Year |
Citation |
Score |
2020 |
Noviany N, Samadi A, Yuliyan N, Hadi S, Aziz M, Purwitasari N, Mohamad S, Ismail NN, Gable KP, Mahmud T. Structure Characterization and Biological Activity of 2-Arylbenzofurans from an Indonesian Plant, (L.) Pers. Phytochemistry Letters. 35: 211-215. PMID 32863985 DOI: 10.1016/J.Phytol.2019.12.008 |
0.349 |
|
2020 |
Noviany N, Samadi A, Carpenter EL, Abugrain ME, Hadi S, Purwitasari N, Indra G, Indra A, Mahmud T. Structural revision of sesbagrandiflorains A and B, and synthesis and biological evaluation of 6-methoxy-2-arylbenzofuran derivatives. Journal of Natural Medicines. PMID 32809097 DOI: 10.1007/S11418-020-01445-2 |
0.389 |
|
2020 |
Nofiani R, Weisberg AJ, Tsunoda T, Panjaitan RGP, Brilliantoro R, Chang JH, Philmus B, Mahmud T. Antibacterial Potential of Secondary Metabolites from Indonesian Marine Bacterial Symbionts. International Journal of Microbiology. 2020: 8898631. PMID 32676116 DOI: 10.1155/2020/8898631 |
0.306 |
|
2020 |
Li CJ, Chen PN, Li HJ, Mahmud T, Wu DL, Xu J, Lan WJ. Potential Antidiabetic Fumiquinazoline Alkaloids from the Marine-Derived Fungus F41-1. Journal of Natural Products. PMID 32130008 DOI: 10.1021/Acs.Jnatprod.9B01096 |
0.353 |
|
2019 |
Guo YW, Gong BQ, Yuan J, Li HJ, Mahmud T, Huang Y, Li JF, Yang DP, Lan WJ. l-Phenylalanine Alters the Privileged Secondary Metabolite Production in the Marine-Derived Fungus F1-1. Journal of Natural Products. PMID 31886665 DOI: 10.1021/Acs.Jnatprod.9B00710 |
0.332 |
|
2019 |
Osborn AR, Mahmud T. Interkingdom Genetic Mix-and-Match To Produce Novel Sunscreens. Acs Synthetic Biology. 8: 2464-2471. PMID 31689088 DOI: 10.1021/Acssynbio.9B00352 |
0.359 |
|
2019 |
Nofiani R, Philmus B, Nindita Y, Mahmud T. 3-Ketoacyl-ACP synthase (KAS) III homologues and their roles in natural product biosynthesis. Medchemcomm. 10: 1517-1530. PMID 31673313 DOI: 10.1039/C9Md00162J |
0.312 |
|
2019 |
Eida AA, Abugrain ME, Brumsted CJ, Mahmud T. Glycosylation of acyl carrier protein-bound polyketides during pactamycin biosynthesis. Nature Chemical Biology. 15: 795-802. PMID 31308531 DOI: 10.1038/S41589-019-0314-6 |
0.344 |
|
2019 |
Eida AA, Mahmud T. The secondary metabolite pactamycin with potential for pharmaceutical applications: biosynthesis and regulation. Applied Microbiology and Biotechnology. 103: 4337-4345. PMID 31025074 DOI: 10.1007/S00253-019-09831-X |
0.374 |
|
2019 |
Fu C, Xie F, Hoffmann J, Wang Q, Bauer A, Brönstrup M, Mahmud T, Müller R. Front Cover: Armeniaspirol Antibiotic Biosynthesis: Chlorination and Oxidative Dechlorination Steps Affording Spiro[4.4]non‐8‐ene (ChemBioChem 6/2019) Chembiochem. 20: 734-734. DOI: 10.1002/Cbic.201900106 |
0.395 |
|
2018 |
Fu C, Xie F, Hoffmann J, Wang Q, Bauer A, Brönstrup M, Mahmud T, Müller R. Armeniaspirol antibiotic biosynthesis: Chlorination and oxidative dechlorination steps affording spiro[4.4]non-8-ene formation. Chembiochem : a European Journal of Chemical Biology. PMID 30556942 DOI: 10.1002/Cbic.201800791 |
0.503 |
|
2018 |
Lu W, Alanzi AR, Abugrain ME, Ito T, Mahmud T. Global and pathway-specific transcriptional regulations of pactamycin biosynthesis in Streptomyces pactum. Applied Microbiology and Biotechnology. PMID 30276712 DOI: 10.1007/S00253-018-9375-9 |
