| Year |
Citation |
Score |
| 2019 |
Day M, Maclay T, Cyr A, Hasham MG, Chow K, Keniston E, Mills K. Targeting Homologous Recombination in Lymphoid Malignancies: Evaluation of Four Small Molecule Inhibitors of RAD51 Blood. 134: 2080-2080. DOI: 10.1182/Blood-2019-131747 |
0.405 |
|
| 2019 |
Aprahamian T, Keniston E, Branca J, Hasham MG, Day M, Mills K. CYT-0853, a Novel RAD51 Inhibitor, Modulates Immunoregulatory B-Lymphocytes Blood. 134: 2330-2330. DOI: 10.1182/blood-2019-131311 |
0.312 |
|
| 2019 |
Kumar S, Gkotzamanidou M, Talluri S, Day M, Neptune M, Potluri LB, Chakraborty C, Mills K, Shammas MA, Munshi NC. Ongoing Spontaneous DNA Damage Creates Synthetic Lethality Targeted By Novel RAD51 Inhibitors in Multiple Myeloma Blood. 134: 4378-4378. DOI: 10.1182/blood-2019-129121 |
0.337 |
|
| 2018 |
Wilson JJ, Chow KH, Labrie NJ, Branca JA, Sproule TJ, Perkins BRA, Wolf EE, Costa M, Stafford G, Rosales C, Mills KD, Roopenian DC, Hasham MG. Enhancing the efficacy of glycolytic blockade in cancer cells via RAD51 inhibition. Cancer Biology & Therapy. 1-14. PMID 30183475 DOI: 10.1080/15384047.2018.1507666 |
0.366 |
|
| 2018 |
Hasham MG, Patrick D, Bedard L, Vacca J, McComas C, Castro A, Day M, Mills K. A Novel RAD51 Inhibitor, CYT01B, Shows Anti-Cancer Activity in Preclinical Models of Aid Expressing Lymphomas Blood. 132: 2944-2944. DOI: 10.1182/blood-2018-99-119351 |
0.329 |
|
| 2018 |
Hasham M, Chow K, Maclay T, Cyr A, Patrick D, Day M, Mills KD. Abstract 347: Targeting the AICDA/RAD51 axis: A novel gain-of-function synthetic lethal therapy for the treatment of AICDA-expressing cancers Cancer Research. 78: 347-347. DOI: 10.1158/1538-7445.Am2018-347 |
0.485 |
|
| 2017 |
Ratiu JJ, Racine JJ, Hasham MG, Wang Q, Branca JA, Chapman HD, Zhu J, Donghia N, Philip V, Schott WH, Wasserfall C, Atkinson MA, Mills KD, Leeth CM, Serreze DV. Genetic and Small Molecule Disruption of the AID/RAD51 Axis Similarly Protects Nonobese Diabetic Mice from Type 1 Diabetes through Expansion of Regulatory B Lymphocytes. Journal of Immunology (Baltimore, Md. : 1950). PMID 28461573 DOI: 10.4049/Jimmunol.1700024 |
0.411 |
|
| 2017 |
Mills KD, Roche MI, Cyr A, Maclay T, Hasham MG, Lamont K, Branca J, Cavallo F, Jasin M, Stern A, Kwon Y, Zhao W, Sung P. Abstract 2481: RAD51 and AICDA define a new synthetic lethal interaction that is targetable in multiple tumor types Cancer Research. 77: 2481-2481. DOI: 10.1158/1538-7445.Am2017-2481 |
0.509 |
|
| 2016 |
Godek KM, Venere M, Wu Q, Mills KD, Hickey WF, Rich JN, Compton DA. Chromosomal instability affects the tumorigenicity of glioblastoma tumor-initiating cells. Cancer Discovery. PMID 27001151 DOI: 10.1158/2159-8290.Cd-15-1154 |
0.444 |
|
| 2016 |
Mills K, Hasham M, Lamont K, Philip V, Branca J. RAD51 Modulators Induce Mitotic Catastrophe in Aid Expressing Cells through Multiple Pathways Blood. 128: 4721-4721. DOI: 10.1182/blood.v128.22.4721.4721 |
0.427 |
|
| 2013 |
Mills KD. Tumor suppression: putting p53 in context. Cell Cycle (Georgetown, Tex.). 12: 3461-2. PMID 24131920 DOI: 10.4161/Cc.26806 |
0.481 |
|
| 2013 |
Vuong BQ, Herrick-Reynolds K, Vaidyanathan B, Pucella JN, Ucher AJ, Donghia NM, Gu X, Nicolas L, Nowak U, Rahman N, Strout MP, Mills KD, Stavnezer J, Chaudhuri J. A DNA break- and phosphorylation-dependent positive feedback loop promotes immunoglobulin class-switch recombination. Nature Immunology. 14: 1183-9. PMID 24097111 DOI: 10.1038/Ni.2732 |
0.356 |
|
| 2013 |
