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James Leahy - Publications

Affiliations: 
1992-1998 Department of Chemistry University of California, Berkeley, Berkeley, CA, United States 
 2012- Department of Chemistry University of South Florida, Tampa, FL, United States 
Area:
organic chemistry, medicinal chemistry
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33 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Hill SE, Beaulieu-Abdelahad D, Lemus A, Webster JM, Ospina SR, Darling AL, Martin MD, Patel S, Bridenstine L, Swonger R, Paul S, Blackburn R, Calcul L, Dickey CA, Leahy JW, et al. . Acs Chemical Biology. PMID 37144894 DOI: 10.1021/acschembio.2c00919  0.598
2018 Sabbagh JJ, Cordova RA, Zheng D, Criado-Marrero M, Lemus A, Li P, Baker JD, Nordhues BA, Darling AL, Martinez-Licha C, Rutz DA, Patel S, Buchner J, Leahy JW, Koren J, et al. Targeting the FKBP51/GR/Hsp90 complex to identify functionally relevant treatments for depression and PTSD. Acs Chemical Biology. PMID 29893552 DOI: 10.1021/Acschembio.8B00454  0.626
2018 Shultz ZP, Lawrence GA, Jacobson JM, Cruz EJ, Leahy JW. Enantioselective Total Synthesis of Cannabinoids-A Route for Analogue Development. Organic Letters. PMID 29293352 DOI: 10.1021/acs.orglett.7b03668  0.783
2018 Leahy JW, Carroll DC, McElhone KE. A synthetic approach to the phorboxazoles – A strategy for the synthesis of the C1–C19 polyketide fragment Tetrahedron Letters. 59: 117-120. DOI: 10.1016/J.TETLET.2017.12.007  0.308
2017 Dempsey DR, Nichols DA, Battistini MR, Pemberton O, Ospina SR, Zhang X, Carpenter AM, O'Flynn BG, Leahy JW, Kanwar A, Lewandowski EM, Chen Y, Merkler DJ. Structural and Mechanistic Analysis of Drosophila melanogaster Agmatine N-Acetyltransferase, an Enzyme that Catalyzes the Formation of N-Acetylagmatine. Scientific Reports. 7: 13432. PMID 29044148 DOI: 10.1038/S41598-017-13669-6  0.548
2017 Giulianotti MA, Vesely BA, Azhari A, Souza A, LaVoi T, Houghten RA, Kyle DE, Leahy JW. Identification of a Hit Series of Antileishmanial Compounds through the Use of Mixture-Based Libraries. Acs Medicinal Chemistry Letters. 8: 802-807. PMID 28835792 DOI: 10.1021/acsmedchemlett.7b00045  0.594
2017 Kanwar A, Eduful BJ, Barbeto L, Carletti Bonomo P, Lemus A, Vesely BA, Mutka TS, Azhari A, Kyle DE, Leahy JW. Synthesis and Activity of a New Series of Antileishmanial Agents. Acs Medicinal Chemistry Letters. 8: 797-801. PMID 28835791 DOI: 10.1021/Acsmedchemlett.7B00039  0.599
2016 Shultz Z, Leahy JW. Synthesis of the phorboxazoles-potent, architecturally novel marine natural products. The Journal of Antibiotics. 69: 220-52. PMID 26956795 DOI: 10.1038/Ja.2016.8  0.782
2010 Lafontaine JA, Provencal DP, Gardelli C, Leahy JW. ChemInform Abstract: The Enantioselective Total Synthesis of the Antitumor Macrolide Natural Product Rhizoxin D. Cheminform. 30: no-no. DOI: 10.1002/CHIN.199932257  0.746
