☰

Lei Cao, PhD - Publications

Affiliations: 
Molecular Virology, Immunology, and Molecular Genetics Ohio State University, Columbus, Columbus, OH 
Area:
Neuroscience, Cancer, Gene therapy, Virology, Metabolism
Website:
http://cancer.osu.edu/research/cancerresearch/researchprograms/biologygenetics/members/Pages/index.aspx?mid=3530
Tree Info Grants Similar researchers PubMed Report error

51 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Queen NJ, Huang W, Zou X, Mo X, Cao L. AAV-BDNF gene therapy ameliorates a hypothalamic neuroinflammatory signature in the -null model of Prader-Willi syndrome. Molecular Therapy. Methods & Clinical Development. 31: 101108. PMID 37766791 DOI: 10.1016/j.omtm.2023.09.004  0.811
2023 Anderson JM, Arnold WD, Huang W, Ray A, Owendoff G, Cao L. Long-term effects of a fat-directed FGF21 gene therapy in aged female mice. Gene Therapy. PMID 37699965 DOI: 10.1038/s41434-023-00422-0  0.341
2023 Appana B, Queen NJ, Cao L. Protocol to minimize the confounding effect of cold stress on socially isolated mice using thermoneutral housing. Star Protocols. 4: 102533. PMID 37660300 DOI: 10.1016/j.xpro.2023.102533  0.776
2023 Huang W, Bates R, Zou X, Queen NJ, Mo X, Arnold WD, Ray A, Owendoff G, Cao L. Environmental Enrichment Improves Motor Function and Muscle Transcriptome of Aged Mice. Advanced Biology. e2300148. PMID 37518850 DOI: 10.1002/adbi.202300148  0.787
2023 Queen NJ, Huang W, Komatineni S, Mansour AG, Xiao R, Chrislip LA, Cao L. Social isolation exacerbates diet-induced obesity and peripheral inflammation in young male mice under thermoneutrality. Iscience. 26: 106259. PMID 36915694 DOI: 10.1016/j.isci.2023.106259  0.791
2023 Anderson JM, Boardman AA, Bates R, Zou X, Huang W, Cao L. Hypothalamic TrkB.FL overexpression improves metabolic outcomes in the BTBR mouse model of autism. Plos One. 18: e0282566. PMID 36893171 DOI: 10.1371/journal.pone.0282566  0.354
2022 Queen NJ, Zou X, Anderson JM, Huang W, Appana B, Komatineni S, Wevrick R, Cao L. Hypothalamic AAV-BDNF gene therapy improves metabolic function and behavior in the -null mouse model of Prader-Willi syndrome. Molecular Therapy. Methods & Clinical Development. 27: 131-148. PMID 36284766 DOI: 10.1016/j.omtm.2022.09.012  0.809
2022 Xiao R, Mansour AG, Huang W, Hassan QN, Wilkins RK, Komatineni SV, Bates R, Ali S, Chrislip LA, Queen NJ, Ma S, Yu J, Lordo MR, Mundy-Bosse BL, Caligiuri MA, ... Cao L, et al. Adipocyte CD1d Gene Transfer Induces T Cell Expansion and Adipocyte Inflammation in CD1d Knockout Mice. Journal of Immunology (Baltimore, Md. : 1950). PMID 35418470 DOI: 10.4049/jimmunol.2100313  0.796
2021 Queen NJ, Deng H, Huang W, Mo X, Wilkins RK, Zhu T, Wu X, Cao L. Environmental enrichment mitigates age-related metabolic decline and Lewis lung carcinoma growth in aged female mice. Cancer Prevention Research (Philadelphia, Pa.). PMID 34535449 DOI: 10.1158/1940-6207.CAPR-21-0085  0.798
2021 Bergin SM, Xiao R, Huang W, Judd CRT, Liu X, Mansour AG, Queen N, Widstrom KJ, Caligiuri MA, Cao L. Environmental activation of a hypothalamic BDNF-adipocyte IL-15 axis regulates adipose- natural killer cells. Brain, Behavior, and Immunity. PMID 33989745 DOI: 10.1016/j.bbi.2021.05.005  0.789