0.56 |
|
2018 |
Brumsted CJ, Carpenter EL, Indra AK, Mahmud T. Asymmetric Synthesis and Biological Activities of Pactamycin-Inspired Aminocyclopentitols. Organic Letters. PMID 29319326 DOI: 10.1021/Acs.Orglett.7B03681 |
0.311 |
|
2017 |
Osborn AR, Kean KM, Alseud KM, Almabruk KH, Asamizu S, Lee JA, Karplus PA, Mahmud T. Evolution and Distribution of C7-Cyclitol Synthases in Prokaryotes and Eukaryotes. Acs Chemical Biology. PMID 28182402 DOI: 10.1021/Acschembio.7B00066 |
0.369 |
|
2017 |
Abugrain ME, Brumsted CJ, Osborn AR, Philmus B, Mahmud T. A Highly Promiscuous β-Ketoacyl-ACP Synthase (KAS) III-like Protein is Involved in Pactamycin Biosynthesis. Acs Chemical Biology. PMID 28060484 DOI: 10.1021/Acschembio.6B01043 |
0.306 |
|
2016 |
Almabruk KH, Chang JH, Mahmud T. Total Synthesis of (±)-Isoperbergins and Correction of the Chemical Structure of Perbergin. Journal of Natural Products. PMID 27588436 DOI: 10.1021/Acs.Jnatprod.6B00621 |
0.371 |
|
2016 |
Abugrain ME, Lu W, Li Y, Serrill JD, Brumsted CJ, Osborn AR, Alani A, Ishmael JE, Kelly JX, Mahmud T. Interrogating the Tailoring Steps of Pactamycin Biosynthesis and Accessing New Pactamycin Analogues. Chembiochem : a European Journal of Chemical Biology. PMID 27305101 DOI: 10.1002/Cbic.201600261 |
0.562 |
|
2016 |
Li CS, Ding Y, Yang BJ, Hoffman N, Yin HQ, Mahmud T, Turkson J, Cao S. Eremophilane sesquiterpenes from Hawaiian endophytic fungus Chaetoconis sp. FT087. Phytochemistry. PMID 26995148 DOI: 10.1016/J.Phytochem.2016.03.005 |
0.307 |
|
2016 |
Abugrain ME, Lu W, Li Y, Serrill JD, Brumsted CJ, Osborn AR, Alani A, Ishmael JE, Kelly JX, Mahmud T. Cover Picture: Interrogating the Tailoring Steps of Pactamycin Biosynthesis and Accessing New Pactamycin Analogues (ChemBioChem 17/2016) Chembiochem. 17: 1579. DOI: 10.1002/Cbic.201600434 |
0.498 |
|
2015 |
Sheng Y, Lam PW, Shahab S, Santosa DA, Proteau PJ, Zabriskie TM, Mahmud T. Identification of Elaiophylin Skeletal Variants from the Indonesian Streptomyces sp. ICBB 9297. Journal of Natural Products. PMID 26510047 DOI: 10.1021/Acs.Jnatprod.5B00752 |
0.357 |
|
2015 |
Medema MH, Kottmann R, Yilmaz P, Cummings M, Biggins JB, Blin K, de Bruijn I, Chooi YH, Claesen J, Coates RC, Cruz-Morales P, Duddela S, Düsterhus S, Edwards DJ, Fewer DP, ... ... Mahmud T, et al. Minimum Information about a Biosynthetic Gene cluster. Nature Chemical Biology. 11: 625-31. PMID 26284661 DOI: 10.1038/Nchembio.1890 |
0.743 |
|
2015 |
Abuelizz HA, Mahmud T. Distinct Substrate Specificity and Catalytic Activity of the Pseudoglycosyltransferase VldE. Chemistry & Biology. 22: 724-33. PMID 26051218 DOI: 10.1016/J.Chembiol.2015.04.021 |
0.324 |
|
2015 |
Osborn AR, Almabruk KH, Holzwarth G, Asamizu S, LaDu J, Kean KM, Karplus PA, Tanguay RL, Bakalinsky AT, Mahmud T. De novo synthesis of a sunscreen compound in vertebrates. Elife. 4. PMID 25965179 DOI: 10.7554/Elife.05919 |
0.333 |
|
2015 |
Sheng Y, Fotso S, Serrill JD, Shahab S, Santosa DA, Ishmael JE, Proteau PJ, Zabriskie TM, Mahmud T. Succinylated Apoptolidins from Amycolatopsis sp. ICBB 8242. Organic Letters. 17: 2526-9. PMID 25945812 DOI: 10.1021/Acs.Orglett.5B01055 |