Lamont KR, Hasham MG, Donghia NM, Branca J, Chavaree M, Chase B, Breggia A, Hedlund J, Emery I, Cavallo F, Jasin M, Rüter J, Mills KD. Attenuating homologous recombination stimulates an AID-induced antileukemic effect. The Journal of Experimental Medicine. 210: 1021-33. PMID 23589568 DOI: 10.1084/Jem.20121258 |
0.479 |
|
| 2012 |
Hasham MG, Snow KJ, Donghia NM, Branca JA, Lessard MD, Stavnezer J, Shopland LS, Mills KD. Activation-induced cytidine deaminase-initiated off-target DNA breaks are detected and resolved during S phase. Journal of Immunology (Baltimore, Md. : 1950). 189: 2374-82. PMID 22826323 DOI: 10.4049/Jimmunol.1200414 |
0.739 |
|
| 2011 |
Snow KJ, Wright SM, Woo Y, Titus LC, Mills KD, Shopland LS. Nuclear positioning, higher-order folding, and gene expression of Mmu15 sequences are refractory to chromosomal translocation. Chromosoma. 120: 61-71. PMID 20703494 DOI: 10.1007/S00412-010-0290-9 |
0.681 |
|
| 2010 |
Maas SA, Donghia NM, Tompkins K, Foreman O, Mills KD. ARTEMIS stabilizes the genome and modulates proliferative responses in multipotent mesenchymal cells. Bmc Biology. 8: 132. PMID 20979627 DOI: 10.1186/1741-7007-8-132 |
0.541 |
|
| 2010 |
Hasham MG, Donghia NM, Coffey E, Maynard J, Snow KJ, Ames J, Wilpan RY, He Y, King BL, Mills KD. Widespread genomic breaks generated by activation-induced cytidine deaminase are prevented by homologous recombination. Nature Immunology. 11: 820-6. PMID 20657597 DOI: 10.1038/Ni.1909 |
0.752 |
|
| 2009 |
Singh P, Alley TL, Wright SM, Kamdar S, Schott W, Wilpan RY, Mills KD, Graber JH. Global changes in processing of mRNA 3' untranslated regions characterize clinically distinct cancer subtypes. Cancer Research. 69: 9422-30. PMID 19934316 DOI: 10.1158/0008-5472.Can-09-2236 |
0.373 |
|
| 2009 |
Ng SH, Maas SA, Petkov PM, Mills KD, Paigen K. Colocalization of somatic and meiotic double strand breaks near the Myc oncogene on mouse chromosome 15. Genes, Chromosomes & Cancer. 48: 925-30. PMID 19603522 DOI: 10.1002/Gcc.20693 |
0.59 |
|
| 2009 |
Wright SM, Woo YH, Alley TL, Shirley BJ, Akeson EC, Snow KJ, Maas SA, Elwell RL, Foreman O, Mills KD. Complex oncogenic translocations with gene amplification are initiated by specific DNA breaks in lymphocytes. Cancer Research. 69: 4454-60. PMID 19435904 DOI: 10.1158/0008-5472.Can-08-4515 |
0.698 |
|
| 2008 |
Oberdoerffer P, Michan S, McVay M, Mostoslavsky R, Vann J, Park SK, Hartlerode A, Stegmuller J, Hafner A, Loerch P, Wright SM, Mills KD, Bonni A, Yankner BA, Scully R, et al. SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging. Cell. 135: 907-18. PMID 19041753 DOI: 10.1016/J.Cell.2008.10.025 |
0.475 |
|
| 2008 |
Caddle LB, Hasham MG, Schott WH, Shirley BJ, Mills KD. Homologous recombination is necessary for normal lymphocyte development. Molecular and Cellular Biology. 28: 2295-303. PMID 18212067 DOI: 10.1128/Mcb.02139-07 |
0.471 |
|
| 2007 |
Brianna Caddle L, Grant JL, Szatkiewicz J, van Hase J, Shirley BJ, Bewersdorf J, Cremer C, Arneodo A, Khalil A, Mills KD. Chromosome neighborhood composition determines translocation outcomes after exposure to high-dose radiation in primary cells. Chromosome Research : An International Journal On the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology. 15: 1061-73. PMID 18060570 DOI: 10.1007/S10577-007-1181-7 |
0.467 |
|
| 2007 |
Khalil A, Grant JL, Caddle LB, Atzema E, Mills KD, Arneodo A. Chromosome territories have a highly nonspherical morphology and nonrandom positioning. Chromosome Research : An International Journal On the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology. 15: 899-916. PMID 17926137 DOI: 10.1007/S10577-007-1172-8 |
0.353 |
|
| 2007 |
