019 Klimanova EA, Sidorenko SV, Tverskoi AM, Shiyan AA, Smolyaninova LV, Kapilevich LV, Gusakova SV, Maksimov GV, Lopina OD, Orlov SN. Search for Intracellular Sensors Involved in the Functioning of Monovalent Cations as Secondary Messengers. Biochemistry. Biokhimiia. 84: 1280-1295. PMID 31760918 DOI: 10.1134/S0006297919110063  0.423
2019 Smolyaninova LV, Shiyan AA, Kapilevich LV, Lopachev AV, Fedorova TN, Klementieva TS, Moskovtsev AA, Kubatiev AA, Orlov SN. Transcriptomic changes triggered by ouabain in rat cerebellum granule cells: Role of α3- and α1-Na+,K+-ATPase-mediated signaling. Plos One. 14: e0222767. PMID 31557202 DOI: 10.1371/Journal.Pone.0222767  0.452
2019 Shiyan AA, Sidorenko SV, Fedorov D, Klimanova EA, Smolyaninova LV, Kapilevich LV, Grygorczyk R, Orlov SN. Elevation of Intracellular Na Contributes to Expression of Early Response Genes Triggered by Endothelial Cell Shrinkage. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 53: 638-647. PMID 31556253 DOI: 10.33594/000000162  0.426
2019 Dulin NO, Smolyaninova LV, Orlov SN. Control of lung myofibroblast transformation by monovalent ion transporters. Current Topics in Membranes. 83: 15-43. PMID 31196603 DOI: 10.1016/Bs.Ctm.2019.01.002  0.457
2019 Klimanova EA, Sidorenko SV, Smolyaninova LV, Kapilevich LV, Gusakova SV, Lopina OD, Orlov SN. Ubiquitous and cell type-specific transcriptomic changes triggered by dissipation of monovalent cation gradients in rodent cells: Physiological and pathophysiological implications. Current Topics in Membranes. 83: 107-149. PMID 31196602 DOI: 10.1016/Bs.Ctm.2019.01.006  0.429
2019 Smolyaninova LV, Shiyan AA, Klementieva TS, Moskovtsev AA, Kubatiev AA, Orlov SN. Ouabain at Low Concentrations Affects Transcription without Any Impact on Intracellular Content of Sodium and Potassium in Rat Brain Neurons Biochemistry (Moscow), Supplement Series a: Membrane and Cell Biology. 13: 365-371. DOI: 10.1134/S1990747819030073  0.465
2018 Sidorenko S, Klimanova E, Milovanova K, Lopina OD, Kapilevich LV, Chibalin AV, Orlov SN. Transcriptomic changes in C2C12 myotubes triggered by electrical stimulation: Role of Ca-mediated and Ca-independent signaling and elevated [Na]/[K] ratio. Cell Calcium. 76: 72-86. PMID 30300758 DOI: 10.1016/J.Ceca.2018.09.007  0.429
2018 Orlov SN, Shiyan A, Boudreault F, Ponomarchuk O, Grygorczyk R. Search for Upstream Cell Volume Sensors: The Role of Plasma Membrane and Cytoplasmic Hydrogel. Current Topics in Membranes. 81: 53-82. PMID 30243440 DOI: 10.1016/Bs.Ctm.2018.07.001  0.409
2018 Sidorenko SV, Luneva OG, Novozhilova TS, Alekseeva NV, Rodnenkov OV, Deev LI, Maksimov GV, Grygorczyk R, Orlov SN. Hemolysis and ATP Release from Human and Rat Erythrocytes under Conditions of Hypoxia: A Comparative Study Biochemistry (Moscow), Supplement Series a: Membrane and Cell Biology. 12: 114-120. DOI: 10.1134/S1990747818020125  0.353
2018 Ponomarchuk OO, Boudreault F, Shiyan AA, Maksimov GV, Grygorczyk R, Orlov SN. A Method to Simultaneously Detect Changes in Intracellular Ca2+ Concentration and Cell Volume Biophysics. 63: 369-374. DOI: 10.1134/S000635091803020X  0.346
2018 Orlov SN, Koltsova S, Sidorenko S, Smolyaninova L. INTRACELLULAR MONOVALENT CATIONS AS REGULATOR OF GENE EXPRESSION: ROLE OF Ca2+i-MEDIATED AND -INDEPENDENT SIGNALING Pathophysiology. 25: 161. DOI: 10.1016/J.Pathophys.2018.07.009  0.304
2017 Orlov SN, Gusakova SV, Smaglii LV, Koltsova SV, Sidorenko SV. Vasoconstriction triggered by hydrogen sulfide: Evidence for Na(+),K(+),2Cl(-)cotransport and L-type Ca(2+) channel-mediated pathway. Biochemistry and Biophysics Reports. 12: 220-227. PMID 29159314 DOI: 10.1016/J.Bbrep.2017.09.010  0.432
2017 Smolyaninova LV, Koltsova SV, Sidorenko SV, Orlov SN. Augmented gene expression triggered by Na(+),K(+)-ATPase inhibition: Role of Ca(2+)i-mediated and -independent excitation-transcription coupling. Cell Calcium. 68: 5-13. PMID 29129208 DOI: 10.1016/J.Ceca.2017.10.002  0.427
2017 Danilov K, Sidorenko S, Milovanova K, Klimanova E, Kapilevich LV, Orlov SN. Electrical pulse stimulation decreases electrochemical Na(+) and K(+) gradients in C2C12 myotubes. Biochemical and Biophysical Research Communications. PMID 28958945 DOI: 10.1016/J.Bbrc.2017.09.133  0.466
2017 Orlov SN, La J, Smolyaninova LV, Dulin NO. Na+,K+-ATPase as a target for treatment of tissue fibrosis. Current Medicinal Chemistry. PMID 28625151 DOI: 10.2174/0929867324666170619105407  0.426
2017 Orlov SN, Klimanova EA, Tverskoi AM, Vladychenskaya EA, Smolyaninova LV, Lopina OD. Na⁺i,K⁺i-Dependent and -Independent Signaling Triggered by Cardiotonic Steroids: Facts and Artifacts. Molecules (Basel, Switzerland). 22. PMID 28420099 DOI: 10.3390/Molecules22040635  0.309
2017 Klimanova EA, Tverskoi AM, Koltsova SV, Sidorenko SV, Lopina OD, Tremblay J, Hamet P, Kapilevich LV, Orlov SN. Time- and dose dependent actions of cardiotonic steroids on transcriptome and intracellular content of Na(+) and K(+): a comparative analysis. Scientific Reports. 7: 45403. PMID 28345607 DOI: 10.1038/Srep45403  0.473
2017 Akimova OA, Kapilevich LV, Orlov SN, Lopina OD. Identification of Proteins Whose Interaction with Na+,K+-ATPase Is Triggered by Ouabain. Biochemistry. Biokhimiia. 81: 1013-22. PMID 27682173 DOI: 10.1134/S0006297916090108  0.471
2017 Tverskoi AM, Sidorenko SV, Klimanova EA, Akimova OA, Smolyaninova LV, Lopina OD, Orlov SN. Effects of Ouabain on Proliferation of Human Endothelial Cells Correlate with Na+,K+-ATPase Activity and Intracellular Ratio of Na+ and K. Biochemistry. Biokhimiia. 81: 876-83. PMID 27677555 DOI: 10.1134/S0006297916080083  0.509
2017 Gusakova SV, Kovalev IV, Birulina YG, Smagliy LV, Petrova IV, Nosarev AV, Aleinyk AN, Orlov SN. The effects of carbon monoxide and hydrogen sulfide on transmembrane ion transport Biophysics. 62: 220-226. DOI: 10.1134/S0006350917020099  0.34
2017 Ponomarchuk O, Boudreault F, Orlov SN, Grygorczyk R. Mechanosensetive ATP Release Involves a Non-Conductive Pathway: Evidence from Large Field of View Real-Time Imaging Biophysical Journal. 112: 311a. DOI: 10.1016/J.Bpj.2016.11.1684  0.354
2016 La J, Reed E, Chan L, Smolyaninova LV, Akomova OA, Mutlu GM, Orlov SN, Dulin NO. Downregulation of TGF-β Receptor-2 Expression and Signaling through Inhibition of Na/K-ATPase. Plos One. 11: e0168363. PMID 28006004 DOI: 10.1371/Journal.Pone.0168363  0.4
2016 Gusakova SV, Birulina YG, Smagliy LV, Kovalev IV, Petrova IV, Nosarev AV, Orlov SN. Regulation of Contractile Responses of Vascular Smooth Muscle Cells under Conditions of Hypoxia-Reoxygenation. Bulletin of Experimental Biology and Medicine. PMID 27913935 DOI: 10.1007/s10517-016-3574-0  0.325
2016 Ponomarchuk O, Boudreault F, Orlov SN, Grygorczyk R. Calcium is not required for triggering volume restoration in hypotonically challenged A549 epithelial cells. Pflugers Archiv : European Journal of Physiology. PMID 27796579 DOI: 10.1007/S00424-016-1896-4  0.371
