Year |
Citation |
Score |
2023 |
Bloom M, Oak N, Baskin-Doerfler R, Feng R, Iacobucci I, Baviskar P, Zhao X, Stroh AN, Li C, Ozark P, Tillman H, Li Y, Verbist KC, Albeituni S, Scott DC, ... ... Nichols KE, et al. ETV6 Represses Inflammatory Response Genes and Regulates HSPC Function During Stress Hematopoiesis in Mice. Blood Advances. PMID 37522715 DOI: 10.1182/bloodadvances.2022009313 |
0.328 |
|
2023 |
Shakoory B, Geerlinks A, Wilejto M, Kernan K, Hines M, Romano M, Piskin D, Ravelli A, Sinha R, Aletaha D, Allen C, Bassiri H, Behrens EM, Carcillo J, Carl L, ... ... Nichols KE, et al. The 2022 EULAR/ACR points to consider at the early stages of diagnosis and management of suspected haemophagocytic lymphohistiocytosis/macrophage activation syndrome (HLH/MAS). Annals of the Rheumatic Diseases. PMID 37487610 DOI: 10.1136/ard-2023-224123 |
0.572 |
|
2023 |
Shakoory B, Geerlinks A, Wilejto M, Kernan K, Hines M, Romano M, Piskin D, Ravelli A, Sinha R, Aletaha D, Allen C, Bassiri H, Behrens EM, Carcillo J, Carl L, ... ... Nichols KE, et al. The 2022 EULAR/ACR Points to Consider at the Early Stages of Diagnosis and Management of Suspected Haemophagocytic Lymphohistiocytosis/Macrophage Activation Syndrome (HLH/MAS). Arthritis & Rheumatology (Hoboken, N.J.). PMID 37486733 DOI: 10.1002/art.42636 |
0.57 |
|
2023 |
Steen EA, Nichols KE, Meyer LK. Insights into the cellular pathophysiology of familial hemophagocytic lymphohistiocytosis. Frontiers in Immunology. 14: 1147603. PMID 36969228 DOI: 10.3389/fimmu.2023.1147603 |
0.367 |
|
2021 |
Hines MR, Keenan C, Maron Alfaro G, Cheng C, Zhou Y, Sharma A, Hurley C, Nichols KE, Gottschalk S, Triplett BM, Talleur AC. Hemophagocytic lymphohistiocytosis-like toxicity (carHLH) after CD19-specific CAR T-cell therapy. British Journal of Haematology. PMID 34263927 DOI: 10.1111/bjh.17662 |
0.301 |
|
2021 |
Li Y, Yang W, Devidas M, Winter SS, Kesserwan C, Yang W, Dunsmore KP, Smith C, Qian M, Zhao X, Zhang R, Gastier-Foster JM, Raetz EA, Carroll WL, Li C, ... ... Nichols KE, et al. Germline RUNX1 variation and predisposition to childhood acute lymphoblastic leukemia. The Journal of Clinical Investigation. PMID 34166225 DOI: 10.1172/JCI147898 |
0.327 |
|
2021 |
Hines MR, Nichols KE. HLH or sepsis: the truth is in the T cells. Blood. 137: 2279-2280. PMID 33914076 DOI: 10.1182/blood.2020010236 |
0.341 |
|
2020 |
Guan P, Schaub R, Nichols KE, Das R. Combination of NKT14m and Low Dose IL-12 Promotes Invariant Natural Killer T Cell IFN-γ Production and Tumor Control. International Journal of Molecular Sciences. 21. PMID 32708464 DOI: 10.3390/Ijms21145085 |
0.383 |
|
2020 |
Patel NP, Guan P, Bahal D, Hashem T, Scheuplein F, Schaub R, Nichols KE, Das R. Cancer Immunotherapeutic Potential of NKTT320, a Novel, Invariant, Natural Killer T Cell-Activating, Humanized Monoclonal Antibody. International Journal of Molecular Sciences. 21. PMID 32560408 DOI: 10.3390/Ijms21124317 |
