Scott Lesley - Publications

Affiliations: 
1990- University of California, Berkeley, Berkeley, CA, United States 

29 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Grunewald J, Klock HE, Cellitti SE, Bursulaya B, McMullan D, Jones DH, Chiu HP, Wang X, Patterson P, Zhou H, Vance J, Nigoghossian E, Tong H, Daniel D, Mallet W, ... ... Lesley SA, et al. Efficient preparation of site-specific antibody-drug conjugates using phosphopantetheinyl transferases. Bioconjugate Chemistry. PMID 26588668 DOI: 10.1021/Acs.Bioconjchem.5B00558  0.716
2014 Elsliger M, Deacon A, Godzik A, Lesley S, Hodgson K, Wooley J, Wüthrich K, Wilson I. JCSG – Adapting Structural Genomics to Eukaryotic Complexes Acta Crystallographica Section a Foundations and Advances. 70: C1148-C1148. DOI: 10.1107/S2053273314088512  0.375
2013 Das D, Hervé M, Elsliger MA, Kadam RU, Grant JC, Chiu HJ, Knuth MW, Klock HE, Miller MD, Godzik A, Lesley SA, Deacon AM, Mengin-Lecreulx D, Wilson IA. Structure and function of a novel LD-carboxypeptidase a involved in peptidoglycan recycling. Journal of Bacteriology. 195: 5555-66. PMID 24123814 DOI: 10.1128/Jb.00900-13  0.311
2012 Shumilin IA, Cymborowski M, Chertihin O, Jha KN, Herr JC, Lesley SA, Joachimiak A, Minor W. Identification of unknown protein function using metabolite cocktail screening. Structure (London, England : 1993). 20: 1715-25. PMID 22940582 DOI: 10.1016/J.Str.2012.07.016  0.332
2011 Ou W, Uno T, Chiu HP, Grünewald J, Cellitti SE, Crossgrove T, Hao X, Fan Q, Quinn LL, Patterson P, Okach L, Jones DH, Lesley SA, Brock A, Geierstanger BH. Site-specific protein modifications through pyrroline-carboxy-lysine residues. Proceedings of the National Academy of Sciences of the United States of America. 108: 10437-42. PMID 21670250 DOI: 10.1073/Pnas.1105197108  0.736
2011 Cellitti SE, Ou W, Chiu HP, Grünewald J, Jones DH, Hao X, Fan Q, Quinn LL, Ng K, Anfora AT, Lesley SA, Uno T, Brock A, Geierstanger BH. D-Ornithine coopts pyrrolysine biosynthesis to make and insert pyrroline-carboxy-lysine. Nature Chemical Biology. 7: 528-30. PMID 21525873 DOI: 10.1038/Nchembio.586  0.7
2011 Das D, Hervé M, Feuerhelm J, Farr CL, Chiu HJ, Elsliger MA, Knuth MW, Klock HE, Miller MD, Godzik A, Lesley SA, Deacon AM, Mengin-Lecreulx D, Wilson IA. Structure and function of the first full-length murein peptide ligase (Mpl) cell wall recycling protein. Plos One. 6: e17624. PMID 21445265 DOI: 10.1371/Journal.Pone.0017624  0.325
2010 Kumar A, Lomize A, Jin KK, Carlton D, Miller MD, Jaroszewski L, Abdubek P, Astakhova T, Axelrod HL, Chiu HJ, Clayton T, Das D, Deller MC, Duan L, Feuerhelm J, ... ... Lesley SA, et al. Open and closed conformations of two SpoIIAA-like proteins (YP_749275.1 and YP_001095227.1) provide insights into membrane association and ligand binding. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 1245-53. PMID 20944218 DOI: 10.1107/S1744309109042481  0.309
2010 Bakolitsa C, Bateman A, Jin KK, McMullan D, Krishna SS, Miller MD, Abdubek P, Acosta C, Astakhova T, Axelrod HL, Burra P, Carlton D, Chiu HJ, Clayton T, Das D, ... ... Lesley S, et al. The structure of Jann_2411 (DUF1470) from Jannaschia sp. at 1.45 Å resolution reveals a new fold (the ABATE domain) and suggests its possible role as a transcription regulator. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 1198-204. PMID 20944211 DOI: 10.1107/S1744309109025196  0.308
