Year |
Citation |
Score |
2023 |
Esquea EM, Young RG, Reginato MJ. Fructose promotes liver cancer via microbial acetate-induced O-GlcNAcylation. Trends in Endocrinology and Metabolism: Tem. PMID 38097465 DOI: 10.1016/j.tem.2023.12.002 |
0.372 |
|
2023 |
Le Minh G, Esquea EM, Young RG, Huang J, Reginato MJ. On a sugar high: Role of O-GlcNAcylation in cancer. The Journal of Biological Chemistry. 299: 105344. PMID 37838167 DOI: 10.1016/j.jbc.2023.105344 |
0.529 |
|
2023 |
Le Minh G, Esquea EM, Dhameliya TT, Merzy J, Lee MH, Ball LE, Reginato MJ. Kruppel-like factor 8 regulates triple negative breast cancer stem cell-like activity. Frontiers in Oncology. 13: 1141834. PMID 37152043 DOI: 10.3389/fonc.2023.1141834 |
0.516 |
|
2022 |
Le Minh G, Reginato MJ. Role of O-GlcNAcylation on cancer stem cells: Connecting nutrient sensing to cell plasticity. Advances in Cancer Research. 157: 195-228. PMID 36725109 DOI: 10.1016/bs.acr.2022.06.002 |
0.539 |
|
2022 |
Ciraku L, Bacigalupa ZA, Ju J, Moeller RA, Le Minh G, Lee RH, Smith MD, Ferrer CM, Trefely S, Izzo LT, Doan MT, Gocal WA, D'Agostino L, Shi W, Jackson JG, ... ... Reginato MJ, et al. O-GlcNAc transferase regulates glioblastoma acetate metabolism via regulation of CDK5-dependent ACSS2 phosphorylation. Oncogene. PMID 35190642 DOI: 10.1038/s41388-022-02237-6 |
0.828 |
|
2021 |
Ciraku L, Esquea EM, Reginato MJ. O-GlcNAcylation regulation of cellular signaling in cancer. Cellular Signalling. 110201. PMID 34800629 DOI: 10.1016/j.cellsig.2021.110201 |
0.463 |
|
2020 |
Akella NM, Le Minh G, Ciraku L, Mukherjee A, Bacigalupa ZA, Mukhopadhyay D, Sodi VL, Reginato MJ. O-GlcNAc Transferase Regulates Cancer Stem-like Potential of Breast Cancer Cells. Molecular Cancer Research : McR. PMID 31974291 DOI: 10.1158/1541-7786.Mcr-19-0732 |
0.822 |
|
2019 |
Akella NM, Ciraku L, Reginato MJ. Fueling the fire: emerging role of the hexosamine biosynthetic pathway in cancer. Bmc Biology. 17: 52. PMID 31272438 DOI: 10.1186/S12915-019-0671-3 |
0.827 |
|
2019 |
Delaney LJ, Ciraku L, Oeffinger BE, Wessner CE, Liu JB, Li J, Nam K, Forsberg F, Leeper DB, O'Kane P, Wheatley MA, Reginato MJ, Eisenbrey JR. Breast Cancer Brain Metastasis Response to Radiation After Microbubble Oxygen Delivery in a Murine Model. Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine. PMID 31124171 DOI: 10.1002/Jum.15031 |
0.467 |
|
2018 |
Bacigalupa ZA, Bhadiadra CH, Reginato MJ. O-GlcNAcylation: key regulator of glycolytic pathways. Journal of Bioenergetics and Biomembranes. PMID 29344764 DOI: 10.1007/S10863-018-9742-3 |
0.858 |
|
2017 |
Sodi VL, Bacigalupa ZA, Ferrer CM, Lee JV, Gocal WA, Mukhopadhyay D, Wellen KE, Ivan M, Reginato MJ. Nutrient sensor O-GlcNAc transferase controls cancer lipid metabolism via SREBP-1 regulation. Oncogene. PMID 29059153 DOI: 10.1038/Onc.2017.395 |
0.824 |
|
2017 |
Beatty A, Fink LS, Singh T, Strigun A, Peter E, Ferrer CM, Nicolas E, Cai KQ, Moran TP, Reginato MJ, Rennefahrt U, Peterson JR. Metabolite profiling reveals the glutathione biosynthetic pathway as a therapeutic target in triple negative breast cancer. Molecular Cancer Therapeutics. PMID 29021292 DOI: 10.1158/1535-7163.Mct-17-0407 |
0.829 |
|
2017 |
