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Wolfgang Liedtke - Publications

Affiliations: 
Duke Medical School, Durham, NC, United States 
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72 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Kuebler W, Jordt SE, Liedtke W. COVID-19: Urgent Reconsideration of Lung Edema as a Preventable Outcome: Inhibition of TRPV4 As a Promising and Feasible Approach. Ssrn. 3558887. PMID 32714108 DOI: 10.2139/ssrn.3558887  0.6
2020 Naik SK, Pattanaik K, Eich J, Sparr V, Hauptmann M, Kalsdorf B, Reiling N, Liedtke W, Kuebler WM, Schaible UE, Sonawane A. Differential Roles of the Calcium Ion Channel TRPV4 in Host Responses to Mycobacterium tuberculosis Early and Late in Infection. Iscience. 23: 101206. PMID 32535021 DOI: 10.1016/j.isci.2020.101206  0.6
2020 Kuebler WM, Jordt SE, Liedtke WB. Urgent reconsideration of lung edema as a preventable outcome in COVID-19: Inhibition of TRPV4 represents a promising and feasible approach. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 32401673 DOI: 10.1152/ajplung.00161.2020  0.6
2019 Xu B, Zhang M, Shi X, Zhang R, Chen D, Chen Y, Wang Z, Qiu Y, Zhang T, Xu K, Zhang X, Liedtke W, Wang R, Fang Q. The multifunctional peptide DN-9 produced peripherally acting antinociception in inflammatory and neuropathic pain via mu and kappa opioid receptors. British Journal of Pharmacology. PMID 31444977 DOI: 10.1111/bph.14848  0.44
2019 Gilchrist CL, Leddy HA, Kaye L, Case ND, Rothenberg KE, Little D, Liedtke W, Hoffman BD, Guilak F. TRPV4-mediated calcium signaling in mesenchymal stem cells regulates aligned collagen matrix formation and vinculin tension. Proceedings of the National Academy of Sciences of the United States of America. PMID 30674675 DOI: 10.1073/pnas.1811095116  0.92
2018 Ciura S, Prager-Khoutorsky M, Thirouin ZS, Wyrosdic JC, Olson JE, Liedtke W, Bourque CW. Trpv4 Mediates Hypotonic Inhibition of Central Osmosensory Neurons via Taurine Gliotransmission. Cell Reports. 23: 2245-2253. PMID 29791836 DOI: 10.1016/j.celrep.2018.04.090  0.44
2018 Mannaa M, Markó L, Balogh A, Vigolo E, N'diaye G, Kaßmann M, Michalick L, Weichelt U, Schmidt-Ott KM, Liedtke WB, Huang Y, Müller DN, Kuebler WM, Gollasch M. Transient Receptor Potential Vanilloid 4 Channel Deficiency Aggravates Tubular Damage after Acute Renal Ischaemia Reperfusion. Scientific Reports. 8: 4878. PMID 29559678 DOI: 10.1038/s41598-018-23165-0  0.6
2018 Rodriguez E, Sakurai K, Xu J, Chen Y, Toda K, Zhao S, Han BX, Ryu D, Yin H, Liedtke W, Wang F. Publisher Correction: A craniofacial-specific monosynaptic circuit enables heightened affective pain. Nature Neuroscience. PMID 29549316 DOI: 10.1038/s41593-018-0103-7  0.4
2017 Moore C, Gupta R, Jordt SE, Chen Y, Liedtke WB. Regulation of Pain and Itch by TRP Channels. Neuroscience Bulletin. PMID 29282613 DOI: 10.1007/s12264-017-0200-8  0.6
2017 Rodriguez E, Sakurai K, Xu J, Chen Y, Toda K, Zhao S, Han BX, Ryu D, Yin H, Liedtke W, Wang F. A craniofacial-specific monosynaptic circuit enables heightened affective pain. Nature Neuroscience. 20: 1734-1743. PMID 29184209 DOI: 10.1038/s41593-017-0012-1  0.4
