Paul J. Fletcher - Publications

Affiliations: 
2012- Centre for Addiction and Mental Health 

153 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Fletcher PJ, Li Z, Ji XD, Lê AD. Established sensitization of ethanol-induced locomotor activity is not reversed by psilocybin or the 5-HT receptor agonist TCB-2 in male DBA/2J mice. Pharmacology, Biochemistry, and Behavior. 173703. PMID 38154589 DOI: 10.1016/j.pbb.2023.173703  0.34
2023 Rahbarnia A, Li Z, Fletcher PJ. Effects of psilocybin, the 5-HT receptor agonist TCB-2, and the 5-HT receptor antagonist M100907 on visual attention in male mice in the continuous performance test. Psychopharmacology. PMID 37855864 DOI: 10.1007/s00213-023-06474-9  0.303
2023 Fletcher PJ, Rahbarnia A, Li Z, Ji X, Higgins GA, Funk D, Lê AD. Effects of 5-HT receptor stimulation in male mice on behaviour and Fos expression: Feeding, reward and impulsivity. Behavioural Brain Research. 447: 114438. PMID 37059187 DOI: 10.1016/j.bbr.2023.114438  0.39
2020 Tong J, Meyer JH, Boileau I, Ang LC, Fletcher PJ, Furukawa Y, Kish SJ. Serotonin transporter protein in autopsied brain of chronic users of cocaine. Psychopharmacology. PMID 32494974 DOI: 10.1007/S00213-020-05562-4  0.326
2020 Abela AR, Browne CJ, Sargin D, Prevot TD, Ji XD, Li Z, Lambe EK, Fletcher PJ. Median raphe serotonin neurons promote anxiety-like behavior via inputs to the dorsal hippocampus. Neuropharmacology. 107985. PMID 32035145 DOI: 10.1016/J.Neuropharm.2020.107985  0.779
2020 Fugariu V, Zack MH, Nobrega JN, Fletcher PJ, Zeeb FD. Effects of exposure to chronic uncertainty and a sensitizing regimen of amphetamine injections on locomotion, decision-making, and dopamine receptors in rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 31905371 DOI: 10.1038/S41386-020-0599-X  0.742
2020 Abela AR, Ji XD, Li Z, Lê AD, Fletcher PJ. Clozapine reliably increases the motivation for food: parsing the role of the 5-HT and H receptors. Psychopharmacology. PMID 31897573 DOI: 10.1007/S00213-019-05425-7  0.433
2019 Higgins GA, Fletcher PJ, Shanahan WR. Lorcaserin: a review of its preclinical and clinical pharmacology and therapeutic potential. Pharmacology & Therapeutics. 107417. PMID 31629010 DOI: 10.1016/J.Pharmthera.2019.107417  0.323
2019 Su P, Lai TKY, Lee FHF, Abela AR, Fletcher PJ, Liu F. Disruption of SynGAP-dopamine D1 receptor complexes alters actin and microtubule dynamics and impairs GABAergic interneuron migration. Science Signaling. 12. PMID 31387938 DOI: 10.1126/Scisignal.Aau9122  0.33
2018 Tabbara RI, Fletcher PJ. Nicotine enhances responding for conditioned reinforcement via α4β2 nicotinic acetylcholine receptors in the ventral tegmental area, but not the nucleus accumbens or the prefrontal cortex. Neuropharmacology. 148: 68-76. PMID 30550794 DOI: 10.1016/J.Neuropharm.2018.12.011  0.359
2018 Browne CJ, Abela AR, Chu D, Li Z, Ji X, Lambe EK, Fletcher PJ. Dorsal raphe serotonin neurons inhibit operant responding for reward via inputs to the ventral tegmental area but not the nucleus accumbens: evidence from studies combining optogenetic stimulation and serotonin reuptake inhibition. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30420603 DOI: 10.1038/S41386-018-0271-X  0.787
2018 Funk D, Tamadon S, Coen K, Fletcher PJ, Lê AD. Kappa opioid receptors mediate yohimbine-induced increases in impulsivity in the 5-choice serial reaction time task. Behavioural Brain Research. PMID 30414973 DOI: 10.1016/J.Bbr.2018.11.006  0.379
2018 Abela AR, Li Z, Lê AD, Fletcher PJ. Clozapine reduces nicotine self-administration, blunts reinstatement of nicotine-seeking but increases responding for food. Addiction Biology. PMID 29575323 DOI: 10.1111/Adb.12619  0.357
2018 Volle J, Bregman T, Scott B, Diwan M, Raymond R, Fletcher PJ, Nobrega JN, Hamani C. Deep brain stimulation and fluoxetine exert different long-term changes in the serotonergic system. Neuropharmacology. PMID 29505786 DOI: 10.1016/J.Neuropharm.2018.03.005  0.416
2018 Fletcher PJ, Li Z, Silenieks LB, MacMillan C, DeLannoy I, Higgins GA. Preclinical evidence for combining the 5-HTreceptor agonist lorcaserin and varenicline as a treatment for nicotine dependence. Addiction Biology. PMID 29498158 DOI: 10.1111/Adb.12602  0.361
2017 Hasbi A, Perreault ML, Shen MYF, Fan T, Nguyen T, Alijaniaram M, Banasikowski TJ, Grace AA, O'Dowd BF, Fletcher PJ, George SR. Activation of Dopamine D1-D2 Receptor Complex Attenuates Cocaine Reward and Reinstatement of Cocaine-Seeking through Inhibition of DARPP-32, ERK, and ΔFosB. Frontiers in Pharmacology. 8: 924. PMID 29354053 DOI: 10.3389/Fphar.2017.00924  0.367
2017 Bregman T, Nona C, Volle J, Diwan M, Raymond R, Fletcher PJ, Nobrega JN, Hamani C. Deep brain stimulation induces antidepressant-like effects in serotonin transporter knockout mice. Brain Stimulation. PMID 29174865 DOI: 10.1016/J.Brs.2017.11.008  0.385
2017 Higgins GA, Zeeb FD, Fletcher PJ. Role of impulsivity and reward in the anti-obesity actions of 5-HT2C receptor agonists. Journal of Psychopharmacology (Oxford, England). 269881117735797. PMID 29072522 DOI: 10.1177/0269881117735797  0.716
2017 Zeeb FD, Li Z, Fisher DC, Zack MH, Fletcher PJ. Uncertainty exposure causes behavioural sensitization and increases risky decision-making in male rats: toward modelling gambling disorder. Journal of Psychiatry & Neuroscience : Jpn. 42: 170003. PMID 28832319 DOI: 10.1503/Jpn.170003  0.712
