Nika N. Danial - Publications

Affiliations: 
Medical Sciences Harvard University, Cambridge, MA, United States 
Area:
Cell Biology

55 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Ngo J, Choi DW, Stanley IA, Stiles L, Molina AJA, Chen PH, Lako A, Sung ICH, Goswami R, Kim MY, Miller N, Baghdasarian S, Kim-Vasquez D, Jones AE, Roach B, ... ... Danial NN, et al. Mitochondrial morphology controls fatty acid utilization by changing CPT1 sensitivity to malonyl-CoA. The Embo Journal. e111901. PMID 36917141 DOI: 10.15252/embj.2022111901  0.746
2022 Prew MS, Adhikary U, Choi DW, Portero EP, Paulo JA, Gowda P, Budhraja A, Opferman JT, Gygi SP, Danial NN, Walensky LD. MCL-1 is a master regulator of cancer dependency on fatty acid oxidation. Cell Reports. 41: 111445. PMID 36198266 DOI: 10.1016/j.celrep.2022.111445  0.329
2022 Wei P, Bott AJ, Cluntun AA, Morgan JT, Cunningham CN, Schell JC, Ouyang Y, Ficarro SB, Marto JA, Danial NN, DeBerardinis RJ, Rutter J. Mitochondrial pyruvate supports lymphoma proliferation by fueling a glutamate pyruvate transaminase 2-dependent glutaminolysis pathway. Science Advances. 8: eabq0117. PMID 36179030 DOI: 10.1126/sciadv.abq0117  0.418
2020 Wang CH, Lundh M, Fu A, Kriszt R, Huang TL, Lynes MD, Leiria LO, Shamsi F, Darcy J, Greenwood BP, Narain NR, Tolstikov V, Smith KL, Emanuelli B, Chang YT, ... ... Danial NN, et al. CRISPR-engineered human brown-like adipocytes prevent diet-induced obesity and ameliorate metabolic syndrome in mice. Science Translational Medicine. 12. PMID 32848096 DOI: 10.1126/Scitranslmed.Aaz8664  0.37
2020 Mejhert N, Kuruvilla L, Gabriel KR, Elliott SD, Guie MA, Wang H, Lai ZW, Lane EA, Christiano R, Danial NN, Farese RV, Walther TC. Partitioning of MLX-Family Transcription Factors to Lipid Droplets Regulates Metabolic Gene Expression. Molecular Cell. PMID 32023484 DOI: 10.1016/J.Molcel.2020.01.014  0.356
2019 Brown FD, Sen DR, LaFleur MW, Godec J, Lukacs-Kornek V, Schildberg FA, Kim HJ, Yates KB, Ricoult SJH, Bi K, Trombley JD, Kapoor VN, Stanley IA, Cremasco V, Danial NN, et al. Fibroblastic reticular cells enhance T cell metabolism and survival via epigenetic remodeling. Nature Immunology. PMID 31636464 DOI: 10.1038/S41590-019-0515-X  0.704
2019 Lane EA, Choi DW, Garcia-Haro L, Levine ZG, Tedoldi M, Walker S, Danial NN. HCF-1 Regulates De Novo Lipogenesis through a Nutrient-Sensitive Complex with ChREBP. Molecular Cell. PMID 31227231 DOI: 10.1016/J.Molcel.2019.05.019  0.312
2018 Fu A, Danial NN. Grasping for aspartate in tumour metabolism. Nature Cell Biology. PMID 29941932 DOI: 10.1038/S41556-018-0137-9  0.353
2016 Norberg E, Lako A, Chen PH, Stanley IA, Zhou F, Ficarro SB, Chapuy B, Chen L, Rodig S, Shin D, Choi DW, Lee S, Shipp MA, Marto JA, Danial NN. Differential contribution of the mitochondrial translation pathway to the survival of diffuse large B-cell lymphoma subsets. Cell Death and Differentiation. PMID 27768122 DOI: 10.1038/Cdd.2016.116  0.748
2016 Samardžić D, Danial N, Scorrano L. In vitro and in vivo study of the role of the mitochondria - shaping protein opa1 in cancer Biochimica Et Biophysica Acta. 1857. DOI: 10.1016/J.Bbabio.2016.04.246  0.384
