Sarah Kimmins, Ph.D.

Affiliations: 
Dalhousie University, Halifax, Nova Scotia, Canada 
Area:
evolutionary developmental biology, skeletal biology, neural crest
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"Sarah Kimmins"

Parents

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Brian K. Hall grad student 2003 Dalhousie University
 (Endocrine and paracrine regulation of integrin alpha(v)beta(3) in bovine endometrium.)
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Publications

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Lismer A, Dumeaux V, Lafleur C, et al. (2021) Histone H3 lysine 4 trimethylation in sperm is transmitted to the embryo and associated with diet-induced phenotypes in the offspring. Developmental Cell
Gagnon MF, Lafleur C, Landry-Cuerrier M, et al. (2020) Torpor expression is associated with differential spermatogenesis in hibernating eastern chipmunks. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
Lessard M, Herst PM, Charest PL, et al. (2019) Prenatal Exposure to Environmentally-Relevant Contaminants Perturbs Male Reproductive Parameters Across Multiple Generations that are Partially Protected by Folic Acid Supplementation. Scientific Reports. 9: 13829
Chan D, Shao X, Dumargne MC, et al. (2019) Customized MethylC-Capture Sequencing to Evaluate Variation in the Human Sperm DNA Methylome Representative of Altered Folate Metabolism. Environmental Health Perspectives. 127: 87002
Lambrot R, Siklenka K, Lafleur C, et al. (2019) The Genomic Distribution of Histone H3K4me2 in Spermatogonia is Highly Conserved in Sperm. Biology of Reproduction
Maurice C, Kaczmarczyk M, Côté N, et al. (2018) Prenatal exposure to an environmentally relevant mixture of Canadian Arctic contaminants decreases male reproductive function in an aging rat model. Journal of Developmental Origins of Health and Disease. 1-8
Siklenka K, Erkek S, Godmann M, et al. (2015) Disruption of histone methylation in developing sperm impairs offspring health transgenerationally. Science (New York, N.Y.). 350: aab2006
Lambrot R, Lafleur C, Kimmins S. (2015) The histone demethylase KDM1A is essential for the maintenance and differentiation of spermatogonial stem cells and progenitors. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology
Boerboom D, Kumar V, Boyer A, et al. (2015) β-catenin stabilization in gonadotropes impairs FSH synthesis in male mice in vivo. Endocrinology. 156: 323-33
Lambrot R, Xu C, Saint-Phar S, et al. (2013) Low paternal dietary folate alters the mouse sperm epigenome and is associated with negative pregnancy outcomes. Nature Communications. 4: 2889
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