Tomas Luis Falzone - Publications

Affiliations: 
Universidad de Buenos Aires, Buenos Aires, Ciudad Autónoma de Buenos Aires, Argentina 
Area:
Neuroscience, Cell Biology.

36 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Facal CL, Fernández Bessone I, Muñiz JA, Pereyra AE, Pedroncini O, Páez-Paz I, Clerici-Delville R, Arnaiz C, Urrutia L, Falasco G, Argañaraz CV, Saez T, Marin-Burgin A, Soiza-Reilly M, Falzone T, et al. Tau reduction with artificial microRNAs modulates neuronal physiology and improves tauopathy phenotypes in mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 38310353 DOI: 10.1016/j.ymthe.2024.01.033  0.346
2022 Karmirian K, Holubiec M, Goto-Silva L, Fernandez Bessone I, Vitória G, Mello B, Alloatti M, Vanderborght B, Falzone TL, Rehen S. Modeling Alzheimer's Disease Using Human Brain Organoids. Methods in Molecular Biology (Clifton, N.J.). 2561: 135-158. PMID 36399268 DOI: 10.1007/978-1-0716-2655-9_7  0.767
2022 Fernandez Bessone I, Navarro J, Martinez E, Karmirian K, Holubiec M, Alloatti M, Goto-Silva L, Arnaiz Yepez C, Martins-de-Souza D, Nascimento JM, Bruno L, Saez TM, Rehen SK, Falzone TL. DYRK1A regulates the bidirectional axonal transport of APP in human-derived neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 35803734 DOI: 10.1523/JNEUROSCI.2551-21.2022  0.841
2020 Saez TM, Fernandez Bessone I, Rodriguez MS, Alloatti M, Otero MG, Cromberg LE, Pozo Devoto VM, Oubiña G, Sosa L, Buffone MG, Gelman DM, Falzone TL. Kinesin-1-mediated axonal transport of CB1 receptors is required for cannabinoid-dependent axonal growth and guidance. Development (Cambridge, England). PMID 32265198 DOI: 10.1242/Dev.184069  0.763
2019 Ferrero Restelli F, Fontanet PA, De Vincenti AP, Falzone TL, Ledda F, Paratcha G. Tetraspanin1 promotes NGF signaling by controlling TrkA receptor proteostasis. Cellular and Molecular Life Sciences : Cmls. PMID 31440771 DOI: 10.1007/S00018-019-03282-3  0.382
2019 Cromberg LE, Saez TMM, Otero MG, Tomasella E, Alloatti M, Damianich A, Devoto VP, Ferrario J, Gelman D, Rubinstein M, Falzone TL. Neuronal KIF5b deletion induces striatum-dependent locomotor impairments and defects in membrane presentation of dopamine D2 receptors. Journal of Neurochemistry. PMID 30664247 DOI: 10.1111/Jnc.14665  0.816
2018 Orqueda AJ, Gatti CR, Ogara MF, Falzone TL. SOX-11 regulates LINE-1 retrotransposon activity during neuronal differentiation. Febs Letters. PMID 30276805 DOI: 10.1002/1873-3468.13260  0.306
2018 Otero MG, Fernandez Bessone I, Hallberg AE, Cromberg LE, De Rossi MC, Saez TM, Levi V, Almenar-Queralt A, Falzone TL. Proteasome stress leads to APP axonal transport defects by promoting its amyloidogenic processing in lysosomes. Journal of Cell Science. 131. PMID 29724915 DOI: 10.1242/Jcs.214536  0.799
2018 Alloatti M, Bruno L, Falzone TL. Methods for Quantitative Analysis of Axonal Cargo Transport. Methods in Molecular Biology (Clifton, N.J.). 1727: 217-226. PMID 29222784 DOI: 10.1007/978-1-4939-7571-6_16  0.505
2018 Alloatti M, Bruno L, Falzone TL. Methods for Quantitative Analysis of Axonal Cargo Transport. Methods in Molecular Biology (Clifton, N.J.). 1727: 217-226. PMID 29222784 DOI: 10.1007/978-1-4939-7571-6_16  0.586
2017 Pozo Devoto VM, Falzone TL. Mitochondrial dynamics in Parkinson's disease: a role for α-synuclein? Disease Models & Mechanisms. 10: 1075-1087. PMID 28883016 DOI: 10.1242/Dmm.026294  0.792
2017 Pozo Devoto VM, Dimopoulos N, Alloatti M, Pardi MB, Saez TM, Otero MG, Cromberg LE, Marín-Burgin A, Scassa ME, Stokin GB, Schinder AF, Sevlever G, Falzone TL. αSynuclein control of mitochondrial homeostasis in human-derived neurons is disrupted by mutations associated with Parkinson's disease. Scientific Reports. 7: 5042. PMID 28698628 DOI: 10.1038/S41598-017-05334-9  0.745
