Stephen L Archer, M.D. - Publications

Affiliations: 
2007-2012 Department of Medicine University of Chicago, Chicago, IL 

235 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Mocumbi A, Humbert M, Saxena A, Jing ZC, Sliwa K, Thienemann F, Archer SL, Stewart S. Publisher Correction: Pulmonary hypertension. Nature Reviews. Disease Primers. 10: 5. PMID 38233482 DOI: 10.1038/s41572-024-00493-2  0.337
2024 Mocumbi A, Humbert M, Saxena A, Jing ZC, Sliwa K, Thienemann F, Archer SL, Stewart S. Pulmonary hypertension. Nature Reviews. Disease Primers. 10: 1. PMID 38177157 DOI: 10.1038/s41572-023-00486-7  0.396
2023 Wu D, Jansen-van Vuuren RD, Dasgupta A, Al-Qazazi R, Chen KH, Martin A, Mewburn JD, Alizadeh E, Lima PDA, Jones O, Colpman P, Breault NM, Emon IM, Jedlovčnik L, Zhao YY, ... ... Archer SL, et al. Efficacy of Drpitor1a, a Dynamin-Related Protein 1 inhibitor, in Pulmonary Arterial Hypertension. Biorxiv : the Preprint Server For Biology. PMID 38187628 DOI: 10.1101/2023.12.21.572836  0.382
2023 Prins KW, Durbin J, Archer SL. Complete revascularization of the pulmonary circulation in chronic thromboembolic pulmonary hypertension: value of addressing chronic total occlusions. The Canadian Journal of Cardiology. PMID 38030122 DOI: 10.1016/j.cjca.2023.11.028  0.33
2023 Breault NM, Wu D, Dasgupta A, Chen KH, Archer SL. Acquired disorders of mitochondrial metabolism and dynamics in pulmonary arterial hypertension. Frontiers in Cell and Developmental Biology. 11: 1105565. PMID 36819102 DOI: 10.3389/fcell.2023.1105565  0.337
2022 Hindmarch CCT, Tian L, Xiong PY, Potus F, Bentley RET, Al-Qazazi R, Prins KW, Archer SL. An integrated proteomic and transcriptomic signature of the failing right ventricle in monocrotaline induced pulmonary arterial hypertension in male rats. Frontiers in Physiology. 13: 966454. PMID 36388115 DOI: 10.3389/fphys.2022.966454  0.31
2022 Al-Qazazi R, Lima PDA, Prisco SZ, Potus F, Dasgupta A, Chen KH, Tian L, Bentley RE, Mewburn J, Martin AY, Wu D, Jones O, Maurice DH, Bonnet S, Provencher S, ... ... Archer SL, et al. Macrophage-NLRP3 Activation Promotes Right Ventricle Failure in Pulmonary Arterial Hypertension. American Journal of Respiratory and Critical Care Medicine. PMID 35699679 DOI: 10.1164/rccm.202110-2274OC  0.348
2021 Thenappan T, Weir EK, Prins KW, Pritzker MR, Archer SL. Carvedilol for Treatment of Right Ventricular Dysfunction in Pulmonary Arterial Hypertension. Journal of the American Heart Association. 10: e021518. PMID 34259020 DOI: 10.1161/JAHA.121.021518  0.366
2021 Adão R, Archer SL. Corrigendum to: Scientist on the spot: Exploring the cause and cure for pulmonary arterial hypertension. Cardiovascular Research. PMID 34143877 DOI: 10.1093/cvr/cvab191  0.369
2021 da Costa Adão RM, Archer SL. Scientist on the Spot: Exploring the cause and cure for pulmonary arterial hypertension. Cardiovascular Research. 117: e82-e83. PMID 34021303 DOI: 10.1093/cvr/cvab091  0.369
2020 Xiong PY, Jaff Z, D'Arsigny CL, Archer SL, Wijeratne DT. Evaluation of the Impact of an Echocardiographic Diagnosis of Pulmonary Hypertension on Patient Outcomes. Cjc Open. 2: 328-336. PMID 32995717 DOI: 10.1016/j.cjco.2020.04.001  0.334
2020 Omura J, Habbout K, Shimauchi T, Wu WH, Breuils-Bonnet S, Tremblay E, Martineau S, Nadeau V, Gagnon K, Mazoyer F, Perron J, Potus F, Lin JH, Zafar H, Kiely DG, ... ... Archer SL, et al. Identification of The Long Non-Coding RNA H19 as a New Biomarker and Therapeutic Target in Right Ventricular Failure in Pulmonary Arterial Hypertension. Circulation. PMID 32698630 DOI: 10.1161/Circulationaha.120.047626  0.432
2020 Potus F, Martin AY, Snetsinger B, Archer SL. Biventricular Assessment of Cardiac Function and Pressure-Volume Loops by Closed-Chest Catheterization in Mice. Journal of Visualized Experiments : Jove. PMID 32597858 DOI: 10.3791/61088  0.328
2020 Archer SL, Sharp WW, Weir EK. Differentiating COVID-19 Pneumonia from Acute Respiratory Distress Syndrome (ARDS) and High Altitude Pulmonary Edema (HAPE): Therapeutic Implications. Circulation. PMID 32369390 DOI: 10.1161/Circulationaha.120.047915  0.35
2020 Tian L, Xiong PY, Alizadeh E, Lima PDA, Potus F, Mewburn J, Martin A, Chen KH, Archer SL. Supra-coronary Aortic Banding Improves Right Ventricular Function in Experimental Pulmonary Arterial Hypertension in Rats by Increasing Systolic Right Coronary Artery Perfusion. Acta Physiologica (Oxford, England). PMID 32339403 DOI: 10.1111/Apha.13483  0.436
2020 Tian L, Wu D, Dasgupta A, Chen KH, Mewburn J, Potus F, Lima PA, Hong Z, Zhao YY, Hindmarch C, Kutty S, Provencher S, Bonnet S, Sutendra G, Archer SL. Epigenetic Metabolic Reprogramming of Right Ventricular Fibroblasts in Pulmonary Arterial Hypertension: A Pyruvate Dehydrogenase Kinase-Dependent Shift in Mitochondrial Metabolism Promotes Right Ventricular Fibrosis. Circulation Research. PMID 32216531 DOI: 10.1161/Circresaha.120.316443  0.435
2020 Potus F, Pauciulo MW, Cook EK, Zhu N, Hsieh A, Welch CL, Shen Y, Tian L, Lima P, Mewburn J, D'Arsigny CL, Lutz KA, Coleman AW, Damico R, Snetsinger B, ... ... Archer SL, et al. Novel Mutations and Decreased Expression of the Epigenetic Regulator TET2 in Pulmonary Arterial Hypertension. Circulation. PMID 32192357 DOI: 10.1161/Circulationaha.119.044320  0.369
2020 Dasgupta A, Wu D, Tian L, Xiong PY, Dunham-Snary KJ, Chen KH, Alizadeh E, Motamed M, Potus F, Hindmarch CCT, Archer SL. Mitochondria in the Pulmonary Vasculature in Health and Disease: Oxygen-Sensing, Metabolism, and Dynamics. Comprehensive Physiology. 10: 713-765. PMID 32163206 DOI: 10.1002/Cphy.C190027  0.401
2020 Prins KW, Kalra R, Rose L, Assad TR, Archer SL, Bajaj NS, Weir EK, Prisco SZ, Pritzker M, Lutsey PL, Brittain EL, Thenappan T. Hypochloremia Is a Noninvasive Predictor of Mortality in Pulmonary Arterial Hypertension. Journal of the American Heart Association. 9: e015221. PMID 32079477 DOI: 10.1161/Jaha.119.015221  0.385
2020 Piao L, Fang YH, Hamanaka RB, Mutlu GM, Dezfulian C, Archer SL, Sharp WW. Suppression of Superoxide-Hydrogen Peroxide Production at Site IQ of Mitochondrial Complex I Attenuates Myocardial Stunning and Improves Postcardiac Arrest Outcomes. Critical Care Medicine. 48: e133-e140. PMID 31939812 DOI: 10.1097/Ccm.0000000000004095  0.302
2020 Vijavaraghavan M, Prins KW, Prisco SZ, John R, Voeller R, Shaffer A, Archer SL, Weir EK, Thenappan T. CHARACTERISTICS AND OUTCOMES OF PULMONARY HYPERTENSION IN PATIENTS UNDERGOING TRICUSPID VALVE REPAIR OR REPLACEMENT Journal of the American College of Cardiology. 75: 2083. DOI: 10.1016/S0735-1097(20)32710-8  0.377
2019 Dunham-Snary KJ, Archer SL. Response by Dunham-Snary and Archer to Letter Regarding Article, "Ndufs2, a Core Subunit of Mitochondrial Complex I, Is Essential for Acute Oxygen-Sensing and Hypoxic Pulmonary Vasoconstriction". Circulation Research. 125: e35-e36. PMID 31557123 DOI: 10.1161/Circresaha.119.315826  0.344
2019 Ranchoux B, Nadeau V, Bourgeois A, Provencher S, Tremblay E, Omura J, Côté N, Abu-Alhayja'a R, Dumais V, Nachbar RT, Tastet L, Dahou A, Breuils-Bonnet S, Marette A, Pibarot P, ... ... Archer SL, et al. Metabolic Syndrome Exacerbates Pulmonary Hypertension due to Left Heart Disease. Circulation Research. PMID 31154939 DOI: 10.1161/Circresaha.118.314555  0.381
2019 Dunham-Snary KJ, Wu D, Potus F, Sykes EA, Mewburn JD, Charles RL, Eaton P, Sultanian RA, Archer SL. Ndufs2, A Core Subunit of Mitochondrial Complex I, Is Essential for Acute Oxygen-Sensing and Hypoxic Pulmonary Vasoconstriction. Circulation Research. PMID 30922174 DOI: 10.1161/Circresaha.118.314284  0.434
2019 Cirulis MM, Ryan JJ, Archer S. EXPRESS: Pathophysiology, incidence, management and consequences of cardiac arrhythmia in pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension. Pulmonary Circulation. 2045894019834890. PMID 30747032 DOI: 10.1177/2045894019834890  0.48
2019 Prins KW, Rose L, Archer SL, Pritzker M, Weir EK, Olson MD, Thenappan T. Clinical Determinants and Prognostic Implications of Right Ventricular Dysfunction in Pulmonary Hypertension Caused by Chronic Lung Disease. Journal of the American Heart Association. 8: e011464. PMID 30646788 DOI: 10.1161/Jaha.118.011464  0.464
2019 Prins KW, Thenappan T, Weir EK, Kalra R, Pritzker M, Archer SL. Repurposing Medications for Treatment of Pulmonary Arterial Hypertension: What's Old Is New Again. Journal of the American Heart Association. 8: e011343. PMID 30590974 DOI: 10.1161/Jaha.118.011343  0.415
2019 Omura J, Habbout K, Martineau S, Breuils-Bonnet S, Nadeau V, Potus F, Archer SL, Paulin R, Provencher S, Boucherat O, Bonnet S. Long Non-coding RNA H19 in Right Ventricular Failure associated with Pulmonary Arterial Hypertension European Respiratory Journal. 54. DOI: 10.1183/13993003.Congress-2019.Pa5040  0.378
2019 Ranchoux B, Nadeau V, Breuils-Bonnet S, Omura J, André M, Dupuis J, Pibarot P, Paulin R, Boucherat O, Provencher S, Archer SL, Bonnet S, Potus F. Late Breaking Abstract - Inflammation and metabolic syndrome exacerbate pulmonary hypertension associated with left heart disease European Respiratory Journal. DOI: 10.1183/13993003.Congress-2019.Pa3949  0.412
