Yvonne Janssen-Heininger - Publications

Affiliations: 
Cellular, Molecular and Biomedical Sciences The University of Vermont and State Agricultural College 
Area:
Cell Biology, Pathology

93 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Cruz LC, Habibovic A, Dempsey B, Massafera MP, Janssen-Heininger YMW, Lin MJ, Hoffman ET, Weiss DJ, Huang SK, van der Vliet A, Meotti FC. Identification of tyrosine brominated extracellular matrix proteins in normal and fibrotic lung tissues. Redox Biology. 71: 103102. PMID 38430684 DOI: 10.1016/j.redox.2024.103102  0.305
2022 Corteselli E, Aboushousha R, Janssen-Heininger Y. -Glutathionylation-Controlled Apoptosis of Lung Epithelial Cells; Potential Implications for Lung Fibrosis. Antioxidants (Basel, Switzerland). 11. PMID 36139863 DOI: 10.3390/antiox11091789  0.389
2022 Morris CR, Habibovic A, Dustin CM, Schiffers C, Lin MC, Ather JL, Janssen-Heininger YMW, Poynter ME, Utermohlen O, Krönke M, van der Vliet A. Macrophage-intrinsic DUOX1 contributes to type 2 inflammation and mucus metaplasia during allergic airway disease. Mucosal Immunology. PMID 35654836 DOI: 10.1038/s41385-022-00530-x  0.355
2021 van de Wetering C, Manuel AM, Sharafi M, Aboushousha R, Qian X, Erickson C, MacPherson M, Chan G, Adcock IM, ZounematKermani N, Schleich F, Louis R, Bohrnsen E, D'Alessandro A, Wouters EF, ... ... Janssen-Heininger YM, et al. Glutathione-S-transferase P promotes glycolysis in asthma in association with oxidation of pyruvate kinase M2. Redox Biology. 47: 102160. PMID 34624602 DOI: 10.1016/j.redox.2021.102160  0.311
2021 van de Wetering C, Elko E, Berg M, Schiffers CHJ, Stylianidis V, van den Berge M, Nawijn MC, Wouters EFM, Janssen-Heininger YMW, Reynaert NL. Glutathione S-transferases and their implications in the lung diseases asthma and chronic obstructive pulmonary disease: Early life susceptibility? Redox Biology. 43: 101995. PMID 33979767 DOI: 10.1016/j.redox.2021.101995  0.378
2021 Aboushousha R, Elko E, Chia SB, Manuel AM, van de Wetering C, van der Velden J, MacPherson M, Erickson C, Reisz JA, D'Alessandro A, Wouters EFM, Reynaert NL, Lam YW, Anathy V, van der Vliet A, ... ... Janssen-Heininger YMW, et al. Glutathionylation chemistry promotes interleukin-1 beta-mediated glycolytic reprogramming and pro-inflammatory signaling in lung epithelial cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 35: e21525. PMID 33817836 DOI: 10.1096/fj.202002687RR  0.312
2020 Chia SB, Nolin JD, Aboushousha R, Erikson C, Irvin CG, Poynter ME, van der Velden J, Taatjes DJ, van der Vliet A, Anathy V, Janssen-Heininger YMW. Glutaredoxin deficiency promotes activation of the transforming growth factor beta pathway in airway epithelial cells, in association with fibrotic airway remodeling. Redox Biology. 37: 101720. PMID 32971362 DOI: 10.1016/j.redox.2020.101720  0.414
2020 Zhang J, Ye ZW, Janssen-Heininger Y, Townsend DM, Tew KD. Development of Telintra as an Inhibitor of Glutathione S-Transferase P. Handbook of Experimental Pharmacology. PMID 32767141 DOI: 10.1007/164_2020_392  0.313
2020 Janssen-Heininger Y, Reynaert NL, van der Vliet A, Anathy V. Endoplasmic reticulum stress and glutathione therapeutics in chronic lung diseases. Redox Biology. 101516. PMID 32249209 DOI: 10.1016/J.Redox.2020.101516  0.379
2020 van der Velden JL, Alcorn JF, Chapman DG, Lundblad LKA, Irvin CG, Davis RJ, Butnor K, Janssen-Heininger YMW. Airway epithelial specific deletion of Jun-N-terminal kinase 1 attenuates pulmonary fibrosis in two independent mouse models. Plos One. 15: e0226904. PMID 31935227 DOI: 10.1371/Journal.Pone.0226904  0.394
2020 van de Wetering C, Aboushousha R, Manuel AM, Chia SB, Erickson C, MacPherson MB, van der Velden JL, Anathy V, Dixon AE, Irvin CG, Poynter ME, van der Vliet A, Wouters EFM, Reynaert NL, Janssen-Heininger YMW. Pyruvate Kinase M2 Promotes Expression of Proinflammatory Mediators in House Dust Mite-Induced Allergic Airways Disease. Journal of Immunology (Baltimore, Md. : 1950). PMID 31924651 DOI: 10.4049/Jimmunol.1901086  0.371
