Michael A. Mandell, Ph.D.

Biology & Biomedical Sciences (Molecular Microbiology & Microbial Pathogenesis) Washington University, Saint Louis, St. Louis, MO 
"Michael Mandell"


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Stephen M. Beverley grad student 2011 Washington University
 (Leishmania persistence and host-cell interactions.)
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Mandell MA, Beverley SM. (2017) Continual renewal and replication of persistent Leishmania major parasites in concomitantly immune hosts. Proceedings of the National Academy of Sciences of the United States of America
Mandell MA, Beverley SM. (2016) Concomitant Immunity Induced by Persistent Leishmania major Does Not Preclude Secondary Re-Infection: Implications for Genetic Exchange, Diversity and Vaccination. Plos Neglected Tropical Diseases. 10: e0004811
Kimura T, Mandell M, Deretic V. (2016) Precision autophagy directed by receptor regulators - emerging examples within the TRIM family. Journal of Cell Science. 129: 881-91
Chauhan S, Ahmed Z, Bradfute SB, et al. (2015) Pharmaceutical screen identifies novel target processes for activation of autophagy with a broad translational potential. Nature Communications. 6: 8620
Kimura T, Jain A, Choi SW, et al. (2015) TRIM-mediated precision autophagy targets cytoplasmic regulators of innate immunity. The Journal of Cell Biology
Chauhan S, Mandell MA, Deretic V. (2015) Mechanism of action of the tuberculosis and Crohn disease risk factor IRGM in autophagy. Autophagy. 0
Ponpuak M, Mandell MA, Kimura T, et al. (2015) Secretory autophagy. Current Opinion in Cell Biology. 35: 106-116
Chauhan S, Mandell MA, Deretic V. (2015) IRGM Governs the Core Autophagy Machinery to Conduct Antimicrobial Defense. Molecular Cell. 58: 507-21
Deretic V, Kimura T, Timmins G, et al. (2015) Immunologic manifestations of autophagy. The Journal of Clinical Investigation. 125: 75-84
Mandell MA, Kimura T, Jain A, et al. (2014) TRIM proteins regulate autophagy: TRIM5 is a selective autophagy receptor mediating HIV-1 restriction. Autophagy. 10: 2387-8
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