2017 Chen Y, Moore CD, Zhang JY, Hall RP, MacLeod AS, Liedtke W. TRPV4 Moves toward Center-Fold in Rosacea Pathogenesis. The Journal of Investigative Dermatology. 137: 801-804. PMID 28340683 DOI: 10.1016/j.jid.2016.12.013  0.4
2017 Michalick L, Erfinanda L, Weichelt U, van der Giet M, Liedtke W, Kuebler WM. Transient Receptor Potential Vanilloid 4 and Serum Glucocorticoid-regulated Kinase 1 Are Critical Mediators of Lung Injury in Overventilated Mice In Vivo. Anesthesiology. 126: 300-311. PMID 27861175 DOI: 10.1097/ALN.0000000000001443  0.6
2016 O'Conor CJ, Ramalingam S, Zelenski NA, Benefield HC, Rigo I, Little D, Wu CL, Chen D, Liedtke W, McNulty AL, Guilak F. Cartilage-Specific Knockout of the Mechanosensory Ion Channel TRPV4 Decreases Age-Related Osteoarthritis. Scientific Reports. 6: 29053. PMID 27388701 DOI: 10.1038/srep29053  0.92
2016 Kanju P, Chen Y, Lee W, Yeo M, Lee SH, Romac J, Shahid R, Fan P, Gooden DM, Simon SA, Spasojevic I, Mook RA, Liddle RA, Guilak F, Liedtke WB. Small molecule dual-inhibitors of TRPV4 and TRPA1 for attenuation of inflammation and pain. Scientific Reports. 6: 26894. PMID 27247148 DOI: 10.1038/srep26894  0.92
2016 Chen Y, Fang Q, Wang Z, Zhang JY, MacLeod AS, Hall RP, Liedtke WB. Transient receptor potential vanilloid 4 ion channel functions as a pruriceptor in epidermal keratinocytes to evoke histaminergic itch. The Journal of Biological Chemistry. PMID 26961876 DOI: 10.1074/jbc.M116.716464  0.92
2015 Zaelzer C, Hua P, Prager-Khoutorsky M, Ciura S, Voisin DL, Liedtke W, Bourque CW. ΔN-TRPV1: A Molecular Co-detector of Body Temperature and Osmotic Stress. Cell Reports. 13: 23-30. PMID 26387947 DOI: 10.1016/j.celrep.2015.08.061  0.92
2015 Yin J, Michalick L, Tang C, Tabuchi A, Goldenberg N, Dan Q, Awwad K, Wang L, Erfinanda L, Nouailles-Kursar G, Witzenrath M, Vogelzang A, Lv L, Lee WL, Zhang H, ... ... Liedtke WB, et al. Role of Transient Receptor Potential Vanilloid 4 in Neutrophil Activation and Acute Lung Injury. American Journal of Respiratory Cell and Molecular Biology. PMID 26222277 DOI: 10.1165/rcmb.2014-0225OC  0.92
2015 Cenac N, Bautzova T, Le Faouder P, Veldhuis NA, Poole DP, Rolland C, Bertrand J, Liedtke W, Dubourdeau M, Bertrand-Michel J, Zecchi L, Stanghellini V, Bunnett NW, Barbara G, Vergnolle N. Quantification and Potential Functions of Endogenous Agonists of Transient Receptor Potential Channels in Patients With Irritable Bowel Syndrome. Gastroenterology. 149: 433-44.e7. PMID 25911511 DOI: 10.1053/j.gastro.2015.04.011  0.92
2015 Zhang Y, Chen Y, Liedtke W, Wang F. Lack of evidence for ectopic sprouting of genetically labeled Aβ touch afferents in inflammatory and neuropathic trigeminal pain. Molecular Pain. 11: 18. PMID 25880319 DOI: 10.1186/s12990-015-0017-2  0.4
2015 Zhao P, Lieu T, Barlow N, Sostegni S, Haerteis S, Korbmacher C, Liedtke W, Jimenez-Vargas NN, Vanner SJ, Bunnett NW. Neutrophil Elastase Activates Protease-activated Receptor-2 (PAR2) and Transient Receptor Potential Vanilloid 4 (TRPV4) to Cause Inflammation and Pain. The Journal of Biological Chemistry. 290: 13875-87. PMID 25878251 DOI: 10.1074/jbc.M115.642736  0.92