2010 Das D, Finn RD, Abdubek P, Astakhova T, Axelrod HL, Bakolitsa C, Cai X, Carlton D, Chen C, Chiu HJ, Chiu M, Clayton T, Deller MC, Duan L, Ellrott K, ... ... Lesley SA, et al. The crystal structure of a bacterial Sufu-like protein defines a novel group of bacterial proteins that are similar to the N-terminal domain of human Sufu. Protein Science : a Publication of the Protein Society. 19: 2131-40. PMID 20836087 DOI: 10.1002/Pro.497  0.313
2010 Spraggon G, Koesema E, Scarselli M, Malito E, Biagini M, Norais N, Emolo C, Barocchi MA, Giusti F, Hilleringmann M, Rappuoli R, Lesley S, Covacci A, Masignani V, Ferlenghi I. Supramolecular organization of the repetitive backbone unit of the Streptococcus pneumoniae pilus Plos One. 5. PMID 20559564 DOI: 10.1371/Journal.Pone.0010919  0.304
2010 Gonzalez R, Jennings LL, Knuth M, Orth AP, Klock HE, Ou W, Feuerhelm J, Hull MV, Koesema E, Wang Y, Zhang J, Wu C, Cho CY, Su AI, Batalov S, ... ... Lesley SA, et al. Screening the mammalian extracellular proteome for regulators of embryonic human stem cell pluripotency. Proceedings of the National Academy of Sciences of the United States of America. 107: 3552-7. PMID 20133595 DOI: 10.1073/Pnas.0914019107  0.721
2009 Wikoff WR, Anfora AT, Liu J, Schultz PG, Lesley SA, Peters EC, Siuzdak G. Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites. Proceedings of the National Academy of Sciences of the United States of America. 106: 3698-703. PMID 19234110 DOI: 10.1073/Pnas.0812874106  0.4
2009 Das D, Krishna SS, McMullan D, Miller MD, Xu Q, Abdubek P, Acosta C, Astakhova T, Axelrod HL, Burra P, Carlton D, Chiu HJ, Clayton T, Deller MC, Duan L, ... ... Lesley SA, et al. Crystal structure of the Fic (Filamentation induced by cAMP) family protein SO4266 (gi|24375750) from Shewanella oneidensis MR-1 at 1.6 A resolution. Proteins. 75: 264-71. PMID 19127588 DOI: 10.1002/Prot.22338  0.331
2008 Kozbial P, Xu Q, Chiu HJ, McMullan D, Krishna SS, Miller MD, Abdubek P, Acosta C, Astakhova T, Axelrod HL, Carlton D, Clayton T, Deller M, Duan L, Elias Y, ... ... Lesley SA, et al. Crystal structures of MW1337R and lin2004: representatives of a novel protein family that adopt a four-helical bundle fold. Proteins. 71: 1589-96. PMID 18324683 DOI: 10.1002/Prot.22020  0.32
2008 Gräslund S, Nordlund P, Weigelt J, Hallberg BM, Bray J, Gileadi O, Knapp S, Oppermann U, Arrowsmith C, Hui R, Ming J, dhe-Paganon S, ... ... Lesley SA, et al. Protein production and purification. Nature Methods. 5: 135-46. PMID 18235434 DOI: 10.1038/Nmeth.F.202  0.687
2008 Graziano JJ, Liu W, Perera R, Geierstanger BH, Lesley SA, Schultz PG. Selecting folded proteins from a library of secondary structural elements. Journal of the American Chemical Society. 130: 176-85. PMID 18067292 DOI: 10.1021/Ja074405W  0.762
2008 Klock HE, Koesema EJ, Knuth MW, Lesley SA. Combining the polymerase incomplete primer extension method for cloning and mutagenesis with microscreening to accelerate structural genomics efforts. Proteins. 71: 982-94. PMID 18004753 DOI: 10.1002/prot.21786  0.33
