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Whasil Lee, Ph.D. - Publications

Affiliations: 
2018- Biomedical Engineering / Pharmacology and Physiology University of Rochester, Rochester, NY 
Area:
Mechanotransduction, Cell mechanics
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20 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Gao W, Hasan H, Anderson DE, Lee W. The Role of Mechanically-Activated Ion Channels Piezo1, Piezo2, and TRPV4 in Chondrocyte Mechanotransduction and Mechano-Therapeutics for Osteoarthritis. Frontiers in Cell and Developmental Biology. 10: 885224. PMID 35602590 DOI: 10.3389/fcell.2022.885224  0.323
2021 Lee W, Nims RJ, Savadipour A, Zhang Q, Leddy HA, Liu F, McNulty AL, Chen Y, Guilak F, Liedtke WB. Inflammatory signaling sensitizes Piezo1 mechanotransduction in articular chondrocytes as a pathogenic feed-forward mechanism in osteoarthritis. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33758095 DOI: 10.1073/pnas.2001611118  0.724
2017 Lee W, Guilak F, Liedtke W. Role of Piezo Channels in Joint Health and Injury. Current Topics in Membranes. 79: 263-273. PMID 28728820 DOI: 10.1016/Bs.Ctm.2016.10.003  0.683
2016 Kanju P, Chen Y, Lee W, Yeo M, Lee SH, Romac J, Shahid R, Fan P, Gooden DM, Simon SA, Spasojevic I, Mook RA, Liddle RA, Guilak F, Liedtke WB. Small molecule dual-inhibitors of TRPV4 and TRPA1 for attenuation of inflammation and pain. Scientific Reports. 6: 26894. PMID 27247148 DOI: 10.1038/Srep26894  0.637
2016 Lee W, Leddy H, McNulty A, Guilak F, Liedtke W. Inflammatory Cytokine Il-1α Up-Regulates Piezo1 and Hyper-Sensitizes Chondrocytes to Compression Biophysical Journal. 110: 349a. DOI: 10.1016/J.Bpj.2015.11.1878  0.761
2014 Lee W, Leddy HA, Chen Y, Lee SH, Zelenski NA, McNulty AL, Wu J, Beicker KN, Coles J, Zauscher S, Grandl J, Sachs F, Guilak F, Liedtke WB. Synergy between Piezo1 and Piezo2 channels confers high-strain mechanosensitivity to articular cartilage. Proceedings of the National Academy of Sciences of the United States of America. 111: E5114-22. PMID 25385580 DOI: 10.1073/Pnas.1414298111  0.735
2014 Chen Y, Kanju P, Fang Q, Lee SH, Parekh PK, Lee W, Moore C, Brenner D, Gereau RW, Wang F, Liedtke W. TRPV4 is necessary for trigeminal irritant pain and functions as a cellular formalin receptor. Pain. 155: 2662-72. PMID 25281928 DOI: 10.1016/J.Pain.2014.09.033  0.565
2014 Lee W, Leddy H, Guilak F, Liedtke W. Characterization of Mechanotransensitivity of Articular Chondrocytes Biophysical Journal. 106: 389a-390a. DOI: 10.1016/J.Bpj.2013.11.2202  0.759
2012 Lee W, Strümpfer J, Bennett V, Schulten K, Marszalek PE. Mutation of conserved histidines alters tertiary structure and nanomechanics of consensus ankyrin repeats. The Journal of Biological Chemistry. 287: 19115-21. PMID 22514283 DOI: 10.1074/Jbc.M112.365569  0.722
2012 Lee W, Zeng X, Rotolo K, Yang M, Schofield CJ, Bennett V, Yang W, Marszalek PE. Mechanical anisotropy of ankyrin repeats. Biophysical Journal. 102: 1118-26. PMID 22404934 DOI: 10.1016/J.Bpj.2012.01.046  0.719
2012 Lee W, Strümpfer J, Bennett V, Schulten K, Marszalek PE. Mutation of conserved histidines alters tertiary structure and nanomechanics of consensus ankyrin repeats (Journal of Biological Chemistry (2012) 287, (19115-19121) DOI: 10.1074/jbc.A112.365569) Journal of Biological Chemistry. 287: 35539. DOI: 10.1074/Jbc.A112.365569  0.62
2011 Lee W, Zeng X, Zhou H, Bennett V, Yang W, Marszalek P. Full Reconstruction of a Vectorial Protein Folding Pathway by Afm and Smd: Insights Into the Co-Translational Folding of the Nascent-Polypeptide-Chain Biophysical Journal. 100: 483a. DOI: 10.1016/J.Bpj.2010.12.2829  0.702
2010 Lee W, Zeng X, Zhou HX, Bennett V, Yang W, Marszalek PE. Full reconstruction of a vectorial protein folding pathway by atomic force microscopy and molecular dynamics simulations. The Journal of Biological Chemistry. 285: 38167-72. PMID 20870713 DOI: 10.1074/Jbc.M110.179697  0.704
2010 Kim M, Abdi K, Lee G, Rabbi M, Lee W, Yang M, Schofield CJ, Bennett V, Marszalek PE. Fast and forceful refolding of stretched alpha-helical solenoid proteins. Biophysical Journal. 98: 3086-92. PMID 20550922 DOI: 10.1016/J.Bpj.2010.02.054  0.741
2010 Serquera D, Lee W, Settanni G, Marszalek PE, Paci E, Itzhaki LS. Mechanical unfolding of an ankyrin repeat protein. Biophysical Journal. 98: 1294-301. PMID 20371329 DOI: 10.1016/J.Bpj.2009.12.4287  0.672
2010 Kim M, Abdi K, Lee G, Rabbi M, Lee W, Yang M, Schofield CJ, Bennett V, Marszalek PE. Single-Molecule Atomic-Force Spectroscopy Captures a Novel Class of Molecular Nanosprings with Robust Stepwise Refolding Properties Biophysical Journal. 98: 593a-594a. DOI: 10.1016/J.Bpj.2009.12.3230  0.762
2010 Lee W, Yang M, Schofield CJ, Marszalek PE. Nanomechanics of Ankyrin-R Repeats Probed by AFM and SMD Simulations Biophysical Journal. 98: 447a. DOI: 10.1016/J.Bpj.2009.12.2432  0.628
2009 Jiang Y, Rabbi M, Kim M, Ke C, Lee W, Clark RL, Mieczkowski PA, Marszalek PE. UVA generates pyrimidine dimers in DNA directly. Biophysical Journal. 96: 1151-8. PMID 19186150 DOI: 10.1016/J.Bpj.2008.10.030  0.679
2009 Rivera M, Lee W, Marszalek PE, Cole DG, Clark RL. Aligning molecular attachment sites in single molecule force spectroscopy measurements 2008 Proceedings of the Asme International Design Engineering Technical Conferences and Computers and Information in Engineering Conference, Detc 2008. 4: 663-667. DOI: 10.1115/DETC2008-50019  0.56
2008 Rivera M, Lee W, Ke C, Marszalek PE, Cole DG, Clark RL. Minimizing pulling geometry errors in atomic force microscope single molecule force spectroscopy. Biophysical Journal. 95: 3991-8. PMID 18641069 DOI: 10.1529/Biophysj.108.138842  0.616
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