2019 Chia SB, Elko EA, Aboushousha R, Manuel AM, van de Wetering C, Druso JE, van der Velden J, Seward DJ, Anathy V, Irvin CG, Lam YW, van der Vliet A, Janssen-Heininger Y. Dysregulation of the glutaredoxin/S-glutathionylation redox axis in lung diseases. American Journal of Physiology. Cell Physiology. PMID 31693398 DOI: 10.1152/ajpcell.00410.2019  0.339
2018 van der Vliet A, Janssen-Heininger YMW, Anathy V. Oxidative stress in chronic lung disease: From mitochondrial dysfunction to dysregulated redox signaling. Molecular Aspects of Medicine. PMID 30098327 DOI: 10.1016/j.mam.2018.08.001  0.353
2018 Anathy V, Lahue KG, Chapman DG, Chia SB, Casey DT, Aboushousha R, van der Velden JLJ, Elko E, Hoffman SM, McMillan DH, Jones JT, Nolin JD, Abdalla S, Schneider R, Seward DJ, ... ... Janssen-Heininger YMW, et al. Reducing protein oxidation reverses lung fibrosis. Nature Medicine. PMID 29988126 DOI: 10.1038/S41591-018-0090-Y  0.77
2018 van der Velden JL, Wagner DE, Lahue KG, Abdalla ST, Lam YW, Weiss DJ, Janssen-Heininger YMW. TGF-β1-induced deposition of provisional extracellular matrix by tracheal basal cells promotes epithelial-to-mesenchymal transition in a JNK1-dependent manner. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 29469614 DOI: 10.1152/Ajplung.00053.2017  0.362
2018 Tsukahara Y, Pérez BF, Yang H, Janssen-Heininger Y, Bachschmid M, Matsui R. Redox control of liver fibrosis in aged mice Free Radical Biology and Medicine. 128. DOI: 10.1016/J.Freeradbiomed.2018.10.317  0.348
2018 Janssen-Heininger Y, Kinsey M, Chia SB, Peng Z, Lahue K, Velden Jvd. Ablation of GLRX in KRASG12D induced lung cancer elevates tumorigenesis and is associated with enhanced protein s-glutathionylation Free Radical Biology and Medicine. 128. DOI: 10.1016/J.Freeradbiomed.2018.10.165  0.459
2018 Wetering Cvd, Aboushousha R, Chia SB, Manuel A, Bates J, Velden Jvd, Reynaert N, Vliet Avd, Wouters E, Janssen-Heininger Y. Glutathione-S-transferase π promotes interleukin-1β induced pulmonary inflammation in association with S-glutathionylation of the glycolysis regulator, pyruvate kinase M2 Free Radical Biology and Medicine. 128. DOI: 10.1016/J.Freeradbiomed.2018.10.067  0.552
2018 Manuel A, Qian X, Aboushousha R, Wetering Cvd, Chia SB, Lam Y, Velden Jvd, Vliet Avd, Dixon A, Poynter M, Irvin C, Janssen-Heininger Y. S-glutathionylation of pyruvate kinase M2 is associated with metabolic reprogramming and cytokine production in the development of allergic obese airway disease Free Radical Biology and Medicine. 128. DOI: 10.1016/J.Freeradbiomed.2018.10.035  0.413
2018 Kumar A, Elko E, Janssen-Heininger Y, Anathy V. Ablation of PDIA3 alleviates pulmonary fibrosis in mice Free Radical Biology and Medicine. 128. DOI: 10.1016/J.Freeradbiomed.2018.10.029  0.467
2018 Janssen-Heininger Y, Anathy V, Elko E, Kumar A, Vliet Avd. Control of protein cysteine oxidation in lung fibrosis via a coordinated network of protein disulfide oxidoreductases Free Radical Biology and Medicine. 128. DOI: 10.1016/J.Freeradbiomed.2018.10.025  0.499
2018 Elko E, Anathy V, Velden Jvd, Vliet Avd, Janssen-Heininger Y. Oxidation state of peroxiredoxin 4 in lungs from patients with pulmonary fibrosis and mouse models of fibrosis Free Radical Biology and Medicine. 128. DOI: 10.1016/J.Freeradbiomed.2018.10.014  0.45
2017 Janssen-Heininger Y. Glutathione, Glutaredoxin And S-Glutathionylation In Lung Disease Free Radical Biology and Medicine. 112: 3. DOI: 10.1016/J.Freeradbiomed.2017.10.350  0.459
2017 Elko E, Anathy V, Lahue K, Velden Jvd, Vliet Avd, Janssen-Heininger Y. Role of Peroxiredoxin 4 in Collagen Deposition in Mouse Models of Fibrosis Free Radical Biology and Medicine. 112: 187. DOI: 10.1016/J.Freeradbiomed.2017.10.292  0.477
