Year |
Citation |
Score |
2023 |
Rosado-Sánchez I, Haque M, Salim K, Speck M, Fung VC, Boardman DA, Mojibian M, Raimondi G, Levings MK. Tregs integrate native and CAR-mediated costimulatory signals for control of allograft rejection. Jci Insight. 8. PMID 37669115 DOI: 10.1172/jci.insight.167215 |
0.346 |
|
2023 |
Spanier JA, Fung V, Wardell CM, Alkhatib MH, Chen Y, Swanson LA, Dwyer AJ, Weno ME, Silva N, Mitchell JS, Orban PC, Mojibian M, Verchere CB, Fife BT, Levings MK. Insulin B peptide-MHC class II-specific chimeric antigen receptor-Tregs prevent autoimmune diabetes in mice. The Journal of Clinical Investigation. PMID 37561596 DOI: 10.1172/JCI168601 |
0.326 |
|
2023 |
Ellis CE, Mojibian M, Ida S, Fung VCW, Skovsø S, McIver E, O'Dwyer S, Webber TD, Braam MJS, Saber N, Sasaki S, Lynn FC, Kieffer TJ, Levings MK. Human A2-CAR T Cells Reject HLA-A2+ Human Islets Transplanted Into Mice Without Inducing Graft-Versus-Host Disease. Transplantation. PMID 37528526 DOI: 10.1097/TP.0000000000004709 |
0.381 |
|
2023 |
Tuomela K, Salim K, Levings MK. Eras of designer Tregs: Harnessing synthetic biology for immune suppression. Immunological Reviews. PMID 37522861 DOI: 10.1111/imr.13254 |
0.443 |
|
2023 |
Kim JV, Assadian S, Hollander Z, Burns P, Shannon CP, Lam K, Toma M, Ignaszewski A, Davies RA, Delgado D, Haddad H, Isaac D, Kim D, Mui A, Rajda M, ... ... Levings MK, et al. Regulatory T Cell Biomarkers Identify Patients at Risk of Developing Acute Cellular Rejection in the First Year Following Heart Transplantation. Transplantation. PMID 37365692 DOI: 10.1097/TP.0000000000004607 |
0.375 |
|
2023 |
Tuomela K, Levings MK. Acidity promotes the differentiation of immunosuppressive regulatory T cells. European Journal of Immunology. e2350511. PMID 37097063 DOI: 10.1002/eji.202350511 |
0.391 |
|
2023 |
Stankiewicz LN, Salim K, Flaschner EA, Wang YX, Edgar JM, Lin BZ, Bingham GC, Major MC, Jones RD, Blau HM, Rideout EJ, Levings MK, Zandstra PW, Rossi FM. Sex biased human thymic architecture guides T cell development through spatially defined niches. Biorxiv : the Preprint Server For Biology. PMID 37090676 DOI: 10.1101/2023.04.13.536804 |
0.37 |
|
2023 |
Haque M, Boardman DA, Levings MK. Alleviating graft-versus-host disease by directing regulatory T cells to the gut … it is all about location, location, location. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 37059178 DOI: 10.1016/j.ajt.2023.04.010 |
0.328 |
|
2023 |
Lamarche C, Ward-Hartstonge K, Mi T, Lin DTS, Huang Q, Brown A, Edwards K, Novakovsky GE, Qi CN, Kobor MS, Zebley CC, Weber EW, Mackall CL, Levings MK. Tonic-signaling chimeric antigen receptors drive human regulatory T cell exhaustion. Proceedings of the National Academy of Sciences of the United States of America. 120: e2219086120. PMID 36972454 DOI: 10.1073/pnas.2219086120 |
0.509 |
|
2023 |
Colpitts SJ, Budd MA, Monajemi M, Reid KT, Murphy JM, Ivison S, Verchere CB, Levings MK, Crome SQ. Strategies for optimizing CITE-seq for human islets and other tissues. Frontiers in Immunology. 14: 1107582. PMID 36936943 DOI: 10.3389/fimmu.2023.1107582 |
0.379 |
|
2023 |
Halvorson T, Tuomela K, Levings MK. Targeting regulatory T cell metabolism in disease: novel therapeutic opportunities. European Journal of Immunology. e2250002. PMID 36891988 DOI: 10.1002/eji.202250002 |
0.317 |
|
2023 |
Spanier JA, Fung V, Wardell CM, Alkhatib MH, Chen Y, Swanson LA, Dwyer AJ, Weno ME, Silva N, Mitchell JS, Orban PC, Mojibian M, Verchere CB, Fife BT, Levings MK. Insulin B peptide-MHC class II-specific chimeric antigen receptor-Tregs prevent autoimmune diabetes. Biorxiv : the Preprint Server For Biology. PMID 36865264 DOI: 10.1101/2023.02.23.529737 |
0.331 |
|
2023 |
Ellis CE, Mojibian M, Ida S, Fung VCW, Skovsø S, McIver E, O'Dwyer S, Webber TD, Braam MJS, Saber N, Kieffer TJ, Levings MK. Human A2-CAR T cells reject HLA-A2+ human islets transplanted into mice without inducing graft versus host disease. Biorxiv : the Preprint Server For Biology. PMID 36865123 DOI: 10.1101/2023.02.23.529741 |
0.381 |
|
2023 |
Poloni C, Schonhofer C, Ivison S, Levings MK, Steiner TS, Cook L. T cell activation induced marker assays in health and disease. Immunology and Cell Biology. PMID 36825901 DOI: 10.1111/imcb.12636 |
0.387 |
|
2022 |
Haque M, Boardman DA, Lam AJ, MacDonald KN, Sanderink L, Huang Q, Fung VCW, Ivison S, Mojibian M, Levings MK. Modelling Graft-Versus-Host Disease in Mice Using Human Peripheral Blood Mononuclear Cells. Bio-Protocol. 12. PMID 36561116 DOI: 10.21769/BioProtoc.4566 |
0.801 |
|
2022 |
Boardman DA, Wong MQ, Rees WD, Wu D, Himmel ME, Orban PC, Vent-Schmidt J, Zachos NC, Steiner TS, Levings MK. Flagellin-specific human CAR Tregs for immune regulation in IBD. Journal of Autoimmunity. 134: 102961. PMID 36470208 DOI: 10.1016/j.jaut.2022.102961 |
0.404 |
|
2022 |
MacDonald KN, Salim K, Levings MK. Manufacturing next-generation regulatory T-cell therapies. Current Opinion in Biotechnology. 78: 102822. PMID 36332342 DOI: 10.1016/j.copbio.2022.102822 |
0.416 |
|
2022 |
Lordén G, Lam AJ, Levings MK, Newton AC. PHLPP Signaling in Immune Cells. Current Topics in Microbiology and Immunology. 436: 117-143. PMID 36243842 DOI: 10.1007/978-3-031-06566-8_5 |
0.786 |
|
2022 |
Lauener M, AzadPour S, Abdossamadi S, Parthasarathy V, Ng B, Ostroumov E, Cuvelier GDE, Levings MK, MacDonald KN, Kariminia A, Schultz KR. CD56brightCD16- natural killer cells as an important regulatory mechanism in chronic graftversus-host disease. Haematologica. PMID 36200416 DOI: 10.3324/haematol.2022.280653 |
0.403 |
|
2022 |
MacDonald KN, Hall MG, Ivison S, Gandhi S, Klein Geltink RI, Piret JM, Levings MK. Consequences of adjusting cell density and feed frequency on serum-free expansion of thymic regulatory T cells. Cytotherapy. PMID 36008207 DOI: 10.1016/j.jcyt.2022.06.006 |
0.404 |
|
2022 |
Proics E, David M, Mojibian M, Speck M, Lounnas-Mourey N, Govehovitch A, Baghdadi W, Desnouveaux J, Bastian H, Freschi L, Privat G, Pouzet C, Grossi M, Heimendinger P, Abel T, ... ... Levings MK, et al. Preclinical assessment of antigen-specific chimeric antigen receptor regulatory T cells for use in solid organ transplantation. Gene Therapy. PMID 35931871 DOI: 10.1038/s41434-022-00358-x |
0.359 |
|
2022 |
Lam AJ, Haque M, Ward-Hartstonge KA, Uday P, Wardell CM, Gillies JK, Speck M, Mojibian M, Klein Geltink RI, Levings MK. PTEN is required for human Treg suppression of costimulation in vitro. European Journal of Immunology. PMID 35746855 DOI: 10.1002/eji.202249888 |
0.82 |
|
2022 |
Yang JHM, Ward-Hartstonge KA, Perry DJ, Blanchfield JL, Posgai AL, Wiedeman AE, Diggins K, Rahman A, Tree TIM, Brusko TM, Levings MK, James EA, Kent SC, Speake C, Homann D, et al. Guidelines for standardizing T-cell cytometry assays to link biomarkers, mechanisms, and disease outcomes in type 1 diabetes. European Journal of Immunology. 52: 372-388. PMID 35025103 DOI: 10.1002/eji.202049067 |
0.33 |
|
2022 |
Boardman DA, Levings MK. Emerging strategies for treating autoimmune disorders with genetically modified Treg cells. The Journal of Allergy and Clinical Immunology. 149: 1-11. PMID 34998473 DOI: 10.1016/j.jaci.2021.11.007 |