2016 Danial NN. Metabolic heterogeneity in molecular subtypes of diffuse large B cell lymphoma Biochimica Et Biophysica Acta. 1857. DOI: 10.1016/J.Bbabio.2016.04.033  0.378
2015 Giménez-Cassina A, Danial NN. Regulation of mitochondrial nutrient and energy metabolism by BCL-2 family proteins. Trends in Endocrinology and Metabolism: Tem. 26: 165-75. PMID 25748272 DOI: 10.1016/J.Tem.2015.02.004  0.496
2015 Ljubicic S, Polak K, Fu A, Wiwczar J, Szlyk B, Chang Y, Alvarez-Perez JC, Bird GH, Walensky LD, Garcia-Ocaña A, Danial NN. Phospho-BAD BH3 mimicry protects β cells and restores functional β cell mass in diabetes. Cell Reports. 10: 497-504. PMID 25640178 DOI: 10.1016/J.Celrep.2014.12.056  0.314
2015 Ribeiro SM, Giménez-Cassina A, Danial NN. Measurement of mitochondrial oxygen consumption rates in mouse primary neurons and astrocytes. Methods in Molecular Biology (Clifton, N.J.). 1241: 59-69. PMID 25308488 DOI: 10.1007/978-1-4939-1875-1_6  0.329
2014 Lo JC, Ljubicic S, Leibiger B, Kern M, Leibiger IB, Moede T, Kelly ME, Chatterjee Bhowmick D, Murano I, Cohen P, Banks AS, Khandekar MJ, Dietrich A, Flier JS, Cinti S, ... ... Danial NN, et al. Adipsin is an adipokine that improves β cell function in diabetes. Cell. 158: 41-53. PMID 24995977 DOI: 10.1016/J.Cell.2014.06.005  0.309
2014 Schoumacher M, Hurov KE, Lehár J, Yan-Neale Y, Mishina Y, Sonkin D, Korn JM, Flemming D, Jones MD, Antonakos B, Cooke VG, Steiger J, Ledell J, Stump MD, Sellers WR, ... Danial NN, et al. Inhibiting Tankyrases sensitizes KRAS-mutant cancer cells to MEK inhibitors via FGFR2 feedback signaling. Cancer Research. 74: 3294-305. PMID 24747911 DOI: 10.1158/0008-5472.Can-14-0138-T  0.343
2014 Akbay EA, Moslehi J, Christensen CL, Saha S, Tchaicha JH, Ramkissoon SH, Stewart KM, Carretero J, Kikuchi E, Zhang H, Cohoon TJ, Murray S, Liu W, Uno K, Fisch S, ... ... Danial NN, et al. D-2-hydroxyglutarate produced by mutant IDH2 causes cardiomyopathy and neurodegeneration in mice. Genes & Development. 28: 479-90. PMID 24589777 DOI: 10.1101/Gad.231233.113  0.699
2014 Szlyk B, Braun CR, Ljubicic S, Patton E, Bird GH, Osundiji MA, Matschinsky FM, Walensky LD, Danial NN. A phospho-BAD BH3 helix activates glucokinase by a mechanism distinct from that of allosteric activators. Nature Structural & Molecular Biology. 21: 36-42. PMID 24317490 DOI: 10.1038/Nsmb.2717  0.307
2014 Stanley IA, Ribeiro SM, Giménez-Cassina A, Norberg E, Danial NN. Changing appetites: the adaptive advantages of fuel choice. Trends in Cell Biology. 24: 118-27. PMID 24018218 DOI: 10.1016/J.Tcb.2013.07.010  0.714
2014 Shao W, Schoumacher M, Hurov K, Lehar J, Yan-Neale Y, Mishina Y, Sonkin D, Korn J, Flemming D, Jones M, Antonakos B, Cooke V, Stump M, Danial N, Sellers W. Abstract LB-107: Inhibiting TNKS sensitizes KRAS mutant cancer cells to MEK inhibitors by suppressing FGFR2 feedback signaling Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Lb-107  0.314
2014 Samardzic D, Danial N, Scorrano L. The role of the mitochondria-shaping protein Opa1 in the BCR vs. OxPhos subset of diffuse large B cell lymphoma Biochimica Et Biophysica Acta. 1837. DOI: 10.1016/J.Bbabio.2014.05.309  0.369