2017 Velden Jvd, Kinsey M, Chia S, Lahue K, Qian X, Janssen-Heininger Y. GSTP1-catalyzed PKM2 S-Glutathionylation Regulates Glycolysis in Non-small Cell Lung Cancer and is Attenuated with a Clinically Relevant inhibitor of Glutathione-S-transferase P Free Radical Biology and Medicine. 112: 104-105. DOI: 10.1016/J.Freeradbiomed.2017.10.158  0.444
2016 Eurlings IM, Reynaert NL, van de Wetering C, Aesif SW, Mercken EM, de Cabo R, van der Velden JL, Janssen-Heininger YM, Wouters EF, Dentener MA. Involvement of JNK in TNFα Driven Remodelling. American Journal of Respiratory Cell and Molecular Biology. PMID 27875656 DOI: 10.1183/13993003.Congress-2015.Pa5058  0.467
2016 Habibovic A, Hristova M, Heppner DE, Danyal K, Ather JL, Janssen-Heininger YM, Irvin CG, Poynter ME, Lundblad LK, Dixon AE, Geiszt M, van der Vliet A. DUOX1 mediates persistent epithelial EGFR activation, mucous cell metaplasia, and airway remodeling during allergic asthma. Jci Insight. 1: e88811. PMID 27812543 DOI: 10.1172/Jci.Insight.88811  0.352
2016 McMillan DH, van der Velden JL, Lahue KG, Qian X, Schneider RW, Iberg MS, Nolin JD, Abdalla S, Casey DT, Tew KD, Townsend DM, Henderson CJ, Wolf CR, Butnor KJ, Taatjes DJ, ... ... Janssen-Heininger YM, et al. Attenuation of lung fibrosis in mice with a clinically relevant inhibitor of glutathione-S-transferase π. Jci Insight. 1. PMID 27358914 DOI: 10.1172/jci.insight.85717  0.404
2016 Jones JT, Qian X, van der Velden JL, Chia SB, McMillan DH, Flemer S, Hoffman SM, Lahue KG, Schneider RW, Nolin JD, Anathy V, van der Vliet A, Townsend DM, Tew KD, Janssen-Heininger YM. Glutathione S-transferase pi modulates NF-κB activation and pro-inflammatory responses in lung epithelial cells. Redox Biology. 8: 375-382. PMID 27058114 DOI: 10.1016/j.redox.2016.03.005  0.343
2016 Hoffman SM, Qian X, Nolin JD, Chapman DG, Chia SB, Lahue KG, Schneider R, Ather JL, Randall MJ, McMillan DH, Jones JT, Taatjes DJ, Aliyeva M, Daphtary N, Abdalla S, ... ... Janssen-Heininger YM, et al. Ablation of Glutaredoxin-1 Modulates House Dust Mite-induced Allergic Airways Disease in Mice. American Journal of Respiratory Cell and Molecular Biology. PMID 27035878 DOI: 10.1165/Rcmb.2015-0401Oc  0.334
2016 Hoffman SM, Nolin JD, Jones JT, Lahue KG, Chapman DG, Aliyeva M, Daphtary N, Lundblad LK, Abdalla S, Ather JL, Ho YS, Irvin CG, Anathy V, Wouters EF, Poynter ME, ... Janssen-Heininger YM, et al. Ablation of the Thiol Transferase Glutaredoxin-1 Augments Protein S-Glutathionylation and Modulates Type 2 Inflammatory Responses and IL-17 in a House Dust Mite Model of Allergic Airway Disease in Mice. Annals of the American Thoracic Society. 13: S97. PMID 27027965 DOI: 10.1513/Annalsats.201510-656Mg  0.343
2015 Hoffman SM, Chapman DG, Lahue KG, Cahoon JM, Rattu GK, Daphtary N, Aliyeva M, Fortner KA, Erzurum SC, Comhair SA, Woodruff PG, Bhakta N, Dixon AE, Irvin CG, Janssen-Heininger YM, et al. Protein disulfide isomerase-endoplasmic reticulum resident protein 57 regulates allergen-induced airways inflammation, fibrosis, and hyperresponsiveness. The Journal of Allergy and Clinical Immunology. PMID 26435004 DOI: 10.1016/J.Jaci.2015.08.018  0.317
2015 Hoffman S, Nolin J, McMillan D, Wouters E, Janssen-Heininger Y, Reynaert N. Thiol redox chemistry: role of protein cysteine oxidation and altered redox homeostasis in allergic inflammation and asthma. Journal of Cellular Biochemistry. 116: 884-92. PMID 25565397 DOI: 10.1002/Jcb.25017  0.404
2015 Jones JT, McMillan DH, Qian X, Lahue K, Velden Jvd, Tew K, Janssen-Heininger Y. 307 - GSTP Modulates NF-kB Activation and Pro-Inflammatory Responses in Lung Epithelial Cells Free Radical Biology and Medicine. 87. DOI: 10.1016/J.Freeradbiomed.2015.10.357  0.441