0.408 |
|
2020 |
Meyer L, Verbist KC, Albeituni S, Scull BP, Bassett R, Stroh AN, Tillman H, Allen CE, Hermiston M, Nichols KE. JAK/STAT pathway inhibition sensitizes CD8 T cells to dexamethasone-induced apoptosis in hyperinflammation. Blood. PMID 32530039 DOI: 10.1182/Blood.2020006075 |
0.363 |
|
2020 |
Lesmana H, Popescu M, Lewis S, Sahoo SS, Goodings-Harris C, Onciu M, Choi JK, Takemoto C, Nichols KE, Wlodarski M. Germline Gain-of-Function JAK3 Mutation in Familial Chronic Lymphoproliferative Disorder of NK Cells Blood. 136: 9-10. DOI: 10.1182/blood-2020-142078 |
0.363 |
|
2019 |
Bahal D, Hashem T, Nichols KE, Das R. SLAM-SAP-Fyn: Old Players with New Roles in iNKT Cell Development and Function. International Journal of Molecular Sciences. 20. PMID 31569599 DOI: 10.3390/Ijms20194797 |
0.411 |
|
2019 |
Albeituni S, Verbist KC, Tedrick PE, Tillman H, Picarsic J, Bassett R, Nichols KE. Mechanisms of action of ruxolitinib in murine models of hemophagocytic lymphohistiocytosis. Blood. 134: 147-159. PMID 31015190 DOI: 10.1182/blood.2019000761 |
0.323 |
|
2019 |
Das R, Guan P, Wiener SJ, Patel NP, Gohl TG, Evans E, Zauderer M, Nichols KE. Enhancing the antitumor functions of invariant natural killer T cells using a soluble CD1d-CD19 fusion protein. Blood Advances. 3: 813-824. PMID 30858151 DOI: 10.1182/Bloodadvances.2018028886 |
0.333 |
|
2019 |
Crayne CB, Albeituni S, Nichols KE, Cron RQ. The Immunology of Macrophage Activation Syndrome. Frontiers in Immunology. 10: 119. PMID 30774631 DOI: 10.3389/fimmu.2019.00119 |
0.336 |
|
2019 |
Crayne CB, Albeituni S, Nichols KE, Cron RQ. The Immunology of Macrophage Activation Syndrome. Frontiers in Immunology. 10: 119. PMID 30774631 DOI: 10.3389/fimmu.2019.00119 |
0.336 |
|
2019 |
Meyer LK, Verbist K, Albeituni S, Bassett R, Hermiston ML, Nichols KE. The Combination of Dexamethasone and Ruxolitinib Synergistically Attenuates Disease Manifestations in a Preclinical Model of Hemophagocytic Lymphohistiocytosis Blood. 134: 81-81. DOI: 10.1182/BLOOD-2019-129112 |
0.327 |
|
2018 |
Dillon SR, Lewis KE, Verbist K, Tedrick P, Albeituni S, Swanson R, Evans LS, Levin SD, Rixon MW, Peng SL, Nichols KE, Swiderek KM. Therapeutic Candidate Alpn-101, a Dual ICOS/CD28 Antagonist, Potently Suppresses Human/NSG Mouse Xenograft Graft Vs. Host Disease (GvHD) in a Dose Ranging Study and Reduces Disease Activity in a Mouse Model of Hemophagocytic Lymphohistiocytosis (HLH) Blood. 132: 2037-2037. DOI: 10.1182/BLOOD-2018-99-110001 |
0.353 |
|
2016 |
Guan P, Bassiri H, Patel NP, Nichols KE, Das R. Invariant natural killer T cells in hematopoietic stem cell transplantation: killer choice for natural suppression. Bone Marrow Transplantation. PMID 26878658 DOI: 10.1038/Bmt.2015.335 |
0.655 |
|
2016 |
