| Year |
Citation |
Score |
| 2023 |
Kumar A, Delgoffe GM. Redox and detox: Malate shuttle metabolism keeps exhausted T cells fit. Cell Metabolism. 35: 2101-2103. PMID 38056428 DOI: 10.1016/j.cmet.2023.11.005 |
0.591 |
|
| 2023 |
Lontos K, Wang Y, Joshi SK, Frisch AT, Watson MJ, Kumar A, Menk AV, Wang Y, Cumberland R, Lohmueller J, Carrizosa E, Boyerinas B, Delgoffe GM. Metabolic reprogramming via an engineered PGC-1α improves human chimeric antigen receptor T-cell therapy against solid tumors. Journal For Immunotherapy of Cancer. 11. PMID 36914208 DOI: 10.1136/jitc-2022-006522 |
0.56 |
|
| 2023 |
Ding J, Guyette S, Schrand B, Geirut J, Horton H, Guo G, Delgoffe G, Menk A, Baeuerle PA, Hofmeister R, Tighe R. Mesothelin-targeting T cells bearing a novel T cell receptor fusion construct (TRuC) exhibit potent antitumor efficacy against solid tumors. Oncoimmunology. 12: 2182058. PMID 36875551 DOI: 10.1080/2162402X.2023.2182058 |
0.634 |
|
| 2023 |
Vendetti FP, Pandya P, Clump DA, Schamus-Haynes S, Tavakoli M, diMayorca M, Islam NM, Chang J, Delgoffe GM, Beumer JH, Bakkenist CJ. The schedule of ATR inhibitor AZD6738 can potentiate or abolish antitumor immune responses to radiotherapy. Jci Insight. 8. PMID 36810257 DOI: 10.1172/jci.insight.165615 |
0.532 |
|
| 2022 |
Vignali PDA, DePeaux K, Watson MJ, Ye C, Ford BR, Lontos K, McGaa NK, Scharping NE, Menk AV, Robson SC, Poholek AC, Rivadeneira DB, Delgoffe GM. Hypoxia drives CD39-dependent suppressor function in exhausted T cells to limit antitumor immunity. Nature Immunology. PMID 36543958 DOI: 10.1038/s41590-022-01379-9 |
0.581 |
|
| 2022 |
Lontos K, Wang Y, Colbert M, Kumar A, Joshi S, Philbin M, Wang Y, Frisch A, Lohmueller J, Rivadeneira DB, Delgoffe GM. Fully murine CD105-targeted CAR-T cells provide an immunocompetent model for CAR-T cell biology. Oncoimmunology. 11: 2131229. PMID 36275862 DOI: 10.1080/2162402X.2022.2131229 |
0.574 |
|
| 2022 |
Sugitani N, Vendetti FP, Cipriano AJ, Pandya P, Deppas JJ, Moiseeva TN, Schamus-Haynes S, Wang Y, Palmer D, Osmanbeyoglu HU, Bostwick A, Snyder NW, Gong YN, Aird KM, Delgoffe GM, et al. Thymidine rescues ATR kinase inhibitor-induced deoxyuridine contamination in genomic DNA, cell death, and interferon-α/β expression. Cell Reports. 40: 111371. PMID 36130512 DOI: 10.1016/j.celrep.2022.111371 |
0.374 |
|
| 2022 |
Ford BR, Vignali PDA, Rittenhouse NL, Scharping NE, Peralta R, Lontos K, Frisch AT, Delgoffe GM, Poholek AC. Tumor microenvironmental signals reshape chromatin landscapes to limit the functional potential of exhausted T cells. Science Immunology. 7: eabj9123. PMID 35930654 DOI: 10.1126/sciimmunol.abj9123 |
0.522 |
|
| 2021 |
