Rohit Ramachandran - Publications

Affiliations: 
2008 Imperial College, London, London, England, United Kingdom 

101 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Dan A, Vaswani H, Tomnikova A, Ramachandran R. Multi-dimensional population balance model development using a breakage mode probability kernel for prediction of multiple granule attributes. Pharmaceutical Development and Technology. 1-23. PMID 37410512 DOI: 10.1080/10837450.2023.2231074  0.408
2022 Zidan A, Kotamarthy L, Ramachandran R, Ashraf M, O'Connor T. Optimization of screw design for continuous wet granulation: A case study of metoprolol succinate ER tablets. International Journal of Pharmaceutics. 623: 121964. PMID 35764264 DOI: 10.1016/j.ijpharm.2022.121964  0.324
2022 Kotamarthy L, Feng X, Alayoubi A, Kumar Bolla P, Ramachandran R, Ashraf M, O'Connor T, Zidan A. Switching from batch to continuous granulation: A case study of metoprolol succinate ER tablets. International Journal of Pharmaceutics. 617: 121598. PMID 35202728 DOI: 10.1016/j.ijpharm.2022.121598  0.309
2022 Baranwal Y, Román-Ospino AD, Li J, Razavi SM, Muzzio FJ, Ramachandran R. Prediction of entire tablet formulations from pure powder components' spectra via a two-step non-linear optimization methodology. International Journal of Pharmaceutics. 615: 121472. PMID 35063595 DOI: 10.1016/j.ijpharm.2022.121472  0.339
2021 Muthancheri I, Ramachandran R. A Hybrid Model to Predict Formulation Dependent Granule Growth in a Bi-Component Wet Granulation Process. Pharmaceutics. 13. PMID 34959342 DOI: 10.3390/pharmaceutics13122063  0.366
2021 Muddu SV, Kotamarthy L, Ramachandran R. A Semi-Mechanistic Prediction of Residence Time Metrics in Twin Screw Granulation. Pharmaceutics. 13. PMID 33809652 DOI: 10.3390/pharmaceutics13030393  0.302
2021 Sampat C, Ramachandran R. Identification of Granule Growth Regimes in High Shear Wet Granulation Processes Using a Physics-Constrained Neural Network Processes. 9: 737. DOI: 10.3390/PR9050737  0.314
2020 Kotamarthy L, Metta N, Ramachandran R. Understanding the Effect of Granulation and Milling Process Parameters on the Quality Attributes of Milled Granules Processes. 8: 683. DOI: 10.3390/pr8060683  0.381
2020 Muthancheri I, Ramachandran R. Mechanistic understanding of granule growth behavior in bi-component wet granulation processes with wettability differentials Powder Technology. 367: 841-859. DOI: 10.1016/J.Powtec.2020.04.016  0.374
2020 Moroney KM, Cronin P, Adeleye OA, Schaller BE, Howard MA, Castro-Dominguez B, Ramachandran R, Walker GM. An evaluation of the Johanson model for roller compaction process development for a high dose API Powder Technology. 366: 82-95. DOI: 10.1016/J.Powtec.2020.02.058  0.459
2020 Gao T, Singaravelu AS, Oka S, Ramachandran R, Štepánek F, Chawla N, Emady HN. Powder bed packing and API content homogeneity of granules in single drop granule formation Powder Technology. 366: 12-21. DOI: 10.1016/J.Powtec.2020.02.039  0.416
2020 Sampat C, Baranwal Y, Ramachandran R. Accelerating multi-dimensional population balance model simulations via a highly scalable framework using GPUs Computers & Chemical Engineering. 140: 106935. DOI: 10.1016/J.Compchemeng.2020.106935  0.32
2020 Muthancheri I, Long B, Ryan KM, Padrela L, Ramachandran R. Development and validation of a two-dimensional population balance model for a supercritical CO2 antisolvent batch crystallization process Advanced Powder Technology. 31: 3191-3204. DOI: 10.1016/J.Apt.2020.06.008  0.505