2018 Xiong PY, Tian L, Dunham-Snary KJ, Chen KH, Mewburn JD, Neuber-Hess M, Martin A, Dasgupta A, Potus F, Archer SL. Biventricular Increases in Mitochondrial Fission Mediator (MiD51) and Proglycolytic Pyruvate Kinase (PKM2) Isoform in Experimental Group 2 Pulmonary Hypertension-Novel Mitochondrial Abnormalities. Frontiers in Cardiovascular Medicine. 5: 195. PMID 30740395 DOI: 10.3389/Fcvm.2018.00195  0.404
2018 Rhodes CJ, Batai K, Bleda M, Haimel M, Southgate L, Germain M, Pauciulo MW, Hadinnapola C, Aman J, Girerd B, Arora A, Knight J, Hanscombe KB, Karnes JH, Kaakinen M, ... ... Archer SL, et al. Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis. The Lancet. Respiratory Medicine. PMID 30527956 DOI: 10.1016/S2213-2600(18)30409-0  0.412
2018 Xiong PY, Baba S, Nishioka N, Fujimoto Y, Archer SL, Minamisawa S. Left Atrial Stenosis Induced Pulmonary Venous Arterialization and Group 2 Pulmonary Hypertension in Rat. Journal of Visualized Experiments : Jove. PMID 30507912 DOI: 10.3791/58787  0.455
2018 Rose L, Prins KW, Archer SL, Pritzker M, Weir EK, Misialek JR, Thenappan T. Survival in pulmonary hypertension due to chronic lung disease: Influence of low diffusion capacity of the lungs for carbon monoxide. The Journal of Heart and Lung Transplantation : the Official Publication of the International Society For Heart Transplantation. PMID 30391191 DOI: 10.1016/J.Healun.2018.09.011  0.387
2018 Potus F, Hindmarch CCT, Dunham-Snary KJ, Stafford J, Archer SL. Transcriptomic Signature of Right Ventricular Failure in Experimental Pulmonary Arterial Hypertension: Deep Sequencing Demonstrates Mitochondrial, Fibrotic, Inflammatory and Angiogenic Abnormalities. International Journal of Molecular Sciences. 19. PMID 30213070 DOI: 10.3390/Ijms19092730  0.453
2018 D'Arsigny CL, Archer SL. A Step Closer to Understanding How Riociguat Results in Remodelling of the Right Ventricle in Chronic Thromboembolic Pulmonary Hypertension. The Canadian Journal of Cardiology. 34: 1098-1101. PMID 30170664 DOI: 10.1016/J.Cjca.2018.07.008  0.442
2018 Lahm T, Douglas IS, Archer SL, Bogaard HJ, Chesler NC, Haddad F, Hemnes AR, Kawut SM, Kline JA, Kolb TM, Mathai SC, Mercier O, Michelakis ED, Naeije R, Tuder RM, et al. Assessment of Right Ventricular Function in the Research Setting: Knowledge Gaps and Pathways Forward. An Official American Thoracic Society Research Statement. American Journal of Respiratory and Critical Care Medicine. 198: e15-e43. PMID 30109950 DOI: 10.1164/Rccm.201806-1160St  0.363
2018 Tian L, Potus F, Wu D, Dasgupta A, Chen KH, Mewburn J, Lima P, Archer SL. Increased Drp1-Mediated Mitochondrial Fission Promotes Proliferation and Collagen Production by Right Ventricular Fibroblasts in Experimental Pulmonary Arterial Hypertension. Frontiers in Physiology. 9: 828. PMID 30042687 DOI: 10.3389/Fphys.2018.00828  0.392
2018 Kuebler WM, Nicolls MR, Olschewski A, Abe K, Rabinovitch M, Stewart DJ, Chan SY, Morrell NW, Archer SL, Spiekerkoetter E. A Pro - Con debate: Current Controversies in PAH Pathogenesis at the American Thoracic Society International Meeting in 2017. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 29877097 DOI: 10.1152/Ajplung.00150.2018  0.363
2018 Provencher S, Archer SL, Ramirez FD, Hibbert B, Paulin R, Boucherat O, Lacasse Y, Bonnet S. Standards and Methodological Rigor in Pulmonary Arterial Hypertension Preclinical and Translational Research. Circulation Research. 122: 1021-1032. PMID 29599278 DOI: 10.1161/Circresaha.117.312579  0.414
2018 Thenappan T, Ormiston ML, Ryan JJ, Archer SL. Pulmonary arterial hypertension: pathogenesis and clinical management. Bmj (Clinical Research Ed.). 360: j5492. PMID 29540357 DOI: 10.1136/Bmj.J5492  0.505
2018 Wijeratne DT, Lajkosz K, Brogly SB, Lougheed MD, Jiang L, Housin A, Barber D, Johnson A, Doliszny KM, Archer SL. Increasing Incidence and Prevalence of World Health Organization Groups 1 to 4 Pulmonary Hypertension: A Population-Based Cohort Study in Ontario, Canada. Circulation. Cardiovascular Quality and Outcomes. 11: e003973. PMID 29444925 DOI: 10.1161/Circoutcomes.117.003973  0.435
2018 Chen KH, Dasgupta A, Lin J, Potus F, Bonnet S, Iremonger J, Fu J, Mewburn J, Wu D, Dunham-Snary K, Theilmann AL, Jing ZC, Hindmarch C, Ormiston ML, Lawrie A, ... Archer SL, et al. Epigenetic Dysregulation of the Drp1 Binding Partners MiD49 and MiD51 Increases Mitotic Mitochondrial Fission and Promotes Pulmonary Arterial Hypertension: Mechanistic and Therapeutic Implications. Circulation. PMID 29431643 DOI: 10.1161/Circulationaha.117.031258  0.361
2018 Prins KW, Rose L, Archer SL, Pritzker M, Weir EK, Kazmirczak F, Misialek JR, Thenappan T. Disproportionate Right Ventricular Dysfunction and Poor Survival in Group 3 Pulmonary Hypertension. American Journal of Respiratory and Critical Care Medicine. PMID 29360393 DOI: 10.1164/Rccm.201712-2405Le  0.431
2018 Potus F, Hindmarch CC, Archer SL. Abstract 419: Deep Sequencing Provides Evidence Of Mitochondrial Abnormalities In Right Ventricular Failure In Pulmonary Arterial Hypertension Circulation Research. 123. DOI: 10.1161/Res.123.Suppl_1.419  0.48
2018 Dunham-Snary K, Lima P, Mewburn J, Archer S. Electron transport chain inhibitors alter membrane potential and induce mitochondrial fragmentation in vascular smooth muscle cells: implications for bioenergetic measurements Free Radical Biology and Medicine. 128: S24. DOI: 10.1016/J.Freeradbiomed.2018.10.012  0.356
2017 Archer SL. Pyruvate Kinase and Warburg Metabolism in Pulmonary Arterial Hypertension: Uncoupled Glycolysis and the Cancer-Like Phenotype of Pulmonary Arterial Hypertension. Circulation. 136: 2486-2490. PMID 29255124 DOI: 10.1161/Circulationaha.117.031655  0.465
2017 Xiong PY, Potus F, Chan W, Archer SL. Models and Molecular Mechanisms of World Health Organization Group 2 to 4 Pulmonary Hypertension. Hypertension (Dallas, Tex. : 1979). PMID 29158355 DOI: 10.1161/Hypertensionaha.117.08824  0.465
2017 Prins KW, Archer SL, Pritzker M, Rose L, Weir EK, Sharma A, Thenappan T. Interleukin-6 is independently associated with right ventricular function in pulmonary arterial hypertension. The Journal of Heart and Lung Transplantation : the Official Publication of the International Society For Heart Transplantation. PMID 28893516 DOI: 10.1016/J.Healun.2017.08.011  0.398
2017 Zhao YD, Yin L, Archer S, Lu C, Zhao G, Yao Y, Wu L, Hsin M, Waddell TK, Keshavjee S, Granton J, de Perrot M. Metabolic heterogeneity of idiopathic pulmonary fibrosis: a metabolomic study. Bmj Open Respiratory Research. 4: e000183. PMID 28883924 DOI: 10.1136/Bmjresp-2017-000183  0.402
2017 Prins KW, Tian L, Wu D, Thenappan T, Metzger JM, Archer SL. Colchicine Depolymerizes Microtubules, Increases Junctophilin-2, and Improves Right Ventricular Function in Experimental Pulmonary Arterial Hypertension. Journal of the American Heart Association. 6. PMID 28566298 DOI: 10.1161/Jaha.117.006195  0.483
2017 Tian L, Neuber-Hess M, Mewburn J, Dasgupta A, Dunham-Snary K, Wu D, Chen KH, Hong Z, Sharp WW, Kutty S, Archer SL. Ischemia-induced Drp1 and Fis1-mediated mitochondrial fission and right ventricular dysfunction in pulmonary hypertension. Journal of Molecular Medicine (Berlin, Germany). PMID 28265681 DOI: 10.1007/S00109-017-1522-8  0.424
2017 Dunham-Snary KJ, Wu D, Sykes EA, Thakrar A, Parlow LR, Mewburn JD, Parlow JL, Archer SL. Hypoxic Pulmonary Vasoconstriction: From Molecular Mechanisms to Medicine. Chest. 151: 181-192. PMID 27645688 DOI: 10.1016/J.Chest.2016.09.001  0.43
2017 Prins K, Rose L, Archer S, Sharma A, Pritzker M, Thenappan T. Right Ventricle on Fire: Interleukin-6 Is Independently Associated with Right Ventricular Function in Pulmonary Arterial Hypertension The Journal of Heart and Lung Transplantation. 36: S168. DOI: 10.1016/J.Healun.2017.01.441  0.45
2017 Dunham-Snary KJ, Wu D, Sykes EA, Potus F, Mewburn JD, Sultanian RA, Archer SL. Oxygen-sensing in the Lung is Regulated by Mitochondrial Complex I Ndufs2: Role of Mitochondria-derived Hydrogen Peroxide in Hypoxic Pulmonary Vasoconstriction Free Radical Biology and Medicine. 112: 186-187. DOI: 10.1016/J.Freeradbiomed.2017.10.291  0.407
2016 Prins KW, Weir EK, Archer SL, Markowitz J, Rose L, Pritzker M, Madlon-Kay R, Thenappan T. Pulmonary pulse wave transit time is associated with right ventricular-pulmonary artery coupling in pulmonary arterial hypertension. Pulmonary Circulation. 6: 576-585. PMID 28090301 DOI: 10.1086/688879  0.464
2016 Anand V, Roy SS, Archer SL, Weir EK, Garg SK, Duval S, Thenappan T. Trends and Outcomes of Pulmonary Arterial Hypertension-Related Hospitalizations in the United States: Analysis of the Nationwide Inpatient Sample Database From 2001 Through 2012. Jama Cardiology. PMID 27851838 DOI: 10.1001/Jamacardio.2016.3591  0.387