Banerjee H, Nieves-Rosado H, Kulkarni A, Murter B, McGrath KV, Chandran UR, Chang A, Szymczak-Workman AL, Vujanovic L, Delgoffe GM, Ferris RL, Kane LP. Expression of Tim-3 drives phenotypic and functional changes in Treg cells in secondary lymphoid organs and the tumor microenvironment. Cell Reports. 36: 109699. PMID 34525351 DOI: 10.1016/j.celrep.2021.109699 |
0.538 |
|
| 2021 |
Zhao S, Peralta RM, Avina-Ochoa N, Delgoffe GM, Kaech SM. Metabolic regulation of T cells in the tumor microenvironment by nutrient availability and diet. Seminars in Immunology. 101485. PMID 34462190 DOI: 10.1016/j.smim.2021.101485 |
0.573 |
|
| 2021 |
Delgoffe GM, Xu C, Mackall CL, Green MR, Gottschalk S, Speiser DE, Zehn D, Beavis PA. The role of exhaustion in CAR T cell therapy. Cancer Cell. 39: 885-888. PMID 34256903 DOI: 10.1016/j.ccell.2021.06.012 |
0.496 |
|
| 2021 |
DePeaux K, Delgoffe GM. Metabolic barriers to cancer immunotherapy. Nature Reviews. Immunology. PMID 33927375 DOI: 10.1038/s41577-021-00541-y |
0.422 |
|
| 2021 |
Watson MJ, Vignali PDA, Mullett SJ, Overacre-Delgoffe AE, Peralta RM, Grebinoski S, Menk AV, Rittenhouse NL, DePeaux K, Whetstone RD, Vignali DAA, Hand TW, Poholek AC, Morrison BM, Rothstein JD, ... ... Delgoffe GM, et al. Metabolic support of tumour-infiltrating regulatory T cells by lactic acid. Nature. PMID 33589820 DOI: 10.1038/s41586-020-03045-2 |
0.649 |
|
| 2021 |
Zappasodi R, Serganova I, Cohen IJ, Maeda M, Shindo M, Senbabaoglu Y, Watson MJ, Leftin A, Maniyar R, Verma S, Lubin M, Ko M, Mane MM, Zhong H, Liu C, ... ... Delgoffe GM, et al. CTLA-4 blockade drives loss of T stability in glycolysis-low tumours. Nature. PMID 33588426 DOI: 10.1038/s41586-021-03326-4 |
0.536 |
|
| 2021 |
Scharping NE, Rivadeneira DB, Menk AV, Vignali PDA, Ford BR, Rittenhouse NL, Peralta R, Wang Y, Wang Y, DePeaux K, Poholek AC, Delgoffe GM. Mitochondrial stress induced by continuous stimulation under hypoxia rapidly drives T cell exhaustion. Nature Immunology. PMID 33398183 DOI: 10.1038/s41590-020-00834-9 |
0.628 |
|
| 2020 |
Augustin RC, Delgoffe GM, Najjar YG. Characteristics of the Tumor Microenvironment That Influence Immune Cell Functions: Hypoxia, Oxidative Stress, Metabolic Alterations. Cancers. 12. PMID 33348579 DOI: 10.3390/cancers12123802 |
0.335 |
|
| 2020 |
Cole AJ, Iyengar M, Panesso-Gómez S, O'Hayer PJ, Chan DK, Delgoffe GM, Aird KM, Yoon E, Bai S, Buckanovich RJ. NFATC4 promotes quiescence and chemotherapy resistance in ovarian cancer. Jci Insight. PMID 32182216 DOI: 10.1172/Jci.Insight.131486 |
0.339 |
|
| 2020 |
Yang M, Du W, Yi L, Wu S, He C, Zhai W, Yue C, Sun R, Menk AV, Delgoffe GM, Jiang J, Lu B. Checkpoint molecules coordinately restrain hyperactivated effector T cells in the tumor microenvironment. Oncoimmunology. 9: 1708064. PMID 32076578 DOI: 10.1080/2162402X.2019.1708064 |
