Year |
Citation |
Score |
2023 |
Meng Y, Huang R. Site-specific methylation on α-N-terminus of peptides through chemical and enzymatic methods. Methods in Enzymology. 684: 113-133. PMID 37230586 DOI: 10.1016/bs.mie.2023.02.008 |
0.338 |
|
2020 |
Mackie BD, Chen D, Dong G, Dong C, Parker H, Tooley C, Noinaj N, Min J, Huang R. Selective Peptidomimetic Inhibitors of NTMT1/2: Rational design, synthesis, characterization, and crystallographic studies. Journal of Medicinal Chemistry. PMID 32689795 DOI: 10.1021/Acs.Jmedchem.0C00689 |
0.363 |
|
2020 |
Iyamu ID, Huang R. Development of fluorescence polarization-based competition assay for nicotinamide N-methyltransferase. Analytical Biochemistry. 113833. PMID 32622979 DOI: 10.1016/J.Ab.2020.113833 |
0.319 |
|
2020 |
Chen D, Dong C, Dong G, Srinivasan K, Min J, Noinaj N, Huang R. Probing the Plasticity in the Active Site of Protein N-terminal Methyltransferase 1 Using Bisubstrate Analogs. Journal of Medicinal Chemistry. PMID 32605369 DOI: 10.1021/Acs.Jmedchem.0C00770 |
0.328 |
|
2020 |
Al-Hamashi AA, Diaz K, Huang R. Non-Histone Arginine Methylation by Protein Arginine Methyltransferases. Current Protein & Peptide Science. PMID 32379587 DOI: 10.2174/1389203721666200507091952 |
0.346 |
|
2019 |
Chen D, Li L, Diaz K, Iyamu ID, Yadav R, Noinaj N, Huang R. Novel Propargyl-linked Bisubstrate Analogs as Tight-binding Inhibitors for Nicotinamide N-Methyltransferase. Journal of Medicinal Chemistry. PMID 31724854 DOI: 10.1021/Acs.Jmedchem.9B01255 |
0.326 |
|
2019 |
Chen D, Dong G, Noinaj N, Huang R. Discovery of bisubstrate inhibitors for protein N-terminal methyltransferase 1. Journal of Medicinal Chemistry. PMID 30883119 DOI: 10.1021/Acs.Jmedchem.9B00206 |
0.32 |
|
2018 |
Huang R. Chemical Biology of Protein N-terminal Methyltransferases. Chembiochem : a European Journal of Chemical Biology. PMID 30479015 DOI: 10.1002/Cbic.201800615 |
0.331 |
|
2016 |
Zhang G, Huang R. Facile synthesis of SAM-peptide conjugates through alkyl linkers targeting protein N-terminal methyltransferase 1. Rsc Advances. 6: 6768-6771. PMID 27588169 DOI: 10.1039/C5Ra20625A |
0.398 |
|
2015 |
Dong C, Mao Y, Tempel W, Qin S, Li L, Loppnau P, Huang R, Min J. Structural basis for substrate recognition by the human N-terminal methyltransferase 1. Genes & Development. PMID 26543161 DOI: 10.1101/Gad.270611.115 |
0.304 |
|
2015 |
Richardson SL, Hanjra P, Zhang G, Mackie BD, Peterson DL, Huang R. A direct, ratiometric, and quantitative MALDI-MS assay for protein methyltransferases and acetyltransferases. Analytical Biochemistry. 478: 59-64. PMID 25778392 DOI: 10.1016/J.Ab.2015.03.007 |
0.341 |
|
2015 |
Richardson SL, Mao Y, Zhang G, Hanjra P, Peterson DL, Huang R. Kinetic mechanism of protein N-terminal methyltransferase 1. The Journal of Biological Chemistry. 290: 11601-10. PMID 25771539 DOI: 10.1074/Jbc.M114.626846 |
0.325 |
|
2015 |
Zhang G, Richardson SL, Mao Y, Huang R. Design, synthesis, and kinetic analysis of potent protein N-terminal methyltransferase 1 inhibitors. Organic & Biomolecular Chemistry. 13: 4149-54. PMID 25712161 DOI: 10.1039/C5Ob00120J |
0.361 |
|
2014 |
Prusevich P, Kalin JH, Ming SA, Basso M, Givens J, Li X, Hu J, Taylor MS, Cieniewicz AM, Hsiao PY, Huang R, Roberson H, Adejola N, Avery LB, Casero RA, et al. A selective phenelzine analogue inhibitor of histone demethylase LSD1. Acs Chemical Biology. 9: 1284-93. PMID 24707965 DOI: 10.1021/Cb500018S |
0.521 |
|
2013 |
Nahomi RB, Huang R, Nandi SK, Wang B, Padmanabha S, Santhoshkumar P, Filipek S, Biswas A, Nagaraj RH. Acetylation of lysine 92 improves the chaperone and anti-apoptotic activities of human αB-crystallin. Biochemistry. 52: 8126-38. PMID 24128140 DOI: 10.1021/Bi400638S |
0.343 |
|
2013 |
Huang R, Oh H, Arrendale A, Martin VA, Galan J, Workman EJ, Stout JR, Walczak CE, Tao WA, Borch RF, Geahlen RL. Intracellular targets for a phosphotyrosine peptidomimetic include the mitotic kinesin, MCAK. Biochemical Pharmacology. 86: 597-611. PMID 23830822 DOI: 10.1016/J.Bcp.2013.06.024 |
0.594 |
|
2011 |
Marian C, Huang R, Borch RF. Design and synthesis of a potential SH2 domain inhibitor bearing a stereodiversified 1,4-cis-enediol scaffold. Tetrahedron. 67: 10216-10221. PMID 22199405 DOI: 10.1016/J.Tet.2011.10.014 |
0.637 |
|
2011 |
Blair LP, Avaritt NL, Huang R, Cole PA, Taverna SD, Tackett AJ. MassSQUIRM: An assay for quantitative measurement of lysine demethylase activity. Epigenetics : Official Journal of the Dna Methylation Society. 6: 490-9. PMID 21273814 DOI: 10.4161/Epi.6.4.14531 |
0.39 |
|
2011 |
Arrendale AA, Huang R, Geahlen R, Borch R. Abstract B184: Design, synthesis, and evaluation of novel mitotic centromere-associated kinesin (MCAK) inhibitors. Molecular Cancer Therapeutics. 10. DOI: 10.1158/1535-7163.Targ-11-B184 |
0.591 |
|
2010 |
Huang R, Holbert MA, Tarrant MK, Curtet S, Colquhoun DR, Dancy BM, Dancy BC, Hwang Y, Tang Y, Meeth K, Marmorstein R, Cole RN, Khochbin S, Cole PA. Site-specific introduction of an acetyl-lysine mimic into peptides and proteins by cysteine alkylation. Journal of the American Chemical Society. 132: 9986-7. PMID 20608637 DOI: 10.1021/Ja103954U |
0.48 |
|
2010 |
Huang R, Martinez-Ferrando I, Cole PA. Enhanced interrogation: emerging strategies for cell signaling inhibition. Nature Structural & Molecular Biology. 17: 646-9. PMID 20520657 DOI: 10.1038/Nsmb0610-646 |
0.477 |
|
Show low-probability matches. |