2013 Danial NN, Hartman AL, Stafstrom CE, Thio LL. How does the ketogenic diet work? Four potential mechanisms. Journal of Child Neurology. 28: 1027-33. PMID 23670253 DOI: 10.1177/0883073813487598  0.35
2013 Yan J, Xiang J, Lin Y, Ma J, Zhang J, Zhang H, Sun J, Danial NN, Liu J, Lin A. Inactivation of BAD by IKK inhibits TNFα-induced apoptosis independently of NF-κB activation. Cell. 152: 304-15. PMID 23332762 DOI: 10.1016/J.Cell.2012.12.021  0.338
2013 Shah DI, Takahashi-Makise N, Cooney JD, Li L, Schultz IJ, Pierce EL, Narla A, Seguin A, Hattangadi SM, Medlock AE, Langer NB, Dailey TA, Hurst SN, Faccenda D, Wiwczar JM, ... ... Danial NN, et al. Erratum: Corrigendum: Mitochondrial Atpif1 regulates haem synthesis in developing erythroblasts Nature. 496: 386-386. DOI: 10.1038/Nature12078  0.41
2012 Shah DI, Takahashi-Makise N, Cooney JD, Li L, Schultz IJ, Pierce EL, Narla A, Seguin A, Hattangadi SM, Medlock AE, Langer NB, Dailey TA, Hurst SN, Faccenda D, Wiwczar JM, ... ... Danial NN, et al. Mitochondrial Atpif1 regulates haem synthesis in developing erythroblasts. Nature. 491: 608-12. PMID 23135403 DOI: 10.1038/Nature11536  0.422
2012 Caro P, Kishan AU, Norberg E, Stanley IA, Chapuy B, Ficarro SB, Polak K, Tondera D, Gounarides J, Yin H, Zhou F, Green MR, Chen L, Monti S, Marto JA, ... ... Danial NN, et al. Metabolic signatures uncover distinct targets in molecular subsets of diffuse large B cell lymphoma. Cancer Cell. 22: 547-60. PMID 23079663 DOI: 10.1016/J.Ccr.2012.08.014  0.744
2012 Chae YC, Caino MC, Lisanti S, Ghosh JC, Dohi T, Danial NN, Villanueva J, Ferrero S, Vaira V, Santambrogio L, Bosari S, Languino LR, Herlyn M, Altieri DC. Control of tumor bioenergetics and survival stress signaling by mitochondrial HSP90s. Cancer Cell. 22: 331-44. PMID 22975376 DOI: 10.1016/J.Ccr.2012.07.015  0.381
2012 Fu S, Fan J, Blanco J, Gimenez-Cassina A, Danial NN, Watkins SM, Hotamisligil GS. Polysome profiling in liver identifies dynamic regulation of endoplasmic reticulum translatome by obesity and fasting. Plos Genetics. 8: e1002902. PMID 22927828 DOI: 10.1371/Journal.Pgen.1002902  0.337
2012 Giménez-Cassina A, Martínez-François JR, Fisher JK, Szlyk B, Polak K, Wiwczar J, Tanner GR, Lutas A, Yellen G, Danial NN. BAD-dependent regulation of fuel metabolism and K(ATP) channel activity confers resistance to epileptic seizures. Neuron. 74: 719-30. PMID 22632729 DOI: 10.1016/J.Neuron.2012.03.032  0.35
2011 Osundiji MA, Godes ML, Evans ML, Danial NN. BAD modulates counterregulatory responses to hypoglycemia and protective glucoprivic feeding. Plos One. 6: e28016. PMID 22162752 DOI: 10.1371/Journal.Pone.0028016  0.343
2011 Shah DI, Takahashi-Makise N, Cooney JD, Li L, Schultz I, Pierce EL, Narla A, Hattangadi S, Langer N, Chen W, Dailey TA, Hurst SN, Faccenda D, Wiwczar J, Law TC, ... ... Danial N, et al. Mitochondrial Atpif1 Regulates Heme Synthesis in Developing Erythroblasts Blood. 118: 343-343. DOI: 10.1182/Blood.V118.21.343.343  0.446