2007 Inagaki H, Tsuruoka H, Hornsby M, Lesley SA, Spraggon G, Ellman JA. Characterization and optimization of selective, nonpeptidic inhibitors of cathepsin S with an unprecedented binding mode. Journal of Medicinal Chemistry. 50: 2693-9. PMID 17469812 DOI: 10.1021/Jm070111+  0.453
2006 Patterson AW, Wood WJ, Hornsby M, Lesley S, Spraggon G, Ellman JA. Identification of selective, nonpeptidic nitrile inhibitors of cathepsin s using the substrate activity screening method. Journal of Medicinal Chemistry. 49: 6298-307. PMID 17034136 DOI: 10.1021/Jm060701S  0.51
2005 Han S, Zhou V, Pan S, Liu Y, Hornsby M, McMullan D, Klock HE, Haugen J, Lesley SA, Gray N, Caldwell J, Gu XJ. Identification of coumarin derivatives as a novel class of allosteric MEK1 inhibitors. Bioorganic & Medicinal Chemistry Letters. 15: 5467-73. PMID 16199156 DOI: 10.1016/J.Bmcl.2005.08.097  0.381
2005 Wang Y, Klock H, Yin H, Wolff K, Bieza K, Niswonger K, Matzen J, Gunderson D, Hale J, Lesley S, Kuhen K, Caldwell J, Brinker A. Homogeneous high-throughput screening assays for HIV-1 integrase 3beta-processing and strand transfer activities. Journal of Biomolecular Screening. 10: 456-62. PMID 16093555 DOI: 10.1177/1087057105275212  0.675
2005 Kreusch A, Han S, Brinker A, Zhou V, Choi HS, He Y, Lesley SA, Caldwell J, Gu XJ. Crystal structures of human HSP90α-complexed with dihydroxyphenylpyrazoles Bioorganic and Medicinal Chemistry Letters. 15: 1475-1478. PMID 15713410 DOI: 10.1016/J.Bmcl.2004.12.087  0.666
2004 Peti W, Etezady-Esfarjani T, Herrmann T, Klock HE, Lesley SA, Wüthrich K. NMR for structural proteomics of Thermotoga maritima: Screening and structure determination Journal of Structural and Functional Genomics. 5: 205-215. PMID 15263836 DOI: 10.1023/B:Jsfg.0000029055.84242.9F  0.323
2002 Lesley SA, Kuhn P, Godzik A, Deacon AM, Mathews I, Kreusch A, Spraggon G, Klock HE, McMullan D, Shin T, Vincent J, Robb A, Brinen LS, Miller MD, McPhillips TM, et al. Structural genomics of the Thermotoga maritima proteome implemented in a high-throughput structure determination pipeline. Proceedings of the National Academy of Sciences of the United States of America. 99: 11664-9. PMID 12193646 DOI: 10.1073/Pnas.142413399  0.431
2002 Lesley SA, Graziano J, Cho CY, Knuth MW, Klock HE. Gene expression response to misfolded protein as a screen for soluble recombinant protein. Protein Engineering. 15: 153-60. PMID 11917152 DOI: 10.1093/Protein/15.2.153  0.743
2002 Mathews II, Deacon AM, McMullan D, Canaves JM, Kuhn P, Lesley S. Structural insights into the mechanism of thymidylate synthase complementing proteins Acta Crystallographica Section a Foundations of Crystallography. 58: c106-c106. DOI: 10.1107/S0108767302089286  0.376
1993 Lesley SA, Patten PA, Schultz PG. A genetic approach to the generation of antibodies with enhanced catalytic activities. Proceedings of the National Academy of Sciences of the United States of America. 90: 1160-5. PMID 8094556 DOI: 10.1073/Pnas.90.4.1160  0.742
1992 Gong B, Lesley SA, Schultz PG. A chromogenic assay for screening large antibody libraries Journal of the American Chemical Society. 114: 1486-1487. DOI: 10.1021/Ja00030A056  0.568
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