2020 Tamrakar A, Zheng A, Piccione PM, Ramachandran R. Investigating particle-level dynamics to understand bulk behavior in a lab-scale Agitated Filter Dryer (AFD) using Discrete Element Method (DEM) Advanced Powder Technology. 31: 477-492. DOI: 10.1016/J.Apt.2019.11.004  0.451
2020 Metta N, Ramachandran R, Ierapetritou M. A Computationally Efficient Surrogate-Based Reduction of a Multiscale Comill Process Model Journal of Pharmaceutical Innovation. 15: 1-21. DOI: 10.1007/S12247-019-09388-2  0.553
2019 Román-Ospino AD, Tamrakar A, Igne B, Towns Dimaso E, Airiau C, Clancy DJ, Pereira G, Muzzio FJ, Singh R, Ramachandran R. Characterization of NIR interfaces for the feeding and in-line monitoring of a continuous granulation process. International Journal of Pharmaceutics. 118848. PMID 31812798 DOI: 10.1016/J.Ijpharm.2019.118848  0.348
2019 Baranwal Y, Román-Ospino AD, Keyvan G, Ha JM, Hong EP, Muzzio FJ, Ramachandran R. Prediction of dissolution profiles by non-destructive NIR spectroscopy in bilayer tablets. International Journal of Pharmaceutics. PMID 31085258 DOI: 10.1016/J.Ijpharm.2019.05.022  0.363
2019 Metta N, Ghijs M, Schäfer E, Kumar A, Cappuyns P, Assche IV, Singh R, Ramachandran R, Beer TD, Ierapetritou M, Nopens I. Dynamic Flowsheet Model Development and Sensitivity Analysis of a Continuous Pharmaceutical Tablet Manufacturing Process Using the Wet Granulation Route Processes. 7: 234. DOI: 10.3390/PR7040234  0.439
2019 Tamrakar A, Ramachandran R. CFD–DEM–PBM coupled model development and validation of a 3D top-spray fluidized bed wet granulation process Computers & Chemical Engineering. 125: 249-270. DOI: 10.1016/J.Compchemeng.2019.01.023  0.526
2019 Tamrakar A, Chen SW, Ramachandran R. A DEM model-based study to quantitatively compare the effect of wet and dry binder addition in high-shear wet granulation processes Chemical Engineering Research & Design. 142: 307-326. DOI: 10.1016/J.Cherd.2018.12.016  0.435
2019 Meng W, Dvořák J, Kumar R, Hofmeister R, Štěpánek F, Ramachandran R, Muzzio FJ. Continuous high-shear granulation: Mechanistic understanding of the influence of process parameters on critical quality attributes via elucidating the internal physical and chemical microstructure Advanced Powder Technology. 30: 1765-1781. DOI: 10.1016/J.Apt.2019.04.028  0.455
2019 Meng W, Román-Ospino AD, Panikar SS, O'Callaghan C, Gilliam SJ, Ramachandran R, Muzzio FJ. Advanced process design and understanding of continuous twin-screw granulation via implementation of in-line process analytical technologies Advanced Powder Technology. 30: 879-894. DOI: 10.1016/J.Apt.2019.01.017  0.5
2018 Meng W, Rao KS, Snee RD, Ramachandran R, Muzzio FJ. A comprehensive analysis and optimization of continuous twin-screw granulation processes via sequential experimentation strategy. International Journal of Pharmaceutics. PMID 30553003 DOI: 10.1016/J.Ijpharm.2018.12.009  0.445
2018 Gao T, Singaravelu ASS, Oka S, Ramachandran R, Štepánek F, Chawla N, Emady HN. Granule formation and structure from single drop impact on heterogeneous powder beds. International Journal of Pharmaceutics. PMID 30236649 DOI: 10.1016/J.Ijpharm.2018.09.036  0.393
2018 Metta N, Verstraeten M, Ghijs M, Kumar A, Schafer E, Singh R, Beer T, Nopens I, Cappuyns P, Assche IV, Ierapetritou M, Ramachandran R. Model development and prediction of particle size distribution, density and friability of a comilling operation in a continuous pharmaceutical manufacturing process. International Journal of Pharmaceutics. PMID 30076889 DOI: 10.1016/J.Ijpharm.2018.07.056  0.536