2016 Abman SH, Ivy DD, Archer SL, Wilson K. Executive Summary of the American Heart Association and American Thoracic Society Joint Guidelines for Pediatric Pulmonary Hypertension. American Journal of Respiratory and Critical Care Medicine. 194: 898-906. PMID 27689707 DOI: 10.1164/Rccm.201606-1183St  0.324
2016 Atkins K, Dasgupta A, Chen KH, Mewburn J, Archer SL. The role of Drp1 adaptor proteins MiD49 and MiD51 in mitochondrial fission: implications for human disease. Clinical Science (London, England : 1979). 130: 1861-74. PMID 27660309 DOI: 10.1042/Cs20160030  0.33
2016 Hong Z, Chen KH, DasGupta A, Potus F, Dunham-Snary K, Bonnet S, Tian L, Fu J, Breuils-Bonnet S, Provencher S, Wu D, Mewburn J, Ormiston ML, Archer SL. miR-138 and miR-25 Downregulate MCU, Causing Pulmonary Arterial Hypertension's Cancer Phenotype. American Journal of Respiratory and Critical Care Medicine. PMID 27648837 DOI: 10.1164/Rccm.201604-0814Oc  0.439
2016 Archer SL. Acquired Mitochondrial Abnormalities, Including Epigenetic Inhibition of Superoxide Dismutase 2, in Pulmonary Hypertension and Cancer: Therapeutic Implications. Advances in Experimental Medicine and Biology. 903: 29-53. PMID 27343087 DOI: 10.1007/978-1-4899-7678-9_3  0.398
2016 Wu D, Archer SL. Pulmonary hypertension begets pulmonary hypertension: mutually reinforcing roles for hemodynamics, inflammation and cancer-like phenotypes. Cardiovascular Research. PMID 27216865 DOI: 10.1093/Cvr/Cvw110  0.503
2016 Hemnes AR, Zhao M, West J, Newman JH, Rich S, Archer SL, Robbins IM, Blackwell TS, Cogan J, Loyd JE, Zhao Z, Gaskill C, Jetter C, Kropski JA, Majka SM, et al. Critical Genomic Networks and Vasoreactive Variants in Idiopathic Pulmonary Arterial Hypertension. American Journal of Respiratory and Critical Care Medicine. PMID 26926454 DOI: 10.1164/Rccm.201508-1678Oc  0.44
2016 Dunham-Snary KJ, Mewburn JD, Chen K, Hong ZG, Lirette AM, Xiong PY, Archer SL. Hydrogen Peroxide and Redox Control of Hypoxic Pulmonary Vasoconstriction: Identifying the Mitochondrial Redox Oxygen Sensor Free Radical Biology and Medicine. 100: S22. DOI: 10.1016/J.Freeradbiomed.2016.10.051  0.423
2015 Abman SH, Hansmann G, Archer SL, Ivy DD, Adatia I, Chung WK, Hanna BD, Rosenzweig EB, Raj JU, Cornfield D, Stenmark KR, Steinhorn R, Thébaud B, Fineman JR, Kuehne T, et al. Pediatric Pulmonary Hypertension: Guidelines From the American Heart Association and American Thoracic Society. Circulation. PMID 26534956 DOI: 10.1161/Cir.0000000000000329  0.419
2015 Dunham-Snary KJ, Hong ZG, Xiong PY, Del Paggio JC, Herr JE, Johri AM, Archer SL. A mitochondrial redox oxygen sensor in the pulmonary vasculature and ductus arteriosus. Pflugers Archiv : European Journal of Physiology. PMID 26395471 DOI: 10.1007/S00424-015-1736-Y  0.454
2015 Ryan JJ, Archer SL. Emerging concepts in the molecular basis of pulmonary arterial hypertension: part I: metabolic plasticity and mitochondrial dynamics in the pulmonary circulation and right ventricle in pulmonary arterial hypertension. Circulation. 131: 1691-702. PMID 25964279 DOI: 10.1161/Circulationaha.114.006979  0.347
2015 Ryan JJ, Huston J, Kutty S, Hatton ND, Bowman L, Tian L, Herr JE, Johri AM, Archer SL. Right ventricular adaptation and failure in pulmonary arterial hypertension. The Canadian Journal of Cardiology. 31: 391-406. PMID 25840092 DOI: 10.1016/J.Cjca.2015.01.023  0.502
2015 Ryan J, Dasgupta A, Huston J, Chen KH, Archer SL. Mitochondrial dynamics in pulmonary arterial hypertension. Journal of Molecular Medicine (Berlin, Germany). 93: 229-42. PMID 25672499 DOI: 10.1007/S00109-015-1263-5  0.466
2015 Dasgupta A, Bowman L, D'Arsigny CL, Archer SL. Soluble guanylate cyclase: a new therapeutic target for pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension. Clinical Pharmacology and Therapeutics. 97: 88-102. PMID 25670386 DOI: 10.1002/Cpt.10  0.49
2015 Hemnes AR, Trammell AW, Archer SL, Rich S, Yu C, Nian H, Penner N, Funke M, Wheeler L, Robbins IM, Austin ED, Newman JH, West J. Peripheral blood signature of vasodilator-responsive pulmonary arterial hypertension. Circulation. 131: 401-9; discussion 40. PMID 25361553 DOI: 10.1161/Circulationaha.114.013317  0.437
2015 Dunham-Snary K, Sultanian R, Hong Z, Lirette A, Xiong P, Archer S. Hydrogen Peroxide and Redox Control of HPV: Characterization of Pulmonary and Renal Artery Smooth Muscle Cell Mitochondria Free Radical Biology and Medicine. 87: S111. DOI: 10.1016/J.Freeradbiomed.2015.10.291  0.37
2014 Tuder RM, Archer SL, Dorfmüller P, Erzurum SC, Guignabert C, Michelakis E, Rabinovitch M, Schermuly R, Stenmark KR, Morrell NW. [Relevant issues in the pathology and pathobiology of pulmonary hypertension]. TüRk Kardiyoloji DerneğI ArşIvi : TüRk Kardiyoloji DerneğInin YayıN OrganıDıR. 42: 5-16. PMID 25697030  0.354
2014 Ryan JJ, Archer SL. The right ventricle in pulmonary arterial hypertension: disorders of metabolism, angiogenesis and adrenergic signaling in right ventricular failure. Circulation Research. 115: 176-88. PMID 24951766 DOI: 10.1161/Circresaha.113.301129  0.456
2014 Dweik RA, Rounds S, Erzurum SC, Archer S, Fagan K, Hassoun PM, Hill NS, Humbert M, Kawut SM, Krowka M, Michelakis E, Morrell NW, Stenmark K, Tuder RM, Newman J, et al. An official American Thoracic Society Statement: pulmonary hypertension phenotypes. American Journal of Respiratory and Critical Care Medicine. 189: 345-55. PMID 24484330 DOI: 10.1164/Rccm.201311-1954St  0.329
2014 Sharp WW, Fang YH, Han M, Zhang HJ, Hong Z, Banathy A, Morrow E, Ryan JJ, Archer SL. Dynamin-related protein 1 (Drp1)-mediated diastolic dysfunction in myocardial ischemia-reperfusion injury: therapeutic benefits of Drp1 inhibition to reduce mitochondrial fission. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 316-26. PMID 24076965 DOI: 10.1096/Fj.12-226225  0.306
2013 Tuder RM, Archer SL, Dorfmüller P, Erzurum SC, Guignabert C, Michelakis E, Rabinovitch M, Schermuly R, Stenmark KR, Morrell NW. Relevant issues in the pathology and pathobiology of pulmonary hypertension. Journal of the American College of Cardiology. 62: D4-12. PMID 24355640 DOI: 10.1016/J.Jacc.2013.10.025  0.458
2013 Ryan JJ, Marsboom G, Archer SL. Rodent models of group 1 pulmonary hypertension. Handbook of Experimental Pharmacology. 218: 105-49. PMID 24092338 DOI: 10.1007/978-3-642-38664-0_5  0.461
2013 von Gise A, Archer SL, Maclean MR, Hansmann G. The first Keystone Symposia Conference on pulmonary vascular isease and right ventricular dysfunction: Current concepts and future therapies. Pulmonary Circulation. 3: 275-7. PMID 24015328 DOI: 10.4103/2045-8932.114751  0.404
2013 Archer SL. Riociguat for pulmonary hypertension--a glass half full. The New England Journal of Medicine. 369: 386-8. PMID 23883383 DOI: 10.1056/Nejme1306684  0.474
2013 Piao L, Fang YH, Parikh K, Ryan JJ, Toth PT, Archer SL. Cardiac glutaminolysis: a maladaptive cancer metabolism pathway in the right ventricle in pulmonary hypertension. Journal of Molecular Medicine (Berlin, Germany). 91: 1185-97. PMID 23794090 DOI: 10.1007/S00109-013-1064-7  0.439
2013 Morrell NW, Archer SL, Defelice A, Evans S, Fiszman M, Martin T, Saulnier M, Rabinovitch M, Schermuly R, Stewart D, Truebel H, Walker G, Stenmark KR. Anticipated classes of new medications and molecular targets for pulmonary arterial hypertension. Pulmonary Circulation. 3: 226-44. PMID 23662201 DOI: 10.4103/2045-8932.109940  0.375
2013 Archer SL, Fang YH, Ryan JJ, Piao L. Metabolism and bioenergetics in the right ventricle and pulmonary vasculature in pulmonary hypertension. Pulmonary Circulation. 3: 144-52. PMID 23662191 DOI: 10.4103/2045-8932.109960  0.478
2013 Ryan JJ, Marsboom G, Fang YH, Toth PT, Morrow E, Luo N, Piao L, Hong Z, Ericson K, Zhang HJ, Han M, Haney CR, Chen CT, Sharp WW, Archer SL. PGC1α-mediated mitofusin-2 deficiency in female rats and humans with pulmonary arterial hypertension. American Journal of Respiratory and Critical Care Medicine. 187: 865-78. PMID 23449689 DOI: 10.1164/Rccm.201209-1687Oc  0.479
2013 Hong Z, Kutty S, Toth PT, Marsboom G, Hammel JM, Chamberlain C, Ryan JJ, Zhang HJ, Sharp WW, Morrow E, Trivedi K, Weir EK, Archer SL. Role of dynamin-related protein 1 (Drp1)-mediated mitochondrial fission in oxygen sensing and constriction of the ductus arteriosus. Circulation Research. 112: 802-15. PMID 23334860 DOI: 10.1161/Circresaha.111.300285  0.34
2013 Piao L, Sidhu VK, Fang YH, Ryan JJ, Parikh KS, Hong Z, Toth PT, Morrow E, Kutty S, Lopaschuk GD, Archer SL. FOXO1-mediated upregulation of pyruvate dehydrogenase kinase-4 (PDK4) decreases glucose oxidation and impairs right ventricular function in pulmonary hypertension: therapeutic benefits of dichloroacetate. Journal of Molecular Medicine (Berlin, Germany). 91: 333-46. PMID 23247844 DOI: 10.1007/S00109-012-0982-0  0.408
2013 Rich JD, Archer SL, Rich S. Noninvasive cardiac output measurements in patients with pulmonary hypertension. The European Respiratory Journal. 42: 125-33. PMID 23100501 DOI: 10.1183/09031936.00102212  0.329
