| Year |
Citation |
Score |
| 2018 |
Wójcik S, Birol M, Rhoades E, Miranker AD, Levine ZA. Targeting the Intrinsically Disordered Proteome Using Small-Molecule Ligands. Methods in Enzymology. 611: 703-734. PMID 30471705 DOI: 10.1016/Bs.Mie.2018.09.036 |
0.317 |
|
| 2018 |
Birol M, Kumar S, Rhoades E, Miranker AD. Conformational switching within dynamic oligomers underpins toxic gain-of-function by diabetes-associated amyloid. Nature Communications. 9: 1312. PMID 29615609 DOI: 10.1038/S41467-018-03651-9 |
0.463 |
|
| 2017 |
Birol M, Kumar S, Rhoades E, Miranker A. Toxic and Non-Toxic Forms of Membrane Poration are Mediated by Structurally Distinct States of Islet Amyloid Polypeptide Biophysical Journal. 112: 503a. DOI: 10.1016/J.Bpj.2016.11.2724 |
0.449 |
|
| 2016 |
Kumar S, Birol M, Schlamadinger DE, Wojcik SP, Rhoades E, Miranker AD. Foldamer-mediated manipulation of a pre-amyloid toxin. Nature Communications. 7: 11412. PMID 27108700 DOI: 10.1038/Ncomms11412 |
0.5 |
|
| 2016 |
Kumar S, Birol M, Miranker AD. Foldamer scaffolds suggest distinct structures are associated with alternative gains-of-function in a preamyloid toxin. Chemical Communications (Cambridge, England). PMID 27079937 DOI: 10.1039/C6Cc01248E |
0.401 |
|
| 2016 |
Junghans A, Watkins EB, Majewski J, Miranker AD, Stroe I. Influence of the Human and Rat Islet Amyloid Polypeptides on Structure of Phospholipid Bilayers: Neutron Reflectometry and Fluorescence Microscopy Studies. Langmuir : the Acs Journal of Surfaces and Colloids. PMID 27065348 DOI: 10.1021/Acs.Langmuir.6B00825 |
0.501 |
|
| 2016 |
Khemtemourian L, Gazit E, Miranker A. Recent Insight in Islet Amyloid Polypeptide Morphology, Structure, Membrane Interaction, and Toxicity in Type 2 Diabetes. Journal of Diabetes Research. 2016: 2535878. PMID 26770986 DOI: 10.1155/2016/2535878 |
0.366 |
|
| 2015 |
White EM, Miranker AD. A solenoid design for assessing determinants of parallel β-sheet registration. Protein Engineering, Design & Selection : Peds. PMID 26487712 DOI: 10.1093/Protein/Gzv053 |
0.349 |
|
| 2015 |
Witten J, Ruschak A, Poterba T, Jaramillo A, Miranker AD, Jaswal SS. Mapping Protein Conformational Landscapes under Strongly Native Conditions with Hydrogen Exchange Mass Spectrometry. The Journal of Physical Chemistry. B. 119: 10016-24. PMID 26146955 DOI: 10.1021/Acs.Jpcb.5B04528 |
0.789 |
|
| 2015 |
Nath A, Schlamadinger DE, Rhoades E, Miranker AD. Structure-Based Small Molecule Modulation of a Pre-Amyloid State: Pharmacological Enhancement of IAPP Membrane-Binding and Toxicity. Biochemistry. 54: 3555-64. PMID 25966003 DOI: 10.1021/Acs.Biochem.5B00052 |
0.443 |
|
| 2015 |
Kumar S, Schlamadinger DE, Brown MA, Dunn JM, Mercado B, Hebda JA, Saraogi I, Rhoades E, Hamilton AD, Miranker AD. Islet amyloid-induced cell death and bilayer integrity loss share a molecular origin targetable with oligopyridylamide-based α-helical mimetics. Chemistry & Biology. 22: 369-78. PMID 25754474 DOI: 10.1016/J.Chembiol.2015.01.006 |
0.794 |
|