0.417 |
|
2021 |
Huang Q, Lam AJ, Boardman DA, Dawson NAJ, Levings MK. Suppression of Human Dendritic Cells by Regulatory T Cells. Bio-Protocol. 11: e4217. PMID 34859131 DOI: 10.21769/BioProtoc.4217 |
0.835 |
|
2021 |
Lam AJ, Uday P, Gillies JK, Levings MK. Helios is a marker, not a driver, of human Treg stability. European Journal of Immunology. PMID 34561855 DOI: 10.1002/eji.202149318 |
0.828 |
|
2021 |
Budd MA, Monajemi M, Colpitts SJ, Crome SQ, Verchere CB, Levings MK. Interactions between islets and regulatory immune cells in health and type 1 diabetes. Diabetologia. 64: 2378-2388. PMID 34550422 DOI: 10.1007/s00125-021-05565-6 |
0.352 |
|
2021 |
Lam AJ, Lin DTS, Gillies JK, Uday P, Pesenacker AM, Kobor MS, Levings MK. Optimized CRISPR-mediated gene knockin reveals FOXP3-independent maintenance of human Treg identity. Cell Reports. 36: 109494. PMID 34348163 DOI: 10.1016/j.celrep.2021.109494 |
0.805 |
|
2021 |
Pj White M, Smyth DJ, Cook L, Ziegler SF, Levings MK, Maizels RM. The parasite cytokine mimic Hp-TGM potently replicates the regulatory effects of TGF-β on murine CD4 T cells. Immunology and Cell Biology. PMID 33988885 DOI: 10.1111/imcb.12479 |
0.352 |
|
2021 |
Cook L, Reid KT, Häkkinen E, de Bie B, Tanaka S, Smyth DJ, White MP, Wong MQ, Huang Q, Gillies JK, Zeigler SF, Maizels RM, Levings MK. Induction of stable human FOXP3 Tregs by a parasite-derived TGF-β mimic. Immunology and Cell Biology. PMID 33929751 DOI: 10.1111/imcb.12475 |
0.429 |
|
2021 |
Fung VCW, Rosado-Sánchez I, Levings MK. Transduction of Human T Cell Subsets with Lentivirus. Methods in Molecular Biology (Clifton, N.J.). 2285: 227-254. PMID 33928557 DOI: 10.1007/978-1-0716-1311-5_19 |
0.443 |
|
2021 |
Ahmad I, Bijl J, Ivison S, Atenafu EG, Panzarella T, Broady R, Szwajcer D, Walker I, Kim DD, Bredeson C, Foley R, Hogge DE, Allan D, Delisle J, Schultz K, ... ... Levings M, et al. Continuous Alloreactive T Cell Depletion and Regulatory T Cell Expansion for the Treatment of Steroid- Refractory or Dependent Chronic GVHD – a Multicentre Phase II Clinical Trial (CARE Trial) Transplantation and Cellular Therapy. 27: S285. DOI: 10.1016/S2666-6367(21)00364-X |
0.308 |
|
2020 |
Scott DW, Levings MK. Novel T regulatory cells come of age: The curious incident of a mouse in Tennessee, delayed thymectomy and chimeric receptors! Cellular Immunology. 359: 104253. PMID 33307362 DOI: 10.1016/j.cellimm.2020.104253 |
0.315 |
|
2020 |
Wardell CM, MacDonald KN, Levings MK, Cook L. Cross talk between human regulatory T cells and antigen presenting cells: Lessons for clinical applications. European Journal of Immunology. PMID 33301176 DOI: 10.1002/eji.202048746 |
0.502 |
|
2020 |
Wu D, Wong MQ, Vent-Schmidt J, Boardman DA, Steiner TS, Levings MK. A method for expansion and retroviral transduction of mouse regulatory T cells. Journal of Immunological Methods. 112931. PMID 33221458 DOI: 10.1016/j.jim.2020.112931 |
0.469 |
|
2020 |
Rosado-Sánchez I, Levings MK. Building a CAR-Treg: Going from the basic to the luxury model. Cellular Immunology. 358: 104220. PMID 33096321 DOI: 10.1016/j.cellimm.2020.104220 |
0.47 |
|
2020 |
Dawson NAJ, Rosado-Sánchez I, Novakovsky GE, Fung VCW, Huang Q, McIver E, Sun G, Gillies J, Speck M, Orban PC, Mojibian M, Levings MK. Functional effects of chimeric antigen receptor co-receptor signaling domains in human regulatory T cells. Science Translational Medicine. 12. PMID 32817364 DOI: 10.1126/Scitranslmed.Aaz3866 |
0.514 |
|
2020 |
Cook L, Levings MK. T-Cell Specificity Matters in IBD: Impaired IL10 Production Revealed by OmpC-Tetramers. Cellular and Molecular Gastroenterology and Hepatology. PMID 32645294 DOI: 10.1016/J.Jcmgh.2020.06.007 |
0.452 |
|
2020 |
Wu D, Wong CK, Han JM, Orban PC, Huang Q, Gillies J, Mojibian M, Gibson WT, Levings MK. T reg-specific insulin receptor deletion prevents diet-induced and age-associated metabolic syndrome. The Journal of Experimental Medicine. 217. PMID 32478834 DOI: 10.1084/Jem.20191542 |
0.405 |
|
2020 |
Boardman DA, Garcia RV, Ivison SM, Bressler B, Dhar TM, Zhao Q, Levings MK. Pharmacological inhibition of RORC2 enhances human Th17-Treg stability and function. European Journal of Immunology. PMID 32388860 DOI: 10.1002/Eji.201948435 |
0.499 |
|
2020 |
Sicard A, Lamarche C, Speck M, Wong M, Rosado-Sánchez I, Blois M, Glaichenhaus N, Mojibian M, Levings MK. Donor-specific chimeric antigen receptor Tregs limit rejection in naive but not sensitized allograft recipients. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 31957209 DOI: 10.1111/Ajt.15787 |
0.407 |
|
2020 |
Dijke E, Ellis T, Larsen I, Rebeyka I, Freed D, Al-Aklabi M, Levings M, West L. Human Leukocyte Antigen (HLA) Class II Expression on Regulatory T Cells (Tregs) Isolated from Discarded Human Thymus is Induced by In Vitro Expansion Conditions The Journal of Heart and Lung Transplantation. 39: S178-S179. DOI: 10.1016/J.Healun.2020.01.755 |
0.431 |
|
2019 |
MacDonald KN, Ivison S, Hippen KL, Hoeppli RE, Hall M, Zheng G, Dijke IE, Aklabi MA, Freed DH, Rebeyka I, Gandhi S, West LJ, Piret JM, Blazar BR, Levings MK. Cryopreservation timing is a critical process parameter in a thymic regulatory T-cell therapy manufacturing protocol. Cytotherapy. PMID 31810768 DOI: 10.1016/J.Jcyt.2019.10.011 |
0.494 |
|
2019 |
Cook L, Lisko DJ, Wong MQ, Garcia RV, Himmel ME, Seidman EG, Bressler B, Levings MK, Steiner TS. Analysis of flagellin-specific adaptive immunity reveals links to dysbiosis in patients with Inflammatory Bowel Disease. Cellular and Molecular Gastroenterology and Hepatology. PMID 31790809 DOI: 10.1016/J.Jcmgh.2019.11.012 |
0.459 |
|
2019 |
Wu D, Huang Q, Orban PC, Levings MK. Ectopic germline recombination activity of the widely-used Foxp3-YFP-Cre mouse: a case-report. Immunology. PMID 31713233 DOI: 10.1111/Imm.13153 |
0.341 |
|
2019 |
Cossarizza A, Chang HD, Radbruch A, Acs A, Adam D, Adam-Klages S, Agace WW, Aghaeepour N, Akdis M, Allez M, Almeida LN, Alvisi G, Anderson G, Andrä I, Annunziato F, ... ... Levings MK, et al. Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition). European Journal of Immunology. 49: 1457-1973. PMID 31633216 DOI: 10.1002/Eji.201970107 |
0.32 |
|
2019 |
Cook L, Stahl M, Han X, Nazli A, MacDonald KN, Wong MQ, Tsai K, Dizzell S, Jacobson K, Bressler B, Kaushic C, Vallance BA, Steiner TS, Levings MK. Suppressive and Gut Reparative Functions of Human Type 1 T-regulatory Cells. Gastroenterology. PMID 31513797 DOI: 10.1053/J.Gastro.2019.09.002 |
0.571 |
|
2019 |
Wu D, Levings MK. A New Mechanism of Action in Human and Mouse Treg Cells: The Ke(y)to Suppression. Immunity. 50: 1122-1124. PMID 31117006 DOI: 10.1016/J.Immuni.2019.04.008 |
0.508 |
|
2019 |
MacDonald KN, Piret JM, Levings MK. Methods to manufacture regulatory T cells for cell therapy. Clinical and Experimental Immunology. PMID 30913302 DOI: 10.1111/Cei.13297 |
0.458 |
|
2019 |
Lam AJ, MacDonald KN, Pesenacker AM, Juvet SC, Morishita KA, Bressler B, Pan JG, Sidhu SS, Rioux JD, Levings MK. Innate Control of Tissue-Reparative Human Regulatory T Cells. Journal of Immunology (Baltimore, Md. : 1950). PMID 30850479 DOI: 10.4049/Jimmunol.1801330 |
