William R. Clark, Ph.D - Publications

Affiliations: 
Biology and Molecular Biology Institute University of California, Los Angeles, Los Angeles, CA 

42 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
1999 Matloubian M, Suresh M, Glass A, Galvan M, Chow K, Whitmire JK, Walsh CM, Clark WR, Ahmed R. A role for perforin in downregulating T-cell responses during chronic viral infection Journal of Virology. 73: 2527-2536. PMID 9971838 DOI: 10.1128/Jvi.73.3.2527-2536.1999  0.657
1998 Jensen ER, Glass AA, Clark WR, Wing EJ, Miller JF, Gregory SH. Fas (CD95)-dependent cell-mediated immunity to Listeria monocytogenes Infection and Immunity. 66: 4143-4150. PMID 9712760 DOI: 10.1128/Iai.66.9.4143-4150.1998  0.382
1996 Glass A, Walsh CM, Lynch DH, Clark WR. Regulation of the Fas lytic pathway in cloned CTL Journal of Immunology. 156: 3638-3644. PMID 8621897  0.594
1996 Walsh CM, Hayashi F, Saffran DC, Ju ST, Berke G, Clark WR. Cell-mediated cytotoxicity results from, but may not be critical for, primary allograft rejection Journal of Immunology. 156: 1436-1441. PMID 8568245  0.628
1996 Clark WR, Walsh CM, Matloubian M, Glass AA, Hayashi F. Mechanisms of CTL-mediated cytoxicity Seminars in Virology. 7: 113-116. DOI: 10.1006/Smvy.1996.0014  0.669
1995 Liu CC, Walsh CM, Eto N, Clark WR, Young JDE. Morphologic and functional characterization of perforin-deficient lymphokine-activated killer cells Journal of Immunology. 155: 602-608. PMID 7608538  0.663
1995 Chiu VK, Walsh CM, Liu CC, Reed JC, Clark WR. Bcl-2 blocks degranulation but not fas-based cell-mediated cytotoxicity Journal of Immunology. 154: 2023-2032. PMID 7532659  0.642
1995 Clark WR, Walsh CM, Glass AA, Huang MTF, Ahmed R, Matloubian M. Cell-mediated cytotoxicity in perforin-less mice International Reviews of Immunology. 13: 1-14. PMID 7494105 DOI: 10.3109/08830189509061734  0.667
1995 Clark WR, Walsh CM, Glass AA, Hayashi F, Matloubian M, Ahmed R. Molecular pathways of CTL-mediated cytotoxicity Immunological Reviews. 32-44. PMID 7493758 DOI: 10.1111/J.1600-065X.1995.Tb00682.X  0.602
1994 Walsh CM, Matloubian M, Liu CC, Ueda R, Kurahara CG, Christensen JL, Huang MT, Young JD, Ahmed R, Clark WR. Immune function in mice lacking the perforin gene. Proceedings of the National Academy of Sciences of the United States of America. 91: 10854-8. PMID 7526382 DOI: 10.1073/Pnas.91.23.10854  0.688
1994 Walsh CM, Glass AA, Chiu V, Clark WR. The role of the fas lytic pathway in a perforin-less CTL hybridoma Journal of Immunology. 153: 2506-2514. PMID 7521365  0.635
1991 Ratner A, Clark WR. Lack of target cell participation in cytotoxic T lymphocyte-mediated lysis Journal of Immunology. 147: 55-59. PMID 1828826  0.327
1990 Joag SV, Liu CC, Kwon BS, Clark WR, Young JDE. Expression of mRNAs for pore-forming protein and two serine esterases in murine primary and cloned effector lymphocytes Journal of Cellular Biochemistry. 43: 81-88. PMID 2347877 DOI: 10.1002/Jcb.240430108  0.304
1988 Ostergaard H, Gorman K, Clark WR. Cloned cytotoxic T lymphocyte target cells fail to induce early activation events in effector cytotoxic T lymphocytes Cellular Immunology. 114: 188-197. PMID 3259474 DOI: 10.1016/0008-8749(88)90265-1  0.413
1988 Torbett BE, Clark WR. The role of accessory molecules in T-helper activation induced by antigen, lectin, or CD3 antibodies Cellular Immunology. 115: 352-362. PMID 2970307 DOI: 10.1016/0008-8749(88)90187-6  0.353
1988 Clark WR. Perforin - a primary pr auxiliary lytic mechanism? Trends in Immunology. 9: 104-107. DOI: 10.1016/0167-5699(88)91277-7  0.358
1987 Blakely A, Gorman K, Ostergaard H, Svoboda K, Liu CC, Young JD, Clark WR. Resistance of cloned cytotoxic T lymphocytes to cell-mediated cytotoxicity. The Journal of Experimental Medicine. 166: 1070-83. PMID 3498787 DOI: 10.1084/Jem.166.4.1070  0.39
1987 Ostergaard HL, Kane KP, Mescher MF, Clark WR. Cytotoxic T lymphocyte mediated lysis without release of serine esterase Nature. 330: 71-72. PMID 3118212 DOI: 10.1038/330071A0  0.343
1986 Kane KP, Clark WR. Class I MHC antigens in the generation and expression of promiscuous cytotoxic cell function Journal of Immunology. 137: 3080-3086. PMID 3490509  0.312
1986 Brunet JF, Dosseto M, Denizot F, Mattei MG, Clark WR, Haqqi TM, Ferrier P, Nabholz M, Schmitt-Verhulst AM, Luciani MF, Golstein P. The inducible cytotoxic T-lymphocyte-associated gene transcript CTLA-1 sequence and gene localization to mouse chromosome 14. Nature. 322: 268-71. PMID 3090449 DOI: 10.1038/322268A0  0.387
