Peter J. Park - Publications

Affiliations: 
Department of Biomedical Informatics Harvard Medical School, Boston, MA, United States 

95 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Ganz J, Luquette LJ, Bizzotto S, Miller MB, Zhou Z, Bohrson CL, Jin H, Tran AV, Viswanadham VV, McDonough G, Brown K, Chahine Y, Chhouk B, Galor A, Park PJ, et al. Contrasting somatic mutation patterns in aging human neurons and oligodendrocytes. Cell. PMID 38503282 DOI: 10.1016/j.cell.2024.02.025  0.304
2023 Yang HW, Lee S, Berry BC, Yang D, Zheng S, Carroll RS, Park PJ, Johnson MD. A role for mutations in and other genes affecting ependymal cells in idiopathic normal pressure hydrocephalus. Proceedings of the National Academy of Sciences of the United States of America. 120: e2300681120. PMID 38100419 DOI: 10.1073/pnas.2300681120  0.605
2023 Kim SN, Viswanadham VV, Doan RN, Dou Y, Bizzotto S, Khoshkhoo S, Huang AY, Yeh R, Chhouk B, Truong A, Chappell KM, Beaudin M, Barton A, Akula SK, Rento L, ... ... Park PJ, et al. Cell lineage analysis with somatic mutations reveals late divergence of neuronal cell types and cortical areas in human cerebral cortex. Biorxiv : the Preprint Server For Biology. PMID 37986891 DOI: 10.1101/2023.11.06.565899  0.67
2023 Gao T, Kastriti ME, Ljungström V, Heinzel A, Tischler AS, Oberbauer R, Loh PR, Adameyko I, Park PJ, Kharchenko PV. A pan-tissue survey of mosaic chromosomal alterations in 948 individuals. Nature Genetics. 55: 1901-1911. PMID 37904053 DOI: 10.1038/s41588-023-01537-1  0.558
2023 Chu C, Lin EW, Tran A, Jin H, Ho NI, Veit A, Cortes-Ciriano I, Burns KH, Ting DT, Park PJ. The landscape of human SVA retrotransposons. Nucleic Acids Research. PMID 37823611 DOI: 10.1093/nar/gkad821  0.304
2023 Rodin RE, Dou Y, Kwon M, Sherman MA, D'Gama AM, Doan RN, Rento LM, Girskis KM, Bohrson CL, Kim SN, Nadig A, Luquette LJ, Gulhan DC, Park PJ, Walsh CA. Author Correction: The landscape of somatic mutation in cerebral cortex of autistic and neurotypical individuals revealed by ultra-deep whole-genome sequencing. Nature Neuroscience. PMID 37644260 DOI: 10.1038/s41593-023-01437-x  0.59
2023 Kim J, Woo S, de Gusmao CM, Zhao B, Chin DH, DiDonato RL, Nguyen MA, Nakayama T, Hu CA, Soucy A, Kuniholm A, Thornton JK, Riccardi O, Friedman DA, El Achkar CM, ... ... Park PJ, et al. A framework for individualized splice-switching oligonucleotide therapy. Nature. PMID 37438524 DOI: 10.1038/s41586-023-06277-0  0.646
2023 Rodriguez-Martin B, Alvarez EG, Baez-Ortega A, Zamora J, Supek F, Demeulemeester J, Santamarina M, Ju YS, Temes J, Garcia-Souto D, Detering H, Li Y, Rodriguez-Castro J, Dueso-Barroso A, Bruzos AL, ... ... Park PJ, et al. Author Correction: Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition. Nature Genetics. PMID 36944736 DOI: 10.1038/s41588-023-01319-9  0.454
2023 Cortés-Ciriano I, Lee JJ, Xi R, Jain D, Jung YL, Yang L, Gordenin D, Klimczak LJ, Zhang CZ, Pellman DS, Park PJ. Author Correction: Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing. Nature Genetics. PMID 36944733 DOI: 10.1038/s41588-023-01315-z  0.304
2022 Luquette LJ, Miller MB, Zhou Z, Bohrson CL, Zhao Y, Jin H, Gulhan D, Ganz J, Bizzotto S, Kirkham S, Hochepied T, Libert C, Galor A, Kim J, Lodato MA, ... ... Park PJ, et al. Single-cell genome sequencing of human neurons identifies somatic point mutation and indel enrichment in regulatory elements. Nature Genetics. PMID 36163278 DOI: 10.1038/s41588-022-01180-2  0.373
