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Daniel Shiu-Hin Chan, Ph.D. - Publications

Affiliations: 
2010-2013 Chemistry Hong Kong Baptist University 
 2014-2018 Chemistry University of Cambridge, Cambridge, England, United Kingdom 
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64 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Trapero A, Pacitto A, Chan DS, Abell C, Blundell TL, Ascher DB, Coyne AG. Covalent inactivation of Mycobacterium thermoresistibile inosine-5'-monophosphate dehydrogenase (IMPDH). Bioorganic & Medicinal Chemistry Letters. 126792. PMID 31757668 DOI: 10.1016/J.Bmcl.2019.126792  0.667
2019 Chan DS, Hess J, Shaw E, Spry C, Starley R, Dagostin C, Dias MV, Kale R, Mendes V, Blundell TL, Coyne AG, Abell C. Structural Insights into Phosphopantothenoylcysteine Synthetase by Native Ion Mobility-Mass Spectrometry. The Biochemical Journal. PMID 31488574 DOI: 10.1042/Bcj20190318  0.683
2017 Chan DS, Whitehouse AJ, Coyne AG, Abell C. Mass spectrometry for fragment screening. Essays in Biochemistry. PMID 28986384 DOI: 10.1042/Ebc20170071  0.684
2017 Chan DS, Mendes V, Thomas SE, McConnell BN, Matak-Vinković D, Coyne AG, Blundell TL, Abell C. Fragment screening against the EthR-DNA interaction by native mass spectrometry. Angewandte Chemie (International Ed. in English). PMID 28513917 DOI: 10.1002/Anie.201702888  0.683
2016 Seetoh WG, Chan DS, Matak-Vinković D, Abell C. Mass Spectrometry Reveals Protein Kinase CK2 High-Order Oligomerization via the Circular and Linear Assembly. Acs Chemical Biology. 11: 1511-7. PMID 26999075 DOI: 10.1021/Acschembio.6B00064  0.426
2015 Ma DL, Chan DS, Wei G, Zhong HJ, Yang H, Leung LT, Gullen EA, Chiu P, Cheng YC, Leung CH. Correction: Virtual screening and optimization of Type II inhibitors of JAK2 from a natural product library. Chemical Communications (Cambridge, England). 51: 959. PMID 25429723 DOI: 10.1039/C4Cc90479F  0.441
2015 Liu LJ, Leung KH, Lin S, Chan DS, Susanti D, Rao W, Chan PW, Ma DL, Leung CH. Pharmacophore modeling for the identification of small-molecule inhibitors of TACE. Methods (San Diego, Calif.). 71: 92-7. PMID 25260600 DOI: 10.1016/j.ymeth.2014.09.005  0.487
2015 Zhong HJ, Leung KH, Lin S, Chan DS, Han QB, Chan SL, Ma DL, Leung CH. Discovery of deoxyvasicinone derivatives as inhibitors of NEDD8-activating enzyme. Methods (San Diego, Calif.). 71: 71-6. PMID 25196325 DOI: 10.1016/j.ymeth.2014.08.014  0.517
2015 Leung KH, Liu LJ, Lin S, Lu L, Zhong HJ, Susanti D, Rao W, Wang M, Che WI, Chan DS, Leung CH, Chan PW, Ma DL. Discovery of a small-molecule inhibitor of STAT3 by ligand-based pharmacophore screening. Methods (San Diego, Calif.). 71: 38-43. PMID 25160651 DOI: 10.1016/J.Ymeth.2014.07.010  0.503
2015 Zhong HJ, Lin S, Tam IL, Lu L, Chan DS, Ma DL, Leung CH. In silico identification of natural product inhibitors of JAK2. Methods (San Diego, Calif.). 71: 21-5. PMID 25038528 DOI: 10.1016/J.Ymeth.2014.07.003  0.513
2014 Wang M, Leung KH, Lin S, Chan DS, Leung CH, Ma DL. A G-quadruplex-based, label-free, switch-on luminescent detection assay for Ag ions based on the exonuclease III-mediated digestion of C-Ag-C DNA. Journal of Materials Chemistry. B. 2: 6467-6471. PMID 32261807 DOI: 10.1039/C4Tb01140F  0.511