2015 Goldenberg NM, Wang L, Ranke H, Liedtke W, Tabuchi A, Kuebler WM. TRPV4 Is Required for Hypoxic Pulmonary Vasoconstriction. Anesthesiology. 122: 1338-48. PMID 25815455 DOI: 10.1097/ALN.0000000000000647  0.92
2015 Zelenski NA, Leddy HA, Sanchez-Adams J, Zhang J, Bonaldo P, Liedtke W, Guilak F. Type VI Collagen Regulates Pericellular Matrix Properties, Chondrocyte Swelling, and Mechanotransduction in Mouse Articular Cartilage. Arthritis & Rheumatology (Hoboken, N.J.). 67: 1286-94. PMID 25604429 DOI: 10.1002/art.39034  0.92
2015 McNulty AL, Leddy HA, Liedtke W, Guilak F. TRPV4 as a therapeutic target for joint diseases. Naunyn-Schmiedeberg's Archives of Pharmacology. 388: 437-50. PMID 25519495 DOI: 10.1007/s00210-014-1078-x  0.92
2014 Leddy HA, McNulty AL, Guilak F, Liedtke W. Unraveling the mechanism by which TRPV4 mutations cause skeletal dysplasias. Rare Diseases (Austin, Tex.). 2: e962971. PMID 26942100 DOI: 10.4161/2167549X.2014.962971  0.92
2014 Lee W, Leddy HA, Chen Y, Lee SH, Zelenski NA, McNulty AL, Wu J, Beicker KN, Coles J, Zauscher S, Grandl J, Sachs F, Guilak F, Liedtke WB. Synergy between Piezo1 and Piezo2 channels confers high-strain mechanosensitivity to articular cartilage. Proceedings of the National Academy of Sciences of the United States of America. 111: E5114-22. PMID 25385580 DOI: 10.1073/pnas.1414298111  0.92
2014 Chen Y, Kanju P, Fang Q, Lee SH, Parekh PK, Lee W, Moore C, Brenner D, Gereau RW, Wang F, Liedtke W. TRPV4 is necessary for trigeminal irritant pain and functions as a cellular formalin receptor. Pain. 155: 2662-72. PMID 25281928 DOI: 10.1016/j.pain.2014.09.033  0.92
2014 Lindy AS, Parekh PK, Zhu R, Kanju P, Chintapalli SV, Tsvilovskyy V, Patterson RL, Anishkin A, van Rossum DB, Liedtke WB. TRPV channel-mediated calcium transients in nociceptor neurons are dispensable for avoidance behaviour. Nature Communications. 5: 4734. PMID 25178952 DOI: 10.1038/ncomms5734  0.92
2014 Liedtke W, Zhang JY, Hall RP, Steinhoff M. Keratinocyte growth regulation TRP-ed up over downregulated TRPV4? The Journal of Investigative Dermatology. 134: 2310-2. PMID 25120148 DOI: 10.1038/jid.2014.250  0.92
2014 Zhao P, Lieu T, Barlow N, Metcalf M, Veldhuis NA, Jensen DD, Kocan M, Sostegni S, Haerteis S, Baraznenok V, Henderson I, Lindström E, Guerrero-Alba R, Valdez-Morales EE, Liedtke W, et al. Cathepsin S causes inflammatory pain via biased agonism of PAR2 and TRPV4. The Journal of Biological Chemistry. 289: 27215-34. PMID 25118282 DOI: 10.1074/jbc.M114.599712  0.92
2014 Leddy HA, McNulty AL, Lee SH, Rothfusz NE, Gloss B, Kirby ML, Hutson MR, Cohn DH, Guilak F, Liedtke W. Follistatin in chondrocytes: the link between TRPV4 channelopathies and skeletal malformations. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 2525-37. PMID 24577120 DOI: 10.1096/fj.13-245936  0.92
2014 O'Conor CJ, Leddy HA, Benefield HC, Liedtke WB, Guilak F. TRPV4-mediated mechanotransduction regulates the metabolic response of chondrocytes to dynamic loading. Proceedings of the National Academy of Sciences of the United States of America. 111: 1316-21. PMID 24474754 DOI: 10.1073/pnas.1319569111  0.92