| 2015 |
Rubio MA, Schlamadinger DE, White EM, Miranker AD. Peptide amyloid surface display. Biochemistry. 54: 987-93. PMID 25541905 DOI: 10.1021/Bi5011442 |
0.662 |
|
| 2015 |
Kulikov OV, Kumar S, Magzoub M, Knipe PC, Saraogi I, Thompson S, Miranker AD, Hamilton AD. Amphiphilic oligoamide α-helix peptidomimetics inhibit islet amyloid polypeptide aggregation Tetrahedron Letters. DOI: 10.1016/J.Tetlet.2015.02.132 |
0.499 |
|
| 2015 |
Brown MA, Rhoades E, Miranker AD. A Role for Unstructured Residues in the Induction of Membrane Poration by Pre-Amyloid Assemblies of Islet Amyloid Polypeptide Biophysical Journal. 108: 496a. DOI: 10.1016/J.Bpj.2014.11.2712 |
0.486 |
|
| 2015 |
Kumar S, Schlamadinger D, Miranker A. Foldamer-Based Enantioselective Targeting of Islet Amyloid Polypeptide Biophysical Journal. 108: 217a. DOI: 10.1016/J.Bpj.2014.11.1198 |
0.553 |
|
| 2014 |
Schlamadinger DE, Miranker AD. Fiber-dependent and -independent toxicity of islet amyloid polypeptide. Biophysical Journal. 107: 2559-66. PMID 25468335 DOI: 10.1016/J.Bpj.2014.09.047 |
0.494 |
|
| 2014 |
Hebda JA, Magzoub M, Miranker AD. Small molecule screening in context: lipid-catalyzed amyloid formation. Protein Science : a Publication of the Protein Society. 23: 1341-8. PMID 25043951 DOI: 10.1002/Pro.2518 |
0.82 |
|
| 2014 |
Kumar S, Brown MA, Nath A, Miranker AD. Folded small molecule manipulation of islet amyloid polypeptide. Chemistry & Biology. 21: 775-81. PMID 24930968 DOI: 10.1016/J.Chembiol.2014.05.007 |
0.497 |
|
| 2014 |
Rubio M, Miranker AD. Surface-Catalyzed Nucleation of Amyloidogenic Peptides by Peptide-Specific Templates Biophysical Journal. 106: 39a. DOI: 10.1016/J.Bpj.2013.11.293 |
0.683 |
|
| 2013 |
Last NB, Schlamadinger DE, Miranker AD. A common landscape for membrane-active peptides. Protein Science : a Publication of the Protein Society. 22: 870-82. PMID 23649542 DOI: 10.1002/Pro.2274 |
0.782 |
|
| 2013 |
Kumar S, Miranker AD. A foldamer approach to targeting membrane bound helical states of islet amyloid polypeptide. Chemical Communications (Cambridge, England). 49: 4749-51. PMID 23579860 DOI: 10.1039/C3Cc41452C |
0.498 |
|
| 2013 |
Last NB, Miranker AD. Common mechanism unites membrane poration by amyloid and antimicrobial peptides. Proceedings of the National Academy of Sciences of the United States of America. 110: 6382-7. PMID 23576726 DOI: 10.1073/Pnas.1219059110 |
0.795 |
|
| 2013 |
Nath A, Schlamadinger DE, Dodhia S, Rhoades E, Miranker AD. Screening and Design of New Modulators of IAPP Membrane-Binding and Toxicity Biophysical Journal. 104: 56a-57a. DOI: 10.1016/J.Bpj.2012.11.351 |
0.494 |
|
| 2013 |
Schlamadinger DE, Kumar S, Magzoub M, Hebda JA, Miranker AD. Inhibition and Mechanism of Islet Amyloid Polypeptide Toxicity Biophysical Journal. 104: 56a. DOI: 10.1016/J.Bpj.2012.11.350 |
0.809 |
|
| 2013 |
Dodhia S, Nath A, Miranker AD. Design and Characterization of Peptide Modulators of IAPP-Membrane Binding Biophysical Journal. 104: 592a. DOI: 10.1016/J.Bpj.2012.11.3288 |