Segovia-Mendoza M, Díaz L, Prado-Garcia H, Reginato MJ, Larrea F, García-Becerra R. The addition of calcitriol or its synthetic analog EB1089 to lapatinib and neratinib treatment inhibits cell growth and promotes apoptosis in breast cancer cells. American Journal of Cancer Research. 7: 1486-1500. PMID 28744399 |
0.46 |
|
2016 |
Li C, Li N, Liu X, Zhang EY, Sun Y, Masuda K, Li J, Sun J, Morrison T, Li X, Chen Y, Wang J, Karim NA, Zhang Y, Blenis J, ... Reginato MJ, et al. Proapoptotic protein Bim attenuates estrogen-enhanced survival in lymphangioleiomyomatosis. Jci Insight. 1: e86629. PMID 27882343 DOI: 10.1172/Jci.Insight.86629 |
0.385 |
|
2016 |
Ferrer CM, Lu TY, Bacigalupa ZA, Katsetos CD, Sinclair DA, Reginato MJ. O-GlcNAcylation regulates breast cancer metastasis via SIRT1 modulation of FOXM1 pathway. Oncogene. PMID 27345396 DOI: 10.1038/Onc.2016.228 |
0.857 |
|
2016 |
Ferrer CM, Sodi VL, Reginato MJ. O-GlcNAcylation in Cancer Biology: Linking Metabolism and Signaling. Journal of Molecular Biology. PMID 27343361 DOI: 10.1016/J.Jmb.2016.05.028 |
0.842 |
|
2015 |
Ferrer CM, Reginato MJ. Sweet connections: O-GlcNAcylation links cancer cell metabolism and survival. Molecular & Cellular Oncology. 2: e961809. PMID 27308381 DOI: 10.4161/23723548.2014.961809 |
0.841 |
|
2015 |
Karakashev SV, Reginato MJ. Progress toward overcoming hypoxia-induced resistance to solid tumor therapy. Cancer Management and Research. 7: 253-64. PMID 26316817 DOI: 10.2147/Cmar.S58285 |
0.821 |
|
2015 |
Katsetos CD, Reginato MJ, Baas PW, D'Agostino L, Legido A, Tuszyn Ski JA, Dráberová E, Dráber P. Emerging microtubule targets in glioma therapy. Seminars in Pediatric Neurology. 22: 49-72. PMID 25976261 DOI: 10.1016/J.Spen.2015.03.009 |
0.383 |
|
2015 |
Sodi VL, Khaku S, Krutilina R, Schwab LP, Vocadlo DJ, Seagroves TN, Reginato MJ. mTOR/MYC Axis Regulates O-GlcNAc Transferase Expression and O-GlcNAcylation in Breast Cancer. Molecular Cancer Research : McR. 13: 923-33. PMID 25636967 DOI: 10.1158/1541-7786.Mcr-14-0536 |
0.859 |
|
2015 |
Karakashev SV, Reginato MJ. Hypoxia/HIF1α induces lapatinib resistance in ERBB2-positive breast cancer cells via regulation of DUSP2. Oncotarget. 6: 1967-80. PMID 25596742 DOI: 10.18632/Oncotarget.2806 |
0.835 |
|
2015 |
Tchafa AM, Ta M, Reginato MJ, Shieh AC. EMT Transition Alters Interstitial Fluid Flow-Induced Signaling in ERBB2-Positive Breast Cancer Cells. Molecular Cancer Research : McR. 13: 755-64. PMID 25566992 DOI: 10.1158/1541-7786.Mcr-14-0471 |
0.532 |
|
2015 |
Karakashev S, Reginato M. Abstract 716: Targeting Mek-Erk pathway abrogates hypoxia-mediated lapatinib resistance in ErbB2-positive breast cancer cells Cancer Research. 75: 716-716. DOI: 10.1158/1538-7445.Am2015-716 |
0.832 |
|
2015 |
Sodi VL, Bacigalupa Z, Ferrer C, Reginato M. Abstract 1194: O-GlcNAcylation regulates breast cancer lipid metabolism via sterol regulatory element binding protein 1 Cancer Research. 75: 1194-1194. DOI: 10.1158/1538-7445.Am2015-1194 |
0.835 |
|
2014 |
Ferrer CM, Reginato MJ. Cancer metabolism: cross talk between signaling and O-GlcNAcylation. Methods in Molecular Biology (Clifton, N.J.). 1176: 73-88. PMID 25030920 DOI: 10.1007/978-1-4939-0992-6_7 |
0.835 |
|
2014 |
Ferrer CM, Lynch TP, Sodi VL, Falcone JN, Schwab LP, Peacock DL, Vocadlo DJ, Seagroves TN, Reginato MJ. O-GlcNAcylation regulates cancer metabolism and survival stress signaling via regulation of the HIF-1 pathway. Molecular Cell. 54: 820-31. PMID 24857547 DOI: 10.1016/J.Molcel.2014.04.026 |