2022 Bae T, Fasching L, Wang Y, Shin JH, Suvakov M, Jang Y, Norton S, Dias C, Mariani J, Jourdon A, Wu F, Panda A, Pattni R, Chahine Y, Yeh R, ... ... Park PJ, et al. Analysis of somatic mutations in 131 human brains reveals aging-associated hypermutability. Science (New York, N.Y.). 377: 511-517. PMID 35901164 DOI: 10.1126/science.abm6222  0.701
2021 Cortés-Ciriano I, Gulhan DC, Lee JJ, Melloni GEM, Park PJ. Computational analysis of cancer genome sequencing data. Nature Reviews. Genetics. PMID 34880424 DOI: 10.1038/s41576-021-00431-y  0.344
2021 Borges-Monroy R, Chu C, Dias C, Choi J, Lee S, Gao Y, Shin T, Park PJ, Walsh CA, Lee EA. Whole-genome analysis reveals the contribution of non-coding de novo transposon insertions to autism spectrum disorder. Mobile Dna. 12: 28. PMID 34838103 DOI: 10.1186/s13100-021-00256-w  0.439
2021 Chu C, Borges-Monroy R, Viswanadham VV, Lee S, Li H, Lee EA, Park PJ. Comprehensive identification of transposable element insertions using multiple sequencing technologies. Nature Communications. 12: 3836. PMID 34158502 DOI: 10.1038/s41467-021-24041-8  0.501
2021 Wang Y, Bae T, Thorpe J, Sherman MA, Jones AG, Cho S, Daily K, Dou Y, Ganz J, Galor A, Lobon I, Pattni R, Rosenbluh C, Tomasi S, Tomasini L, ... ... Park PJ, et al. Comprehensive identification of somatic nucleotide variants in human brain tissue. Genome Biology. 22: 92. PMID 33781308 DOI: 10.1186/s13059-021-02285-3  0.686
2021 Rodin RE, Dou Y, Kwon M, Sherman MA, D'Gama AM, Doan RN, Rento LM, Girskis KM, Bohrson CL, Kim SN, Nadig A, Luquette LJ, Gulhan DC, Park PJ, et al. Author Correction: The landscape of somatic mutation in cerebral cortex of autistic and neurotypical individuals revealed by ultra-deep whole-genome sequencing. Nature Neuroscience. PMID 33753946 DOI: 10.1038/s41593-021-00830-8  0.698
2021 Bizzotto S, Dou Y, Ganz J, Doan RN, Kwon M, Bohrson CL, Kim SN, Bae T, Abyzov A, Park PJ, Walsh CA. Landmarks of human embryonic development inscribed in somatic mutations. Science (New York, N.Y.). 371: 1249-1253. PMID 33737485 DOI: 10.1126/science.abe1544  0.712
2021 Yang HW, Lee S, Yang D, Dai H, Zhang Y, Han L, Zhao S, Zhang S, Ma Y, Johnson MF, Rattray AK, Johnson TA, Wang G, Zheng S, Carroll RS, ... Park PJ, et al. Deletions in CWH43 cause idiopathic normal pressure hydrocephalus. Embo Molecular Medicine. e13249. PMID 33459505 DOI: 10.15252/emmm.202013249  0.589
2021 Rodin RE, Dou Y, Kwon M, Sherman MA, D'Gama AM, Doan RN, Rento LM, Girskis KM, Bohrson CL, Kim SN, Nadig A, Luquette LJ, Gulhan DC, Park PJ, et al. The landscape of somatic mutation in cerebral cortex of autistic and neurotypical individuals revealed by ultra-deep whole-genome sequencing. Nature Neuroscience. PMID 33432195 DOI: 10.1038/s41593-020-00765-6  0.695
2020 Jain D, Chu C, Alver BH, Lee S, Lee EA, Park PJ. HiTea: a computational pipeline to identify non-reference transposable element insertions in Hi-C data. Bioinformatics (Oxford, England). PMID 33136153 DOI: 10.1093/bioinformatics/btaa923  0.444
2020 Chu C, Zhao B, Park PJ, Lee EA. Identification and Genotyping of Transposable Element Insertions From Genome Sequencing Data. Current Protocols in Human Genetics. 107: e102. PMID 32662945 DOI: 10.1002/Cphg.102  0.682
2020 Huang AY, Li P, Rodin RE, Kim SN, Dou Y, Kenny CJ, Akula SK, Hodge RD, Bakken TE, Miller JA, Lein ES, Park PJ, Lee EA, Walsh CA. Parallel RNA and DNA analysis after deep sequencing (PRDD-seq) reveals cell type-specific lineage patterns in human brain. Proceedings of the National Academy of Sciences of the United States of America. PMID 32522880 DOI: 10.1073/Pnas.2006163117  0.77