2014 Zhong HJ, Leung KH, Liu LJ, Lu L, Chan DS, Leung CH, Ma DL. Antagonism of mTOR Activity by a Kinetically Inert Rhodium(III) Complex. Chempluschem. 79: 508-511. PMID 31986693 DOI: 10.1002/Cplu.201400014  0.51
2014 Wong CY, Chung LH, Lin S, Chan DS, Leung CH, Ma DL. A ruthenium(II) complex supported by trithiacyclononane and aromatic diimine ligand as luminescent switch-on probe for biomolecule detection and protein staining. Scientific Reports. 4: 7136. PMID 25409703 DOI: 10.1038/srep07136  0.488
2014 Ma DL, Chan DS, Leung CH. Group 9 organometallic compounds for therapeutic and bioanalytical applications. Accounts of Chemical Research. 47: 3614-31. PMID 25369127 DOI: 10.1021/Ar500310Z  0.542
2014 Wang M, Leung KH, Lin S, Chan DS, Kwong DW, Leung CH, Ma DL. A colorimetric chemosensor for Cu²⁺ ion detection based on an iridium(III) complex. Scientific Reports. 4: 6794. PMID 25348724 DOI: 10.1038/Srep06794  0.481
2014 Ma DL, Chan DS, Wei G, Zhong HJ, Yang H, Leung LT, Gullen EA, Chiu P, Cheng YC, Leung CH. Virtual screening and optimization of Type II inhibitors of JAK2 from a natural product library. Chemical Communications (Cambridge, England). 50: 13885-8. PMID 25225654 DOI: 10.1039/C4Cc04498C  0.482
2014 Ma DL, He HZ, Zhong HJ, Lin S, Chan DS, Wang L, Lee SM, Leung CH, Wong CY. Visualization of Zn²⁺ ions in live zebrafish using a luminescent iridium(III) chemosensor. Acs Applied Materials & Interfaces. 6: 14008-15. PMID 25051997 DOI: 10.1021/Am504369B  0.478
2014 Liu LJ, Lin S, Chan DS, Vong CT, Hoi PM, Wong CY, Ma DL, Leung CH. A rhodium(III) complex inhibits LPS-induced nitric oxide production and angiogenic activity in cellulo. Journal of Inorganic Biochemistry. 140: 23-8. PMID 25046384 DOI: 10.1016/J.Jinorgbio.2014.06.020  0.475
2014 Ma DL, He HZ, Chan DS, Wong CY, Leung CH. A colorimetric and luminescent dual-modal assay for Cu(II) ion detection using an iridium(III) complex. Plos One. 9: e99930. PMID 24927177 DOI: 10.1371/Journal.Pone.0099930  0.483
2014 Ma DL, Liu LJ, Leung KH, Chen YT, Zhong HJ, Chan DS, Wang HM, Leung CH. Antagonizing STAT3 dimerization with a rhodium(III) complex. Angewandte Chemie (International Ed. in English). 53: 9178-82. PMID 24889897 DOI: 10.1002/Anie.201404686  0.493
2014 Ma DL, Lin S, Leung KH, Zhong HJ, Liu LJ, Chan DS, Bourdoncle A, Mergny JL, Wang HM, Leung CH. An oligonucleotide-based label-free luminescent switch-on probe for RNA detection utilizing a G-quadruplex-selective iridium(III) complex. Nanoscale. 6: 8489-94. PMID 24816304 DOI: 10.1039/C4Nr00541D  0.514
2014 Zhong HJ, Liu LJ, Chong CM, Lu L, Wang M, Chan DS, Chan PW, Lee SM, Ma DL, Leung CH. Discovery of a natural product-like iNOS inhibitor by molecular docking with potential neuroprotective effects in vivo. Plos One. 9: e92905. PMID 24690920 DOI: 10.1371/Journal.Pone.0092905  0.471
2014 Zhong HJ, Liu LJ, Chan DS, Wang HM, Chan PW, Ma DL, Leung CH. Structure-based repurposing of FDA-approved drugs as inhibitors of NEDD8-activating enzyme. Biochimie. 102: 211-5. PMID 24657219 DOI: 10.1016/j.biochi.2014.03.005  0.519
2014 He HZ, Leung KH, Wang W, Chan DS, Leung CH, Ma DL. Label-free luminescence switch-on detection of T4 polynucleotide kinase activity using a G-quadruplex-selective probe. Chemical Communications (Cambridge, England). 50: 5313-5. PMID 24336506 DOI: 10.1039/C3Cc47444E  0.534