2013 Rich JD, Thenappan T, Freed B, Patel AR, Thisted RA, Childers R, Archer SL. QTc prolongation is associated with impaired right ventricular function and predicts mortality in pulmonary hypertension. International Journal of Cardiology. 167: 669-76. PMID 22459397 DOI: 10.1016/J.Ijcard.2012.03.071  0.411
2013 Ryan J, Marsboom G, Hu Fang Y, Toth P, Morrow E, Luo N, Hong Z, Ericson K, Zhang H, Haney C, Chen C, Sharp W, Archer S. PGClα-MEDIATED MITOFUSIN-2 DEFICIENCY IN PULMONARY ARTERIAL HYPERTENSION CAN BE REGRESSED BY PRO-FUSION AND ANTI-FISSION THERAPY Journal of the American College of Cardiology. 61: E1295. DOI: 10.1016/S0735-1097(13)61295-4  0.493
2012 Piao L, Fang YH, Parikh KS, Ryan JJ, D'Souza KM, Theccanat T, Toth PT, Pogoriler J, Paul J, Blaxall BC, Akhter SA, Archer SL. GRK2-mediated inhibition of adrenergic and dopaminergic signaling in right ventricular hypertrophy: therapeutic implications in pulmonary hypertension. Circulation. 126: 2859-69. PMID 23124027 DOI: 10.1161/Circulationaha.112.109868  0.334
2012 Thenappan T, Ryan JJ, Archer SL. Evolving epidemiology of pulmonary arterial hypertension. American Journal of Respiratory and Critical Care Medicine. 186: 707-9. PMID 23071187 DOI: 10.1164/Rccm.201207-1266Ed  0.432
2012 Pogoriler JE, Rich S, Archer SL, Husain AN. Persistence of complex vascular lesions despite prolonged prostacyclin therapy of pulmonary arterial hypertension. Histopathology. 61: 597-609. PMID 22748137 DOI: 10.1111/J.1365-2559.2012.04246.X  0.464
2012 Ryan JJ, Thenappan T, Luo N, Ha T, Patel AR, Rich S, Archer SL. The WHO classification of pulmonary hypertension: A case-based imaging compendium. Pulmonary Circulation. 2: 107-21. PMID 22558526 DOI: 10.4103/2045-8932.94843  0.374
2012 Marsboom G, Toth PT, Ryan JJ, Hong Z, Wu X, Fang YH, Thenappan T, Piao L, Zhang HJ, Pogoriler J, Chen Y, Morrow E, Weir EK, Rehman J, Archer SL. Dynamin-related protein 1-mediated mitochondrial mitotic fission permits hyperproliferation of vascular smooth muscle cells and offers a novel therapeutic target in pulmonary hypertension. Circulation Research. 110: 1484-97. PMID 22511751 DOI: 10.1161/Circresaha.111.263848  0.671
2012 Rehman J, Zhang HJ, Toth PT, Zhang Y, Marsboom G, Hong Z, Salgia R, Husain AN, Wietholt C, Archer SL. Inhibition of mitochondrial fission prevents cell cycle progression in lung cancer. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 2175-86. PMID 22321727 DOI: 10.1096/Fj.11-196543  0.568
2012 Freed BH, Gomberg-Maitland M, Chandra S, Mor-Avi V, Rich S, Archer SL, Jamison EB, Lang RM, Patel AR. Late gadolinium enhancement cardiovascular magnetic resonance predicts clinical worsening in patients with pulmonary hypertension. Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society For Cardiovascular Magnetic Resonance. 14: 11. PMID 22296860 DOI: 10.1186/1532-429X-14-11  0.381
2012 Marsboom G, Wietholt C, Haney CR, Toth PT, Ryan JJ, Morrow E, Thenappan T, Bache-Wiig P, Piao L, Paul J, Chen CT, Archer SL. Lung ¹⁸F-fluorodeoxyglucose positron emission tomography for diagnosis and monitoring of pulmonary arterial hypertension. American Journal of Respiratory and Critical Care Medicine. 185: 670-9. PMID 22246173 DOI: 10.1164/Rccm.201108-1562Oc  0.383
2012 Fang YH, Piao L, Hong Z, Toth PT, Marsboom G, Bache-Wiig P, Rehman J, Archer SL. Therapeutic inhibition of fatty acid oxidation in right ventricular hypertrophy: exploiting Randle's cycle. Journal of Molecular Medicine (Berlin, Germany). 90: 31-43. PMID 21874543 DOI: 10.1007/S00109-011-0804-9  0.639
2012 Piao L, Sidhu VK, Fang Y, Thenappan T, Lopaschuk G, Archer S. CHRONIC INHIBITION OF PYRUVATE DEHYDROGENASE KINASE WITH DICHLOROACETATE, IMPROVES CARDIAC METABOLISM AND FUNCTION IN RIGHT VENTRICULAR HYPERTROPHY IN FAWN-HOODED RATS Journal of the American College of Cardiology. 59: E1604. DOI: 10.1016/S0735-1097(12)61605-2  0.326
2011 Kim GH, Ryan JJ, Marsboom G, Archer SL. Epigenetic mechanisms of pulmonary hypertension. Pulmonary Circulation. 1: 347-56. PMID 22140624 DOI: 10.4103/2045-8932.87300  0.344
2011 Ryan JJ, Rich S, Archer SL. Pulmonary endarterectomy surgery--a technically demanding cure for WHO Group IV Pulmonary Hypertension: requirements for centres of excellence and availability in Canada. The Canadian Journal of Cardiology. 27: 671-4. PMID 22019277 DOI: 10.1016/J.Cjca.2011.09.013  0.446
2011 Ryan JJ, Rehman J, Archer SL. Paracrine proliferative signaling by senescent cells in world health organization group 3 pulmonary hypertension: age corrupting youth? Circulation Research. 109: 476-9. PMID 21852552 DOI: 10.1161/Circresaha.111.251579  0.637
2011 Ryan J, Bloch K, Archer SL. Rodent models of pulmonary hypertension: harmonisation with the world health organisation's categorisation of human PH. International Journal of Clinical Practice. Supplement. 15-34. PMID 21736677 DOI: 10.1111/J.1742-1241.2011.02710.X  0.336
2011 Luong C, Rey-Perra J, Vadivel A, Gilmour G, Sauve Y, Koonen D, Walker D, Todd KG, Gressens P, Kassiri Z, Nadeem K, Morgan B, Eaton F, Dyck JR, Archer SL, et al. Antenatal sildenafil treatment attenuates pulmonary hypertension in experimental congenital diaphragmatic hernia. Circulation. 123: 2120-31. PMID 21537000 DOI: 10.1161/Circulationaha.108.845909  0.488
2011 Jaff MR, McMurtry MS, Archer SL, Cushman M, Goldenberg N, Goldhaber SZ, Jenkins JS, Kline JA, Michaels AD, Thistlethwaite P, Vedantham S, White RJ, Zierler BK, et al. Management of massive and submassive pulmonary embolism, iliofemoral deep vein thrombosis, and chronic thromboembolic pulmonary hypertension: a scientific statement from the American Heart Association. Circulation. 123: 1788-830. PMID 21422387 DOI: 10.1161/Cir.0B013E318214914F  0.368
2011 Thenappan T, Goel A, Marsboom G, Fang YH, Toth PT, Zhang HJ, Kajimoto H, Hong Z, Paul J, Wietholt C, Pogoriler J, Piao L, Rehman J, Archer SL. A central role for CD68(+) macrophages in hepatopulmonary syndrome. Reversal by macrophage depletion. American Journal of Respiratory and Critical Care Medicine. 183: 1080-91. PMID 21148721 DOI: 10.1164/Rccm.201008-1303Oc  0.538
2011 Weir EK, Wagner WW, Archer SL. Lofty Goals at High Altitude: The Grover Conferences, 1984–2011 Pulmonary Circulation. 1: 501-507. DOI: 10.4103/2045-8932.93550  0.487
2011 Freed BH, Gomberg-Maitland M, Chandra S, Rich S, Jamison E, Archer S, Lang RM, Patel AR. LATE GADOLINIUM ENHANCEMENT OF THE RIGHT VENTRICULAR INSERTION POINT PREDICTS SURVIVAL IN PATIENTS WITH PULMONARY HYPERTENSION Journal of the American College of Cardiology. 57: E889. DOI: 10.1016/S0735-1097(11)60889-9  0.408
2010 Rich S, Pogoriler J, Husain AN, Toth PT, Gomberg-Maitland M, Archer SL. Long-term effects of epoprostenol on the pulmonary vasculature in idiopathic pulmonary arterial hypertension. Chest. 138: 1234-9. PMID 21051399 DOI: 10.1378/Chest.09-2815  0.492
2010 Erzurum S, Rounds SI, Stevens T, Aldred M, Aliotta J, Archer SL, Asosingh K, Balaban R, Bauer N, Bhattacharya J, Bogaard H, Choudhary G, Dorn GW, Dweik R, Fagan K, et al. Strategic plan for lung vascular research: An NHLBI-ORDR Workshop Report. American Journal of Respiratory and Critical Care Medicine. 182: 1554-62. PMID 20833821 DOI: 10.1164/Rccm.201006-0869Ws  0.362
2010 Piao L, Marsboom G, Archer SL. Mitochondrial metabolic adaptation in right ventricular hypertrophy and failure. Journal of Molecular Medicine (Berlin, Germany). 88: 1011-20. PMID 20820751 DOI: 10.1007/S00109-010-0679-1  0.448
2010 Weir EK, Archer SL. The role of redox changes in oxygen sensing. Respiratory Physiology & Neurobiology. 174: 182-91. PMID 20801237 DOI: 10.1016/J.Resp.2010.08.015  0.365
2010 Urboniene D, Haber I, Fang YH, Thenappan T, Archer SL. Validation of high-resolution echocardiography and magnetic resonance imaging vs. high-fidelity catheterization in experimental pulmonary hypertension. American Journal of Physiology. Lung Cellular and Molecular Physiology. 299: L401-12. PMID 20581101 DOI: 10.1152/Ajplung.00114.2010  0.403
2010 Archer SL, Marsboom G, Kim GH, Zhang HJ, Toth PT, Svensson EC, Dyck JR, Gomberg-Maitland M, Thébaud B, Husain AN, Cipriani N, Rehman J. Epigenetic attenuation of mitochondrial superoxide dismutase 2 in pulmonary arterial hypertension: a basis for excessive cell proliferation and a new therapeutic target. Circulation. 121: 2661-71. PMID 20529999 DOI: 10.1161/Circulationaha.109.916098  0.685
2010 Archer SL, Weir EK, Wilkins MR. Basic science of pulmonary arterial hypertension for clinicians: new concepts and experimental therapies. Circulation. 121: 2045-66. PMID 20458021 DOI: 10.1161/Circulationaha.108.847707  0.477
2010 Sweiss NJ, Hushaw L, Thenappan T, Sawaqed R, Machado RF, Patel AR, Gomberg-Maitland M, Husain AN, Archer SL. Diagnosis and management of pulmonary hypertension in systemic sclerosis. Current Rheumatology Reports. 12: 8-18. PMID 20425528 DOI: 10.1007/S11926-009-0078-1  0.49