2020 Cortés-Ciriano I, Lee JJ, Xi R, Jain D, Jung YL, Yang L, Gordenin D, Klimczak LJ, Zhang CZ, Pellman DS, Park PJ. Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing. Nature Genetics. PMID 32025003 DOI: 10.1038/S41588-019-0576-7  0.329
2020 Rodriguez-Martin B, Alvarez EG, Baez-Ortega A, Zamora J, Supek F, Demeulemeester J, Santamarina M, Ju YS, Temes J, Garcia-Souto D, Detering H, Li Y, Rodriguez-Castro J, Dueso-Barroso A, Bruzos AL, ... ... Park PJ, et al. Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition. Nature Genetics. PMID 32024998 DOI: 10.1038/S41588-019-0562-0  0.482
2020 Sieverling L, Hong C, Koser SD, Ginsbach P, Kleinheinz K, Hutter B, Braun DM, Cortés-Ciriano I, Xi R, Kabbe R, Park PJ, Eils R, Schlesner M, Brors B, et al. Genomic footprints of activated telomere maintenance mechanisms in cancer. Nature Communications. 11: 733. PMID 32024817 DOI: 10.1038/S41467-019-13824-9  0.307
2020 Dou Y, Kwon M, Rodin RE, Cortés-Ciriano I, Doan R, Luquette LJ, Galor A, Bohrson C, Walsh CA, Park PJ. Accurate detection of mosaic variants in sequencing data without matched controls. Nature Biotechnology. PMID 31907404 DOI: 10.1038/S41587-019-0368-8  0.708
2019 Zhang Y, Yang L, Kucherlapati M, Hadjipanayis A, Pantazi A, Bristow CA, Lee EA, Mahadeshwar HS, Tang J, Zhang J, Seth S, Lee S, Ren X, Song X, Sun H, ... ... Park PJ, et al. Global impact of somatic structural variation on the DNA methylome of human cancers. Genome Biology. 20: 209. PMID 31610796 DOI: 10.1186/S13059-019-1818-9  0.705
2019 Kim J, Hu C, Moufawad El Achkar C, Black LE, Douville J, Larson A, Pendergast MK, Goldkind SF, Lee EA, Kuniholm A, Soucy A, Vaze J, Belur NR, Fredriksen K, Stojkovska I, ... ... Park PJ, et al. Patient-Customized Oligonucleotide Therapy for a Rare Genetic Disease. The New England Journal of Medicine. PMID 31597037 DOI: 10.1056/Nejmoa1813279  0.377
2019 Luquette LJ, Bohrson CL, Sherman MA, Park PJ. Identification of somatic mutations in single cell DNA-seq using a spatial model of allelic imbalance. Nature Communications. 10: 3908. PMID 31467286 DOI: 10.1038/S41467-019-11857-8  0.301
2019 Yang L, Wang S, Lee JJ, Lee S, Lee E, Shinbrot E, Wheeler DA, Kucherlapati R, Park PJ. An enhanced genetic model of colorectal cancer progression history. Genome Biology. 20: 168. PMID 31416464 DOI: 10.1186/S13059-019-1782-4  0.689
2019 Bohrson CL, Barton AR, Lodato MA, Rodin RE, Luquette LJ, Viswanadham VV, Gulhan DC, Cortés-Ciriano I, Sherman MA, Kwon M, Coulter ME, Galor A, Walsh CA, Park PJ. Linked-read analysis identifies mutations in single-cell DNA-sequencing data. Nature Genetics. PMID 30886424 DOI: 10.1038/S41588-019-0366-2  0.324
2018 Zhang Y, Yang L, Kucherlapati M, Chen F, Hadjipanayis A, Pantazi A, Bristow CA, Lee EA, Mahadeshwar HS, Tang J, Zhang J, Seth S, Lee S, Ren X, Song X, ... ... Park PJ, et al. A Pan-Cancer Compendium of Genes Deregulated by Somatic Genomic Rearrangement across More Than 1,400 Cases. Cell Reports. 24: 515-527. PMID 29996110 DOI: 10.1016/J.Celrep.2018.06.025  0.7
2018 Fan J, Lee HO, Lee S, Ryu DE, Lee S, Xue C, Kim SJ, Kim K, Barkas N, Park PJ, Park WY, Kharchenko PV. Linking transcriptional and genetic tumor heterogeneity through allele analysis of single-cell RNA-seq data. Genome Research. PMID 29898899 DOI: 10.1101/Gr.228080.117  0.724
2018 Dou Y, Gold HD, Luquette LJ, Park PJ. Detecting Somatic Mutations in Normal Cells. Trends in Genetics : Tig. PMID 29731376 DOI: 10.1016/J.Tig.2018.04.003  0.695