2010 Gimenez-Cassina A, Danial NN. Noxa: a sweet twist to survival and more. Molecular Cell. 40: 687-8. PMID 21145478 DOI: 10.1016/J.Molcel.2010.11.037  0.359
2010 Danial NN, Gimenez-Cassina A, Tondera D. Homeostatic functions of BCL-2 proteins beyond apoptosis. Advances in Experimental Medicine and Biology. 687: 1-32. PMID 20919635 DOI: 10.1007/978-1-4419-6706-0_1  0.389
2010 Simarro M, Gimenez-Cassina A, Kedersha N, Lazaro JB, Adelmant GO, Marto JA, Rhee K, Tisdale S, Danial N, Benarafa C, Orduña A, Anderson P. Fast kinase domain-containing protein 3 is a mitochondrial protein essential for cellular respiration. Biochemical and Biophysical Research Communications. 401: 440-6. PMID 20869947 DOI: 10.1016/J.Bbrc.2010.09.075  0.452
2010 Shah DI, Takahasi-Makise N, Schultz I, Pierce EL, Li L, Vogin G, Brigham BS, Zhou Y, Brugnara C, Campanella M, Danial N, Ward DM, Kaplan J, Paw BH. atpif1 regulates Mitochondrial Heme Synthesis In Developing Erythroid Cells Blood. 116: 163-163. DOI: 10.1182/Blood.V116.21.163.163  0.425
2009 Roy SS, Madesh M, Davies E, Antonsson B, Danial N, Hajnóczky G. Bad targets the permeability transition pore independent of Bax or Bak to switch between Ca2+-dependent cell survival and death. Molecular Cell. 33: 377-88. PMID 19217411 DOI: 10.1016/J.Molcel.2009.01.018  0.443
2008 Danial NN. BAD: undertaker by night, candyman by day Oncogene. 27. PMID 19641507 DOI: 10.1038/Onc.2009.44  0.434
2008 Hettiarachchi KD, Zimmet PZ, Danial NN, Myers MA. Transplacental exposure to the vacuolar-ATPase inhibitor bafilomycin disrupts survival signaling in β cells and delays neonatal remodeling of the endocrine pancreas Experimental and Toxicologic Pathology. 60: 295-306. PMID 18486461 DOI: 10.1016/J.Etp.2008.02.009  0.348
2008 Danial NN, Walensky LD, Zhang CY, Choi CS, Fisher JK, Molina AJ, Datta SR, Pitter KL, Bird GH, Wikstrom JD, Deeney JT, Robertson K, Morash J, Kulkarni A, Neschen S, et al. Dual role of proapoptotic BAD in insulin secretion and beta cell survival. Nature Medicine. 14: 144-53. PMID 18223655 DOI: 10.1038/Nm1717  0.376
2007 Danial NN. BCL-2 family proteins: critical checkpoints of apoptotic cell death. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 7254-63. PMID 18094405 DOI: 10.1158/1078-0432.Ccr-07-1598  0.351
2007 Wikstrom JD, Katzman SM, Mohamed H, Twig G, Graf SA, Heart E, Molina AJ, Corkey BE, de Vargas LM, Danial NN, Collins S, Shirihai OS. beta-Cell mitochondria exhibit membrane potential heterogeneity that can be altered by stimulatory or toxic fuel levels. Diabetes. 56: 2569-78. PMID 17686943 DOI: 10.2337/Db06-0757  0.417
2007 Brunelle JK, Shroff EH, Perlman H, Strasser A, Moraes CT, Flavell RA, Danial NN, Keith B, Thompson CB, Chandel NS. Loss of Mcl-1 protein and inhibition of electron transport chain together induce anoxic cell death. Molecular and Cellular Biology. 27: 1222-35. PMID 17145774 DOI: 10.1128/Mcb.01535-06  0.414
2006 Frezza C, Cipolat S, Martins de Brito O, Micaroni M, Beznoussenko GV, Rudka T, Bartoli D, Polishuck RS, Danial NN, De Strooper B, Scorrano L. OPA1 controls apoptotic cristae remodeling independently from mitochondrial fusion. Cell. 126: 177-89. PMID 16839885 DOI: 10.1016/J.Cell.2006.06.025  0.4