2010 Rehman J, Archer SL. A proposed mitochondrial-metabolic mechanism for initiation and maintenance of pulmonary arterial hypertension in fawn-hooded rats: the Warburg model of pulmonary arterial hypertension. Advances in Experimental Medicine and Biology. 661: 171-85. PMID 20204730 DOI: 10.1007/978-1-60761-500-2_11  0.685
2010 Thenappan T, Shah SJ, Rich S, Tian L, Archer SL, Gomberg-Maitland M. Survival in pulmonary arterial hypertension: A reappraisal of the NIH risk stratification equation European Respiratory Journal. 35: 1079-1087. PMID 20032020 DOI: 10.1183/09031936.00072709  0.316
2010 Piao L, Fang YH, Cadete VJ, Wietholt C, Urboniene D, Toth PT, Marsboom G, Zhang HJ, Haber I, Rehman J, Lopaschuk GD, Archer SL. The inhibition of pyruvate dehydrogenase kinase improves impaired cardiac function and electrical remodeling in two models of right ventricular hypertrophy: resuscitating the hibernating right ventricle. Journal of Molecular Medicine (Berlin, Germany). 88: 47-60. PMID 19949938 DOI: 10.1007/S00109-009-0524-6  0.656
2010 Chandra S, Shah SJ, Thenappan T, Archer SL, Rich S, Gomberg-Maitland M. Carbon monoxide diffusing capacity and mortality in pulmonary arterial hypertension Journal of Heart and Lung Transplantation. 29: 181-187. PMID 19783169 DOI: 10.1016/J.Healun.2009.07.005  0.411
2010 Freed B, Gomberg-Maitland M, Chandra S, Rich S, Jamison E, Archer S, Patel A. 437: CMR Late Gadolinium Enhancement of the Right Ventricular Insertion Point in Pulmonary Arterial Hypertension The Journal of Heart and Lung Transplantation. 29: S144-S145. DOI: 10.1016/J.Healun.2009.11.452  0.466
2009 Gomberg-Maitland M, Maitland ML, Barst RJ, Sugeng L, Coslet S, Perrino TJ, Bond L, Lacouture ME, Archer SL, Ratain MJ. A dosing/cross-development study of the multikinase inhibitor sorafenib in patients with pulmonary arterial hypertension. Clinical Pharmacology and Therapeutics. 87: 303-10. PMID 20010555 DOI: 10.1038/Clpt.2009.217  0.352
2009 Archer SL, Michelakis ED. Phosphodiesterase type 5 inhibitors for pulmonary arterial hypertension. The New England Journal of Medicine. 361: 1864-71. PMID 19890129 DOI: 10.1056/Nejmct0904473  0.478
2009 Shah SJ, Thenappan T, Rich S, Sur J, Archer SL, Gomberg-Maitland M. Value of exercise treadmill testing in the risk stratification of patients with pulmonary hypertension Circulation: Heart Failure. 2: 278-286. PMID 19808350 DOI: 10.1161/Circheartfailure.108.807826  0.358
2009 Morrell NW, Adnot S, Archer SL, Dupuis J, Jones PL, MacLean MR, McMurtry IF, Stenmark KR, Thistlethwaite PA, Weissmann N, Yuan JX, Weir EK. Cellular and molecular basis of pulmonary arterial hypertension. Journal of the American College of Cardiology. 54: S20-31. PMID 19555855 DOI: 10.1016/J.Jacc.2009.04.018  0.452
2009 Polonsky TS, Taillon LA, Sheth H, Min JK, Archer SL, Ward RP. The association between erectile dysfunction and peripheral arterial disease as determined by screening ankle-brachial index testing. Atherosclerosis. 207: 440-4. PMID 19501825 DOI: 10.1016/J.Atherosclerosis.2009.05.005  0.324
2009 McLaughlin VV, Archer SL, Badesch DB, Barst RJ, Farber HW, Lindner JR, Mathier MA, McGoon MD, Park MH, Rosenson RS, Rubin LJ, Tapson VF, Varga J, et al. ACCF/AHA 2009 expert consensus document on pulmonary hypertension a report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents and the American Heart Association developed in collaboration with the American College of Chest Physicians; American Thoracic Society, Inc.; and the Pulmonary Hypertension Association. Journal of the American College of Cardiology. 53: 1573-619. PMID 19389575 DOI: 10.1016/J.Jacc.2009.01.004  0.342
2009 McLaughlin VV, Archer SL, Badesch DB, Barst RJ, Farber HW, Lindner JR, Mathier MA, McGoon MD, Park MH, Rosenson RS, Rubin LJ, Tapson VF, Varga J, Harrington RA, Anderson JL, et al. ACCF/AHA 2009 expert consensus document on pulmonary hypertension: a report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents and the American Heart Association: developed in collaboration with the American College of Chest Physicians, American Thoracic Society, Inc., and the Pulmonary Hypertension Association. Circulation. 119: 2250-94. PMID 19332472 DOI: 10.1161/Circulationaha.109.192230  0.322
2009 Zhang H, Kim G, Toth P, Marsboon G, Urboniene D, Svensson E, Rehman J, Archer S. 227: The Demethylating Agent 5-aza-2'Deoxycytidine (Decitabine) Reverses SOD2 Methylation and Restores H2O2 Production in the Pulmonary Arterial Smooth Muscle Cells of Fawn-Hooded Rats with Pulmonary Hypertension The Journal of Heart and Lung Transplantation. 28: S145-S146. DOI: 10.1016/J.Healun.2008.11.857  0.662
2009 Toth P, Zhang H, Rehman J, Zhang Y, Archer S. 710: HIF-1α Activation by Cobalt Hyperpolarizes and Fragments Mitochondria in Pulmonary Artery Smooth Muscle Cells Creating a “Pulmonary Arterial Hypertension” Phenotype as Seen in Fawn-Hooded Rats The Journal of Heart and Lung Transplantation. 28: S312-S313. DOI: 10.1016/J.Healun.2008.11.717  0.641
2008 Marsboom G, Archer SL. Pathways of proliferation: new targets to inhibit the growth of vascular smooth muscle cells. Circulation Research. 103: 1047-9. PMID 18988899 DOI: 10.1161/Circresaha.108.188003  0.353
2008 Rey-Parra GJ, Archer SL, Bland RD, Albertine KH, Carlton DP, Cho SC, Kirby B, Haromy A, Eaton F, Wu X, Thébaud B. Blunted hypoxic pulmonary vasoconstriction in experimental neonatal chronic lung disease. American Journal of Respiratory and Critical Care Medicine. 178: 399-406. PMID 18511704 DOI: 10.1164/Rccm.200711-1631Oc  0.387
2008 Shah SJ, Thenappan T, Rich S, Tian L, Archer SL, Gomberg-Maitland M. Association of serum creatinine with abnormal hemodynamics and mortality in pulmonary arterial hypertension Circulation. 117: 2475-2483. PMID 18458173 DOI: 10.1161/Circulationaha.107.719500  0.363
2008 Archer SL, Gomberg-Maitland M, Maitland ML, Rich S, Garcia JG, Weir EK. Mitochondrial metabolism, redox signaling, and fusion: a mitochondria-ROS-HIF-1alpha-Kv1.5 O2-sensing pathway at the intersection of pulmonary hypertension and cancer. American Journal of Physiology. Heart and Circulatory Physiology. 294: H570-8. PMID 18083891 DOI: 10.1152/Ajpheart.01324.2007  0.406
2007 McMurtry MS, Bonnet S, Michelakis ED, Bonnet S, Haromy A, Archer SL. Statin therapy, alone or with rapamycin, does not reverse monocrotaline pulmonary arterial hypertension: the rapamcyin-atorvastatin-simvastatin study. American Journal of Physiology. Lung Cellular and Molecular Physiology. 293: L933-40. PMID 17675370 DOI: 10.1152/Ajplung.00310.2006  0.457
2007 Nagendran J, Archer SL, Soliman D, Gurtu V, Moudgil R, Haromy A, St Aubin C, Webster L, Rebeyka IM, Ross DB, Light PE, Dyck JR, Michelakis ED. Phosphodiesterase type 5 is highly expressed in the hypertrophied human right ventricle, and acute inhibition of phosphodiesterase type 5 improves contractility. Circulation. 116: 238-48. PMID 17606845 DOI: 10.1161/Circulationaha.106.655266  0.474
2007 Bonnet S, Rochefort G, Sutendra G, Archer SL, Haromy A, Webster L, Hashimoto K, Bonnet SN, Michelakis ED. The nuclear factor of activated T cells in pulmonary arterial hypertension can be therapeutically targeted. Proceedings of the National Academy of Sciences of the United States of America. 104: 11418-23. PMID 17596340 DOI: 10.1073/Pnas.0610467104  0.451
2007 Bonnet S, Archer SL. Potassium channel diversity in the pulmonary arteries and pulmonary veins: implications for regulation of the pulmonary vasculature in health and during pulmonary hypertension. Pharmacology & Therapeutics. 115: 56-69. PMID 17583356 DOI: 10.1016/J.Pharmthera.2007.03.014  0.434
2007 Kajimoto H, Hashimoto K, Bonnet SN, Haromy A, Harry G, Moudgil R, Nakanishi T, Rebeyka I, Thébaud B, Michelakis ED, Archer SL. Oxygen activates the rho/rho-kinase pathway and induces RhoB and ROCK-1 expression in human and rabbit ductus arteriosus by increasing mitochondria-derived reactive oxygen species: A newly recognized mechanism for sustaining ductal constriction Circulation. 115: 1777-1788. PMID 17353442 DOI: 10.1161/Circulationaha.106.649566  0.33
2007 Bonnet S, Archer SL, Allalunis-Turner J, Haromy A, Beaulieu C, Thompson R, Lee CT, Lopaschuk GD, Puttagunta L, Bonnet S, Harry G, Hashimoto K, Porter CJ, Andrade MA, Thebaud B, et al. A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth. Cancer Cell. 11: 37-51. PMID 17222789 DOI: 10.1016/J.Ccr.2006.10.020  0.302
2007 McMurtry MS, Moudgil R, Hashimoto K, Bonnet S, Michelakis ED, Archer SL. Overexpression of human bone morphogenetic protein receptor 2 does not ameliorate monocrotaline pulmonary arterial hypertension. American Journal of Physiology. Lung Cellular and Molecular Physiology. 292: L872-8. PMID 17142350 DOI: 10.1152/Ajplung.00309.2006  0.423
2007 Thenappan T, Shah SJ, Rich S, Archer SL, Gomberg-Maitland M. SURVIVAL OF PATIENTS WITH PULMONARY ARTERIAL HYPERTENSION (PAH) IN THE CURRENT ERA: VALIDATION OF THE NATIONAL INSTITUTE OF HEALTH (NIH) RISK STRATIFICATION EQUATION Chest. 132: 487A. DOI: 10.1378/Chest.132.4_Meetingabstracts.487A  0.394