2017 Cortes-Ciriano I, Lee S, Park WY, Kim TM, Park PJ. A molecular portrait of microsatellite instability across multiple cancers. Nature Communications. 8: 15180. PMID 28585546 DOI: 10.1038/Ncomms15180  0.345
2017 Zhang Y, Kwok-Shing Ng P, Kucherlapati M, Chen F, Liu Y, Tsang YH, de Velasco G, Jeong KJ, Akbani R, Hadjipanayis A, Pantazi A, Bristow CA, Lee E, Mahadeshwar HS, Tang J, ... ... Park PJ, et al. A Pan-Cancer Proteogenomic Atlas of PI3K/AKT/mTOR Pathway Alterations. Cancer Cell. PMID 28528867 DOI: 10.1016/J.Ccell.2017.04.013  0.686
2017 Lee S, Lee S, Ouellette S, Park WY, Lee EA, Park PJ. NGSCheckMate: software for validating sample identity in next-generation sequencing studies within and across data types. Nucleic Acids Research. PMID 28369524 DOI: 10.1093/Nar/Gkx193  0.462
2016 Saini N, Roberts SA, Klimczak LJ, Chan K, Grimm SA, Dai S, Fargo DC, Boyer JC, Kaufmann WK, Taylor JA, Lee E, Cortes-Ciriano I, Park PJ, Schurman SH, Malc EP, et al. The Impact of Environmental and Endogenous Damage on Somatic Mutation Load in Human Skin Fibroblasts. Plos Genetics. 12: e1006385. PMID 27788131 DOI: 10.1371/Journal.Pgen.1006385  0.373
2016 Xi R, Lee S, Xia Y, Kim TM, Park PJ. Copy number analysis of whole-genome data using BIC-seq2 and its application to detection of cancer susceptibility variants. Nucleic Acids Research. PMID 27260798 DOI: 10.1093/Nar/Gkw491  0.658
2016 Tica J, Lee E, Untergasser A, Meiers S, Garfield DA, Gokcumen O, Furlong EE, Park PJ, Stütz AM, Korbel JO. Next-generation sequencing-based detection of germline L1-mediated transductions. Bmc Genomics. 17: 342. PMID 27161561 DOI: 10.1186/S12864-016-2670-X  0.472
2016 Yang L, Lee MS, Lu H, Oh DY, Kim YJ, Park D, Park G, Ren X, Bristow CA, Haseley PS, Lee S, Pantazi A, Kucherlapati R, Park WY, Scott KL, ... ... Park PJ, et al. Analyzing Somatic Genome Rearrangements in Human Cancers by Using Whole-Exome Sequencing. American Journal of Human Genetics. 98: 843-856. PMID 27153396 DOI: 10.1016/J.Ajhg.2016.03.017  0.368
2016 Lee JK, Choi YL, Kwon M, Park PJ. Mechanisms and Consequences of Cancer Genome Instability: Lessons from Genome Sequencing Studies. Annual Review of Pathology. PMID 26907526 DOI: 10.1146/Annurev-Pathol-012615-044446  0.327
2016 Evrony GD, Lee E, Park PJ, Walsh CA. Resolving rates of mutation in the brain using single-neuron genomics. Elife. 5. PMID 26901440 DOI: 10.7554/Elife.12966  0.498
2016 Evrony GD, Lee E, Park PJ, Walsh CA. Author response: Resolving rates of mutation in the brain using single-neuron genomics Elife. DOI: 10.7554/Elife.12966.016  0.44
2015 De Los Angeles A, Ferrari F, Fujiwara Y, Mathieu R, Lee S, Lee S, Tu HC, Ross S, Chou S, Nguyen M, Wu Z, Theunissen TW, Powell BE, Imsoonthornruksa S, Chen J, ... ... Park PJ, et al. Corrigendum: Failure to replicate the STAP cell phenomenon. Nature. PMID 26675720 DOI: 10.1038/Nature16479  0.54
2015 Bersani F, Lee E, Kharchenko PV, Xu AW, Liu M, Xega K, MacKenzie OC, Brannigan BW, Wittner BS, Jung H, Ramaswamy S, Park PJ, Maheswaran S, Ting DT, Haber DA. Pericentromeric satellite repeat expansions through RNA-derived DNA intermediates in cancer. Proceedings of the National Academy of Sciences of the United States of America. PMID 26575630 DOI: 10.1073/Pnas.1518008112  0.671
2015 Jung H, Lee D, Lee J, Park D, Kim YJ, Park WY, Hong D, Park PJ, Lee E. Intron retention is a widespread mechanism of tumor-suppressor inactivation. Nature Genetics. PMID 26437032 DOI: 10.1038/Ng.3414  0.512