2015 McMillan D, Lahue K, Iberg M, Schneider R, Qian X, Velden Jvd, Abdalla S, Flemer S, Tew K, Vliet Avd, Anathy V, Janssen-Heininger Y. 306 - TLK117-Induced GSTP Inhibition Attenuates TGF-P-Induced Lung Fibrotic Remodeling Free Radical Biology and Medicine. 87. DOI: 10.1016/J.Freeradbiomed.2015.10.356  0.426
2015 Anathy V, Hoffman S, Chapman D, Janssen-Heininger Y, Poynter M. 60 - Protein Disulfide Isomerase-ERp57 Regulates Allergic Asthma Phenotype Free Radical Biology and Medicine. 87. DOI: 10.1016/J.Freeradbiomed.2015.10.099  0.328
2014 Chapman DG, Tully JE, Nolin JD, Janssen-Heininger YM, Irvin CG. Animal models of allergic airways disease: where are we and where to next? Journal of Cellular Biochemistry. 115: 2055-64. PMID 25043224 DOI: 10.1002/jcb.24881  0.751
2014 Nolin JD, Tully JE, Hoffman SM, Guala AS, van der Velden JL, Poynter ME, van der Vliet A, Anathy V, Janssen-Heininger YM. The glutaredoxin/S-glutathionylation axis regulates interleukin-17A-induced proinflammatory responses in lung epithelial cells in association with S-glutathionylation of nuclear factor κB family proteins. Free Radical Biology & Medicine. 73: 143-53. PMID 24816292 DOI: 10.1016/j.freeradbiomed.2014.04.028  0.77
2014 Li L, Wei C, Kim IK, Janssen-Heininger Y, Gupta S. Inhibition of nuclear factor-κB in the lungs prevents monocrotaline-induced pulmonary hypertension in mice. Hypertension. 63: 1260-9. PMID 24614212 DOI: 10.1161/HYPERTENSIONAHA.114.03220  0.385
2014 van der Velden JL, Hoffman SM, Alcorn JF, Tully JE, Chapman DG, Lahue KG, Guala AS, Lundblad LK, Aliyeva M, Daphtary N, Irvin CG, Janssen-Heininger YM. Absence of c-Jun NH2-terminal kinase 1 protects against house dust mite-induced pulmonary remodeling but not airway hyperresponsiveness and inflammation. American Journal of Physiology. Lung Cellular and Molecular Physiology. 306: L866-75. PMID 24610935 DOI: 10.1152/ajplung.00153.2013  0.793
2014 Anathy V, Aesif SW, Hoffman SM, Bement JL, Guala AS, Lahue KG, Leclair LW, Suratt BT, Cool CD, Wargo MJ, Janssen-Heininger YMW. Glutaredoxin-1 attenuates s-glutathionylation of the death receptor fas and decreases resolution of pseudomonas aeruginosa pneumonia American Journal of Respiratory and Critical Care Medicine. 189: 463-474. PMID 24325366 DOI: 10.1164/rccm.201310-1905OC  0.339
2014 Hristova M, Habibovic A, Janssen-Heininger Y, Geiszt M, van der Vliet A. DUOX1 Mediates Innate Airway Epithelial Responses to Airborne Allergens via Oxidative Activation of Epidermal Growth Factor Receptor Signaling Free Radical Biology and Medicine. 76: S167. DOI: 10.1016/J.Freeradbiomed.2014.10.057  0.355
2014 McMillan D, Lahue K, Nolin J, Hoffman S, Abdalla S, Chapman D, Velden Jvd, Anathy V, Janssen-Heininger Y. 400 - Attenuation of GSTP1 Decreases Fas SGlutathionylation-Mediated Lung Epithelial Cell Apoptosis and Fibrotic Remodeling Free Radical Biology and Medicine. 76. DOI: 10.1016/J.Freeradbiomed.2014.10.049  0.455
2013 Tully JE, Hoffman SM, Lahue KG, Nolin JD, Anathy V, Lundblad LK, Daphtary N, Aliyeva M, Black KE, Dixon AE, Poynter ME, Irvin CG, Janssen-Heininger YM. Epithelial NF-κB orchestrates house dust mite-induced airway inflammation, hyperresponsiveness, and fibrotic remodeling. Journal of Immunology (Baltimore, Md. : 1950). 191: 5811-21. PMID 24227776 DOI: 10.4049/jimmunol.1301329  0.794
2013 Janssen-Heininger YM, Nolin JD, Hoffman SM, van der Velden JL, Tully JE, Lahue KG, Abdalla ST, Chapman DG, Reynaert NL, van der Vliet A, Anathy V. Emerging mechanisms of glutathione-dependent chemistry in biology and disease. Journal of Cellular Biochemistry. 114: 1962-8. PMID 23554102 DOI: 10.1002/jcb.24551  0.755
2013 Gorissen SH, Hristova M, Habibovic A, Sipsey LM, Spiess PC, Janssen-Heininger YM, van der Vliet A. Dual oxidase-1 is required for airway epithelial cell migration and bronchiolar reepithelialization after injury. American Journal of Respiratory Cell and Molecular Biology. 48: 337-45. PMID 23239498 DOI: 10.1165/rcmb.2012-0393OC  0.327