0.318 |
|
2015 |
Guha G, Lu W, Li S, Liang X, Kulesz-Martin MF, Mahmud T, Indra AK, Ganguli-Indra G. Novel Pactamycin Analogs Induce p53 Dependent Cell-Cycle Arrest at S-Phase in Human Head and Neck Squamous Cell Carcinoma (HNSCC) Cells. Plos One. 10: e0125322. PMID 25938491 DOI: 10.1371/Journal.Pone.0125322 |
0.468 |
|
2014 |
Creason AL, Vandeputte OM, Savory EA, Davis EW, Putnam ML, Hu E, Swader-Hines D, Mol A, Baucher M, Prinsen E, Zdanowska M, Givan SA, El Jaziri M, Loper JE, Mahmud T, et al. Analysis of genome sequences from plant pathogenic Rhodococcus reveals genetic novelties in virulence loci. Plos One. 9: e101996. PMID 25010934 DOI: 10.1371/Journal.Pone.0101996 |
0.365 |
|
2014 |
Nigam A, Almabruk KH, Saxena A, Yang J, Mukherjee U, Kaur H, Kohli P, Kumari R, Singh P, Zakharov LN, Singh Y, Mahmud T, Lal R. Modification of rifamycin polyketide backbone leads to improved drug activity against rifampicin-resistant Mycobacterium tuberculosis. The Journal of Biological Chemistry. 289: 21142-52. PMID 24923585 DOI: 10.1074/Jbc.M114.572636 |
0.544 |
|
2014 |
Kean KM, Codding SJ, Asamizu S, Mahmud T, Karplus PA. Structure of a sedoheptulose 7-phosphate cyclase: ValA from streptomyces hygroscopicus Biochemistry. 53: 4250-4260. PMID 24832673 DOI: 10.1021/Bi5003508 |
0.311 |
|
2013 |
Asamizu S, Abugreen M, Mahmud T. Comparative Metabolomic Analysis of an Alternative Biosynthetic Pathway to Pseudosugars in Actinosynnema mirum DSM 43827 Chembiochem. 14: 1548-1551. PMID 23939727 DOI: 10.1002/Cbic.201300384 |
0.338 |
|
2013 |
Flatt PM, Wu X, Perry S, Mahmud T. Genetic insights into pyralomicin biosynthesis in Nonomuraea spiralis IMC A-0156 Journal of Natural Products. 76: 939-946. PMID 23607523 DOI: 10.1021/Np400159A |
0.54 |
|
2013 |
Almabruk KH, Lu W, Li Y, Abugreen M, Kelly JX, Mahmud T. Mutasynthesis of fluorinated pactamycin analogues and their antimalarial activity Organic Letters. 15: 1678-1681. PMID 23521145 DOI: 10.1021/ol4004614 |
0.515 |
|
2012 |
Cavalier MC, Yim YS, Asamizu S, Neau D, Almabruk KH, Mahmud T, Lee YH. Mechanistic Insights into Validoxylamine A 7'-Phosphate Synthesis by VldE Using the Structure of the Entire Product Complex Plos One. 7. PMID 23028689 DOI: 10.1371/Journal.Pone.0044934 |
0.306 |
|
2012 |
Asamizu S, Xie P, Brumsted CJ, Flatt PM, Mahmud T. Evolutionary divergence of sedoheptulose 7-phosphate cyclases leads to several distinct cyclic products Journal of the American Chemical Society. 134: 12219-12229. PMID 22741921 DOI: 10.1021/Ja3041866 |
0.357 |
|
2012 |
Xie P, Sheng Y, Ito T, Mahmud T. Transcriptional regulation and increased production of asukamycin in engineered Streptomyces nodosus subsp. asukaensis strains Applied Microbiology and Biotechnology. 96: 451-460. PMID 22555913 DOI: 10.1007/S00253-012-4084-2 |
0.361 |
|
2011 |
Asamizu S, Yang J, Almabruk KH, Mahmud T. Pseudoglycosyltransferase catalyzes nonglycosidic C-N coupling in validamycin a biosynthesis Journal of the American Chemical Society. 133: 12124-12135. PMID 21766819 DOI: 10.1021/Ja203574U |
