Marcus Bosenberg - Publications

Affiliations: 
Yale School of Medicine Yale University, New Haven, CT 
Area:
Medicine and Surgery, Cell Biology, Oncology

103 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 McGeary MK, Damsky W, Daniels A, Song E, Micevic G, Huet-Calderwood C, Lou HJ, Paradkar S, Kaech S, Calderwood DA, Turk BE, Iwasaki A, Bosenberg MW. -loss induces type-I interferons and immune clearance of melanoma. Biorxiv : the Preprint Server For Biology. PMID 37292991 DOI: 10.1101/2023.05.23.541922  0.361
2023 Yu Y, Dai M, Huang L, Chen W, Yu E, Mendoza A, Michael H, Khanna C, Bosenberg M, McMahon M, Merlino G. PTEN phosphatase inhibits metastasis by negatively regulating the Entpd5/IGF1R pathway through ATF6. Iscience. 26: 106070. PMID 36824269 DOI: 10.1016/j.isci.2023.106070  0.314
2022 Oria VO, Zhang H, Zito CR, Rane CK, Ma XY, Provance OK, Tran TT, Adeniran A, Kluger Y, Sznol M, Bosenberg MW, Kluger HM, Jilaveanu LB. Coupled fibromodulin and SOX2 signaling as a critical regulator of metastatic outgrowth in melanoma. Cellular and Molecular Life Sciences : Cmls. 79: 377. PMID 35737114 DOI: 10.1007/s00018-022-04364-5  0.373
2021 Adams AC, Macy AM, Kang P, Castro-Ochoa KF, Wijeratne EMK, Xu YM, Liu MX, Charos A, Bosenberg MW, Gunatilaka AAL, Sertil AR, Hastings KT. Physachenolide C induces complete regression of established murine melanoma tumors via apoptosis and cell cycle arrest. Translational Oncology. 15: 101259. PMID 34735896 DOI: 10.1016/j.tranon.2021.101259  0.365
2021 Pizzurro GA, Liu C, Bridges K, Alexander AF, Huang A, Baskaran JP, Ramseier J, Bosenberg MW, Mak M, Miller-Jensen K. 3D Model of the Early Melanoma Microenvironment Captures Macrophage Transition into a Tumor-Promoting Phenotype. Cancers. 13. PMID 34572807 DOI: 10.3390/cancers13184579  0.332
2021 Giblin W, Bringman-Rodenbarger L, Guo AH, Kumar S, Monovich AC, Mostafa AM, Skinner ME, Azar M, Mady AS, Chung CH, Kadambi N, Melong KA, Lee HJ, Zhang L, Sajjakulnukit P, ... ... Bosenberg MW, et al. The deacylase SIRT5 supports melanoma viability by influencing chromatin dynamics. The Journal of Clinical Investigation. PMID 33945506 DOI: 10.1172/JCI138926  0.36
2021 Tian J, Zhang D, Kurbatov V, Wang Q, Wang Y, Fang D, Wu L, Bosenberg M, Muzumdar MD, Khan S, Lu Q, Yan Q, Lu J. 5-Fluorouracil efficacy requires anti-tumor immunity triggered by cancer-cell-intrinsic STING. The Embo Journal. e106065. PMID 33615517 DOI: 10.15252/embj.2020106065  0.313
2020 Acharya N, Madi A, Zhang H, Klapholz M, Escobar G, Dulberg S, Christian E, Ferreira M, Dixon KO, Fell G, Tooley K, Mangani D, Xia J, Singer M, Bosenberg M, et al. Endogenous Glucocorticoid Signaling Regulates CD8 T Cell Differentiation and Development of Dysfunction in the Tumor Microenvironment. Immunity. 53: 658-671.e6. PMID 32937153 DOI: 10.1016/J.Immuni.2020.08.005  0.402
2020 Alvero AB, Hanlon D, Pitruzzello M, Filler R, Robinson E, Sobolev O, Tedja R, Ventura A, Bosenberg M, Han P, Edelson RL, Mor G. Transimmunization restores immune surveillance and prevents recurrence in a syngeneic mouse model of ovarian cancer. Oncoimmunology. 9: 1758869. PMID 32566387 DOI: 10.1080/2162402X.2020.1758869  0.419
2020 Song E, Mao T, Dong H, Boisserand LSB, Antila S, Bosenberg M, Alitalo K, Thomas JL, Iwasaki A. VEGF-C-driven lymphatic drainage enables immunosurveillance of brain tumours. Nature. PMID 31942068 DOI: 10.1038/S41586-019-1912-X  0.313
2020 Scortegagna M, Hockemeyer K, Dolgalev I, Poźniak J, Rambow F, Li Y, Feng Y, Tinoco R, Otero DC, Zhang T, Brown K, Bosenberg M, Bradley LM, Marine JC, Aifantis I, et al. Siah2 control of T-regulatory cells limits anti-tumor immunity. Nature Communications. 11: 99. PMID 31911617 DOI: 10.1038/S41467-019-13826-7  0.436