0.815 |
|
2019 |
Lad D, Huang Q, Hoeppli R, Garcia R, Xu L, Levings M, Song K, Broady R. Evaluating the role of Tregs in the progression of multiple myeloma. Leukemia & Lymphoma. 1-9. PMID 30773086 DOI: 10.1080/10428194.2019.1579324 |
0.532 |
|
2019 |
Dawson NA, Lamarche C, Hoeppli RE, Bergqvist P, Fung V, McIver E, Huang Q, Gillies J, Speck M, Orban PC, Bush JW, Mojibian M, Levings MK. Systematic testing and specificity mapping of alloantigen-specific chimeric antigen receptors in T regulatory cells. Jci Insight. PMID 30753169 DOI: 10.1172/Jci.Insight.123672 |
0.429 |
|
2019 |
Pesenacker AM, Chen V, Gillies J, Speake C, Marwaha AK, Sun AC, Chow S, Tan R, Elliott T, Dutz JP, Tebbutt SJ, Levings MK. Treg gene signatures predict and measure type 1 diabetes trajectory. Jci Insight. PMID 30730852 DOI: 10.1172/Jci.Insight.123879 |
0.312 |
|
2019 |
Dijke E, Ellis T, Larsen I, Rebeyka I, Freed D, Al Aklabi M, Levings M, West L. OR12 Expansion conditions affect human leukocyte antigens (HLA) Class II expression on thymic regulatory T cells (TREGS) Human Immunology. 80: 16. DOI: 10.1016/J.Humimm.2019.07.014 |
0.454 |
|
2018 |
Wu D, Han JM, Yu X, Lam AJ, Hoeppli RE, Pesenacker AM, Huang Q, Chen V, Speake C, Yorke E, Nguyen N, Sampath S, Harris D, Levings MK. Characterization of regulatory T cells in obese omental adipose tissue in humans. European Journal of Immunology. PMID 30566246 DOI: 10.1002/Eji.201847570 |
0.79 |
|
2018 |
Ivison S, Malek M, Garcia RV, Broady R, Halpin A, Richaud M, Brant RF, Wang SI, Goupil M, Guan Q, Ashton P, Warren J, Rajab A, Urschel S, Kumar D, ... ... Levings MK, et al. A standardized immune phenotyping and automated data analysis platform for multicenter biomarker studies. Jci Insight. 3. PMID 30518691 DOI: 10.1172/Jci.Insight.121867 |
0.322 |
|
2018 |
Sicard A, Boardman DA, Levings MK. Taking regulatory T-cell therapy one step further. Current Opinion in Organ Transplantation. 23: 509-515. PMID 30063480 DOI: 10.1097/Mot.0000000000000566 |
0.503 |
|
2018 |
Hoeppli RE, MacDonald KN, Leclair P, Fung VCW, Mojibian M, Gillies J, Rahavi SMR, Campbell AIM, Gandhi SK, Pesenacker AM, Reid G, Lim CJ, Levings MK. Tailoring the homing capacity of human Tregs for directed migration to sites of Th1-inflammation or intestinal regions. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 29766641 DOI: 10.1111/Ajt.14936 |
0.53 |
|
2018 |
Sicard A, Levings MK, Scott DW. Engineering Therapeutic T Cells to Suppress Alloimmune Responses Using TCRs, CARs or BARs. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 29603617 DOI: 10.1111/Ajt.14747 |
0.521 |
|
2018 |
Lamarche C, Levings MK. Guiding regulatory T cells to the allograft. Current Opinion in Organ Transplantation. 23: 106-113. PMID 29140829 DOI: 10.1097/Mot.0000000000000483 |
0.492 |
|
2018 |
Lam AJ, Huang H, Pan JG, Sidhu SS, Charron G, Ivison SM, Rioux JD, Levings MK. Human Regulatory T Cell Potential for Tissue Repair Via IL-33/ST2 and Amphiregulin Transplantation. 102. DOI: 10.1097/01.Tp.0000543061.12872.C0 |
0.803 |
|
2018 |
Alonso-Guallart P, Duran-Struuck R, Stern J, Berglund E, Llore N, Zitsman J, Pierre G, Kofman S, Danton M, Gokova S, Lopes E, McMurchy A, Tang Q, Levings M, Sykes M, et al. Megadose Bone Marrow and Regulatory T cells for the Induction of Immune Tolerance in Non-Human Primates Through Durable Mixed Hematopoietic Chimerism Across MHC-barriers Transplantation. 102: S263-S264. DOI: 10.1097/01.Tp.0000542954.80179.6B |
0.473 |
|
2018 |
Dawson NAJ, Lamarche C, Bergqvist P, Huang Q, Mojibian M, Gillies J, Orban PC, Hoeppli R, Levings MK. Humanization and Pre-Clinical Validation of an Anti-HLA-A*02: 01 Chimeric Antigen Receptor for use with Regulatory T cells to Enhance Transplant Tolerance. Transplantation. 102. DOI: 10.1097/01.Tp.0000542905.98105.1F |
0.464 |
|
2018 |
Bernaldo-de-Quiros E, Camino M, Gil-Jaurena JM, Fernández-Santos E, Gil N, Panadero E, Medrano C, López R, Martínez-Bonet M, Hernández-Flórez D, Levings MK, West LJ, Pion M, Correa-Rocha R. “First-In-Human” Clinical Trial Employing Adoptive Transfer of Autologous Thymus-Derived Treg Cells (thyTreg) to Prevent Graft Rejection in Heart-Transplanted Children Transplantation. 102. DOI: 10.1097/01.Tp.0000542859.38902.Af |
0.325 |
|
2017 |
Fuchs A, Gliwiński M, Grageda N, Spiering R, Abbas AK, Appel S, Bacchetta R, Battaglia M, Berglund D, Blazar B, Bluestone JA, Bornhäuser M, Ten Brinke A, Brusko TM, Cools N, ... ... Levings M, et al. Minimum Information about T Regulatory Cells: A Step toward Reproducibility and Standardization. Frontiers in Immunology. 8: 1844. PMID 29379498 DOI: 10.3389/Fimmu.2017.01844 |
0.499 |
|
2017 |
Dawson NAJ, Vent-Schmidt J, Levings MK. Engineered Tolerance: Tailoring Development, Function, and Antigen-Specificity of Regulatory T Cells. Frontiers in Immunology. 8: 1460. PMID 29163527 DOI: 10.3389/Fimmu.2017.01460 |
0.56 |
|
2017 |
Ivison S, des Rosiers C, Lesage S, Rioux JD, Levings MK. Biomarker-guided stratification of autoimmune patients for biologic therapy. Current Opinion in Immunology. 49: 56-63. PMID 29053992 DOI: 10.1016/J.Coi.2017.09.006 |
0.321 |
|
2017 |
Cossarizza A, Chang HD, Radbruch A, Andrä I, Annunziato F, Bacher P, Barnaba V, Battistini L, Bauer WM, Baumgart S, Becher B, Beisker W, Berek C, Blanco A, Borsellino G, ... ... Levings MK, et al. Guidelines for the use of flow cytometry and cell sorting in immunological studies. European Journal of Immunology. 47: 1584-1797. PMID 29023707 DOI: 10.1002/Eji.201646632 |
0.409 |
|
2017 |
Kariminia A, Ivison S, Ng B, Rozmus J, Sung S, Varshney A, Aljurf M, Lachance S, Walker I, Toze C, Lipton J, Lee SJ, Szer J, Doocey R, Lewis I, ... ... Levings MK, et al. CD56bright NK regulatory cells in filgrastim primed donor blood or marrow products regulate chronic GvHD: CBMTG randomized 0601 study results. Haematologica. PMID 28935847 DOI: 10.3324/Haematol.2017.170928 |
0.436 |
|
2017 |
Becker M, Levings MK, Daniel C. Adipose-tissue regulatory T cells: Critical players in adipose-immune crosstalk. European Journal of Immunology. PMID 28849586 DOI: 10.1002/Eji.201646739 |
0.506 |
|
2017 |
Dawson NAJ, Levings MK. Antigen-specific regulatory T cells: are police CARs the answer? Translational Research : the Journal of Laboratory and Clinical Medicine. PMID 28688236 DOI: 10.1016/J.Trsl.2017.06.009 |
0.533 |
|
2017 |
Golec DP, Hoeppli RE, Henao Caviedes LM, McCann J, Levings MK, Baldwin TA. Thymic progenitors of TCRαβ(+) CD8αα intestinal intraepithelial lymphocytes require RasGRP1 for development. The Journal of Experimental Medicine. PMID 28652304 DOI: 10.1084/Jem.20170844 |
0.41 |
|
2017 |
Lad D, Hoeppli R, Huang Q, Garcia R, Xu L, Toze C, Broady R, Levings M. Regulatory T-cells drive immune dysfunction in CLL. Leukemia & Lymphoma. 1-4. PMID 28573905 DOI: 10.1080/10428194.2017.1330475 |
0.527 |
|
2017 |
Lam AJ, Hoeppli RE, Levings MK. Harnessing Advances in T Regulatory Cell Biology for Cellular Therapy in Transplantation. Transplantation. PMID 28376037 DOI: 10.1097/Tp.0000000000001757 |
0.811 |
|
2017 |