2021 Cao L, Ali S, Queen NJ. Hypothalamic gene transfer of BDNF promotes healthy aging. Vitamins and Hormones. 115: 39-66. PMID 33706955 DOI: 10.1016/bs.vh.2020.12.003  0.828
2021 Queen NJ, Bates R, Huang W, Xiao R, Appana B, Cao L. Visceral adipose tissue-directed FGF21 gene therapy improves metabolic and immune health in BTBR mice. Molecular Therapy. Methods & Clinical Development. 20: 409-422. PMID 33575433 DOI: 10.1016/j.omtm.2020.12.011  0.804
2020 Huang W, Queen NJ, McMurphy TB, Ali S, Wilkins RK, Appana B, Cao L. Adipose PTEN acts as a downstream mediator of a brain-fat axis in environmental enrichment. Comprehensive Psychoneuroendocrinology. 4. PMID 35355831 DOI: 10.1016/j.cpnec.2020.100013  0.798
2020 Mansour AG, Xiao R, Bergin SM, Huang W, Chrislip LA, Zhang J, Ali S, Queen NJ, Caligiuri MA, Cao L. Enriched environment enhances NK cell maturation through hypothalamic BDNF in male mice. European Journal of Immunology. PMID 33169371 DOI: 10.1002/eji.201948358  0.79
2020 Hassan QN, Queen NJ, Cao L. Regulation of aging and cancer by enhanced environmental activation of a hypothalamic-sympathoneural-adipocyte axis. Translational Cancer Research. 9: 5687-5699. PMID 33134111 DOI: 10.21037/tcr.2020.02.39  0.783
2020 Queen NJ, Hassan QN, Cao L. Improvements to Healthspan Through Environmental Enrichment and Lifestyle Interventions: Where Are We Now? Frontiers in Neuroscience. 14: 605. PMID 32655354 DOI: 10.3389/fnins.2020.00605  0.776
2020 Ali S, Mansour AG, Huang W, Queen NJ, Mo X, Anderson JM, Hassan Ii QN, Patel RS, Wilkins RK, Caligiuri MA, Cao L. CSF1R inhibitor PLX5622 and environmental enrichment additively improve metabolic outcomes in middle-aged female mice. Aging. 12. PMID 32007953 DOI: 10.18632/aging.102724  0.812
2019 Huang W, Queen NJ, McMurphy TB, Ali S, Cao L. Adipose PTEN regulates adult adipose tissue homeostasis and redistribution via a PTEN-leptin-sympathetic loop. Molecular Metabolism. 30: 48-60. PMID 31767180 DOI: 10.1016/j.molmet.2019.09.008  0.776
2019 Queen NJ, Boardman AA, Patel RS, Siu JJ, Mo X, Cao L. Environmental enrichment improves metabolic and behavioral health in the BTBR mouse model of autism. Psychoneuroendocrinology. 111: 104476. PMID 31648110 DOI: 10.1016/j.psyneuen.2019.104476  0.789
2019 Zhao F, Siu JJ, Huang W, Askwith C, Cao L. Insulin Modulates Excitatory Synaptic Transmission and Synaptic Plasticity in the Mouse Hippocampus. Neuroscience. PMID 31146008 DOI: 10.1016/J.Neuroscience.2019.05.033  0.607
2019 Ali S, Liu X, Queen NJ, Patel RS, Wilkins RK, Mo X, Cao L. Long-term environmental enrichment affects microglial morphology in middle age mice. Aging. PMID 31039130 DOI: 10.18632/aging.101923  0.797
2019 Foglesong G, Queen N, Huang W, Widstrom K, Cao L. Enriched environment inhibits breast cancer progression in obese models with intact leptin signaling. Endocrine-Related Cancer. PMID 30856610 DOI: 10.1530/ERC-19-0075  0.786
2019 Xiao R, Mansour AG, Huang W, Chrislip LA, Wilkins RK, Queen NJ, Youssef Y, Mao HC, Caligiuri MA, Cao L. Adipocytes: A Novel Target for IL-15/IL-15Rα Cancer Gene Therapy. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 30833178 DOI: 10.1016/J.Ymthe.2019.02.011  0.768
2019 Huang W, Queen NJ, Cao L. rAAV-Mediated Gene Delivery to Adipose Tissue. Methods in Molecular Biology (Clifton, N.J.). 1950: 389-405. PMID 30783987 DOI: 10.1007/978-1-4939-9139-6_23  0.785