2013 Yeo M, Patisaul H, Liedtke W. Decoding the language of epigenetics during neural development is key for understanding development as well as developmental neurotoxicity. Epigenetics : Official Journal of the Dna Methylation Society. 8: 1128-32. PMID 24071811 DOI: 10.4161/epi.26406  0.92
2013 Moore C, Cevikbas F, Pasolli HA, Chen Y, Kong W, Kempkes C, Parekh P, Lee SH, Kontchou NA, Yeh I, Ye I, Jokerst NM, Fuchs E, Steinhoff M, Liedtke WB. UVB radiation generates sunburn pain and affects skin by activating epidermal TRPV4 ion channels and triggering endothelin-1 signaling. Proceedings of the National Academy of Sciences of the United States of America. 110: E3225-34. PMID 23929777 DOI: 10.1073/pnas.1312933110  0.92
2013 Chen Y, Williams SH, McNulty AL, Hong JH, Lee SH, Rothfusz NE, Parekh PK, Moore C, Gereau RW, Taylor AB, Wang F, Guilak F, Liedtke W. Temporomandibular joint pain: a critical role for Trpv4 in the trigeminal ganglion. Pain. 154: 1295-304. PMID 23726674 DOI: 10.1016/j.pain.2013.04.004  0.92
2013 Dunn KM, Hill-Eubanks DC, Liedtke WB, Nelson MT. TRPV4 channels stimulate Ca2+-induced Ca2+ release in astrocytic endfeet and amplify neurovascular coupling responses. Proceedings of the National Academy of Sciences of the United States of America. 110: 6157-62. PMID 23530219 DOI: 10.1073/pnas.1216514110  0.92
2013 Yeo M, Berglund K, Hanna M, Guo JU, Kittur J, Torres MD, Abramowitz J, Busciglio J, Gao Y, Birnbaumer L, Liedtke WB. Bisphenol A delays the perinatal chloride shift in cortical neurons by epigenetic effects on the Kcc2 promoter. Proceedings of the National Academy of Sciences of the United States of America. 110: 4315-20. PMID 23440186 DOI: 10.1073/pnas.1300959110  0.92
2013 Fariss MW, Gilmour MI, Reilly CA, Liedtke W, Ghio AJ. Emerging mechanistic targets in lung injury induced by combustion-generated particles. Toxicological Sciences : An Official Journal of the Society of Toxicology. 132: 253-67. PMID 23322347 DOI: 10.1093/toxsci/kft001  0.92
2013 Poole DP, Amadesi S, Veldhuis NA, Abogadie FC, Lieu T, Darby W, Liedtke W, Lew MJ, McIntyre P, Bunnett NW. Protease-activated receptor 2 (PAR2) protein and transient receptor potential vanilloid 4 (TRPV4) protein coupling is required for sustained inflammatory signaling. The Journal of Biological Chemistry. 288: 5790-802. PMID 23288842 DOI: 10.1074/jbc.M112.438184  0.92
2013 Liedtke W, Yeo M, Zhang H, Wang Y, Gignac M, Miller S, Berglund K, Liu J. Highly conductive carbon nanotube matrix accelerates developmental chloride extrusion in central nervous system neurons by increased expression of chloride transporter KCC2. Small (Weinheim An Der Bergstrasse, Germany). 9: 1066-75. PMID 23229576 DOI: 10.1002/smll.201201994  0.92
2013 O'Conor CJ, Griffin TM, Liedtke W, Guilak F. Increased susceptibility of Trpv4-deficient mice to obesity and obesity-induced osteoarthritis with very high-fat diet. Annals of the Rheumatic Diseases. 72: 300-4. PMID 23178209 DOI: 10.1136/annrheumdis-2012-202272  0.92