0.836 |
|
2014 |
Ferrer CM, Reginato MJ. Sticking to sugars at the metastatic site: sialyltransferase ST6GalNAc2 acts as a breast cancer metastasis suppressor. Cancer Discovery. 4: 275-7. PMID 24596201 DOI: 10.1158/2159-8290.Cd-14-0075 |
0.834 |
|
2014 |
Martín-Pérez R, Palacios C, Yerbes R, Cano-González A, Iglesias-Serret D, Gil J, Reginato MJ, López-Rivas A. Activated ERBB2/HER2 licenses sensitivity to apoptosis upon endoplasmic reticulum stress through a PERK-dependent pathway. Cancer Research. 74: 1766-77. PMID 24453000 DOI: 10.1158/0008-5472.Can-13-1747 |
0.462 |
|
2014 |
Kambach DM, Sodi VL, Lelkes PI, Azizkhan-Clifford J, Reginato MJ. ErbB2, FoxM1 and 14-3-3ζ prime breast cancer cells for invasion in response to ionizing radiation. Oncogene. 33: 589-98. PMID 23318431 DOI: 10.1038/Onc.2012.629 |
0.818 |
|
2013 |
Ferdin J, Nishida N, Wu X, Nicoloso MS, Shah MY, Devlin C, Ling H, Shimizu M, Kumar K, Cortez MA, Ferracin M, Bi Y, Yang D, Czerniak B, Zhang W, ... ... Reginato MJ, et al. HINCUTs in cancer: hypoxia-induced noncoding ultraconserved transcripts. Cell Death and Differentiation. 20: 1675-87. PMID 24037088 DOI: 10.1038/Cdd.2013.119 |
0.445 |
|
2013 |
Whelan KA, Schwab LP, Karakashev SV, Franchetti L, Johannes GJ, Seagroves TN, Reginato MJ. The oncogene HER2/neu (ERBB2) requires the hypoxia-inducible factor HIF-1 for mammary tumor growth and anoikis resistance. The Journal of Biological Chemistry. 288: 15865-77. PMID 23585570 DOI: 10.1074/Jbc.M112.426999 |
0.833 |
|
2013 |
Botta GP, Reichert M, Reginato MJ, Heeg S, Rustgi AK, Lelkes PI. ERK2-regulated TIMP1 induces hyperproliferation of K-Ras(G12D)-transformed pancreatic ductal cells. Neoplasia (New York, N.Y.). 15: 359-72. PMID 23555182 DOI: 10.1593/Neo.121708 |
0.331 |
|
2012 |
Yerbes R, López-Rivas A, Reginato MJ, Palacios C. Control of FLIP L expression and TRAIL resistance by the extracellular signal-regulated kinase1/2 pathway in breast epithelial cells Cell Death & Differentiation. 19: 1908-1916. PMID 22722337 DOI: 10.1038/Cdd.2012.78 |
0.489 |
|
2012 |
Lynch TP, Ferrer CM, Jackson SR, Shahriari KS, Vosseller K, Reginato MJ. Critical role of O-Linked β-N-acetylglucosamine transferase in prostate cancer invasion, angiogenesis, and metastasis. The Journal of Biological Chemistry. 287: 11070-81. PMID 22275356 DOI: 10.1074/Jbc.M111.302547 |
0.857 |
|
2012 |
Botta GP, Reginato MJ, Reichert M, Rustgi AK, Lelkes PI. Constitutive K-RasG12D activation of ERK2 specifically regulates 3D invasion of human pancreatic cancer cells via MMP-1. Molecular Cancer Research : McR. 10: 183-96. PMID 22160930 DOI: 10.1158/1541-7786.Mcr-11-0399 |
0.355 |
|
2012 |
Kambach DM, Sodi V, Lelkes PI, Reginato M, Azizkhan-Clifford J. Abstract LB-212: Ionizing radiation selectively promotes invasion of ErbB2-expressing breast cancer cells via regulation of FoxM1 Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-212 |
0.817 |
|
2012 |
Qie S, Chu C, Li W, Wang C, Reginato M, Sang N. Abstract 5143: ErbB2 activation up-regulates glutaminase 1 expression via NF-κB pathway Cancer Research. 72: 5143-5143. DOI: 10.1158/1538-7445.Am2012-5143 |
0.583 |
|
2011 |
Whelan KA, Reginato MJ. Surviving without oxygen: Hypoxia regulation of mammary morphogenesis and anoikis Cell Cycle. 10: 2287-2294. PMID 21670595 DOI: 10.4161/Cc.10.14.16532 |