2018 Muddu S, Tamrakar A, Pandey P, Ramachandran R. Model Development and Validation of Fluid Bed Wet Granulation with Dry Binder Addition Using a Population Balance Model Methodology Processes. 6: 154. DOI: 10.3390/PR6090154  0.433
2018 Chaturbedi A, Pandey P, Bindra D, Reddy JP, Lang B, Buckley D, Ramachandran R. Predictive population balance model development and validation of the effect of high shear wet granulation process parameters on granule properties Powder Technology. 338: 391-401. DOI: 10.1016/J.Powtec.2018.07.004  0.483
2018 Sampat C, Bettencourt F, Baranwal Y, Paraskevakos I, Chaturbedi A, Karkala S, Jha S, Ramachandran R, Ierapetritou M. A parallel unidirectional coupled DEM-PBM model for the efficient simulation of computationally intensive particulate process systems Computers & Chemical Engineering. 119: 128-142. DOI: 10.1016/J.Compchemeng.2018.08.006  0.491
2018 Kataria A, Oka S, Smrčka D, Grof Z, Štěpánek F, Ramachandran R. A quantitative analysis of drug migration during granule drying Chemical Engineering Research & Design. 136: 199-206. DOI: 10.1016/J.Cherd.2018.05.001  0.378
2018 Metta N, Ierapetritou M, Ramachandran R. A multiscale DEM-PBM approach for a continuous comilling process using a mechanistically developed breakage kernel Chemical Engineering Science. 178: 211-221. DOI: 10.1016/J.Ces.2017.12.016  0.538
2018 Pereira GC, Muddu SV, Román-Ospino AD, Clancy D, Igne B, Airiau C, Muzzio FJ, Ierapetritou M, Ramachandran R, Singh R. Combined Feedforward/Feedback Control of an Integrated Continuous Granulation Process Journal of Pharmaceutical Innovation. 14: 259-285. DOI: 10.1007/S12247-018-9347-8  0.388
2017 Oka S, Smrčka D, Kataria A, Emady H, Muzzio F, Štěpánek F, Ramachandran R. Analysis of the origins of content non-uniformity in high-shear wet granulation. International Journal of Pharmaceutics. PMID 28627457 DOI: 10.1016/J.Ijpharm.2017.06.034  0.381
2017 Bettencourt FE, Chaturbedi A, Ramachandran R. Parallelization methods for efficient simulation of high dimensional population balance models of granulation Computers & Chemical Engineering. 107: 158-170. DOI: 10.1016/J.Compchemeng.2017.02.043  0.361
2017 Chaturbedi A, Bandi CK, Reddy D, Pandey P, Narang A, Bindra D, Tao L, Zhao J, Li J, Hussain M, Ramachandran R. Compartment based population balance model development of a high shear wet granulation process via dry and wet binder addition Chemical Engineering Research and Design. 123: 187-200. DOI: 10.1016/J.Cherd.2017.04.017  0.534
2017 Meng W, Oka S, Liu X, Omer T, Ramachandran R, Muzzio FJ. Effects of Process and Design Parameters on Granule Size Distribution in a Continuous High Shear Granulation Process Journal of Pharmaceutical Innovation. 12: 283-295. DOI: 10.1007/S12247-017-9288-7  0.407
2016 Meng W, Kotamarthy L, Panikar S, Sen M, Pradhan S, Marc M, Litster JD, Muzzio FJ, Ramachandran R. Statistical analysis and comparison of a continuous high shear granulator with a twin screw granulator: Effect of process parameters on critical granule attributes and granulation mechanisms. International Journal of Pharmaceutics. PMID 27633277 DOI: 10.1016/J.Ijpharm.2016.09.041  0.47
2016 Román-Ospino AD, Singh R, Ierapetritou M, Ramachandran R, Méndez R, Ortega-Zuñiga C, Muzzio FJ, Romañach RJ. Near infrared spectroscopic calibration models for real time monitoring of powder density. International Journal of Pharmaceutics. PMID 27543356 DOI: 10.1016/J.Ijpharm.2016.08.029  0.377