2019 Svoronos AA, Bahal R, Pereira MC, Barrera FN, Deacon JC, Bosenberg M, DiMaio D, Glazer PM, Engelman DM. Tumor-Targeted, Cytoplasmic Delivery of Large, Polar Molecules using a pH-Low Insertion Peptide. Molecular Pharmaceutics. PMID 31855437 DOI: 10.1021/Acs.Molpharmaceut.9B00883  0.304
2019 Zhang H, Zhu H, Deng G, Zito CR, Oria VO, Rane CK, Zhang S, Weiss SA, Tran T, Adeniran A, Zhang F, Zhou J, Kluger Y, Bosenberg MW, Kluger HM, et al. PLEKHA5 regulates tumor growth in metastatic melanoma. Cancer. PMID 31769872 DOI: 10.1002/Cncr.32611  0.351
2019 Jiang X, Muthusamy V, Fedorova O, Kong Y, Kim DJ, Bosenberg M, Pyle AM, Iwasaki A. Intratumoral delivery of RIG-I agonist SLR14 induces robust antitumor responses. The Journal of Experimental Medicine. PMID 31601678 DOI: 10.1084/Jem.20190801  0.431
2019 Harel M, Ortenberg R, Varanasi SK, Mangalhara KC, Mardamshina M, Markovits E, Baruch EN, Tripple V, Arama-Chayoth M, Greenberg E, Shenoy A, Ayasun R, Knafo N, Xu S, Anafi L, ... ... Bosenberg M, et al. Proteomics of Melanoma Response to Immunotherapy Reveals Mitochondrial Dependence. Cell. PMID 31495571 DOI: 10.1016/J.Cell.2019.08.012  0.335
2019 Etzerodt A, Tsalkitzi K, Maniecki M, Damsky W, Delfini M, Baudoin E, Moulin M, Bosenberg M, Graversen JH, Auphan-Anezin N, Moestrup SK, Lawrence T. Specific targeting of CD163 TAMs mobilizes inflammatory monocytes and promotes T cell-mediated tumor regression. The Journal of Experimental Medicine. PMID 31375534 DOI: 10.1084/Jem.20182124  0.413
2019 Damsky W, Jilaveanu L, Turner N, Perry C, Zito C, Tomayko M, Leventhal J, Herold K, Meffre E, Bosenberg M, Kluger HM. B cell depletion or absence does not impede anti-tumor activity of PD-1 inhibitors. Journal For Immunotherapy of Cancer. 7: 153. PMID 31200747 DOI: 10.1186/S40425-019-0613-1  0.33
2019 Li Y, Tinoco R, Elmén L, Segota I, Xian Y, Fujita Y, Sahu A, Zarecki R, Marie K, Feng Y, Khateb A, Frederick DT, Ashkenazi SK, Kim H, Perez EG, ... ... Bosenberg M, et al. Gut microbiota dependent anti-tumor immunity restricts melanoma growth in Rnf5 mice. Nature Communications. 10: 1492. PMID 30940817 DOI: 10.1038/S41467-019-09525-Y  0.414
2019 Codina A, Renauer PA, Wang G, Chow RD, Park JJ, Ye H, Zhang K, Dong MB, Gassaway B, Ye L, Errami Y, Shen L, Chang A, Jain D, Herbst RS, ... Bosenberg M, et al. Convergent Identification and Interrogation of Tumor-Intrinsic Factors that Modulate Cancer Immunity In Vivo. Cell Systems. PMID 30797773 DOI: 10.1016/J.Cels.2019.01.004  0.411
2019 Blenman KRM, Wang J, Cowper S, Bosenberg M. Pathology of spontaneous and immunotherapy-induced tumor regression in a murine model of melanoma. Pigment Cell & Melanoma Research. PMID 30702217 DOI: 10.1111/Pcmr.12769  0.453
2019 Ferreira M, Krykbaeva I, Damsky W, Kluger HM, Bosenberg M. Evaluating the role of the COX2/PGE2 pathway in anti-melanoma immunity. Journal of Clinical Oncology. 37. DOI: 10.1200/Jco.2019.37.15_Suppl.E14114  0.332
2019 Edwards AK, Skobe M, Rogic A, Bosenberg M. Abstract B156: Characterization and role of CCR8+ regulatory T-cells in mouse models of malignant melanoma Cancer Immunology Research. 7. DOI: 10.1158/2326-6074.Cricimteatiaacr18-B156  0.45
2019 Krykbaeva I, Damsky W, Turner N, Perry C, Kluger H, Bosenberg M. LB1122 Myeloid targeting in combination with PD1 inhibition boosts anti-tumor immunity in melanoma Journal of Investigative Dermatology. 139. DOI: 10.1016/J.Jid.2019.06.089  0.356
2018 Gupta K, Levinsohn J, Linderman G, Chen D, Sun TY, Dong D, Taketo MM, Bosenberg M, Kluger Y, Choate K, Myung P. Single-Cell Analysis Reveals a Hair Follicle Dermal Niche Molecular Differentiation Trajectory that Begins Prior to Morphogenesis. Developmental Cell. PMID 30595533 DOI: 10.1016/J.Devcel.2018.11.032  0.301