2016 Luneva OG, Sidorenko SV, Ponomarchuk OO, Tverskoy AM, Cherkashin AA, Rodnenkov OV, Alekseeva NV, Deev LI, Maksimov GV, Grygorczyk R, Orlov SN. Deoxygenation Affects Composition of Membrane-Bound Proteins in Human Erythrocytes. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 39: 81-88. PMID 27322642 DOI: 10.1159/000445607  0.307
2016 La J, Reed EB, Koltsova SV, Akimova O, Hamanaka RB, Mutlu GM, Orlov SN, Dulin NO. Regulation of myofibroblast differentiation by cardiac glycosides. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00322.2015. PMID 26851261 DOI: 10.1152/Ajplung.00322.2015  0.46
2015 Kapilevich LV, Kironenko TA, Zaharova AN, Kotelevtsev YV, Dulin NO, Orlov SN. Skeletal muscle as an endocrine organ: Role of [Na(+)]i/[K(+)]i-mediated excitation-transcription coupling. Genes & Diseases. 2: 328-336. PMID 27610402 DOI: 10.1016/J.Gendis.2015.10.001  0.45
2015 Koltsova SV, Tremblay J, Hamet P, Orlov SN. Transcriptomic changes in Ca(2+)-depleted cells: Role of elevated intracellular [Na(+)]/[K(+)] ratio. Cell Calcium. PMID 26183762 DOI: 10.1016/J.Ceca.2015.06.009  0.479
2015 Platonova A, Ponomarchuk O, Boudreault F, Kapilevich LV, Maksimov GV, Grygorczyk R, Orlov SN. Role of cytoskeleton network in anisosmotic volume changes of intact and permeabilized A549 cells. Biochimica Et Biophysica Acta. 1848: 2337-43. PMID 26171817 DOI: 10.1016/J.Bbamem.2015.07.005  0.42
2015 Orlov SN, Koltsova SV, Kapilevich LV, Gusakova SV, Dulin NO. NKCC1 and NKCC2: The pathogenetic role of cation-chloride cotransporters in hypertension. Genes & Diseases. 2: 186-196. PMID 26114157 DOI: 10.1016/J.Gendis.2015.02.007  0.35
2015 Akimova OA, Tverskoi AM, Smolyaninova LV, Mongin AA, Lopina OD, La J, Dulin NO, Orlov SN. Critical role of the α1-Na(+), K(+)-ATPase subunit in insensitivity of rodent cells to cytotoxic action of ouabain. Apoptosis : An International Journal On Programmed Cell Death. 20: 1200-10. PMID 26067145 DOI: 10.1007/S10495-015-1144-Y  0.503
2015 Orlov SN, Koltsova SV, Kapilevich LV, Dulin NO, Gusakova SV. Cation-chloride cotransporters: regulation, physiological significance, and role in pathogenesis of arterial hypertension. Biochemistry. Biokhimiia. 79: 1546-61. PMID 25749164 DOI: 10.1134/S0006297914130070  0.462
2015 Grygorczyk R, Boudreault F, Platonova A, Orlov SN. Salt and osmosensing: role of cytoplasmic hydrogel. PflüGers Archiv : European Journal of Physiology. 467: 475-87. PMID 25564208 DOI: 10.1007/S00424-014-1680-2  0.338
2015 Orlov SN, Hamet P. Salt and gene expression: evidence for [Na+]i/[K+]i-mediated signaling pathways. PflüGers Archiv : European Journal of Physiology. 467: 489-98. PMID 25479826 DOI: 10.1007/S00424-014-1650-8  0.493
2015 Luneva OG, Sidorenko SV, Maksimov GV, Grygorczyk R, Orlov SN. Erythrocytes as regulators of blood vessel tone Biochemistry (Moscow) Supplement Series a: Membrane and Cell Biology. 9: 161-171. DOI: 10.1134/S1990747815040078  0.302
2015 Smaglii L, Gusakova S, Birulina J, Kovalev I, Orlov S. Pp.42.17: Role Of Nkcc In Contractile Action Of Hydrogen Sulfide On Vascular Smooth Muscle Cells Journal of Hypertension. 33. DOI: 10.1097/01.Hjh.0000469010.71503.Ee  0.335
2014 Koltsova SV, Shilov B, Birulina JG, Akimova OA, Haloui M, Kapilevich LV, Gusakova SV, Tremblay J, Hamet P, Orlov SN. Transcriptomic changes triggered by hypoxia: evidence for HIF-1α-independent, [Na+]i/[K+]i-mediated, excitation-transcription coupling. Plos One. 9: e110597. PMID 25375852 DOI: 10.1371/Journal.Pone.0110597  0.476
2014 Sikora J, Orlov SN, Furuya K, Grygorczyk R. Hemolysis is a primary ATP-release mechanism in human erythrocytes. Blood. 124: 2150-7. PMID 25097178 DOI: 10.1182/Blood-2014-05-572024  0.306
2014 Platonova A, Boudreault F, Kapilevich LV, Maksimov GV, Ponomarchuk O, Grygorczyk R, Orlov SN. Temperature-induced inactivation of cytoplasmic biogel osmosensing properties is associated with suppression of regulatory volume decrease in A549 cells. The Journal of Membrane Biology. 247: 571-9. PMID 24840161 DOI: 10.1007/S00232-014-9673-9  0.38
2014 Kach J, Sandbo N, La J, Denner D, Reed EB, Akimova O, Koltsova S, Orlov SN, Dulin NO. Antifibrotic effects of noscapine through activation of prostaglandin E2 receptors and protein kinase A. The Journal of Biological Chemistry. 289: 7505-13. PMID 24492608 DOI: 10.1074/Jbc.M113.546812  0.308
2014 Orlov SN, Koltsova SV, Anfinogenova YD, Kapilevich LV, Gusakova SN, Smagliy LV, Baskakov MB, Medvedev MA. SODIUM-POTASSIUM-CHLORIDE COTRANSPORT IN THE REGULATION OF VASCULAR MYOGENIC TONE Bulletin of Siberian Medicine. 13: 165-173. DOI: 10.20538/1682-0363-2014-6-165-173  0.371
2013 Orlov SN, Model MA, Grygorczyk R. Rebuttal from Sergei N. Orlov, Michael M. Model and Ryszard Grygorczyk. The Journal of Physiology. 591: 6129. PMID 24339148 DOI: 10.1113/Jphysiol.2013.265264  0.384
2013 Orlov SN, Model MA, Grygorczyk R. CrossTalk opposing view: The triggering and progression of the cell death machinery can occur without cell volume perturbations. The Journal of Physiology. 591: 6123-5. PMID 24339146 DOI: 10.1113/Jphysiol.2013.258624  0.336
2013 Haloui M, Tremblay J, Seda O, Koltsova SV, Maksimov GV, Orlov SN, Hamet P. Increased renal epithelial na channel expression and activity correlate with elevation of blood pressure in spontaneously hypertensive rats. Hypertension. 62: 731-7. PMID 23959560 DOI: 10.1161/Hypertensionaha.113.01295  0.337
2013 Orlov SN, Platonova AA, Hamet P, Grygorczyk R. Cell volume and monovalent ion transporters: their role in cell death machinery triggering and progression. American Journal of Physiology. Cell Physiology. 305: C361-72. PMID 23615964 DOI: 10.1152/Ajpcell.00040.2013  0.52
2013 Parshina EY, Yusipovich AI, Platonova AA, Grygorczyk R, Maksimov GV, Orlov SN. Thermal inactivation of volume-sensitive K⁺,Cl⁻ cotransport and plasma membrane relief changes in human erythrocytes. Pflugers Archiv : European Journal of Physiology. 465: 977-83. PMID 23377567 DOI: 10.1007/S00424-013-1221-4  0.345
2013 Platonova AA, Koltsova SV, Maksimov GV, Grygorszyk R, Orlov SN. 3-Dimensional microscopy as a method for volume measurement in cells undergoing apoptosis Biophysics. 58: 389-393. DOI: 10.1134/S0006350913030135  0.383
2012 Orlov SN, Koltsova SV, Tremblay J, Baskakov MB, Hamet P. NKCC1 and hypertension: role in the regulation of vascular smooth muscle contractions and myogenic tone. Annals of Medicine. 44: S111-8. PMID 22713139 DOI: 10.3109/07853890.2011.653395  0.389
2012 Koltsova SV, Trushina Y, Haloui M, Akimova OA, Tremblay J, Hamet P, Orlov SN. Ubiquitous [Na+]i/[K+]i-sensitive transcriptome in mammalian cells: evidence for Ca(2+)i-independent excitation-transcription coupling. Plos One. 7: e38032. PMID 22666440 DOI: 10.1371/Journal.Pone.0038032  0.479
2012 Koltsova SV, Akimova OA, Kotelevtsev SV, Grygorczyk R, Orlov SN. Hyperosmotic and isosmotic shrinkage differentially affect protein phosphorylation and ion transport. Canadian Journal of Physiology and Pharmacology. 90: 209-17. PMID 22300272 DOI: 10.1139/Y11-119  0.493
