Kirsten H. Limesand - Publications

Affiliations: 
Cancer Biology University of Arizona, Tucson, AZ 
Area:
Molecular Biology, Dentistry, Oncology

47 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Buss LG, Rheinheimer BA, Limesand KH. Radiation-Induced Changes in Energy Metabolism Result in Mitochondrial Dysfunction in Salivary Glands. Biorxiv : the Preprint Server For Biology. PMID 38077038 DOI: 10.1101/2023.11.27.568879  0.344
2023 Buss LG, De Oliveira Pessoa D, Snider JM, Padi M, Martinez JA, Limesand KH. Metabolomics analysis of pathways underlying radiation-induced salivary gland dysfunction stages. Plos One. 18: e0294355. PMID 37983277 DOI: 10.1371/journal.pone.0294355  0.329
2023 Rheinheimer BA, Pasquale MC, Limesand KH, Hoffman MP, Chibly AM. Evaluating the transcriptional landscape and cell-cell communication networks in chronically irradiated parotid glands. Iscience. 26: 106660. PMID 37168562 DOI: 10.1016/j.isci.2023.106660  0.304
2021 Gilman KE, Camden JM, Woods LT, Weisman GA, Limesand KH. Indomethacin Treatment Post-irradiation Improves Mouse Parotid Salivary Gland Function via Modulation of Prostaglandin E Signaling. Frontiers in Bioengineering and Biotechnology. 9: 697671. PMID 34381764 DOI: 10.3389/fbioe.2021.697671  0.465
2021 Meeks LG, De Oliveira Pessoa D, Martinez JA, Limesand KH, Padi M. Integration of metabolomics and transcriptomics reveals convergent pathways driving radiation-induced salivary gland dysfunction. Physiological Genomics. PMID 33522389 DOI: 10.1152/physiolgenomics.00127.2020  0.38
2020 Jasmer KJ, Gilman KE, Muñoz Forti K, Weisman GA, Limesand KH. Radiation-Induced Salivary Gland Dysfunction: Mechanisms, Therapeutics and Future Directions. Journal of Clinical Medicine. 9. PMID 33353023 DOI: 10.3390/jcm9124095  0.401
2020 Wong WY, Gilman K, Limesand KH. Yap activation in irradiated parotid salivary glands is regulated by ROCK activity. Plos One. 15: e0232921. PMID 33151927 DOI: 10.1371/journal.pone.0232921  0.445
2020 Winslow JWW, Limesand KH, Zhao N. The Functions of ZIP8, ZIP14, and ZnT10 in the Regulation of Systemic Manganese Homeostasis. International Journal of Molecular Sciences. 21. PMID 32392784 DOI: 10.3390/Ijms21093304  0.332
2020 Khalafalla MG, Woods LT, Jasmer KJ, Forti KM, Camden JM, Jensen JL, Limesand KH, Galtung HK, Weisman GA. P2 Receptors as Therapeutic Targets in the Salivary Gland: From Physiology to Dysfunction. Frontiers in Pharmacology. 11: 222. PMID 32231563 DOI: 10.3389/Fphar.2020.00222  0.384
2019 Jensen SB, Vissink A, Limesand KH, Reyland ME. Salivary Gland Hypofunction and Xerostomia in Head and Neck Radiation Patients. Journal of the National Cancer Institute. Monographs. 2019. PMID 31425600 DOI: 10.1093/Jncimonographs/Lgz016  0.486
2019 Wong WY, Allie S, Limesand KH. PKCζ and JNK signaling regulate radiation-induced compensatory proliferation in parotid salivary glands. Plos One. 14: e0219572. PMID 31287841 DOI: 10.1371/Journal.Pone.0219572  0.559
2019 Meyer R, Wong WY, Guzman R, Burd R, Limesand K. Radiation Treatment of Organotypic Cultures from Submandibular and Parotid Salivary Glands Models Key In Vivo Characteristics. Journal of Visualized Experiments : Jove. PMID 31157788 DOI: 10.3791/59484  0.455
