David G. Edwards - Publications

Affiliations: 
Kinesiology & Applied Physiology University of Delaware, Newark, DE, United States 

72 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 DeConne TM, Fancher IS, Edwards DG, Trott DW, Martens CR. CD8 T-cell metabolism is related to cerebrovascular function in middle-aged adults. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. PMID 38406845 DOI: 10.1152/ajpregu.00267.2023  0.615
2023 Stock JM, Shenouda N, Chouramanis NV, Patik JC, Martens CR, Farquhar WB, Chirinos JA, Edwards DG. The Effect of Acute Handgrip and Aerobic Exercise on Wasted Pressure Effort and Arterial Wave Reflections in Healthy Aging. American Journal of Physiology. Heart and Circulatory Physiology. PMID 37477688 DOI: 10.1152/ajpheart.00133.2023  0.658
2021 Kirkman DL, Robinson AT, Rossman MJ, Seals DR, Edwards DG. Mitochondrial Contributions to Vascular Endothelial Dysfunction, Arterial Stiffness and Cardiovascular Diseases. American Journal of Physiology. Heart and Circulatory Physiology. PMID 33834868 DOI: 10.1152/ajpheart.00917.2020  0.437
2021 Coyle PC, O'Brien VA, Edwards DG, Pohlig RT, Hicks GE. Markers of Cardiovascular Health in Older Adults with and Without Chronic Low Back and Radicular Leg Pain: A Comparative Analysis. Pain Medicine (Malden, Mass.). PMID 33585935 DOI: 10.1093/pm/pnaa426  0.507
2020 Stock JM, Chouramanis NV, Chirinos JA, Edwards DG. Dynamic and isometric handgrip exercise increases wave reflection in healthy young adults. Journal of Applied Physiology (Bethesda, Md. : 1985). 129: 709-717. PMID 32853105 DOI: 10.1152/Japplphysiol.00281.2020  0.32
2020 Kuczmarski AV, Shoemaker LN, Hobson JC, Edwards DG, Wenner MM. Altered endothelial ET receptor expression in postmenopausal women. American Journal of Physiology. Heart and Circulatory Physiology. PMID 32559137 DOI: 10.1152/Ajpheart.00342.2020  0.328
2020 Babcock MC, Robinson AT, Migdal KU, Watso JC, Martens CR, Edwards DG, Pescatello LS, Farquhar WB. High Salt Intake Augments Blood Pressure Responses During Submaximal Aerobic Exercise. Journal of the American Heart Association. e015633. PMID 32406312 DOI: 10.1161/Jaha.120.015633  0.69
2020 Shenouda N, Ramick MG, Lennon SL, Farquhar WB, Edwards DG. High dietary sodium augments vascular tone and attenuates low-flow mediated constriction in salt-resistant adults. European Journal of Applied Physiology. PMID 32306153 DOI: 10.1007/S00421-020-04370-0  0.316
2020 Nathaniel SD, McGinty S, Edwards DG, Farquhar WB, Witman MAH, Hosmane V, Wenner MM. Effects Of Angiotensin Receptor Neprilysin Inhibition On Blood Pressure Response To Exercise In Heart Failure Medicine & Science in Sports & Exercise. 52: 227-227. DOI: 10.1249/01.Mss.0000676020.36888.E5  0.33
2020 Nathaniel SD, McGinty S, Edwards DG, Farquhar WB, Witman MA, Hosmane V, Wenner MM. Abstract P097: Angiotensin Receptor Neprilysin Inhibition Improves Arterial Stiffness And Endothelial Function In Heart Failure With Reduced Ejection Fraction Hypertension. 76. DOI: 10.1161/Hyp.76.Suppl_1.P097  0.329
2020 Stock JM, Chouraminis NV, Shenouda N, Patik JC, Martens CR, Farquhar WB, Chirinos JA, Edwards D. Assessment of Pulsatile Load During Lower Body Aerobic Exercise in Young and Older Adults The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.01938  0.649