2012 Platonova A, Koltsova SV, Hamet P, Grygorczyk R, Orlov SN. Swelling rather than shrinkage precedes apoptosis in serum-deprived vascular smooth muscle cells. Apoptosis : An International Journal On Programmed Cell Death. 17: 429-38. PMID 22249286 DOI: 10.1007/S10495-011-0694-X  0.447
2012 Akimova OA, Van Huysse J, Tremblay J, Orlov SN. Low efficiency of functional translation of ouabain-resistant α2-Na(+),K(+)-ATPase mRNA in C7-MDCK epithelial cells. Canadian Journal of Physiology and Pharmacology. 90: 83-8. PMID 22188474 DOI: 10.1139/Y11-113  0.486
2011 Platonova A, Koltsova S, Maksimov GV, Grygorczyk R, Orlov SN. The death of ouabain-treated renal epithelial C11-MDCK cells is not mediated by swelling-induced plasma membrane rupture. The Journal of Membrane Biology. 241: 145-54. PMID 21584679 DOI: 10.1007/S00232-011-9371-9  0.411
2011 Koltsova SV, Platonova A, Maksimov GV, Mongin AA, Grygorczyk R, Orlov SN. Activation of P2Y receptors causes strong and persistent shrinkage of C11-MDCK renal epithelial cells. American Journal of Physiology. Cell Physiology. 301: C403-12. PMID 21562307 DOI: 10.1152/Ajpcell.00018.2011  0.44
2011 Koltsova SV, Trushina YA, Akimova OA, Hamet P, Orlov SN. Molecular origin of Na(+)/Li(+) exchanger: Evidence against the involvement of major cloned erythrocyte transporters. Pathophysiology : the Official Journal of the International Society For Pathophysiology / Isp. 18: 207-13. PMID 21247741 DOI: 10.1016/J.Pathophys.2010.12.001  0.417
2011 Baskakov M, Gusakova S, Zheludeva A, Smagly L, Kovalev I, Medvedev M, Orlov S. MECHANISMS OF ACTION OF HYDROGEN SULFIDE ON CONTRACTILE ACTIVITY VASCULAR SMOOTH MUSCLE Journal of Hypertension. 29: e335. DOI: 10.1097/00004872-201106001-00966  0.3
2011 Kovalev I, Gusakova S, Baskakov M, Popov A, Melnik O, Vtorushina T, Nosov D, Zheludeva A, Smagliy L, Medvedev M, Orlov S. EFFECT OF HYDROGEN SULFIDE ON MECHANISMS COUPLING EXCITATION OF SMOOTH MUSCLE CELLS GUINEA PIG URETER Journal of Hypertension. 29: e334-e335. DOI: 10.1097/00004872-201106001-00965  0.31
2010 Akimova OA, Lopina OD, Rubtsov AM, Hamet P, Orlov SN. Investigation of mechanism of p38 MAPK activation in renal epithelial cell from distal tubules triggered by cardiotonic steroids. Biochemistry. 75: 971-978. PMID 21073417 DOI: 10.1134/S0006297910080043  0.497
2010 Orlov SN, Tremblay J, Hamet P. NKCC1 and hypertension: a novel therapeutic target involved in the regulation of vascular tone and renal function. Current Opinion in Nephrology and Hypertension. 19: 163-8. PMID 20061948 DOI: 10.1097/Mnh.0B013E3283360A46  0.38
2010 Orlov SN, Gossard F, Pausova Z, Akimova OA, Tremblay J, Grim CE, Kotchen JM, Kotchen TA, Gaudet D, Cowley AW, Hamet P. Decreased NKCC1 activity in erythrocytes from African Americans with hypertension and dyslipidemia. American Journal of Hypertension. 23: 321-6. PMID 20044742 DOI: 10.1038/Ajh.2009.249  0.308
2010 Akimova OA, Tremblay J, Van Huysse JW, Hamet P, Orlov SN. Cardiotonic steroid-resistant alpha1-Na+,K+-ATPase rescues renal epithelial cells from the cytotoxic action of ouabain: evidence for a Nai+,Ki+ -independent mechanism. Apoptosis : An International Journal On Programmed Cell Death. 15: 55-62. PMID 19949978 DOI: 10.1007/S10495-009-0429-4  0.501
2010 Koltsova SV, Аkimova ОА, Kotelevtsev SV, Hamet P., Orlov SN. Increased Na+/Li+ exchange in erythrocytes of patients with essential hypertension is not caused by activation of Na+,Pi cotransport "Arterial’Naya Gipertenziya" ("Arterial Hypertension"). 16: 385-389. DOI: 10.18705/1607-419X-2010-16-4-385-389  0.41
2010 Kovalev I, Gusakova S, Baskakov M, Popov A, Melnik O, Vtorushina T, Nosov D, Zheludeva A, Medvedev M, Orlov S. Effect Of Reactive Oxygen On Mechanisms Coupling Excitation Of Smooth Muscle Cells Guinea Pig Ureter: Pp.21.345 Journal of Hypertension. 28. DOI: 10.1097/01.Hjh.0000379271.69819.68  0.305
2010 Gusakova S, Baskakov M, Kovalev I, Popov A, Melnik O, Zheludeva A, Medvedev M, Orlov S. Regulation Of Contractile Activity Of Smooth Muscle Cells By Reactive Oxygen Species: Evidence For Cytoskeleton-Mediated Signaling: Pp.21.344 Journal of Hypertension. 28. DOI: 10.1097/01.Hjh.0000379270.92689.14  0.324
2009 Akimova OA, Lopina OD, Rubtsov AM, Gekle M, Tremblay J, Hamet P, Orlov SN. Death of ouabain-treated renal epithelial cells: evidence for p38 MAPK-mediated Na (i) (+) /K (i) (+) -independent signaling. Apoptosis : An International Journal On Programmed Cell Death. 14: 1266-73. PMID 19784777 DOI: 10.1007/S10495-009-0404-0  0.513
2009 Koltsova SV, Luneva OG, Lavoie JL, Tremblay J, Maksimov GV, Hamet P, Orlov SN. HCO3-dependent impact of Na+,K+,2Cl- cotransport in vascular smooth muscle excitation-contraction coupling. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 23: 407-14. PMID 19471108 DOI: 10.1159/000218187  0.464
2009 Koltsova SV, Maximov GV, Kotelevtsev SV, Lavoie JL, Tremblay J, Grygorczyk R, Hamet P, Orlov SN. Myogenic tone in mouse mesenteric arteries: evidence for P2Y receptor-mediated, Na(+), K (+), 2Cl (-) cotransport-dependent signaling. Purinergic Signalling. 5: 343-9. PMID 19387869 DOI: 10.1007/S11302-009-9160-4  0.374
2009 Koltsova SV, Kotelevtsev SV, Tremblay J, Hamet P, Orlov SN. Excitation-contraction coupling in resistance mesenteric arteries: evidence for NKCC1-mediated pathway. Biochemical and Biophysical Research Communications. 379: 1080-3. PMID 19150334 DOI: 10.1016/J.Bbrc.2009.01.018  0.403
2008 Akimova OA, Lopina OD, Tremblay J, Hamet P, Orlov SN. Altered phosphorylation of RRXS*/T* motif in ouabain-treated renal epithelial cells is not mediated by inversion of the [Na](i)/[K+](i) ratio. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 21: 315-24. PMID 18441520 DOI: 10.1159/000129390  0.5
2008 Akimova OA, Poirier M, Kotelevtsev SV, Hamet P, Orlov SN. The death of ouabain-treated renal epithelial cells: evidence against anoikis occurrence. Apoptosis : An International Journal On Programmed Cell Death. 13: 670-80. PMID 18392681 DOI: 10.1007/S10495-008-0204-Y  0.491
2008 Akimova OA, Taurin S, Dulin NO, Orlov SN. Purinergic inhibition of Na⁺,K⁺,Cl⁻ cotransport in C11-MDCK cells: Role of stress-activated protein kinases. Purinergic Signalling. 4: 183-91. PMID 18368525 DOI: 10.1007/S11302-007-9057-Z  0.657
2008 Koltsova SV, Gusakova SV, Anfinogenova YJ, Baskakov MB, Orlov SN. Vascular smooth muscle contraction evoked by cell volume modulation: role of the cytoskeleton network. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 21: 29-36. PMID 18209469 DOI: 10.1159/000113744  0.363
2008 Akimova OA, Hamet P, Orlov SN. [Na+]i/[K+]i -independent death of ouabain-treated renal epithelial cells is not mediated by Na+,K+ -ATPase internalization and de novo gene expression. PflüGers Archiv : European Journal of Physiology. 455: 711-9. PMID 17622553 DOI: 10.1007/S00424-007-0283-6  0.511
2007 Orlov SN. On the history of ecto-ATPases: The role of W. A. Engelhardt. Purinergic Signalling. 3: 231-2. PMID 18404436 DOI: 10.1007/S11302-007-9055-1  0.376