0.474 |
|
| 2020 |
Weisel FJ, Mullett SJ, Elsner RA, Menk AV, Trivedi N, Luo W, Wikenheiser D, Hawse WF, Chikina M, Smita S, Conter LJ, Joachim SM, Wendell SG, Jurczak MJ, Winkler TH, ... Delgoffe GM, et al. Germinal center B cells selectively oxidize fatty acids for energy while conducting minimal glycolysis. Nature Immunology. PMID 32066950 DOI: 10.1038/S41590-020-0598-4 |
0.387 |
|
| 2020 |
Zandberg DP, Velez MA, Menk AV, Liu A, Skinner HD, Duvvuri U, Ohr J, Chiosea SI, Nilsen ML, Clump DA, Ferris RL, Delgoffe G. The impact of tumor hypoxia on the clinical efficacy of anti-PD-1 mAb treatment in recurrent/metastatic HNSCC patients (R/M). Journal of Clinical Oncology. 38: 6546-6546. DOI: 10.1200/Jco.2020.38.15_Suppl.6546 |
0.355 |
|
| 2020 |
Delgoffe GM. Abstract IA12: Metabolic barriers to effective immunotherapy of cancer Clinical Cancer Research. 26. DOI: 10.1158/1557-3265.Aacrahns19-Ia12 |
0.481 |
|
| 2020 |
Zappasodi R, Serganova I, Cohen I, Maeda M, Shindo M, Senbabaoglu Y, Leftin A, Maniyar R, Verma S, Lubin M, Ko MK, Mane MM, Ghosh A, Ackerstaff E, Koutcher JA, ... ... Delgoffe GM, et al. Abstract 3257: CTLA-4 blockade drives loss of regulatory T cell functional stability in glycolysis defective tumors Immunology. 80: 3257-3257. DOI: 10.1158/1538-7445.Am2020-3257 |
0.624 |
|
| 2019 |
Teijeira A, Garasa S, Etxeberria I, Gato-Cañas M, Melero I, Delgoffe GM. Metabolic Consequences of T-cell Costimulation in Anticancer Immunity. Cancer Immunology Research. 7: 1564-1569. PMID 31575551 DOI: 10.1158/2326-6066.Cir-19-0115 |
0.68 |
|
| 2019 |
Rivadeneira DB, DePeaux K, Wang Y, Kulkarni A, Tabib T, Menk AV, Sampath P, Lafyatis R, Ferris RL, Sarkar SN, Thorne SH, Delgoffe GM. Oncolytic Viruses Engineered to Enforce Leptin Expression Reprogram Tumor-Infiltrating T Cell Metabolism and Promote Tumor Clearance. Immunity. PMID 31471106 DOI: 10.1016/J.Immuni.2019.07.003 |
0.47 |
|
| 2019 |
Liu C, Chikina M, Deshpande R, Menk AV, Wang T, Tabib T, Brunazzi EA, Vignali KM, Sun M, Stolz DB, Lafyatis RA, Chen W, Delgoffe GM, Workman CJ, Wendell SG, et al. Treg Cells Promote the SREBP1-Dependent Metabolic Fitness of Tumor-Promoting Macrophages via Repression of CD8 T Cell-Derived Interferon-γ. Immunity. PMID 31350177 DOI: 10.1016/J.Immuni.2019.06.017 |
0.593 |
|
| 2019 |
Watson AR, Dai H, Zheng Y, Nakano R, Giannou AD, Menk AV, Stolz DB, Delgoffe GM, Thomson AW. mTORC2 Deficiency Alters the Metabolic Profile of Conventional Dendritic Cells. Frontiers in Immunology. 10: 1451. PMID 31338091 DOI: 10.3389/Fimmu.2019.01451 |
0.448 |
|
| 2019 |
Shao L, Hou W, Scharping NE, Vendetti FP, Srivastava R, Roy CN, Menk AV, Wang Y, Chauvin JM, Karukonda P, Thorne SH, Hornung V, Zarour HM, Bakkenist CJ, Delgoffe GM, et al. IRF1 inhibits antitumor immunity through the upregulation of PD-L1 in the tumor cell. Cancer Immunology Research. PMID 31239318 DOI: 10.1158/2326-6066.Cir-18-0711 |