2017 Lacovich V, Espindola SL, Alloatti M, Pozo Devoto V, Cromberg LE, Čarná ME, Forte G, Gallo JM, Bruno L, Stokin GB, Avale ME, Falzone TL. Tau Isoforms Imbalance Impairs the Axonal Transport of the Amyloid Precursor Protein in Human Neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 37: 58-69. PMID 28053030 DOI: 10.1523/JNEUROSCI.2305-16.2017  0.818
2017 Alloatti M, Bessone IF, Hallberg A, Otero MG, Saez T, Rehen S, Falzone T. [P2-137]: PROTEASOME ACTIVITY INVOLVED IN THE MODIFICATIONS OF APP METABOLISM AND THE INDUCTION OF ALZHEIMER PATHOLOGY Alzheimer's & Dementia. 13: P658-P658. DOI: 10.1016/J.Jalz.2017.06.787  0.768
2016 Lacovich V, Espindola SL, Alloatti M, Pozo Devoto V, Cromberg L, Čarná M, Forte G, Gallo JM, Bruno L, Stokin GB, Avale ME, Falzone TL. Tau isoforms imbalance impairs the axonal transport of the amyloid precursor protein in human neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 27837099 DOI: 10.1523/JNEUROSCI.2305-16.2016  0.841
2016 Medina CS, Biris O, Falzone TL, Zhang X, Zimmerman AJ, Bearer EL. Hippocampal to basal forebrain transport of Mn(2+) is impaired by deletion of KLC1, a subunit of the conventional kinesin microtubule-based motor. Neuroimage. PMID 27751944 DOI: 10.1016/J.Neuroimage.2016.09.035  0.499
2015 Lacovich V, Alloatti M, Avale ME, Espindola S, Falzone T, Čarna M, Krell-Roesch J, Forte G, Geda YE, Stokin GB. P4-013: Perturbation of 3R/4R tau ratio impairs app axonal transport in neurons derived from human embryonic stem cells (HESC) Alzheimer's & Dementia. 11: P770-P770. DOI: 10.1016/J.Jalz.2015.06.1717  0.728
2014 Almenar-Queralt A, Falzone TL, Shen Z, Lillo C, Killian RL, Arreola AS, Niederst ED, Ng KS, Kim SN, Briggs SP, Williams DS, Goldstein LS. UV irradiation accelerates amyloid precursor protein (APP) processing and disrupts APP axonal transport. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 3320-39. PMID 24573290 DOI: 10.1523/Jneurosci.1503-13.2014  0.834
2014 Otero MG, Alloatti M, Cromberg LE, Almenar-Queralt A, Encalada SE, Pozo Devoto VM, Bruno L, Goldstein LS, Falzone TL. Fast axonal transport of the proteasome complex depends on membrane interaction and molecular motor function. Journal of Cell Science. 127: 1537-49. PMID 24522182 DOI: 10.1242/Jcs.140780  0.805
2012 Falzone TL, Stokin GB. Imaging amyloid precursor protein in vivo: an axonal transport assay. Methods in Molecular Biology (Clifton, N.J.). 846: 295-303. PMID 22367820 DOI: 10.1007/978-1-61779-536-7_25  0.781
2012 Otero MG, Cromberg L, Falzone T. O3-04-05: Coordinated proteasome and lysosome retrograde axonal transport is regulated by kinesin-1 clustering at projection ends Alzheimer's & Dementia. 8: P435-P436. DOI: 10.1016/J.Jalz.2012.05.1162  0.81
2011 Otero MG, Cromberg L, Falzone T. P3-147: Axonal transport of the ubiquitin-proteasome system and it relevance for protein degradation Alzheimer's & Dementia. 7: S562-S564. DOI: 10.1016/J.Jalz.2011.05.1587  0.831
2010 Falzone TL, Gunawardena S, McCleary D, Reis GF, Goldstein LS. Kinesin-1 transport reductions enhance human tau hyperphosphorylation, aggregation and neurodegeneration in animal models of tauopathies. Human Molecular Genetics. 19: 4399-408. PMID 20817925 DOI: 10.1093/Hmg/Ddq363  0.848
2009 Falzone TL, Stokin GB, Lillo C, Rodrigues EM, Westerman EL, Williams DS, Goldstein LS. Axonal stress kinase activation and tau misbehavior induced by kinesin-1 transport defects. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 5758-67. PMID 19420244 DOI: 10.1523/Jneurosci.0780-09.2009  0.859