2005 Schinzel AC, Takeuchi O, Huang Z, Fisher JK, Zhou Z, Rubens J, Hetz C, Danial NN, Moskowitz MA, Korsmeyer SJ. Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia. Proceedings of the National Academy of Sciences of the United States of America. 102: 12005-10. PMID 16103352 DOI: 10.1073/Pnas.0505294102  0.406
2004 Limnander A, Danial NN, Rothman PB. v-Abl signaling disrupts SOCS-1 function in transformed pre-B cells. Molecular Cell. 15: 329-41. PMID 15304214 DOI: 10.1016/J.Molcel.2004.06.041  0.32
2004 Danial NN, Korsmeyer SJ. Cell death: critical control points. Cell. 116: 205-19. PMID 14744432 DOI: 10.1016/S0092-8674(04)00046-7  0.375
2003 Danial NN, Gramm CF, Scorrano L, Zhang CY, Krauss S, Ranger AM, Datta SR, Greenberg ME, Licklider LJ, Lowell BB, Gygi SP, Korsmeyer SJ. BAD and glucokinase reside in a mitochondrial complex that integrates glycolysis and apoptosis. Nature. 424: 952-6. PMID 12931191 DOI: 10.1038/Nature01825  0.451
2003 Ranger AM, Zha J, Harada H, Datta SR, Danial NN, Gilmore AP, Kutok JL, Le Beau MM, Greenberg ME, Korsmeyer SJ. Bad-deficient mice develop diffuse large B cell lymphoma. Proceedings of the National Academy of Sciences of the United States of America. 100: 9324-9. PMID 12876200 DOI: 10.1073/Pnas.1533446100  0.402
2002 Oki S, Limnander A, Danial NN, Rothman PB. Functional involvement of Akt signaling downstream of Jak1 in v-Abl-induced activation of hematopoietic cells. Blood. 100: 966-73. PMID 12130510 DOI: 10.1182/Blood.V100.3.966  0.338
2000 Danial NN, Rothman P. JAK-STAT signaling activated by Abl oncogenes. Oncogene. 19: 2523-31. PMID 10851051 DOI: 10.1038/Sj.Onc.1203484  0.316
1999 Dorsch M, Danial NN, Rothman PB, Goff SP. A thrombopoietin receptor mutant deficient in Jak-STAT activation mediates proliferation but not differentiation in UT-7 cells. Blood. 94: 2676-85. PMID 10515871 DOI: 10.1182/Blood.V94.8.2676.420K28_2676_2685  0.387
1999 Harris MB, Chang CC, Berton MT, Danial NN, Zhang J, Kuehner D, Ye BH, Kvatyuk M, Pandolfi PP, Cattoretti G, Dalla-Favera R, Rothman PB. Transcriptional repression of Stat6-dependent interleukin-4-induced genes by BCL-6: specific regulation of iepsilon transcription and immunoglobulin E switching. Molecular and Cellular Biology. 19: 7264-75. PMID 10490661 DOI: 10.1128/Mcb.19.10.7264  0.342
1998 Danial NN, Losman JA, Lu T, Yip N, Krishnan K, Krolewski J, Goff SP, Wang JY, Rothman PB. Direct interaction of Jak1 and v-Abl is required for v-Abl-induced activation of STATs and proliferation. Molecular and Cellular Biology. 18: 6795-804. PMID 9774693 DOI: 10.1128/Mcb.18.11.6795  0.361
1997 Dorsch M, Fan PD, Danial NN, Rothman PB, Goff SP. The thrombopoietin receptor can mediate proliferation without activation of the Jak-STAT pathway. The Journal of Experimental Medicine. 186: 1947-55. PMID 9396763 DOI: 10.1084/Jem.186.12.1947  0.306
1995 Danial NN, Pernis A, Rothman PB. Jak-STAT signaling induced by the v-abl oncogene Science. 269: 1875-1877. PMID 7569929 DOI: 10.1126/Science.7569929  0.302
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