2019 Gilman KE, Camden JM, Klein RR, Zhang Q, Weisman GA, Limesand KH. P2X7 receptor deletion suppresses γ-radiation-induced hyposalivation. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. PMID 30892913 DOI: 10.1152/Ajpregu.00192.2018  0.492
2018 Lin HH, Limesand KH, Ann DK. Current State of Knowledge on Salivary Gland Cancers. Critical Reviews in Oncogenesis. 23: 139-151. PMID 30311570 DOI: 10.1615/Critrevoncog.2018027598  0.503
2018 Lin HH, Chung Y, Cheng CT, Ouyang C, Fu Y, Kuo CY, Chi KK, Sadeghi M, Chu P, Kung HJ, Li CF, Limesand KH, Ann DK. Autophagic Reliance Promotes Metabolic Reprogramming in Oncogenic KRAS-driven Tumorigenesis. Autophagy. PMID 29956571 DOI: 10.1080/15548627.2018.1450708  0.384
2018 Wong WY, Pier M, Limesand KH. Persistent disruption of lateral junctional complexes and actin cytoskeleton in parotid salivary glands following radiation treatment. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. PMID 29897817 DOI: 10.1152/Ajpregu.00388.2017  0.518
2018 Chibly AM, Wong WY, Pier M, Cheng H, Mu Y, Chen J, Ghosh S, Limesand KH. aPKCζ-dependent Repression of Yap is Necessary for Functional Restoration of Irradiated Salivary Glands with IGF-1. Scientific Reports. 8: 6347. PMID 29679075 DOI: 10.1038/S41598-018-24678-4  0.567
2018 Nguyen VT, Dawson P, Zhang Q, Harris Z, Limesand KH. Administration of growth factors promotes salisphere formation from irradiated parotid salivary glands. Plos One. 13: e0193942. PMID 29590144 DOI: 10.1371/Journal.Pone.0193942  0.528
2017 Khalafalla MG, Woods LT, Camden JM, Khan AA, Limesand KH, Petris MJ, Erb L, Weisman GA. P2X7 receptor antagonism prevents IL-1β release from salivary epithelial cells and reduces inflammation in a mouse model of autoimmune exocrinopathy. The Journal of Biological Chemistry. PMID 28798231 DOI: 10.1074/Jbc.M117.790741  0.325
2017 Meyer S, Chibly AM, Burd R, Limesand KH. Insulin-Like Growth Factor-1-Mediated DNA Repair in Irradiated Salivary Glands Is Sirtuin-1 Dependent. Journal of Dental Research. 96: 225-232. PMID 28106504 DOI: 10.1177/0022034516677529  0.472
2016 Harris Z, Donovan MG, Branco GM, Limesand KH, Burd R. Quercetin as an Emerging Anti-Melanoma Agent: A Four-Focus Area Therapeutic Development Strategy. Frontiers in Nutrition. 3: 48. PMID 27843913 DOI: 10.3389/Fnut.2016.00048  0.345
2015 Morgan-Bathke M, Lin HH, Ann DK, Limesand KH. The Role of Autophagy in Salivary Gland Homeostasis and Stress Responses. Journal of Dental Research. PMID 26092378 DOI: 10.1177/0022034515590796  0.704
2015 Goldberg EL, Romero-Aleshire MJ, Renkema KR, Ventevogel MS, Chew WM, Uhrlaub JL, Smithey MJ, Limesand KH, Sempowski GD, Brooks HL, Nikolich-Žugich J. Lifespan-extending caloric restriction or mTOR inhibition impair adaptive immunity of old mice by distinct mechanisms. Aging Cell. 14: 130-8. PMID 25424641 DOI: 10.1111/Acel.12280  0.324
2014 Chibly AM, Nguyen T, Limesand KH. Palliative Care for Salivary Gland Dysfunction Highlights the Need for Regenerative Therapies: A Review on Radiation and Salivary Gland Stem Cells. Journal of Palliative Care & Medicine. 4. PMID 26693098 DOI: 10.4172/2165-7386.1000180  0.506