2006 Moudgil R, Michelakis ED, Archer SL. The role of k+ channels in determining pulmonary vascular tone, oxygen sensing, cell proliferation, and apoptosis: implications in hypoxic pulmonary vasoconstriction and pulmonary arterial hypertension. Microcirculation (New York, N.Y. : 1994). 13: 615-32. PMID 17085423 DOI: 10.1080/10739680600930222  0.443
2006 Weir EK, Archer SL. Counterpoint: Hypoxic pulmonary vasoconstriction is not mediated by increased production of reactive oxygen species. Journal of Applied Physiology (Bethesda, Md. : 1985). 101: 995-8; discussion 99. PMID 16902070 DOI: 10.1152/Japplphysiol.00480A.2006  0.405
2006 Archer SL, Michelakis ED. An evidence-based approach to the management of pulmonary arterial hypertension. Current Opinion in Cardiology. 21: 385-92. PMID 16755209 DOI: 10.1097/01.Hco.0000231410.07426.9B  0.453
2006 Bonnet S, Michelakis ED, Porter CJ, Andrade-Navarro MA, Thébaud B, Bonnet S, Haromy A, Harry G, Moudgil R, McMurtry MS, Weir EK, Archer SL. An abnormal mitochondrial-hypoxia inducible factor-1alpha-Kv channel pathway disrupts oxygen sensing and triggers pulmonary arterial hypertension in fawn hooded rats: similarities to human pulmonary arterial hypertension. Circulation. 113: 2630-41. PMID 16735674 DOI: 10.1161/Circulationaha.105.609008  0.492
2006 Archer SL, Michelakis ED, Thébaud B, Bonnet S, Moudgil R, Wu XC, Weir EK. A central role for oxygen-sensitive K+ channels and mitochondria in the specialized oxygen-sensing system. Novartis Foundation Symposium. 272: 157-71; discussion 1. PMID 16686435 DOI: 10.1002/9780470035009.Ch13  0.411
2006 Nagendran J, Stewart K, Hoskinson M, Archer SL. An anesthesiologist's guide to hypoxic pulmonary vasoconstriction: implications for managing single-lung anesthesia and atelectasis. Current Opinion in Anaesthesiology. 19: 34-43. PMID 16547431 DOI: 10.1097/01.Aco.0000192777.09527.9E  0.432
2006 Weir EK, Archer SL. Last Word: Point:Counterpoint authors respond to commentaries on “Hypoxic pulmonary vasoconstriction is/is not mediated by increased production of reactive oxygen species” Journal of Applied Physiology. 101: 1005-1005. DOI: 10.1152/Japplphysiol.00707.2006  0.314
2005 Langleben D, Archer S, Granton J, Hirsch AM, Levy RD, Mehta S, Michelakis E, Stewart DJ. Canadian Cardiovascular Society and Canadian Thoracic Society position statement on pulmonary arterial hypertension. Canadian Respiratory Journal : Journal of the Canadian Thoracic Society. 12: 303-15. PMID 16247528 DOI: 10.1155/2005/156750  0.44
2005 Archer SL, Gragasin FS, Webster L, Bochinski D, Michelakis ED. Aetiology and management of male erectile dysfunction and female sexual dysfunction in patients with cardiovascular disease. Drugs & Aging. 22: 823-44. PMID 16245957 DOI: 10.2165/00002512-200522100-00003  0.347
2005 Langleben D, Archer S, Granton J, Hirsch AM, Levy RD, Mehta S, Michelakis E, Stewart DJ. Canadian Cardiovascular Society and Canadian Thoracic Society position statement on pulmonary arterial hypertension. The Canadian Journal of Cardiology. 21: 909-14. PMID 16239973  0.331
2005 Thébaud B, Ladha F, Michelakis ED, Sawicka M, Thurston G, Eaton F, Hashimoto K, Harry G, Haromy A, Korbutt G, Archer SL. Vascular endothelial growth factor gene therapy increases survival, promotes lung angiogenesis, and prevents alveolar damage in hyperoxia-induced lung injury: evidence that angiogenesis participates in alveolarization. Circulation. 112: 2477-86. PMID 16230500 DOI: 10.1161/Circulationaha.105.541524  0.32
2005 Hong Z, Smith AJ, Archer SL, Wu XC, Nelson DP, Peterson D, Johnson G, Weir EK. Pergolide is an inhibitor of voltage-gated potassium channels, including Kv1.5, and causes pulmonary vasoconstriction. Circulation. 112: 1494-9. PMID 16129789 DOI: 10.1161/Circulationaha.105.556704  0.47
2005 Archer SL. Pre-B-cell colony-enhancing factor regulates vascular smooth muscle maturation through a NAD+-dependent mechanism: recognition of a new mechanism for cell diversity and redox regulation of vascular tone and remodeling. Circulation Research. 97: 4-7. PMID 16002754 DOI: 10.1161/01.Res.0000174111.52307.64  0.404
2005 McMurtry MS, Archer SL, Altieri DC, Bonnet S, Haromy A, Harry G, Bonnet S, Puttagunta L, Michelakis ED. Gene therapy targeting survivin selectively induces pulmonary vascular apoptosis and reverses pulmonary arterial hypertension. The Journal of Clinical Investigation. 115: 1479-91. PMID 15931388 DOI: 10.1172/Jci23203  0.471
2005 Moudgil R, Michelakis ED, Archer SL. Hypoxic pulmonary vasoconstriction. Journal of Applied Physiology (Bethesda, Md. : 1985). 98: 390-403. PMID 15591309 DOI: 10.1152/Japplphysiol.00733.2004  0.426
2005 Michelakis ED, Thébaud B, Weir EK, Archer SL. Hypoxic pulmonary vasoconstriction: redox regulation of O2-sensitive K+ channels by a mitochondrial O2-sensor in resistance artery smooth muscle cells. Journal of Molecular and Cellular Cardiology. 37: 1119-36. PMID 15572043 DOI: 10.1016/J.Yjmcc.2004.09.007  0.412
2005 Gragasin FS, Michelakis ED, Hogan A, Moudgil R, Hashimoto K, Wu X, Bonnet S, Haromy A, Archer SL. The neurovascular mechanism of clitoral erection: nitric oxide and cGMP-stimulated activation of BKCa channels. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 1382-91. PMID 15333581 DOI: 10.1096/Fj.04-1978Com  0.301
2004 Archer SL, Wu XC, Thébaud B, Nsair A, Bonnet S, Tyrrell B, McMurtry MS, Hashimoto K, Harry G, Michelakis ED. Preferential expression and function of voltage-gated, O2-sensitive K+ channels in resistance pulmonary arteries explains regional heterogeneity in hypoxic pulmonary vasoconstriction: ionic diversity in smooth muscle cells. Circulation Research. 95: 308-18. PMID 15217912 DOI: 10.1161/01.Res.0000137173.42723.Fb  0.379
2004 Newman JH, Fanburg BL, Archer SL, Badesch DB, Barst RJ, Garcia JG, Kao PN, Knowles JA, Loyd JE, McGoon MD, Morse JH, Nichols WC, Rabinovitch M, Rodman DM, Stevens T, et al. Pulmonary arterial hypertension: future directions: report of a National Heart, Lung and Blood Institute/Office of Rare Diseases workshop. Circulation. 109: 2947-52. PMID 15210611 DOI: 10.1161/01.Cir.0000132476.87231.6F  0.445
2004 Humbert M, Morrell NW, Archer SL, Stenmark KR, MacLean MR, Lang IM, Christman BW, Weir EK, Eickelberg O, Voelkel NF, Rabinovitch M. Cellular and molecular pathobiology of pulmonary arterial hypertension. Journal of the American College of Cardiology. 43: 13S-24S. PMID 15194174 DOI: 10.1016/J.Jacc.2004.02.029  0.491
2004 Archer SL, Wu XC, Thébaud B, Moudgil R, Hashimoto K, Michelakis ED. O2 sensing in the human ductus arteriosus: redox-sensitive K+ channels are regulated by mitochondria-derived hydrogen peroxide. Biological Chemistry. 385: 205-16. PMID 15134333 DOI: 10.1515/Bc.2004.014  0.355
2003 Michelakis ED, McMurtry MS, Sonnenberg B, Archer SL. The NO - K+ channel axis in pulmonary arterial hypertension: Activation by experimental oral therapies Advances in Experimental Medicine and Biology. 543: 293-322. PMID 14713130 DOI: 10.1007/978-1-4419-8997-0_21  0.468
2003 Michelakis ED, Tymchak W, Noga M, Webster L, Wu XC, Lien D, Wang SH, Modry D, Archer SL. Long-term treatment with oral sildenafil is safe and improves functional capacity and hemodynamics in patients with pulmonary arterial hypertension. Circulation. 108: 2066-9. PMID 14568893 DOI: 10.1161/01.Cir.0000099502.17776.C2  0.436
2003 Lara N, Chrapko WE, Archer SL, Bellavance F, Mayers I, Le Mellédo JM. Pulmonary and systemic nitric oxide measurements during CCK-5-induced panic attacks. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 1840-5. PMID 12865901 DOI: 10.1038/Sj.Npp.1300241  0.398
2003 Pozeg ZI, Michelakis ED, McMurtry S, Thébaud B, Wu XC, Dyck JRB, Hashimoto K, Wang S, Moudgil R, Harry G, Sultanian R, Koshal A, Archer SL. In vivo gene transfer of the O2-sensitive potassium channel Kv1.5 reduces pulmonary hypertension and restores hypoxic pulmonary vasoconstriction in chronically hypoxic rats Circulation. 107: 2037-2044. PMID 12695303 DOI: 10.1161/01.Cir.0000062688.76508.B3  0.422
2003 Archer SL, Gragasin FS, Wu X, Wang S, McMurtry S, Kim DH, Platonov M, Koshal A, Hashimoto K, Campbell WB, Falck JR, Michelakis ED. Endothelium-derived hyperpolarizing factor in human internal mammary artery is 11,12-epoxyeicosatrienoic acid and causes relaxation by activating smooth muscle BKCa channels Circulation. 107: 769-776. PMID 12578883 DOI: 10.1161/01.Cir.0000047278.28407.C2  0.34
2003 Archer SL. Potassium channels and erectile dysfunction. Vascular Pharmacology. 38: 61-71. PMID 12378824 DOI: 10.1016/S1537-1891(02)00127-1  0.375
2002 Hampl V, Bíbová J, Stranák Z, Wu X, Michelakis ED, Hashimoto K, Archer SL. Hypoxic fetoplacental vasoconstriction in humans is mediated by potassium channel inhibition. American Journal of Physiology. Heart and Circulatory Physiology. 283: H2440-9. PMID 12388256 DOI: 10.1152/Ajpheart.01033.2001  0.343