2013 Leung KH, He HZ, Wang W, Zhong HJ, Chan DS, Leung CH, Ma DL. Label-free luminescent switch-on detection of endonuclease IV activity using a G-quadruplex-selective iridium(III) complex. Acs Applied Materials & Interfaces. 5: 12249-53. PMID 24245499 DOI: 10.1021/Am404314P  0.542
2013 Leung KH, Lu L, Wang M, Mak TY, Chan DS, Tang FK, Leung CH, Kwan HY, Yu Z, Ma DL. A label-free luminescent switch-on assay for ATP using a G-quadruplex-selective iridium(III) complex. Plos One. 8: e77021. PMID 24204723 DOI: 10.1371/Journal.Pone.0077021  0.535
2013 He HZ, Chan WI, Mak TY, Liu LJ, Wang M, Chan DS, Ma DL, Leung CH. Detection of 3'→5' exonuclease activity using a metal-based luminescent switch-on probe. Methods (San Diego, Calif.). 64: 218-23. PMID 23973810 DOI: 10.1016/J.Ymeth.2013.08.011  0.557
2013 He HZ, Wang M, Chan DS, Leung CH, Qiu JW, Ma DL. A label-free G-quadruplex-based luminescent switch-on assay for the selective detection of histidine. Methods (San Diego, Calif.). 64: 205-11. PMID 23891801 DOI: 10.1016/J.Ymeth.2013.07.023  0.541
2013 He HZ, Wang M, Chan DS, Leung CH, Lin X, Lin JM, Ma DL. A parallel G-quadruplex-selective luminescent probe for the detection of nanomolar calcium(II) ion. Methods (San Diego, Calif.). 64: 212-7. PMID 23876936 DOI: 10.1016/J.Ymeth.2013.07.021  0.514
2013 Ma DL, He HZ, Leung KH, Chan DS, Leung CH. Bioactive luminescent transition-metal complexes for biomedical applications. Angewandte Chemie (International Ed. in English). 52: 7666-82. PMID 23765907 DOI: 10.1002/Anie.201208414  0.487
2013 Leung KH, He HZ, Zhong HJ, Lu L, Chan DS, Ma DL, Leung CH. A highly sensitive G-quadruplex-based luminescent switch-on probe for the detection of polymerase 3'-5' proofreading activity. Methods (San Diego, Calif.). 64: 224-8. PMID 23748144 DOI: 10.1016/J.Ymeth.2013.05.017  0.545
2013 Leung KH, He HZ, Ma VP, Zhong HJ, Chan DS, Zhou J, Mergny JL, Leung CH, Ma DL. Detection of base excision repair enzyme activity using a luminescent G-quadruplex selective switch-on probe. Chemical Communications (Cambridge, England). 49: 5630-2. PMID 23559154 DOI: 10.1039/C3Cc41129J  0.557
2013 Chan DS, Fu WC, Wang M, Liu LJ, Leung CH, Ma DL. A highly selective and non-reaction based chemosensor for the detection of Hg2+ ions using a luminescent iridium(III) complex. Plos One. 8: e60114. PMID 23533670 DOI: 10.1371/Journal.Pone.0060114  0.491
2013 Ma DL, Zhong HJ, Fu WC, Chan DS, Kwan HY, Fong WF, Chung LH, Wong CY, Leung CH. Phosphorescent imaging of living cells using a cyclometalated iridium (III) complex. Plos One. 8: e55751. PMID 23457478 DOI: 10.1371/Journal.Pone.0055751  0.435
2013 He HZ, Chan DS, Leung CH, Ma DL. G-quadruplexes for luminescent sensing and logic gates. Nucleic Acids Research. 41: 4345-59. PMID 23435319 DOI: 10.1093/Nar/Gkt108  0.526
2013 Leung CH, Zhong HJ, Lu L, Chan DS, Ma DL. Luminescent and colorimetric strategies for the label-free DNA-based detection of enzyme activity. Briefings in Functional Genomics. 12: 525-35. PMID 23396725 DOI: 10.1093/bfgp/elt004  0.504
2013 Ma DL, He HZ, Leung KH, Zhong HJ, Chan DS, Leung CH. Label-free luminescent oligonucleotide-based probes. Chemical Society Reviews. 42: 3427-40. PMID 23348604 DOI: 10.1039/C2Cs35472A  0.511