0.472 |
|
| 2019 |
Piccirillo AR, Hyzny EJ, Beppu LY, Menk AV, Wallace CT, Hawse WF, Buechel HM, Wong BH, Foo JC, Cazenave-Gassiot A, Wenk MR, Delgoffe GM, Watkins SC, Silver DL, D'Cruz LM. The Lysophosphatidylcholine Transporter MFSD2A Is Essential for CD8 Memory T Cell Maintenance and Secondary Response to Infection. Journal of Immunology (Baltimore, Md. : 1950). PMID 31127034 DOI: 10.4049/Jimmunol.1801585 |
0.651 |
|
| 2019 |
Santos PM, Menk AV, Shi J, Tsung A, Delgoffe GM, Butterfield LH. Tumor-derived α-fetoprotein suppresses fatty acid metabolism and oxidative phosphorylation in dendritic cells. Cancer Immunology Research. PMID 30988028 DOI: 10.1158/2326-6066.Cir-18-0513 |
0.379 |
|
| 2019 |
Majumder S, Amatya N, Revu S, Jawale CV, Wu D, Rittenhouse N, Menk A, Kupul S, Du F, Raphael I, Bhattacharjee A, Siebenlist U, Hand TW, Delgoffe GM, Poholek AC, et al. IL-17 metabolically reprograms activated fibroblastic reticular cells for proliferation and survival. Nature Immunology. PMID 30962593 DOI: 10.1038/S41590-019-0367-4 |
0.575 |
|
| 2019 |
Previte DM, Martins CP, O'Connor EC, Marre ML, Coudriet GM, Beck NW, Menk AV, Wright RH, Tse HM, Delgoffe GM, Piganelli JD. Lymphocyte Activation Gene-3 Maintains Mitochondrial and Metabolic Quiescence in Naive CD4 T Cells. Cell Reports. 27: 129-141.e4. PMID 30943396 DOI: 10.1016/J.Celrep.2019.03.004 |
0.665 |
|
| 2019 |
Najjar YG, Menk AV, Sander C, Rao U, Karunamurthy A, Bhatia R, Zhai S, Kirkwood JM, Delgoffe GM. Tumor cell oxidative metabolism as a barrier to PD-1 blockade immunotherapy in melanoma. Jci Insight. PMID 30721155 DOI: 10.1172/Jci.Insight.124989 |
0.519 |
|
| 2019 |
Delgoffe GM. Abstract SY13-03: Reprogramming tumor microenvironment metabolism to improve immunotherapy Cancer Research. 79. DOI: 10.1158/1538-7445.Am2019-Sy13-03 |
0.488 |
|
| 2018 |
Tilstra JS, Avery L, Menk AV, Gordon RA, Smita S, Kane LP, Chikina M, Delgoffe GM, Shlomchik MJ. Kidney-infiltrating T cells in murine lupus nephritis are metabolically and functionally exhausted. The Journal of Clinical Investigation. PMID 30130253 DOI: 10.1172/Jci120859 |
0.677 |
|
| 2018 |
Vendetti FP, Karukonda P, Clump DA, Teo T, Lalonde R, Nugent K, Ballew M, Kiesel BF, Beumer JH, Sarkar SN, Conrads TP, O'Connor MJ, Ferris RL, Tran PT, Delgoffe GM, et al. ATR kinase inhibitor AZD6738 potentiates CD8+ T cell-dependent antitumor activity following radiation. The Journal of Clinical Investigation. PMID 29952768 DOI: 10.1172/Jci96519 |
0.468 |
|
| 2018 |