2019 Babcock MC, Robinson AT, Watso JC, Migdal KU, Martens CR, Edwards DG, Pescatello LS, Farquhar WB. Salt Loading Blunts Central and Peripheral Postexercise Hypotension. Medicine and Science in Sports and Exercise. PMID 31609296 DOI: 10.1249/Mss.0000000000002187  0.643
2019 Guers JJ, Farquhar WB, Edwards DG, Lennon SL. Voluntary Wheel Running Attenuates Salt-Induced Vascular Stiffness Independent of Blood Pressure. American Journal of Hypertension. PMID 31401651 DOI: 10.1093/Ajh/Hpz128  0.325
2019 Ramick MG, Brian MS, Matthews EL, Patik JC, Seals DR, Lennon SL, Farquhar WB, Edwards DG. Apocynin and Tempol Ameliorate Dietary Sodium-Induced Declines in Cutaneous Microvascular Function in Salt Resistant Humans. American Journal of Physiology. Heart and Circulatory Physiology. PMID 31074652 DOI: 10.1152/Ajpheart.00786.2018  0.514
2019 Katulka EK, Hirt AE, Kirkman DL, Edwards DG, Witman MAH. Altered vascular function in chronic kidney disease: evidence from passive leg movement. Physiological Reports. 7: e14075. PMID 31016878 DOI: 10.14814/Phy2.14075  0.39
2019 Kirkman DL, Ramick MG, Muth BJ, Stock JM, Pohlig RT, Townsend RT, Edwards DG. The Effects of Aerobic Exercise on Vascular Function in Non-Dialysis Chronic Kidney Disease: A Randomized Controlled Trial. American Journal of Physiology. Renal Physiology. PMID 30810061 DOI: 10.1152/Ajprenal.00539.2018  0.647
2019 Guers JJ, Kasecky-Lardner L, Farquhar WB, Edwards DG, Lennon SL. Voluntary wheel running prevents salt-induced endothelial dysfunction: role of oxidative stress. Journal of Applied Physiology (Bethesda, Md. : 1985). 126: 502-510. PMID 30571282 DOI: 10.1152/Japplphysiol.00421.2018  0.396
2019 Babcock MC, Robinson AT, Watso JC, Migdal KU, Martens CR, Edwards DG, Pescatello LS, Farquhar WB. The Effect of Sodium Supplementation on Postexercise Hypotension Following Acute Submaximal Aerobic Exercise Medicine & Science in Sports & Exercise. 51: 251-252. DOI: 10.1249/01.Mss.0000561261.22472.48  0.672
2018 Sebzda KN, Kuczmarski AV, Pohlig RT, Lennon SL, Edwards DG, Wenner MM. Ovarian Hormones Modulate Endothelin-1 Receptor Responses in Young Women. Microcirculation (New York, N.Y. : 1994). e12490. PMID 29999581 DOI: 10.1111/micc.12490  0.494
2018 Kirkman DL, Muth BJ, Stock JM, Townsend RR, Edwards DG. Cardiopulmonary exercise testing reveals subclinical abnormalities in chronic kidney disease. European Journal of Preventive Cardiology. 2047487318777777. PMID 29808762 DOI: 10.1177/2047487318777777  0.387
2018 Stock JM, Edwards DG. The Effect of Lower Body Aerobic Exercise on Forward and Backward Pressure Wave Amplitude Medicine & Science in Sports & Exercise. 50: 547. DOI: 10.1249/01.Mss.0000536891.40472.A5  0.303
2018 Kirkman DL, Muth BJ, Stock JM, Edwards DG. Aerobic Exercise Improves Subclinical Cardiopulmonary Abnormalities in Chronic Kidney Disease Medicine & Science in Sports & Exercise. 50: 422. DOI: 10.1249/01.Mss.0000536477.42968.0F  0.376
2018 Ramick MG, Kirkman DL, Stock JM, Muth BJ, Edwards DG. The Effect of Dietary Nitrates on Exercise Capacity in Chronic Kidney Disease Medicine & Science in Sports & Exercise. 50: 421. DOI: 10.1249/01.Mss.0000536472.12474.12  0.378
2018 Katulka EK, Hirt AE, Kirkman DL, Edwards DG, Witman MAH. Altered Vascular Function in Chronic Kidney Disease: Evidence from Passive Leg Movement 673 Board #8 May 30 3 15 PM - 5 15 PM Medicine and Science in Sports and Exercise. 50: 145. DOI: 10.1249/01.Mss.0000535561.25071.F6  0.316