Ruffo E, Malacarne V, Larsen SE, Das R, Patrussi L, Wülfing C, Biskup C, Kapnick SM, Verbist K, Tedrick P, Schwartzberg PL, Baldari CT, Rubio I, Nichols KE, Snow AL, et al. Inhibition of diacylglycerol kinase α restores restimulation-induced cell death and reduces immunopathology in XLP-1. Science Translational Medicine. 8: 321ra7. PMID 26764158 DOI: 10.1126/Scitranslmed.Aad1565 |
0.386 |
|
2016 |
Ruffo E, Malacarne V, Larsen SE, Das R, Patrussi L, Wülfing C, Biskup C, Kapnick SM, Verbist K, Tedrick P, Schwartzberg PL, Baldari CT, Rubio I, Nichols KE, Snow AL, et al. Inhibition of diacylglycerol kinase α restores restimulation-induced cell death and reduces immunopathology in XLP-1. Science Translational Medicine. 8: 321ra7. PMID 26764158 DOI: 10.1126/Scitranslmed.Aad1565 |
0.386 |
|
2016 |
Churchman ML, Qian M, Zhang R, Kronnie G, Yang W, Zhang H, Lana T, Tedrick P, Baskin R, Verbist K, Devidas M, Raetz E, Larsen E, Martin PL, Bowman WP, ... ... Nichols KE, et al. Germline Genetic Variation in IKZF1 and Predisposition to Childhood Acute Lymphoblastic Leukemia Blood. 128: LBA-2-LBA-2. DOI: 10.1182/blood.v128.22.lba-2.lba-2 |
0.333 |
|
2015 |
Das R, Scheuplein F, Guan P, Schaub R, Nichols KE. Abstract 4294: Cancer immunotherapeutic potential of NKTT320, a novel human invariant natural killer T-cell activating monoclonal antibody Cancer Research. 75: 4294-4294. DOI: 10.1158/1538-7445.Am2015-4294 |
0.405 |
|
2014 |
Bassiri H, Das R, Guan P, Barrett DM, Brennan PJ, Banerjee PP, Wiener SJ, Orange JS, Brenner MB, Grupp SA, Nichols KE. iNKT cell cytotoxic responses control T-lymphoma growth in vitro and in vivo . Cancer Immunology Research. 2: 59-69. PMID 24563871 DOI: 10.1158/2326-6066.Cir-13-0104 |
0.687 |
|
2014 |
Das R, Scheuplein F, Patel NP, Guan P, Schaub RG, Nichols KE. Abstract 653: NKTT320, a novel monoclonal antibody activates the immuno-stimulatory functions of human invariant natural killer T cells Cancer Research. 74: 653-653. DOI: 10.1158/1538-7445.Am2014-653 |
0.366 |
|
2014 |
Cianferoni A, Barni S, Smith C, Abraham V, Guan P, Saretta F, Ruyman K, Bassiri H, Nichols KE, Spergel JM. Older Mice Intranasally Sensitized with Aspergillus Fumigatus Develop Stronger Eosinophilic Esophageal Inflammation Compared to Their Younger Counterparts The Journal of Allergy and Clinical Immunology. 133. DOI: 10.1016/J.Jaci.2013.12.912 |
0.547 |
|
2013 |
Bassiri H, Das R, Nichols KE. Invariant NKT cells: Killers and conspirators against cancer. Oncoimmunology. 2: e27440. PMID 24575380 DOI: 10.4161/Onci.27440 |
0.677 |
|
2013 |
Teachey DT, Rheingold SR, Maude SL, Zugmaier G, Barrett DM, Seif AE, Nichols KE, Suppa EK, Kalos M, Berg RA, Fitzgerald JC, Aplenc R, Gore L, Grupp SA. Cytokine release syndrome after blinatumomab treatment related to abnormal macrophage activation and ameliorated with cytokine-directed therapy. Blood. 121: 5154-7. PMID 23678006 DOI: 10.1182/Blood-2013-02-485623 |
0.305 |
|
2013 |
Das R, Bassiri H, Guan P, Wiener S, Banerjee PP, Zhong MC, Veillette A, Orange JS, Nichols KE. The adaptor molecule SAP plays essential roles during invariant NKT cell cytotoxicity and lytic synapse formation. Blood. 121: 3386-95. PMID 23430111 DOI: 10.1182/Blood-2012-11-468868 |