2002 Michelakis ED, Rebeyka I, Wu X, Nsair A, Thébaud B, Hashimoto K, Dyck JR, Haromy A, Harry G, Barr A, Archer SL. O2 sensing in the human ductus arteriosus: regulation of voltage-gated K+ channels in smooth muscle cells by a mitochondrial redox sensor. Circulation Research. 91: 478-86. PMID 12242265 DOI: 10.1161/01.Res.0000035057.63303.D1  0.307
2002 Archer S, Michelakis E. The mechanism(s) of hypoxic pulmonary vasoconstriction: potassium channels, redox O(2) sensors, and controversies. News in Physiological Sciences : An International Journal of Physiology Produced Jointly by the International Union of Physiological Sciences and the American Physiological Society. 17: 131-7. PMID 12136039 DOI: 10.1152/Nips.01388.2002  0.429
2002 Michelakis ED, Hampl V, Nsair A, Wu X, Harry G, Haromy A, Gurtu R, Archer SL. Diversity in mitochondrial function explains differences in vascular oxygen sensing. Circulation Research. 90: 1307-15. PMID 12089069 DOI: 10.1161/01.Res.0000024689.07590.C2  0.371
2002 Thébaud B, Michelakis E, Wu XC, Harry G, Hashimoto K, Archer SL. Sildenafil reverses O2 constriction of the rabbit ductus arteriosus by inhibiting type 5 phosphodiesterase and activating BK(Ca) channels. Pediatric Research. 52: 19-24. PMID 12084842 DOI: 10.1203/00006450-200207000-00006  0.321
2002 Michelakis E, Tymchak W, Lien D, Webster L, Hashimoto K, Archer S. Oral sildenafil is an effective and specific pulmonary vasodilator in patients with pulmonary arterial hypertension: comparison with inhaled nitric oxide. Circulation. 105: 2398-403. PMID 12021227 DOI: 10.1161/01.Cir.0000016641.12984.Dc  0.468
2002 Michelakis ED, Dyck JR, McMurtry MS, Wang S, Wu XC, Moudgil R, Hashimoto K, Puttagunta L, Archer SL. Gene transfer and metabolic modulators as new therapies for pulmonary hypertension. Increasing expression and activity of potassium channels in rat and human models. Advances in Experimental Medicine and Biology. 502: 401-18. PMID 11950153 DOI: 10.1007/978-1-4757-3401-0_26  0.46
2002 Michelakis ED, McMurtry MS, Wu XC, Dyck JR, Moudgil R, Hopkins TA, Lopaschuk GD, Puttagunta L, Waite R, Archer SL. Dichloroacetate, a metabolic modulator, prevents and reverses chronic hypoxic pulmonary hypertension in rats: role of increased expression and activity of voltage-gated potassium channels. Circulation. 105: 244-50. PMID 11790708 DOI: 10.1161/Hc0202.101974  0.359
2002 Wang S, Michelakis E, Dyck J, Nsair A, Wu X, Moudgil R, Hashimoto K, Archer S. Gene transfer in human pulmonary arteries using adenoviral vectors: increasing expression and activity of potassium channels The Journal of Heart and Lung Transplantation. 21: 65. DOI: 10.1016/S1053-2498(01)00463-6  0.31
2001 Archer SL, London B, Hampl V, Wu X, Nsair A, Puttagunta L, Hashimoto K, Waite RE, Michelakis ED. Impairment of hypoxic pulmonary vasoconstriction in mice lacking the voltage-gated potassium channel Kv1.5. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 1801-3. PMID 11481235 DOI: 10.1096/Fj.00-0649Fje  0.317
2001 Reeve HL, Michelakis E, Nelson DP, Weir EK, Archer SL. Alterations in a redox oxygen sensing mechanism in chronic hypoxia. Journal of Applied Physiology (Bethesda, Md. : 1985). 90: 2249-56. PMID 11356790 DOI: 10.1152/Jappl.2001.90.6.2249  0.393
2001 Reeve HL, Tolarova S, Nelson DP, Archer S, Weir EK. Redox control of oxygen sensing in the rabbit ductus arteriosus. The Journal of Physiology. 533: 253-61. PMID 11351032 DOI: 10.1111/J.1469-7793.2001.0253B.X  0.31
2001 Michelakis ED, Weir EK, Wu X, Nsair A, Waite R, Hashimoto K, Puttagunta L, Knaus HG, Archer SL. Potassium channels regulate tone in rat pulmonary veins. American Journal of Physiology. Lung Cellular and Molecular Physiology. 280: L1138-47. PMID 11350792 DOI: 10.1152/Ajplung.2001.280.6.L1138  0.337
2001 Michelakis E, Nsair A, Wu X, Hashimoto K, Archer S. The opposing effects of hypoxia on pulmonary versus renal arteries are regulated by a mitochondria-based O2 sensor Journal of Molecular and Cellular Cardiology. 33: A172. DOI: 10.1016/S0022-2828(01)90660-1  0.391
2001 Archer S, Michelakis E. A pulmonary vascular redox O2 sensor Journal of Molecular and Cellular Cardiology. 33: A158. DOI: 10.1016/S0022-2828(01)90607-8  0.345
2000 Archer S, Rich S. Primary pulmonary hypertension: a vascular biology and translational research "Work in progress". Circulation. 102: 2781-91. PMID 11094047 DOI: 10.1161/01.Cir.102.22.2781  0.429
2000 Archer SL, Weir EK, Reeve HL, Michelakis E. Molecular identification of O2 sensors and O2-sensitive potassium channels in the pulmonary circulation. Advances in Experimental Medicine and Biology. 475: 219-40. PMID 10849663 DOI: 10.1007/0-306-46825-5_21  0.36
1999 Cornfield DN, Martin EB, Hampl V, Archer SL. Aerosol delivery of diethylenetriamine/nitric oxide, a nitric oxide adduct, causes selective pulmonary vasodilation in perinatal lambs. The Journal of Laboratory and Clinical Medicine. 134: 419-25. PMID 10521090 DOI: 10.1016/S0022-2143(99)90158-0  0.469
1999 Reeve HL, Archer SL, Soper M, Weir EK. Dexfenfluramine increases pulmonary artery smooth muscle intracellular Ca2+, independent of membrane potential. The American Journal of Physiology. 277: L662-6. PMID 10484475 DOI: 10.1152/Ajplung.1999.277.3.L662  0.343
1999 Archer SL, Reeve HL, Michelakis E, Puttagunta L, Waite R, Nelson DP, Dinauer MC, Weir EK. O2 sensing is preserved in mice lacking the gp91 phox subunit of NADPH oxidase. Proceedings of the National Academy of Sciences of the United States of America. 96: 7944-9. PMID 10393927 DOI: 10.1073/Pnas.96.14.7944  0.377
1999 Reeve HL, Nelson DP, Archer SL, Weir EK. Effects of fluoxetine, phentermine, and venlafaxine on pulmonary arterial pressure and electrophysiology. The American Journal of Physiology. 276: L213-9. PMID 9950882 DOI: 10.1152/Ajplung.1999.276.2.L213  0.425
1998 Reeve HL, Weir EK, Archer SL, Cornfield DN. A maturational shift in pulmonary K+ channels, from Ca2+ sensitive to voltage dependent. The American Journal of Physiology. 275: L1019-25. PMID 9843837 DOI: 10.1152/Ajplung.1998.275.6.L1019  0.329
1998 Archer SL, Djaballah K, Humbert M, Weir KE, Fartoukh M, Dall'ava-Santucci J, Mercier JC, Simonneau G, Dinh-Xuan AT. Nitric oxide deficiency in fenfluramine- and dexfenfluramine-induced pulmonary hypertension. American Journal of Respiratory and Critical Care Medicine. 158: 1061-7. PMID 9769261 DOI: 10.1164/Ajrccm.158.4.9802113  0.386
1998 Weir EK, Reeve HL, Johnson G, Michelakis ED, Nelson DP, Archer SL. A role for potassium channels in smooth muscle cells and platelets in the etiology of primary pulmonary hypertension. Chest. 114: 200S-204S. PMID 9741569 DOI: 10.1378/Chest.114.3_Supplement.200S  0.448
1998 Weir EK, Reeve HL, Peterson DA, Michelakis ED, Nelson DP, Archer SL. Pulmonary vasoconstriction, oxygen sensing, and the role of ion channels: Thomas A. Neff lecture. Chest. 114: 17S-22S. PMID 9676606 DOI: 10.1378/Chest.114.1_Supplement.17S-A  0.354
1998 Archer SL, Souil E, Dinh-Xuan AT, Schremmer B, Mercier JC, El Yaagoubi A, Nguyen-Huu L, Reeve HL, Hampl V. Molecular identification of the role of voltage-gated K+ channels, Kv1.5 and Kv2.1, in hypoxic pulmonary vasoconstriction and control of resting membrane potential in rat pulmonary artery myocytes. The Journal of Clinical Investigation. 101: 2319-30. PMID 9616203 DOI: 10.1172/Jci333  0.414
1998 Weir EK, Reeve HL, Tolarova S, Cornfield DN, Nelson DP, Archer SL. Mechanisms of Pulmonary Vasodilatation and Ductus Arteriosus Constriction by Normoxia The Keio Journal of Medicine. 45: 400-409. DOI: 10.1007/978-4-431-68476-3_50  0.42
1997 Reeve HL, Archer SL, Weir EK. Ion channels in the pulmonary vasculature. Pulmonary Pharmacology & Therapeutics. 10: 243-52. PMID 9778487 DOI: 10.1006/Pupt.1998.0107  0.352
1997 Weir EK, Reeve HL, Cornfield DN, Tristani-Firouzi M, Peterson DA, Archer SL. Diversity of response in vascular smooth muscle cells to changes in oxygen tension. Kidney International. 51: 462-6. PMID 9027722 DOI: 10.1038/Ki.1997.62  0.411
1997 Reeve HL, Archer SL, Weir EK, Cornfield DN. Developmental regulated changes in pulmonary artery smooth muscle cell potassium channels controls the resting membrane potential and oxygen sensing♦ 1574 Pediatric Research. 41: 265-265. DOI: 10.1203/00006450-199704001-01593  0.404
1996 Tristani-Firouzi M, Martin EB, Tolarova S, Weir EK, Archer SL, Cornfield DN. Ventilation-induced pulmonary vasodilation at birth is modulated by potassium channel activity. The American Journal of Physiology. 271: H2353-9. PMID 8997293 DOI: 10.1152/Ajpheart.1996.271.6.H2353  0.446
1996 Tristani-Firouzi M, Reeve HL, Tolarova S, Weir EK, Archer SL. Oxygen-induced constriction of rabbit ductus arteriosus occurs via inhibition of a 4-aminopyridine-, voltage-sensitive potassium channel. The Journal of Clinical Investigation. 98: 1959-65. PMID 8903313 DOI: 10.1172/Jci118999  0.342
1996 Weir EK, Reeve HL, Huang JM, Michelakis E, Nelson DP, Hampl V, Archer SL. Anorexic agents aminorex, fenfluramine, and dexfenfluramine inhibit potassium current in rat pulmonary vascular smooth muscle and cause pulmonary vasoconstriction. Circulation. 94: 2216-20. PMID 8901674 DOI: 10.1161/01.Cir.94.9.2216  0.479