2012 Ye L, Kleiner S, Wu J, Sah R, Gupta RK, Banks AS, Cohen P, Khandekar MJ, Boström P, Mepani RJ, Laznik D, Kamenecka TM, Song X, Liedtke W, Mootha VK, et al. TRPV4 is a regulator of adipose oxidative metabolism, inflammation, and energy homeostasis. Cell. 151: 96-110. PMID 23021218 DOI: 10.1016/j.cell.2012.08.034  0.92
2012 Sonkusare SK, Bonev AD, Ledoux J, Liedtke W, Kotlikoff MI, Heppner TJ, Hill-Eubanks DC, Nelson MT. Elementary Ca2+ signals through endothelial TRPV4 channels regulate vascular function. Science (New York, N.Y.). 336: 597-601. PMID 22556255 DOI: 10.1126/science.1216283  0.92
2012 Bourque CW, Guilak F, Liedtke W. A TRP that makes us feel hyper. The Journal of Physiology. 590: 1779-80. PMID 22532645 DOI: 10.1113/jphysiol.2012.229187  0.92
2011 Ciura S, Liedtke W, Bourque CW. Hypertonicity sensing in organum vasculosum lamina terminalis neurons: a mechanical process involving TRPV1 but not TRPV4. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 14669-76. PMID 21994383 DOI: 10.1523/JNEUROSCI.1420-11.2011  0.92
2011 Liedtke WB, McKinley MJ, Walker LL, Zhang H, Pfenning AR, Drago J, Hochendoner SJ, Hilton DL, Lawrence AJ, Denton DA. Relation of addiction genes to hypothalamic gene changes subserving genesis and gratification of a classic instinct, sodium appetite. Proceedings of the National Academy of Sciences of the United States of America. 108: 12509-14. PMID 21746918 DOI: 10.1073/pnas.1109199108  0.92
2011 Ryskamp DA, Witkovsky P, Barabas P, Huang W, Koehler C, Akimov NP, Lee SH, Chauhan S, Xing W, Rentería RC, Liedtke W, Krizaj D. The polymodal ion channel transient receptor potential vanilloid 4 modulates calcium flux, spiking rate, and apoptosis of mouse retinal ganglion cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 7089-101. PMID 21562271 DOI: 10.1523/JNEUROSCI.0359-11.2011  0.92
2011 Li J, Kanju P, Patterson M, Chew WL, Cho SH, Gilmour I, Oliver T, Yasuda R, Ghio A, Simon SA, Liedtke W. TRPV4-mediated calcium influx into human bronchial epithelia upon exposure to diesel exhaust particles. Environmental Health Perspectives. 119: 784-93. PMID 21245013 DOI: 10.1289/ehp.1002807  0.92
2010 Shukla AK, Kim J, Ahn S, Xiao K, Shenoy SK, Liedtke W, Lefkowitz RJ. Arresting a transient receptor potential (TRP) channel: beta-arrestin 1 mediates ubiquitination and functional down-regulation of TRPV4. The Journal of Biological Chemistry. 285: 30115-25. PMID 20650893 DOI: 10.1074/jbc.M110.141549  0.92
2010 Clark AL, Votta BJ, Kumar S, Liedtke W, Guilak F. Chondroprotective role of the osmotically sensitive ion channel transient receptor potential vanilloid 4: age- and sex-dependent progression of osteoarthritis in Trpv4-deficient mice. Arthritis and Rheumatism. 62: 2973-83. PMID 20583100 DOI: 10.1002/art.27624  0.92
2010 Hamanaka K, Jian MY, Townsley MI, King JA, Liedtke W, Weber DS, Eyal FG, Clapp MM, Parker JC. TRPV4 channels augment macrophage activation and ventilator-induced lung injury. American Journal of Physiology. Lung Cellular and Molecular Physiology. 299: L353-62. PMID 20562229 DOI: 10.1152/ajplung.00315.2009  0.92