0.686 |
|
2013 |
May RM, Okumura M, Hsu CJ, Bassiri H, Yang E, Rak G, Mace EM, Philip NH, Zhang W, Baumgart T, Orange JS, Nichols KE, Kambayashi T. Murine natural killer immunoreceptors use distinct proximal signaling complexes to direct cell function. Blood. 121: 3135-46. PMID 23407547 DOI: 10.1182/Blood-2012-12-474361 |
0.627 |
|
2012 |
Palendira U, Low C, Bell AI, Ma CS, Abbott RJ, Phan TG, Riminton DS, Choo S, Smart JM, Lougaris V, Giliani S, Buckley RH, Grimbacher B, Alvaro F, Klion AD, ... Nichols KE, et al. Expansion of somatically reverted memory CD8+ T cells in patients with X-linked lymphoproliferative disease caused by selective pressure from Epstein-Barr virus. The Journal of Experimental Medicine. 209: 913-24. PMID 22493517 DOI: 10.1084/jem.20112391 |
0.324 |
|
2012 |
Bassiri H, Nichols KE. X-linked lymphoproliferative disease (XLP) Atlas of Genetics and Cytogenetics in Oncology and Haematology. DOI: 10.4267/2042/47545 |
0.544 |
|
2011 |
Rezaei N, Mahmoudi E, Aghamohammadi A, Das R, Nichols KE. X-linked lymphoproliferative syndrome: a genetic condition typified by the triad of infection, immunodeficiency and lymphoma. British Journal of Haematology. 152: 13-30. PMID 21083659 DOI: 10.1111/J.1365-2141.2010.08442.X |
0.411 |
|
2010 |
Das R, Sant'Angelo DB, Nichols KE. Transcriptional control of invariant NKT cell development. Immunological Reviews. 238: 195-215. PMID 20969594 DOI: 10.1111/J.1600-065X.2010.00962.X |
0.416 |
|
2010 |
Kovalovsky D, Alonzo ES, Uche OU, Eidson M, Nichols KE, Sant'Angelo DB. PLZF induces the spontaneous acquisition of memory/effector functions in T cells independently of NKT cell-related signals. Journal of Immunology (Baltimore, Md. : 1950). 184: 6746-55. PMID 20495068 DOI: 10.4049/jimmunol.1000776 |
0.4 |
|
2010 |
Alonzo ES, Gottschalk RA, Das J, Egawa T, Hobbs RM, Pandolfi PP, Pereira P, Nichols KE, Koretzky GA, Jordan MS, Sant'Angelo DB. Development of promyelocytic zinc finger and ThPOK-expressing innate gamma delta T cells is controlled by strength of TCR signaling and Id3. Journal of Immunology (Baltimore, Md. : 1950). 184: 1268-79. PMID 20038637 DOI: 10.4049/Jimmunol.0903218 |
0.381 |
|
2010 |
Harly C, Guillaume Y, Mönkkönen H, Mönkkönen J, Olive D, Bonneville M, Scotet E, Morita CT, Fang Z, Wang H, Dornmair K, Bruder J, Siewert K, Hohlfeld R, Moens E, ... ... Nichols KE, et al. Gamma-delta T cells (WS-094) Chairpersons: Yoshimasa Tanaka, Marc Bonneville International Immunology. 22. DOI: 10.1093/Intimm/Dxq351 |
0.315 |
|
2009 |
Snow AL, Marsh RA, Krummey SM, Roehrs P, Young LR, Zhang K, van Hoff J, Dhar D, Nichols KE, Filipovich AH, Su HC, Bleesing JJ, Lenardo MJ. Restimulation-induced apoptosis of T cells is impaired in patients with X-linked lymphoproliferative disease caused by SAP deficiency. The Journal of Clinical Investigation. 119: 2976-89. PMID 19759517 DOI: 10.1172/JCI39518 |