2017 Kirkman DL, Muth BJ, Ramick MG, Townsend RR, Edwards DG. THE ROLE OF MITOCHONDRIA DERIVED REACTIVE OXYGEN SPECIES IN MICROVASCULAR DYSFUNCTION IN CHRONIC KIDNEY DISEASE. American Journal of Physiology. Renal Physiology. ajprenal.00321.2017. PMID 29117995 DOI: 10.1152/Ajprenal.00321.2017  0.367
2017 Muth BJ, Brian MS, Chirinos JA, Lennon SL, Farquhar WB, Edwards DG. Central systolic blood pressure and aortic stiffness response to dietary sodium in young and middle-aged adults. Journal of the American Society of Hypertension : Jash. PMID 28830669 DOI: 10.1016/J.Jash.2017.07.010  0.32
2017 Matthews EL, Brian MS, Edwards DG, Stocker SD, Wenner MM, Farquhar WB. Blood pressure responses to dietary sodium: Association with autonomic cardiovascular function in normotensive adults. Autonomic Neuroscience : Basic & Clinical. PMID 28802637 DOI: 10.1016/J.Autneu.2017.08.001  0.339
2017 Wenner MM, Sebzda KN, Kuczmarski AV, Pohlig RT, Edwards DG. ETB Receptor Contribution to Vascular Dysfunction in Postmenopausal Women. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. ajpregu.00410.2016. PMID 28438762 DOI: 10.1152/Ajpregu.00410.2016  0.585
2016 Guers JJ, Prisby RD, Edwards DG, Lennon-Edwards SL. INTERMITTENT PARATHYROID HORMONE ADMINISTRATION ATTENUATES ENDOTHELIAL DYSFUNCTION IN OLD RATS. Journal of Applied Physiology (Bethesda, Md. : 1985). jap.00348.2016. PMID 27815368 DOI: 10.1152/Japplphysiol.00348.2016  0.36
2016 Kirkman DL, Muth BJ, Edwards DG. Cardiopulmonary Exercise Testing Reveals Abnormalities in Chronic Kidney Disease: 2576 Board #99 June 3, 9: 30 AM - 11: 00 AM. Medicine and Science in Sports and Exercise. 48: 714. PMID 27361212 DOI: 10.1249/01.Mss.0000487145.29977.4E  0.364
2016 Matthews EL, Brian MS, Coyle DE, Edwards DG, Stocker SD, Wenner MM, Farquhar WB. Peripheral Venous Distension Elicits a Blood Pressure Raising Reflex in Young and Middle-Aged Adults. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. ajpregu.00438.2015. PMID 27053648 DOI: 10.1152/Ajpregu.00438.2015  0.313
2015 Martens CR, Kirkman DL, Edwards DG. The Vascular Endothelium in Chronic Kidney Disease: A Novel Target For Aerobic Exercise. Exercise and Sport Sciences Reviews. PMID 26509484 DOI: 10.1249/Jes.0000000000000065  0.709
2015 Matthews EL, Brian MS, Ramick MG, Lennon-Edwards S, Edwards DG, Farquhar WB. High dietary sodium reduces brachial artery flow-mediated dilation in humans with salt-sensitive and salt-resistant blood pressure. Journal of Applied Physiology (Bethesda, Md. : 1985). 118: 1510-5. PMID 26078434 DOI: 10.1152/Japplphysiol.00023.2015  0.337
2015 Farquhar WB, Edwards DG, Jurkovitz CT, Weintraub WS. Dietary sodium and health: more than just blood pressure. Journal of the American College of Cardiology. 65: 1042-50. PMID 25766952 DOI: 10.1016/J.Jacc.2014.12.039  0.324
2015 Greaney JL, Edwards DG, Fadel PJ, Farquhar WB. Rapid onset pressor and sympathetic responses to static handgrip in older hypertensive adults. Journal of Human Hypertension. 29: 402-8. PMID 25471615 DOI: 10.1038/Jhh.2014.106  0.309
2014 Kirkman DL, Lennon-Edwards S, Edwards DG. Patient Education. The importance of exercise for chronic kidney disease patients. Journal of Renal Nutrition : the Official Journal of the Council On Renal Nutrition of the National Kidney Foundation. 24: e51-3. PMID 25443547 DOI: 10.1053/J.Jrn.2014.07.012  0.337