2018 Theodosakis N, Langdon CG, Micevic G, Krykbaeva I, Means RE, Stern DF, Bosenberg MW. Inhibition of isoprenylation synergizes with MAPK blockade to prevent growth in treatment-resistant melanoma, colorectal, and lung cancer. Pigment Cell & Melanoma Research. PMID 30281931 DOI: 10.1111/Pcmr.12742  0.3
2018 Ventura A, Vassall A, Robinson E, Filler R, Hanlon D, Meeth K, Ezaldein H, Girardi M, Sobolev O, Bosenberg MW, Edelson RL. Extracorporeal Photochemotherapy Drives Monocyte-to-Dendritic Cell Maturation to Induce Anti-Cancer Immunity. Cancer Research. PMID 29764863 DOI: 10.1158/0008-5472.Can-18-0171  0.314
2018 Turner N, Ware O, Bosenberg M. Genetics of metastasis: melanoma and other cancers. Clinical & Experimental Metastasis. PMID 29722002 DOI: 10.1007/S10585-018-9893-Y  0.402
2018 Perry CJ, Muñoz-Rojas AR, Meeth KM, Kellman LN, Amezquita RA, Thakral D, Du VY, Wang JX, Damsky W, Kuhlmann AL, Sher JW, Bosenberg M, Miller-Jensen K, Kaech SM. Myeloid-targeted immunotherapies act in synergy to induce inflammation and antitumor immunity. The Journal of Experimental Medicine. PMID 29436395 DOI: 10.1084/Jem.20171435  0.395
2018 Xiao Q, Wu J, Wang WJ, Chen S, Zheng Y, Yu X, Meeth K, Sahraei M, Bothwell ALM, Chen L, Bosenberg M, Chen J, Sexl V, Sun L, Li L, et al. DKK2 imparts tumor immunity evasion through β-catenin-independent suppression of cytotoxic immune-cell activation. Nature Medicine. PMID 29431745 DOI: 10.1038/Nm.4496  0.448
2018 Turner N, Damsky W, Wang J, Meeth K, Blenman K, Bosenberg M. 1245 PD-1 blockade impedes tumor growth in the immunogenic YUMMER1.7 mouse melanoma model Journal of Investigative Dermatology. 138. DOI: 10.1016/J.Jid.2018.03.1260  0.36
2017 Pan W, Zhu S, Qu K, Meeth K, Cheng J, He K, Ma H, Liao Y, Wen X, Roden C, Tobiasova Z, Wei Z, Zhao J, Liu J, Zheng J, ... ... Bosenberg M, et al. The DNA Methylcytosine Dioxygenase Tet2 Sustains Immunosuppressive Function of Tumor-Infiltrating Myeloid Cells to Promote Melanoma Progression. Immunity. 47: 284-297.e5. PMID 28813659 DOI: 10.1016/J.Immuni.2017.07.020  0.456
2017 Damsky WE, Bosenberg M. Melanocytic nevi and melanoma: unraveling a complex relationship. Oncogene. 36: 5771-5792. PMID 28604751 DOI: 10.1038/Onc.2017.189  0.412
2017 Wang J, Perry CJ, Meeth K, Thakral D, Damsky W, Micevic G, Kaech S, Blenman K, Bosenberg M. UV-induced somatic mutations elicit a functional T cell response in the YUMMER1.7 Mouse Melanoma Model. Pigment Cell & Melanoma Research. PMID 28379630 DOI: 10.1111/Pcmr.12591  0.428
2017 Lazova R, Pornputtapong N, Halaban R, Bosenberg M, Bai Y, Chai H, Krauthammer M. Spitz nevi and Spitzoid melanomas: exome sequencing and comparison with conventional melanocytic nevi and melanomas. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 28186096 DOI: 10.1038/Modpathol.2016.237  0.346
2017 Damsky W, Wang J, Perry C, Meeth K, Kaech S, Bosenberg M. 766 Exposure to ultraviolet light enhances anti-tumor immunity and response to immunotherapy in a mouse model of melanoma Journal of Investigative Dermatology. 137: S132. DOI: 10.1016/J.Jid.2017.02.791  0.372
2017 Micevic G, Muthusamy V, Pupo G, Scolyer R, Long G, Bosenberg M. (S029) Development of an Immune-Associated Molecular Signature Predicting Melanoma Survival International Journal of Radiation Oncology Biology Physics. 98. DOI: 10.1016/J.Ijrobp.2017.02.065  0.305
2016 Cohen JV, Tawbi H, Margolin KA, Amravadi R, Bosenberg M, Brastianos PK, Chiang VL, de Groot J, Glitza IC, Herlyn M, Holmen SL, Jilaveanu LB, Lassman A, Moschos S, Postow MA, et al. Melanoma Central Nervous System Metastases: Current Approaches, Challenges, and Opportunities. Pigment Cell & Melanoma Research. PMID 27615400 DOI: 10.1111/Pcmr.12538  0.346
2016 Srisuttiyakorn C, Bulloch K, Rodic N, Bosenberg M, Ariyan S, Narayan D, Gould Rothberg BE, Galan A. Intratumoral multinucleated giant cells are not a prognostic pathologic feature in cutaneous melanoma. Journal of Cutaneous Pathology. PMID 27246995 DOI: 10.1111/Cup.12750  0.383