2014 Morgan-Bathke M, Harris ZI, Arnett DG, Klein RR, Burd R, Ann DK, Limesand KH. The Rapalogue, CCI-779, improves salivary gland function following radiation. Plos One. 9: e113183. PMID 25437438 DOI: 10.1371/Journal.Pone.0113183  0.749
2014 Hill G, Headon D, Harris ZI, Huttner K, Limesand KH. Pharmacological activation of the EDA/EDAR signaling pathway restores salivary gland function following radiation-induced damage. Plos One. 9: e112840. PMID 25409170 DOI: 10.1371/Journal.Pone.0112840  0.517
2014 Chibly AM, Querin L, Harris Z, Limesand KH. Label-retaining cells in the adult murine salivary glands possess characteristics of adult progenitor cells. Plos One. 9: e107893. PMID 25238060 DOI: 10.1371/Journal.Pone.0107893  0.488
2014 Morgan-Bathke M, Hill GA, Harris ZI, Lin HH, Chibly AM, Klein RR, Burd R, Ann DK, Limesand KH. Autophagy correlates with maintenance of salivary gland function following radiation. Scientific Reports. 4: 5206. PMID 24903000 DOI: 10.1038/Srep05206  0.755
2014 Kusne Y, Goldberg EL, Parker SS, Hapak SM, Maskaykina IY, Chew WM, Limesand KH, Brooks HL, Price TJ, Sanai N, Nikolich-Zugich J, Ghosh S. Contrasting effects of chronic, systemic treatment with mTOR inhibitors rapamycin and metformin on adult neural progenitors in mice. Age (Dordrecht, Netherlands). 36: 199-212. PMID 23949159 DOI: 10.1007/S11357-013-9572-5  0.306
2013 Morgan-Bathke M, Lin HH, Chibly AM, Zhang W, Sun X, Chen CH, Flodby P, Borok Z, Wu R, Arnett D, Klein RR, Ann DK, Limesand KH. Deletion of ATG5 shows a role of autophagy in salivary homeostatic control. Journal of Dental Research. 92: 911-7. PMID 23884556 DOI: 10.1177/0022034513499350  0.719
2013 Limesand KH, Chibly AM, Fribley A. Impact of targeting insulin-like growth factor signaling in head and neck cancers. Growth Hormone & Igf Research : Official Journal of the Growth Hormone Research Society and the International Igf Research Society. 23: 135-40. PMID 23816396 DOI: 10.1016/J.Ghir.2013.06.001  0.38
2012 Martin KL, Hill GA, Klein RR, Arnett DG, Burd R, Limesand KH. Prevention of radiation-induced salivary gland dysfunction utilizing a CDK inhibitor in a mouse model. Plos One. 7: e51363. PMID 23236487 DOI: 10.1371/Journal.Pone.0051363  0.521
2012 Mendoza EE, Pocceschi MG, Kong X, Leeper DB, Caro J, Limesand KH, Burd R. Control of Glycolytic Flux by AMP-Activated Protein Kinase in Tumor Cells Adapted to Low pH. Translational Oncology. 5: 208-16. PMID 22741040 DOI: 10.1593/Tlo.11319  0.336
2011 Vargas AJ, Sittadjody S, Thangasamy T, Mendoza EE, Limesand KH, Burd R. Exploiting tyrosinase expression and activity in melanocytic tumors: quercetin and the central role of p53. Integrative Cancer Therapies. 10: 328-40. PMID 21196432 DOI: 10.1177/1534735410391661  0.344
2011 Victory K, Burd R, Fribley A, Sittadjody S, Arnett D, Klein RR, Limesand KH. Head and neck tumor cell radiation response occurs in the presence of IGF1. Journal of Dental Research. 90: 347-52. PMID 21076120 DOI: 10.1177/0022034510388037  0.529