2016 Besenhard MO, Karkala S, Faulhammer E, Fathollahi S, Ramachandran R, Khinast JG. Continuous Feeding of Low-Dose APIs via Periodic Micro Dosing. International Journal of Pharmaceutics. PMID 27210736 DOI: 10.1016/J.Ijpharm.2016.05.033  0.357
2016 Tamrakar A, Gunadi A, Piccione PM, Ramachandran R. Dynamic agglomeration profiling during the drying phase in an agitated filter dyer: Parametric investigation and regime map studies Powder Technology. 303: 109-123. DOI: 10.1016/J.Powtec.2016.09.012  0.414
2016 Adepu M, Hate S, Bétard A, Oka S, Schongut M, Sen M, Sood Y, Wolf D, Wieland S, Stepanek F, Muzzio F, Glasser B, Ramachandran R. Quantitative validation and analysis of the regime map approach for the wet granulation of industrially relevant zirconium hydroxide powders Powder Technology. 294: 177-184. DOI: 10.1016/J.Powtec.2016.02.026  0.363
2016 Chaturbedi A, Pathak C, Deshpande K, Shapley N, Ramachandran R. Population balance model development and experimental validation for the heteroaggregation of oppositely charged micro- and nano-particles Chemical Engineering Research and Design. 113: 96-111. DOI: 10.1016/J.Cherd.2016.07.004  0.433
2016 Tamrakar A, Karkala S, Schankel D, Ramachandran R. Implementation of hybrid DEM-PBM approach to reduce the computational cost of powder mixing modeling Computer-Aided Chemical Engineering. 38: 1267-1273. DOI: 10.1016/B978-0-444-63428-3.50216-2  0.441
2016 Barrasso D, Ramachandran R. Discrete element modeling of solid dosage manufacturing processes Methods in Pharmacology and Toxicology. 32: 105-131. DOI: 10.1007/978-1-4939-2996-2_4  0.313
2015 Singh R, Román-Ospino AD, Romañach RJ, Ierapetritou M, Ramachandran R. Real time monitoring of powder blend bulk density for coupled feed-forward/feed-back control of a continuous direct compaction tablet manufacturing process. International Journal of Pharmaceutics. 495: 612-25. PMID 26386140 DOI: 10.1016/J.Ijpharm.2015.09.029  0.43
2015 Ghodbane M, Kulesa A, Yu HH, Maguire TJ, Schloss RR, Ramachandran R, Zahn JD, Yarmush ML. Development of a low-volume, highly sensitive microimmunoassay using computational fluid dynamics-driven multiobjective optimization. Microfluidics and Nanofluidics. 18: 199-214. PMID 25691853 DOI: 10.1007/S10404-014-1416-9  0.308
2015 Chaudhury A, Tamrakar A, Schöngut M, Smrčka D, Štěpánek F, Ramachandran R. Multidimensional population balance model development and validation of a reactive detergent granulation process Industrial and Engineering Chemistry Research. 54: 842-857. DOI: 10.1021/Ie503203Z  0.488
2015 Barrasso D, Tamrakar A, Ramachandran R. Model order reduction of a multi-scale PBM-DEM description of a wet granulation process via ANN Procedia Engineering. 102: 1295-1304. DOI: 10.1016/J.Proeng.2015.01.260  0.491
2015 Oka S, Emady H, Kašpar O, Tokárová V, Muzzio F, Štěpánek F, Ramachandran R. The effects of improper mixing and preferential wetting of active and excipient ingredients on content uniformity in high shear wet granulation Powder Technology. 278: 266-277. DOI: 10.1016/J.Powtec.2015.03.018  0.452
2015 Barrasso D, El Hagrasy A, Litster JD, Ramachandran R. Multi-dimensional population balance model development and validation for a twin screw granulation process Powder Technology. 270: 612-621. DOI: 10.1016/J.Powtec.2014.06.035  0.559