2007 Postnov YV, Orlov SN, Budnikov YY, Doroschuk AD, Postnov AY. Mitochondrial energy conversion disturbance with decrease in ATP production as a source of systemic arterial hypertension. Pathophysiology : the Official Journal of the International Society For Pathophysiology / Isp. 14: 195-204. PMID 17949954 DOI: 10.1016/J.Pathophys.2007.09.002  0.304
2007 Dolgova NV, Kamanina IuV, Akimova OA, Orlov SN, Rubtsov AM, Lopina OD. A protein whose binding to Na,K-ATPase is regulated by ouabain. Biochemistry. Biokhimiia. 72: 863-71. PMID 17922644 DOI: 10.1134/S0006297907080081  0.386
2007 Tatur S, Groulx N, Orlov SN, Grygorczyk R. Ca2+-dependent ATP release from A549 cells involves synergistic autocrine stimulation by coreleased uridine nucleotides. The Journal of Physiology. 584: 419-35. PMID 17702822 DOI: 10.1113/Jphysiol.2007.133314  0.321
2007 Orlov SN, Mongin AA. Salt-sensing mechanisms in blood pressure regulation and hypertension. American Journal of Physiology. Heart and Circulatory Physiology. 293: H2039-53. PMID 17693546 DOI: 10.1152/Ajpheart.00325.2007  0.392
2007 Haloui M, Taurin S, Akimova OA, Guo DF, Tremblay J, Dulin NO, Hamet P, Orlov SN. [Na]i -induced c-Fos expression is not mediated by activation of the 5' -promoter containing known transcriptional elements. The Febs Journal. 274: 3557-67. PMID 17565602 DOI: 10.1111/J.1742-4658.2007.05885.X  0.719
2007 Luneva OG, Brazhe NA, Maksimova NV, Rodnenkov OV, Parshina EY, Bryzgalova NY, Maksimov GV, Rubin AB, Orlov SN, Chazov EI. Ion transport, membrane fluidity and haemoglobin conformation in erythrocyte from patients with cardiovascular diseases: Role of augmented plasma cholesterol. Pathophysiology : the Official Journal of the International Society For Pathophysiology. 14: 41-6. PMID 17403600 DOI: 10.1016/J.Pathophys.2006.12.001  0.331
2007 Orlov SN. NKCC1 as a regulator of vascular tone and a novel target for antihypertensive therapeutics. American Journal of Physiology. Heart and Circulatory Physiology. 292: H2035-6. PMID 17308011 DOI: 10.1152/Ajpheart.00157.2007  0.477
2007 Orlov SN, Hamet P. The death of cardiotonic steroid-treated cells: evidence of Na+i,K+i-independent H+i-sensitive signalling. Acta Physiologica (Oxford, England). 187: 231-40. PMID 16734760 DOI: 10.1111/J.1748-1716.2006.01546.X  0.513
2007 Akimova OA, Hamet P, Orlov SN. Proteomic‐based identification of upstream intermediates of Na+i,K+i‐independent death signaling triggered by interaction of cardiotonic steroids with alpha‐subunit of Na,K‐ATPase The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A534  0.44
2006 Groulx N, Boudreault F, Orlov SN, Grygorczyk R. Membrane reserves and hypotonic cell swelling. The Journal of Membrane Biology. 214: 43-56. PMID 17598067 DOI: 10.1007/S00232-006-0080-8  0.318
2006 Akimova OA, Grygorczyk A, Bundey RA, Bourcier N, Gekle M, Insel PA, Orlov SN. Transient activation and delayed inhibition of Na+,K+,Cl- cotransport in ATP-treated C11-MDCK cells involve distinct P2Y receptor subtypes and signaling mechanisms. The Journal of Biological Chemistry. 281: 31317-25. PMID 16916802 DOI: 10.1074/Jbc.M602117200  0.419
2006 Orlov SN, Hamet P. Intracellular monovalent ions as second messengers. The Journal of Membrane Biology. 210: 161-72. PMID 16909338 DOI: 10.1007/S00232-006-0857-9  0.344
2006 Akimova O, Tremblay J, Hamet P, Orlov SN. The Na(+)/K(+)-ATPase as [K(+)](o) sensor: Role in cardiovascular disease pathogenesis and augmented production of endogenous cardiotonic steroids. Pathophysiology : the Official Journal of the International Society For Pathophysiology / Isp. 13: 209-16. PMID 16857351 DOI: 10.1016/J.Pathophys.2006.06.001  0.446
2006 Akimova OA, Pchejetski D, Hamet P, Orlov SN. Modest intracellular acidification suppresses death signaling in ouabain-treated cells. PflüGers Archiv : European Journal of Physiology. 451: 569-78. PMID 16052351 DOI: 10.1007/S00424-005-1493-4  0.536
2005 Orlov SN. Decreased Na+,K+,2Cl- cotransport and salt retention in Blacks: a provocative hypothesis. Journal of Hypertension. 23: 1929-30. PMID 16148618 DOI: 10.1097/01.Hjh.0000181324.51786.29  0.439
2005 Akimova AO, Bourcier N, Taurin S, Bundey RA, Grygorczyk K, Gekle M, Insel PA, Dulin NO, Orlov SN. Cl- secretion in ATP-treated renal epithelial C7-MDCK cells is mediated by activation of P 2Y1 receptors, phospholipase A2 and protein kinase A. The Journal of Physiology. 568: 789-801. PMID 16109726 DOI: 10.1113/Jphysiol.2005.094375  0.671
2005 Akimova OA, Lopina OD, Hamet P, Orlov SN. Search for intermediates of Na+,K+-ATPase-mediated [Na+]i/[K+]i-independent death signaling triggered by cardiotonic steroids. Pathophysiology : the Official Journal of the International Society For Pathophysiology / Isp. 12: 125-35. PMID 16023561 DOI: 10.1016/J.Pathophys.2005.03.003  0.501
2005 Orlov SN, Aksentsev SL, Kotelevtsev SV. Extracellular calcium is required for the maintenance of plasma membrane integrity in nucleated cells. Cell Calcium. 38: 53-7. PMID 15936814 DOI: 10.1016/J.Ceca.2005.03.006  0.366
2005 Akimova OA, Bagrov AY, Lopina OD, Kamernitsky AV, Tremblay J, Hamet P, Orlov SN. Cardiotonic steroids differentially affect intracellular Na+ and [Na+]i/[K+]i-independent signaling in C7-MDCK cells. The Journal of Biological Chemistry. 280: 832-9. PMID 15494417 DOI: 10.1074/Jbc.M411011200  0.514
2005 Orlov S, Akimova O, Hamet P. Cardiotonic Steroids: Novel Mechanisms of Na+ i-Mediated and - Independent Signaling Involved in the Regulation of Gene Expression, Proliferation and Cell Death Current Hypertension Reviews. 1: 243-257. DOI: 10.2174/157340205774574559  0.496
2004 Orlov SN, Hamet P. Apoptosis vs. oncosis: role of cell volume and intracellular monovalent cations. Advances in Experimental Medicine and Biology. 559: 219-33. PMID 18727243 DOI: 10.1007/0-387-23752-6_21  0.543
2004 Anfinogenova YJ, Baskakov MB, Kovalev IV, Kilin AA, Dulin NO, Orlov SN. Cell-volume-dependent vascular smooth muscle contraction: role of Na+, K+, 2Cl- cotransport, intracellular Cl- and L-type Ca2+ channels. PflüGers Archiv : European Journal of Physiology. 449: 42-55. PMID 15293051 DOI: 10.1007/S00424-004-1316-Z  0.494
2004 Orlov SN, Thorin-Trescases N, Pchejetski D, Taurin S, Farhat N, Tremblay J, Thorin E, Hamet P. Na+/K+ pump and endothelial cell survival: [Na+]i/[K+]i-independent necrosis triggered by ouabain, and protection against apoptosis mediated by elevation of [Na+]i. PflüGers Archiv : European Journal of Physiology. 448: 335-45. PMID 15069561 DOI: 10.1007/S00424-004-1262-9  0.736
2004 Orlov SN, Pchejetski D, Taurin S, Thorin-Trescases N, Maximov GV, Pshezhetsky AV, Rubin AB, Hamet P. Apoptosis in serum-deprived vascular smooth muscle cells: evidence for cell volume-independent mechanism. Apoptosis : An International Journal On Programmed Cell Death. 9: 55-66. PMID 14739599 DOI: 10.1023/B:Appt.0000012122.47197.03  0.702