2017 Browne CJ, Ji X, Higgins GA, Fletcher PJ, Harvey-Lewis C. Pharmacological Modulation of 5-HT2C Receptor Activity Produces Bidirectional Changes in Locomotor Activity, Responding for a Conditioned Reinforcer, and Mesolimbic DA Release in C57BL/6 Mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28720903 DOI: 10.1038/Npp.2017.124  0.755
2017 Higgins GA, Silenieks LB, Patrick A, De Lannoy IA, Fletcher PJ, Parker LA, MacLusky NJ, Sullivan LC, Chavera TA, Berg KA. Studies To Examine Potential Tolerability Differences between the 5-HT2C Receptor Selective Agonists Lorcaserin and CP-809101. Acs Chemical Neuroscience. PMID 28338324 DOI: 10.1021/Acschemneuro.6B00444  0.355
2017 Fletcher PJ, Li Z, Coen KM, Lê AD. Acquisition of nicotine self-administration in amphetamine and phencyclidine models of schizophrenia: A role for stress? Schizophrenia Research. PMID 28318841 DOI: 10.1016/J.Schres.2017.02.028  0.365
2017 Fletcher PJ, Zeeb FD, Browne CJ, Higgins GA, Soko AD. Effects of 5-HT1A, 5-HT2A and 5-HT2C receptor agonists and antagonists on responding for a conditioned reinforcer and its enhancement by methylphenidate. Psychopharmacology. PMID 28097374 DOI: 10.1007/S00213-017-4529-5  0.78
2016 Lister J, Andreazza AC, Navaid B, Wilson VS, Teo C, Nesarajah Y, Wilson AA, Nobrega JN, Fletcher PJ, Remington G. Lipoic Acid and Haloperidol-Induced Vacuous Chewing Movements: Implications for Prophylactic Antioxidant Use in Tardive Dyskinesia. Progress in Neuro-Psychopharmacology & Biological Psychiatry. PMID 27565433 DOI: 10.1016/J.Pnpbp.2016.08.010  0.31
2016 Perreault ML, Hasbi A, Shen MY, Fan T, Navarro G, Fletcher PJ, Franco R, Lanciego JL, George SR. Disruption of a dopamine receptor complex amplifies the actions of cocaine. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. PMID 27480020 DOI: 10.1016/J.Euroneuro.2016.07.008  0.375
2016 Higgins GA, Silenieks LB, Altherr EB, MacMillan C, Fletcher PJ, Pratt WE. Lorcaserin and CP-809101 reduce motor impulsivity and reinstatement of food seeking behavior in male rats: Implications for understanding the anti-obesity property of 5-HT2C receptor agonists. Psychopharmacology. PMID 27241709 DOI: 10.1007/S00213-016-4329-3  0.354
2016 Browne CJ, Fletcher PJ. Decreased Incentive Motivation Following Knockout or Acute Blockade of the Serotonin Transporter: Role of the 5-HT2C Receptor. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 27125304 DOI: 10.1038/Npp.2016.63  0.761
2016 McCormick PN, Fletcher PJ, Wilson VS, Remington GJ. The adrenergic α2 antagonist atipamezole alters the behavioural effects of pramipexole and increases pramipexole concentration in blood plasma. Life Sciences. 151: 300-4. PMID 26976325 DOI: 10.1016/J.Lfs.2016.03.017  0.378
2016 Zeeb FD, Soko AD, Ji X, Fletcher PJ. Low Impulsive Action, but not Impulsive Choice, Predicts Greater Conditioned Reinforcer Salience and Augmented Nucleus Accumbens Dopamine Release. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 26781518 DOI: 10.1038/Npp.2016.9  0.735
2015 Browne CJ, Fletcher PJ, Zeeb FD. Responding for a conditioned reinforcer or unconditioned sensory reinforcer in mice: interactions with environmental enrichment, social isolation, and monoamine reuptake inhibitors. Psychopharmacology. PMID 26690588 DOI: 10.1007/S00213-015-4178-5  0.739
2015 Harvey-Lewis C, Li Z, Higgins GA, Fletcher PJ. The 5-HT2C receptor agonist lorcaserin reduces cocaine self-administration, reinstatement of cocaine-seeking and cocaine induced locomotor activity. Neuropharmacology. PMID 26427596 DOI: 10.1016/J.Neuropharm.2015.09.028  0.367
2015 Higgins GA, Fletcher PJ. Therapeutic Potential of 5-HT2C Receptor Agonists for Addictive Disorders. Acs Chemical Neuroscience. 6: 1071-88. PMID 25870913 DOI: 10.1021/Acschemneuro.5B00025  0.472
2015 Zeeb FD, Higgins GA, Fletcher PJ. The Serotonin 2C Receptor Agonist Lorcaserin Attenuates Intracranial Self-Stimulation and Blocks the Reward-Enhancing Effects of Nicotine. Acs Chemical Neuroscience. 6: 1231-40. PMID 25781911 DOI: 10.1021/Acschemneuro.5B00017  0.764
2015 Higgins GA, Desnoyer J, Van Niekerk A, Silenieks LB, Lau W, Thevarkunnel S, Izhakova J, DeLannoy IA, Fletcher PJ, DeLay J, Dobson H. Characterization of the 5-HT2C receptor agonist lorcaserin on efficacy and safety measures in a rat model of diet-induced obesity. Pharmacology Research & Perspectives. 3: e00084. PMID 25692009 DOI: 10.1002/Prp2.84  0.358
2015 McCormick PN, Fletcher PJ, Wilson VS, Browne JD, Nobrega JN, Remington GJ. Low dose pramipexole causes D3 receptor-independent reduction of locomotion and responding for a conditioned reinforcer. Neuropharmacology. 89: 225-31. PMID 25283483 DOI: 10.1016/J.Neuropharm.2014.09.026  0.393
2014 Su P, Li S, Chen S, Lipina TV, Wang M, Lai TK, Lee FH, Zhang H, Zhai D, Ferguson SS, Nobrega JN, Wong AH, Roder JC, Fletcher PJ, Liu F. A dopamine D2 receptor-DISC1 protein complex may contribute to antipsychotic-like effects. Neuron. 84: 1302-16. PMID 25433637 DOI: 10.1016/J.Neuron.2014.11.007  0.358