2015 Chaudhury A, Armenante ME, Ramachandran R. Compartment based population balance modeling of a high shear wet granulation process using data analytics Chemical Engineering Research and Design. 95: 211-228. DOI: 10.1016/J.Cherd.2014.10.024  0.528
2015 Barrasso D, Ramachandran R. Multi-scale modeling of granulation processes: Bi-directional coupling of PBM with DEM via collision frequencies Chemical Engineering Research and Design. 93: 304-317. DOI: 10.1016/J.Cherd.2014.04.016  0.512
2015 Barrasso D, Eppinger T, Pereira FE, Aglave R, Debus K, Bermingham SK, Ramachandran R. A multi-scale, mechanistic model of a wet granulation process using a novel bi-directional PBM-DEM coupling algorithm Chemical Engineering Science. 123: 500-513. DOI: 10.1016/J.Ces.2014.11.011  0.571
2015 Wu S, Panikar SS, Singh R, Zhang J, Glasser B, Ramachandran R. A systematic framework to monitor mulling processes using Near Infrared spectroscopy Advanced Powder Technology. DOI: 10.1016/J.Apt.2016.03.022  0.387
2015 Oka S, Kašpar O, Tokárová V, Sowrirajan K, Wu H, Khan M, Muzzio F, Štěpánek F, Ramachandran R. A quantitative study of the effect of process parameters on key granule characteristics in a high shear wet granulation process involving a two component pharmaceutical blend Advanced Powder Technology. 26: 315-322. DOI: 10.1016/J.Apt.2014.10.012  0.497
2015 Singh R, Muzzio F, Ierapetritou M, Ramachandran R. Plant-Wide Control of a Continuous Tablet Manufacturing for Quality-By-Design Based Pharmaceutical Manufacturing Computer Aided Chemical Engineering. 37: 2183-2188. DOI: 10.1016/B978-0-444-63576-1.50058-3  0.385
2015 Barrasso D, Ramachandran R. Qualitative Assessment of a Multi-Scale, Compartmental PBM-DEM Model of a Continuous Twin-Screw Wet Granulation Process Journal of Pharmaceutical Innovation. 1-19. DOI: 10.1007/S12247-015-9240-7  0.534
2015 Singh R, Sen M, Ierapetritou M, Ramachandran R. Integrated Moving Horizon-Based Dynamic Real-Time Optimization and Hybrid MPC-PID Control of a Direct Compaction Continuous Tablet Manufacturing Process Journal of Pharmaceutical Innovation. 10: 233-253. DOI: 10.1007/S12247-015-9221-X  0.397
2015 Chaudhury A, Sen M, Barrasso D, Ramachandran R. Population balance models for pharmaceutical processes Methods in Pharmacology and Toxicology. 32: 43-83. DOI: 10.1007/978-1-4939-2996-2_2  0.352
2014 Zhang J, Ying Y, Pielecha-Safira B, Bilgili E, Ramachandran R, Romañach R, Davé RN, Iqbal Z. Raman spectroscopy for in-line and off-line quantification of poorly soluble drugs in strip films. International Journal of Pharmaceutics. 475: 428-37. PMID 25173638 DOI: 10.1016/J.Ijpharm.2014.08.051  0.327
2014 Singh R, Sahay A, Karry KM, Muzzio F, Ierapetritou M, Ramachandran R. Implementation of an advanced hybrid MPC-PID control system using PAT tools into a direct compaction continuous pharmaceutical tablet manufacturing pilot plant. International Journal of Pharmaceutics. 473: 38-54. PMID 24974987 DOI: 10.1016/J.Ijpharm.2014.06.045  0.37
2014 Singh R, Sahay A, Muzzio F, Ierapetritou M, Ramachandran R. A systematic framework for onsite design and implementation of a control system in a continuous tablet manufacturing process Computers and Chemical Engineering. 66: 186-200. DOI: 10.1016/J.Compchemeng.2014.02.029  0.408
2014 Chaudhury A, Oseledets I, Ramachandran R. A computationally efficient technique for the solution of multi-dimensional PBMs of granulation via tensor decomposition Computers and Chemical Engineering. 61: 234-244. DOI: 10.1016/J.Compchemeng.2013.10.020  0.442