2012 Hoffman SM, Tully JE, Lahue KG, Anathy V, Nolin JD, Guala AS, van der Velden JL, Ho YS, Aliyeva M, Daphtary N, Lundblad LK, Irvin CG, Janssen-Heininger YM. Genetic ablation of glutaredoxin-1 causes enhanced resolution of airways hyperresponsiveness and mucus metaplasia in mice with allergic airways disease. American Journal of Physiology. Lung Cellular and Molecular Physiology. 303: L528-38. PMID 22752969 DOI: 10.1152/ajplung.00167.2012  0.773
2012 Anathy V, Roberson E, Cunniff B, Nolin JD, Hoffman S, Spiess P, Guala AS, Lahue KG, Goldman D, Flemer S, van der Vliet A, Heintz NH, Budd RC, Tew KD, Janssen-Heininger YM. Oxidative processing of latent Fas in the endoplasmic reticulum controls the strength of apoptosis. Molecular and Cellular Biology. 32: 3464-78. PMID 22751926 DOI: 10.1128/MCB.00125-12  0.743
2012 Tully JE, Nolin JD, Guala AS, Hoffman SM, Roberson EC, Lahue KG, Van Der Velden J, Anathy V, Blackwell TS, Janssen-Heininger YMW. Cooperation between classical and alternative NF-κB pathways regulates proinflammatory responses in epithelial cells American Journal of Respiratory Cell and Molecular Biology. 47: 497-508. PMID 22652196 DOI: 10.1165/Rcmb.2012-0014Oc  0.744
2012 Van der Velden J, Janssen-Heininger YM, Mandalapu S, Scheller EV, Kolls JK, Alcorn JF. Differential requirement for c-Jun N-terminal kinase 1 in lung inflammation and host defense. Plos One. 7: e34638. PMID 22514650 DOI: 10.1371/journal.pone.0034638  0.369
2012 van der Velden JL, Guala AS, Leggett SE, Sluimer J, Badura EC, Janssen-Heininger YM. Induction of a mesenchymal expression program in lung epithelial cells by wingless protein (Wnt)/β-catenin requires the presence of c-Jun N-terminal kinase-1 (JNK1). American Journal of Respiratory Cell and Molecular Biology. 47: 306-14. PMID 22461429 DOI: 10.1165/rcmb.2011-0297OC  0.332
2012 Anathy V, Roberson EC, Guala AS, Godburn KE, Budd RC, Janssen-Heininger YMW. Redox-based regulation of apoptosis: S-glutathionylation as a regulatory mechanism to control cell death Antioxidants and Redox Signaling. 16: 496-505. PMID 21929356 DOI: 10.1089/ars.2011.4281  0.728
2012 Roberson EC, Tully JE, Guala AS, Reiss JN, Godburn KE, Pociask DA, Alcorn JF, Riches DWH, Dienz O, Janssen-Heininger YMW, Anathy V. Influenza induces endoplasmic reticulum stress, caspase-12-dependent apoptosis, and c-Jun N-terminal kinase-mediated transforming growth factor-β release in lung epithelial cells American Journal of Respiratory Cell and Molecular Biology. 46: 573-581. PMID 21799120 DOI: 10.1165/rcmb.2010-0460OC  0.731
2011 Aesif SW, Kuipers I, van der Velden J, Tully JE, Guala AS, Anathy V, Sheely JI, Reynaert NL, Wouters EF, van der Vliet A, Janssen-Heininger YM. Activation of the glutaredoxin-1 gene by nuclear factor κB enhances signaling. Free Radical Biology & Medicine. 51: 1249-57. PMID 21762778 DOI: 10.1016/J.Freeradbiomed.2011.06.025  0.776
2011 Kuipers I, Guala AS, Aesif SW, Konings G, Bouwman FG, Mariman EC, Wouters EF, Janssen-Heininger YM, Reynaert NL. Cigarette smoke targets glutaredoxin 1, increasing s-glutathionylation and epithelial cell death. American Journal of Respiratory Cell and Molecular Biology. 45: 931-7. PMID 21454804 DOI: 10.1165/Rcmb.2010-0249Oc  0.347
2011 Olson N, Kasahara DI, Hristova M, Bernstein R, Janssen-Heininger Y, van der Vliet A. Modulation of NF-κB and hypoxia-inducible factor--1 by S-nitrosoglutathione does not alter allergic airway inflammation in mice. American Journal of Respiratory Cell and Molecular Biology. 44: 813-23. PMID 20693401 DOI: 10.1165/Rcmb.2010-0035Oc  0.529