1986 Torbett BE, Skidmore B, Clark WR. Multiple pathways for antigen-independent activation of a T helper hybridoma European Journal of Immunology. 16: 933-938. PMID 2943596 DOI: 10.1002/Eji.1830160810  0.358
1982 Berke G, Clark WR. T lymphocyte-mediated cytolysis - a comprehensive theory. I. The mechanism of CTL-mediated cytolysis Advances in Experimental Medicine and Biology. 146: 57-68. PMID 6980576 DOI: 10.1007/978-1-4684-8959-0_4  0.366
1982 Clark WR, Berke G. T lymphocyte-mediated cytolysis - a comprehensive theory. II. Lytic vs. nonlytic interactions of T lymphocytes Advances in Experimental Medicine and Biology. 146: 69-79. PMID 6179406 DOI: 10.1007/978-1-4684-8959-0_5  0.42
1981 Berke G, McVey E, Hu V, Clark WR. T lymphocyte-mediated cytolysis. II. Role of target cell histocompatibility antigens in recognition and lysis Journal of Immunology. 127: 782-787. PMID 6265557  0.321
1979 Clark W, Gill R. Effect Of Membrane Lipid Composition On Immune Cell Function Cell Biology and Immunology of Leukocyte Function. 613-619. DOI: 10.1016/B978-0-12-569650-0.50081-4  0.415
1978 Mandel G, Shimizu S, Gill R, Clark W. Alteration of the fatty acid composition of membrane phospholipids in mouse lymphoid cells. Journal of Immunology (Baltimore, Md. : 1950). 120: 1631-6. PMID 659868  0.494
1978 Mandel G, Clark W. Functional properties of EL-4 tumor cells with lipid-altered membranes. Journal of Immunology (Baltimore, Md. : 1950). 120: 1637-43. PMID 351054  0.52
1978 Kedar E, Clark WR, Bonavida B. In vivo and in vitro induction of cytotoxic lymphocytes by alloantigen-reactive lymphocytes fractionated on spleen cell monolayers Transplantation. 25: 146-151. PMID 306147  0.323
1978 Touton M, Clark WR. Progressive changes in cytotoxic potential during mixed lymphocyte culture Journal of Immunology. 120: 1537-1543. PMID 149172  0.328
1978 Clark WR. Ontogeny of T cell function: Generation of cytotoxic function in T cells as a model for terminal cell differentiation Developmental and Comparative Immunology. 2: 393-407. PMID 80334 DOI: 10.1016/S0145-305X(78)80002-0  0.373
1977 Chakravarty AK, Clark WR. Lectin driven maturation of cytotoxic effector cells: the nature of effector memory Journal of Experimental Medicine. 146: 230-240. PMID 301545 DOI: 10.1084/Jem.146.1.230  0.36
1977 Knoeber LL, Clark W. Temporal requirement for antigen in primary and secondary mlc reactions Transplantation. 24: 10-15. PMID 142322 DOI: 10.1097/00007890-197707000-00003  0.323
1977 Clark WR, Heininger D, Touton M, Chakravarty AK. Regeneration Of Effector Function In Vitro Regulatory Mechanisms in Lymphocyte Activation. 650-652. DOI: 10.1016/B978-0-12-458050-3.50117-X  0.355
1976 Heininger D, Touton M, Chakravarty AK, Clark WR. Activation of cytotoxic function in T lymphocytes Journal of Immunology. 117: 2175-2180. PMID 136475  0.321
1975 Clark WR. An antigen-specific component of lectin-mediated cytotoxicity Cellular Immunology. 17: 505-516. PMID 1125996 DOI: 10.1016/S0008-8749(75)80054-2  0.455
1975 Nedrud J, Touton M, Clark WR. The requirement for DNA synthesis and gene expression in the generation of cytotoxicity in vitro Journal of Experimental Medicine. 142: 960-973. PMID 127017 DOI: 10.1084/Jem.142.4.960  0.371
1974 Kimura AK, Clark WR. Functional characteristics of T cell receptors during sensitization against histocompatibility antigens in vitro Cellular Immunology. 12: 127-139. PMID 4282067 DOI: 10.1016/0008-8749(74)90064-1  0.392
1972 Clark WR, Rutter WJ. Synthesis and accumulation of insulin in the fetal rat pancreas Developmental Biology. 29: 468-481. PMID 4570760 DOI: 10.1016/0012-1606(72)90084-X  0.419
1972 Pictet RL, Clark WR, Williams RH, Rutter WJ. An ultrastructural analysis of the developing embryonic pancreas Developmental Biology. 29: 436-467. PMID 4570759 DOI: 10.1016/0012-1606(72)90083-8  0.518
1972 Clark W, Kimura A. Immunoreactivity in a cellular immune reaction of lymphocytes preabsorbed on cell monolayers Nature: New Biology. 235: 236-238. PMID 4502412 DOI: 10.1038/Newbio235236A0  0.345
1971 Berke G, Clark WR, Feldman M. In vitro induction of a heterograft reaction: Immunological parameters of the sensitization of rat lymphocytes against mouse cells in vitro Transplantation. 12: 237-248. PMID 4398839 DOI: 10.1097/00007890-197110000-00001  0.333
1968 Rutter WJ, Kemp JD, Bradshaw WS, Clark WR, Ronzio RA, Sanders TG. Regulation of specific protein synthesis in cytodifferentiation Journal of Cellular Physiology. 72: Suppl 1:1-18. PMID 5693298 DOI: 10.1002/JCP.1040720403  0.463
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