2013 Leung CH, Chan DS, Li YW, Fong WF, Ma DL. Hit identification of IKKβ natural product inhibitor. Bmc Pharmacology & Toxicology. 14: 3. PMID 23294515 DOI: 10.1186/2050-6511-14-3  0.428
2013 Ma DL, Chan DS, Leung CH. Drug repositioning by structure-based virtual screening. Chemical Society Reviews. 42: 2130-41. PMID 23288298 DOI: 10.1039/C2Cs35357A  0.467
2013 Leung KH, He HZ, Ma VP, Chan DS, Leung CH, Ma DL. A luminescent G-quadruplex switch-on probe for the highly selective and tunable detection of cysteine and glutathione. Chemical Communications (Cambridge, England). 49: 771-3. PMID 23192322 DOI: 10.1039/C2Cc37710A  0.504
2013 Yang H, Zhong HJ, Leung KH, Chan DS, Ma VP, Fu WC, Nanjunda R, Wilson WD, Ma DL, Leung CH. Structure-based design of flavone derivatives as c-myc oncogene down-regulators. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 48: 130-41. PMID 23127826 DOI: 10.1016/J.Ejps.2012.10.010  0.5
2013 He HZ, Leung KH, Yang H, Chan DS, Leung CH, Zhou J, Bourdoncle A, Mergny JL, Ma DL. Label-free detection of sub-nanomolar lead(II) ions in aqueous solution using a metal-based luminescent switch-on probe. Biosensors & Bioelectronics. 41: 871-4. PMID 23040875 DOI: 10.1016/J.Bios.2012.08.060  0.528
2013 Leung CH, Chan DS, Ma VP, Ma DL. DNA-binding small molecules as inhibitors of transcription factors. Medicinal Research Reviews. 33: 823-46. PMID 22549740 DOI: 10.1002/Med.21266  0.472
2012 Zhong HJ, Yang H, Chan DS, Leung CH, Wang HM, Ma DL. A metal-based inhibitor of NEDD8-activating enzyme. Plos One. 7: e49574. PMID 23185368 DOI: 10.1371/Journal.Pone.0049574  0.517
2012 Ma DL, Chan DS, Fu WC, He HZ, Yang H, Yan SC, Leung CH. Discovery of a natural product-like c-myc G-quadruplex DNA groove-binder by molecular docking. Plos One. 7: e43278. PMID 22912844 DOI: 10.1371/Journal.Pone.0043278  0.49
2012 Leung CH, Zhong HJ, Yang H, Cheng Z, Chan DS, Ma VP, Abagyan R, Wong CY, Ma DL. A metal-based inhibitor of tumor necrosis factor-α. Angewandte Chemie (International Ed. in English). 51: 9010-4. PMID 22807261 DOI: 10.1002/Anie.201202937  0.458
2012 Zhong HJ, Ma VP, Cheng Z, Chan DS, He HZ, Leung KH, Ma DL, Leung CH. Discovery of a natural product inhibitor targeting protein neddylation by structure-based virtual screening. Biochimie. 94: 2457-60. PMID 22709868 DOI: 10.1016/J.Biochi.2012.06.004  0.537
2012 Ma DL, He HZ, Ma VP, Chan DS, Leung KH, Zhong HJ, Lu L, Mergny JL, Leung CH. Label-free sensing of pH and silver nanoparticles using an "OR" logic gate. Analytica Chimica Acta. 733: 78-83. PMID 22704379 DOI: 10.1016/J.Aca.2012.04.041  0.467
2012 He HZ, Chan DS, Leung CH, Ma DL. A highly selective G-quadruplex-based luminescent switch-on probe for the detection of gene deletion. Chemical Communications (Cambridge, England). 48: 9462-4. PMID 22692458 DOI: 10.1039/C2Cc32253F  0.526
2012 Ma DL, Chan DS, Ma VP, Leung KH, Zhong HJ, Leung CH. Current advancements in Aβ luminescent probes and inhibitors of Aβ aggregation. Current Alzheimer Research. 9: 830-43. PMID 22631884 DOI: 10.2174/156720512802455377  0.4
2012 Ma DL, Ma VP, Chan DS, Leung KH, Zhong HJ, Leung CH. In silico screening of quadruplex-binding ligands. Methods (San Diego, Calif.). 57: 106-14. PMID 22391485 DOI: 10.1016/J.Ymeth.2012.02.001  0.519