2014 Guy EG, Fisher DC, Higgins GA, Fletcher PJ. Examination of the effects of varenicline, bupropion, lorcaserin, or naltrexone on responding for conditioned reinforcement in nicotine-exposed rats. Behavioural Pharmacology. 25: 775-83. PMID 25230208 DOI: 10.1097/Fbp.0000000000000092  0.349
2014 Guy EG, Fletcher PJ. Responding for a conditioned reinforcer, and its enhancement by nicotine, is blocked by dopamine receptor antagonists and a 5-HT(2C) receptor agonist but not by a 5-HT(2A) receptor antagonist. Pharmacology, Biochemistry, and Behavior. 125: 40-7. PMID 25158104 DOI: 10.1016/J.Pbb.2014.08.006  0.488
2014 Browne JD, Soko AD, Fletcher PJ. Responding for conditioned reinforcement in C57BL/6 and CD-1 mice, and Sprague-Dawley rats: Effects of methylphenidate and amphetamine. Psychopharmacology. 231: 4503-16. PMID 24804572 DOI: 10.1007/S00213-014-3602-6  0.343
2014 Zack M, Featherstone RE, Mathewson S, Fletcher PJ. Chronic exposure to a gambling-like schedule of reward predictive stimuli can promote sensitization to amphetamine in rats. Frontiers in Behavioral Neuroscience. 8: 36. PMID 24574987 DOI: 10.3389/Fnbeh.2014.00036  0.416
2014 Guy EG, Fletcher PJ. The effects of nicotine exposure during Pavlovian conditioning in rats on several measures of incentive motivation for a conditioned stimulus paired with water. Psychopharmacology. 231: 2261-71. PMID 24317443 DOI: 10.1007/S00213-013-3375-3  0.325
2013 Higgins GA, Sellers EM, Fletcher PJ. From obesity to substance abuse: therapeutic opportunities for 5-HT2C receptor agonists. Trends in Pharmacological Sciences. 34: 560-70. PMID 24041919 DOI: 10.1016/J.Tips.2013.08.001  0.388
2013 Aleksandrova LR, Creed MC, Fletcher PJ, Lobo DS, Hamani C, Nobrega JN. Deep brain stimulation of the subthalamic nucleus increases premature responding in a rat gambling task. Behavioural Brain Research. 245: 76-82. PMID 23434606 DOI: 10.1016/J.Bbr.2013.02.011  0.32
2013 Wheeler AL, Lerch JP, Chakravarty MM, Friedel M, Sled JG, Fletcher PJ, Josselyn SA, Frankland PW. Adolescent cocaine exposure causes enduring macroscale changes in mouse brain structure. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 1797-803a. PMID 23365219 DOI: 10.1523/Jneurosci.3830-12.2013  0.323
2013 Burton CL, Rizos Z, Diwan M, Nobrega JN, Fletcher PJ. Antagonizing 5-HTâ‚‚A receptors with M100907 and stimulating 5-HTâ‚‚C receptors with Ro60-0175 blocks cocaine-induced locomotion and zif268 mRNA expression in Sprague-Dawley rats. Behavioural Brain Research. 240: 171-81. PMID 23201361 DOI: 10.1016/J.Bbr.2012.11.030  0.461
2013 Fletcher PJ, Soko AD, Higgins GA. Impulsive action in the 5-choice serial reaction time test in 5-HTâ‚‚c receptor null mutant mice. Psychopharmacology. 226: 561-70. PMID 23192316 DOI: 10.1007/S00213-012-2929-0  0.433
2013 Higgins GA, Silenieks LB, Lau W, de Lannoy IA, Lee DK, Izhakova J, Coen K, Le AD, Fletcher PJ. Evaluation of chemically diverse 5-HTâ‚‚c receptor agonists on behaviours motivated by food and nicotine and on side effect profiles. Psychopharmacology. 226: 475-90. PMID 23184281 DOI: 10.1007/S00213-012-2919-2  0.386
2013 Guy EG, Fletcher PJ. Nicotine-induced enhancement of responding for conditioned reinforcement in rats: role of prior nicotine exposure and α4β2 nicotinic receptors. Psychopharmacology. 225: 429-40. PMID 22885874 DOI: 10.1007/S00213-012-2832-8  0.333
2012 Tuerke KJ, Limebeer CL, Fletcher PJ, Parker LA. Double dissociation between regulation of conditioned disgust and taste avoidance by serotonin availability at the 5-HT(3) receptor in the posterior and anterior insular cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 13709-17. PMID 23035083 DOI: 10.1523/Jneurosci.2042-12.2012  0.425
2012 Creed MC, Hamani C, Bridgman A, Fletcher PJ, Nobrega JN. Contribution of decreased serotonin release to the antidyskinetic effects of deep brain stimulation in a rodent model of tardive dyskinesia: comparison of the subthalamic and entopeduncular nuclei. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 9574-81. PMID 22787043 DOI: 10.1523/Jneurosci.1196-12.2012  0.43
2012 Fletcher PJ, Rizos Z, Noble K, Soko AD, Silenieks LB, Lê AD, Higgins GA. Effects of the 5-HT2C receptor agonist Ro60-0175 and the 5-HT2A receptor antagonist M100907 on nicotine self-administration and reinstatement. Neuropharmacology. 62: 2288-98. PMID 22342986 DOI: 10.1016/J.Neuropharm.2012.01.023  0.451
2012 Burton CL, Fletcher PJ. Age and sex differences in impulsive action in rats: the role of dopamine and glutamate. Behavioural Brain Research. 230: 21-33. PMID 22326372 DOI: 10.1016/J.Bbr.2012.01.046  0.378
2012 Higgins GA, Silenieks LB, Rossmann A, Rizos Z, Noble K, Soko AD, Fletcher PJ. The 5-HT2C receptor agonist lorcaserin reduces nicotine self-administration, discrimination, and reinstatement: relationship to feeding behavior and impulse control. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 1177-91. PMID 22189292 DOI: 10.1038/Npp.2011.303  0.425
2012 Rock EM, Bolognini D, Limebeer CL, Cascio MG, Anavi-Goffer S, Fletcher PJ, Mechoulam R, Pertwee RG, Parker LA. Cannabidiol, a non-psychotropic component of cannabis, attenuates vomiting and nausea-like behaviour via indirect agonism of 5-HT(1A) somatodendritic autoreceptors in the dorsal raphe nucleus. British Journal of Pharmacology. 165: 2620-34. PMID 21827451 DOI: 10.1111/J.1476-5381.2011.01621.X  0.365