0.463 |
|
| 2013 |
Dunn JM, Miranker AD, Rhoades E. Membrane Geometry Alters the Interaction between Islet Amyloid Polypeptide and Lipid Bilayers Biophysical Journal. 104: 592a. DOI: 10.1016/J.Bpj.2012.11.3287 |
0.424 |
|
| 2013 |
White EM, Kishore Inampudi K, Wilson CJ, Miranker AD. Designing Self Assembling Beta Helices Biophysical Journal. 104: 568a-569a. DOI: 10.1016/J.Bpj.2012.11.3155 |
0.438 |
|
| 2013 |
Kumar S, Schlamadinger DE, Miranker A. Targeting Protein Misfolding(Islet Amyloid Polypeptide) using Helical Mimetics Biophysical Journal. 104: 379a. DOI: 10.1016/J.Bpj.2012.11.2112 |
0.504 |
|
| 2012 |
Magzoub M, Miranker AD. Concentration-dependent transitions govern the subcellular localization of islet amyloid polypeptide. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 1228-38. PMID 22183778 DOI: 10.1096/Fj.11-194613 |
0.456 |
|
| 2011 |
Nath A, Miranker AD, Rhoades E. A membrane-bound antiparallel dimer of rat islet amyloid polypeptide. Angewandte Chemie (International Ed. in English). 50: 10859-62. PMID 21948544 DOI: 10.1002/Anie.201102887 |
0.442 |
|
| 2011 |
Last NB, Rhoades E, Miranker AD. Islet amyloid polypeptide demonstrates a persistent capacity to disrupt membrane integrity. Proceedings of the National Academy of Sciences of the United States of America. 108: 9460-5. PMID 21606325 DOI: 10.1073/Pnas.1102356108 |
0.817 |
|
| 2011 |
Magzoub M, Miranker AD. Protein aggregation: p53 succumbs to peer pressure. Nature Chemical Biology. 7: 248-9. PMID 21502944 DOI: 10.1038/Nchembio.569 |
0.328 |
|
| 2011 |
Nath A, O'Hern C, Miranker AD, Rhoades E. Single molecule studies of unstructured protein function and dynamics Optics Infobase Conference Papers. DOI: 10.1364/Fio.2011.Ftuh1 |
0.341 |
|
| 2011 |
Last NB, Rhoades E, Miranker AD. Evolution of Membrane Leakage by Pre-Amyloidogenic Oligomers of Islet Amyloid Polypeptide Biophysical Journal. 100: 350a. DOI: 10.1016/J.Bpj.2010.12.2110 |
0.495 |
|
| 2010 |
Wolfe LS, Calabrese MF, Nath A, Blaho DV, Miranker AD, Xiong Y. Protein-induced photophysical changes to the amyloid indicator dye thioflavin T. Proceedings of the National Academy of Sciences of the United States of America. 107: 16863-8. PMID 20826442 DOI: 10.1073/Pnas.1002867107 |
0.777 |
|
| 2010 |
Nath A, Trexler AJ, Koo P, Miranker AD, Atkins WM, Rhoades E. Single-molecule fluorescence spectroscopy using phospholipid bilayer nanodiscs. Methods in Enzymology. 472: 89-117. PMID 20580961 DOI: 10.1016/S0076-6879(10)72014-0 |
0.381 |
|
| 2010 |
Saraogi I, Hebda JA, Becerril J, Estroff LA, Miranker AD, Hamilton AD. Synthetic alpha-helix mimetics as agonists and antagonists of islet amyloid polypeptide aggregation. Angewandte Chemie (International Ed. in English). 49: 736-9. PMID 20029853 DOI: 10.1002/Anie.200901694 |
0.807 |
|
| 2010 |
Nath A, Miranker AD, Rhoades E. Pre-Amyloid States of Islet Amyloid Polypeptide Examined by Single-Particle Fluorescence Biophysical Journal. 98: 650a-651a. DOI: 10.1016/J.Bpj.2009.12.3566 |