2011 Ather JL, Hodgkins SR, Janssen-Heininger YM, Poynter ME. Airway epithelial NF-κB activation promotes allergic sensitization to an innocuous inhaled antigen. American Journal of Respiratory Cell and Molecular Biology. 44: 631-8. PMID 20581095 DOI: 10.1165/rcmb.2010-0106OC  0.377
2011 Aesif SW, Anathy V, Kuipers I, Guala AS, Reiss JN, Ho YS, Janssen-Heininger YM. Ablation of glutaredoxin-1 attenuates lipopolysaccharide-induced lung inflammation and alveolar macrophage activation. American Journal of Respiratory Cell and Molecular Biology. 44: 491-9. PMID 20539014 DOI: 10.1165/rcmb.2009-0136OC  0.411
2011 Janssen-Heininger Y, Anathy V. Role of Endoplasmic Reticulum Stress and Oxidative Stress in Influenza Virus Induced Lung Fibrosis Free Radical Biology and Medicine. 51. DOI: 10.1016/J.Freeradbiomed.2011.10.344  0.367
2010 Chu HW, Gally F, Thaikoottathil J, Janssen-Heininger YM, Wu Q, Zhang G, Reisdorph N, Case S, Minor M, Smith S, Jiang D, Michels N, Simon G, Martin RJ. SPLUNC1 regulation in airway epithelial cells: role of Toll-like receptor 2 signaling. Respiratory Research. 11: 155. PMID 21054862 DOI: 10.1186/1465-9921-11-155  0.335
2010 Janssen-Heininger YMW, Aesif SW, Van Der Velden J, Guala AS, Reiss JN, Roberson EC, Budd RC, Reynaert NL, Anathy V. Regulation of apoptosis through cysteine oxidation: Implications for fibrotic lung disease Annals of the New York Academy of Sciences. 1203: 23-28. PMID 20716279 DOI: 10.1111/j.1749-6632.2010.05553.x  0.771
2010 Heintz NH, Janssen-Heininger YM, Mossman BT. Asbestos, lung cancers, and mesotheliomas: from molecular approaches to targeting tumor survival pathways. American Journal of Respiratory Cell and Molecular Biology. 42: 133-9. PMID 20068227 DOI: 10.1165/rcmb.2009-0206TR  0.318
2010 Ather JL, Alcorn JF, Brown AL, Guala AS, Suratt BT, Janssen-Heininger YM, Poynter ME. Distinct functions of airway epithelial nuclear factor-kappaB activity regulate nitrogen dioxide-induced acute lung injury. American Journal of Respiratory Cell and Molecular Biology. 43: 443-51. PMID 19901348 DOI: 10.1165/rcmb.2008-0416OC  0.431
2010 Alcorn JF, Ckless K, Brown AL, Guala AS, Kolls JK, Poynter ME, Irvin CG, van der Vliet A, Janssen-Heininger YM. Strain-dependent activation of NF-kappaB in the airway epithelium and its role in allergic airway inflammation. American Journal of Physiology. Lung Cellular and Molecular Physiology. 298: L57-66. PMID 19897746 DOI: 10.1152/ajplung.00037.2009  0.357
2009 Aesif SW, Anathy V, Havermans M, Guala AS, Ckless K, Taatjes DJ, Janssen-Heininger YM. In situ analysis of protein S-glutathionylation in lung tissue using glutaredoxin-1-catalyzed cysteine derivatization. The American Journal of Pathology. 175: 36-45. PMID 19556513 DOI: 10.2353/ajpath.2009.080736  0.336
2009 Janssen-Heininger YM, Poynter ME, Aesif SW, Pantano C, Ather JL, Reynaert NL, Ckless K, Anathy V, van der Velden J, Irvin CG, van der Vliet A. Nuclear factor kappaB, airway epithelium, and asthma: avenues for redox control. Proceedings of the American Thoracic Society. 6: 249-55. PMID 19387025 DOI: 10.1513/pats.200806-054RM  0.373
2009 Alcorn JF, van der Velden J, Brown AL, McElhinney B, Irvin CG, Janssen-Heininger YM. c-Jun N-terminal kinase 1 is required for the development of pulmonary fibrosis. American Journal of Respiratory Cell and Molecular Biology. 40: 422-32. PMID 18836136 DOI: 10.1165/rcmb.2008-0174OC  0.385
2008 Ckless K, Lampert A, Reiss J, Kasahara D, Poynter ME, Irvin CG, Lundblad LK, Norton R, van der Vliet A, Janssen-Heininger YM. Inhibition of arginase activity enhances inflammation in mice with allergic airway disease, in association with increases in protein S-nitrosylation and tyrosine nitration. Journal of Immunology (Baltimore, Md. : 1950). 181: 4255-64. PMID 18768883  0.434