2014 Kuczmarski JM, Martens CR, Kim J, Lennon-Edwards SL, Edwards DG. Cardiac function is preserved following 4 weeks of voluntary wheel running in a rodent model of chronic kidney disease. Journal of Applied Physiology (Bethesda, Md. : 1985). 117: 482-91. PMID 25059238 DOI: 10.1152/Japplphysiol.00344.2014  0.768
2014 Martens CR, Kuczmarski JM, Kim J, Guers JJ, Harris MB, Lennon-Edwards S, Edwards DG. Voluntary wheel running augments aortic l-arginine transport and endothelial function in rats with chronic kidney disease. American Journal of Physiology. Renal Physiology. 307: F418-26. PMID 24966085 DOI: 10.1152/Ajprenal.00014.2014  0.769
2014 Lennon-Edwards S, Allman BR, Schellhardt TA, Ferreira CR, Farquhar WB, Edwards DG. Lower potassium intake is associated with increased wave reflection in young healthy adults. Nutrition Journal. 13: 39. PMID 24775098 DOI: 10.1186/1475-2891-13-39  0.304
2014 DuPont JJ, Ramick MG, Farquhar WB, Townsend RR, Edwards DG. NADPH oxidase-derived reactive oxygen species contribute to impaired cutaneous microvascular function in chronic kidney disease American Journal of Physiology - Renal Physiology. 306: F1499-F1506. PMID 24761000 DOI: 10.1152/Ajprenal.00058.2014  0.618
2014 Greaney JL, Matthews EL, Boggs ME, Edwards DG, Duncan RL, Farquhar WB. Exaggerated exercise pressor reflex in adults with moderately elevated systolic blood pressure: role of purinergic receptors. American Journal of Physiology. Heart and Circulatory Physiology. 306: H132-41. PMID 24163081 DOI: 10.1152/Ajpheart.00575.2013  0.366
2014 Kuczmarski JM, Martens CR, Lennon-Edwards SL, Edwards DG. Cardiac function and tolerance to ischemia-reperfusion injury in chronic kidney disease. Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. 29: 1514-24. PMID 24151020 DOI: 10.1093/Ndt/Gft336  0.76
2014 Martens CR, Kuczmarski JM, Lennon-Edwards S, Edwards DG. Impaired L-arginine uptake but not arginase contributes to endothelial dysfunction in rats with chronic kidney disease. Journal of Cardiovascular Pharmacology. 63: 40-8. PMID 24084210 DOI: 10.1097/Fjc.0000000000000022  0.759
2013 Greaney JL, Schwartz CE, Edwards DG, Fadel PJ, Farquhar WB. The neural interaction between the arterial baroreflex and muscle metaboreflex is preserved in older men. Experimental Physiology. 98: 1422-31. PMID 23733520 DOI: 10.1113/Expphysiol.2013.073189  0.315
2013 DuPont JJ, Greaney JL, Wenner MM, Lennon-Edwards SL, Sanders PW, Farquhar WB, Edwards DG. High dietary sodium intake impairs endothelium-dependent dilation in healthy salt-resistant humans. Journal of Hypertension. 31: 530-6. PMID 23263240 DOI: 10.1097/Hjh.0B013E32835C6Ca8  0.607
2012 Greaney JL, DuPont JJ, Lennon-Edwards SL, Sanders PW, Edwards DG, Farquhar WB. Dietary sodium loading impairs microvascular function independent of blood pressure in humans: role of oxidative stress. The Journal of Physiology. 590: 5519-28. PMID 22907057 DOI: 10.1113/Jphysiol.2012.236992  0.617
2011 Edwards DG. Exercise and diseased kidneys: are they compatible? The Journal of Physiology. 589: 5897. PMID 22174132 DOI: 10.1113/Jphysiol.2011.222646  0.402