2008 Stokin GB, Almenar-Queralt A, Gunawardena S, Rodrigues EM, Falzone T, Kim J, Lillo C, Mount SL, Roberts EA, McGowan E, Williams DS, Goldstein LS. Amyloid precursor protein-induced axonopathies are independent of amyloid-beta peptides. Human Molecular Genetics. 17: 3474-86. PMID 18694898 DOI: 10.1093/Hmg/Ddn240  0.851
2007 Bearer EL, Falzone TL, Zhang X, Biris O, Rasin A, Jacobs RE. Role of neuronal activity and kinesin on tract tracing by manganese-enhanced MRI (MEMRI). Neuroimage. 37: S37-46. PMID 17600729 DOI: 10.1016/J.Neuroimage.2007.04.053  0.399
2005 Stokin GB, Lillo C, Falzone TL, Brusch RG, Rockenstein E, Mount SL, Raman R, Davies P, Masliah E, Williams DS, Goldstein LS. Axonopathy and transport deficits early in the pathogenesis of Alzheimer's disease. Science (New York, N.Y.). 307: 1282-8. PMID 15731448 DOI: 10.1126/Science.1105681  0.823
2004 Gan L, Falzone TL, Zhang K, Rubinstein M, Baldessarini RJ, Tarazi FI. Enhanced expression of dopamine D(1) and glutamate NMDA receptors in dopamine D(4) receptor knockout mice. Journal of Molecular Neuroscience : Mn. 22: 167-78. PMID 14997010 DOI: 10.1385/Jmn:22:3:167  0.447
2004 Avale ME, Falzone TL, Gelman DM, Low MJ, Grandy DK, Rubinstein M. The dopamine D4 receptor is essential for hyperactivity and impaired behavioral inhibition in a mouse model of attention deficit/hyperactivity disorder. Molecular Psychiatry. 9: 718-26. PMID 14699433 DOI: 10.1038/Sj.Mp.4001474  0.61
2002 Falzone TL, Gelman DM, Young JI, Grandy DK, Low MJ, Rubinstein M. Absence of dopamine D4 receptors results in enhanced reactivity to unconditioned, but not conditioned, fear. The European Journal of Neuroscience. 15: 158-64. PMID 11860516 DOI: 10.1046/J.0953-816X.2001.01842.X  0.608
2001 Rubinstein M, Cepeda C, Hurst RS, Flores-Hernandez J, Ariano MA, Falzone TL, Kozell LB, Meshul CK, Bunzow JR, Low MJ, Levine MS, Grandy DK. Dopamine D4 receptor-deficient mice display cortical hyperexcitability. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 3756-63. PMID 11356863 DOI: 10.1523/Jneurosci.21-11-03756.2001  0.641
2001 Rubinstein M, Cepeda C, Hurst RS, Flores-Hernandez J, Ariano MA, Falzone TL, Kozell LB, Meshul CK, Bunzow JR, Low MJ, Levine MS, Grandy DK. Dopamine D4Receptor-Deficient Mice Display Cortical Hyperexcitability The Journal of Neuroscience. 21: 3756-3763. DOI: 10.1523/JNEUROSCI.21-11-03756.2001  0.451
2000 Defagot MC, Falzone TL, Low MJ, Grandy DK, Rubinstein M, Antonelli MC. Quantitative analysis of the dopamine D4 receptor in the mouse brain. Journal of Neuroscience Research. 59: 202-8. PMID 10650878 DOI: 10.1002/(Sici)1097-4547(20000115)59:2<202::Aid-Jnr6>3.0.Co;2-5  0.594
1998 Young JI, Otero V, Cerdán MG, Falzone TL, Chan EC, Low MJ, Rubinstein M. Authentic cell-specific and developmentally regulated expression of pro-opiomelanocortin genomic fragments in hypothalamic and hindbrain neurons of transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 6631-40. PMID 9712635 DOI: 10.1523/Jneurosci.18-17-06631.1998  0.626
1998 Cerdán MG, Young JI, Zino E, Falzone TL, Otero V, Torres HN, Rubinstein M. Accurate spatial and temporal transgene expression driven by a 3.8-kilobase promoter of the bovine beta-casein gene in the lactating mouse mammary gland. Molecular Reproduction and Development. 49: 236-45. PMID 9491375 DOI: 10.1002/(Sici)1098-2795(199803)49:3<236::Aid-Mrd3>3.0.Co;2-P  0.453
1997 Rubinstein M, Phillips TJ, Bunzow JR, Falzone TL, Dziewczapolski G, Zhang G, Fang Y, Larson JL, McDougall JA, Chester JA, Saez C, Pugsley TA, Gershanik O, Low MJ, Grandy DK. Mice lacking dopamine D4 receptors are supersensitive to ethanol, cocaine, and methamphetamine. Cell. 90: 991-1001. PMID 9323127 DOI: 10.1016/S0092-8674(00)80365-7  0.721
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