2016 Claps G, Cheli Y, Zhang T, Scortegagna M, Lau E, Kim H, Qi J, Li JL, James B, Dzung A, Levesque MP, Dummer R, Hayward NK, Bosenberg M, Brown KM, et al. A Transcriptionally Inactive ATF2 Variant Drives Melanomagenesis. Cell Reports. PMID 27210757 DOI: 10.1016/J.Celrep.2016.04.072  0.476
2016 Ngiow SF, Meeth KM, Stannard K, Barkauskas DS, Bollag G, Bosenberg M, Smyth MJ. Co-inhibition of colony stimulating factor-1 receptor and BRAF oncogene in mouse models of BRAF(V600E) melanoma. Oncoimmunology. 5: e1089381. PMID 27141346 DOI: 10.1080/2162402X.2015.1089381  0.432
2016 Salmon H, Idoyaga J, Rahman A, Leboeuf M, Remark R, Jordan S, Casanova-Acebes M, Khudoynazarova M, Agudo J, Tung N, Chakarov S, Rivera C, Hogstad B, Bosenberg M, Hashimoto D, et al. Expansion and Activation of CD103(+) Dendritic Cell Progenitors at the Tumor Site Enhances Tumor Responses to Therapeutic PD-L1 and BRAF Inhibition. Immunity. 44: 924-38. PMID 27096321 DOI: 10.1016/J.Immuni.2016.03.012  0.378
2016 Kaur A, Webster MR, Marchbank K, Behera R, Ndoye A, Kugel CH, Dang VM, Appleton J, O'Connell MP, Cheng P, Valiga AA, Morissette R, McDonnell NB, Ferrucci L, Kossenkov AV, ... ... Bosenberg M, et al. sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance. Nature. PMID 27042933 DOI: 10.1038/Nature17392  0.374
2016 Micevic G, Muthusamy V, Damsky W, Theodosakis N, Liu X, Meeth K, Wingrove E, Santhanakrishnan M, Bosenberg M. DNMT3b Modulates Melanoma Growth by Controlling Levels of mTORC2 Component RICTOR. Cell Reports. PMID 26923591 DOI: 10.1016/J.Celrep.2016.02.010  0.431
2016 Peng W, Chen JQ, Liu C, Malu S, Creasy C, Tetzlaff M, Xu C, McKenzie J, Zhang C, Liang X, Williams L, Deng W, Chen G, Mbofung R, Lazar A, ... ... Bosenberg M, et al. Abstract 4363: Loss of PTEN promotes resistance to T cell-mediated immunotherapy Cancer Research. 76: 4363-4363. DOI: 10.1158/1538-7445.Am2016-4363  0.451
2016 Ventura A, Vassall A, Robinson E, Bosenberg M, Bianchi L, Chimenti S, Edelson R. 469 Experimental T cells immunotherapy by tumor-loaded ECP-generated dendritic antigen presenting cells Journal of Investigative Dermatology. 136. DOI: 10.1016/J.Jid.2016.06.491  0.332
2016 Wang J, Meeth K, Perry C, Ventura A, Kaech S, Edelson R, Bosenberg M. 616 UV-induced somatic mutations elicit a functional T cell response and tumor regression in BRAF V600E , CDKN2A -/- , PTEN -/- melanoma model Journal of Investigative Dermatology. 136: S109. DOI: 10.1016/J.Jid.2016.02.656  0.402
2016 Khalil D, Ventura A, Vassal A, Han P, Meeth K, Wang J, Filler R, Robinson E, Hanlon DJ, Bosenberg M, Edelson R. 275 Experimental ECP initiation of selective anti-tumor immunity Journal of Investigative Dermatology. 136. DOI: 10.1016/J.Jid.2016.02.305  0.337
2015 Feng Y, Pinkerton AB, Hulea L, Zhang T, Davies MA, Grotegut S, Cheli Y, Yin H, Lau E, Kim H, De SK, Barile E, Pellecchia M, Bosenberg M, Li JL, et al. SBI-0640756 Attenuates the Growth of Clinically Unresponsive Melanomas by Disrupting the eIF4F Translation Initiation Complex. Cancer Research. PMID 26603897 DOI: 10.1158/0008-5472.Can-15-0885  0.396
2015 Krauthammer M, Kong Y, Bacchiocchi A, Evans P, Pornputtapong N, Wu C, McCusker JP, Ma S, Cheng E, Straub R, Serin M, Bosenberg M, Ariyan S, Narayan D, Sznol M, et al. Exome sequencing identifies recurrent mutations in NF1 and RASopathy genes in sun-exposed melanomas. Nature Genetics. PMID 26214590 DOI: 10.1038/Ng.3361  0.34
2015 Marzuka A, Huang L, Theodosakis N, Bosenberg M. Melanoma Treatments: Advances and Mechanisms. Journal of Cellular Physiology. PMID 25899612 DOI: 10.1002/Jcp.25019  0.407