Cook L, Munier CM, Seddiki N, van Bockel D, Ontiveros N, Hardy MY, Gillies JK, Levings MK, Reid H, Peterson J, Rossjohn J, Anderson RP, Zaunders J, Tye-Din JA, Kelleher AD. Circulating Gluten-Specific FOXP3(+)CD39(+) Regulatory T Cells Have Impaired Suppressive Function in Celiac Disease. The Journal of Allergy and Clinical Immunology. PMID 28283419 DOI: 10.1016/J.Jaci.2017.02.015 |
0.543 |
|
2017 |
Hoeppli RE, Dijke E, Campbell A, West LJ, Levings MK. Migration Capacity of Thymic Regulatory T Cells can be Tuned by Expansion in Cytokine-Enriched Culture Conditions Transplantation. 101. DOI: 10.1097/01.Tp.0000520352.47820.13 |
0.472 |
|
2017 |
Quirós EBd, Pérez VA, Clemente M, Gil-Jaurena JM, González MT, Pion M, Lombardi G, West LJ, Levings M, Correa-Rocha R. Thymus-Derived Treg Infusion to Prevent Graft Rejection in Heart-Transplanted Children: Initial Exploration of a New Therapeutic Arsenal to Boost Immune Tolerance Transplantation. 101. DOI: 10.1097/01.Tp.0000520350.40197.6B |
0.33 |
|
2017 |
MacDonald K, Hoeppli R, Piret J, Dijke E, West L, Levings M. Development of GMP-Compatible Protocols for Thymus-Derived Regulatory T Cell Expansion Transplantation. 101: S9. DOI: 10.1097/01.Tp.0000520303.10595.5E |
0.495 |
|
2017 |
Cook L, Wong M, Rees W, Lau T, Levings M, Steiner T. CD4+ T Cells Specific for C. difficile Toxins are a Marker of Patients with Active Relapsing Disease Open Forum Infectious Diseases. 4. DOI: 10.1093/Ofid/Ofx163.948 |
0.436 |
|
2017 |
Cook L, Wong MQ, Garcia R, Himmel ME, Bressler B, Seidman EG, Steiner TS, Levings MK. A Novel Whole Blood Assay Detects Flagellin-Specific CD4 + T Cells in Patients with Inflammatory Bowel Disease Gastroenterology. 152: S615. DOI: 10.1016/S0016-5085(17)32185-6 |
0.439 |
|
2017 |
Dijke E, Hoeppli R, Larsen I, Rebeyka I, Ross D, Levings M, West L. OR42 Expanded thymic regulatory T cells (Tregs) have low class I HLA expression levels and are HLA-DR negative – Potential for ‘Off-The-Shelf’ Cellular Therapy? Human Immunology. 78: 40. DOI: 10.1016/J.Humimm.2017.06.048 |
0.488 |
|
2017 |
Lad D, Broady R, Huang J, Hoeppli R, Pesenacker A, Garcia R, Xu L, Levings M, Song K. Evaluating the Role of Tregs in the Progression of Multiple Myeloma Clinical Lymphoma, Myeloma & Leukemia. 17. DOI: 10.1016/J.Clml.2017.03.075 |
0.312 |
|
2016 |
Duran-Struuck R, Sondermeijer HP, Bühler L, Alonso-Guallart P, Zitsman J, Kato Y, Wu A, McMurchy AN, Woodland D, Griesemer A, Martinez M, Boskovic S, Kawai T, Cosimi AB, Wuu CS, ... ... Levings M, et al. Effect of ex vivo Expanded Recipient Regulatory T Cells on Hematopoietic Chimerism and Kidney Allograft Tolerance Across MHC Barriers in Cynomolgus Macaques. Transplantation. PMID 27846155 DOI: 10.1097/Tp.0000000000001559 |
0.509 |
|
2016 |
Pesenacker AM, Cook L, Levings MK. The role of FOXP3 in autoimmunity. Current Opinion in Immunology. 43: 16-23. PMID 27544816 DOI: 10.1016/J.Coi.2016.07.004 |
0.498 |
|
2016 |
Hoeppli RE, MacDonald KG, Levings MK, Cook L. How antigen specificity directs regulatory T-cell function: self, foreign and engineered specificity. Hla. PMID 27256587 DOI: 10.1111/tan.12822 |
0.432 |
|
2016 |
MacDonald KG, Hoeppli RE, Huang Q, Gillies J, Luciani DS, Orban PC, Broady R, Levings MK. Alloantigen-specific regulatory T cells generated with a chimeric antigen receptor. The Journal of Clinical Investigation. PMID 26999600 DOI: 10.1172/Jci82771 |
0.509 |
|
2016 |
Patterson SJ, Pesenacker AM, Wang AY, Gillies J, Mojibian M, Morishita K, Tan R, Kieffer TJ, Verchere CB, Panagiotopoulos C, Levings MK. T regulatory cell chemokine production mediates pathogenic T cell attraction and suppression. The Journal of Clinical Investigation. PMID 26854929 DOI: 10.1172/Jci83987 |
0.548 |
|
2016 |
Pesenacker AM, Wang AY, Singh A, Gillies J, Kim YW, Piccirillo CA, Nguyen D, Haining WN, Tebbutt SJ, Panagiotopoulos C, Levings MK. A Treg gene signature is a specific and sensitive biomarker to identify children with new onset type 1 diabetes. Diabetes. PMID 26786322 DOI: 10.2337/Db15-0572 |
0.452 |
|
2016 |
Dijke E, Hoeppli R, Seeberger K, Larsen I, Rebeyka I, Ross D, Korbutt G, Levings M, West L. Allogeneic and Xenogeneic Immunity Is Potently Suppressed by Expanded Regulatory T Cells (Tregs) from Human Thymus Journal of Heart and Lung Transplantation. 35. DOI: 10.1016/J.Healun.2016.01.521 |
0.577 |
|
2015 |
Weiner J, Duran-Struuck R, Zitsman J, Buhler L, Sondermeijer H, McMurchy AN, Levings MK, Sykes M, Griesemer A. Restimulation After Cryopreservation and Thawing Preserves the Phenotype and Function of Expanded Baboon Regulatory T Cells. Transplantation Direct. 1: 1-7. PMID 27019869 DOI: 10.1097/Txd.0000000000000511 |
0.527 |
|
2015 |
Dijke IE, Hoeppli RE, Ellis T, Pearcey J, Huang Q, McMurchy AN, Boer K, Peeters AM, Aubert G, Larsen I, Ross DB, Rebeyka I, Campbell A, Baan CC, Levings MK, et al. Discarded Human Thymus Is a Novel Source of Stable and Long-Lived Therapeutic Regulatory T Cells. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 26414799 DOI: 10.1111/Ajt.13456 |
0.576 |
|
2015 |
Yao Y, Vent-Schmidt J, McGeough MD, Wong M, Hoffman HM, Steiner TS, Levings MK. Tr1 Cells, but Not Foxp3+ Regulatory T Cells, Suppress NLRP3 Inflammasome Activation via an IL-10-Dependent Mechanism. Journal of Immunology (Baltimore, Md. : 1950). 195: 488-97. PMID 26056255 DOI: 10.4049/Jimmunol.1403225 |
0.526 |
|
2015 |
Han JM, Wu D, Denroche HC, Yao Y, Verchere CB, Levings MK. IL-33 Reverses an Obesity-Induced Deficit in Visceral Adipose Tissue ST2+ T Regulatory Cells and Ameliorates Adipose Tissue Inflammation and Insulin Resistance. Journal of Immunology (Baltimore, Md. : 1950). 194: 4777-83. PMID 25870243 DOI: 10.4049/Jimmunol.1500020 |
0.405 |
|
2015 |
Hoeppli RE, Wu D, Cook L, Levings MK. The environment of regulatory T cell biology: cytokines, metabolites, and the microbiome. Frontiers in Immunology. 6: 61. PMID 25741338 DOI: 10.3389/Fimmu.2015.00061 |
0.553 |
|
2015 |
MacDonald KG, Dawson NA, Huang Q, Dunne JV, Levings MK, Broady R. Regulatory T cells produce profibrotic cytokines in the skin of patients with systemic sclerosis. The Journal of Allergy and Clinical Immunology. 135: 946-.e9. PMID 25678090 DOI: 10.1016/J.Jaci.2014.12.1932 |
0.529 |
|
2015 |
Pesenacker AM, Broady R, Levings MK. Control of tissue-localized immune responses by human regulatory T cells. European Journal of Immunology. 45: 333-43. PMID 25378065 DOI: 10.1002/Eji.201344205 |
0.545 |
|
2015 |
Dijke E, Hoeppli R, Ellis T, Pearcey J, Larsen I, Rebeyka I, Ross D, Levings M, West L. Rapamycin Enhances the Suppressive Capacity of Ex Vivo Expanded Regulatory T Cells (Tregs) Isolated From Pediatric Thymus Journal of Heart and Lung Transplantation. 34. DOI: 10.1016/J.Healun.2015.01.397 |
0.517 |
|
2015 |
Guallart PA, Zitsman J, Sondermeijer H, Bühler L, Ovanez C, McMurchy A, Levings M, Sykes M, Duran-Struuck R. Phenotype, Function and Expansion of Regulatory T Cells in the Cynomolgus Macaque (Macaca fascicularis) Biology of Blood and Marrow Transplantation. 21: S280-S281. DOI: 10.1016/J.Bbmt.2014.11.445 |
0.514 |
|
2015 |