2011 Dupont JJ, Farquhar WB, Townsend RR, Edwards DG. Ascorbic acid or L-arginine improves cutaneous microvascular function in chronic kidney disease. Journal of Applied Physiology (Bethesda, Md. : 1985). 111: 1561-7. PMID 21885796 DOI: 10.1152/Japplphysiol.00419.2011  0.623
2011 Kuczmarski JM, Darocki MD, DuPont JJ, Sikes RA, Cooper CR, Farquhar WB, Edwards DG. Effect of moderate-to-severe chronic kidney disease on flow-mediated dilation and progenitor cells. Experimental Biology and Medicine (Maywood, N.J.). 236: 1085-92. PMID 21791552 DOI: 10.1258/Ebm.2011.011008  0.735
2011 Martens CR, Edwards DG. Peripheral vascular dysfunction in chronic kidney disease. Cardiology Research and Practice. 2011: 267257. PMID 21637718 DOI: 10.4061/2011/267257  0.696
2011 Wenner MM, Edwards DG, Ray CA, Rose WC, Gardner TJ, Stillabower M, Farquhar WB. Celecoxib does not alter cardiovascular and renal function during dietary salt loading. Clinical and Experimental Pharmacology & Physiology. 38: 543-9. PMID 21631568 DOI: 10.1111/J.1440-1681.2011.05546.X  0.319
2011 DuPont JJ, Farquhar WB, Edwards DG. Intradermal microdialysis of hypertonic saline attenuates cutaneous vasodilatation in response to local heating. Experimental Physiology. 96: 674-80. PMID 21571814 DOI: 10.1113/Expphysiol.2011.058404  0.59
2010 Delaney EP, Greaney JL, Edwards DG, Rose WC, Fadel PJ, Farquhar WB. Exaggerated sympathetic and pressor responses to handgrip exercise in older hypertensive humans: role of the muscle metaboreflex. American Journal of Physiology. Heart and Circulatory Physiology. 299: H1318-27. PMID 20802135 DOI: 10.1152/Ajpheart.00556.2010  0.34
2010 Martens CR, Edwards DG, Kenefick RW. The Effect of Prolonged Exercise in the Heat and Subsequent Submaximal Exercise on Markers of Oxidative Stress Medicine & Science in Sports & Exercise. 42: 277-278. DOI: 10.1249/01.Mss.0000384371.13414.F1  0.666
2007 Heffernan KS, Edwards DG, Rossow L, Jae SY, Fernhall B. External mechanical compression reduces regional arterial stiffness. European Journal of Applied Physiology. 101: 735-41. PMID 17849144 DOI: 10.1007/S00421-007-0550-4  0.309
2007 Pierce GL, Magyari PM, Aranda JM, Edwards DG, Hamlin SA, Hill JA, Braith RW. Effect of heart transplantation on skeletal muscle metabolic enzyme reserve and fiber type in end-stage heart failure patients. Clinical Transplantation. 21: 94-100. PMID 17302597 DOI: 10.1111/J.1399-0012.2006.00589.X  0.556
2005 Edwards DG, Lang JT. Augmentation index and systolic load are lower in competitive endurance athletes. American Journal of Hypertension. 18: 679-83. PMID 15882551 DOI: 10.1016/J.Amjhyper.2004.11.028  0.335
2005 Braith RW, Magyari PM, Pierce GL, Edwards DG, Hill JA, White LJ, Aranda JM. Effect of resistance exercise on skeletal muscle myopathy in heart transplant recipients. The American Journal of Cardiology. 95: 1192-8. PMID 15877992 DOI: 10.1016/J.Amjcard.2005.01.048  0.597
2004 Edwards DG, Schofield RS, Magyari PM, Nichols WW, Braith RW. Effect of exercise training on central aortic pressure wave reflection in coronary artery disease. American Journal of Hypertension. 17: 540-3. PMID 15177529 DOI: 10.1016/J.Amjhyper.2003.12.001  0.59
2004 Edwards DG, Schofield RS, Lennon SL, Pierce GL, Nichols WW, Braith RW. Effect of exercise training on endothelial function in men with coronary artery disease. The American Journal of Cardiology. 93: 617-20. PMID 14996592 DOI: 10.1016/J.Amjcard.2003.11.032  0.625