2008 Pantano C, Ather JL, Alcorn JF, Poynter ME, Brown AL, Guala AS, Beuschel SL, Allen GB, Whittaker LA, Bevelander M, Irvin CG, Janssen-Heininger YM. Nuclear factor-kappaB activation in airway epithelium induces inflammation and hyperresponsiveness. American Journal of Respiratory and Critical Care Medicine. 177: 959-69. PMID 18263801 DOI: 10.1164/rccm.200707-1096OC  0.334
2007 Reynaert NL, Aesif SW, McGovern T, Brown A, Wouters EF, Irvin CG, Janssen-Heininger YM. Catalase overexpression fails to attenuate allergic airways disease in the mouse. Journal of Immunology (Baltimore, Md. : 1950). 178: 3814-21. PMID 17339480 DOI: 10.4049/Jimmunol.178.6.3814  0.352
2007 Haegens A, Barrett TF, Gell J, Shukla A, Macpherson M, Vacek P, Poynter ME, Butnor KJ, Janssen-Heininger YM, Steele C, Mossman BT. Airway epithelial NF-kappaB activation modulates asbestos-induced inflammation and mucin production in vivo. Journal of Immunology (Baltimore, Md. : 1950). 178: 1800-8. PMID 17237430 DOI: 10.4049/Jimmunol.178.3.1800  0.378
2007 Ckless K, van der Vliet A, Janssen-Heininger Y. Oxidative-nitrosative stress and post-translational protein modifications: implications to lung structure-function relations. Arginase modulates NF-kappaB activity via a nitric oxide-dependent mechanism. American Journal of Respiratory Cell and Molecular Biology. 36: 645-53. PMID 17218616 DOI: 10.1165/Rcmb.2006-0329Sm  0.475
2007 Pantano C, Anathy V, Ranjan P, Heintz NH, Janssen-Heininger YM. Nonphagocytic oxidase 1 causes death in lung epithelial cells via a TNF-RI-JNK signaling axis. American Journal of Respiratory Cell and Molecular Biology. 36: 473-9. PMID 17079781 DOI: 10.1165/rcmb.2006-0109OC  0.383
2007 Reynaert NL, Wouters EF, Janssen-Heininger YM. Modulation of glutaredoxin-1 expression in a mouse model of allergic airway disease. American Journal of Respiratory Cell and Molecular Biology. 36: 147-51. PMID 16980552 DOI: 10.1165/Rcmb.2006-0259Rc  0.378
2007 Ochkur S, Biechele T, Jacobsen E, McElhinney B, Protheroe C, Pero R, Borchers M, O'Neill K, Colbert D, McGarry M, Janssen-Heininger Y, Irvin C, Shen H, Lee J, Lee N. Co-Expression of IL-5 and Eotaxin-2 in Mice Creates a Novel and Eosinophil-dependent Pulmonary Model of Respiratory Inflammation Characteristic of Human Disease Journal of Allergy and Clinical Immunology. 119: S151. DOI: 10.1016/J.Jaci.2006.11.529  0.404
2006 Pantano C, Reynaert NL, van der Vliet A, Janssen-Heininger YM. Redox-sensitive kinases of the nuclear factor-kappaB signaling pathway. Antioxidants & Redox Signaling. 8: 1791-806. PMID 16987032 DOI: 10.1089/ars.2006.8.1791  0.325
2006 Reynaert NL, van der Vliet A, Guala AS, McGovern T, Hristova M, Pantano C, Heintz NH, Heim J, Ho YS, Matthews DE, Wouters EF, Janssen-Heininger YM. Dynamic redox control of NF-kappaB through glutaredoxin-regulated S-glutathionylation of inhibitory kappaB kinase beta. Proceedings of the National Academy of Sciences of the United States of America. 103: 13086-91. PMID 16916935 DOI: 10.1073/Pnas.0603290103  0.308
2006 Poynter ME, Persinger RL, Irvin CG, Butnor KJ, van Hirtum H, Blay W, Heintz NH, Robbins J, Hemenway D, Taatjes DJ, Janssen-Heininger Y. Nitrogen dioxide enhances allergic airway inflammation and hyperresponsiveness in the mouse. American Journal of Physiology. Lung Cellular and Molecular Physiology. 290: L144-52. PMID 16085673 DOI: 10.1152/Ajplung.00131.2005  0.409
2005 Reynaert NL, Ckless K, Wouters EF, van der Vliet A, Janssen-Heininger YM. Nitric oxide and redox signaling in allergic airway inflammation. Antioxidants & Redox Signaling. 7: 129-43. PMID 15650402 DOI: 10.1089/Ars.2005.7.129  0.33
2005 Ochkur S, Protheroe C, Bichele T, McElhinney B, Pero R, Borchers M, O'Neill K, Colbert D, McGarry M, Janssen-Heininger Y, Irvin C, Shen H, Lee N, Lee J. Synergistic effects of IL-5 and eotaxin-2 in the mouse lung mimics pathologies observed in asthma patients Journal of Allergy and Clinical Immunology. 115: S118. DOI: 10.1016/J.Jaci.2004.12.484  0.375