2015 Mann MB, Black MA, Jones DJ, Ward JM, Yew CC, Newberg JY, Dupuy AJ, Rust AG, Bosenberg MW, McMahon M, Print CG, Copeland NG, Jenkins NA. Transposon mutagenesis identifies genetic drivers of Braf(V600E) melanoma. Nature Genetics. 47: 486-95. PMID 25848750 DOI: 10.1038/Ng.3275  0.307
2015 Lau E, Sedy J, Sander C, Shaw MA, Feng Y, Scortegagna M, Claps G, Robinson S, Cheng P, Srivas R, Soonthornvacharin S, Ideker T, Bosenberg M, Gonzalez R, Robinson W, et al. Transcriptional repression of IFNβ1 by ATF2 confers melanoma resistance to therapy. Oncogene. PMID 25728676 DOI: 10.1038/Onc.2015.22  0.385
2015 Scortegagna M, Lau E, Zhang T, Feng Y, Sereduk C, Yin H, De SK, Meeth K, Platt JT, Langdon CG, Halaban R, Pellecchia M, Davies MA, Brown K, Stern DF, ... Bosenberg M, et al. PDK1 and SGK3 Contribute to the Growth of BRAF-Mutant Melanomas and Are Potential Therapeutic Targets. Cancer Research. 75: 1399-412. PMID 25712345 DOI: 10.1158/0008-5472.Can-14-2785  0.455
2015 Perna D, Karreth FA, Rust AG, Perez-Mancera PA, Rashid M, Iorio F, Alifrangis C, Arends MJ, Bosenberg MW, Bollag G, Tuveson DA, Adams DJ. BRAF inhibitor resistance mediated by the AKT pathway in an oncogenic BRAF mouse melanoma model. Proceedings of the National Academy of Sciences of the United States of America. 112: E536-45. PMID 25624498 DOI: 10.1073/Pnas.1418163112  0.32
2015 Damsky W, Micevic G, Meeth K, Muthusamy V, Curley DP, Santhanakrishnan M, Erdelyi I, Platt JT, Huang L, Theodosakis N, Zaidi MR, Tighe S, Davies MA, Dankort D, McMahon M, ... ... Bosenberg M, et al. mTORC1 activation blocks BrafV600E-induced growth arrest but is insufficient for melanoma formation. Cancer Cell. 27: 41-56. PMID 25584893 DOI: 10.1016/J.Ccell.2014.11.014  0.4
2015 Acquavella N, Clever D, Yu Z, Roelke-Parker M, Palmer DC, Xi L, Pflicke H, Ji Y, Gros A, Hanada K, Goldlust IS, Mehta GU, Klebanoff CA, Crompton JG, Sukumar M, ... ... Bosenberg MW, et al. Type I cytokines synergize with oncogene inhibition to induce tumor growth arrest. Cancer Immunology Research. 3: 37-47. PMID 25358764 DOI: 10.1158/2326-6066.Cir-14-0122  0.341
2015 Kaur A, Marchbank K, Dang V, O'Connell M, Webster M, Appleton J, Cheng P, Valiga A, Morissette R, McDonnell N, Ferrucci L, Kossenkov A, Meeth K, Bosenberg M, Tang H, et al. Abstract A04: Aging microenvironment modulates melanoma invasion and metastasis Cancer Research. 75. DOI: 10.1158/1538-7445.Mel2014-A04  0.378
2015 Meeth KM, Damsky WE, Bosenberg M. Abstract 5141: A comprehensive system of congenic mouse melanoma models for evaluation of immune therapies Cancer Research. 75: 5141-5141. DOI: 10.1158/1538-7445.Am2015-5141  0.435
2014 Steinberg SM, Zhang P, Malik BT, Boni A, Shabaneh TB, Byrne KT, Mullins DW, Brinckerhoff CE, Ernstoff MS, Bosenberg MW, Turk MJ. BRAF inhibition alleviates immune suppression in murine autochthonous melanoma. Cancer Immunology Research. 2: 1044-50. PMID 25183499 DOI: 10.1158/2326-6066.Cir-14-0074  0.322
2014 Zhou Y, Rideout WM, Bressel A, Yalavarthi S, Zi T, Potz D, Farlow S, Brodeur J, Monti A, Reddipalli S, Xiao Q, Bottega S, Feng B, Chiu MI, Bosenberg M, et al. Spontaneous genomic alterations in a chimeric model of colorectal cancer enable metastasis and guide effective combinatorial therapy. Plos One. 9: e105886. PMID 25162504 DOI: 10.1371/Journal.Pone.0105886  0.411
2014 Theodosakis N, Micevic G, Kelly DP, Bosenberg M. Mitochondrial function in melanoma. Archives of Biochemistry and Biophysics. 563: 56-9. PMID 24997363 DOI: 10.1016/J.Abb.2014.06.028  0.371
2014 Luo X, Mitra D, Sullivan RJ, Wittner BS, Kimura AM, Pan S, Hoang MP, Brannigan BW, Lawrence DP, Flaherty KT, Sequist LV, McMahon M, Bosenberg MW, Stott SL, Ting DT, et al. Isolation and molecular characterization of circulating melanoma cells. Cell Reports. 7: 645-53. PMID 24746818 DOI: 10.1016/J.Celrep.2014.03.039  0.354