2014 Besenhard MO, Chaudhury A, Vetter T, Ramachandran R, Khinast JG. Evaluation of Parameter Estimation Methods for Crystallization Processes Modeled via Population Balance Equations Chemical Engineering Research and Design. DOI: 10.1016/J.Cherd.2014.08.004  0.394
2014 Barrasso D, Tamrakar A, Ramachandran R. A reduced order PBM-ANN model of a multi-scale PBM-DEM description of a wet granulation process Chemical Engineering Science. 119: 319-329. DOI: 10.1016/J.Ces.2014.08.005  0.527
2014 Chaudhury A, Wu H, Khan M, Ramachandran R. A mechanistic population balance model for granulation processes: Effect of process and formulation parameters Chemical Engineering Science. 107: 76-92. DOI: 10.1016/J.Ces.2013.11.031  0.554
2014 Sen M, Singh R, Ramachandran R. Simulation-based design of an efficient control system for the continuous purification and processing of active pharmaceutical ingredients Journal of Pharmaceutical Innovation. 9: 65-81. DOI: 10.1007/S12247-014-9173-6  0.386
2014 Chaudhury A, Barrasso D, Pandey P, Wu H, Ramachandran R. Population balance model development, validation, and prediction of CQAs of a high-shear wet granulation process: Towards QbD in drug product pharmaceutical manufacturing Journal of Pharmaceutical Innovation. 9: 53-64. DOI: 10.1007/S12247-014-9172-7  0.546
2014 Singh R, Barrasso D, Chaudhury A, Sen M, Ierapetritou M, Ramachandran R. Closed-Loop Feedback Control of a Continuous Pharmaceutical Tablet Manufacturing Process via Wet Granulation Journal of Pharmaceutical Innovation. 9: 16-37. DOI: 10.1007/S12247-014-9170-9  0.448
2013 Kašpar O, Tokárová V, Oka S, Sowrirajan K, Ramachandran R, St?pánek F. Combined UV/Vis and micro-tomography investigation of acetaminophen dissolution from granules. International Journal of Pharmaceutics. PMID 24513549 DOI: 10.1016/J.Ijpharm.2013.10.032  0.342
2013 Singh R, Ierapetritou M, Ramachandran R. System-wide hybrid MPC-PID control of a continuous pharmaceutical tablet manufacturing process via direct compaction. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fã¼R Pharmazeutische Verfahrenstechnik E.V. 85: 1164-82. PMID 23523542 DOI: 10.1016/J.Ejpb.2013.02.019  0.429
2013 Sen M, Chaudhury A, Singh R, John J, Ramachandran R. Multi-scale flowsheet simulation of an integrated continuous purification-downstream pharmaceutical manufacturing process. International Journal of Pharmaceutics. 445: 29-38. PMID 23380627 DOI: 10.1016/J.Ijpharm.2013.01.054  0.486
2013 Pandey P, Tao J, Chaudhury A, Ramachandran R, Gao JZ, Bindra DS. A combined experimental and modeling approach to study the effects of high-shear wet granulation process parameters on granule characteristics. Pharmaceutical Development and Technology. 18: 210-24. PMID 22780851 DOI: 10.3109/10837450.2012.700933  0.538
2013 Sen M, Dubey A, Singh R, Ramachandran R. Mathematical Development and Comparison of a Hybrid PBM-DEM Description of a Continuous Powder Mixing Process Journal of Powder Technology. 2013: 1-11. DOI: 10.1155/2013/843784  0.556
2013 Prakash AV, Chaudhury A, Ramachandran R. Parallel simulation of population balance model-based particulate processes using multicore CPUs and GPUs Modelling and Simulation in Engineering. 2013: 2. DOI: 10.1155/2013/475478  0.458
2013 Chaudhury A, Ramachandran R. Integrated population balance model development and validation of a granulation process Particulate Science and Technology. 31: 407-418. DOI: 10.1080/02726351.2013.767295  0.526