0.329 |
|
2011 |
Lu W, Roongsawang N, Mahmud T. Biosynthetic studies and genetic engineering of pactamycin analogs with improved selectivity toward malarial parasites. Chemistry & Biology. 18: 425-31. PMID 21513878 DOI: 10.1016/J.Chembiol.2011.01.016 |
0.519 |
|
2011 |
Yang J, Xu H, Zhang Y, Bai L, Deng Z, Mahmud T. Nucleotidylation of unsaturated carbasugar in validamycin biosynthesis. Organic & Biomolecular Chemistry. 9: 438-49. PMID 20981366 DOI: 10.1039/C0Ob00475H |
0.413 |
|
2010 |
Wilson MC, Gulder TA, Mahmud T, Moore BS. Shared biosynthesis of the saliniketals and rifamycins in Salinispora arenicola is controlled by the sare1259-encoded cytochrome P450. Journal of the American Chemical Society. 132: 12757-65. PMID 20726561 DOI: 10.1021/Ja105891A |
0.554 |
|
2010 |
Fotso S, Santosa DA, Saraswati R, Yang J, Mahmud T, Zabriskie TM, Proteau PJ. Modified phenazines from an Indonesian Streptomyces sp. Journal of Natural Products. 73: 472-5. PMID 20092333 DOI: 10.1021/Np9005647 |
0.371 |
|
2009 |
Ito T, Roongsawang N, Shirasaka N, Lu W, Flatt PM, Kasanah N, Miranda C, Mahmud T. Deciphering pactamycin biosynthesis and engineered production of new pactamycin analogues. Chembiochem : a European Journal of Chemical Biology. 10: 2253-65. PMID 19670201 DOI: 10.1002/Cbic.200900339 |
0.581 |
|
2009 |
Xu H, Zhang Y, Yang J, Mahmud T, Bai L, Deng Z. Alternative epimerization in C(7)N-aminocyclitol biosynthesis is catalyzed by ValD, a large protein of the vicinal oxygen chelate superfamily. Chemistry & Biology. 16: 567-76. PMID 19477421 DOI: 10.1016/J.Chembiol.2009.04.006 |
0.32 |
|
2009 |
Fotso S, Zabriskie TM, Proteau PJ, Flatt PM, Santosa DA, Mahmud T. Limazepines A-F, pyrrolo[1,4]benzodiazepine Antibiotics from an Indonesian Micrococcus sp. Journal of Natural Products. 72: 690-5. PMID 19388705 DOI: 10.1021/Np800827W |
0.4 |
|
2009 |
Wu X, Flatt PM, Xu H, Mahmud T. Biosynthetic gene cluster of cetoniacytone A, an unusual aminocyclitol from the endosymbiotic Bacterium Actinomyces sp. Lu 9419. Chembiochem : a European Journal of Chemical Biology. 10: 304-14. PMID 19101977 DOI: 10.1002/Cbic.200800527 |
0.551 |
|
2009 |
Xu H, Yang J, Bai L, Deng Z, Mahmud T. Genetically engineered production of 1,1'-bis-valienamine and validienamycin in Streptomyces hygroscopicus and their conversion to valienamine. Applied Microbiology and Biotechnology. 81: 895-902. PMID 18820907 DOI: 10.1007/S00253-008-1711-Z |
0.373 |
|
2008 |
Fotso S, Mahmud T, Zabriskie TM, Santosa DA, Proteau PJ. Rearranged and unrearranged angucyclinones from Indonesian Streptomyces spp. The Journal of Antibiotics. 61: 449-56. PMID 18776657 DOI: 10.1038/Ja.2008.61 |
0.346 |
|
2008 |
Choi WS, Wu X, Choeng YH, Mahmud T, Jeong BC, Lee SH, Chang YK, Kim CJ, Hong SK. Genetic organization of the putative salbostatin biosynthetic gene cluster including the 2-epi-5-epi-valiolone synthase gene in Streptomyces albus ATCC 21838. Applied Microbiology and Biotechnology. 80: 637-45. PMID 18648803 DOI: 10.1007/S00253-008-1591-2 |
0.563 |
|
2008 |