2004 Taurin S, Pchejetski D, Thorin-Trescase N, Tremblay J, Harriet P, Orlov SN. INTRACELLULAR SODIUM PROTECTS VASCULAR ENDOTHELIAL CELLS FROM APOPTOSIS TRIGGERED BY [3H]-DECAY-INDUCED DNA DAMAGE Journal of Hypertension. 22: S50-S51. DOI: 10.1097/00004872-200406002-00169  0.659
2004 Anfinogenova YJ, Kilin AA, Kovalev IV, Baskakov MB, Dulin NO, Orlov SN. CELL SHRINKAGE-INDUCED VASCULAR SMOOTH MUSCLE CONTRACTION Journal of Hypertension. 22: S44-S45. DOI: 10.1097/00004872-200406002-00147  0.356
2004 Orlov SN, Pchejetski D, Thorin-Trescase N, Taurin S, Tremblay J, Harriet P. ENDOTHELIAL CELL DEATH TRIGGERED BY OUABAIN Journal of Hypertension. 22: S9-S10. DOI: 10.1097/00004872-200406002-00024  0.656
2004 Orlov SN, Pchejetski D, Taurin S, Tremblay J, Harriet P. APOPTOSIS IN VASCULAR SMOOTH MUSCLE CELLS Journal of Hypertension. 22: S7. DOI: 10.1097/00004872-200406002-00014  0.656
2004 Orlov SN, Pchejetski D, Taurin S, Tremblay J, Hamet P. Apoptosis In Serum-Deprived Vascular Smooth Muscle Cells (Vsmc): Evidence For Cell Volume-Independent Mechanism Cardiovascular Pathology. 13: 166. DOI: 10.1016/J.Carpath.2004.03.501  0.669
2004 Taurin S, Pchejetski D, Thorin-Trescases N, Tremblay J, Hamet P, Orlov SN. ELEVATION OF [NA+]I PROTECTS ENDOTHELIAL CELLS FROM APOPTOSIS TRIGGERED BY [3H]-DECAY-INDUCED DNA DAMAGE Cardiovascular Pathology. 13: 92. DOI: 10.1016/J.Carpath.2004.03.271  0.744
2004 Orlov SN, Thorin-Trescases N, Pchejetski D, Taurin S, Tremblay J, Hamet P. ENDOTHELIAL CELL DEATH TRIGGERED BY OUABAIN: EVIDENCE FOR NOVEL FUNCTION OF THE NA+,K+−ATPASE. Cardiovascular Pathology. 13: 54-55. DOI: 10.1016/J.Carpath.2004.03.160  0.719
2004 Hamet P, Orlov SN, deBlois D, Sun Y, Kren V, Tremblay J. Angiotensin as a Cytokine Implicated in Accelerated Cellular Turnover Handbook of Experimental Pharmacology. 163: 71-98. DOI: 10.1007/978-3-642-18495-6_3  0.369
2003 Kovalev IV, Baskakov MB, Anfinogenova YD, Borodin YL, Kilin AA, Minochenko IL, Popov AG, Kapilevich LV, Medvedev MA, Orlov SN. Effect of Na+,K+,2Cl- cotransport inhibitor bumetanide on electrical and contractile activity of smooth muscle cells in guinea pig ureter. Bulletin of Experimental Biology and Medicine. 136: 145-9. PMID 14631495 DOI: 10.1023/A:1026310722105  0.471
2003 Brindikova TA, Bourcier N, Torres B, Pchejetski D, Gekle M, Maximov GV, Montminy V, Insel PA, Orlov SN, Isenring P. Purinergic-induced signaling in C11-MDCK cells inhibits the secretory Na-K-Cl cotransporter. American Journal of Physiology. Cell Physiology. 285: C1445-53. PMID 12917108 DOI: 10.1152/Ajpcell.00386.2002  0.492
2003 Orlov SN. Na+-H+ exchanger as a target for intervention in cardiovascular remodelling. Journal of Hypertension. 21: 1463-5. PMID 12872038 DOI: 10.1097/00004872-200308000-00008  0.307
2003 Taurin S, Hamet P, Orlov SN. [Na/K pump and intracellular monovalent cations: novel mechanism of excitation-transcription coupling involved in inhibition of apoptosis]. Molekuliarnaia Biologiia. 37: 371-81. PMID 12815944 DOI: 10.1023/A:1024266722564  0.741
2003 Orlov SN, Pchejetski DV, Sarkissian SD, Adarichev V, Taurin S, Pshezhetsky AV, Tremblay J, Maximov GV, deBlois D, Bennett MR, Hamet P. [3H]-thymidine labelling of DNA triggers apoptosis potentiated by E1A-adenoviral protein. Apoptosis : An International Journal On Programmed Cell Death. 8: 199-208. PMID 12766480 DOI: 10.1023/A:1022931028235  0.7
2003 Davis A, Hogarth K, Fernandes D, Solway J, Niu J, Kolenko V, Browning D, Miano JM, Orlov SN, Dulin NO. Functional significance of protein kinase A activation by endothelin-1 and ATP: negative regulation of SRF-dependent gene expression by PKA. Cellular Signalling. 15: 597-604. PMID 12681447 DOI: 10.1016/S0898-6568(02)00148-1  0.326
2003 Devlin AM, Solban N, Tremblay S, Gutkowska J, Schürch W, Orlov SN, Lewanczuk R, Hamet P, Tremblay J. HCaRG is a novel regulator of renal epithelial cell growth and differentiation causing G2M arrest American Journal of Physiology - Renal Physiology. 284: F753-F762. PMID 12620924 DOI: 10.1152/Ajprenal.00252.2002  0.357
2003 Pchejetski D, Taurin S, Der Sarkissian S, Lopina OD, Pshezhetsky AV, Tremblay J, deBlois D, Hamet P, Orlov SN. Inhibition of Na+,K+-ATPase by ouabain triggers epithelial cell death independently of inversion of the [Na+]i/[K+]i ratio. Biochemical and Biophysical Research Communications. 301: 735-44. PMID 12565842 DOI: 10.1016/S0006-291X(02)03002-4  0.733
2003 Orlov SN, Pchejetski DV, Sarkissian SD, Adarichev V, Taurin S, Pshezhetsky AV, Tremblay J, Maximov GV, DeBlois D, Bennett MR, Hamet P. [3H]-thymidine labelling of DNA triggers apoptosis potentiated by E1A-adenoviral protein Apoptosis. 8: 199-208. DOI: 10.1023/A:1022931028235  0.676
2002 Taurin S, Seyrantepe V, Orlov SN, Tremblay TL, Thibault P, Bennett MR, Hamet P, Pshezhetsky AV. Proteome analysis and functional expression identify mortalin as an antiapoptotic gene induced by elevation of [Na+]i/[K+]i ratio in cultured vascular smooth muscle cells. Circulation Research. 91: 915-22. PMID 12433836 DOI: 10.1161/01.Res.0000043020.45534.3E  0.73
2002 Taurin S, Dulin NO, Pchejetski D, Grygorczyk R, Tremblay J, Hamet P, Orlov SN. c-Fos expression in ouabain-treated vascular smooth muscle cells from rat aorta: evidence for an intracellular-sodium-mediated, calcium-independent mechanism. The Journal of Physiology. 543: 835-47. PMID 12231642 DOI: 10.1113/Jphysiol.2002.023259  0.706
2002 Bourcier N, Grygorczyk R, Gekle M, Berthiaume Y, Orlov SN. Purinergic-induced ion current in monolayers of C7-MDCK cells: role of basolateral and apical ion transporters. The Journal of Membrane Biology. 186: 131-43. PMID 12148840 DOI: 10.1007/S00232-001-0141-Y  0.463
2002 Taurin S, Ryazhsky GG, Maximova NV, Chuchalin AG, Hamet P, Pshezhetsky AV, Orlov SN. Suppression of programmed cell death by intracellular cAMP is not mediated by expression of genes encoding an inhibitor of apoptosis. Biochemistry. Biokhimii︠a︡. 67: 254-9. PMID 11952423 DOI: 10.1023/A:1014478417580  0.682
2002 Orlov SN, Taurin S, Hamet P. The alpha1-Na/K pump does not mediate the involvement of ouabain in the development of hypertension in rats. Blood Pressure. 11: 56-62. PMID 11926353 DOI: 10.1080/080370502753543972  0.722
2002 deBlois D, Orlov SN, Hamet P. Apoptosis in cardiovascular remodeling--effect of medication. Cardiovascular Drugs and Therapy. 15: 539-45. PMID 11916363 DOI: 10.1023/A:1013723922582  0.349
2002 Orlov SN, Tremblay J, Deblois D, Hamet P. Genetics of programmed cell death and proliferation. Seminars in Nephrology. 22: 161-71. PMID 11891510 DOI: 10.1053/Snep.2002.2002.30434  0.324
2001 Anfinogenova YJ, Rodriguez X, Grygorczyk R, Adragna NC, Lauf PK, Hamet P, Orlov SN. Swelling-induced K(+) fluxes in vascular smooth muscle cells are mediated by charybdotoxin-sensitive K(+) channels. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 11: 295-310. PMID 11832655 DOI: 10.1159/000047816  0.455