2011 Hahn M, Chintoh A, Giacca A, Xu L, Lam L, Mann S, Fletcher P, Guenette M, Cohn T, Wolever T, Arenovich T, Remington G. Atypical antipsychotics and effects of muscarinic, serotonergic, dopaminergic and histaminergic receptor binding on insulin secretion in vivo: an animal model. Schizophrenia Research. 131: 90-5. PMID 21696923 DOI: 10.1097/01.Yic.0000405882.94837.86  0.362
2011 Lovic V, Keen D, Fletcher PJ, Fleming AS. Early-life maternal separation and social isolation produce an increase in impulsive action but not impulsive choice. Behavioral Neuroscience. 125: 481-91. PMID 21688886 DOI: 10.1037/A0024367  0.312
2011 Burton CL, Noble K, Fletcher PJ. Enhanced incentive motivation for sucrose-paired cues in adolescent rats: possible roles for dopamine and opioid systems. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 1631-43. PMID 21508935 DOI: 10.1038/Npp.2011.44  0.372
2011 Fletcher PJ, Rizos Z, Noble K, Higgins GA. Impulsive action induced by amphetamine, cocaine and MK801 is reduced by 5-HT(2C) receptor stimulation and 5-HT(2A) receptor blockade. Neuropharmacology. 61: 468-77. PMID 21402085 DOI: 10.1016/J.Neuropharm.2011.02.025  0.474
2010 Pei L, Li S, Wang M, Diwan M, Anisman H, Fletcher PJ, Nobrega JN, Liu F. Uncoupling the dopamine D1-D2 receptor complex exerts antidepressant-like effects. Nature Medicine. 16: 1393-5. PMID 21113156 DOI: 10.1038/Nm.2263  0.35
2010 Perreault ML, Hasbi A, Alijaniaram M, Fan T, Varghese G, Fletcher PJ, Seeman P, O'Dowd BF, George SR. The dopamine D1-D2 receptor heteromer localizes in dynorphin/enkephalin neurons: increased high affinity state following amphetamine and in schizophrenia. The Journal of Biological Chemistry. 285: 36625-34. PMID 20864528 DOI: 10.1074/Jbc.M110.159954  0.375
2010 Wang M, Pei L, Fletcher PJ, Kapur S, Seeman P, Liu F. Schizophrenia, amphetamine-induced sensitized state and acute amphetamine exposure all show a common alteration: increased dopamine D2 receptor dimerization. Molecular Brain. 3: 25. PMID 20813060 DOI: 10.1186/1756-6606-3-25  0.402
2010 Fletcher PJ, Sinyard J, Higgins GA. Genetic and pharmacological evidence that 5-HT2C receptor activation, but not inhibition, affects motivation to feed under a progressive ratio schedule of reinforcement. Pharmacology, Biochemistry, and Behavior. 97: 170-8. PMID 20624416 DOI: 10.1016/J.Pbb.2010.07.002  0.452
2010 Lipina TV, Niwa M, Jaaro-Peled H, Fletcher PJ, Seeman P, Sawa A, Roder JC. Enhanced dopamine function in DISC1-L100P mutant mice: implications for schizophrenia. Genes, Brain, and Behavior. 9: 777-89. PMID 20618446 DOI: 10.1111/J.1601-183X.2010.00615.X  0.348
2010 Bailey CD, De Biasi M, Fletcher PJ, Lambe EK. The nicotinic acetylcholine receptor alpha5 subunit plays a key role in attention circuitry and accuracy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 9241-52. PMID 20610759 DOI: 10.1523/Jneurosci.2258-10.2010  0.636
2010 Hamani C, Diwan M, Macedo CE, Brandão ML, Shumake J, Gonzalez-Lima F, Raymond R, Lozano AM, Fletcher PJ, Nobrega JN. Antidepressant-like effects of medial prefrontal cortex deep brain stimulation in rats. Biological Psychiatry. 67: 117-24. PMID 19819426 DOI: 10.1016/J.Biopsych.2009.08.025  0.394
2010 Hahn M, Chintoh A, Lam L, Mann S, Giacca A, Fletcher P, Remington G. P.3.f.007 Atypical antipsychotics and effects of muscarinic and serotonergic receptor binding on insulin secretion in a rat model European Neuropsychopharmacology. 20: S517. DOI: 10.1016/S0924-977X(10)70772-0  0.309
2009 Fletcher PJ, Tampakeras M, Sinyard J, Slassi A, Isaac M, Higgins GA. Characterizing the effects of 5-HT(2C) receptor ligands on motor activity and feeding behaviour in 5-HT(2C) receptor knockout mice. Neuropharmacology. 57: 259-67. PMID 19501602 DOI: 10.1016/J.Neuropharm.2009.05.011  0.431
2009 Featherstone RE, Burton CL, Coppa-Hopman R, Rizos Z, Sinyard J, Kapur S, Fletcher PJ. Gestational treatment with methylazoxymethanol (MAM) that disrupts hippocampal-dependent memory does not alter behavioural response to cocaine. Pharmacology, Biochemistry, and Behavior. 93: 382-90. PMID 19467255 DOI: 10.1016/J.Pbb.2009.05.010  0.357
2009 Fletcher PJ, Chambers JW, Rizos Z, Chintoh AF. Effects of 5-HT depletion in the frontal cortex or nucleus accumbens on response inhibition measured in the 5-choice serial reaction time test and on a DRL schedule. Behavioural Brain Research. 201: 88-98. PMID 19428621 DOI: 10.1016/J.Bbr.2009.01.036  0.429
2009 Dzung Lê A, Funk D, Harding S, Juzytsch W, Fletcher PJ. The role of noradrenaline and 5-hydroxytryptamine in yohimbine-induced increases in alcohol-seeking in rats. Psychopharmacology. 204: 477-88. PMID 19229522 DOI: 10.1007/S00213-009-1481-Z  0.349
2008 Fletcher PJ, Lê AD, Higgins GA. Serotonin receptors as potential targets for modulation of nicotine use and dependence. Progress in Brain Research. 172: 361-83. PMID 18772042 DOI: 10.1016/S0079-6123(08)00918-7  0.46
2008 Botly LC, Burton CL, Rizos Z, Fletcher PJ. Characterization of methylphenidate self-administration and reinstatement in the rat. Psychopharmacology. 199: 55-66. PMID 18483809 DOI: 10.1007/S00213-008-1093-Z  0.374
2008 Featherstone RE, Rizos Z, Kapur S, Fletcher PJ. A sensitizing regimen of amphetamine that disrupts attentional set-shifting does not disrupt working or long-term memory. Behavioural Brain Research. 189: 170-9. PMID 18299157 DOI: 10.1016/J.Bbr.2007.12.032  0.302