2013 Barrasso D, Walia S, Ramachandran R. Multi-component population balance modeling of continuous granulation processes: A parametric study and comparison with experimental trends Powder Technology. 241: 85-97. DOI: 10.1016/J.Powtec.2013.03.001  0.592
2013 Prakash AV, Chaudhury A, Barrasso D, Ramachandran R. Simulation of population balance model-based particulate processes via parallel and distributed computing Chemical Engineering Research & Design. 91: 1259-1271. DOI: 10.1016/J.Cherd.2013.01.017  0.43
2013 Sen M, Rogers A, Singh R, Chaudhury A, John J, Ierapetritou MG, Ramachandran R. Flowsheet optimization of an integrated continuous purification-processing pharmaceutical manufacturing operation Chemical Engineering Science. 102: 56-66. DOI: 10.1016/J.Ces.2013.07.035  0.495
2013 Chaudhury A, Kapadia A, Prakash AV, Barrasso D, Ramachandran R. An extended cell-average technique for a multi-dimensional population balance of granulation describing aggregation and breakage Advanced Powder Technology. 24: 962-971. DOI: 10.1016/J.Apt.2013.01.006  0.449
2013 Chaudhury A, Niziolek A, Ramachandran R. Multi-dimensional mechanistic modeling of fluid bed granulation processes: An integrated approach Advanced Powder Technology. 24: 113-131. DOI: 10.1016/J.Apt.2012.03.005  0.505
2013 Sen M, Ramachandran R. A multi-dimensional population balance model approach to continuous powder mixing processes Advanced Powder Technology. 24: 51-59. DOI: 10.1016/J.Apt.2012.02.001  0.556
2013 Singh R, Ierapetritou M, Ramachandran R. Hybrid advanced control of flexible multipurpose continuous tablet manufacturing process via direct compaction Computer-Aided Chemical Engineering. 32: 757-762. DOI: 10.1016/B978-0-444-63234-0.50127-5  0.41
2013 Barrasso D, Oka S, Muliadi A, Litster JD, Wassgren C, Ramachandran R. Population balance model validation and predictionof CQAs for Continuous milling processes: Toward QbDin pharmaceutical drug product manufacturing Journal of Pharmaceutical Innovation. 8: 147-162. DOI: 10.1007/S12247-013-9155-0  0.541
2013 Boukouvala F, Chaudhury A, Sen M, Zhou R, Mioduszewski L, Ierapetritou MG, Ramachandran R. Computer-aided flowsheet simulation of a pharmaceutical tablet manufacturing process incorporating wet granulation Journal of Pharmaceutical Innovation. 8: 11-27. DOI: 10.1007/S12247-012-9143-9  0.532
2012 Singh R, Ierapetritou M, Ramachandran R. An engineering study on the enhanced control and operation of continuous manufacturing of pharmaceutical tablets via roller compaction. International Journal of Pharmaceutics. 438: 307-26. PMID 22982489 DOI: 10.1016/J.Ijpharm.2012.09.009  0.408
2012 Boukouvala F, Niotis V, Ramachandran R, Muzzio FJ, Ierapetritou MG. An integrated approach for dynamic flowsheet modeling and sensitivity analysis of a continuous tablet manufacturing process Computers and Chemical Engineering. 42: 30-47. DOI: 10.1016/J.Compchemeng.2012.02.015  0.535
2012 Ramachandran R, Chaudhury A. Model-based design and control of a continuous drum granulation process Chemical Engineering Research and Design. 90: 1063-1073. DOI: 10.1016/J.Cherd.2011.10.022  0.48
2012 Barrasso D, Ramachandran R. A comparison of model order reduction techniques for a four-dimensional population balance model describing multi-component wet granulation processes Chemical Engineering Science. 80: 380-392. DOI: 10.1016/J.Ces.2012.06.039  0.494