1996 Hampl V, Tristani-Firouzi M, Nelson DP, Archer SL. Chronic infusion of nitric oxide in experimental pulmonary hypertension: pulmonary pressure-flow analysis. The European Respiratory Journal. 9: 1475-81. PMID 8836662 DOI: 10.1183/09031936.96.09071475  0.461
1996 Sidney EJ, Hampl V, Nelson DP, Archer SL, Foegh ML, Cathapermal SS, Weir EK. The somatostatin analog angiopeptin does not reduce chronic hypoxic pulmonary hypertension in rats. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 213: 43-9. PMID 8820822 DOI: 10.3181/00379727-213-44034  0.448
1996 Cornfield DN, Reeve HL, Tolarova S, Weir EK, Archer S. Oxygen causes fetal pulmonary vasodilation through activation of a calcium-dependent potassium channel. Proceedings of the National Academy of Sciences of the United States of America. 93: 8089-94. PMID 8755608 DOI: 10.1073/Pnas.93.15.8089  0.439
1996 Archer SL. Diversity of phenotype and function of vascular smooth muscle cells. The Journal of Laboratory and Clinical Medicine. 127: 524-9. PMID 8648256 DOI: 10.1016/S0022-2143(96)90142-0  0.365
1996 Archer SL, Mike D, Crow J, Long W, Weir EK. A placebo-controlled trial of prostacyclin in acute respiratory failure in COPD. Chest. 109: 750-5. PMID 8617086 DOI: 10.1378/Chest.109.3.750  0.444
1996 Archer SL, Huang JM, Reeve HL, Hampl V, Tolarová S, Michelakis E, Weir EK. Differential distribution of electrophysiologically distinct myocytes in conduit and resistance arteries determines their response to nitric oxide and hypoxia. Circulation Research. 78: 431-42. PMID 8593702 DOI: 10.1161/01.Res.78.3.431  0.382
1996 Reeve HL, Archer SL, Weir EK, Cornfield DN. OXYGEN CAUSES ACTIVATION OF A Ca2+-DEPENDENT POTASSIUM CHANNEL IN FETAL PULMONARY ARTERY SMOOTH MUSCLE CELLS. † 2068 Pediatric Research. 39: 347-347. DOI: 10.1203/00006450-199604001-02092  0.408
1996 Martin EB, Tolarova S, Weir EK, Archer SL, Cornfield DN. Aerosol Delivery Of Detano, A Nitric Oxide Adduct, Causes Selective And Sustained Perinatal Pulmonary Vasodilation † 2019 Pediatric Research. 39: 339-339. DOI: 10.1203/00006450-199604001-02043  0.421
1996 Hampl V, Tristani-Firouzi M, Hutsell TC, Archer SL. Nebulized nitric oxide/nucleophile adduct reduces chronic pulmonary hypertension Cardiovascular Research. 31: 55-62. DOI: 10.1016/S0008-6363(95)00172-7  0.474
1995 Reeve HL, Weir EK, Nelson DP, Peterson DA, Archer SL. Opposing effects of oxidants and antioxidants on K+ channel activity and tone in rat vascular tissue. Experimental Physiology. 80: 825-34. PMID 8546871 DOI: 10.1113/Expphysiol.1995.Sp003890  0.379
1995 Simon G, Archer SL. Hypertensive urgency due to cholesterol embolization of kidneys American Journal of Hypertension. 8: 954-956. PMID 8541013 DOI: 10.1016/0895-7061(95)00223-C  0.348
1995 Archer SL, Hampl V, Nelson DP, Sidney E, Peterson DA, Weir EK. Dithionite increases radical formation and decreases vasoconstriction in the lung. Evidence that dithionite does not mimic alveolar hypoxia. Circulation Research. 77: 174-81. PMID 7788875 DOI: 10.1161/01.Res.77.1.174  0.399
1995 Weir EK, Archer SL. The mechanism of acute hypoxic pulmonary vasoconstriction: the tale of two channels. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 9: 183-9. PMID 7781921 DOI: 10.1096/Fasebj.9.2.7781921  0.453
1995 Chandrashekhar y, McKenzie Z, Nelson D, Archer S, Anand IS. 779-2 L-Arginine Does not Acutely Influence Endothelial Function in Either Resistance or Conduit Arteries of Dogs with Pacing Induced Congestive Heart Failure Journal of the American College of Cardiology. 25: 296A. DOI: 10.1016/0735-1097(95)92686-Y  0.32
1994 Weir EK, Wyatt CN, Reeve HL, Huang J, Archer SL, Peers C. Diphenyleneiodonium inhibits both potassium and calcium currents in isolated pulmonary artery smooth muscle cells. Journal of Applied Physiology (Bethesda, Md. : 1985). 76: 2611-5. PMID 7928890 DOI: 10.1152/Jappl.1994.76.6.2611  0.428
1994 Archer SL, Huang JM, Hampl V, Nelson DP, Shultz PJ, Weir EK. Nitric oxide and cGMP cause vasorelaxation by activation of a charybdotoxin-sensitive K channel by cGMP-dependent protein kinase. Proceedings of the National Academy of Sciences of the United States of America. 91: 7583-7. PMID 7519783 DOI: 10.1073/Pnas.91.16.7583  0.33
1994 Isaacson TC, Hampl V, Weir EK, Nelson DP, Archer SL. Increased endothelium-derived NO in hypertensive pulmonary circulation of chronically hypoxic rats. Journal of Applied Physiology (Bethesda, Md. : 1985). 76: 933-40. PMID 7513687 DOI: 10.1152/Jappl.1994.76.2.933  0.35
1994 Archer S, Hampl V, McKenzie Z, Nelson D, Huang J, Shultz P, Weir E. Role of Endothelial-Derived Nitric Oxide in Normal and Hypertensive Pulmonary Vasculature Seminars in Respiratory and Critical Care Medicine. 15: 179-189. DOI: 10.1055/S-2007-1006361  0.417
1993 Toher C, Krug H, Archer SL. Diagnosis of Pulmonary Vein Varix by Transesophageal Echocardiography Chest. 103: 1901-1903. PMID 8404126 DOI: 10.1378/Chest.103.6.1901  0.441
1993 Archer SL, Huang J, Henry T, Peterson D, Weir EK. A redox-based O2 sensor in rat pulmonary vasculature. Circulation Research. 73: 1100-12. PMID 8222081 DOI: 10.1161/01.Res.73.6.1100  0.458
1993 Hampl V, Archer SL, Bach R, Nelson DP, Weir EK. Chronic hypoxic pulmonary hypertension. Is thrombin involved? The American Review of Respiratory Disease. 148: 1043-8. PMID 8214923 DOI: 10.1164/Ajrccm/148.4_Pt_1.1043  0.471
1993 Hampl V, Archer SL, Nelson DP, Weir EK. Chronic EDRF inhibition and hypoxia: effects on pulmonary circulation and systemic blood pressure. Journal of Applied Physiology (Bethesda, Md. : 1985). 75: 1748-57. PMID 7506706 DOI: 10.1152/Jappl.1993.75.4.1748  0.421
1992 Post JM, Hume JR, Archer SL, Weir EK. Direct role for potassium channel inhibition in hypoxic pulmonary vasoconstriction American Journal of Physiology - Cell Physiology. 262. PMID 1566816 DOI: 10.1152/Ajpcell.1992.262.4.C882  0.464
1992 Archer SL, Hampl V. NG-monomethyl-L-arginine causes nitric oxide synthesis in isolated arterial rings: trouble in paradise. Biochemical and Biophysical Research Communications. 188: 590-6. PMID 1445303 DOI: 10.1016/0006-291X(92)91097-A  0.324
1991 Archer SL, Cowan NJ. Measurement of endothelial cytosolic calcium concentration and nitric oxide production reveals discrete mechanisms of endothelium-dependent pulmonary vasodilatation. Circulation Research. 68: 1569-81. PMID 2036711 DOI: 10.1161/01.Res.68.6.1569  0.363
1990 Archer SL, Rist K, Nelson DP, DeMaster EG, Cowan N, Weir EK. Comparison of the hemodynamic effects of nitric oxide and endothelium-dependent vasodilators in intact lungs. Journal of Applied Physiology (Bethesda, Md. : 1985). 68: 735-47. PMID 2156794 DOI: 10.1152/Jappl.1990.68.2.735  0.449
1989 Archer SL, Peterson D, Nelson DP, DeMaster EG, Kelly B, Eaton JW, Weir EK. Oxygen radicals and antioxidant enzymes alter pulmonary vascular reactivity in the rat lung. Journal of Applied Physiology (Bethesda, Md. : 1985). 66: 102-11. PMID 2917913 DOI: 10.1152/Jappl.1989.66.1.102  0.411
1989 Archer SL, Nelson DP, Zimmer S, From AH, Weir EK. Hypoxic pulmonary vasoconstriction is unaltered by creatine depletion induced by dietary beta-guanidino propionic acid. Life Sciences. 45: 1081-8. PMID 2796598 DOI: 10.1016/0024-3205(89)90165-3  0.394
1989 Archer SL, Johnson GJ, Gebhard RL, Castleman WL, Levine AS, Westcott JY, Voelkel NF, Nelson DP, Weir EK. Effect of dietary fish oil on lung lipid profile and hypoxic pulmonary hypertension. Journal of Applied Physiology (Bethesda, Md. : 1985). 66: 1662-73. PMID 2732158 DOI: 10.1152/Jappl.1989.66.4.1662  0.355
1989 Archer SL, Nelson DP, Weir EK. Simultaneous measurement of O2 radicals and pulmonary vascular reactivity in rat lung. Journal of Applied Physiology (Bethesda, Md. : 1985). 67: 1903-11. PMID 2532193 DOI: 10.1152/Jappl.1989.67.5.1903  0.427
1989 Archer SL, Tolins JP, Raij L, Weir EK. Hypoxic pulmonary vasoconstriction is enhanced by inhibition of the synthesis of an endothelium derived relaxing factor. Biochemical and Biophysical Research Communications. 164: 1198-205. PMID 2480112 DOI: 10.1016/0006-291X(89)91796-8  0.39
1988 Weir EK, Archer SL, Edwards JE. Chronic primary and secondary thromboembolic pulmonary hypertension. Chest. 93: 149S-154S. PMID 3277816 DOI: 10.1378/Chest.93.3_Supplement.149S-A  0.428
1986 Archer SL, Chesler E, Cohn JN, Weir EK. ZK 36-374, a stable analog of prostacyclin, prevents acute hypoxic pulmonary hypertension in the dog. Journal of the American College of Cardiology. 8: 1189-94. PMID 2428854 DOI: 10.1016/S0735-1097(86)80400-4  0.446
1986 Archer SL, Kulik TJ, Chesler E, Weir EK. The effects of substance P on the preconstricted pulmonary vasculature of the anesthetized dog. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 183: 19-27. PMID 2428048 DOI: 10.3181/00379727-183-42381  0.41
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