Revu S, Wu J, Henkel M, Rittenhouse N, Menk A, Delgoffe GM, Poholek AC, McGeachy MJ. IL-23 and IL-1β Drive Human Th17 Cell Differentiation and Metabolic Reprogramming in Absence of CD28 Costimulation. Cell Reports. 22: 2642-2653. PMID 29514093 DOI: 10.1016/J.Celrep.2018.02.044 |
0.495 |
|
| 2018 |
Menk AV, Scharping NE, Rivadeneira DB, Calderon MJ, Watson MJ, Dunstane D, Watkins SC, Delgoffe GM. 4-1BB costimulation induces T cell mitochondrial function and biogenesis enabling cancer immunotherapeutic responses. The Journal of Experimental Medicine. PMID 29511066 DOI: 10.1084/Jem.20171068 |
0.592 |
|
| 2018 |
Menk AV, Scharping NE, Moreci RS, Zeng X, Guy C, Salvatore S, Bae H, Xie J, Young HA, Wendell SG, Delgoffe GM. Early TCR Signaling Induces Rapid Aerobic Glycolysis Enabling Distinct Acute T Cell Effector Functions. Cell Reports. 22: 1509-1521. PMID 29425506 DOI: 10.1016/J.Celrep.2018.01.040 |
0.685 |
|
| 2018 |
Rivadeneira DB, Delgoffe GM. Antitumor T cell reconditioning: improving metabolic fitness for optimal cancer immunotherapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 29386217 DOI: 10.1158/1078-0432.Ccr-17-0894 |
0.602 |
|
| 2018 |
Scharping NE, Menk AV, Delgoffe GM. Abstract 632: The metabolic requirements for effective immunotherapy Immunology. 78: 632-632. DOI: 10.1158/1538-7445.Am2018-632 |
0.495 |
|
| 2018 |
Watson A, Dai H, Diaz-Perez JA, Menk AV, Killeen ME, Delgoffe GM, Mathers AR, Thomson AW. Glycolytic Bias in mTORC2 Deficient Dendritic Cells Potentiates Antigen-Specific Immunity and Accelerates Graft Rejection Transplantation. 102: S48. DOI: 10.1097/01.Tp.0000542610.86701.68 |
0.36 |
|
| 2017 |
Overacre-Delgoffe AE, Chikina M, Dadey RE, Yano H, Brunazzi EA, Shayan G, Horne W, Moskovitz JM, Kolls JK, Sander C, Shuai Y, Normolle DP, Kirkwood JM, Ferris RL, Delgoffe GM, et al. Interferon-γ Drives Treg Fragility to Promote Anti-tumor Immunity. Cell. PMID 28552348 DOI: 10.1016/J.Cell.2017.05.005 |
0.434 |
|
| 2017 |
Downs-Canner S, Berkey S, Delgoffe GM, Edwards RP, Curiel T, Odunsi K, Bartlett DL, Obermajer N. Suppressive IL-17A(+)Foxp3(+) and ex-Th17 IL-17A(neg)Foxp3(+) Treg cells are a source of tumour-associated Treg cells. Nature Communications. 8: 14649. PMID 28290453 DOI: 10.1038/Ncomms14649 |
0.469 |
|
| 2016 |
Phong B, Avery L, Menk AV, Delgoffe GM, Kane LP. Cutting Edge: Murine Mast Cells Rapidly Modulate Metabolic Pathways Essential for Distinct Effector Functions. Journal of Immunology (Baltimore, Md. : 1950). PMID 27974455 DOI: 10.4049/Jimmunol.1601150 |
0.533 |
|
| 2016 |
Scharping NE, Menk AV, Whetstone RD, Zeng X, Delgoffe GM. Efficacy of PD-1 blockade is potentiated by metformin-induced reduction of tumor hypoxia. Cancer Immunology Research. PMID 27941003 DOI: 10.1158/2326-6066.Cir-16-0103 |
0.348 |
|
| 2016 |