2018 McMurphy T, Huang W, Liu X, Siu JJ, Queen NJ, Xiao R, Cao L. Hypothalamic gene transfer of BDNF promotes healthy aging in mice. Aging Cell. e12846. PMID 30585393 DOI: 10.1111/acel.12846  0.813
2018 Xiao R, Bergin SM, Huang W, Mansour AG, Liu X, Judd RT, Widstrom KJ, Queen N, Wilkins R, Siu JJ, Ali S, Caligiuri MA, Cao L. Enriched environment regulates thymocyte development and alleviates experimental autoimmune encephalomyelitis in mice. Brain, Behavior, and Immunity. PMID 30287389 DOI: 10.1016/J.Bbi.2018.09.028  0.771
2018 McMurphy T, Huang W, Queen NJ, Ali S, Widstrom KJ, Liu X, Xiao R, Siu JJ, Cao L. Implementation of environmental enrichment after middle age promotes healthy aging. Aging. PMID 30036185 DOI: 10.18632/aging.101502  0.8
2017 Siu JJ, Queen NJ, Liu X, Huang W, McMurphy T, Cao L. Molecular Therapy of Melanocortin-4-Receptor Obesity by an Autoregulatory BDNF Vector. Molecular Therapy. Methods & Clinical Development. 7: 83-95. PMID 29296625 DOI: 10.1016/j.omtm.2017.09.005  0.798
2017 Huang W, Liu X, Queen NJ, Cao L. Targeting Visceral Fat by Intraperitoneal Delivery of Novel AAV Serotype Vector Restricting Off-Target Transduction in Liver. Molecular Therapy. Methods & Clinical Development. 6: 68-78. PMID 28702474 DOI: 10.1016/j.omtm.2017.06.002  0.793
2017 Zhang Y, Xie L, Gunasekar SK, Tong D, Mishra A, Gibson WJ, Wang C, Fidler T, Marthaler B, Klingelhutz A, Dale Abel E, Samuel I, Smith JK, Cao L, Sah R. SWELL1 is a regulator of adipocyte size, insulin signalling and glucose homeostasis. Nature Cell Biology. PMID 28436964 DOI: 10.1038/Ncb3514  0.337
2016 Foglesong GD, Huang W, Liu X, Slater AM, Siu J, Yildiz V, Salton SR, Cao L. Role of Hypothalamic VGF in Energy Balance and Metabolic Adaption to Environmental Enrichment in Mice. Endocrinology. en20151627. PMID 26730934 DOI: 10.1210/en.2015-1627  0.712
2015 During MJ, Liu X, Huang W, Magee D, Slater A, McMurphy T, Wang C, Cao L. Adipose VEGF Links the White-to-Brown Fat Switch With Environmental, Genetic, and Pharmacological Stimuli in Male Mice. Endocrinology. 156: 2059-73. PMID 25763639 DOI: 10.1210/en.2014-1905  0.546
2015 Samin A, Kurth M, Cao L. Ab initio study of radiation effects on the Li4Ti5O12 electrode used in lithium-ion batteries Aip Advances. 5: 47110. DOI: 10.1063/1.4917308  0.673
2015 Samin A, Cao L. Monte Carlo study of radiation-induced demagnetization using the two-dimensional Ising model Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions With Materials and Atoms. 360: 111-117. DOI: 10.1016/J.Nimb.2015.08.067  0.675
2014 Liu X, Magee D, Wang C, McMurphy T, Slater A, During M, Cao L. Adipose tissue insulin receptor knockdown via a new primate-derived hybrid recombinant AAV serotype. Molecular Therapy. Methods & Clinical Development. 1. PMID 25383359 DOI: 10.1038/mtm.2013.8  0.542
2014 Liu X, Mcmurphy T, Xiao R, Slater A, Huang W, Cao L. Hypothalamic gene transfer of BDNF inhibits breast cancer progression and metastasis in middle age obese mice Molecular Therapy. 22: 1275-1284. PMID 24637454 DOI: 10.1038/mt.2014.45  0.346