2008 Lê AD, Lê Dzung A, Funk D, Harding S, Juzytsch W, Li Z, Fletcher PJ. Intra-median raphe nucleus (MRN) infusions of muscimol, a GABA-A receptor agonist, reinstate alcohol seeking in rats: role of impulsivity and reward. Psychopharmacology. 195: 605-15. PMID 17891381 DOI: 10.1007/S00213-007-0943-4  0.392
2008 Young EJ, Lipina T, Tam E, Mandel A, Clapcote SJ, Bechard AR, Chambers J, Mount HT, Fletcher PJ, Roder JC, Osborne LR. Reduced fear and aggression and altered serotonin metabolism in Gtf2ird1-targeted mice. Genes, Brain, and Behavior. 7: 224-34. PMID 17680805 DOI: 10.1111/J.1601-183X.2007.00343.X  0.324
2008 Fletcher PJ, Rizos Z, Sinyard J, Tampakeras M, Higgins GA. The 5-HT2C receptor agonist Ro60-0175 reduces cocaine self-administration and reinstatement induced by the stressor yohimbine, and contextual cues. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 1402-12. PMID 17653111 DOI: 10.1038/Sj.Npp.1301509  0.39
2007 Featherstone RE, Kapur S, Fletcher PJ. The amphetamine-induced sensitized state as a model of schizophrenia. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 31: 1556-71. PMID 17884274 DOI: 10.1016/J.Pnpbp.2007.08.025  0.316
2007 Fletcher PJ, Tampakeras M, Sinyard J, Higgins GA. Opposing effects of 5-HT(2A) and 5-HT(2C) receptor antagonists in the rat and mouse on premature responding in the five-choice serial reaction time test. Psychopharmacology. 195: 223-34. PMID 17673981 DOI: 10.1007/S00213-007-0891-Z  0.449
2007 Lee FJ, Pei L, Moszczynska A, Vukusic B, Fletcher PJ, Liu F. Dopamine transporter cell surface localization facilitated by a direct interaction with the dopamine D2 receptor. The Embo Journal. 26: 2127-36. PMID 17380124 DOI: 10.1038/Sj.Emboj.7601656  0.392
2007 Fletcher PJ, Tenn CC, Sinyard J, Rizos Z, Kapur S. A sensitizing regimen of amphetamine impairs visual attention in the 5-choice serial reaction time test: reversal by a D1 receptor agonist injected into the medial prefrontal cortex. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 1122-32. PMID 17047670 DOI: 10.1038/Sj.Npp.1301221  0.417
2007 Featherstone RE, Rizos Z, Nobrega JN, Kapur S, Fletcher PJ. Gestational methylazoxymethanol acetate treatment impairs select cognitive functions: parallels to schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 483-92. PMID 17035930 DOI: 10.1038/Sj.Npp.1301223  0.305
2007 Li M, Fletcher PJ, Kapur S. Time course of the antipsychotic effect and the underlying behavioral mechanisms. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 263-72. PMID 16738541 DOI: 10.1038/Sj.Npp.1301110  0.347
2006 Lovic V, Fleming AS, Fletcher PJ. Early life tactile stimulation changes adult rat responsiveness to amphetamine. Pharmacology, Biochemistry, and Behavior. 84: 497-503. PMID 16860377 DOI: 10.1016/J.Pbb.2006.06.013  0.406
2006 Fletcher PJ, Sinyard J, Higgins GA. The effects of the 5-HT(2C) receptor antagonist SB242084 on locomotor activity induced by selective, or mixed, indirect serotonergic and dopaminergic agonists. Psychopharmacology. 187: 515-25. PMID 16832658 DOI: 10.1007/S00213-006-0453-9  0.484
2006 Placenza FM, Fletcher PJ, Vaccarino FJ, Erb S. Effects of central neurokinin-1 receptor antagonism on cocaine- and opiate-induced locomotor activity and self-administration behaviour in rats. Pharmacology, Biochemistry, and Behavior. 84: 94-101. PMID 16757018 DOI: 10.1016/J.Pbb.2006.04.011  0.398
2006 Lê AD, Funk D, Harding S, Juzytsch W, Fletcher PJ, Shaham Y. Effects of dexfenfluramine and 5-HT3 receptor antagonists on stress-induced reinstatement of alcohol seeking in rats. Psychopharmacology. 186: 82-92. PMID 16521030 DOI: 10.1007/S00213-006-0346-Y  0.406
2006 Natesan S, Reckless GE, Nobrega JN, Fletcher PJ, Kapur S. Dissociation between in vivo occupancy and functional antagonism of dopamine D2 receptors: comparing aripiprazole to other antipsychotics in animal models. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 1854-63. PMID 16319908 DOI: 10.1038/Sj.Npp.1300983  0.435
2005 Fletcher PJ, Tenn CC, Rizos Z, Lovic V, Kapur S. Sensitization to amphetamine, but not PCP, impairs attentional set shifting: reversal by a D1 receptor agonist injected into the medial prefrontal cortex. Psychopharmacology. 183: 190-200. PMID 16220338 DOI: 10.1007/S00213-005-0157-6  0.406
2005 Placenza FM, Vaccarino FJ, Fletcher PJ, Erb S. Activation of central neurokinin-1 receptors induces reinstatement of cocaine-seeking behavior. Neuroscience Letters. 390: 42-7. PMID 16125318 DOI: 10.1016/J.Neulet.2005.07.050  0.378
2005 Tenn CC, Kapur S, Fletcher PJ. Sensitization to amphetamine, but not phencyclidine, disrupts prepulse inhibition and latent inhibition. Psychopharmacology. 180: 366-76. PMID 15856186 DOI: 10.1007/S00213-005-2253-Z  0.331
2004 Limebeer CL, Parker LA, Fletcher PJ. 5,7-dihydroxytryptamine lesions of the dorsal and median raphe nuclei interfere with lithium-induced conditioned gaping, but not conditioned taste avoidance, in rats. Behavioral Neuroscience. 118: 1391-9. PMID 15598147 DOI: 10.1037/0735-7044.118.6.1391  0.341
2004 Li M, Parkes J, Fletcher PJ, Kapur S. Evaluation of the motor initiation hypothesis of APD-induced conditioned avoidance decreases. Pharmacology, Biochemistry, and Behavior. 78: 811-9. PMID 15301940 DOI: 10.1016/J.Pbb.2004.05.023  0.352