2010 BOYER SJ, LEAHY JW. ChemInform Abstract: Carbocyclic Nucleoside Analogues. Part 1. Concise Enantioselective Synthesis of Functionalized Cyclopentanes and Formal Total Synthesis of Aristeromycin. Cheminform. 28: no-no. DOI: 10.1002/CHIN.199744256  0.404
2010 SMITH ABI, CONDON SM, MCCAULEY JA, LEAZER JLJ, LEAHY JW, MALECZKA REJ. ChemInform Abstract: A Unified Total Synthesis of the Immunomodulators (-)-Rapamycin and (-) -27-Demethoxyrapamycin: Assembly of the Common C(1-20) Perimeter and Final Elaboration. Cheminform. 28: no-no. DOI: 10.1002/chin.199719249  0.387
2010 SMITH ABI, CONDON SM, MCCAULEY JA, LEAZER JLJ, LEAHY JW, MALECZKA REJ. ChemInform Abstract: A Unified Total Synthesis of the Immunomodulators (-)-Rapamycin and (-) -27-Demethoxyrapamycin: Construction of the C(21-42) Perimeters. Cheminform. 28: no-no. DOI: 10.1002/chin.199719248  0.403
2010 PROVENCAL DP, GARDELLI C, LAFONTAINE JA, LEAHY JW. ChemInform Abstract: Rhizoxin Synthetic Studies. Part 2. Synthesis of the Left Hand (C(10) to C(19)) and Polyene Fragments. Cheminform. 26: no-no. DOI: 10.1002/chin.199550215  0.746
2010 LAFONTAINE JA, LEAHY JW. ChemInform Abstract: Rhizoxin Synthetic Studies. Part 1. Synthesis of the Right Hand (C(1) to C(9)) Portion via a “Pinwheel” Approach. Cheminform. 26: no-no. DOI: 10.1002/CHIN.199550214  0.749
2010 HIRSCHMANN R, SPRENGELER PA, KAWASAKI T, LEAHY JW, SHAKESPEARE WC, SMITH ABI. ChemInform Abstract: The Versatile Steroid Nucleus: Design and Synthesis of a Peptidomimetic Employing This Novel Scaffold. Cheminform. 24: no-no. DOI: 10.1002/chin.199334260  0.327
2010 HIRSCHMANN R, SPRENGELER PA, KAWASAKI T, LEAHY JW, SHAKESPEARE WC, SMITH ABI. ChemInform Abstract: The First Design and Synthesis of a Steroidal Peptidomimetic. The Potential Value of Peptidomimetics in Elucidating the Bioactive Conformation of Peptide Ligands. Cheminform. 24: no-no. DOI: 10.1002/chin.199314252  0.623
2010 SMITH ABI, LEAHY JW, NODA I, REMISZEWSKI SW, LIVERTON NJ, ZIBUCK R. ChemInform Abstract: Total Synthesis of the Latrunculins. Cheminform. 23: no-no. DOI: 10.1002/chin.199232253  0.369
2003 Lafontaine JA, Provencal DP, Gardelli C, Leahy JW. Enantioselective total synthesis of the antitumor macrolide rhizoxin D. The Journal of Organic Chemistry. 68: 4215-34. PMID 12762720 DOI: 10.1021/jo034011x  0.72
2002 Folkes A, Brown SD, Canne LE, Chan J, Engelhardt E, Epshteyn S, Faint R, Golec J, Hanel A, Kearney P, Leahy JW, Mac M, Matthews D, Prisbylla MP, Sanderson J, et al. Design, synthesis and in vitro evaluation of potent, novel, small molecule inhibitors of plasminogen activator inhibitor-1. Bioorganic & Medicinal Chemistry Letters. 12: 1063-6. PMID 11909718 DOI: 10.1016/S0960-894X(02)00078-1  0.337
1999 Lafontaine JA, Provencal DP, Gardelli C, Leahy JW. The enantioselective total synthesis of the antitumor macrolide natural product rhizoxin D Tetrahedron Letters. 40: 4145-4148. DOI: 10.1016/S0040-4039(99)00731-5  0.742
1997 Gardinier KM, Leahy JW. Enantiospecific Total Synthesis of the Potent Antitumor Macrolides Cryptophycins 1 and 8. The Journal of Organic Chemistry. 62: 7098-7099. PMID 11671811  0.799