Xu H, Minagawa K, Bai L, Deng Z, Mahmud T. Catalytic analysis of the validamycin glycosyltransferase (ValG) and enzymatic production of 4''-epi-validamycin A. Journal of Natural Products. 71: 1233-6. PMID 18563934 DOI: 10.1021/Np800185K |
0.326 |
|
2008 |
Fotso S, Mahmud T, Zabriskie TM, Santosa DA, Sulastri, Proteau PJ. Angucyclinones from an Indonesian Streptomyces sp. Journal of Natural Products. 71: 61-5. PMID 18081255 DOI: 10.1021/Np0704102 |
0.373 |
|
2007 |
Schneiker S, Perlova O, Kaiser O, Gerth K, Alici A, Altmeyer MO, Bartels D, Bekel T, Beyer S, Bode E, Bode HB, Bolten CJ, Choudhuri JV, Doss S, Elnakady YA, ... ... Mahmud T, et al. Complete genome sequence of the myxobacterium Sorangium cellulosum. Nature Biotechnology. 25: 1281-9. PMID 17965706 DOI: 10.1038/Nbt1354 |
0.415 |
|
2007 |
Bode HB, Meiser P, Klefisch T, Cortina NS, Krug D, Göhring A, Schwär G, Mahmud T, Elnakady YA, Müller R. Mutasynthesis-derived myxalamids and origin of the isobutyryl-CoA starter unit of myxalamid B. Chembiochem : a European Journal of Chemical Biology. 8: 2139-44. PMID 17955482 DOI: 10.1002/Cbic.200700401 |
0.485 |
|
2007 |
Mahmud T, Flatt PM, Wu X. Biosynthesis of unusual aminocyclitol-containing natural products. Journal of Natural Products. 70: 1384-91. PMID 17661520 DOI: 10.1021/Np070210Q |
0.506 |
|
2007 |
Minagawa K, Zhang Y, Ito T, Bai L, Deng Z, Mahmud T. ValC, a new type of C7-Cyclitol kinase involved in the biosynthesis of the antifungal agent validamycin A. Chembiochem : a European Journal of Chemical Biology. 8: 632-41. PMID 17335096 DOI: 10.1002/Cbic.200600528 |
0.381 |
|
2007 |
Wu X, Flatt PM, Schlörke O, Zeeck A, Dairi T, Mahmud T. A comparative analysis of the sugar phosphate cyclase superfamily involved in primary and secondary metabolism. Chembiochem : a European Journal of Chemical Biology. 8: 239-48. PMID 17195255 DOI: 10.1002/Cbic.200600446 |
0.571 |
|
2007 |
Mahmud T. Isotope tracer investigations of natural products biosynthesis: The discovery of novel metabolic pathways Journal of Labelled Compounds and Radiopharmaceuticals. 50: 1039-1051. DOI: 10.1002/Jlcr.1391 |
0.344 |
|
2006 |
Müller I, Weinig S, Steinmetz H, Kunze B, Veluthoor S, Mahmud T, Müller R. A unique mechanism for methyl ester formation via an amide intermediate found in myxobacteria. Chembiochem : a European Journal of Chemical Biology. 7: 1197-205. PMID 16807964 DOI: 10.1002/Cbic.200600057 |
0.475 |
|
2006 |
Bai L, Li L, Xu H, Minagawa K, Yu Y, Zhang Y, Zhou X, Floss HG, Mahmud T, Deng Z. Functional analysis of the validamycin biosynthetic gene cluster and engineered production of validoxylamine A. Chemistry & Biology. 13: 387-97. PMID 16632251 DOI: 10.1016/J.Chembiol.2006.02.002 |
0.651 |
|
2006 |
Wenzel SC, Meiser P, Binz TM, Mahmud T, Müller R. Nichtribosomale Peptidbiosynthese: Punktmutationen und Überspringen eines Moduls führen zu chemischer Diversität Angewandte Chemie. 118: 2354-2360. DOI: 10.1002/Ange.200503737 |
0.337 |
|
2005 |
Yu Y, Bai L, Minagawa K, Jian X, Li L, Li J, Chen S, Cao E, Mahmud T, Floss HG, Zhou X, Deng Z. Gene cluster responsible for validamycin biosynthesis in Streptomyces hygroscopicus subsp. jinggangensis 5008. Applied and Environmental Microbiology. 71: 5066-76. PMID 16151088 DOI: 10.1128/Aem.71.9.5066-5076.2005 |