2001 Orlov SN, Dutil J, Hamet P, Deng AY. Replacement of (alpha)1-Na-K-ATPase of Dahl rats by Milan rats lowers blood pressure but does not affect its activity. Physiological Genomics. 7: 171-7. PMID 11773603 DOI: 10.1152/Physiolgenomics.00059.2001  0.367
2001 Mongin AA, Orlov SN. Mechanisms of cell volume regulation and possible nature of the cell volume sensor. Pathophysiology : the Official Journal of the International Society For Pathophysiology / Isp. 8: 77-88. PMID 11720802 DOI: 10.1016/S0928-4680(01)00074-8  0.346
2001 Orlov SN, Taurin S, Tremblay J, Hamet P. Inhibition of Na+,K+ pump affects nucleic acid synthesis and smooth muscle cell proliferation via elevation of the [Na+]i/[K+]i ratio: possible implication in vascular remodelling. Journal of Hypertension. 19: 1559-65. PMID 11564975 DOI: 10.1097/00004872-200109000-00007  0.735
2001 Dulin NO, Orlov SN, Kitchen CM, Voyno-Yasenetskaya TA, Miano JM. G-protein-coupled-receptor activation of the smooth muscle calponin gene. The Biochemical Journal. 357: 587-92. PMID 11439113 DOI: 10.1042/Bj3570587  0.339
2001 Thorin-Trescases N, Orlov SN, Taurin S, Dulin NO, Allen BG, deBlois D, Tremblay J, Pshezhetsky AV, Hamet P. Antiproliferative effect of brief exposure to cholera toxin in vascular smooth muscle cells: role of cAMP and protein kinase A. Canadian Journal of Physiology and Pharmacology. 79: 471-80. PMID 11430584 DOI: 10.1139/Y01-017  0.66
2001 Maksimov GV, Maksimova NV, Churin AA, Orlov SN, Rubin AB. Study on conformational changes in hemoglobin protoporphyrin in essential hypertension. Biochemistry. Biokhimiia. 66: 295-9. PMID 11333153 DOI: 10.1023/A:1010251813632  0.331
2001 Thorin-Trescases N, Ono Y, Tremblay J, Hamet P, Orlov SN. Dual effect of adenosine on vascular smooth muscle [(3)H]-thymidine DNA labeling: receptor-mediated modulation of DNA synthesis and inhibition of thymidine uptake. Journal of Vascular Research. 37: 477-84. PMID 11146401 DOI: 10.1159/000054080  0.342
2000 Skriabin G, Orlov S, Masse C, Berthiaume Y. Phloretin inhibits Na+ and K+ uptake in cultured alveolar type II cells by reduction of cellular ATP content. Experimental Lung Research. 26: 319-333. PMID 10914331 DOI: 10.1080/019021400408281  0.491
2000 Orlov SN, Taurin S, Thorin-Trescases N, Dulin NO, Tremblay J, Hamet P. Inversion of the intracellular Na(+)/K(+) ratio blocks apoptosis in vascular smooth muscle cells by induction of RNA synthesis. Hypertension. 35: 1062-8. PMID 10818065 DOI: 10.1161/01.Hyp.35.5.1062  0.679
2000 Adragna NC, White RE, Orlov SN, Lauf PK. K-Cl cotransport in vascular smooth muscle and erythrocytes: possible implication in vasodilation. American Journal of Physiology. Cell Physiology. 278: C381-90. PMID 10666034 DOI: 10.1152/Ajpcell.2000.278.2.C381  0.476
2000 Orlov SN, Adarichev VA, Devlin AM, Maximova NV, Sun YL, Tremblay J, Dominiczak AF, Postnov YV, Hamet P. Increased Na(+)/H(+) exchanger isoform 1 activity in spontaneously hypertensive rats: lack of mutations within the coding region of NHE1. Biochimica Et Biophysica Acta. 1500: 169-80. PMID 10657586 DOI: 10.1016/S0925-4439(99)00101-5  0.446
2000 Rodriguez PX, Ono Y, Sun Y, Hamet P, Orlov SN, Tremblay J. THERMOPROTECTION OF VASCULAR SMOOTH MUSCLE ION TRANSPORTERS Journal of Hypertension. 18: S183. DOI: 10.1097/00004872-200006001-00634  0.308
2000 Wang TT, Orlov S, Tremblay J, Hamet P. ANTISENSE OLIGODEOXYNUCLEOTIDE FOR TRANSFORMING GROWTH FACTOR β1 MODULATES CELL PROLIFERATION AND APOPTOSIS IN VASCULAR SMOOTH MUSCLE CELLS Journal of Hypertension. 18: S148. DOI: 10.1097/00004872-200006001-00506  0.352
2000 Orlov SN, Dulin NO, Gagnon F, Gekle M, Douglas JG, Schwartz JH, Hamet P. PURINERGIC INHIBITION OF RENAL Na,K,CI COTRANSPORT Journal of Hypertension. 18: S104-S105. DOI: 10.1097/00004872-200006001-00352  0.399
2000 Orlov SN, Taurin S, Tremblay J, Hamet P. INTRACELLULAR Na+/K+ RATIO AND cAMP SIGNALLING Journal of Hypertension. 18: S76. DOI: 10.1097/00004872-200006001-00260  0.693
1999 Orlov SN, Adragna NC, Adarichev VA, Hamet P. Genetic and biochemical determinants of abnormal monovalent ion transport in primary hypertension. American Journal of Physiology. Cell Physiology. 276: C511-C536. PMID 29591009 DOI: 10.1152/Ajpcell.1999.276.3.C511  0.399
1999 Orlov SN, Pausova Z, Gossard F, Gaudet D, Tremblay J, Kotchen T, Cowley A, Larochelle P, Hamet P. Sibling resemblance of erythrocyte ion transporters in French-Canadian sibling-pairs affected with essential hypertension. Journal of Hypertension. 17: 1859-65. PMID 10703881 DOI: 10.1097/00004872-199917121-00013  0.379
1999 Orlov SN, Dulin NO, Gagnon F, Gekle M, Douglas JG, Schwartz JH, Hamet P. Purinergic modulation of Na(+),K(+),Cl(-) cotransport and MAP kinases is limited to C11-MDCK cells resembling intercalated cells from collecting ducts. The Journal of Membrane Biology. 172: 225-34. PMID 10568792 DOI: 10.1007/S002329900599  0.488
1999 Gagnon F, Orlov SN, Champagne MJ, Tremblay J, Hamet P. Heat stress preconditioning does not protect renal epithelial Na(+),K(+),Cl(-) and Na(+),P(i) cotransporters from their modulation by severe heat stress. Biochimica Et Biophysica Acta. 1421: 163-74. PMID 10561481 DOI: 10.1016/S0005-2736(99)00127-3  0.348
1999 Orlov SN, Thorin-Trescases N, Dulin NO, Dam TV, Fortuno MA, Tremblay J, Hamet P. Activation of cAMP signaling transiently inhibits apoptosis in vascular smooth muscle cells in a site upstream of caspase-3. Cell Death and Differentiation. 6: 661-72. PMID 10453077 DOI: 10.1038/Sj.Cdd.4400539  0.403
1999 Orlov SN, Thorin-Trescases N, Kotelevtsev SV, Tremblay J, Hamet P. Inversion of the intracellular Na+/K+ ratio blocks apoptosis in vascular smooth muscle at a site upstream of caspase-3. The Journal of Biological Chemistry. 274: 16545-52. PMID 10347219 DOI: 10.1074/Jbc.274.23.16545  0.531
1999 Champagne MJ, Dumas P, Orlov SN, Bennett MR, Hamet P, Tremblay J. Protection against necrosis but not apoptosis by heat-stress proteins in vascular smooth muscle cells: evidence for distinct modes of cell death. Hypertension. 33: 906-13. PMID 10082507 DOI: 10.1161/01.Hyp.33.3.906  0.38
1999 Gagnon F, Dulin NO, Tremblay J, Hamet P, Orlov SN. ATP-induced inhibition of Na+, K+, Cl- cotransport in Madin-Darby canine kidney cells: lack of involvement of known purinoceptor-coupled signaling pathways. The Journal of Membrane Biology. 167: 193-204. PMID 9916150 DOI: 10.1007/S002329900483  0.498
1999 Gagnon F, Hamet P, Orlov SN. Na+,K+ pump and Na+-coupled ion carriers in isolated mammalian kidney epithelial cells: regulation by protein kinase C Canadian Journal of Physiology and Pharmacology. 77: 305-319. DOI: 10.1139/Y99-041  0.508
1998 Orlov SN, Kuznetsov SR, Pokudin NI, Tremblay J, Hamet P. Can we use erythrocytes for the study of the activity of the ubiquitous Na+/H+ exchanger (NHE-1) in essential hypertension? American Journal of Hypertension. 11: 774-83. PMID 9683037 DOI: 10.1016/S0895-7061(98)00039-9  0.439