2010 Ceppa E, Cattaruzza F, Lyo V, Amadesi S, Pelayo JC, Poole DP, Vaksman N, Liedtke W, Cohen DM, Grady EF, Bunnett NW, Kirkwood KS. Transient receptor potential ion channels V4 and A1 contribute to pancreatitis pain in mice. American Journal of Physiology. Gastrointestinal and Liver Physiology. 299: G556-71. PMID 20539005 DOI: 10.1152/ajpgi.00433.2009  0.4
2010 Guilak F, Leddy HA, Liedtke W. Transient receptor potential vanilloid 4: The sixth sense of the musculoskeletal system? Annals of the New York Academy of Sciences. 1192: 404-9. PMID 20392266 DOI: 10.1111/j.1749-6632.2010.05389.x  0.92
2009 Yeo M, Berglund K, Augustine G, Liedtke W. Novel repression of Kcc2 transcription by REST-RE-1 controls developmental switch in neuronal chloride. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 14652-62. PMID 19923298 DOI: 10.1523/JNEUROSCI.2934-09.2009  0.92
2009 Phan MN, Leddy HA, Votta BJ, Kumar S, Levy DS, Lipshutz DB, Lee SH, Liedtke W, Guilak F. Functional characterization of TRPV4 as an osmotically sensitive ion channel in porcine articular chondrocytes. Arthritis and Rheumatism. 60: 3028-37. PMID 19790068 DOI: 10.1002/art.24799  0.92
2009 Earley S, Pauyo T, Drapp R, Tavares MJ, Liedtke W, Brayden JE. TRPV4-dependent dilation of peripheral resistance arteries influences arterial pressure. American Journal of Physiology. Heart and Circulatory Physiology. 297: H1096-102. PMID 19617407 DOI: 10.1152/ajpheart.00241.2009  0.92
2009 Guilak F, Cohen DM, Estes BT, Gimble JM, Liedtke W, Chen CS. Control of stem cell fate by physical interactions with the extracellular matrix. Cell Stem Cell. 5: 17-26. PMID 19570510 DOI: 10.1016/j.stem.2009.06.016  0.92
2009 Li J, Ghio AJ, Cho SH, Brinckerhoff CE, Simon SA, Liedtke W. Diesel exhaust particles activate the matrix-metalloproteinase-1 gene in human bronchial epithelia in a beta-arrestin-dependent manner via activation of RAS. Environmental Health Perspectives. 117: 400-9. PMID 19337515 DOI: 10.1289/ehp.0800311  0.92
2008 Lorenzo IM, Liedtke W, Sanderson MJ, Valverde MA. TRPV4 channel participates in receptor-operated calcium entry and ciliary beat frequency regulation in mouse airway epithelial cells. Proceedings of the National Academy of Sciences of the United States of America. 105: 12611-6. PMID 18719094 DOI: 10.1073/pnas.0803970105  0.92
2008 Simon SA, Liedtke W. How irritating: the role of TRPA1 in sensing cigarette smoke and aerogenic oxidants in the airways. The Journal of Clinical Investigation. 118: 2383-6. PMID 18568080 DOI: 10.1172/JCI36111  0.92
2008 Cenac N, Altier C, Chapman K, Liedtke W, Zamponi G, Vergnolle N. Transient Receptor Potential Vanilloid-4 Has a Major Role in Visceral Hypersensitivity Symptoms Gastroenterology. 135. PMID 18565335 DOI: 10.1053/j.gastro.2008.05.024  0.92
2008 Brierley SM, Page AJ, Hughes PA, Adam B, Liebregts T, Cooper NJ, Holtmann G, Liedtke W, Blackshaw LA. Selective role for TRPV4 ion channels in visceral sensory pathways. Gastroenterology. 134: 2059-69. PMID 18343379 DOI: 10.1053/j.gastro.2008.01.074  0.92
2008 Sipe WE, Brierley SM, Martin CM, Phillis BD, Cruz FB, Grady EF, Liedtke W, Cohen DM, Vanner S, Blackshaw LA, Bunnett NW. Transient receptor potential vanilloid 4 mediates protease activated receptor 2-induced sensitization of colonic afferent nerves and visceral hyperalgesia. American Journal of Physiology. Gastrointestinal and Liver Physiology. 294: G1288-98. PMID 18325985 DOI: 10.1152/ajpgi.00002.2008  0.92