2004 Placenza FM, Fletcher PJ, Rotzinger S, Vaccarino FJ. Infusion of the substance P analogue, DiMe-C7, into the ventral tegmental area induces reinstatement of cocaine-seeking behaviour in rats. Psychopharmacology. 177: 111-20. PMID 15167979 DOI: 10.1007/S00213-004-1912-9  0.412
2004 Fletcher PJ, Sinyard J, Salsali M, Baker GB. Fluoxetine, but not sertraline or citalopram, potentiates the locomotor stimulant effect of cocaine: possible pharmacokinetic effects. Psychopharmacology. 174: 406-13. PMID 14740149 DOI: 10.1007/S00213-003-1747-9  0.344
2004 Fletcher PJ, Chintoh AF, Sinyard J, Higgins GA. Injection of the 5-HT2C receptor agonist Ro60-0175 into the ventral tegmental area reduces cocaine-induced locomotor activity and cocaine self-administration. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 308-18. PMID 14666118 DOI: 10.1038/Sj.Npp.1300319  0.432
2003 Higgins GA, Fletcher PJ. Serotonin and drug reward: focus on 5-HT2C receptors. European Journal of Pharmacology. 480: 151-62. PMID 14623358 DOI: 10.1016/J.Ejphar.2003.08.102  0.442
2003 Tenn CC, Fletcher PJ, Kapur S. Amphetamine-sensitized animals show a sensorimotor gating and neurochemical abnormality similar to that of schizophrenia. Schizophrenia Research. 64: 103-14. PMID 14613675 DOI: 10.1016/S0920-9964(03)00009-4  0.361
2003 Higgins GA, Enderlin M, Haman M, Fletcher PJ. The 5-HT2A receptor antagonist M100,907 attenuates motor and 'impulsive-type' behaviours produced by NMDA receptor antagonism. Psychopharmacology. 170: 309-19. PMID 12904968 DOI: 10.1007/S00213-003-1549-0  0.44
2003 Schwartz RA, Greenwald ER, Fletcher PJ, Houle S, DaSilva JN. Up-regulated dopamine D1 receptor binding can be detected in vivo following repeated SCH 23390, but not SKF 81297 or 6-hydroxydopamine, treatments. European Journal of Pharmacology. 459: 195-201. PMID 12524146 DOI: 10.1016/S0014-2999(02)02850-9  0.411
2002 Hebb MO, Lang AE, Fletcher PJ, Chambers JW, Lozano AM. Neonatal ablation of the nigrostriatal dopamine pathway does not influence limb development in rats. Experimental Neurology. 177: 547-56. PMID 12429200 DOI: 10.1006/Exnr.2002.8005  0.364
2002 Fletcher PJ, Grottick AJ, Higgins GA. Differential effects of the 5-HT(2A) receptor antagonist M100907 and the 5-HT(2C) receptor antagonist SB242084 on cocaine-induced locomotor activity, cocaine self-administration and cocaine-induced reinstatement of responding. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 27: 576-86. PMID 12377394 DOI: 10.1016/S0893-133X(02)00342-1  0.418
2002 Lê AD, Harding S, Juzytsch W, Fletcher PJ, Shaham Y. The role of corticotropin-releasing factor in the median raphe nucleus in relapse to alcohol. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 7844-9. PMID 12223536 DOI: 10.1523/Jneurosci.22-18-07844.2002  0.357
2002 Ross BM, Brooks RJ, Lee M, Kalasinsky KS, Vorce SP, Seeman M, Fletcher PJ, Turenne SD. Cyclooxygenase inhibitor modulation of dopamine-related behaviours. European Journal of Pharmacology. 450: 141-51. PMID 12206852 DOI: 10.1016/S0014-2999(02)02104-0  0.424
2002 Fletcher PJ, Korth KM, Robinson SR, Baker GB. Multiple 5-HT receptors are involved in the effects of acute MDMA treatment: studies on locomotor activity and responding for conditioned reinforcement. Psychopharmacology. 162: 282-91. PMID 12122486 DOI: 10.1007/S00213-002-1104-4  0.482
2002 Fletcher PJ, Azampanah A, Korth KM. Activation of 5-HT(1B) receptors in the nucleus accumbens reduces self-administration of amphetamine on a progressive ratio schedule. Pharmacology, Biochemistry, and Behavior. 71: 717-25. PMID 11888563 DOI: 10.1016/S0091-3057(01)00717-1  0.476
2002 Higgins GA, Fletcher PJ. Serotonin-based therapeutics. Pharmacology, Biochemistry, and Behavior. 71: 531-2. PMID 11888545 DOI: 10.1016/S0091-3057(01)00739-0  0.351
2001 Sills TL, Azampanah A, Fletcher PJ. The adenosine A2A agonist CGS 21680 reverses the reduction in prepulse inhibition of the acoustic startle response induced by phencyclidine, but not by apomorphine and amphetamine. Psychopharmacology. 156: 187-93. PMID 11549222 DOI: 10.1007/S002130100777  0.419
2001 Fletcher PJ, Robinson SR, Slippoy DL. Pre-exposure to (+/-)3,4-methylenedioxy-methamphetamine (MDMA) facilitates acquisition of intravenous cocaine self-administration in rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 25: 195-203. PMID 11425503 DOI: 10.1016/S0893-133X(01)00222-6  0.374
2001 Fletcher PJ, Selhi ZF, Azampanah A, Sills TL. Reduced brain serotonin activity disrupts prepulse inhibition of the acoustic startle reflex. Effects of 5,7-dihydroxytryptamine and p-chlorophenylalanine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 24: 399-409. PMID 11182535 DOI: 10.1016/S0893-133X(00)00215-3  0.466
2000 Brown CM, Coscina DV, Fletcher PJ. The rewarding properties of neuropeptide Y in perifornical hypothalamus vs. nucleus accumbens. Peptides. 21: 1279-87. PMID 11035216 DOI: 10.1016/S0196-9781(00)00270-9  0.366
2000 Karasinska JM, George SR, El-Ghundi M, Fletcher PJ, O'Dowd BF. Modification of dopamine D(1) receptor knockout phenotype in mice lacking both dopamine D(1) and D(3) receptors. European Journal of Pharmacology. 399: 171-81. PMID 10884517 DOI: 10.1016/S0014-2999(00)00347-2  0.36