0.52 |
|
| 2010 |
Magzoub M, Hebda JA, Miranker A. Small Molecule Inhibitors of Islet Amyloid Polypeptide Fibrillogenesis and Cytotoxicity Biophysical Journal. 98: 255a. DOI: 10.1016/J.Bpj.2009.12.1387 |
0.838 |
|
| 2009 |
Hebda JA, Saraogi I, Magzoub M, Hamilton AD, Miranker AD. A peptidomimetic approach to targeting pre-amyloidogenic states in type II diabetes. Chemistry & Biology. 16: 943-50. PMID 19778722 DOI: 10.1016/J.Chembiol.2009.08.013 |
0.82 |
|
| 2009 |
Williamson JA, Loria JP, Miranker AD. Helix stabilization precedes aqueous and bilayer-catalyzed fiber formation in islet amyloid polypeptide. Journal of Molecular Biology. 393: 383-96. PMID 19647750 DOI: 10.1016/J.Jmb.2009.07.077 |
0.733 |
|
| 2009 |
Ruschak AM, Miranker AD. The role of prefibrillar structures in the assembly of a peptide amyloid. Journal of Molecular Biology. 393: 214-26. PMID 19524594 DOI: 10.1016/J.Jmb.2009.06.026 |
0.83 |
|
| 2009 |
Blaho DV, Miranker AD. Delineating the conformational elements responsible for Cu(2+)-induced oligomerization of beta-2 microglobulin. Biochemistry. 48: 6610-7. PMID 19518133 DOI: 10.1021/Bi900540J |
0.791 |
|
| 2009 |
Hebda JA, Miranker AD. The interplay of catalysis and toxicity by amyloid intermediates on lipid bilayers: insights from type II diabetes. Annual Review of Biophysics. 38: 125-52. PMID 19416063 DOI: 10.1146/Annurev.Biophys.050708.133622 |
0.827 |
|
| 2009 |
Calabrese MF, Miranker AD. Metal binding sheds light on mechanisms of amyloid assembly. Prion. 3: 1-4. PMID 19377278 DOI: 10.4161/Pri.3.1.8601 |
0.762 |
|
| 2009 |
Last NB, Rhoades E, Miranker AD. Single Particle Analysis of Liposome Leakage Induced by Islet Amyloid Polypeptide Biophysical Journal. 96: 158a. DOI: 10.1016/J.Bpj.2008.12.718 |
0.472 |
|
| 2008 |
Calabrese MF, Eakin CM, Wang JM, Miranker AD. A regulatable switch mediates self-association in an immunoglobulin fold. Nature Structural & Molecular Biology. 15: 965-71. PMID 19172750 DOI: 10.1038/Nsmb.1483 |
0.813 |
|
| 2008 |
Knight JD, Williamson JA, Miranker AD. Interaction of membrane-bound islet amyloid polypeptide with soluble and crystalline insulin. Protein Science : a Publication of the Protein Society. 17: 1850-6. PMID 18765820 DOI: 10.1110/Ps.036350.108 |
0.751 |
|
| 2008 |
Koo BW, Hebda JA, Miranker AD. Amide inequivalence in the fibrillar assembly of islet amyloid polypeptide. Protein Engineering, Design & Selection : Peds. 21: 147-54. PMID 18299291 DOI: 10.1093/Protein/Gzm076 |
0.821 |
|
| 2007 |
Jaswal SS, Miranker AD. Scope and utility of hydrogen exchange as a tool for mapping landscapes. Protein Science : a Publication of the Protein Society. 16: 2378-90. PMID 17962401 DOI: 10.1110/Ps.072994207 |
0.328 |
|
| 2007 |
Ruschak AM, Miranker AD. Fiber-dependent amyloid formation as catalysis of an existing reaction pathway. Proceedings of the National Academy of Sciences of the United States of America. 104: 12341-6. PMID 17640888 DOI: 10.1073/Pnas.0703306104 |
0.819 |
|
| 2007 |