2008 Yin J, Hoffmann J, Kaestle SM, Neye N, Wang L, Baeurle J, Liedtke W, Wu S, Kuppe H, Pries AR, Kuebler WM. Negative-feedback loop attenuates hydrostatic lung edema via a cGMP-dependent regulation of transient receptor potential vanilloid 4. Circulation Research. 102: 966-74. PMID 18323527 DOI: 10.1161/CIRCRESAHA.107.168724  0.6
2007 Gevaert T, Vriens J, Segal A, Everaerts W, Roskams T, Talavera K, Owsianik G, Liedtke W, Daelemans D, Dewachter I, Van Leuven F, Voets T, De Ridder D, Nilius B. Deletion of the transient receptor potential cation channel TRPV4 impairs murine bladder voiding. The Journal of Clinical Investigation. 117: 3453-62. PMID 17948126 DOI: 10.1172/JCI31766  0.92
2007 Liu L, Chen L, Liedtke W, Simon SA. Changes in osmolality sensitize the response to capsaicin in trigeminal sensory neurons Journal of Neurophysiology. 97: 2001-2015. PMID 17353553 DOI: 10.1152/jn.00887.2006  0.92
2007 Grant AD, Cottrell GS, Amadesi S, Trevisani M, Nicoletti P, Materazzi S, Altier C, Cenac N, Zamponi GW, Bautista-Cruz F, Lopez CB, Joseph EK, Levine JD, Liedtke W, Vanner S, et al. Protease-activated receptor 2 sensitizes the transient receptor potential vanilloid 4 ion channel to cause mechanical hyperalgesia in mice. The Journal of Physiology. 578: 715-33. PMID 17124270 DOI: 10.1113/jphysiol.2006.121111  0.92
2006 Liu X, Bandyopadhyay BC, Bandyopadhyay B, Nakamoto T, Singh B, Liedtke W, Melvin JE, Ambudkar I. A role for AQP5 in activation of TRPV4 by hypotonicity: concerted involvement of AQP5 and TRPV4 in regulation of cell volume recovery. The Journal of Biological Chemistry. 281: 15485-95. PMID 16571723 DOI: 10.1074/jbc.M600549200  0.4
2006 Liu L, Yang TM, Liedtke W, Simon SA. Chronic IL-1β signaling potentiates voltage-dependent sodium currents in trigeminal nociceptive neurons Journal of Neurophysiology. 95: 1478-1490. PMID 16319216 DOI: 10.1152/jn.00509.2005  0.92
2004 Liedtke W, Simon SA. A possible role for TRPV4 receptors in asthma American Journal of Physiology - Lung Cellular and Molecular Physiology. 287: L269-L271. PMID 15246981 DOI: 10.1152/ajplung.00153.2004  0.92
2003 Liedtke W, Tobin DM, Bargmann CI, Friedman JM. Mammalian TRPV4 (VR-OAC) directs behavioral responses to osmotic and mechanical stimuli in Caenorhabditis elegans. Proceedings of the National Academy of Sciences of the United States of America. 100: 14531-6. PMID 14581619 DOI: 10.1073/pnas.2235619100  0.92
2003 Liedtke W, Friedman JM. Abnormal osmotic regulation in trpv4-/- mice. Proceedings of the National Academy of Sciences of the United States of America. 100: 13698-703. PMID 14581612 DOI: 10.1073/pnas.1735416100  0.92
2002 Cohen P, Miyazaki M, Socci ND, Hagge-Greenberg A, Liedtke W, Soukas AA, Sharma R, Hudgins LC, Ntambi JM, Friedman JM. Role for stearoyl-CoA desaturase-1 in leptin-mediated weight loss. Science (New York, N.Y.). 297: 240-3. PMID 12114623 DOI: 10.1126/science.1071527  0.92
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