☰

James R. Horn - Publications

Affiliations: 
2006- Chemistry and Biochemistry Northern Illinois University, DeKalb, IL, United States 
Area:
Protein Interactions; Protein Engineering
Website:
http://hornlab.niu.edu
Tree Info Similar researchers PubMed Report error

30 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Smith CA, Sonneson GJ, Hoey RJ, Hinerman JM, Sheehy K, Walter R, Herr AB, Horn JR. Molecular recognition requires dimerization of a VHH antibody. Mabs. 15: 2215363. PMID 37243579 DOI: 10.1080/19420862.2023.2215363  0.382
2022 Laughlin TM, Horn JR. Engineering pH-Sensitive Single-Domain Antibodies. Methods in Molecular Biology (Clifton, N.J.). 2446: 269-298. PMID 35157278 DOI: 10.1007/978-1-0716-2075-5_13  0.462
2021 Blain JM, Grote DL, Watkins SM, Goshu GM, Muller C, Gorman JL, Ranieri G, Walter RL, Hofstetter H, Horn JR, Hagen TJ. Structural and biophysical characterization of the Burkholderia pseudomallei IspF inhibitor L-tryptophan hydroxamate. Bioorganic & Medicinal Chemistry Letters. 48: 128273. PMID 34298132 DOI: 10.1016/j.bmcl.2021.128273  0.342
2019 Hoey RJ, Eom H, Horn JR. Structure and development of single domain antibodies as modules for therapeutics and diagnostics. Experimental Biology and Medicine (Maywood, N.J.). 1535370219881129. PMID 31594404 DOI: 10.1177/1535370219881129  0.392
2019 Watkins SM, Ghose D, Blain JM, Grote DL, Luan CH, Clare M, Meganathan R, Horn JR, Hagen TJ. Antibacterial activity of 2-amino-4-hydroxypyrimidine-5-carboxylates and binding to Burkholderia pseudomallei 2-C-methyl-d-erythritol-2,4-cyclodiphosphate synthase. Bioorganic & Medicinal Chemistry Letters. 126660. PMID 31521478 DOI: 10.1016/J.Bmcl.2019.126660  0.411
2018 Kossiakoff AA, Mukherjee S, Horn JR. Reply to Kang and Brooks: Comment on the calculations in protein thermodynamics. The Journal of Biological Chemistry. 293: 5063. PMID 29626107 DOI: 10.1074/Jbc.Rl118.002471  0.613
2018 Helgren TR, Seven ES, Chen C, Edwards TE, Staker BL, Abendroth J, Myler PJ, Horn JR, Hagen TJ. The identification of inhibitory compounds of Rickettsia prowazekii methionine aminopeptidase for antibacterial applications. Bioorganic & Medicinal Chemistry Letters. PMID 29551481 DOI: 10.1016/J.Bmcl.2018.03.002  0.348
2018 Mukherjee S, Griffin DH, Horn JR, Rizk SS, Nocula-Lugowska M, Malmqvist M, Kim SS, Kossiakoff AA. Engineered synthetic antibodies as probes to quantify the energetic contributions of ligand binding to conformational changes in proteins. The Journal of Biological Chemistry. PMID 29321208 DOI: 10.1074/Jbc.Ra117.000656  0.818
2016 Davenport KR, Smith CA, Hofstetter H, Horn JR, Hofstetter O. Site-directed immobilization of a genetically engineered anti-methotrexate antibody via an enzymatically introduced biotin label significantly increases the binding capacity of immunoaffinity columns. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. PMID 26809205 DOI: 10.1016/J.Jchromb.2016.01.021  0.469
2015 Horn JR, Murtaugh ML, Fanning SW, Smith CA, Griffin DH. Remodeling Protein Interfaces to Regulate Recognition Biophysical Journal. 108: 627a-628a. DOI: 10.1016/J.Bpj.2014.11.3412  0.726
2014 Fanning SW, Walter R, Horn JR, Tawfik D. Structural basis of an engineered dual-specific antibody: Conformational diversity leads to a hypervariable loop metal-binding site Protein Engineering, Design and Selection. 27: 391-397. PMID 25143596 DOI: 10.1093/Protein/Gzu033  0.783
2013 Zhang Z, Jakkaraju S, Blain J, Gogol K, Zhao L, Hartley RC, Karlsson CA, Staker BL, Edwards TE, Stewart LJ, Myler PJ, Clare M, Begley DW, Horn JR, Hagen TJ. Cytidine derivatives as IspF inhibitors of Burkolderia pseudomallei. Bioorganic & Medicinal Chemistry Letters. 23: 6860-3. PMID 24157367 DOI: 10.1016/J.Bmcl.2013.09.101  0.441
2012 Sztuba-Solińska J, Fanning SW, Horn JR, Bujarski JJ. Mutations in the coat protein-binding cis-acting RNA motifs debilitate RNA recombination of Brome mosaic virus. Virus Research. 170: 138-49. PMID 23079110 DOI: 10.1016/J.Virusres.2012.10.001  0.67
2011 Murtaugh ML, Fanning SW, Sharma TM, Terry AM, Horn JR. A combinatorial histidine scanning library approach to engineer highly pH-dependent protein switches. Protein Science : a Publication of the Protein Society. 20: 1619-31. PMID 21766385 DOI: 10.1002/Pro.696  0.727