Guallart PA, Zitsman J, Sondermeijer H, Woodland D, Kato Y, Weiner J, Griesemer A, Bühler L, McMurchy A, Levings M, Sykes M, Duran-Struuck R. Induction of Durable Mixed Hematopoietic Chimerism and Immune Tolerance in Monkeys Biology of Blood and Marrow Transplantation. 21: S46-S47. DOI: 10.1016/J.Bbmt.2014.11.040 |
0.358 |
|
2014 |
Antignano F, Burrows K, Hughes MR, Han JM, Kron KJ, Penrod NM, Oudhoff MJ, Wang SK, Min PH, Gold MJ, Chenery AL, Braam MJ, Fung TC, Rossi FM, McNagny KM, ... ... Levings MK, et al. Methyltransferase G9A regulates T cell differentiation during murine intestinal inflammation. The Journal of Clinical Investigation. 124: 1945-55. PMID 24667637 DOI: 10.1172/Jci69592 |
0.507 |
|
2014 |
Han JM, Patterson SJ, Speck M, Ehses JA, Levings MK. Insulin inhibits IL-10-mediated regulatory T cell function: implications for obesity. Journal of Immunology (Baltimore, Md. : 1950). 192: 623-9. PMID 24323581 DOI: 10.4049/Jimmunol.1302181 |
0.414 |
|
2014 |
Vent-Schmidt J, Han JM, MacDonald KG, Levings MK. The role of FOXP3 in regulating immune responses. International Reviews of Immunology. 33: 110-28. PMID 23947341 DOI: 10.3109/08830185.2013.811657 |
0.47 |
|
2014 |
Dijke E, McMurchy A, Ellis T, Boer K, Larsen I, Rebeyka I, Ross D, Baan C, Levings M, West L. Pediatric Thymic Tissue as a Novel Source for the Expansion of Stable Regulatory T Cells for Cellular Therapy.: Abstract# 2273 Transplantation. 98: 43. DOI: 10.1097/00007890-201407151-00144 |
0.46 |
|
2014 |
Dijke E, McMurchy A, Ellis T, Boer K, Larsen I, Rebeyka I, Ross D, Baan C, Levings M, West L. Expanded Thymic CD25+FOXP3+ Regulatory T Cells (Tregs) Maintain Stable Function and Phenotype Under Inflammatory Conditions - Potential for Cellular Therapy? Journal of Heart and Lung Transplantation. 33. DOI: 10.1016/J.Healun.2014.01.104 |
0.516 |
|
2013 |
Han JM, Levings MK. Immune regulation in obesity-associated adipose inflammation. Journal of Immunology (Baltimore, Md. : 1950). 191: 527-32. PMID 23825387 DOI: 10.4049/Jimmunol.1301035 |
0.349 |
|
2013 |
MacDonald KG, Han JM, Himmel ME, Huang Q, Kan B, Campbell AI, Lavoie PM, Levings MK. Response to comment on "helios+ and helios- cells coexist within the natural FOXP3+ T regulatory cell subset in humans". Journal of Immunology (Baltimore, Md. : 1950). 190: 4440-1. PMID 23606719 DOI: 10.4049/Jimmunol.1390019 |
0.458 |
|
2013 |
Himmel ME, MacDonald KG, Garcia RV, Steiner TS, Levings MK. Helios+ and Helios- cells coexist within the natural FOXP3+ T regulatory cell subset in humans. Journal of Immunology (Baltimore, Md. : 1950). 190: 2001-8. PMID 23359504 DOI: 10.4049/Jimmunol.1201379 |
0.556 |
|
2013 |
McMurchy AN, Levings MK. In vitro generation of human T regulatory cells: generation, culture, and analysis of FOXP3-transduced T cells. Methods in Molecular Biology (Clifton, N.J.). 946: 115-32. PMID 23179829 DOI: 10.1007/978-1-62703-128-8_8 |
0.618 |
|
2013 |
McMurchy AN, Gillies J, Gizzi MC, Riba M, Garcia-Manteiga JM, Cittaro D, Lazarevic D, Di Nunzio S, Piras IS, Bulfone A, Roncarolo MG, Stupka E, Bacchetta R, Levings MK. A novel function for FOXP3 in humans: intrinsic regulation of conventional T cells. Blood. 121: 1265-75. PMID 23169781 DOI: 10.1182/Blood-2012-05-431023 |
0.563 |
|
2013 |
Battaglia M, Bacchetta R, Levings M, Gregori S. T-Cell-Mediated Suppression: From Bench to Bedside Blood. 122. DOI: 10.1182/Blood.V122.21.Sci-37.Sci-37 |
0.618 |
|
2013 |
Prestidge T, Davis J, Huang J, Himmel M, Levings M. Autologous transplant for autoimmune disease: optimizing the regulatory T cells Cytotherapy. 15: S42-S43. DOI: 10.1016/J.Jcyt.2013.01.161 |
0.462 |
|
2013 |
Dijke E, Levings M, McMurchy A, Larsen I, Rebeyka I, Ross D, West L. Pediatric thymic tissue as a source of CD25+FOXP3+ regulatory T cells (Tregs) for cellular therapy Cytotherapy. 15. DOI: 10.1016/J.Jcyt.2013.01.160 |
0.493 |
|
2013 |
Dijke E, McMurchy A, Levings M, Larsen I, Rebeyka I, Ross D, West L. Pediatric Thymic Tissue as a Source of Regulatory T Cells for Cellular Therapy Journal of Heart and Lung Transplantation. 32. DOI: 10.1016/J.Healun.2013.01.982 |
0.495 |
|
2012 |
Yao Y, Levings MK, Steiner TS. ATP conditions intestinal epithelial cells to an inflammatory state that promotes components of DC maturation. European Journal of Immunology. 42: 3310-21. PMID 22987503 DOI: 10.1002/Eji.201142213 |
0.459 |
|
2012 |
Han JM, Patterson SJ, Levings MK. The Role of the PI3K Signaling Pathway in CD4(+) T Cell Differentiation and Function. Frontiers in Immunology. 3: 245. PMID 22905034 DOI: 10.3389/Fimmu.2012.00245 |
0.549 |
|
2012 |
MacDonald KG, Orban PC, Levings MK. T regulatory cell therapy in transplantation: stability, localization and functional specialization. Current Opinion in Organ Transplantation. 17: 343-8. PMID 22790068 DOI: 10.1097/Mot.0B013E328355Aaaf |
0.534 |
|
2012 |
Marwaha AK, Leung NJ, McMurchy AN, Levings MK. TH17 Cells in Autoimmunity and Immunodeficiency: Protective or Pathogenic? Frontiers in Immunology. 3: 129. PMID 22675324 DOI: 10.3389/Fimmu.2012.00129 |
0.486 |
|
2012 |
Yurchenko E, Shio MT, Huang TC, Da Silva Martins M, Szyf M, Levings MK, Olivier M, Piccirillo CA. Inflammation-driven reprogramming of CD4+ Foxp3+ regulatory T cells into pathogenic Th1/Th17 T effectors is abrogated by mTOR inhibition in vivo. Plos One. 7: e35572. PMID 22545118 DOI: 10.1371/Journal.Pone.0035572 |
0.604 |
|
2012 |
Himmel ME, Yao Y, Orban PC, Steiner TS, Levings MK. Regulatory T-cell therapy for inflammatory bowel disease: more questions than answers. Immunology. 136: 115-22. PMID 22348589 DOI: 10.1111/J.1365-2567.2012.03572.X |
0.473 |
|
2012 |
McMurchy AN, Levings MK. Suppression assays with human T regulatory cells: a technical guide. European Journal of Immunology. 42: 27-34. PMID 22161814 DOI: 10.1002/Eji.201141651 |
0.6 |
|
2012 |
Hardenberg G, Yao Y, Piccirillo CA, Levings MK, Steiner TS. Toll-like receptor 5 deficiency protects from wasting disease in a T cell transfer colitis model in T cell receptor-β-deficient mice. Inflammatory Bowel Diseases. 18: 85-93. PMID 22038840 DOI: 10.1002/Ibd.21738 |
0.544 |
|
2012 |
Ivison S, Kariminia A, Levings M, Broady R, Panzarella T, Albert-Green A, Aljurf M, Al Humaidan H, Foley R, Devins G, Kerr HM, Lee SJ, Swajcer D, Toze CL, Couban S, et al. Higher Proportions of IFNg-Producing T Cells, CD56bright NK Cells and Immature B Cells in the Lymphocytes of G-CSF Stimulated Donor Grafts Are Associated with Less Chronic Gvhd After HSCT: Results From the Canadian BMT Group 0601 Randomized, Phase III Trial Blood. 120: 1944-1944. DOI: 10.1182/Blood.V120.21.1944.1944 |
0.449 |
|
2012 |
Dijke E, McMurchy A, Levings M, Larsen I, Rebeyka I, Ross D, West L. Expansion of Highly Suppressive FOXP3+ Regulatory T Cells from Pediatric Thymic Tissue: 2239 Transplantation. 94: 1193. DOI: 10.1097/00007890-201211271-00661 |
0.51 |
|
2012 |
Montane J, Obach M, Bischoff L, Soukhatcheva G, Orban PC, Hardenberg G, Levings MK, Tan R, Verchere CB. Chemokine Induced Tolerance in Mouse Islet Allografts Canadian Journal of Diabetes. 36. DOI: 10.1016/J.Jcjd.2012.07.468 |
0.344 |
|
2011 |
Cohen CJ, Crome SQ, MacDonald KG, Dai EL, Mager DL, Levings MK. Human Th1 and Th17 cells exhibit epigenetic stability at signature cytokine and transcription factor loci. Journal of Immunology (Baltimore, Md. : 1950). 187: 5615-26. PMID 22048764 DOI: 10.4049/Jimmunol.1101058 |