Scharping NE, Delgoffe GM. Tumor Microenvironment Metabolism: A New Checkpoint for Anti-Tumor Immunity. Vaccines. 4. PMID 27929420 DOI: 10.3390/Vaccines4040046 |
0.607 |
|
| 2016 |
Delgoffe GM. Filling the Tank: Keeping Antitumor T Cells Metabolically Fit for the Long Haul. Cancer Immunology Research. 4: 1001-1006. PMID 27908931 DOI: 10.1158/2326-6066.Cir-16-0244 |
0.69 |
|
| 2016 |
Delgoffe GM. VHL Brings Warburg into the Memory Spotlight. Immunity. 45: 953-955. PMID 27851921 DOI: 10.1016/J.Immuni.2016.11.001 |
0.516 |
|
| 2016 |
Scharping NE, Menk AV, Moreci RS, Whetstone RD, Dadey RE, Watkins SC, Ferris RL, Delgoffe GM. The Tumor Microenvironment Represses T Cell Mitochondrial Biogenesis to Drive Intratumoral T Cell Metabolic Insufficiency and Dysfunction. Immunity. 45: 701-703. PMID 27653602 DOI: 10.1016/j.immuni.2016.08.009 |
0.565 |
|
| 2016 |
Scharping NE, Menk AV, Moreci RS, Whetstone RD, Dadey RE, Watkins SC, Ferris RL, Delgoffe GM. The Tumor Microenvironment Represses T Cell Mitochondrial Biogenesis to Drive Intratumoral T Cell Metabolic Insufficiency and Dysfunction. Immunity. PMID 27496732 DOI: 10.1016/J.Immuni.2016.07.009 |
0.641 |
|
| 2016 |
Bengsch B, Johnson AL, Kurachi M, Odorizzi PM, Pauken KE, Attanasio J, Stelekati E, McLane LM, Paley MA, Delgoffe GM, Wherry EJ. Bioenergetic Insufficiencies Due to Metabolic Alterations Regulated by the Inhibitory Receptor PD-1 Are an Early Driver of CD8(+) T Cell Exhaustion. Immunity. PMID 27496729 DOI: 10.1016/J.Immuni.2016.07.008 |
0.631 |
|
| 2016 |
Delgoffe GM. Tumor and T-cell metabolism: new insights into melanoma therapy. Clinical Advances in Hematology & Oncology : H&O. 14: 232-4. PMID 27166604 |
0.449 |
|
| 2016 |
Delgoffe GM. PP2A's restraint of mTOR is critical for Treg cell activity. Nature Immunology. 17: 478-9. PMID 27092798 DOI: 10.1038/Ni.3442 |
0.601 |
|
| 2016 |
Pollizzi KN, Sun IH, Patel CH, Lo YC, Oh MH, Waickman AT, Tam AJ, Blosser RL, Wen J, Delgoffe GM, Powell JD. Asymmetric inheritance of mTORC1 kinase activity during division dictates CD8(+) T cell differentiation. Nature Immunology. PMID 27064374 DOI: 10.1038/Ni.3438 |
0.761 |
|
| 2016 |
Turnis ME, Sawant DV, Szymczak-Workman AL, Andrews LP, Delgoffe GM, Yano H, Beres AJ, Vogel P, Workman CJ, Vignali DA. Interleukin-35 Limits Anti-Tumor Immunity. Immunity. 44: 316-29. PMID 26872697 DOI: 10.1016/J.Immuni.2016.01.013 |
0.541 |
|
| 2016 |
Delgoffe GM. Abstract IA08: Identifying and overcoming metabolic checkpoints to antitumor immunity Cancer Immunology Research. 4. DOI: 10.1158/2326-6066.Imm2016-Ia08 |
0.529 |
|
| 2015 |
Delgoffe GM, Powell JD. Feeding an army: The metabolism of T cells in activation, anergy, and exhaustion. Molecular Immunology. PMID 26256793 DOI: 10.1016/J.Molimm.2015.07.026 |
0.772 |
|
| 2015 |