2003 Schofield RS, Edwards DG, Schuler BT, Estrada J, Aranda JM, Pauly DF, Hill JA, Aggarwal R, Nichols WW. Vascular effects of sildenafil in hypertensive cardiac transplant recipients. American Journal of Hypertension. 16: 874-7. PMID 14553969 DOI: 10.1016/S0895-7061(03)01006-9  0.312
2003 Braith RW, Edwards DG. Neurohormonal abnormalities in heart failure: impact of exercise training. Congestive Heart Failure (Greenwich, Conn.). 9: 70-6. PMID 12671337 DOI: 10.1111/J.1527-5299.2003.00277.X  0.61
2003 Wasserman MA, Sundell CL, Kunsch C, Edwards D, Meng CQ, Medford RM. Chemistry and Pharmacology of Vascular Protectants: A Novel Approach to the Treatment of Atherosclerosis and Coronary Artery Disease American Journal of Cardiology. 91: 34-40. PMID 12645642 DOI: 10.1016/S0002-9149(02)03148-X  0.31
2003 Magyari PM, Aranda JM, Edwards DG, Pierce GL, Shanely RA, Braith RW. INCREASED MUSCULAR STRENGTH AND ENZYMATIC RESERVE FOLLOWING 4 MONTHS OF RESISTANCE TRAINING IN HEART TRANSPLANT RECIPIENTS Medicine & Science in Sports & Exercise. 35: S231. DOI: 10.1097/00005768-200305001-01286  0.558
2003 Edwards DG, Nichols WW, Schofield RS, Braith RW. EFFECTS OF EXERCISE TRAINING ON THE AMPLITUDE AND TIMING OF CENTRAL AORTIC PRESSURE WAVE REFLECTION IN CORONARY ARTERY DISEASE Medicine & Science in Sports & Exercise. 35: S119. DOI: 10.1097/00005768-200305001-00646  0.589
2003 Estrada J, Aggarwal R, Edwards DG, Schuler BT, Schofield RS, Aranda JM, Hill JA, Nichols WW. Sildenafil improves endothelial dysfunction in treated hypertensive heart transplant recipients Journal of the American College of Cardiology. 41: 280-281. DOI: 10.1016/S0735-1097(03)82317-3  0.312
2003 Edwards DG, Schofield RS, Lennon SL, Magyari PM, Pierce GL, Nichols WW, Braith RW. The effect of exercise training on endothelial function in coronary artery disease: Role of nitric oxide and endogenous antioxidants Journal of the American College of Cardiology. 41: 262-263. DOI: 10.1016/S0735-1097(03)82233-7  0.613
2002 Edwards DG, Davis M, Brubaker PH, Phillips T, Leeuwenburgh C, Braith RW. MARKERS OF INFLAMMATION ARE MODIFIED BY EXERCISE TRAINING IN CORONARY ARTERY DISEASE Medicine & Science in Sports & Exercise. 34: S180. DOI: 10.1097/00005768-200205001-01006  0.326
2001 Nichols WW, Edwards DG. Arterial elastance and wave reflection augmentation of systolic blood pressure: deleterious effects and implications for therapy. Journal of Cardiovascular Pharmacology and Therapeutics. 6: 5-21. PMID 11452332 DOI: 10.1177/107424840100600102  0.314
2001 Braith RW, Edwards DG. Exercise following heart transplantation. Sports Medicine (Auckland, N.Z.). 30: 171-92. PMID 10999422 DOI: 10.2165/00007256-200030030-00003  0.616
2001 Braith RW, Fulton MN, Edwards DG, Lisor C, Hill JA. RESISTANCE EXERCISE PLUS ALENDRONATE REVERSES STEROIDINDUCED OSTEOPOROSIS IN HEART TRANSPLANT RECIPIENTS Medicine & Science in Sports & Exercise. 33: S276. DOI: 10.1097/00005768-200105001-01556  0.586
2000 Braith RW, Howard C, Fricker FJ, Mitchell M, Edwards DG. Glucocorticoid-induced osteopenia in adolescent heart transplant recipients. The Journal of Heart and Lung Transplantation : the Official Publication of the International Society For Heart Transplantation. 19: 840-5. PMID 11008072 DOI: 10.1016/S1053-2498(00)00159-5  0.547
Show low-probability matches.