0.663 |
|
2005 |
Xu J, Wan E, Kim CJ, Floss HG, Mahmud T. Identification of tailoring genes involved in the modification of the polyketide backbone of rifamycin B by Amycolatopsis mediterranei S699. Microbiology (Reading, England). 151: 2515-28. PMID 16079331 DOI: 10.1099/Mic.0.28138-0 |
0.654 |
|
2005 |
Dickschat JS, Bode HB, Mahmud T, Müller R, Schulz S. A novel type of geosmin biosynthesis in myxobacteria. The Journal of Organic Chemistry. 70: 5174-82. PMID 15960521 DOI: 10.1021/Jo050449G |
0.452 |
|
2005 |
Xiong Y, Wu X, Mahmud T. A homologue of the Mycobacterium tuberculosis PapA5 protein, rif-orf20, is an acetyltransferase involved in the biosynthesis of antitubercular drug rifamycin B by Amycolatopsis mediterranei S699. Chembiochem : a European Journal of Chemical Biology. 6: 834-7. PMID 15791687 DOI: 10.1002/Cbic.200400387 |
0.449 |
|
2005 |
Mahmud T, Wenzel SC, Wan E, Wen KW, Bode HB, Gaitatzis N, Müller R. A biosynthetic pathway to isovaleryl-CoA in myxobacteria: the involvement of the mevalonate pathway. Chembiochem : a European Journal of Chemical Biology. 6: 322-30. PMID 15619721 DOI: 10.1002/Cbic.200400261 |
0.479 |
|
2003 |
Weinig S, Mahmud T, Müller R. Markerless mutations in the myxothiazol biosynthetic gene cluster: a delicate megasynthetase with a superfluous nonribosomal peptide synthetase domain. Chemistry & Biology. 10: 953-60. PMID 14583261 DOI: 10.1016/J.Chembiol.2003.09.013 |
0.459 |
|
2003 |
Weinig S, Hecht HJ, Mahmud T, Müller R. Melithiazol biosynthesis: further insights into myxobacterial PKS/NRPS systems and evidence for a new subclass of methyl transferases. Chemistry & Biology. 10: 939-52. PMID 14583260 DOI: 10.1016/J.Chembiol.2003.09.012 |
0.439 |
|
2003 |
Xu J, Mahmud T, Floss HG. Isolation and characterization of 27-O-demethylrifamycin SV methyltransferase provides new insights into the post-PKS modification steps during the biosynthesis of the antitubercular drug rifamycin B by Amycolatopsis mediterranei S699. Archives of Biochemistry and Biophysics. 411: 277-88. PMID 12623077 DOI: 10.1016/S0003-9861(03)00004-3 |
0.651 |
|
2003 |
Pullen CB, Schmitz P, Hoffmann D, Meurer K, Boettcher T, von Bamberg D, Pereira AM, de Castro França S, Hauser M, Geertsema H, van Wyk A, Mahmud T, Floss HG, Leistner E. Occurrence and non-detectability of maytansinoids in individual plants of the genera Maytenus and Putterlickia. Phytochemistry. 62: 377-87. PMID 12620351 DOI: 10.1016/S0031-9422(02)00550-2 |
0.611 |
|
2002 |
Arakawa K, Müller R, Mahmud T, Yu TW, Floss HG. Characterization of the early stage aminoshikimate pathway in the formation of 3-amino-5-hydroxybenzoic acid: the RifN protein specifically converts kanosamine into kanosamine 6-phosphate. Journal of the American Chemical Society. 124: 10644-5. PMID 12207505 DOI: 10.1021/Ja0206339 |
0.684 |
|
2002 |
Mahmud T, Bode HB, Silakowski B, Kroppenstedt RM, Xu M, Nordhoff S, Höfle G, Müller R. A novel biosynthetic pathway providing precursors for fatty acid biosynthesis and secondary metabolite formation in myxobacteria. The Journal of Biological Chemistry. 277: 32768-74. PMID 12084727 DOI: 10.1074/Jbc.M205222200 |