2011 Fanning SW, Murtaugh ML, Horn JR. A combinatorial approach to engineering a dual-specific metal switch antibody. Biochemistry. 50: 5093-5. PMID 21568282 DOI: 10.1021/Bi2003845  0.711
2011 Fanning SW, Horn JR. An anti-hapten camelid antibody reveals a cryptic binding site with significant energetic contributions from a nonhypervariable loop. Protein Science : a Publication of the Protein Society. 20: 1196-207. PMID 21557375 DOI: 10.1002/Pro.648  0.77
2011 Fanning SW, Horn JR. An anti-hapten camelid antibody reveals a cryptic binding site with significant energetic contributions from a nonhypervariable loop. Protein Science : a Publication of the Protein Society. 20: 1196-207. PMID 21557375 DOI: 10.1002/pro.648  0.479
2010 Franco EJ, Sonneson GJ, DeLegge TJ, Hofstetter H, Horn JR, Hofstetter O. Production and characterization of a genetically engineered anti-caffeine camelid antibody and its use in immunoaffinity chromatography. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 878: 177-86. PMID 19560409 DOI: 10.1016/J.Jchromb.2009.06.017  0.332
2010 Franco EJ, Sonneson GJ, DeLegge TJ, Hofstetter H, Horn JR, Hofstetter O. Production and characterization of a genetically engineered anti-caffeine camelid antibody and its use in immunoaffinity chromatography. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 878: 177-86. PMID 19560409 DOI: 10.1016/J.Jchromb.2009.06.017  0.332
2009 Sonneson GJ, Horn JR. Hapten-induced dimerization of a single-domain VHH camelid antibody. Biochemistry. 48: 6693-5. PMID 19572722 DOI: 10.1021/bi900862r  0.443
2009 Sonneson GJ, Horn JR. Hapten-induced dimerization of a single-domain VHH camelid antibody. Biochemistry. 48: 6693-5. PMID 19572722 DOI: 10.1021/Bi900862R  0.531
2009 Horn JR, Sosnick TR, Kossiakoff AA. Principal determinants leading to transition state formation of a protein-protein complex, orientation trumps side-chain interactions. Proceedings of the National Academy of Sciences of the United States of America. 106: 2559-64. PMID 19196954 DOI: 10.1073/Pnas.0809800106  0.71
2009 Rich RL, Papalia GA, Flynn PJ, Furneisen J, Quinn J, Klein JS, Katsamba PS, Waddell MB, Scott M, Thompson J, Berlier J, Corry S, Baltzinger M, Zeder-Lutz G, Schoenemann A, ... ... Horn J, et al. A global benchmark study using affinity-based biosensors. Analytical Biochemistry. 386: 194-216. PMID 19133223 DOI: 10.1016/J.Ab.2008.11.021  0.489
2006 Horn JR, Kraybill B, Petro EJ, Coales SJ, Morrow JA, Hamuro Y, Kossiakoff AA. The role of protein dynamics in increasing binding affinity for an engineered protein-protein interaction established by H/D exchange mass spectrometry. Biochemistry. 45: 8488-98. PMID 16834322 DOI: 10.1021/Bi0604328  0.724
2005 Kouadio JL, Horn JR, Pal G, Kossiakoff AA. Shotgun alanine scanning shows that growth hormone can bind productively to its receptor through a drastically minimized interface. The Journal of Biological Chemistry. 280: 25524-32. PMID 15857837 DOI: 10.1074/Jbc.M502167200  0.7
2004 Horn JR, Shoichet BK. Allosteric inhibition through core disruption. Journal of Molecular Biology. 336: 1283-91. PMID 15037085 DOI: 10.1016/J.Jmb.2003.12.068  0.664
2003 Horn JR, Ramaswamy S, Murphy KP. Structure and energetics of protein-protein interactions: the role of conformational heterogeneity in OMTKY3 binding to serine proteases. Journal of Molecular Biology. 331: 497-508. PMID 12888355 DOI: 10.1016/S0022-2836(03)00783-6  0.74
2002 Horn JR, Brandts JF, Murphy KP. van't Hoff and calorimetric enthalpies II: effects of linked equilibria. Biochemistry. 41: 7501-7. PMID 12044184 DOI: 10.1021/Bi025626B  0.601
2001 Horn JR, Russell D, Lewis EA, Murphy KP. Van't Hoff and calorimetric enthalpies from isothermal titration calorimetry: are there significant discrepancies? Biochemistry. 40: 1774-8. PMID 11327839 DOI: 10.1021/Bi002408E  0.669
1999 Murphy KP, Baker BM, Edgcomb SP, Horn JR. Structural energetics of serine protease inhibition Pure and Applied Chemistry. 71: 1207-1213. DOI: 10.1351/Pac199971071207  0.77
Show low-probability matches.