0.404 |
|
2009 |
Talaat KR, Rothman JA, Cohen JI, Santi M, Choi JK, Guzman M, Zimmerman R, Nallasamy S, Brucker A, Quezado M, Pittaluga S, Patronas NJ, Klion AD, Nichols KE. Lymphocytic vasculitis involving the central nervous system occurs in patients with X-linked lymphoproliferative disease in the absence of Epstein-Barr virus infection. Pediatric Blood & Cancer. 53: 1120-3. PMID 19621458 DOI: 10.1002/Pbc.22185 |
0.307 |
|
2009 |
Bassiri H, Nichols KE. It's up to you Egr2. Immunology and Cell Biology. 87: 361-3. PMID 19333249 DOI: 10.1038/Icb.2009.20 |
0.66 |
|
2009 |
Cen O, Ueda A, Guzman L, Jain J, Bassiri H, Nichols KE, Stein PL. The adaptor molecule signaling lymphocytic activation molecule-associated protein (SAP) regulates IFN-gamma and IL-4 production in V alpha 14 transgenic NKT cells via effects on GATA-3 and T-bet expression. Journal of Immunology (Baltimore, Md. : 1950). 182: 1370-8. PMID 19155483 DOI: 10.4049/Jimmunol.182.3.1370 |
0.675 |
|
2009 |
Abraham V, Jyonouchi S, Nichols K, Spergel J, Orange J, Cianferoni A. Milk-Derived Glycoshingolipids (GSL) Specifically Ligate The Invariant NKT Cell (iNKT) T Cell Receptor (TCR), Induce iNKT Proliferation And Promote Th2 Cytokine Expression Journal of Allergy and Clinical Immunology. 123: 724. DOI: 10.1016/J.Jaci.2009.01.005 |
0.362 |
|
2008 |
Bassiri H, Janice Yeo WC, Rothman J, Koretzky GA, Nichols KE. X-linked lymphoproliferative disease (XLP): a model of impaired anti-viral, anti-tumor and humoral immune responses. Immunologic Research. 42: 145-59. PMID 18815745 DOI: 10.1007/S12026-008-8048-7 |
0.652 |
|
2008 |
Nunez-Cruz S, Yeo WC, Rothman J, Ojha P, Bassiri H, Juntilla M, Davidson D, Veillette A, Koretzky GA, Nichols KE. Differential requirement for the SAP-Fyn interaction during NK T cell development and function. Journal of Immunology (Baltimore, Md. : 1950). 181: 2311-20. PMID 18684920 DOI: 10.4049/Jimmunol.181.4.2311 |
0.672 |
|
2008 |
Baev DV, Caielli S, Ronchi F, Coccia M, Facciotti F, Nichols KE, Falcone M. Impaired SLAM-SLAM homotypic interaction between invariant NKT cells and dendritic cells affects differentiation of IL-4/IL-10-secreting NKT2 cells in nonobese diabetic mice. Journal of Immunology (Baltimore, Md. : 1950). 181: 869-77. PMID 18606638 DOI: 10.4049/jimmunol.181.2.869 |
0.332 |
|
2007 |
Ma CS, Nichols KE, Tangye SG. Regulation of cellular and humoral immune responses by the SLAM and SAP families of molecules. Annual Review of Immunology. 25: 337-79. PMID 17201683 DOI: 10.1146/annurev.immunol.25.022106.141651 |
0.372 |
|
2005 |
Ma CS, Hare NJ, Nichols KE, Dupré L, Andolfi G, Roncarolo MG, Adelstein S, Hodgkin PD, Tangye SG. Impaired humoral immunity in X-linked lymphoproliferative disease is associated with defective IL-10 production by CD4+ T cells. The Journal of Clinical Investigation. 115: 1049-59. PMID 15761493 DOI: 10.1172/JCI23139 |