2015 Lodato MA, Woodworth MB, Lee S, Evrony GD, Mehta BK, Karger A, Lee S, Chittenden TW, D'Gama AM, Cai X, Luquette LJ, Lee E, Park PJ, Walsh CA. Somatic mutation in single human neurons tracks developmental and transcriptional history. Science (New York, N.Y.). 350: 94-8. PMID 26430121 DOI: 10.1126/Science.Aab1785  0.692
2015 De Los Angeles A, Ferrari F, Fujiwara Y, Mathieu R, Lee S, Lee S, Tu HC, Ross S, Chou S, Nguyen M, Wu Z, Theunissen TW, Powell BE, Imsoonthornruksa S, Chen J, ... ... Park PJ, et al. Failure to replicate the STAP cell phenomenon. Nature. 525: E6-9. PMID 26399835 DOI: 10.1038/Nature15513  0.54
2015 Nam JY, Kim NK, Kim SC, Joung JG, Xi R, Lee S, Park PJ, Park WY. Evaluation of somatic copy number estimation tools for whole-exome sequencing data. Briefings in Bioinformatics. PMID 26210357 DOI: 10.1093/Bib/Bbv055  0.638
2015 Brat DJ, Verhaak RG, Aldape KD, Yung WK, Salama SR, Cooper LA, Rheinbay E, Miller CR, Vitucci M, Morozova O, Robertson AG, Noushmehr H, Laird PW, Cherniack AD, ... ... Park PJ, et al. Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas. The New England Journal of Medicine. 372: 2481-98. PMID 26061751 DOI: 10.1056/Nejmoa1402121  0.557
2015 Evrony GD, Lee E, Mehta BK, Benjamini Y, Johnson RM, Cai X, Yang L, Haseley P, Lehmann HS, Park PJ, Walsh CA. Cell lineage analysis in human brain using endogenous retroelements. Neuron. 85: 49-59. PMID 25569347 DOI: 10.1016/J.Neuron.2014.12.028  0.469
2014 Kim TM, Park PJ. A genome-wide view of microsatellite instability: old stories of cancer mutations revisited with new sequencing technologies. Cancer Research. 74: 6377-82. PMID 25371413 DOI: 10.1158/0008-5472.Can-14-1225  0.361
2014 Parfenov M, Pedamallu CS, Gehlenborg N, Freeman SS, Danilova L, Bristow CA, Lee S, Hadjipanayis AG, Ivanova EV, Wilkerson MD, Protopopov A, Yang L, Seth S, Song X, Tang J, ... ... Park PJ, et al. Characterization of HPV and host genome interactions in primary head and neck cancers. Proceedings of the National Academy of Sciences of the United States of America. 111: 15544-9. PMID 25313082 DOI: 10.1073/Pnas.1416074111  0.608
2014 Ho JW, Jung YL, Liu T, Alver BH, Lee S, Ikegami K, Sohn KA, Minoda A, Tolstorukov MY, Appert A, Parker SC, Gu T, Kundaje A, Riddle NC, Bishop E, ... ... Park PJ, et al. Comparative analysis of metazoan chromatin organization. Nature. 512: 449-52. PMID 25164756 DOI: 10.1038/Nature13415  0.612
2014 Davis CF, Ricketts CJ, Wang M, Yang L, Cherniack AD, Shen H, Buhay C, Kang H, Kim SC, Fahey CC, Hacker KE, Bhanot G, Gordenin DA, Chu A, Gunaratne PH, ... ... Park PJ, et al. The somatic genomic landscape of chromophobe renal cell carcinoma. Cancer Cell. 26: 319-30. PMID 25155756 DOI: 10.1016/J.Ccr.2014.07.014  0.334
2014 Alekseyenko AA, Ho JWK, Peng S, Gelbart M, Tolstorukov MY, Plachetka A, Kharchenko PV, Jung YL, Gorchakov AA, Larschan E, Gu T, Minoda A, Riddle NC, Schwartz YB, Elgin SCR, ... ... Park PJ, et al. Correction: Sequence-Specific Targeting of Dosage Compensation in Drosophila Favors an Active Chromatin Context Plos Genetics. 10. DOI: 10.1371/annotation/39c76721-c8e1-4d42-ae6b-33063ce207d2  0.573
2013 Kim TM, Laird PW, Park PJ. The landscape of microsatellite instability in colorectal and endometrial cancer genomes. Cell. 155: 858-68. PMID 24209623 DOI: 10.1016/J.Cell.2013.10.015  0.38
2013 Ferrari F, Plachetka A, Alekseyenko AA, Jung YL, Ozsolak F, Kharchenko PV, Park PJ, Kuroda MI. "Jump start and gain" model for dosage compensation in Drosophila based on direct sequencing of nascent transcripts. Cell Reports. 5: 629-36. PMID 24183666 DOI: 10.1016/J.Celrep.2013.09.037  0.573