2014 Ho PC, Meeth KM, Tsui YC, Srivastava B, Bosenberg MW, Kaech SM. Immune-based antitumor effects of BRAF inhibitors rely on signaling by CD40L and IFNγ. Cancer Research. 74: 3205-17. PMID 24736544 DOI: 10.1158/0008-5472.Can-13-3461  0.315
2014 Bosenberg M, Arnheiter H, Kelsh R. Melanoma in mankind's best friend. Pigment Cell & Melanoma Research. 27: 1. PMID 24344626 DOI: 10.1111/Pcmr.12196  0.3
2014 Scortegagna M, Ruller C, Feng Y, Lazova R, Kluger H, Li JL, De SK, Rickert R, Pellecchia M, Bosenberg M, Ronai ZA. Genetic inactivation or pharmacological inhibition of Pdk1 delays development and inhibits metastasis of Braf(V600E)::Pten(-/-) melanoma. Oncogene. 33: 4330-9. PMID 24037523 DOI: 10.1038/Onc.2013.383  0.405
2014 Damsky WE, Theodosakis N, Bosenberg M. Melanoma metastasis: new concepts and evolving paradigms. Oncogene. 33: 2413-2422. PMID 23728340 DOI: 10.1038/Onc.2013.194  0.439
2014 Scortegagna M, Ruller C, Feng Y, Lazova R, Kluger H, Li J, De SK, Rickert R, Pellecchia M, Bosenberg M, Ronai Z. Abstract 59: PDK1 in melanoma development and metastasis Cancer Research. 74: 59-59. DOI: 10.1158/1538-7445.Am2014-59  0.48
2014 Varsano T, Feng Y, Claps G, Scortegagna M, Lau E, Leonard M, Pinkerton A, Pellecchia M, Davies M, Bosenberg M, Ronai Z. Abstract 4520: Inhibition of melanoma growth by small molecules that attenuate PI3K/PDK1 signaling and promote ATF2 mitochondrial localization Cancer Research. 74: 4520-4520. DOI: 10.1158/1538-7445.Am2014-4520  0.402
2013 Marsh Durban V, Deuker MM, Bosenberg MW, Phillips W, McMahon M. Differential AKT dependency displayed by mouse models of BRAFV600E-initiated melanoma. The Journal of Clinical Investigation. 123: 5104-18. PMID 24200692 DOI: 10.1172/Jci69619  0.351
2013 Yuan P, Ito K, Perez-Lorenzo R, Del Guzzo C, Lee JH, Shen CH, Bosenberg MW, McMahon M, Cantley LC, Zheng B. Phenformin enhances the therapeutic benefit of BRAF(V600E) inhibition in melanoma. Proceedings of the National Academy of Sciences of the United States of America. 110: 18226-31. PMID 24145418 DOI: 10.1073/Pnas.1317577110  0.35
2013 Tworkoski KA, Platt JT, Bacchiocchi A, Bosenberg M, Boggon TJ, Stern DF. MERTK controls melanoma cell migration and survival and differentially regulates cell behavior relative to AXL. Pigment Cell & Melanoma Research. 26: 527-41. PMID 23617806 DOI: 10.1111/Pcmr.12110  0.407
2013 Muthusamy V, Premi S, Soper C, Platt J, Bosenberg M. The hematopoietic stem cell regulatory gene latexin has tumor-suppressive properties in malignant melanoma. The Journal of Investigative Dermatology. 133: 1827-33. PMID 23364479 DOI: 10.1038/Jid.2013.48  0.452
2013 Baird JR, Byrne KT, Lizotte PH, Toraya-Brown S, Scarlett UK, Alexander MP, Sheen MR, Fox BA, Bzik DJ, Bosenberg M, Mullins DW, Turk MJ, Fiering S. Immune-mediated regression of established B16F10 melanoma by intratumoral injection of attenuated Toxoplasma gondii protects against rechallenge. Journal of Immunology (Baltimore, Md. : 1950). 190: 469-78. PMID 23225891 DOI: 10.4049/Jimmunol.1201209  0.413
2013 Feng Y, Lau E, Scortegagna M, Ruller C, De SK, Barile E, Krajewski S, Aza-Blanc P, Williams R, Pinkerton AB, Jackson M, Chin L, Pellecchia M, Bosenberg M, Ronai ZA. Inhibition of melanoma development in the Nras((Q61K)) ::Ink4a(-/-) mouse model by the small molecule BI-69A11. Pigment Cell & Melanoma Research. 26: 136-42. PMID 23035722 DOI: 10.1111/Pcmr.12033  0.381
2013 McMahon M, Thakur MD, Marsh V, Silva J, Landman A, Deuker M, Salangsang F, Pryer N, Phillips W, Levesque M, Dummer R, Bosenberg M, Sellers WR, Stuart D. Abstract SY17-03: Targeting BRAF and PI3′-kinase signaling for therapy of melanoma. Cancer Research. 73. DOI: 10.1158/1538-7445.Am2013-Sy17-03  0.452