2012 Sen M, Singh R, Vanarase A, John J, Ramachandran R. Multi-dimensional population balance modeling and experimental validation of continuous powder mixing processes Chemical Engineering Science. 80: 349-360. DOI: 10.1016/J.Ces.2012.06.024  0.564
2012 Ramachandran R, Ansari MA, Chaudhury A, Kapadia A, Prakash AV, Stepanek F. A quantitative assessment of the influence of primary particle size polydispersity on granule inhomogeneity Chemical Engineering Science. 71: 104-110. DOI: 10.1016/J.Ces.2011.11.045  0.393
2012 Boukouvala F, Dubey A, Vanarase A, Ramachandran R, Muzzio FJ, Ierapetritou M. Computational approaches for studying the granular dynamics of continuous blending processes, 2 - Population balance and data-based methods Macromolecular Materials and Engineering. 297: 9-19. DOI: 10.1002/Mame.201100054  0.504
2011 Schaber SD, Gerogiorgis DI, Ramachandran R, Evans JMB, Barton PI, Trout BL. Economic analysis of integrated continuous and batch pharmaceutical manufacturing: A case study Industrial and Engineering Chemistry Research. 50: 10083-10092. DOI: 10.1021/Ie2006752  0.374
2011 Boukouvala F, Ramachandran R, Vanarase A, Muzzio FJ, Ierapetritou MG. Computer Aided Design and Analysis of Continuous Pharmaceutical Manufacturing Processes Computer Aided Chemical Engineering. 29: 216-220. DOI: 10.1016/B978-0-444-53711-9.50044-4  0.484
2011 Ramachandran R. A Multi-scale Systems Approach to Granulation Process Design Computer Aided Chemical Engineering. 29: 91-95. DOI: 10.1016/B978-0-444-53711-9.50019-5  0.486
2011 Ramachandran R, Arjunan J, Chaudhury A, Ierapetritou MG. Model-based control-loop performance of a continuous direct compaction process Journal of Pharmaceutical Innovation. 6: 249-263. DOI: 10.1007/S12247-011-9118-2  0.457
2010 Ramachandran R, Barton PI. Effective parameter estimation within a multi-dimensional population balance model framework Chemical Engineering Science. 65: 4884-4893. DOI: 10.1016/J.Ces.2010.05.039  0.393
2009 Štěpánek F, Rajniak P, Mancinelli C, Chern RT, Ramachandran R. Distribution and accessibility of binder in wet granules Powder Technology. 189: 376-384. DOI: 10.1016/J.Powtec.2008.04.015  0.401
2009 Glaser T, Sanders CFW, Wang FY, Cameron IT, Litster JD, Poon JMH, Ramachandran R, Immanuel CD, Doyle FJ. Model predictive control of continuous drum granulation Journal of Process Control. 19: 615-622. DOI: 10.1016/J.Jprocont.2008.09.001  0.743
2009 Ramachandran R, Immanuel CD, Stepanek F, Litster JD, Doyle FJ. A mechanistic model for breakage in population balances of granulation: Theoretical kernel development and experimental validation Chemical Engineering Research and Design. 87: 598-614. DOI: 10.1016/J.Cherd.2008.11.007  0.763
2009 Poon JMH, Ramachandran R, Sanders CFW, Glaser T, Immanuel CD, Doyle FJ, Litster JD, Stepanek F, Wang FY, Cameron IT. Experimental validation studies on a multi-dimensional and multi-scale population balance model of batch granulation Chemical Engineering Science. 64: 775-786. DOI: 10.1016/J.Ces.2008.08.037  0.77
2008 Ramachandran R, Poon JMH, Sanders CFW, Glaser T, Immanuel CD, Doyle FJ, Litster JD, Stepanek F, Wang FY, Cameron IT. Experimental studies on distributions of granule size, binder content and porosity in batch drum granulation: Inferences on process modelling requirements and process sensitivities Powder Technology. 188: 89-101. DOI: 10.1016/J.Powtec.2008.04.013  0.763
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