Calabrese MF, Miranker AD. Formation of a stable oligomer of beta-2 microglobulin requires only transient encounter with Cu(II). Journal of Molecular Biology. 367: 1-7. PMID 17254602 DOI: 10.1016/J.Jmb.2006.12.034 |
0.781 |
|
| 2007 |
Williamson JA, Miranker AD. Direct detection of transient alpha-helical states in islet amyloid polypeptide. Protein Science : a Publication of the Protein Society. 16: 110-7. PMID 17123962 DOI: 10.1110/Ps.062486907 |
0.697 |
|
| 2007 |
Williamson J, Miranker A. Backbone 1H, 13C, and 15N and CB Assignments for Rat Islet Amyloid Polypeptide Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr7311 |
0.578 |
|
| 2006 |
Knight JD, Hebda JA, Miranker AD. Conserved and cooperative assembly of membrane-bound alpha-helical states of islet amyloid polypeptide. Biochemistry. 45: 9496-508. PMID 16878984 DOI: 10.1021/Bi060579Z |
0.833 |
|
| 2006 |
Eakin CM, Berman AJ, Miranker AD. A native to amyloidogenic transition regulated by a backbone trigger. Nature Structural & Molecular Biology. 13: 202-8. PMID 16491088 DOI: 10.1038/Nsmb1068 |
0.753 |
|
| 2005 |
Eakin CM, Miranker AD. From chance to frequent encounters: origins of beta2-microglobulin fibrillogenesis. Biochimica Et Biophysica Acta. 1753: 92-9. PMID 16226064 DOI: 10.1016/J.Bbapap.2005.09.002 |
0.745 |
|
| 2005 |
Miranker AD. Structural biology: fibres hinge on swapped domains. Nature. 437: 197-8. PMID 16148916 DOI: 10.1038/437197A |
0.328 |
|
| 2005 |
Miranker AD. Quantitative measurement of fibrillogenesis by mass spectrometry. Methods in Molecular Biology (Clifton, N.J.). 299: 185-94. PMID 15980602 DOI: 10.1385/1-59259-874-9:185 |
0.444 |
|
| 2005 |
Koo BW, Miranker AD. Contribution of the intrinsic disulfide to the assembly mechanism of islet amyloid. Protein Science : a Publication of the Protein Society. 14: 231-9. PMID 15576552 DOI: 10.1110/Ps.041051205 |
0.741 |
|
| 2004 |
Knight JD, Miranker AD. Phospholipid catalysis of diabetic amyloid assembly. Journal of Molecular Biology. 341: 1175-87. PMID 15321714 DOI: 10.1016/J.Jmb.2004.06.086 |
0.702 |
|
| 2004 |
Eakin CM, Attenello FJ, Morgan CJ, Miranker AD. Oligomeric assembly of native-like precursors precedes amyloid formation by beta-2 microglobulin. Biochemistry. 43: 7808-15. PMID 15196023 DOI: 10.1021/Bi049792Q |
0.75 |
|
| 2004 |
Miranker AD. Unzipping the mysteries of amyloid fiber formation. Proceedings of the National Academy of Sciences of the United States of America. 101: 4335-6. PMID 15070716 DOI: 10.1073/Pnas.0401163101 |
0.537 |
|
| 2004 |
Larson JL, Miranker AD. The mechanism of insulin action on islet amyloid polypeptide fiber formation. Journal of Molecular Biology. 335: 221-31. PMID 14659752 DOI: 10.1016/J.Jmb.2003.10.045 |
0.412 |
|
| 2002 |
Eakin CM, Knight JD, Morgan CJ, Gelfand MA, Miranker AD. Formation of a copper specific binding site in non-native states of beta-2-microglobulin. Biochemistry. 41: 10646-56. PMID 12186550 DOI: 10.1021/Bi025944A |
0.755 |
|
| 2002 |