2013 Gokcumen O, Tischler V, Tica J, Zhu Q, Iskow RC, Lee E, Fritz MH, Langdon A, Stütz AM, Pavlidis P, Benes V, Mills RE, Park PJ, Lee C, Korbel JO. Primate genome architecture influences structural variation mechanisms and functional consequences. Proceedings of the National Academy of Sciences of the United States of America. 110: 15764-9. PMID 24014587 DOI: 10.1073/Pnas.1305904110  0.49
2013 Woo CJ, Kharchenko PV, Daheron L, Park PJ, Kingston RE. Variable requirements for DNA-binding proteins at polycomb-dependent repressive regions in human HOX clusters. Molecular and Cellular Biology. 33: 3274-85. PMID 23775117 DOI: 10.1128/Mcb.00275-13  0.57
2013 Apostolou E, Ferrari F, Walsh RM, Bar-Nur O, Stadtfeld M, Cheloufi S, Stuart HT, Polo JM, Ohsumi TK, Borowsky ML, Kharchenko PV, Park PJ, Hochedlinger K. Genome-wide chromatin interactions of the Nanog locus in pluripotency, differentiation, and reprogramming. Cell Stem Cell. 12: 699-712. PMID 23665121 DOI: 10.1016/J.Stem.2013.04.013  0.604
2013 Yang L, Luquette LJ, Gehlenborg N, Xi R, Haseley PS, Hsieh CH, Zhang C, Ren X, Protopopov A, Chin L, Kucherlapati R, Lee C, Park PJ. Diverse mechanisms of somatic structural variations in human cancer genomes. Cell. 153: 919-29. PMID 23663786 DOI: 10.1016/J.Cell.2013.04.010  0.36
2013 Ferrari F, Jung YL, Kharchenko PV, Plachetka A, Alekseyenko AA, Kuroda MI, Park PJ. Comment on "Drosophila dosage compensation involves enhanced Pol II recruitment to male X-linked promoters". Science (New York, N.Y.). 340: 273. PMID 23599463 DOI: 10.1126/Science.1231815  0.516
2013 Kim TM, Xi R, Luquette LJ, Park RW, Johnson MD, Park PJ. Functional genomic analysis of chromosomal aberrations in a compendium of 8000 cancer genomes. Genome Research. 23: 217-27. PMID 23132910 DOI: 10.1101/Gr.140301.112  0.326
2013 Woo CJ, Kharchenko PV, Daheron L, Park PJ, Kingston RE. Identification of regions in the HOX cluster that can confer repression in a Polycomb-dependent manner Epigenetics & Chromatin. 6. DOI: 10.1186/1756-8935-6-S1-P86  0.553
2012 Evrony GD, Cai X, Lee E, Hills LB, Elhosary PC, Lehmann HS, Parker JJ, Atabay KD, Gilmore EC, Poduri A, Park PJ, Walsh CA. Single-neuron sequencing analysis of L1 retrotransposition and somatic mutation in the human brain. Cell. 151: 483-96. PMID 23101622 DOI: 10.1016/J.Cell.2012.09.035  0.453
2012 Xi R, Lee S, Park PJ. A survey of copy-number variation detection tools based on high-throughput sequencing data. Current Protocols in Human Genetics / Editorial Board, Jonathan L. Haines ... [Et Al.]. Unit7.19. PMID 23074071 DOI: 10.1002/0471142905.Hg0719S75  0.627
2012 Riddle NC, Jung YL, Gu T, Alekseyenko AA, Asker D, Gui H, Kharchenko PV, Minoda A, Plachetka A, Schwartz YB, Tolstorukov MY, Kuroda MI, Pirrotta V, Karpen GH, Park PJ, et al. Enrichment of HP1a on Drosophila chromosome 4 genes creates an alternate chromatin structure critical for regulation in this heterochromatic domain. Plos Genetics. 8: e1002954. PMID 23028361 DOI: 10.1371/Journal.Pgen.1002954  0.608
2012 Landt SG, Marinov GK, Kundaje A, Kheradpour P, Pauli F, Batzoglou S, Bernstein BE, Bickel P, Brown JB, Cayting P, Chen Y, DeSalvo G, Epstein C, Fisher-Aylor KI, Euskirchen G, ... ... Park PJ, et al. ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia. Genome Research. 22: 1813-31. PMID 22955991 DOI: 10.1101/Gr.136184.111  0.576