2010 Mitchell GC, Fillinger JL, Sittadjody S, Avila JL, Burd R, Limesand KH. IGF1 activates cell cycle arrest following irradiation by reducing binding of ΔNp63 to the p21 promoter. Cell Death & Disease. 1: e50. PMID 21480565 DOI: 10.1038/Cddis.2010.28  0.63
2010 Vissink A, Mitchell JB, Baum BJ, Limesand KH, Jensen SB, Fox PC, Elting LS, Langendijk JA, Coppes RP, Reyland ME. Clinical management of salivary gland hypofunction and xerostomia in head-and-neck cancer patients: successes and barriers. International Journal of Radiation Oncology, Biology, Physics. 78: 983-91. PMID 20970030 DOI: 10.1016/J.Ijrobp.2010.06.052  0.481
2010 Grundmann O, Fillinger JL, Victory KR, Burd R, Limesand KH. Restoration of radiation therapy-induced salivary gland dysfunction in mice by post therapy IGF-1 administration. Bmc Cancer. 10: 417. PMID 20698985 DOI: 10.1186/1471-2407-10-417  0.534
2010 Limesand KH, Avila JL, Victory K, Chang HH, Shin YJ, Grundmann O, Klein RR. Insulin-like growth factor-1 preserves salivary gland function after fractionated radiation. International Journal of Radiation Oncology, Biology, Physics. 78: 579-86. PMID 20638195 DOI: 10.1016/J.Ijrobp.2010.03.035  0.509
2010 Thangasamy T, Sittadjody S, Mitchell GC, Mendoza EE, Radhakrishnan VM, Limesand KH, Burd R. Quercetin abrogates chemoresistance in melanoma cells by modulating deltaNp73. Bmc Cancer. 10: 282. PMID 20540768 DOI: 10.1186/1471-2407-10-282  0.58
2009 Grundmann O, Mitchell GC, Limesand KH. Sensitivity of salivary glands to radiation: from animal models to therapies. Journal of Dental Research. 88: 894-903. PMID 19783796 DOI: 10.1177/0022034509343143  0.684
2009 Limesand KH, Said S, Anderson SM. Suppression of radiation-induced salivary gland dysfunction by IGF-1. Plos One. 4: e4663. PMID 19252741 DOI: 10.1371/journal.pone.0004663  0.456
2009 Avila JL, Grundmann O, Burd R, Limesand KH. Radiation-induced salivary gland dysfunction results from p53-dependent apoptosis. International Journal of Radiation Oncology, Biology, Physics. 73: 523-9. PMID 19147016 DOI: 10.1016/J.Ijrobp.2008.09.036  0.534
2008 Thangasamy T, Sittadjody S, Limesand KH, Burd R. Tyrosinase overexpression promotes ATM-dependent p53 phosphorylation by quercetin and sensitizes melanoma cells to dacarbazine. Cellular Oncology : the Official Journal of the International Society For Cellular Oncology. 30: 371-87. PMID 18791269 DOI: 10.3233/Clo-2008-0441  0.361
2007 Thangasamy T, Sittadjody S, Lanza-Jacoby S, Wachsberger PR, Limesand KH, Burd R. Quercetin selectively inhibits bioreduction and enhances apoptosis in melanoma cells that overexpress tyrosinase. Nutrition and Cancer. 59: 258-68. PMID 18001220 DOI: 10.1080/01635580701499545  0.323
2006 Limesand KH, Schwertfeger KL, Anderson SM. MDM2 is required for suppression of apoptosis by activated Akt1 in salivary acinar cells. Molecular and Cellular Biology. 26: 8840-56. PMID 16982679 DOI: 10.1128/Mcb.01846-05  0.389
2006 Humphries MJ, Limesand KH, Schneider JC, Nakayama KI, Anderson SM, Reyland ME. Suppression of apoptosis in the protein kinase Cdelta null mouse in vivo. The Journal of Biological Chemistry. 281: 9728-37. PMID 16452485 DOI: 10.1074/Jbc.M507851200  0.311
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