1998 Gagnon F, Orlov SN, Tremblay J, Hamet P. Complete inhibition of Na+, K+, Cl- cotransport in Madin-Darby canine kidney cells by PMA-sensitive protein kinase. Biochimica Et Biophysica Acta. 1369: 233-9. PMID 9518630 DOI: 10.1016/S0005-2736(97)00225-3  0.509
1998 Orlov SN, Aksentsev SL, Pokudin NI, Tremblay J, Hamet P. Na+/H+ exchange in vascular smooth muscle cells is controlled by GTP-binding proteins. Hypertension (Dallas, Tex. : 1979). 31: 259-65. PMID 9453313 DOI: 10.1161/01.Hyp.31.1.259  0.423
1998 Orlov S, Adarichev V, Sun Y, Tremblay J, Hamet P. An activation of NHE1 isoform of Na+/H+ exchanger in primary hypertension: Role of GTP-binding proteins Pathophysiology. 5: 36. DOI: 10.1016/S0928-4680(98)80414-8  0.365
1997 Mongin AA, Aksentsev SL, Orlov SN, Konev SV. Hypoosmotic shock activates Ca2+ channels in isolated nerve terminals Neurochemistry International. 31: 835-843. PMID 9413845 DOI: 10.1016/S0197-0186(97)00033-8  0.316
1997 Orlov SN, Tremblay J, Hamet P. Bumetanide-sensitive ion fluxes in vascular smooth muscle cells: lack of functional Na+, K+, 2 Cl- cotransport. The Journal of Membrane Biology. 153: 125-35. PMID 8703202 DOI: 10.1007/S002329900116  0.513
1997 ORLOV S. D3 Can we use red blood cells (RBC) for the study of the ubiquitous and renal specific forms of Na+/H+ exchanger in essential hypertension? American Journal of Hypertension. 10: 39A. DOI: 10.1016/S0895-7061(97)88777-8  0.352
1996 Mongin AA, Aksentsev SL, Orlov SN, Kvacheva ZB, Mezen NI, Fedulov AS, Konev SV. Swelling-induced activation of Na+,K+,2Cl- cotransport in C6 glioma cells: Kinetic properties and intracellular signalling mechanisms Biochimica Et Biophysica Acta - Biomembranes. 1285: 229-236. PMID 8972707 DOI: 10.1016/S0005-2736(96)00165-4  0.49
1996 Orlov SN, Tremblay J, Hamet P. Cell volume in vascular smooth muscle is regulated by bumetanide-sensitive ion transport. The American Journal of Physiology. 270: C1388-97. PMID 8967439 DOI: 10.1152/Ajpcell.1996.270.5.C1388  0.472
1996 Orlov SN, Dam TV, Tremblay J, Hamet P. Apoptosis in vascular smooth muscle cells: role of cell shrinkage. Biochemical and Biophysical Research Communications. 221: 708-15. PMID 8630026 DOI: 10.1006/Bbrc.1996.0661  0.403
1996 Orlov SN, Tremblay J, Hamet P. cAMP signaling inhibits dihydropyridine-sensitive Ca2+ influx in vascular smooth muscle cells. Hypertension (Dallas, Tex. : 1979). 27: 774-80. PMID 8613239 DOI: 10.1161/01.Hyp.27.3.774  0.419
1996 Hamet P, deBlois D, Dam T-, Richard L, Teiger E, Tea B-, Orlov SN, Tremblay J. Apoptosis and vascular wall remodeling in hypertension Canadian Journal of Physiology and Pharmacology. 74: 850-861. DOI: 10.1139/Y96-076  0.399
1995 Sen CK, Kolosova I, Hänninen O, Orlov SN. Inward potassium transport systems in skeletal muscle derived cells are highly sensitive to oxidant exposure. Free Radical Biology & Medicine. 18: 795-800. PMID 7750802 DOI: 10.1016/0891-5849(94)00174-I  0.458
1995 Sen CK, Hänninen O, Orlov SN. Unidirectional sodium and potassium flux in myogenic L6 cells: mechanisms and volume-dependent regulation. Journal of Applied Physiology (Bethesda, Md. : 1985). 78: 272-81. PMID 7713823 DOI: 10.1152/Jappl.1995.78.1.272  0.502
1995 Hamet P, Richard L, Dam TV, Teiger E, Orlov SN, Gaboury L, Gossard F, Tremblay J. Apoptosis in target organs of hypertension. Hypertension (Dallas, Tex. : 1979). 26: 642-8. PMID 7558225 DOI: 10.1161/01.Hyp.26.4.642  0.369
1995 Orlov SN, Tremblay J, Hamet P. Altered beta-adrenergic regulation of Na-K-Cl cotransport in cultured smooth muscle cells from the aorta of spontaneously hypertensive rats. Role of the cytoskeleton network. American Journal of Hypertension. 8: 739-47. PMID 7546501 DOI: 10.1016/0895-7061(95)00074-Y  0.487
1995 Nagdaliev FF, Kotelevtsev SV, Kozlovskaya VI, German AV, Orlov SN. Ion transport and its adrenergic regulation in erythrocyte membranes of the bream abramis brama injected with a mixture of polychlorinated biphenyls Bulletin of Experimental Biology and Medicine. 120: 1013-1015. DOI: 10.1007/Bf02444970  0.382
1994 Kuchkina NV, Orlov SN, Pokudin NI, Chuchalin AG. Volume-dependent regulation of the respiratory burst of activated human neutrophils. Experientia. 49: 995-7. PMID 8253173 DOI: 10.1007/Bf02125647  0.336
1994 Aksentsev SL, Mongin AA, Orlov SN, Rakovich AA, Kaler GV, Konev SV. Osmotic regulation of sodium pump in rat brain synaptosomes: the role of cytoplasmic sodium Brain Research. 644: 1-6. PMID 8032937 DOI: 10.1016/0006-8993(94)90338-7  0.418
1994 Mongin AA, Aksentsev SL, Orlov SN, Slepko NG, Kozlova MV, Maximov GV, Konev SV. Swelling-induced K+ influx in cultured primary astrocytes Brain Research. 655: 110-114. PMID 7812761 DOI: 10.1016/0006-8993(94)91603-9  0.466
1994 Pokuden NI, Menshikov MY, Robertson D, Robertson RM, Orlov SN, Tkachuk VA, Postnov YV. Raised free calcium in the platelet of the spontaneously hypertensive rat: Regulation by adenosine diphosphate and epinephrine Current Therapeutic Research. 55: 290-302. DOI: 10.1016/S0011-393X(05)80172-9  0.309
1994 Orlov SN, Cragoe EJ, Hänninen O. Volume- and catecholamine-dependent regulation of Na/H antiporter and unidirectional potassium fluxes in Salmo trutta red blood cells Journal of Comparative Physiology B. 164: 135-140. DOI: 10.1007/Bf00301655  0.506
1993 Orlov SN, Sen CK, Kolosova IA, Bernhardt J, Hänninen O, Bühler FR. Evidence for the involvement of G proteins in the modulation of 22Na and 45Ca fluxes in myogenic L6 and aortic smooth muscle cells. Biochemical and Biophysical Research Communications. 191: 802-10. PMID 8466517 DOI: 10.1006/Bbrc.1993.1288  0.466
1993 Orlov SN, Kolosova IA, Cragoe EJ, Gurlo TG, Mongin AA, Aksentsev SL, Konev SV. Kinetics and peculiarities of thermal inactivation of volume-induced Na+/H+ exchange, Na+, K+, 2Cl- cotransport and K+, Cl- cotransport in rat erythrocytes Bba - Biomembranes. 1151: 186-192. PMID 8396975 DOI: 10.1016/0005-2736(93)90103-7  0.471
1993 Resink TJ, Rybin V, Bernhardt J, Orlov S, Bühler FR, Tkachuk VA. Cellular Signalling by Lipoproteins in Cultured Smooth Muscle Cells from Spontaneously Hypertensive Rats Journal of Vascular Research. 30: 169-180. PMID 8390863 DOI: 10.1159/000158992  0.332
1993 Orlov S, Skryabin G. Catecholamine- and volume-dependent ion fluxes in carp (Cyprinus carpio) red blood cells Journal of Comparative Physiology B. 163. DOI: 10.1007/Bf00265647  0.51
1992 Orlov SN, Resink TJ, Bernhardt J, Buhler FR. Volume-dependent regulation of sodium and potassium fluxes in cultured vascular smooth muscle cells: dependence on medium osmolality and regulation by signalling systems. The Journal of Membrane Biology. 129: 199-210. PMID 1331467 DOI: 10.1007/Bf00219515  0.529
1992 Orlov SN, Resink TJ, Bernhardt J, B??hler FR. Na+-K+ pump and Na+-K+ co-transport in cultured vascular smooth muscle cells from spontaneously hypertensive and normotensive rats Journal of Hypertension. 10: 6. DOI: 10.1097/00004872-199208000-00006  0.395