2013 Zhou Y, Rideout WM, Bressel A, Yalavarthi S, Zi T, Monti A, Bottega S, Feng B, Chiu MI, Bosenberg M, Heyer J. Abstract 2737: Spontaneous genomic alterations identified in a chimeric model of colorectal cancer guide effective combinatorial therapy. Cancer Research. 73: 2737-2737. DOI: 10.1158/1538-7445.Am2013-2737  0.415
2012 Krauthammer M, Kong Y, Ha BH, Evans P, Bacchiocchi A, McCusker JP, Cheng E, Davis MJ, Goh G, Choi M, Ariyan S, Narayan D, Dutton-Regester K, Capatana A, Holman EC, ... Bosenberg M, et al. Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma. Nature Genetics. 44: 1006-14. PMID 22842228 DOI: 10.1038/Ng.2359  0.378
2012 Smalley KS, Aplin AE, Flaherty KT, Hoeller C, Bosserhoff AK, Haass NK, Bosenberg M, Ribas A, Barnhill R, Kudchadkar R, Messina JL. Meeting report from the 2011 International Melanoma Congress, Tampa, Florida. Pigment Cell & Melanoma Research. 25: E1-11. PMID 22117673 DOI: 10.1111/J.1755-148X.2011.00943.X  0.311
2012 Marzuka A, Bosenberg M. Abstract 2822: Characterization of the effects of PLX4720 in the immunocompetent BRAF/PTEN mouse melanoma model Cancer Research. 72: 2822-2822. DOI: 10.1158/1538-7445.Am2012-2822  0.411
2011 Damsky WE, Curley DP, Santhanakrishnan M, Rosenbaum LE, Platt JT, Gould Rothberg BE, Taketo MM, Dankort D, Rimm DL, McMahon M, Bosenberg M. β-catenin signaling controls metastasis in Braf-activated Pten-deficient melanomas. Cancer Cell. 20: 741-54. PMID 22172720 DOI: 10.1016/J.Ccr.2011.10.030  0.736
2011 Liu S, Yu H, Kumar SM, Martin JS, Bing Z, Sheng W, Bosenberg M, Xu X. Norcantharidin induces melanoma cell apoptosis through activation of TR3 dependent pathway. Cancer Biology & Therapy. 12: 1005-14. PMID 22123174 DOI: 10.4161/Cbt.12.11.18380  0.412
2011 Scott KL, Nogueira C, Heffernan TP, van Doorn R, Dhakal S, Hanna JA, Min C, Jaskelioff M, Xiao Y, Wu CJ, Cameron LA, Perry SR, Zeid R, Feinberg T, Kim M, ... ... Bosenberg M, et al. Proinvasion metastasis drivers in early-stage melanoma are oncogenes. Cancer Cell. 20: 92-103. PMID 21741599 DOI: 10.1016/J.Ccr.2011.05.025  0.438
2011 Tworkoski K, Singhal G, Szpakowski S, Zito CI, Bacchiocchi A, Muthusamy V, Bosenberg M, Krauthammer M, Halaban R, Stern DF. Phosphoproteomic screen identifies potential therapeutic targets in melanoma. Molecular Cancer Research : McR. 9: 801-12. PMID 21521745 DOI: 10.1158/1541-7786.Mcr-10-0512  0.336
2011 Damsky WE, Bosenberg M. Unwelcome guests: macrophages promote UV-induced melanoma. Pigment Cell & Melanoma Research. 24: 265-7. PMID 21513010 DOI: 10.1111/J.1755-148X.2011.00833.X  0.32
2011 Rosenbaum LE, Damsky WE, Bosenberg M. Abstract 3377: The effect of E-cadherin loss on melanoma formation and metastasis in a conditional mouse model Cancer Research. 71: 3377-3377. DOI: 10.1158/1538-7445.Am2011-3377  0.739
2010 Damsky WE, Rosenbaum LE, Bosenberg M. Decoding melanoma metastasis. Cancers. 3: 126-63. PMID 24212610 DOI: 10.3390/Cancers3010126  0.743
2010 Shah M, Bhoumik A, Goel V, Dewing A, Breitwieser W, Kluger H, Krajewski S, Krajewska M, Dehart J, Lau E, Kallenberg DM, Jeong H, Eroshkin A, Bennett DC, Chin L, ... Bosenberg M, et al. A role for ATF2 in regulating MITF and melanoma development. Plos Genetics. 6: e1001258. PMID 21203491 DOI: 10.1371/Journal.Pgen.1001258  0.427
2010 Damsky WE, Bosenberg M. Mouse melanoma models and cell lines. Pigment Cell & Melanoma Research. 23: 853-9. PMID 20973935 DOI: 10.1111/J.1755-148X.2010.00777.X  0.333
2010 Ferguson B, Konrad Muller H, Handoko HY, Khosrotehrani K, Beermann F, Hacker E, Soyer HP, Bosenberg M, Walker GJ. Differential roles of the pRb and Arf/p53 pathways in murine naevus and melanoma genesis. Pigment Cell & Melanoma Research. 23: 771-80. PMID 20718941 DOI: 10.1111/J.1755-148X.2010.00752.X  0.374
2010 Nogueira C, Kim KH, Sung H, Paraiso KH, Dannenberg JH, Bosenberg M, Chin L, Kim M. Cooperative interactions of PTEN deficiency and RAS activation in melanoma metastasis. Oncogene. 29: 6222-32. PMID 20711233 DOI: 10.1038/Onc.2010.349  0.371