0.733 |
|
2011 |
Lynch TP, Reginato MJ. O-GlcNAc transferase: a sweet new cancer target. Cell Cycle (Georgetown, Tex.). 10: 1712-3. PMID 21519190 DOI: 10.4161/Cc.10.11.15561 |
0.726 |
|
2011 |
Yerbes R, Palacios C, Reginato MJ, López-Rivas A. Cellular FLIP(L) plays a survival role and regulates morphogenesis in breast epithelial cells. Biochimica Et Biophysica Acta. 1813: 168-78. PMID 20951169 DOI: 10.1016/J.Bbamcr.2010.10.003 |
0.454 |
|
2011 |
Lynch TP, Jackson SR, Shahriari KS, Ferrer CM, Lazarus M, Walker S, Vosseller K, Reginato MJ. Abstract 1267: Metabolic sensor O-GlcNAc Transferase is a novel regulator of prostate cancer invasion and angiogenesis via regulation of FoxM1 Cancer Research. 71: 1267-1267. DOI: 10.1158/1538-7445.Am2011-1267 |
0.845 |
|
2010 |
Whelan KA, Caldwell SA, Shahriari KS, Jackson SR, Franchetti LD, Johannes GJ, Reginato MJ. Hypoxia suppression of Bim and Bmf blocks anoikis and luminal clearing during mammary morphogenesis. Molecular Biology of the Cell. 21: 3829-37. PMID 20861305 DOI: 10.1091/Mbc.E10-04-0353 |
0.739 |
|
2010 |
Haenssen KK, Caldwell SA, Shahriari KS, Jackson SR, Whelan KA, Klein-Szanto AJ, Reginato MJ. ErbB2 requires integrin alpha5 for anoikis resistance via Src regulation of receptor activity in human mammary epithelial cells. Journal of Cell Science. 123: 1373-82. PMID 20332114 DOI: 10.1242/Jcs.050906 |
0.784 |
|
2010 |
Caldwell SA, Jackson SR, Shahriari KS, Lynch TP, Sethi G, Walker S, Vosseller K, Reginato MJ. Nutrient sensor O-GlcNAc transferase regulates breast cancer tumorigenesis through targeting of the oncogenic transcription factor FoxM1. Oncogene. 29: 2831-42. PMID 20190804 DOI: 10.1038/Onc.2010.41 |
0.81 |
|
2008 |
Sodunke T, Reginato M, Noh H“. Micropatterned matrigel track for 3D single breast cancer cell metastasis Journal of Biotechnology. 136. DOI: 10.1016/J.Jbiotec.2008.07.250 |
0.484 |
|
2007 |
Sodunke TR, Turner KK, Caldwell SA, McBride KW, Reginato MJ, Noh HM. Micropatterns of Matrigel for three-dimensional epithelial cultures. Biomaterials. 28: 4006-16. PMID 17574663 DOI: 10.1016/J.Biomaterials.2007.05.021 |
0.371 |
|
2006 |
Reginato MJ, Muthuswamy SK. Illuminating the center: mechanisms regulating lumen formation and maintenance in mammary morphogenesis. Journal of Mammary Gland Biology and Neoplasia. 11: 205-11. PMID 17115263 DOI: 10.1007/S10911-006-9030-4 |
0.403 |
|
2005 |
Yan SR, Joseph RR, Rosen K, Reginato MJ, Jackson A, Allaire N, Brugge JS, Jobin C, Stadnyk AW. Activation of NF-kappaB following detachment delays apoptosis in intestinal epithelial cells. Oncogene. 24: 6482-91. PMID 16007176 DOI: 10.1038/Sj.Onc.1208810 |
0.577 |
|
2005 |
Reginato MJ, Mills KR, Becker EB, Lynch DK, Bonni A, Muthuswamy SK, Brugge JS. Bim regulation of lumen formation in cultured mammary epithelial acini is targeted by oncogenes. Molecular and Cellular Biology. 25: 4591-601. PMID 15899862 DOI: 10.1128/Mcb.25.11.4591-4601.2005 |
0.723 |
|
2004 |
Martin SS, Ridgeway AG, Pinkas J, Lu Y, Reginato MJ, Koh EY, Michelman M, Daley GQ, Brugge JS, Leder P. A cytoskeleton-based functional genetic screen identifies Bcl-xL as an enhancer of metastasis, but not primary tumor growth. Oncogene. 23: 4641-5. PMID 15064711 DOI: 10.1038/Sj.Onc.1207595 |