0.46 |
|
2011 |
Yurchenko E, Levings MK, Piccirillo CA. CD4+ Foxp3+ regulatory T cells suppress γδ T-cell effector functions in a model of T-cell-induced mucosal inflammation. European Journal of Immunology. 41: 3455-66. PMID 21956668 DOI: 10.1002/Eji.201141814 |
0.571 |
|
2011 |
Zhang X, de Chickera SN, Willert C, Economopoulos V, Noad J, Rohani R, Wang AY, Levings MK, Scheid E, Foley R, Foster PJ, Dekaban GA. Cellular magnetic resonance imaging of monocyte-derived dendritic cell migration from healthy donors and cancer patients as assessed in a scid mouse model. Cytotherapy. 13: 1234-48. PMID 21923625 DOI: 10.3109/14653249.2011.605349 |
0.329 |
|
2011 |
Assi K, Patterson S, Dedhar S, Owen D, Levings M, Salh B. Role of epithelial integrin-linked kinase in promoting intestinal inflammation: effects on CCL2, fibronectin and the T cell repertoire. Bmc Immunology. 12: 42. PMID 21806815 DOI: 10.1186/1471-2172-12-42 |
0.362 |
|
2011 |
Antignano F, Hamilton M, Patterson S, Ho V, Cohen C, Levings MK, Krystal G. SHIP-deficient dendritic cells, unlike wild type dendritic cells, suppress T cell proliferation via a nitric oxide-independent mechanism. Plos One. 6: e21893. PMID 21755007 DOI: 10.1371/Journal.Pone.0021893 |
0.475 |
|
2011 |
Montane J, Bischoff L, Soukhatcheva G, Dai DL, Hardenberg G, Levings MK, Orban PC, Kieffer TJ, Tan R, Verchere CB. Prevention of murine autoimmune diabetes by CCL22-mediated Treg recruitment to the pancreatic islets. The Journal of Clinical Investigation. 121: 3024-8. PMID 21737880 DOI: 10.1172/Jci43048 |
0.499 |
|
2011 |
McMurchy AN, Bushell A, Levings MK, Wood KJ. Moving to tolerance: clinical application of T regulatory cells. Seminars in Immunology. 23: 304-13. PMID 21620722 DOI: 10.1016/J.Smim.2011.04.001 |
0.501 |
|
2011 |
Patterson SJ, Han JM, Garcia R, Assi K, Gao T, O'Neill A, Newton AC, Levings MK. Cutting edge: PHLPP regulates the development, function, and molecular signaling pathways of regulatory T cells. Journal of Immunology (Baltimore, Md. : 1950). 186: 5533-7. PMID 21498666 DOI: 10.4049/Jimmunol.1002126 |
0.473 |
|
2011 |
Hardenberg G, Steiner TS, Levings MK. Environmental influences on T regulatory cells in inflammatory bowel disease. Seminars in Immunology. 23: 130-8. PMID 21295492 DOI: 10.1016/J.Smim.2011.01.012 |
0.543 |
|
2011 |
Himmel ME, Crome SQ, Ivison S, Piccirillo C, Steiner TS, Levings MK. Human CD4+ FOXP3+ regulatory T cells produce CXCL8 and recruit neutrophils. European Journal of Immunology. 41: 306-12. PMID 21268001 DOI: 10.1002/Eji.201040459 |
0.568 |
|
2011 |
Wang AY, Crome SQ, Jenkins KM, Medin JA, Bramson JL, Levings MK. Adenoviral-transduced dendritic cells are susceptible to suppression by T regulatory cells and promote interleukin 17 production. Cancer Immunology, Immunotherapy : Cii. 60: 381-8. PMID 21153637 DOI: 10.1007/S00262-010-0948-4 |
0.479 |
|
2011 |
Ivison SM, Himmel ME, Mayer M, Yao Y, Kifayet A, Levings MK, Steiner TS. The stress signal extracellular ATP modulates antiflagellin immune responses in intestinal epithelial cells. Inflammatory Bowel Diseases. 17: 319-33. PMID 20722064 DOI: 10.1002/Ibd.21428 |
0.34 |
|
2011 |
Assi K, Patterson S, Owen DA, Dedhar S, Levings MK, Salh B. Integrin-Linked Kinase Promotes Colitis Through Regulation of CCL2, Fibronectin and Regulatory T Cells Gastroenterology. 140: S-636. DOI: 10.1016/S0016-5085(11)62632-2 |
0.462 |
|
2011 |
Yao Y, Steiner TS, Levings MK. The Stress Signal Extracellular ATP Modulates Immune Responses in Intestinal Epithelial Cells and Influences Dendritic Cell Maturation Gastroenterology. 140. DOI: 10.1016/S0016-5085(11)62627-9 |
0.376 |
|
2011 |
Wang AY, Levings MK. T regulatory cells and cancer immunotherapy Experimental and Applied Immunotherapy. 207-228. DOI: 10.1007/978-1-60761-980-2_10 |
0.451 |
|
2010 |
McMurchy AN, Gillies J, Allan SE, Passerini L, Gambineri E, Roncarolo MG, Bacchetta R, Levings MK. Point mutants of forkhead box P3 that cause immune dysregulation, polyendocrinopathy, enteropathy, X-linked have diverse abilities to reprogram T cells into regulatory T cells. The Journal of Allergy and Clinical Immunology. 126: 1242-51. PMID 21036387 DOI: 10.1016/J.Jaci.2010.09.001 |
0.484 |
|
2010 |
Silverman JM, Clos J, Horakova E, Wang AY, Wiesgigl M, Kelly I, Lynn MA, McMaster WR, Foster LJ, Levings MK, Reiner NE. Leishmania exosomes modulate innate and adaptive immune responses through effects on monocytes and dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 185: 5011-22. PMID 20881185 DOI: 10.4049/Jimmunol.1000541 |
0.464 |
|
2010 |
Broady R, Yu J, Chow V, Tantiworawit A, Kang C, Berg K, Martinka M, Ghoreishi M, Dutz J, Levings MK. Cutaneous GVHD is associated with the expansion of tissue-localized Th1 and not Th17 cells. Blood. 116: 5748-51. PMID 20864580 DOI: 10.1182/Blood-2010-07-295436 |
0.454 |
|
2010 |
Marwaha AK, Crome SQ, Panagiotopoulos C, Berg KB, Qin H, Ouyang Q, Xu L, Priatel JJ, Levings MK, Tan R. Cutting edge: Increased IL-17-secreting T cells in children with new-onset type 1 diabetes. Journal of Immunology (Baltimore, Md. : 1950). 185: 3814-8. PMID 20810982 DOI: 10.4049/Jimmunol.1001860 |
0.537 |
|
2010 |
Crome SQ, Clive B, Wang AY, Kang CY, Chow V, Yu J, Lai A, Ghahary A, Broady R, Levings MK. Inflammatory effects of ex vivo human Th17 cells are suppressed by regulatory T cells. Journal of Immunology (Baltimore, Md. : 1950). 185: 3199-208. PMID 20720207 DOI: 10.4049/Jimmunol.1000557 |
0.567 |
|
2010 |
Ladd M, Sharma A, Huang Q, Wang AY, Xu L, Genowati I, Levings MK, Lavoie PM. Natural killer T cells constitutively expressing the interleukin-2 receptor α chain early in life are primed to respond to lower antigenic stimulation. Immunology. 131: 289-99. PMID 20545784 DOI: 10.1111/J.1365-2567.2010.03304.X |
0.544 |
|
2010 |
Maggi L, Santarlasci V, Capone M, Peired A, Frosali F, Crome SQ, Querci V, Fambrini M, Liotta F, Levings MK, Maggi E, Cosmi L, Romagnani S, Annunziato F. CD161 is a marker of all human IL-17-producing T-cell subsets and is induced by RORC. European Journal of Immunology. 40: 2174-81. PMID 20486123 DOI: 10.1002/Eji.200940257 |
0.424 |
|
2010 |
Crome SQ, Wang AY, Levings MK. Translational mini-review series on Th17 cells: Function and regulation of human T helper 17 cells in health and disease Clinical and Experimental Immunology. 159: 109-119. PMID 19912252 DOI: 10.1111/J.1365-2249.2009.04037.X |
0.563 |
|
2010 |
Ivison SM, Himmel ME, Hardenberg G, Wark PA, Kifayet A, Levings MK, Steiner TS. TLR5 is not required for flagellin-mediated exacerbation of DSS colitis. Inflammatory Bowel Diseases. 16: 401-9. PMID 19774646 DOI: 10.1002/Ibd.21097 |
0.434 |
|
2010 |
Montane J, Bischoff L, Soukhatcheva G, Hardenberg G, Levings MK, Tan R, Verchere CB. T Regulatory Cell Mediated Protection Of Allograft In Type 1 Diabetes: 2628 Transplantation. 90: 371. DOI: 10.1097/00007890-201007272-00686 |
0.422 |
|
2010 |
Himmel M, Crome S, Ivison S, Steiner T, Levings MK. Human Cd4+Foxp3+ T Regulatory Cells Produce Cxcl8 And Recruit Inflammatory Immune Cells: 3112 Transplantation. 90: 56. DOI: 10.1097/00007890-201007272-00108 |