Padrick SB, Miranker AD. Islet amyloid: phase partitioning and secondary nucleation are central to the mechanism of fibrillogenesis. Biochemistry. 41: 4694-703. PMID 11926832 DOI: 10.1021/Bi0160462 |
0.759 |
|
| 2001 |
Morgan CJ, Gelfand M, Atreya C, Miranker AD. Kidney dialysis-associated amyloidosis: a molecular role for copper in fiber formation. Journal of Molecular Biology. 309: 339-45. PMID 11371157 DOI: 10.1006/Jmbi.2001.4661 |
0.469 |
|
| 2001 |
Padrick SB, Miranker AD. Islet amyloid polypeptide: identification of long-range contacts and local order on the fibrillogenesis pathway. Journal of Molecular Biology. 308: 783-94. PMID 11350174 DOI: 10.1006/Jmbi.2001.4608 |
0.79 |
|
| 2000 |
Miranker AD. Protein complexes and analysis of their assembly by mass spectrometry. Current Opinion in Structural Biology. 10: 601-6. PMID 11042460 DOI: 10.1016/S0959-440X(00)00137-8 |
0.306 |
|
| 2000 |
Larson JL, Ko E, Miranker AD. Direct measurement of islet amyloid polypeptide fibrillogenesis by mass spectrometry. Protein Science : a Publication of the Protein Society. 9: 427-31. PMID 10716196 DOI: 10.1110/Ps.9.2.427 |
0.427 |
|
| 1999 |
Weber-Ban EU, Reid BG, Miranker AD, Horwich AL. Global unfolding of a substrate protein by the Hsp100 chaperone ClpA. Nature. 401: 90-3. PMID 10485712 DOI: 10.1038/43481 |
0.38 |
|
| 1999 |
Canet D, Sunde M, Last AM, Miranker A, Spencer A, Robinson CV, Dobson CM. Mechanistic studies of the folding of human lysozyme and the origin of amyloidogenic behavior in its disease-related variants. Biochemistry. 38: 6419-27. PMID 10350460 DOI: 10.1021/Bi983037T |
0.605 |
|
| 1998 |
Morgan CJ, Miranker A, Dobson CM. Characterization of collapsed states in the early stages of the refolding of hen lysozyme Biochemistry. 37: 8473-8480. PMID 9622499 DOI: 10.1021/Bi9731504 |
0.422 |
|
| 1996 |
Miranker AD, Dobson CM. Collapse and cooperativity in protein folding. Current Opinion in Structural Biology. 6: 31-42. PMID 8696971 DOI: 10.1016/S0959-440X(96)80092-3 |
0.436 |
|
| 1996 |
Miranker A, Robinson CV, Radford SE, Dobson CM. Investigation of protein folding by mass spectrometry. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 10: 93-101. PMID 8566553 DOI: 10.1096/Fasebj.10.1.8566553 |
0.521 |
|
| 1996 |
Miranker A, Kruppa GH, Robinson CV, Aplin RT, Dobson CM. Isotope-Labeling Strategy for the Assignment of Protein Fragments Generated for Mass Spectrometry Journal of the American Chemical Society. 118: 7402-7403. DOI: 10.1021/Ja9531236 |
0.516 |
|
| 1995 |
Hooke SD, Eyles SJ, Miranker A, Radford SE, Robinson CV, Dobson CM. Cooperative Elements in Protein Folding Monitored by Electrospray Ionization Mass Spectrometry Journal of the American Chemical Society. 117: 7548-7549. DOI: 10.1021/Ja00133A030 |
0.748 |
|
| 1993 |
Miranker A, Robinson CV, Radford SE, Aplin RT, Dobson CM. Detection of transient protein folding populations by mass spectrometry. Science (New York, N.Y.). 262: 896-900. PMID 8235611 DOI: 10.1126/Science.8235611 |
0.498 |
|
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