0.435 |
|
2002 |
Moss SJ, Bai L, Toelzer S, Carroll BJ, Mahmud T, Yu TW, Floss HG. Identification of asm19 as an acyltransferase attaching the biologically essential ester side chain of ansamitocins using N-desmethyl-4,5-desepoxymaytansinol, not maytansinol, as its substrate. Journal of the American Chemical Society. 124: 6544-5. PMID 12047169 DOI: 10.1021/Ja020214B |
0.729 |
|
2002 |
Bowers SG, Mahmud T, Floss HG. Biosynthetic studies on the alpha-glucosidase inhibitor acarbose: the chemical synthesis of dTDP-4-amino-4,6-dideoxy-alpha-D-glucose. Carbohydrate Research. 337: 297-304. PMID 11841810 DOI: 10.1016/S0008-6215(01)00323-8 |
0.603 |
|
2001 |
Mahmud T, Lee S, Floss HG. The biosynthesis of acarbose and validamycin. Chemical Record (New York, N.Y.). 1: 300-10. PMID 11893070 DOI: 10.1002/Tcr.1015 |
0.592 |
|
2001 |
Mahmud T, Xu J, Choi YU. Synthesis of 5-epi-[6-(2)H(2)]valiolone and stereospecifically monodeuterated 5-epi-valiolones: exploring the steric course of 5-epi-valiolone dehydratase in validamycin A biosynthesis. The Journal of Organic Chemistry. 66: 5066-73. PMID 11463258 DOI: 10.1021/Jo0101003 |
0.34 |
|
2001 |
Dong H, Mahmud T, Tornus I, Lee S, Floss HG. Biosynthesis of the validamycins: identification of intermediates in the biosynthesis of validamycin A by Streptomyces hygroscopicus var. limoneus. Journal of the American Chemical Society. 123: 2733-42. PMID 11456959 DOI: 10.1021/Ja003643N |
0.633 |
|
1999 |
Stratmann A, Mahmud T, Lee S, Distler J, Floss HG, Piepersberg W. The AcbC protein from Actinoplanes species is a C7-cyclitol synthase related to 3-dehydroquinate synthases and is involved in the biosynthesis of the alpha-glucosidase inhibitor acarbose. The Journal of Biological Chemistry. 274: 10889-96. PMID 10196166 DOI: 10.1074/Jbc.274.16.10889 |
0.668 |
|
1999 |
Mahmud T, Tornus I, Egelkrout E, Wolf E, Uy C, Floss HG, Lee S. Biosynthetic studies on the α-glucosidase inhibitor acarbose in Actinoplanes sp.: 2-epi-5-epi-valiolone is the direct precursor of the valienamine moiety Journal of the American Chemical Society. 121: X. DOI: 10.1021/Ja991102W |
0.647 |
|
1998 |
Murakami N, Umezome T, Mahmud T, Sugimoto M, Kobayashi M, Wataya Y, Kim HS. Anti-malarial activities of acylated bruceolide derivatives. Bioorganic & Medicinal Chemistry Letters. 8: 459-62. PMID 9871598 DOI: 10.1016/S0960-894X(98)00045-6 |
0.561 |
|
1997 |
Kobayashi M, Mahmud T, Yoshioka N, Shibuya H, Kitagawa I. Indonesian medicinal plants. XXI. Inhibitors of Na+/H+ exchanger from the bark of Erythrina variegata and the roots of Maclura cochinchinensis Chemical and Pharmaceutical Bulletin. 45: 1615-1619. PMID 9353889 DOI: 10.1248/Cpb.45.1615 |
0.693 |
|
1997 |
Kobayashi M, Mahmud T, Umezome T, Wang W, Murakami N, Kitagawa I. The absolute stereostructures of the polyacetylenic constituents of Ginseng Radix Rubra Tetrahedron. 53: 15691-15700. DOI: 10.1016/S0040-4020(97)10026-6 |
0.654 |
|
1996 |
Kitagawa I, Mahmud T, Yokota K, Nakagawa S, Mayumi T, Kobayashi M, Shibuya H. Indonesian medicinal plants. XVII. Characterization of quassinoids from the stems of Quassia indica. Chemical & Pharmaceutical Bulletin. 44: 2009-14. PMID 8945767 DOI: 10.1248/Cpb.44.2009 |