0.568 |
|
2010 |
McMurchy A, Dai D, Gillies J, Verchere CB, Levings MK. Generation Of Human T Regulatory Cells With The Capacity To Suppress Islet Allograft Rejection In A Xenogeneic Mouse Model.: 673 Transplantation. 90: 8. DOI: 10.1097/00007890-201007272-00016 |
0.521 |
|
2010 |
Marwaha A, Levings M, Crome S, Panagiotopoulos C, Priatel J, Tan R. S.76Increased Fraction of IL-17 Secreting Cells in Type 1 Diabetes Clinical Immunology. 135. DOI: 10.1016/J.Clim.2010.03.398 |
0.316 |
|
2010 |
Crome S, Clive B, Wang A, Kang C, Chow V, Yiu J, Broady R, Levings M. The Inflammatory Effects of ex vivo Human T Helper 17 Cells are Suppressed by T Regulatory Cells Clinical Immunology. 135. DOI: 10.1016/J.Clim.2010.03.361 |
0.545 |
|
2010 |
Patterson S, Garcia R, O'Neill A, Gao T, Newton A, Levings M. PHLPP Regulates the Development, Function and Molecular Signaling Pathways of T Regulatory Cells Clinical Immunology. 135: S6. DOI: 10.1016/J.Clim.2010.03.025 |
0.441 |
|
2010 |
Broady R, Yu J, Chow V, Tantiworiwat A, Kang C, Berg K, Levings M. Patients With Cutaneous Graft Versus Host Disease Exhibit Reduced Production Of IL-17 Biology of Blood and Marrow Transplantation. 16. DOI: 10.1016/J.Bbmt.2009.12.456 |
0.309 |
|
2009 |
McMurchy AN, Levings MK. 3rd Keystone Symposium on T regulatory cells. Immunotherapy. 1: 529-37. PMID 20635985 DOI: 10.2217/Imt.09.33 |
0.519 |
|
2009 |
McMurchy AN, Di Nunzio S, Roncarolo MG, Bacchetta R, Levings MK. Molecular regulation of cellular immunity by FOXP3. Advances in Experimental Medicine and Biology. 665: 30-46. PMID 20429414 DOI: 10.1007/978-1-4419-1599-3_3 |
0.525 |
|
2009 |
Broady R, Yu J, Levings MK. ATG-induced expression of FOXP3 in human CD4(+) T cells in vitro is associated with T-cell activation and not the induction of FOXP3(+) T regulatory cells. Blood. 114: 5003-6. PMID 19822903 DOI: 10.1182/Blood-2009-04-214437 |
0.573 |
|
2009 |
Levings MK, Thomson AW. MASTering Treg function to promote tolerance. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 9: 2209-10. PMID 19764946 DOI: 10.1111/J.1600-6143.2009.02810.X |
0.359 |
|
2009 |
Di Nunzio S, Cecconi M, Passerini L, McMurchy AN, Baron U, Turbachova I, Vignola S, Valencic E, Tommasini A, Junker A, Cazzola G, Olek S, Levings MK, Perroni L, Roncarolo MG, et al. Wild-type FOXP3 is selectively active in CD4+CD25(hi) regulatory T cells of healthy female carriers of different FOXP3 mutations. Blood. 114: 4138-41. PMID 19738030 DOI: 10.1182/Blood-2009-04-214593 |
0.493 |
|
2009 |
Locke NR, Patterson SJ, Hamilton MJ, Sly LM, Krystal G, Levings MK. SHIP regulates the reciprocal development of T regulatory and Th17 cells Journal of Immunology. 183: 975-983. PMID 19542365 DOI: 10.4049/Jimmunol.0803749 |
0.547 |
|
2009 |
Crome SQ, Wang AY, Kang CY, Levings MK. The role of retinoic acid-related orphan receptor variant 2 and IL-17 in the development and function of human CD4+ T cells European Journal of Immunology. 39: 1480-1493. PMID 19449310 DOI: 10.1002/Eji.200838908 |
0.504 |
|
2008 |
Allan SE, Song-Zhao GX, Abraham T, McMurchy AN, Levings MK. Inducible reprogramming of human T cells into Treg cells by a conditionally active form of FOXP3. European Journal of Immunology. 38: 3282-9. PMID 19039775 DOI: 10.1002/Eji.200838373 |
0.568 |
|
2008 |
Broady R, Levings MK. Graft-versus-host disease: suppression by statins. Nature Medicine. 14: 1155-6. PMID 18989280 DOI: 10.1038/Nm1108-1155 |
0.308 |
|
2008 |
Himmel ME, Hardenberg G, Piccirillo CA, Steiner TS, Levings MK. The role of T-regulatory cells and Toll-like receptors in the pathogenesis of human inflammatory bowel disease. Immunology. 125: 145-53. PMID 18798918 DOI: 10.1111/J.1365-2567.2008.02939.X |
0.54 |
|
2008 |
Allan SE, Broady R, Gregori S, Himmel ME, Locke N, Roncarolo MG, Bacchetta R, Levings MK. CD4+ T-regulatory cells: toward therapy for human diseases. Immunological Reviews. 223: 391-421. PMID 18613849 DOI: 10.1111/J.1600-065X.2008.00634.X |
0.581 |
|
2008 |
Broady R, Yu J, Levings MK. Pro-tolerogenic effects of photodynamic therapy with TH9402 on dendritic cells. Journal of Clinical Apheresis. 23: 82-91. PMID 18381757 DOI: 10.1002/Jca.20162 |
0.491 |
|
2008 |
Passerini L, Allan SE, Battaglia M, Di Nunzio S, Alstad AN, Levings MK, Roncarolo MG, Bacchetta R. STAT5-signaling cytokines regulate the expression of FOXP3 in CD4+CD25+ regulatory T cells and CD4+CD25- effector T cells. International Immunology. 20: 421-31. PMID 18270368 DOI: 10.1093/Intimm/Dxn002 |
0.516 |
|
2008 |
Allan SE, Alstad AN, Merindol N, Crellin NK, Amendola M, Bacchetta R, Naldini L, Roncarolo MG, Soudeyns H, Levings MK. Generation of potent and stable human CD4+ T regulatory cells by activation-independent expression of FOXP3. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 194-202. PMID 17984976 DOI: 10.1038/Sj.Mt.6300341 |
0.591 |
|
2008 |
Broady R, Crome SQ, Yu J, Dutz JP, Levings MK. Development of a Modified Skin Explant Assay to Study Treg Suppression of Th17 Cell Mediated GvHD in the Skin Blood. 112: 5434-5434. DOI: 10.1182/Blood.V112.11.5434.5434 |
0.597 |
|
2008 |
Bacchetta R, Nunzio SD, Perroni LB, Passerini L, Allan S, Alstad A, Junker A, Levings M, Roncarolo MG. F.75. Molecular and Functional Studies in T Cells from Healthy Carriers of FOXP3 Mutations Clinical Immunology. 127. DOI: 10.1016/J.Clim.2008.03.187 |
0.377 |
|
2008 |
Crome S, Wang A, Levings M. Expression of RORC2 Controls the Development of Human Th17 Cells Clinical Immunology. 127. DOI: 10.1016/J.Clim.2008.03.043 |
0.42 |
|
2007 |
Gregori S, Bacchetta R, Passerini L, Levings MK, Roncarolo MG. Isolation, expansion, and characterization of human natural and adaptive regulatory T cells. Methods in Molecular Biology (Clifton, N.J.). 380: 83-105. PMID 17876089 DOI: 10.1007/978-1-59745-395-0_6 |
0.596 |
|
2007 |
Crellin NK, Garcia RV, Levings MK. Flow cytometry-based methods for studying signaling in human CD4+CD25+FOXP3+ T regulatory cells. Journal of Immunological Methods. 324: 92-104. PMID 17582431 DOI: 10.1016/J.Jim.2007.05.008 |
0.567 |
|
2007 |
Allan SE, Crome SQ, Crellin NK, Passerini L, Steiner TS, Bacchetta R, Roncarolo MG, Levings MK. Activation-induced FOXP3 in human T effector cells does not suppress proliferation or cytokine production. International Immunology. 19: 345-54. PMID 17329235 DOI: 10.1093/Intimm/Dxm014 |
0.571 |
|
2007 |
Crellin NK, Garcia RV, Levings MK. Altered activation of AKT is required for the suppressive function of human CD4+CD25+ T regulatory cells. Blood. 109: 2014-2022. PMID 17062729 DOI: 10.1182/Blood-2006-07-035279 |
0.47 |
|
2007 |
Crome SQ, Wang A, Levings MK. 27 Effects of IL-17 On Effector and Regultory T Cell Subsets Cytokine. 39: 8-8. DOI: 10.1016/J.Cyto.2007.07.032 |
0.48 |
|
2006 |
Levings MK, Allan S, d'Hennezel E, Piccirillo CA. Functional dynamics of naturally occurring regulatory T cells in health and autoimmunity. Advances in Immunology. 92: 119-155. PMID 17145303 DOI: 10.1016/S0065-2776(06)92003-3 |
0.537 |
|
2006 |