0.628 |
|
2004 |
Mills KR, Reginato M, Debnath J, Queenan B, Brugge JS. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is required for induction of autophagy during lumen formation in vitro. Proceedings of the National Academy of Sciences of the United States of America. 101: 3438-43. PMID 14993595 DOI: 10.1073/Pnas.0400443101 |
0.698 |
|
2003 |
Reginato MJ, Mills KR, Paulus JK, Lynch DK, Sgroi DC, Debnath J, Muthuswamy SK, Brugge JS. Integrins and EGFR coordinately regulate the pro-apoptotic protein Bim to prevent anoikis. Nature Cell Biology. 5: 733-40. PMID 12844146 DOI: 10.1038/Ncb1026 |
0.734 |
|
2002 |
Debnath J, Mills KR, Collins NL, Reginato MJ, Muthuswamy SK, Brugge JS. The role of apoptosis in creating and maintaining luminal space within normal and oncogene-expressing mammary acini. Cell. 111: 29-40. PMID 12372298 DOI: 10.1016/S0092-8674(02)01001-2 |
0.784 |
|
1999 |
Reginato MJ, Lazar MA. Mechanisms by which thiazolidinediones enhance insulin action Trends in Endocrinology and Metabolism. 10: 9-13. DOI: 10.1016/S1043-2760(98)00110-6 |
0.481 |
|
1998 |
Shao D, Rangwala SM, Bailey ST, Krakow SL, Reginato MJ, Lazar MA. Interdomain communication regulating ligand binding by PPAR-γ Nature. 396: 377-380. PMID 9845075 DOI: 10.1038/24634 |
0.515 |
|
1998 |
Reginato MJ, Bailey ST, Krakow SL, Minami C, Ishii S, Tanaka H, Lazar MA. A potent antidiabetic thiazolidinedione with unique peroxisome proliferator-activated receptor γ-activating properties Journal of Biological Chemistry. 273: 32679-32684. PMID 9830009 DOI: 10.1074/Jbc.273.49.32679 |
0.496 |
|
1998 |
Reginato MJ, Krakow SL, Bailey ST, Lazar MA. Prostaglandins promote and block adipogenesis through opposing effects on peroxisome proliferator-activated receptor γ Journal of Biological Chemistry. 273: 1855-1858. PMID 9442016 DOI: 10.1074/Jbc.273.4.1855 |
0.543 |
|
1997 |
Schwarz EJ, Reginato MJ, Shao D, Krakow SL, Lazar MA. Retinoic acid blocks adipogenesis by inhibiting C/EBPβ-mediated transcription Molecular and Cellular Biology. 17: 1552-1561. PMID 9032283 DOI: 10.1128/Mcb.17.3.1552 |
0.488 |
|
1997 |
Cheng X, Reginato MJ, Andrews NC, Lazar MA. The transcriptional integrator CREB-binding protein mediates positive cross talk between nuclear hormone receptors and the hematopoietic bZip protein p45/NF-E2 Molecular and Cellular Biology. 17: 1407-1416. PMID 9032267 DOI: 10.1128/Mcb.17.3.1407 |
0.496 |
|
1997 |
Adams M, Reginato MJ, Shao D, Lazar MA, Chatterjee VK. Transcriptional activation by peroxisome proliferator-activated receptor γ is inhibited by phosphorylation at a consensus mitogen-activated protein kinase site Journal of Biological Chemistry. 272: 5128-5132. PMID 9030579 DOI: 10.1074/Jbc.272.8.5128 |
0.543 |
|
1996 |
Reginato MJ, Zhang J, Lazar MA. DNA-independent and DNA-dependent mechanisms regulate the differential heterodimerization of the isoforms of the thyroid hormone receptor with retinoid X receptor Journal of Biological Chemistry. 271: 28199-28205. PMID 8910436 DOI: 10.1074/Jbc.271.45.28199 |
0.469 |
|
1995 |
Katz D, Reginato MJ, Lazar MA. Functional regulation of thyroid hormone receptor variant TRα2 by phosphorylation Molecular and Cellular Biology. 15: 2341-2348. PMID 7739517 DOI: 10.1128/Mcb.15.5.2341 |
0.509 |
|
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