| Year |
Citation |
Score |
| 2023 |
Zhang PP, Benske TM, Ahn LY, Schaffer AE, Paton JC, Paton AW, Mu TW, Wang YJ. Adapting the endoplasmic reticulum proteostasis rescues epilepsy-associated NMDA receptor variants. Acta Pharmacologica Sinica. PMID 37803141 DOI: 10.1038/s41401-023-01172-w |
0.305 |
|
| 2022 |
Wang M, Cotter E, Wang YJ, Fu X, Whittsette AL, Lynch JW, Wiseman RL, Kelly JW, Keramidas A, Mu TW. Pharmacological activation of ATF6 remodels the proteostasis network to rescue pathogenic GABA receptors. Cell & Bioscience. 12: 48. PMID 35477478 DOI: 10.1186/s13578-022-00783-w |
0.545 |
|
| 2020 |
Di XJ, Wang YJ, Cotter E, Wang M, Whittsette AL, Han DY, Sangwung P, Brown R, Lynch JW, Keramidas A, Mu TW. Proteostasis Regulators Restore Function of Epilepsy-Associated GABA Receptors. Cell Chemical Biology. PMID 32888501 DOI: 10.1016/J.Chembiol.2020.08.012 |
0.414 |
|
| 2019 |
Wang YJ, Mu TW. Interactome Changes Quantified to Identify the ER Proteostasis Network to Fight Amyloid Diseases. Cell Chemical Biology. 26: 909-910. PMID 31323219 DOI: 10.1016/J.Chembiol.2019.07.003 |
0.308 |
|
| 2019 |
Fu YL, Zhang B, Mu TW. LMAN1 (ERGIC-53) promotes trafficking of neuroreceptors. Biochemical and Biophysical Research Communications. PMID 30791981 DOI: 10.1016/J.Bbrc.2019.02.053 |
0.407 |
|
| 2018 |
Fu YL, Han DY, Wang YJ, Di XJ, Yu HB, Mu TW. Remodeling the endoplasmic reticulum proteostasis network restores proteostasis of pathogenic GABAA receptors. Plos One. 13: e0207948. PMID 30481215 DOI: 10.1371/Journal.Pone.0207948 |
0.446 |
|
| 2016 |
Fu YL, Wang YJ, Mu TW. Proteostasis Maintenance of Cys-Loop Receptors. Advances in Protein Chemistry and Structural Biology. 103: 1-23. PMID 26920686 DOI: 10.1016/Bs.Apcsb.2015.11.002 |
0.349 |
|
| 2015 |
Han DY, Guan BJ, Wang YJ, Hatzoglou M, Mu TW. L-type Calcium Channel Blockers Enhance Trafficking and Function of Epilepsy-associated α1(D219N) Subunits of GABAA Receptors. Acs Chemical Biology. PMID 26168288 DOI: 10.1021/Acschembio.5B00479 |
0.408 |
|
| 2015 |
Han DY, Di XJ, Fu YL, Mu TW. Combining valosin-containing protein (VCP) inhibition and suberanilohydroxamic acid (SAHA) treatment additively enhances the folding, trafficking, and function of epilepsy-associated γ-aminobutyric acid, type A (GABAA) receptors. The Journal of Biological Chemistry. 290: 325-37. PMID 25406314 DOI: 10.1074/Jbc.M114.580324 |
0.412 |
|
| 2014 |
Wang YJ, Tayo BO, Bandyopadhyay A, Wang H, Feng T, Franceschini N, Tang H, Gao J, Sung YJ, Elston RC, Williams SM, Cooper RS, Mu TW, Zhu X. The association of the vanin-1 N131S variant with blood pressure is mediated by endoplasmic reticulum-associated degradation and loss of function. Plos Genetics. 10: e1004641. PMID 25233454 DOI: 10.1371/Journal.Pgen.1004641 |
0.545 |
|
| 2014 |
Wang YJ, Di XJ, Mu TW. Using pharmacological chaperones to restore proteostasis. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 83: 3-9. PMID 24747662 DOI: 10.1016/j.phrs.2014.04.002 |
0.304 |
|
| 2013 |
Di XJ, Han DY, Wang YJ, Chance MR, Mu TW. SAHA enhances Proteostasis of epilepsy-associated α1(A322D)β2γ2 GABA(A) receptors. Chemistry & Biology. 20: 1456-68. PMID 24211135 DOI: 10.1016/J.Chembiol.2013.09.020 |
0.361 |
|
| 2013 |
Ong DS, Wang YJ, Tan YL, Yates JR, Mu TW, Kelly JW. FKBP10 depletion enhances glucocerebrosidase proteostasis in Gaucher disease fibroblasts. Chemistry & Biology. 20: 403-15. PMID 23434032 DOI: 10.1016/J.Chembiol.2012.11.014 |
0.533 |
|
| 2010 |
Ong DS, Mu TW, Palmer AE, Kelly JW. Endoplasmic reticulum Ca2+ increases enhance mutant glucocerebrosidase proteostasis. Nature Chemical Biology. 6: 424-32. PMID 20453863 DOI: 10.1038/Nchembio.368 |
0.487 |
|
| 2008 |
Mu TW, Ong DS, Wang YJ, Balch WE, Yates JR, Segatori L, Kelly JW. Chemical and biological approaches synergize to ameliorate protein-folding diseases. Cell. 134: 769-81. PMID 18775310 DOI: 10.1016/J.Cell.2008.06.037 |
0.631 |
|
| 2008 |
Mu TW, Fowler DM, Kelly JW. Partial restoration of mutant enzyme homeostasis in three distinct lysosomal storage disease cell lines by altering calcium homeostasis. Plos Biology. 6: e26. PMID 18254660 DOI: 10.1371/Journal.Pbio.0060026 |
0.619 |
|
| 2003 |
Mu TW, Lester HA, Dougherty DA. Different binding orientations for the same agonist at homologous receptors: a lock and key or a simple wedge? Journal of the American Chemical Society. 125: 6850-1. PMID 12783521 DOI: 10.1021/Ja0348086 |
0.424 |
|
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