Gianfrani C, Levings MK, Sartirana C, Mazzarella G, Barba G, Zanzi D, Camarca A, Iaquinto G, Giardullo N, Auricchio S, Troncone R, Roncarolo MG. Gliadin-specific type 1 regulatory T cells from the intestinal mucosa of treated celiac patients inhibit pathogenic T cells. Journal of Immunology (Baltimore, Md. : 1950). 177: 4178-86. PMID 16951383 DOI: 10.4049/Jimmunol.177.6.4178 |
0.549 |
|
2006 |
Roncarolo MG, Gregori S, Battaglia M, Bacchetta R, Fleischhauer K, Levings MK. Interleukin-10-secreting type 1 regulatory T cells in rodents and humans. Immunological Reviews. 212: 28-50. PMID 16903904 DOI: 10.1111/J.0105-2896.2006.00420.X |
0.582 |
|
2006 |
Bacchetta R, Passerini L, Gambineri E, Dai M, Allan SE, Perroni L, Dagna-Bricarelli F, Sartirana C, Matthes-Martin S, Lawitschka A, Azzari C, Ziegler SF, Levings MK, Roncarolo MG. Defective regulatory and effector T cell functions in patients with FOXP3 mutations. The Journal of Clinical Investigation. 116: 1713-22. PMID 16741580 DOI: 10.1172/Jci25112 |
0.531 |
|
2006 |
Roncarolo MG, Gregori S, Battaglia M, Bacchetta R, Fleischhauer K, Levings MK. Erratum: Interleukin-10- secreting type 1 regulatory T cells in rodents and humans (Immunological Reviews (2006) 212, (28-50)) Immunological Reviews. 213. DOI: 10.1111/J.1600-065X.2006.00448.X |
0.513 |
|
2006 |
Allan S, Passerini L, Bacchetta R, Amendola M, Naldini L, Roncarolo MG, Levings M. Su.98. Defining a Role for FOXP3 in Human Cd4+ T-Cells Clinical Immunology. 119. DOI: 10.1016/J.Clim.2006.04.525 |
0.513 |
|
2006 |
Bacchetta R, Passerini L, Gambineri E, Allan S, Perroni L, Matthes-Martin S, Lawitschka A, Ziegler S, Levings M, Roncarolo MG. OR.40. Foxp3 Mutations in Children: Different Degrees of Impairment in Regulatory and Effector T-Cell Functions in Patients with Distinct Genotypes and Phenotypes Clinical Immunology. 119. DOI: 10.1016/J.Clim.2006.04.196 |
0.392 |
|
2006 |
Crellin N, Garcia R, Levings M. OR.7. Human CD4+CD25+ T Regulatory Cells Have Altered PKB Signalling Which Correlates with Suppressive Function Clinical Immunology. 119. DOI: 10.1016/J.Clim.2006.04.009 |
0.447 |
|
2005 |
Crellin NK, Garcia RV, Hadisfar O, Allan SE, Steiner TS, Levings MK. Human CD4+ T cells express TLR5 and its ligand flagellin enhances the suppressive capacity and expression of FOXP3 in CD4+CD25+ T regulatory cells. Journal of Immunology. 175: 8051-8059. PMID 16339542 DOI: 10.4049/Jimmunol.175.12.8051 |
0.513 |
|
2005 |
Allan SE, Passerini L, Bacchetta R, Crellin N, Dai M, Orban PC, Ziegler SF, Roncarolo MG, Levings MK. The role of 2 FOXP3 isoforms in the generation of human CD4+ Tregs. The Journal of Clinical Investigation. 115: 3276-84. PMID 16211090 DOI: 10.1172/Jci24685 |
0.47 |
|
2005 |
Levings MK, Roncarolo MG. Phenotypic and functional differences between human CD4+CD25+ and type 1 regulatory T cells. Current Topics in Microbiology and Immunology. 293: 303-326. PMID 15981486 DOI: 10.1007/3-540-27702-1_14 |
0.502 |
|
2005 |
Salvati VM, Mazzarella G, Gianfrani C, Levings MK, Stefanile R, De Giulio B, Iaquinto G, Giardullo N, Auricchio S, Roncarolo MG, Troncone R. Recombinant human interleukin 10 suppresses gliadin dependent T cell activation in ex vivo cultured coeliac intestinal mucosa. Gut. 54: 46-53. PMID 15591503 DOI: 10.1136/Gut.2003.023150 |
0.488 |
|
2005 |
Levings MK, Gregori S, Tresoldi E, Cazzaniga S, Bonini C, Roncarolo MG. Differentiation of Tr1 cells by immature dendritic cells requires IL-10 but not CD25+CD4+ Tr cells. Blood. 105: 1162-1169. PMID 15479730 DOI: 10.1182/Blood-2004-03-1211 |
0.581 |
|
2005 |
Guilbault B, Fairhurst M, Crellin N, Levings MK, Eaves AC, Thomas TE. A Simple Two-Step Method for the Isolation of Human CD4 + CD25 +bright / FOXP3 + Regulatory T Cells Directly from Whole Blood. Blood. 106: 2382-2382. DOI: 10.1182/Blood.V106.11.2382.2382 |
0.446 |
|
2004 |
Roncarolo MG, Gregori S, Levings M. Type 1 T regulatory cells and their relationship with CD4+CD25+ T regulatory cells. Novartis Foundation Symposium. 252: 115-27; discussion 1. PMID 14609215 |
0.498 |
|
2003 |
Roncarolo MG, Gregori S, Levings M. Type 1 T regulatory cells and their relationship with CD4+CD25+ T regulatory cells. Novartis Foundation Symposium. 252: 115-131. DOI: 10.1002/0470871628.Ch9 |
0.579 |
|
2002 |
Levings MK, Bacchetta R, Schulz U, Roncarolo MG. The Role of IL-10 and TGF-β in the Differentiation and Effector Function of T Regulatory Cells International Archives of Allergy and Immunology. 129: 263-276. PMID 12483031 DOI: 10.1159/000067596 |
0.547 |
|
2002 |
Levings MK, Sangregorio R, Sartirana C, Moschin AL, Battaglia M, Orban PC, Roncarolo M. Human CD25+CD4+ T Suppressor Cell Clones Produce Transforming Growth Factor β, but not Interleukin 10, and Are Distinct from Type 1 T Regulatory Cells Journal of Experimental Medicine. 196: 1335-1346. PMID 12438424 DOI: 10.1084/Jem.20021139 |
0.51 |
|
2002 |
Bacchetta R, Sartirana C, Levings MK, Bordignon C, Narula S, Roncarolo M. Growth and expansion of human T regulatory type 1 cells are independent from TCR activation but require exogenous cytokines. European Journal of Immunology. 32: 2237-2245. PMID 12209636 DOI: 10.1002/1521-4141(200208)32:8<2237::Aid-Immu2237>3.0.Co;2-2 |
0.459 |
|
2001 |
Roncarolo MG, Bacchetta R, Bordignon C, Narula S, Levings MK. Type 1 T regulatory cells. Immunological Reviews. 182: 68-79. PMID 11722624 DOI: 10.1034/J.1600-065X.2001.1820105.X |
0.537 |
|
2001 |
Levings MK, Sangregorio R, Roncarolo M. Human Cd25+Cd4+ T Regulatory Cells Suppress Naive and Memory T Cell Proliferation and Can Be Expanded in Vitro without Loss of Function Journal of Experimental Medicine. 193: 1295-1302. PMID 11390436 DOI: 10.1084/Jem.193.11.1295 |
0.499 |
|
2001 |
Levings MK, Sangregorio R, Galbiati F, Squadrone S, Malefyt RdW, Roncarolo M. IFN-α and IL-10 Induce the Differentiation of Human Type 1 T Regulatory Cells Journal of Immunology. 166: 5530-5539. PMID 11313392 DOI: 10.4049/Jimmunol.166.9.5530 |
0.535 |
|
2001 |
Roncarolo MG, Levings MK, Traversari C. Differentiation of T Regulatory Cells by Immature Dendritic Cells Journal of Experimental Medicine. 193. PMID 11208869 DOI: 10.1084/Jem.193.2.F5 |
0.456 |
|
2000 |
Roncarolo MG, Levings MK. The role of different subsets of T regulatory cells in controlling autoimmunity. Current Opinion in Immunology. 12: 676-683. PMID 11102772 DOI: 10.1016/S0952-7915(00)00162-X |
0.546 |
|
2000 |
Levings MK, Roncarolo M. T-regulatory 1 cells: A novel subset of CD4+ T cells with immunoregulatory properties The Journal of Allergy and Clinical Immunology. 106. PMID 10887343 DOI: 10.1067/Mai.2000.106635 |
0.587 |
|
1999 |
Levings MK, Bessette DC, Schrader JW. Interleukin-4 synergizes with Raf-1 to promote long-term proliferation and activation of c-jun N-terminal kinase Blood. 93: 3694-3702. PMID 10339476 DOI: 10.1182/Blood.V93.11.3694.411A33_3694_3702 |
0.338 |
|
1997 |
Welham MJ, Bone H, Levings M, Learmonth L, Wang LM, Leslie KB, Pierce JH, Schrader JW. Insulin receptor substrate-2 is the major 170-kDa protein phosphorylated on tyrosine in response to cytokines in murine lymphohemopoietic cells Journal of Biological Chemistry. 272: 1377-1381. PMID 8995447 DOI: 10.1074/Jbc.272.2.1377 |
0.36 |
|
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