1997 Boyer SJ, Leahy JW. Carbocyclic Nucleoside Analogs. 1. Concise Enantioselective Synthesis of Functionalized Cyclopentanes and Formal Total Synthesis of Aristeromycin The Journal of Organic Chemistry. 62: 3976-3980. DOI: 10.1021/jo970153d  0.393
1997 Smith AB, Condon SM, McCauley JA, Leazer JL, Leahy JW, Maleczka RE. A unified total synthesis of the immunomodulators (-)-rapamycin and (-)-27-demethoxyrapamycin: Assembly of the common C(1-20) perimeter and final elaboration Journal of the American Chemical Society. 119: 962-973. DOI: 10.1021/Ja963067O  0.679
1997 Smith AB, Condon SM, McCauley JA, Leazer JL, Leahy JW, Maleczka RE. A unified total synthesis of the immunomodulators (-)-rapamycin and (-)-27-demethoxyrapamycin: Construction of the C(21-42) perimeters Journal of the American Chemical Society. 119: 947-961. DOI: 10.1021/Ja963066W  0.672
1995 Smith AB, Condon SM, McCauley JA, Leazer JL, Leahy JW, Maleczka RE. Total synthesis of rapamycin and demethoxyrapamycin Journal of the American Chemical Society. 117: 5407-5408. DOI: 10.1021/Ja00124A043  0.66
1995 Provencal DP, Gardelli C, Lafontaine JA, Leahy JW. Rhizoxin synthetic studies. 2. Synthesis of the left hand [C(10) to C(19)] and polyene fragments Tetrahedron Letters. 36: 6033-6036. DOI: 10.1016/0040-4039(95)01194-M  0.742
1995 Lafontaine JA, Leahy JW. Rhizoxin synthetic studies. 1. Synthesis of the right hand [C(1) to C(9)]portion via a “pinwheel” approach Tetrahedron Letters. 36: 6029-6032. DOI: 10.1016/0040-4039(95)01193-L  0.744
1994 Smith AB, Maleczka RE, Leazer JL, Leahy JW, McCauley JA, Condon SM. Rapamycin synthetic studies. 2. Elaboration of the C(10)-C(26) perimeter Tetrahedron Letters. 35: 4911-4914. DOI: 10.1016/S0040-4039(00)73280-1  0.618
1994 Smith AB, Condon SM, McCauley JA, Leahy JW, Leazer JL, Maleczka RE. Rapamycin synthetic studies. 1. Construction of the C(27)-C(42) subunit Tetrahedron Letters. 35: 4907-4910. DOI: 10.1016/S0040-4039(00)73279-5  0.611
1993 Hirschmann R, Sprengeler PA, Kawasaki T, Leahy JW, Shakespeare WC, Smith AB. The versatile steroid nucleus: Design and synthesis of a peptidomimetic employing this novel scaffold. Tetrahedron. 49: 3665-3676. DOI: 10.1016/S0040-4020(01)90222-4  0.64
1992 Hirschmann R, Sprengeler PA, Kawasaki T, Leahy JW, Shakespeare WC, Smith AB. The first design and synthesis of a steroidal peptidomimetic. The potential value of peptidomimetics in elucidating the bioactive conformation of peptide ligands Journal of the American Chemical Society. 114: 9699-9701. DOI: 10.1021/Ja00050A082  0.617
1992 Smith AB, Leahy JW, Noda I, Remiszewski SW, Liverton NJ, Zibuck R. Total synthesis of the latrunculins Journal of the American Chemical Society. 114: 2995-3007. DOI: 10.1021/ja00034a036  0.374
1989 Leahy J, Schneller S. The Synthesis of the Carbocyclic Derivative of lin-Benzo-Separated 2',3'-Dideoxyinosine Nucleosides, Nucleotides and Nucleic Acids. 8: 1081-1082. DOI: 10.1080/07328318908054289  0.622
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