Pollizzi KN, Patel CH, Sun IH, Oh MH, Waickman AT, Wen J, Delgoffe GM, Powell JD. mTORC1 and mTORC2 selectively regulate CD8⁺ T cell differentiation. The Journal of Clinical Investigation. 125: 2090-108. PMID 25893604 DOI: 10.1172/Jci77746 |
0.787 |
|
| 2015 |
Delgoffe GM, Powell JD. Sugar, fat, and protein: new insights into what T cells crave. Current Opinion in Immunology. 33: 49-54. PMID 25665466 DOI: 10.1016/J.Coi.2015.01.015 |
0.756 |
|
| 2015 |
Gupta T, Scharping NE, Moreci RS, Delgoffe GM. Metabolic insufficiency underlies intratumoral cytotoxic T cell dysfunction Journal For Immunotherapy of Cancer. 3: P399. DOI: 10.1186/2051-1426-3-S2-P399 |
0.691 |
|
| 2015 |
Overacre AE, Chikina M, Delgoffe GM, Vignali DA. Elucidating the role of Neuropilin-1 in intra-tumoral regulatory T cell stability Journal For Immunotherapy of Cancer. 3. DOI: 10.1186/2051-1426-3-S2-P274 |
0.42 |
|
| 2015 |
Delgoffe GM, Powell JD. Feeding an army: The metabolism of T cells in activation, anergy, and exhaustion Molecular Immunology. DOI: 10.1016/j.molimm.2015.07.026 |
0.711 |
|
| 2014 |
Delgoffe GM, Vignali DA. A Fox of a different color: FoxA1 programs a new regulatory T cell subset. Nature Medicine. 20: 236-7. PMID 24603791 DOI: 10.1038/Nm.3493 |
0.513 |
|
| 2013 |
Delgoffe GM, Woo SR, Turnis ME, Gravano DM, Guy C, Overacre AE, Bettini ML, Vogel P, Finkelstein D, Bonnevier J, Workman CJ, Vignali DA. Stability and function of regulatory T cells is maintained by a neuropilin-1-semaphorin-4a axis. Nature. 501: 252-6. PMID 23913274 DOI: 10.1038/Nature12428 |
0.547 |
|
| 2012 |
Delgoffe GM, Bettini ML, Vignali DA. Identity crisis: it's not just Foxp3 anymore. Immunity. 37: 759-61. PMID 23159220 DOI: 10.1016/J.Immuni.2012.10.012 |
0.566 |
|
| 2012 |
Collison LW, Delgoffe GM, Guy CS, Vignali KM, Chaturvedi V, Fairweather D, Satoskar AR, Garcia KC, Hunter CA, Drake CG, Murray PJ, Vignali DA. The composition and signaling of the IL-35 receptor are unconventional. Nature Immunology. 13: 290-9. PMID 22306691 DOI: 10.1038/Ni.2227 |
0.373 |
|
| 2012 |
Delgoffe GM, Powell JD. Exploring functional in vivo consequences of the selective genetic ablation of mTOR signaling in T helper lymphocytes Methods in Molecular Biology. 821: 317-327. PMID 22125075 DOI: 10.1007/978-1-61779-430-8_20 |
0.774 |
|
| 2012 |
Szymczak-Workman AL, Delgoffe GM, Green DR, Vignali DAA. Response to Comment on “Cutting Edge: Regulatory T Cells Do Not Mediate Suppression via Programmed Cell Death Pathways” The Journal of Immunology. 188: 5204-5205. DOI: 10.4049/Jimmunol.1290024 |
0.658 |
|
| 2011 |
Szymczak-Workman AL, Delgoffe GM, Green DR, Vignali DA. Cutting edge: regulatory T cells do not mediate suppression via programmed cell death pathways. Journal of Immunology (Baltimore, Md. : 1950). 187: 4416-20. PMID 21949016 DOI: 10.4049/Jimmunol.1100548 |