2004 Ckless K, Reynaert NL, Taatjes DJ, Lounsbury KM, van der Vliet A, Janssen-Heininger Y. In situ detection and visualization of S-nitrosylated proteins following chemical derivatization: identification of Ran GTPase as a target for S-nitrosylation. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 11: 216-27. PMID 15566968 DOI: 10.1016/J.Niox.2004.06.002  0.356
2004 Poynter ME, Cloots R, van Woerkom T, Butnor KJ, Vacek P, Taatjes DJ, Irvin CG, Janssen-Heininger YM. NF-kappa B activation in airways modulates allergic inflammation but not hyperresponsiveness. Journal of Immunology (Baltimore, Md. : 1950). 173: 7003-9. PMID 15557197  0.366
2004 Shrivastava P, Pantano C, Watkin R, McElhinney B, Guala A, Poynter ML, Persinger RL, Budd R, Janssen-Heininger Y. Reactive nitrogen species-induced cell death requires Fas-dependent activation of c-Jun N-terminal kinase. Molecular and Cellular Biology. 24: 6763-72. PMID 15254243 DOI: 10.1128/Mcb.24.15.6763-6772.2004  0.398
2004 Reynaert NL, Ckless K, Korn SH, Vos N, Guala AS, Wouters EF, van der Vliet A, Janssen-Heininger YM. Nitric oxide represses inhibitory kappaB kinase through S-nitrosylation. Proceedings of the National Academy of Sciences of the United States of America. 101: 8945-50. PMID 15184672 DOI: 10.1073/Pnas.0400588101  0.305
2003 McElhinney B, Poynter ME, Shrivastava P, Hazen SL, Janssen-Heininger YM. Eosinophil peroxidase catalyzes JNK-mediated membrane blebbing in a Rho kinase-dependent manner. Journal of Leukocyte Biology. 74: 897-907. PMID 12960269 DOI: 10.1189/Jlb.0103028  0.306
2003 Pantano C, Shrivastava P, McElhinney B, Janssen-Heininger Y. Hydrogen peroxide signaling through tumor necrosis factor receptor 1 leads to selective activation of c-Jun N-terminal kinase. The Journal of Biological Chemistry. 278: 44091-6. PMID 12939259 DOI: 10.1074/jbc.M308487200  0.341
2003 Poynter ME, Irvin CG, Janssen-Heininger YM. A prominent role for airway epithelial NF-kappa B activation in lipopolysaccharide-induced airway inflammation. Journal of Immunology (Baltimore, Md. : 1950). 170: 6257-65. PMID 12794158  0.392
2002 Janssen-Heininger YM, Persinger RL, Korn SH, Pantano C, McElhinney B, Reynaert NL, Langen RC, Ckless K, Shrivastava P, Poynter ME. Reactive nitrogen species and cell signaling: implications for death or survival of lung epithelium. American Journal of Respiratory and Critical Care Medicine. 166: S9-S16. PMID 12471083 DOI: 10.1164/rccm.2206008  0.337
2002 Persinger RL, Poynter ME, Ckless K, Janssen-Heininger YM. Molecular mechanisms of nitrogen dioxide induced epithelial injury in the lung. Molecular and Cellular Biochemistry. 234: 71-80. PMID 12162462  0.366
2002 Poynter ME, Irvin CG, Janssen-Heininger YM. Rapid activation of nuclear factor-kappaB in airway epithelium in a murine model of allergic airway inflammation. The American Journal of Pathology. 160: 1325-34. PMID 11943717  0.442
2000 Fine A, Janssen-Heininger Y, Soultanakis RP, Swisher SG, Uhal BD. Apoptosis in lung pathophysiology. American Journal of Physiology. Lung Cellular and Molecular Physiology. 279: L423-7. PMID 10956615 DOI: 10.1152/Ajplung.2000.279.3.L423  0.456
1999 Poynter ME, Janssen-Heininger YMW, Buder-Hoffmann S, Taatjes DJ, Mossman BT. Measurement of oxidant-induced signal transduction proteins using cell imaging Free Radical Biology and Medicine. 27: 1164-1172. PMID 10641707 DOI: 10.1016/S0891-5849(99)00202-6  0.307
1999 Janssen-Heininger YM, Macara I, Mossman BT. Cooperativity between oxidants and tumor necrosis factor in the activation of nuclear factor (NF)-kappaB: requirement of Ras/mitogen-activated protein kinases in the activation of NF-kappaB by oxidants. American Journal of Respiratory Cell and Molecular Biology. 20: 942-52. PMID 10226064 DOI: 10.1165/AJRCMB.20.5.3452  0.304
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