0.698 |
|
1996 |
Kitagawa I, Wei H, Nagao S, Mahmud T, Hori K, Kobayashi M, Uji T, Shibuya H. Indonesian Medicinal Plants. XIV. Characterization of 3'-O-Caffeoylsweroside, a new secoiridoid glucoside, and kelampayosides A and B, two new phenolic apioglucosides, from the bark of Anthocephalus chinensis (Rubiaceae). Chemical & Pharmaceutical Bulletin. 44: 1162-7. PMID 8814946 DOI: 10.1248/Cpb.44.1162 |
0.693 |
|
1996 |
Kobayashi M, Mahmud T, Tajima H, Wang W, Aoki S, Nakagawa S, Mayumi T, Kitagawa I. Marine natural products. XXXVI. Biologically active polyacetylenes, adociacetylenes A, B, C, and D, from an Okinawan Marine sponge of Adocia sp. Chemical & Pharmaceutical Bulletin. 44: 720-4. PMID 8681403 DOI: 10.1248/Cpb.44.720 |
0.708 |
|
1996 |
Hirata K, Nakagami H, Takashina J, Mahmud T, Kobayashi M, In Y, Ishida T, Miyamoto K. Novel violet pigment, nostocine a, an extracellular metabolite from cyanobacterium Nostoc spongiaeforme Heterocycles. 43: 1513-1519. DOI: 10.3987/Com-96-7494 |
0.55 |
|
1996 |
Kobayashi M, Mahmud T, Yoshioka N, Hori K, Shibuya H, Kitagawa I. Indonesian medicinal plants. XVIII. Kompasinol A, a new stilbeno- phenylpropanoid from the bark of Koompassia malaccensis (Fabaceae) Chemical and Pharmaceutical Bulletin. 44: 2249-2253. DOI: 10.1248/Cpb.44.2249 |
0.604 |
|
1996 |
Kitagawa I, Simanjuntak P, Mahmud T, Kobayashi M, Fujii S, Uji T, Shibuya H. Indonesian medicinal plants. XIII. Chemical structures of caesaldekarins c, d, and e, three additional cassane-type furanoditerpenes from the roots of Caesalpinia major (Fabaceae). Several interesting reaction products of caesaldekarin a provided by N-bromosuccinimide treatment Chemical and Pharmaceutical Bulletin. 44: 1157-1161. DOI: 10.1248/Cpb.44.1157 |
0.626 |
|
1995 |
Kitagawa I, Mahmud T, Kobayashi M, Roemantyo, Shibuya H. Taxol and its related taxoids from the needles of Taxus sumatrana. Chemical & Pharmaceutical Bulletin. 43: 365-7. PMID 7728941 DOI: 10.1248/Cpb.43.365 |
0.68 |
|
1995 |
Kobayashi M, Mahmud T, Umezome T, Kitagawa I. The absolute stereostructure of panaxytriol, a biologically active diacetylenic acetogenin, from Ginseng Radix Rubra Chemical and Pharmaceutical Bulletin. 43: 1595-1597. DOI: 10.1248/Cpb.43.1595 |
0.496 |
|
1994 |
Kitagawa I, Simanjuntak P, Hori K, Nagami N, Mahmud T, Shibuya H, Kobayashi M. Indonesian medicinal plants. VII. Seven new clerodane-type diterpenoids, peronemins A2, A3, B1, B2, B3, C1, and D1, from the leaves of Peronema canescens (Verbenaceae). Chemical & Pharmaceutical Bulletin. 42: 1050-5. PMID 8069955 DOI: 10.1248/Cpb.42.1050 |
0.693 |
|
1994 |
Kitagawa I, Mahmud T, Simanjuntak P, Hori K, Uji T, Shibuya H. Indonesian medicinal plants. VIII. Chemical structures of three new triterpenoids, bruceajavanin A, dihydrobruceajavanin A, and bruceajavanin B, and a new alkaloidal glycoside, bruceacanthinoside, from the stems of Brucea javanica (Simaroubaceae). Chemical & Pharmaceutical Bulletin. 42: 1416-21. PMID 7923464 DOI: 10.1248/Cpb.42.1416 |
0.612 |
|
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