2010 Held M, Bosenberg M. A role for the JARID1B stem cell marker for continuous melanoma growth. Pigment Cell & Melanoma Research. 23: 481-3. PMID 20546534 DOI: 10.1111/J.1755-148X.2010.00726.X  0.309
2010 Kabbarah O, Nogueira C, Feng B, Nazarian RM, Bosenberg M, Wu M, Scott KL, Kwong LN, Xiao Y, Cordon-Cardo C, Granter SR, Ramaswamy S, Golub T, Duncan LM, Wagner SN, et al. Integrative genome comparison of primary and metastatic melanomas. Plos One. 5: e10770. PMID 20520718 DOI: 10.1371/Journal.Pone.0010770  0.4
2010 Tonks ID, Mould AW, Schroder WA, Hacker E, Bosenberg M, Hayward NK, Walker GJ, Kay GF. Melanocyte homeostasis in vivo tolerates Rb1 loss in a developmentally independent fashion. Pigment Cell & Melanoma Research. 23: 564-70. PMID 20518858 DOI: 10.1111/J.1755-148X.2010.00722.X  0.346
2010 Zhou Y, Rideout WM, Zi T, Bressel A, Reddypalli S, Rancourt R, Woo JK, Horner JW, Chin L, Chiu MI, Bosenberg M, Jacks T, Clark SC, Depinho RA, Robinson MO, et al. Chimeric mouse tumor models reveal differences in pathway activation between ERBB family- and KRAS-dependent lung adenocarcinomas. Nature Biotechnology. 28: 71-8. PMID 20023657 DOI: 10.1038/Nbt.1595  0.421
2010 Nogueira C, Kim KH, Paraiso KT, Dannenberg J, Bosenberg M, Chin L, Kim M. Abstract LB-154: Loss of PTEN cooperates with activated RAS in melanoma genesis and progression Cancer Research. 70. DOI: 10.1158/1538-7445.Am10-Lb-154  0.381
2009 Dankort D, Curley DP, Cartlidge RA, Nelson B, Karnezis AN, Damsky WE, You MJ, DePinho RA, McMahon M, Bosenberg M. Braf(V600E) cooperates with Pten loss to induce metastatic melanoma. Nature Genetics. 41: 544-52. PMID 19282848 DOI: 10.1038/Ng.356  0.467
2008 Smalley KS, Contractor R, Nguyen TK, Xiao M, Edwards R, Muthusamy V, King AJ, Flaherty KT, Bosenberg M, Herlyn M, Nathanson KL. Identification of a novel subgroup of melanomas with KIT/cyclin-dependent kinase-4 overexpression. Cancer Research. 68: 5743-52. PMID 18632627 DOI: 10.1158/0008-5472.Can-08-0235  0.411
2008 Gurumurthy S, Hezel AF, Sahin E, Berger JH, Bosenberg MW, Bardeesy N. LKB1 deficiency sensitizes mice to carcinogen-induced tumorigenesis. Cancer Research. 68: 55-63. PMID 18172296 DOI: 10.1158/0008-5472.CAN-07-3225  0.327
2006 Muthusamy V, Duraisamy S, Bradbury CM, Hobbs C, Curley DP, Nelson B, Bosenberg M. Epigenetic silencing of novel tumor suppressors in malignant melanoma. Cancer Research. 66: 11187-93. PMID 17145863 DOI: 10.1158/0008-5472.Can-06-1274  0.428
2006 Kim WY, Safran M, Buckley MRM, Ebert BL, Glickman J, Bosenberg M, Regan M, Kaelin WG. Failure to prolyl hydroxylate hypoxia-inducible factor α phenocopies VHL inactivation in vivo Embo Journal. 25: 4650-4662. PMID 16977322 DOI: 10.1038/Sj.Emboj.7601300  0.316
2006 Bosenberg M, Muthusamy V, Curley DP, Wang Z, Hobbs C, Nelson B, Nogueira C, Horner JW, Depinho R, Chin L. Characterization of melanocyte-specific inducible Cre recombinase transgenic mice. Genesis (New York, N.Y. : 2000). 44: 262-7. PMID 16676322 DOI: 10.1002/Dvg.20205  0.348
2004 Stahl JM, Sharma A, Cheung M, Zimmerman M, Cheng JQ, Bosenberg MW, Kester M, Sandirasegarane L, Robertson GP. Deregulated Akt3 activity promotes development of malignant melanoma. Cancer Research. 64: 7002-10. PMID 15466193 DOI: 10.1158/0008-5472.Can-04-1399  0.366
2001 Krop IE, Sgroi D, Porter DA, Lunetta KL, LeVangie R, Seth P, Kaelin CM, Rhei E, Bosenberg M, Schnitt S, Marks JR, Pagon Z, Belina D, Razumovic J, Polyak K. HIN-1, a putative cytokine highly expressed in normal but not cancerous mammary epithelial cells. Proceedings of the National Academy of Sciences of the United States of America. 98: 9796-801. PMID 11481438 DOI: 10.1073/Pnas.171138398  0.337
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