0.353 |
|
2005 |
Nichols KE, Hom J, Gong SY, Ganguly A, Ma CS, Cannons JL, Tangye SG, Schwartzberg PL, Koretzky GA, Stein PL. Regulation of NKT cell development by SAP, the protein defective in XLP. Nature Medicine. 11: 340-5. PMID 15711562 DOI: 10.1038/Nm1189 |
0.453 |
|
2005 |
Nichols KE, Ma CS, Cannons JL, Schwartzberg PL, Tangye SG. Molecular and cellular pathogenesis of X-linked lymphoproliferative disease. Immunological Reviews. 203: 180-99. PMID 15661030 DOI: 10.1111/j.0105-2896.2005.00230.x |
0.319 |
|
2004 |
Cannons JL, Yu LJ, Hill B, Mijares LA, Dombroski D, Nichols KE, Antonellis A, Koretzky GA, Gardner K, Schwartzberg PL. SAP regulates T(H)2 differentiation and PKC-theta-mediated activation of NF-kappaB1. Immunity. 21: 693-706. PMID 15539155 DOI: 10.1016/J.Immuni.2004.09.012 |
0.366 |
|
2004 |
Nichols KE, Hom J, Ganguly A, Ma CS, Tangye SG, Cannons JL, Schwartzberg PL, Koretzky GA, Stein PL. Regulation of NKT Cell Development by Sap, the Adaptor Mutated in X-Linked Lymphoproliferative Disease. Blood. 104: 317-317. DOI: 10.1182/Blood.V104.11.317.317 |
0.434 |
|
2003 |
Zhong XP, Hainey EA, Olenchock BA, Jordan MS, Maltzman JS, Nichols KE, Shen H, Koretzky GA. Enhanced T cell responses due to diacylglycerol kinase zeta deficiency. Nature Immunology. 4: 882-90. PMID 12883552 DOI: 10.1038/Ni958 |
0.399 |
|
2003 |
Singer AL, Jordan MS, Judd BA, Myung PS, Newbrough SA, Nichols KE, Olenchock BA, Peterson EJ, Wu JN, Zhong X, Koretzky GA. Signaling Via the T Cell Receptor Science Signaling. 2003: cm7-cm7. DOI: 10.1126/Stke.2003.194.Cm7 |
0.303 |
|
2001 |
Nichols KE, Koretzky GA, June CH. SAP: Natural inhibitor or grand SLAM of T cell activation? Nature Immunology. 2: 665-666. PMID 11477397 DOI: 10.1038/90595 |
0.369 |
|
2000 |
Tangye SG, Phillips JH, Lanier LL, Nichols KE. Functional requirement for SAP in 2B4-mediated activation of human natural killer cells as revealed by the X-linked lymphoproliferative syndrome. Journal of Immunology (Baltimore, Md. : 1950). 165: 2932-6. PMID 10975798 DOI: 10.4049/Jimmunol.165.6.2932 |
0.339 |
|
1998 |
Nichols KE, Harkin DP, Levitz S, Krainer M, Kolquist KA, Genovese C, Bernard A, Ferguson M, Zuo L, Snyder E, Buckler AJ, Wise C, Ashley J, Lovett M, Valentine MB, et al. Inactivating mutations in an SH2 domain-encoding gene in X-linked lymphoproliferative syndrome. Proceedings of the National Academy of Sciences of the United States of America. 95: 13765-70. PMID 9811875 DOI: 10.1073/Pnas.95.23.13765 |
0.346 |
|
1986 |
Ball ED, Nichols KE, Pettengill OS, Sorenson GD, Fanger MW. Lysis of small cell carcinoma of the lung tumor cell lines by gamma interferon-activated allogeneic peripheral blood mononuclear cells: abrogation of killing by pretreatment of tumor cells with gamma interferon Cancer Immunology Immunotherapy. 22: 211-216. PMID 3015408 DOI: 10.1007/Bf00200035 |
0.324 |
|
Show low-probability matches. |