Woo Y, Wright SM, Maas SA, Alley TL, Caddle LB, Kamdar S, Affourtit J, Foreman O, Akeson EC, Shaffer D, Bronson RT, Morse HC, Roopenian D, Mills KD. The nonhomologous end joining factor Artemis suppresses multi-tissue tumor formation and prevents loss of heterozygosity. Oncogene. 26: 6010-20. PMID 17384673 DOI: 10.1038/Sj.Onc.1210430 |
0.691 |
|
| 2006 |
Yan CT, Kaushal D, Murphy M, Zhang Y, Datta A, Chen C, Monroe B, Mostoslavsky G, Coakley K, Gao Y, Mills KD, Fazeli AP, Tepsuporn S, Hall G, Mulligan R, et al. XRCC4 suppresses medulloblastomas with recurrent translocations in p53-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. 103: 7378-83. PMID 16670198 DOI: 10.1073/Pnas.0601938103 |
0.508 |
|
| 2006 |
Morales JC, Franco S, Murphy MM, Bassing CH, Mills KD, Adams MM, Walsh NC, Manis JP, Rassidakis GZ, Alt FW, Carpenter PB. 53BP1 and p53 synergize to suppress genomic instability and lymphomagenesis. Proceedings of the National Academy of Sciences of the United States of America. 103: 3310-5. PMID 16492765 DOI: 10.1073/Pnas.0511259103 |
0.426 |
|
| 2006 |
Mostoslavsky R, Chua KF, Lombard DB, Pang WW, Fischer MR, Gellon L, Liu P, Mostoslavsky G, Franco S, Murphy MM, Mills KD, Patel P, Hsu JT, Hong AL, Ford E, et al. Genomic instability and aging-like phenotype in the absence of mammalian SIRT6. Cell. 124: 315-29. PMID 16439206 DOI: 10.1016/J.Cell.2005.11.044 |
0.444 |
|
| 2004 |
Couëdel C, Mills KD, Barchi M, Shen L, Olshen A, Johnson RD, Nussenzweig A, Essers J, Kanaar R, Li GC, Alt FW, Jasin M. Collaboration of homologous recombination and nonhomologous end-joining factors for the survival and integrity of mice and cells. Genes & Development. 18: 1293-304. PMID 15175261 DOI: 10.1101/Gad.1209204 |
0.426 |
|
| 2004 |
Mills KD, Ferguson DO, Essers J, Eckersdorff M, Kanaar R, Alt FW. Rad54 and DNA Ligase IV cooperate to maintain mammalian chromatid stability. Genes & Development. 18: 1283-92. PMID 15175260 DOI: 10.1101/Gad.1204304 |
0.494 |
|
| 2003 |
Mills KD, Ferguson DO, Alt FW. The role of DNA breaks in genomic instability and tumorigenesis. Immunological Reviews. 194: 77-95. PMID 12846809 DOI: 10.1034/J.1600-065X.2003.00060.X |
0.58 |
|
| 2002 |
Zhu C, Mills KD, Ferguson DO, Lee C, Manis J, Fleming J, Gao Y, Morton CC, Alt FW. Unrepaired DNA breaks in p53-deficient cells lead to oncogenic gene amplification subsequent to translocations. Cell. 109: 811-21. PMID 12110179 DOI: 10.1016/S0092-8674(02)00770-5 |
0.59 |
|
| 1999 |
Mills KD, Sinclair DA, Guarente L. MEC1-dependent redistribution of the Sir3 silencing protein from telomeres to DNA double-strand breaks. Cell. 97: 609-20. PMID 10367890 DOI: 10.1016/S0092-8674(00)80772-2 |
0.454 |
|
| 1998 |
Sinclair D, Mills K, Guarente L. Aging in Saccharomyces cerevisiae Annual Review of Microbiology. 52: 533-560. PMID 9891807 DOI: 10.1146/Annurev.Micro.52.1.533 |
0.365 |
|
| 1998 |
Sinclair DA, Mills K, Guarente L. Molecular mechanisms of yeast aging Trends in Biochemical Sciences. 23: 131-134. PMID 9584615 DOI: 10.1016/S0968-0004(98)01188-8 |
0.305 |
|
| 1997 |
Sinclair DA, Mills K, Guarente L. Accelerated aging and nucleolar fragmentation in yeast SGS1 mutants Science. 277: 1313-1316. PMID 9271578 DOI: 10.1126/Science.277.5330.1313 |
0.354 |
|
| 1997 |
Kennedy BK, Gotta M, Sinclair DA, Mills K, McNabb DS, Murthy M, Pak SM, Laroche T, Gasser SM, Guarente L. Redistribution of silencing proteins from telomeres to the nucleolus is associated with extension of life span in S. cerevisiae. Cell. 89: 381-91. PMID 9150138 DOI: 10.1016/S0092-8674(00)80219-6 |
0.333 |
|
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