2000 Sills TL, Greenshaw AJ, Baker GB, Fletcher PJ. Subchronic fluoxetine treatment induces a transient potentiation of amphetamine-induced hyperlocomotion: possible pharmacokinetic interaction. Behavioural Pharmacology. 11: 109-16. PMID 10877115 DOI: 10.1097/00008877-200004000-00002  0.382
2000 Wadenberg MG, Sills TL, Fletcher PJ, Kapur S. Antipsychoticlike effects of amoxapine, without catalepsy, using the prepulse inhibition of the acoustic startle reflex test in rats. Biological Psychiatry. 47: 670-6. PMID 10745061 DOI: 10.1016/S0006-3223(99)00267-X  0.467
1999 Fletcher PJ, Korth KM. RU-24969 disrupts d-amphetamine self-administration and responding for conditioned reward via stimulation of 5-HT1B receptors. Behavioural Pharmacology. 10: 183-93. PMID 10780831  0.374
1999 Fletcher PJ, Korth KM, Chambers JW. Selective destruction of brain serotonin neurons by 5,7-dihydroxytryptamine increases responding for a conditioned reward. Psychopharmacology. 147: 291-9. PMID 10639688 DOI: 10.1007/S002130051170  0.458
1999 El-Ghundi M, Fletcher PJ, Drago J, Sibley DR, O'Dowd BF, George SR. Spatial learning deficit in dopamine D(1) receptor knockout mice. European Journal of Pharmacology. 383: 95-106. PMID 10585522 DOI: 10.1016/S0014-2999(99)00573-7  0.328
1999 Fletcher PJ, Korth KM, Chambers JW. Depletion of brain serotonin following intra-raphe injections of 5,7- dihydroxytryptamine does not alter d-amphetamine self-administration across different schedule and access conditions Psychopharmacology. 146: 185-193. PMID 10525754 DOI: 10.1007/S002130051105  0.444
1999 Sills TL, Greenshaw AJ, Baker GB, Fletcher PJ. The potentiating effect of sertraline and fluoxetine on amphetamine-induced locomotor activity is not mediated by serotonin. Psychopharmacology. 143: 426-32. PMID 10367561 DOI: 10.1007/S002130050968  0.322
1999 Sills TL, Azampanah A, Fletcher PJ. The adenosine A1 receptor agonist N6-cyclopentyladenosine blocks the disruptive effect of phencyclidine on prepulse inhibition of the acoustic startle response in the rat European Journal of Pharmacology. 369: 325-329. PMID 10225370 DOI: 10.1016/S0014-2999(99)00088-6  0.369
1999 Fletcher PJ, Korth KM. Activation of 5-HT(1B) receptors in the nucleus accumbens reduces amphetamine-induced enhancement of responding for conditioned reward Psychopharmacology. 142: 165-174. PMID 10102769 DOI: 10.1007/S002130050876  0.491
1999 Sills TL, Greenshaw AJ, Baker GB, Fletcher PJ. Acute fluoxetine treatment potentiates amphetamine hyperactivity and amphetamine-induced nucleus accumbens dopamine release: possible pharmacokinetic interaction. Psychopharmacology. 141: 421-7. PMID 10090650 DOI: 10.1007/S002130050852  0.435
1998 Brown CM, Fletcher PJ, Coscina DV. Neuropeptide Y-induced operant responding for sucrose is not mediated by dopamine. Peptides. 19: 1667-73. PMID 9880070 DOI: 10.1016/S0196-9781(98)00117-X  0.439
1998 Fletcher PJ, Korth KM, Sabijan MS, Desousa NJ. Injections of D-amphetamine into the ventral pallidum increase locomotor activity and responding for conditioned reward: A comparison with injections into the nucleus accumbens Brain Research. 805: 29-40. PMID 9733910 DOI: 10.1016/S0006-8993(98)00633-7  0.41
1998 El-Ghundi M, George SR, Drago J, Fletcher PJ, Fan T, Nguyen T, Liu C, Sibley DR, Westphal H, O'Dowd BF. Disruption of dopamine D1 receptor gene expression attenuates alcohol-seeking behavior. European Journal of Pharmacology. 353: 149-58. PMID 9726645 DOI: 10.1016/S0014-2999(98)00414-2  0.326
1998 Currie PJ, Coscina DV, Fletcher PJ. Reversal of fenfluramine and fluoxetine anorexia by 8-OH-DPAT is attenuated following raphe injection of 5,7-dihydroxytryptamine. Brain Research. 800: 62-8. PMID 9685586 DOI: 10.1016/S0006-8993(98)00497-1  0.438
1998 Fletcher PJ. A comparison of the effects of risperidone, raclopride, and ritanserin on intravenous self-administration of d-amphetamine Pharmacology Biochemistry and Behavior. 60: 55-60. PMID 9610924 DOI: 10.1016/S0091-3057(97)00559-5  0.453
1998 Brown CM, Fletcher PJ, Coscina DV. Acute amino acid loads that deplete brain serotonin fail to alter behavior. Pharmacology, Biochemistry, and Behavior. 59: 115-21. PMID 9443545 DOI: 10.1016/S0091-3057(97)00381-X  0.366
1997 Sills TL, Fletcher PJ. Fluoxetine attenuates morphine-induced locomotion and blocks morphine-sensitization European Journal of Pharmacology. 337: 161-164. PMID 9430410 DOI: 10.1016/S0014-2999(97)01308-3  0.353
1997 Fletcher PJ, Higgins GA. Differential effects of ondansetron and α-flupenthixol on responding for conditioned reward Psychopharmacology. 134: 64-72. PMID 9399368 DOI: 10.1007/S002130050426  0.506
1996 Fletcher PJ. Injection of 5-HT into the nucleus accumbens reduces the effects of d-amphetamine on responding for conditioned reward Psychopharmacology. 126: 62-69. PMID 8853218 DOI: 10.1007/Bf02246412  0.473
1995 Fletcher PJ. Effects of d-fenfluramine and metergoline on responding for conditioned reward and the response potentiating effect of nucleus accumbens d-amphetamine Psychopharmacology. 118: 155-163. PMID 7617802 DOI: 10.1007/BF02245834  0.383