2012 Schwartz YB, Linder-Basso D, Kharchenko PV, Tolstorukov MY, Kim M, Li HB, Gorchakov AA, Minoda A, Shanower G, Alekseyenko AA, Riddle NC, Jung YL, Gu T, Plachetka A, Elgin SC, ... ... Park PJ, et al. Nature and function of insulator protein binding sites in the Drosophila genome. Genome Research. 22: 2188-98. PMID 22767387 DOI: 10.1101/Gr.138156.112  0.601
2012 Lee E, Iskow R, Yang L, Gokcumen O, Haseley P, Luquette LJ, Lohr JG, Harris CC, Ding L, Wilson RK, Wheeler DA, Gibbs RA, Kucherlapati R, Lee C, Kharchenko PV, ... Park PJ, et al. Landscape of somatic retrotransposition in human cancers. Science (New York, N.Y.). 337: 967-71. PMID 22745252 DOI: 10.1126/Science.1222077  0.699
2012 Alekseyenko AA, Ho JW, Peng S, Gelbart M, Tolstorukov MY, Plachetka A, Kharchenko PV, Jung YL, Gorchakov AA, Larschan E, Gu T, Minoda A, Riddle NC, Schwartz YB, Elgin SC, ... ... Park PJ, et al. Sequence-specific targeting of dosage compensation in Drosophila favors an active chromatin context. Plos Genetics. 8: e1002646. PMID 22570616 DOI: 10.1371/Journal.Pgen.1002646  0.6
2012 Lee E, Iskow R, Yang L, Gokcumen O, Haseley P, Luquette LJ, Lohr JG, Harris CC, Ding L, Wilson RK, Wheeler DA, Gibbs RA, Kucherlapati R, Lee C, Kharchenko PV, ... Park PJ, et al. Analysis of somatic retrotransposition in human cancers Bmc Proceedings. 6. DOI: 10.1186/1753-6561-6-S6-O23  0.657
2011 Kharchenko PV, Xi R, Park PJ. Evidence for dosage compensation between the X chromosome and autosomes in mammals. Nature Genetics. 43: 1167-9; author reply. PMID 22120048 DOI: 10.1038/Ng.991  0.517
2011 Xi R, Hadjipanayis AG, Luquette LJ, Kim TM, Lee E, Zhang J, Johnson MD, Muzny DM, Wheeler DA, Gibbs RA, Kucherlapati R, Park PJ. Copy number variation detection in whole-genome sequencing data using the Bayesian information criterion. Proceedings of the National Academy of Sciences of the United States of America. 108: E1128-36. PMID 22065754 DOI: 10.1073/Pnas.1110574108  0.502
2011 Tolstorukov MY, Volfovsky N, Stephens RM, Park PJ. Impact of chromatin structure on sequence variability in the human genome. Nature Structural & Molecular Biology. 18: 510-5. PMID 21399641 DOI: 10.1038/Nsmb.2012  0.304
2011 Larschan E, Bishop EP, Kharchenko PV, Core LJ, Lis JT, Park PJ, Kuroda MI. X chromosome dosage compensation via enhanced transcriptional elongation in Drosophila. Nature. 471: 115-8. PMID 21368835 DOI: 10.1038/Nature09757  0.584
2011 Kharchenko PV, Alekseyenko AA, Schwartz YB, Minoda A, Riddle NC, Ernst J, Sabo PJ, Larschan E, Gorchakov AA, Gu T, Linder-Basso D, Plachetka A, Shanower G, Tolstorukov MY, Luquette LJ, ... ... Park PJ, et al. Comprehensive analysis of the chromatin landscape in Drosophila melanogaster. Nature. 471: 480-5. PMID 21179089 DOI: 10.1038/Nature09725  0.63
2011 Riddle NC, Minoda A, Kharchenko PV, Alekseyenko AA, Schwartz YB, Tolstorukov MY, Gorchakov AA, Jaffe JD, Kennedy C, Linder-Basso D, Peach SE, Shanower G, Zheng H, Kuroda MI, Pirrotta V, ... Park PJ, et al. Plasticity in patterns of histone modifications and chromosomal proteins in Drosophila heterochromatin. Genome Research. 21: 147-63. PMID 21177972 DOI: 10.1101/Gr.110098.110  0.611
2011 Egelhofer TA, Minoda A, Klugman S, Lee K, Kolasinska-Zwierz P, Alekseyenko AA, Cheung MS, Day DS, Gadel S, Gorchakov AA, Gu T, Kharchenko PV, Kuan S, Latorre I, Linder-Basso D, ... ... Park PJ, et al. An assessment of histone-modification antibody quality. Nature Structural & Molecular Biology. 18: 91-3. PMID 21131980 DOI: 10.1038/Nsmb.1972  0.504