2012 He HZ, Ma VP, Leung KH, Chan DS, Yang H, Cheng Z, Leung CH, Ma DL. A label-free G-quadruplex-based switch-on fluorescence assay for the selective detection of ATP. The Analyst. 137: 1538-40. PMID 22343772 DOI: 10.1039/C2An15999F  0.503
2012 Leung CH, Chan DS, He HZ, Cheng Z, Yang H, Ma DL. Luminescent detection of DNA-binding proteins. Nucleic Acids Research. 40: 941-55. PMID 21967849 DOI: 10.1093/Nar/Gkr763  0.509
2011 Ma DL, Kwan MH, Chan DS, Lee P, Yang H, Ma VP, Bai LP, Jiang ZH, Leung CH. Crystal violet as a fluorescent switch-on probe for i-motif: label-free DNA-based logic gate. The Analyst. 136: 2692-6. PMID 21566850 DOI: 10.1039/C1An15091J  0.477
2011 Ma DL, Chan DS, Lee P, Kwan MH, Leung CH. Molecular modeling of drug-DNA interactions: virtual screening to structure-based design. Biochimie. 93: 1252-66. PMID 21514356 DOI: 10.1016/J.Biochi.2011.04.002  0.526
2011 Chan DS, Yang H, Kwan MH, Cheng Z, Lee P, Bai LP, Jiang ZH, Wong CY, Fong WF, Leung CH, Ma DL. Structure-based optimization of FDA-approved drug methylene blue as a c-myc G-quadruplex DNA stabilizer. Biochimie. 93: 1055-64. PMID 21377506 DOI: 10.1016/J.Biochi.2011.02.013  0.533
2011 Leung CH, Chan DS, Kwan MH, Cheng Z, Wong CY, Zhu GY, Fong WF, Ma DL. Structure-based repurposing of FDA-approved drugs as TNF-α inhibitors. Chemmedchem. 6: 765-8. PMID 21365767 DOI: 10.1002/Cmdc.201100016  0.452
2011 Ma DL, Chan DS, Man BY, Leung CH. Oligonucleotide-based luminescent detection of metal ions. Chemistry, An Asian Journal. 6: 986-1003. PMID 21337527 DOI: 10.1002/Asia.201000870  0.451
2011 Leung CH, Chan DS, Yang H, Abagyan R, Lee SM, Zhu GY, Fong WF, Ma DL. A natural product-like inhibitor of NEDD8-activating enzyme. Chemical Communications (Cambridge, England). 47: 2511-3. PMID 21240405 DOI: 10.1039/C0Cc04927A  0.493
2011 Leung CH, Chan DS, Man BY, Wang CJ, Lam W, Cheng YC, Fong WF, Hsiao WL, Ma DL. Simple and convenient G-quadruplex-based turn-on fluorescence assay for 3' → 5' exonuclease activity. Analytical Chemistry. 83: 463-6. PMID 21114271 DOI: 10.1021/Ac1025896  0.528
2010 Man BY, Chan DS, Yang H, Ang SW, Yang F, Yan SC, Ho CM, Wu P, Che CM, Leung CH, Ma DL. A selective G-quadruplex-based luminescent switch-on probe for the detection of nanomolar silver(I) ions in aqueous solution. Chemical Communications (Cambridge, England). 46: 8534-6. PMID 20668746 DOI: 10.1039/C0Cc01201G  0.51
2010 Lee HM, Chan DS, Yang F, Lam HY, Yan SC, Che CM, Ma DL, Leung CH. Identification of natural product fonsecin B as a stabilizing ligand of c-myc G-quadruplex DNA by high-throughput virtual screening. Chemical Communications (Cambridge, England). 46: 4680-2. PMID 20383387 DOI: 10.1039/B926359D  0.506
2010 Chan DS, Lee HM, Yang F, Che CM, Wong CC, Abagyan R, Leung CH, Ma DL. Structure-based discovery of natural-product-like TNF-α inhibitors. Angewandte Chemie (International Ed. in English). 49: 2860-4. PMID 20235259 DOI: 10.1002/Anie.200907360  0.448
2009 Chan DS, Lee HM, Che CM, Leung CH, Ma DL. A selective oligonucleotide-based luminescent switch-on probe for the detection of nanomolar mercury(II) ion in aqueous solution. Chemical Communications (Cambridge, England). 7479-81. PMID 20024252 DOI: 10.1039/B913995H  0.495
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