2014 Samin A, Qiu J, Hattrick-Simpers J, Dai-Hattrick L, Zheng YF, Cao L. Characterization of magnetic degradation mechanism in a high-neutron-flux environment Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions With Materials and Atoms. 334: 43-47. DOI: 10.1016/J.Nimb.2014.05.002  0.673
2013 Qiu J, Cao L, Mulligan P, Turkoglu D, Nagpure SC, Canova M, Co A. The potential of using Li-ion batteries for radiation detection Ieee Transactions On Nuclear Science. 60: 662-667. DOI: 10.1109/Tns.2012.2231097  0.612
2013 Turkoglu D, Cao L, Lewandowski R. A low-cost neutron radiography device Physics Procedia. 43: 54-65. DOI: 10.1016/J.Phpro.2013.03.007  0.603
2013 Yang T, Samin A, Cao L. A review of low-level ionizing radiation and risk models of leukemia Journal of Radiation Oncology. 2: 263-270. DOI: 10.1007/S13566-012-0086-Z  0.68
2012 Mulligan PL, Cao LR, Turkoglu D. A multi-detector, digitizer based neutron depth profiling device for characterizing thin film materials. The Review of Scientific Instruments. 83: 073303. PMID 22852681 DOI: 10.1063/1.4732168  0.57
2012 Cao L, During MJ. What is the brain-cancer connection? Annual Review of Neuroscience. 35: 331-45. PMID 22462541 DOI: 10.1146/annurev-neuro-062111-150546  0.498
2012 Lewandowski R, Cao L, Turkoglu D. Noise evaluation of a digital neutron imaging device Nuclear Instruments and Methods in Physics Research, Section a: Accelerators, Spectrometers, Detectors and Associated Equipment. 674: 46-50. DOI: 10.1016/J.Nima.2012.01.025  0.604
2011 Cao L, Choi EY, Liu X, Martin A, Wang C, Xu X, During MJ. White to brown fat phenotypic switch induced by genetic and environmental activation of a hypothalamic-adipocyte axis. Cell Metabolism. 14: 324-38. PMID 21907139 DOI: 10.1016/j.cmet.2011.06.020  0.578
2010 Cao L, Liu X, Lin EJ, Wang C, Choi EY, Riban V, Lin B, During MJ. Environmental and genetic activation of a brain-adipocyte BDNF/leptin axis causes cancer remission and inhibition. Cell. 142: 52-64. PMID 20603014 DOI: 10.1016/j.cell.2010.05.029  0.53
2009 Cao L, Lin EJ, Cahill MC, Wang C, Liu X, During MJ. Molecular therapy of obesity and diabetes by a physiological autoregulatory approach. Nature Medicine. 15: 447-54. PMID 19270710 DOI: 10.1038/nm.1933  0.551
2006 During MJ, Cao L. VEGF, a mediator of the effect of experience on hippocampal neurogenesis. Current Alzheimer Research. 3: 29-33. PMID 16472200 DOI: 10.2174/156720506775697133  0.47
2004 Cao L, Jiao X, Zuzga DS, Liu Y, Fong DM, Young D, During MJ. VEGF links hippocampal activity with neurogenesis, learning and memory. Nature Genetics. 36: 827-35. PMID 15258583 DOI: 10.1038/ng1395  0.456
2003 During MJ, Cao L, Zuzga DS, Francis JS, Fitzsimons HL, Jiao X, Bland RJ, Klugmann M, Banks WA, Drucker DJ, Haile CN. Glucagon-like peptide-1 receptor is involved in learning and neuroprotection. Nature Medicine. 9: 1173-9. PMID 12925848 DOI: 10.1038/Nm919  0.66
2002 Cao L, During M, Xiao W. Replication competent helper functions for recombinant AAV vector generation. Gene Therapy. 9: 1199-206. PMID 12215886 DOI: 10.1038/Sj.Gt.3301710  0.454
2000 Cao L, Liu Y, During MJ, Xiao W. High-titer, wild-type free recombinant adeno-associated virus vector production using intron-containing helper plasmids. Journal of Virology. 74: 11456-63. PMID 11090141 DOI: 10.1128/Jvi.74.24.11456-11463.2000  0.474
Show low-probability matches.