2010 Tolstorukov MY, Kharchenko PV, Park PJ. Analysis of primary structure of chromatin with next-generation sequencing. Epigenomics. 2: 187-197. PMID 22022339 DOI: 10.2217/Epi.09.48  0.604
2010 Roy S, Ernst J, Kharchenko PV, Kheradpour P, Negre N, Eaton ML, Landolin JM, Bristow CA, Ma L, Lin MF, Washietl S, Arshinoff BI, Ay F, Meyer PE, ... ... Park PJ, et al. Identification of functional elements and regulatory circuits by Drosophila modENCODE. Science (New York, N.Y.). 330: 1787-97. PMID 21177974 DOI: 10.1126/Science.1198374  0.621
2010 Kim TM, Luquette LJ, Xi R, Park PJ. rSW-seq: algorithm for detection of copy number alterations in deep sequencing data. Bmc Bioinformatics. 11: 432. PMID 20718989 DOI: 10.1186/1471-2105-11-432  0.336
2010 Day DS, Luquette LJ, Park PJ, Kharchenko PV. Estimating enrichment of repetitive elements from high-throughput sequence data. Genome Biology. 11: R69. PMID 20584328 DOI: 10.1186/Gb-2010-11-6-R69  0.594
2010 Woo CJ, Kharchenko PV, Daheron L, Park PJ, Kingston RE. A region of the human HOXD cluster that confers polycomb-group responsiveness. Cell. 140: 99-110. PMID 20085705 DOI: 10.1016/J.Cell.2009.12.022  0.574
2010 Xi R, Luquette J, Hadjipanayis A, Kim T, Park PJ. BIC-seq: a fast algorithm for detection of copy number alterations based on high-throughput sequencing data Genome Biology. 11: 1-1. DOI: 10.1186/Gb-2010-11-S1-O10  0.315
2010 Gorchakov AA, Alekseyenko AA, Kharchenko PV, Park PJ, Kuroda MI. Dosage compensation in drosophila: Sequence-specific initiation and sequence-independent spreading of MSL complex to the active genes on the male X chromosome Russian Journal of Genetics. 46: 1263-1266. DOI: 10.1134/S1022795410100303  0.608
2009 Gorchakov AA, Alekseyenko AA, Kharchenko P, Park PJ, Kuroda MI. Long-range spreading of dosage compensation in Drosophila captures transcribed autosomal genes inserted on X. Genes & Development. 23: 2266-71. PMID 19797766 DOI: 10.1101/Gad.1840409  0.599
2009 Tolstorukov MY, Kharchenko PV, Goldman JA, Kingston RE, Park PJ. Comparative analysis of H2A.Z nucleosome organization in the human and yeast genomes. Genome Research. 19: 967-77. PMID 19246569 DOI: 10.1101/Gr.084830.108  0.604
2008 Kharchenko PV, Tolstorukov MY, Park PJ. Design and analysis of ChIP-seq experiments for DNA-binding proteins. Nature Biotechnology. 26: 1351-9. PMID 19029915 DOI: 10.1038/Nbt.1508  0.59
2008 Alekseyenko AA, Peng S, Larschan E, Gorchakov AA, Lee OK, Kharchenko P, McGrath SD, Wang CI, Mardis ER, Park PJ, Kuroda MI. A sequence motif within chromatin entry sites directs MSL establishment on the Drosophila X chromosome. Cell. 134: 599-609. PMID 18724933 DOI: 10.1016/J.Cell.2008.06.033  0.608
2008 Kharchenko PV, Woo CJ, Tolstorukov MY, Kingston RE, Park PJ. Nucleosome positioning in human HOX gene clusters. Genome Research. 18: 1554-61. PMID 18723689 DOI: 10.1101/Gr.075952.107  0.615
2008 Orford K, Kharchenko P, Lai W, Dao MC, Worhunsky DJ, Ferro A, Janzen V, Park PJ, Scadden DT. Differential H3K4 methylation identifies developmentally poised hematopoietic genes. Developmental Cell. 14: 798-809. PMID 18477461 DOI: 10.1016/J.Devcel.2008.04.002  0.587
2006 Liu F, Park PJ, Lai W, Maher E, Chakravarti A, Durso L, Jiang X, Yu Y, Brosius A, Thomas M, Chin L, Brennan C, DePinho RA, Kohane I, Carroll RS, et al. A genome-wide screen reveals functional gene clusters in the cancer genome and identifies EphA2 as a mitogen in glioblastoma. Cancer Research. 66: 10815-23. PMID 17090523 DOI: 10.1158/0008-5472.Can-06-1408  0.303
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