1995 Fletcher PJ. Effects of combined or separate 5,7-dihydroxytryptamine lesions of the dorsal and median raphe nuclei on responding maintained by a DRL 20s schedule of food reinforcement Brain Research. 675: 45-54. PMID 7540930 DOI: 10.1016/0006-8993(95)00037-Q  0.438
1995 Fletcher PJ, Tampakeras M, Yeomans JS. Median raphe injections of 8-OH-DPAT lower frequency thresholds for lateral hypothalamic self-stimulation. Pharmacology, Biochemistry, and Behavior. 52: 65-71. PMID 7501680 DOI: 10.1016/0091-3057(94)00441-K  0.46
1995 Wang Y, Joharchi N, Fletcher PJ, Sellers EM, Higgins GA. Further studies to examine the nature of dexfenfluramine-induced suppression of heroin self-administration Psychopharmacology. 120: 134-141. PMID 7480544 DOI: 10.1007/Bf02246185  0.434
1994 Currie PJ, Fletcher PJ, Coscina DV. Administration of 8-OH-DPAT into the midbrain raphe nuclei: effects on medial hypothalamic NE-induced feeding. The American Journal of Physiology. 266: R1645-51. PMID 8203645 DOI: 10.1152/Ajpregu.1994.266.5.R1645  0.408
1994 Tomkins DM, Sellers EM, Fletcher PJ. Median and dorsal raphe injections of the 5-HT1A agonist, 8-OH-DPAT, and the GABAA agonist, muscimol, increase voluntary ethanol intake in wistar rats Neuropharmacology. 33: 349-358. PMID 7984273 DOI: 10.1016/0028-3908(94)90065-5  0.366
1993 Fletcher PJ. A comparison of the effects of dorsal or median raphe injections of 8-OH-DPAT in three operant tasks measuring response inhibition Behavioural Brain Research. 54: 187-197. PMID 8323715 DOI: 10.1016/0166-4328(93)90078-5  0.46
1993 Fletcher PJ, Coscina DV. Injecting 5-HT into the PVN does not prevent feeding induced by injecting 8-OH-DPAT into the raphe. Pharmacology, Biochemistry, and Behavior. 46: 487-91. PMID 8265706 DOI: 10.1016/0091-3057(93)90385-7  0.426
1993 Fletcher PJ, Currie PJ, Chambers JW, Coscina DV. Radiofrequency lesions of the PVN fail to modify the effects of serotonergic drugs on food intake. Brain Research. 630: 1-9. PMID 8118676 DOI: 10.1016/0006-8993(93)90635-Z  0.37
1993 Fletcher PJ, Ming ZH, Higgins GA. Conditioned place preference induced by microinjection of 8-OH-DPAT into the dorsal or median raphe nucleus Psychopharmacology. 113: 31-36. PMID 7862825 DOI: 10.1007/Bf02244330  0.457
1992 Higgins GA, Tomkins DM, Fletcher PJ, Sellers EM. Effect of drugs influencing 5-HT function on ethanol drinking and feeding behaviour in rats: Studies using a drinkometer system Neuroscience and Biobehavioral Reviews. 16: 535-552. PMID 1480350 DOI: 10.1016/S0149-7634(05)80195-2  0.425
1992 Fletcher PJ, Ming ZH, Zack MH, Coscina DV. A comparison of the effects of the 5-HT1 agonists TFMPP and RU 24969 on feeding following peripheral or medial hypothalamic injection. Brain Research. 580: 265-72. PMID 1387034 DOI: 10.1016/0006-8993(92)90953-7  0.377
1991 Fletcher PJ. Opiate antagonists inhibit feeding induced by 8-OH-DPAT: possible mediation in the nucleus accumbens Brain Research. 560: 260-267. PMID 1836972 DOI: 10.1016/0006-8993(91)91241-R  0.493
1991 Fletcher PJ. Dopamine receptor blockade in nucleus accumbens or caudate nucleus differentially affects feeding induced by 8-OH-DPAT injected into dorsal or median raphe Brain Research. 552: 181-189. PMID 1833034 DOI: 10.1016/0006-8993(91)90082-7  0.484
1991 Fletcher PJ, Zack MH, Coscina DV. Influence of taste and food texture on the feeding responses induced by 8-OH-DPAT and gepirone. Psychopharmacology. 104: 302-6. PMID 1681556 DOI: 10.1007/Bf02246027  0.347
1990 Fletcher PJ, Davies M. Dorsal raphe microinjection of 5-HT and indirect 5-HT agonists induces feeding in rats European Journal of Pharmacology. 184: 265-271. PMID 2150377 DOI: 10.1016/0014-2999(90)90618-G  0.315
1990 Fletcher PJ, Davies M. The involvement of 5-hydroxytryptaminergic and dopaminergic mechanisms in the eating induced by buspirone, gepirone and ipsapirone British Journal of Pharmacology. 99: 519-525. PMID 2139586 DOI: 10.1111/j.1476-5381.1990.tb12961.x  0.346
1990 Fletcher PJ, Davies M. A pharmacological analysis of the eating response induced by 8-OH-DPAT injected into the dorsal raphé nucleus reveals the involvement of a dopaminergic mechanism Psychopharmacology. 100: 188-194. PMID 2137632 DOI: 10.1007/BF02244404  0.366
1989 Fletcher PJ, Paterson IA. A comparison of the effects of tryptamine and 5-hydroxytryptamine on feeding following injection into the paraventricular nucleus of the hypothalamus Pharmacology, Biochemistry and Behavior. 32: 907-911. PMID 2529575 DOI: 10.1016/0091-3057(89)90057-9  0.304
1989 Fletcher PJ. Tryptamine impairs the acquisition of a one-way active avoidance task Pharmacology, Biochemistry and Behavior. 32: 317-321. PMID 2525258 DOI: 10.1016/0091-3057(89)90249-9  0.346
1988 Fletcher PJ. Increased food intake in satiated rats induced by the 5-HT antagonists methysergide, metergoline and ritanserin Psychopharmacology. 96: 237-242. PMID 3148151 DOI: 10.1007/BF00177567  0.304
1985 Fletcher PJ, Burton MJ. The anorectic action of peripherally administered 5-HT is enhanced by vagotomy Physiology and Behavior. 34: 861-866. PMID 4059374 DOI: 10.1016/0031-9384(85)90004-6  0.307
1984 Fletcher PJ, Burton MJ. Effects of manipulations of peripheral serotonin on feeding and drinking in the rat Pharmacology, Biochemistry and Behavior. 20: 835-840. PMID 6463070 DOI: 10.1016/0091-3057(84)90002-9  0.312
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