1992 Adamchik AS, Sushkevich GN, Orlov SN, Pokudin NI, Kubatiev AA. Effect of ultraviolet irradiation on rate of Na+/H+ exchange in erythrocytes of normal individuals and patients with atherosclerosis of lower limb arteries Bulletin of Experimental Biology and Medicine. 114: 1233-1235. DOI: 10.1007/Bf00809543  0.315
1991 Petrunyaka VV, Panyushkina EA, Severina EP, Orlov SN. The ATPase activity of saponin-treated rat erythrocytes: regulation by monovalent cations, calcium, ouabain, and furosemide. Biochimica Et Biophysica Acta. 1030: 279-88. PMID 2175654 DOI: 10.1016/0005-2736(90)90304-7  0.432
1991 Orlov SN, Pokudin NI, Postnov YV. 86Rb and 22Na transport in primary cultured renal cells from spontaneously hypertensive rats Journal of Hypertension. 9: S292. DOI: 10.1097/00004872-199112000-00129  0.362
1991 Khomichuk AY, Timoshin SS, Orlov SN, Pokudin NI, Kubatiev AA. Hydra peptide morphogen activates Na/H exchange in human erythrocytes Bulletin of Experimental Biology and Medicine. 111: 763-764. DOI: 10.1007/Bf00840174  0.311
1990 Kotelevtsev YV, Spitkovski DD, Orlov SN, Postnov YV. Interstrain restriction fragment length polymorphism in the c-src correlates with Na,K cotransport and calcium content in hybrid rat erythrocytes. Journal of Hypertension. Supplement : Official Journal of the International Society of Hypertension. 7: S112-3. PMID 2576661 DOI: 10.1097/00004872-198900076-00052  0.386
1989 Orlov SN, Pokudin NI, Kotelevtsev YV, Gulak PV. Volume-dependent regulation of ion transport and membrane phosphorylation in human and rat erythrocytes. The Journal of Membrane Biology. 107: 105-17. PMID 2541247 DOI: 10.1007/Bf01871716  0.419
1989 Kotelevtsev YV, Spitkovskii DD, Orlov SN, Postnov YV. c-src Locus determines increased rate of Na+, K+-cotransport and increased calcium content in (SHR�WKY)F2 hybrid erythrocytes Bulletin of Experimental Biology and Medicine. 108: 1634-1636. DOI: 10.1007/Bf00839709  0.371
1988 Postnov YV, Kravtsov GM, Orlov SN, Pokudin NI, Postnov IY, Kotelevtsev YV. Effect of protein kinase C activation on cytoskeleton and cation transport in human erythrocytes. Reproduction of some membrane abnormalities revealed in essential hypertension. Hypertension (Dallas, Tex. : 1979). 12: 267-73. PMID 3169942 DOI: 10.1161/01.Hyp.12.3.267  0.423
1988 Orlov SN, Pokudin NI, Postnov YV. Calcium transport in erythrocytes of rats with spontaneous hypertension Journal of Hypertension. 6: 829???838. DOI: 10.1097/00004872-198810000-00010  0.334
1988 Orlov SN, Pokudin NI, Postnov YV. Transport of sodium and protons and hypotonic haemolysis in the valinomycin-treated erythrocytes of rats with spontaneous hypertension Journal of Hypertension. 6: 351???360. DOI: 10.1097/00004872-198805000-00003  0.421
1988 Orlov SN, Postnov IY, Pokudin NI, Kukharenko VY, Postnov YV. Increased Na+/H+ exchange in erythrocytes of hypertensive patients Bulletin of Experimental Biology and Medicine. 106: 1246-1249. DOI: 10.1007/Bf00834485  0.357
1987 Kotelevtsev YV, Orlov SN, Pokudin NI, Agnaev VM, Postnov YV. Genetic analysis of inheritance of rates of Na+, K+-cotransport, calcium concentration in erythrocytes, and blood pressure of F2 hybrids of spontaneously hypertensive and normotensive rats Bulletin of Experimental Biology and Medicine. 103: 518-520. DOI: 10.1007/Bf00842486  0.336
1987 Pokudin NI, Orlov SN, Postnov YV. Na+/H+ exchange in erythrocytes of spontaneously hypertensive rats Bulletin of Experimental Biology and Medicine. 104: 1364-1367. DOI: 10.1007/Bf00834945  0.359
1985 Postnov YV, Orlov SN. Cell membrane alteration as a source of primary hypertension. Journal of Hypertension. 2: 1-6. PMID 6397521 DOI: 10.1097/00004872-198402000-00001  0.304
1985 Kravtsov GM, Orlov SN, Postnov YV. Aggregation, membrane potential, and transport in platelets of spontaneously hypertensive rats. Pflugers Archiv : European Journal of Physiology. 402: 330-6. PMID 6097870 DOI: 10.1007/Bf00585519  0.311
1983 Aksentsev SL, Rakovich AA, Okoon IM, Konev SV, Orlov SN, Kravtsov GM. Effect of tetracaine on veratrine-mediated influx of sodium into rat brain synaptosomes. PflüGers Archiv: European Journal of Physiology. 397: 135-140. PMID 6866729 DOI: 10.1007/Bf00582051  0.306
1983 Orlov SN, Pokudin NI. Calmodulin-dependent Ca2+ transport in erythrocytes of spontaneously hypertensive rats. Pflugers Archiv : European Journal of Physiology. 397: 54-6. PMID 6866721 DOI: 10.1007/Bf00585168  0.331
1983 Kravtsov GM, Orlov SN, Pokudin NI. Calcium transport in synaptosomes and subcellular membrane fractions of brain tissue in spontaneously hypertensive rats. Clinical Science (London, England : 1979). 65: 127-35. PMID 6861445 DOI: 10.1042/Cs0650127  0.356
1983 Orlov SN, Pokudin NI, Reznikova MB, Rjazhsky GG, Postnov YV. On the interrelation between calmodulin and EGTA in the regulation of the affinity to Ca2+ and the maximal activity of the erythrocyte-membrane calcium pump. European Journal of Biochemistry. 132: 315-9. PMID 6404633 DOI: 10.1111/J.1432-1033.1983.Tb07364.X  0.328
1982 Orlov SN, Pokudin NI, Kravtsov GM. Effect of monovalent cations on calcium transport in mitochondria Bulletin of Experimental Biology and Medicine. 93: 601-604. DOI: 10.1007/Bf00830770  0.432
1981 Orlov SN, Postnov YV. Calcium accumulation and calcium binding by the cell membranes of cardiomyocytes and smooth muscle of aorta in spontaneously hypertensive rats. Clinical Science (London, England : 1979). 207s-209s. PMID 7449260 DOI: 10.1042/Cs059207S  0.309
1980 Postnov YV, Orlov SN. Evidence of altered calcium accumulation and calcium binding by the membranes of adipocytes in spontaneously hypertensive rats. Pflugers Archiv : European Journal of Physiology. 385: 85-9. PMID 7191099 DOI: 10.1007/Bf00583919  0.315
1979 Postnov YV, Orlov SN, Pokudin NI. Decrease of calcium binding by the red blood cell membrane in spontaneously hypertensive rats and in essential hypertension. Pflugers Archiv : European Journal of Physiology. 379: 191-5. PMID 571115 DOI: 10.1007/Bf00586947  0.342
1978 Orlov SN, Shevchenko AS, Postnov YV. Role of membrane-bound calcium in changes in ATPase activity, permeability, and structural state of the human erythrocyte membrane Bulletin of Experimental Biology and Medicine. 85: 745-748. DOI: 10.1007/Bf00806153  0.348
1977 Postnov YV, Orlov SN, Shevchenko AS. Changes in binding of calcium ions and in function of Na+, K+-ATPase in the erythrocytes in essential hypertension Bulletin of Experimental Biology and Medicine. 84: 967-969. DOI: 10.1007/Bf00798518  0.386
1976 Postnov YV, Orlov SN, Gulak PV, Shevchenko AS. Evidence of altered permeability of the erythrocyte membrane for sodium and potassium ions in spontaneously hypertensive rats. Clinical Science. 3. PMID 1071599 DOI: 10.1042/Cs051169S  0.409
1976 Postnov YU, Orlov S, Gulak P, Shevchenko A. Altered permeability of the erythrocyte membrane for sodium and potassium ions in spontaneously hypertensive rats. Pflugers Archiv : European Journal of Physiology. 365: 257-63. PMID 988566 DOI: 10.1007/Bf01067026  0.413
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