0.609 |
|
| 2011 |
Delgoffe GM, Murray PJ, Vignali DA. Interpreting mixed signals: the cell's cytokine conundrum. Current Opinion in Immunology. 23: 632-8. PMID 21852079 DOI: 10.1016/J.Coi.2011.07.013 |
0.381 |
|
| 2011 |
Delgoffe GM, Pollizzi KN, Waickman AT, Heikamp E, Meyers DJ, Horton MR, Xiao B, Worley PF, Powell JD. The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2. Nature Immunology. 12: 295-303. PMID 21358638 DOI: 10.1038/Ni.2005 |
0.791 |
|
| 2010 |
Powell JD, Delgoffe GM. The mammalian target of rapamycin: linking T cell differentiation, function, and metabolism. Immunity. 33: 301-11. PMID 20870173 DOI: 10.1016/J.Immuni.2010.09.002 |
0.799 |
|
| 2010 |
Gulen MF, Kang Z, Bulek K, Youzhong W, Kim TW, Chen Y, Altuntas CZ, Sass Bak-Jensen K, McGeachy MJ, Do JS, Xiao H, Delgoffe GM, Min B, Powell JD, Tuohy VK, et al. The receptor SIGIRR suppresses Th17 cell proliferation via inhibition of the interleukin-1 receptor pathway and mTOR kinase activation. Immunity. 32: 54-66. PMID 20060329 DOI: 10.1016/J.Immuni.2009.12.003 |
0.657 |
|
| 2010 |
Gulen MF, Kang Z, Bulek K, Youzhong W, Kim TW, Chen Y, Altuntas CZ, Bak-Jensen KS, McGeachy MJ, Do J, Xiao H, Delgoffe GM, Min B, Powell JD, Tuohy VK, et al. SS1-2 SIGIRR protein suppresses Th17 cell proliferation via negative regulation of the Interleukin-1 receptor pathway and inhibition of mTOR kinase activation Cytokine. 52: 11. DOI: 10.1016/J.Cyto.2010.07.049 |
0.588 |
|
| 2009 |
Zheng Y, Delgoffe GM, Meyer CF, Chan W, Powell JD. Anergic T cells are metabolically anergic. Journal of Immunology (Baltimore, Md. : 1950). 183: 6095-101. PMID 19841171 DOI: 10.4049/Jimmunol.0803510 |
0.788 |
|
| 2009 |
Delgoffe GM, Powell JD. mTOR: taking cues from the immune microenvironment. Immunology. 127: 459-65. PMID 19604300 DOI: 10.1111/J.1365-2567.2009.03125.X |
0.74 |
|
| 2009 |
Delgoffe GM, Kole TP, Cotter RJ, Powell JD. Enhanced interaction between Hsp90 and raptor regulates mTOR signaling upon T cell activation. Molecular Immunology. 46: 2694-8. PMID 19586661 DOI: 10.1182/Blood.V112.11.674.674 |
0.735 |
|
| 2009 |
Delgoffe GM, Kole TP, Zheng Y, Zarek PE, Matthews KL, Xiao B, Worley PF, Kozma SC, Powell JD. The mTOR kinase differentially regulates effector and regulatory T cell lineage commitment. Immunity. 30: 832-44. PMID 19538929 DOI: 10.1016/J.Immuni.2009.04.014 |
0.812 |
|
| 2008 |
Delgoffe GM, Kole TP, Zheng Y, Xiao B, Worley PF, Kozma SC, Powell J. TOR Complex 1 and TOR Complex 2 Differentially Regulate Effector and Regulatory T Cell Differentiation Blood. 112: 675-675. DOI: 10.1182/Blood.V112.11.675.675 |
0.796 |
|
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